{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T09:37:37Z","timestamp":1771061857797,"version":"3.50.1"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Jpn J Ophthalmol"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1007\/s10384-020-00791-8","type":"journal-article","created":{"date-parts":[[2021,1,6]],"date-time":"2021-01-06T02:02:59Z","timestamp":1609898579000},"page":"144-153","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Role of oncostatin M in the pathogenesis of vernal keratoconjunctivitis: focus on tissue remodeling"],"prefix":"10.1007","volume":"65","author":[{"given":"Keitaro","family":"Mashimo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayumi","family":"Usui-Ouchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yousuke","family":"Ito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rei","family":"Wakasa-Arai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norihiko","family":"Yokoi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Kawasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Murakami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Matsuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuyuki","family":"Ebihara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,1,6]]},"reference":[{"key":"791_CR1","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1007\/s10254-003-0013-1","volume":"149","author":"M Tanaka","year":"2003","unstructured":"Tanaka M, Miyajima A. Oncostatin M: a multifunctional cytokine. Rev Physiol Biochem Pharmacol. 2003;149:39\u201352.","journal-title":"Rev Physiol Biochem Pharmacol"},{"key":"791_CR2","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1038\/s41577-018-0066-7","volume":"18","author":"SA Jones","year":"2018","unstructured":"Jones SA, Jenkins BJ. Recent insights into targeting the IL-6 cytokine family in inflammatory diseases and cancer. Nat Rev Immunol. 2018;18:773\u201389.","journal-title":"Nat Rev Immunol"},{"key":"791_CR3","doi-asserted-by":"publisher","first-page":"4615","DOI":"10.4049\/jimmunol.178.7.4615","volume":"178","author":"K Boniface","year":"2007","unstructured":"Boniface K, Diveu C, Morel F, Pedretti N, Froger J, Ravon E, et al. Oncostatin M secreted by skin infiltrating T lymphocytes is a potent keratinocyte activator involved in skin inflammation. J Immunol. 2007;178:4615\u201322.","journal-title":"J Immunol"},{"key":"791_CR4","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.4049\/jimmunol.0903476","volume":"186","author":"DK Fritz","year":"2011","unstructured":"Fritz DK, Kerr C, Fattouh R, Llop-Guevara A, Khan WI, Jordana M, et al. A mouse model of airway disease: oncostatin M-induced pulmonary eosinophilia, goblet cell hyperplasia, and airway hyperresponsiveness are STAT6 dependent, and interstitial pulmonary fibrosis is STAT6 independent. J Immunol. 2011;186:1107\u201318.","journal-title":"J Immunol"},{"key":"791_CR5","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1165\/rcmb.2012-0460OC","volume":"49","author":"KY Nagahama","year":"2013","unstructured":"Nagahama KY, Togo S, Holz O, Magnussen H, Liu X, Seyama K, et al. Oncostatin M modulates fibroblast function via signal transducers and activators of transcription proteins-3. Am J Respir Cell Mol Biol. 2013;49:582\u201391.","journal-title":"Am J Respir Cell Mol Biol"},{"key":"791_CR6","doi-asserted-by":"publisher","first-page":"2213","DOI":"10.1097\/01.mlg.0000187819.89889.4a","volume":"115","author":"HJ Kang","year":"2005","unstructured":"Kang HJ, Kang JS, Lee SH, Hwang SJ, Chae SW, Woo JS, et al. Upregulation of oncostatin M in allergic rhinitis. Laryngoscope. 2005;115:2213\u20136.","journal-title":"Laryngoscope"},{"key":"791_CR7","doi-asserted-by":"publisher","first-page":"7243","DOI":"10.4049\/jimmunol.181.10.7243","volume":"181","author":"A Mozaffarian","year":"2008","unstructured":"Mozaffarian A, Brewer AW, Trueblood ES, Luzina IG, Todd NW, Atamas SP, et al. Mechanisms of oncostatin M-induced pulmonary inflammation and fibrosis. J Immunol. 2008;181:7243\u201353.","journal-title":"J Immunol"},{"key":"791_CR8","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1097\/00007611-198901000-00027","volume":"82","author":"RB Johnson","year":"1989","unstructured":"Johnson RB. Use of NSAIDs in long-distance runners: a risk factor for sudden death? South Med J. 1989;82:95.","journal-title":"South Med J"},{"key":"791_CR9","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1038\/sj.bjp.0704769","volume":"136","author":"AK Scaffidi","year":"2002","unstructured":"Scaffidi AK, Mutsaers SE, Moodley YP, McAnulty RJ, Laurent GJ, Thompson PJ, et al. Oncostatin M stimulates proliferation, induces collagen production and inhibits apoptosis of human lung fibroblasts. Br J Pharmacol. 2002;136:793\u2013801.","journal-title":"Br J Pharmacol"},{"key":"791_CR10","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1111\/1523-1747.ep12613623","volume":"104","author":"MR Duncan","year":"1995","unstructured":"Duncan MR, Hasan A, Berman B. Oncostatin M stimulates collagen and glycosaminoglycan production by cultured normal dermal fibroblasts: insensitivity of sclerodermal and keloidal fibroblasts. J Invest Dermatol. 1995;104:128\u201333.","journal-title":"J Invest Dermatol"},{"key":"791_CR11","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1007\/s109-1998-8105-3","volume":"76","author":"B Bamber","year":"1998","unstructured":"Bamber B, Reife RA, Haugen HS, Clegg CH. Oncostatin M stimulates excessive extracellular matrix accumulation in a transgenic mouse model of connective tissue disease. J Mol Med (Berl). 1998;76:61\u20139.","journal-title":"J Mol Med (Berl)"},{"key":"791_CR12","doi-asserted-by":"publisher","first-page":"1003","DOI":"10.1038\/labinvest.2014.81","volume":"94","author":"S Wong","year":"2014","unstructured":"Wong S, Botelho FM, Rodrigues RM, Richards CD. Oncostatin M overexpression induces matrix deposition, STAT3 activation, and SMAD1 Dysregulation in lungs of fibrosis-resistant BALB\/c mice. Lab Invest. 2014;94:1003\u201316.","journal-title":"Lab Invest"},{"key":"791_CR13","doi-asserted-by":"publisher","first-page":"F1014","DOI":"10.1152\/ajprenal.00123.2011","volume":"301","author":"R Sarkozi","year":"2011","unstructured":"Sarkozi R, Hauser C, Noppert SJ, Kronbichler A, Pirklbauer M, Haller VM, et al. Oncostatin M is a novel inhibitor of TGF-beta1-induced matricellular protein expression. Am J Physiol Renal Physiol. 2011;301:F1014\u201325.","journal-title":"Am J Physiol Renal Physiol"},{"key":"791_CR14","doi-asserted-by":"publisher","first-page":"2824","DOI":"10.1038\/s41467-019-10859-w","volume":"10","author":"H Abe","year":"2019","unstructured":"Abe H, Takeda N, Isagawa T, Semba H, Nishimura S, Morioka MS, et al. Macrophage hypoxia signaling regulates cardiac fibrosis via Oncostatin M. Nat Commun. 2019;10:2824.","journal-title":"Nat Commun"},{"key":"791_CR15","doi-asserted-by":"publisher","first-page":"2113","DOI":"10.1038\/s41598-019-38572-0","volume":"9","author":"V Huguier","year":"2019","unstructured":"Huguier V, Giot JP, Simonneau M, Levillain P, Charreau S, Garcia M, et al. Oncostatin M exerts a protective effect against excessive scarring by counteracting the inductive effect of TGFbeta1 on fibrosis markers. Sci Rep. 2019;9:2113.","journal-title":"Sci Rep"},{"key":"791_CR16","doi-asserted-by":"publisher","first-page":"2465","DOI":"10.1167\/iovs.12-10664","volume":"54","author":"S Iwamoto","year":"2013","unstructured":"Iwamoto S, Asada Y, Ebihara N, Hori K, Okayama Y, Kashiwakura J, et al. Interaction between conjunctival epithelial cells and mast cells induces CCL2 expression and piecemeal degranulation in mast cells. Invest Ophthalmol Vis Sci. 2013;54:2465\u201373.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"791_CR17","doi-asserted-by":"publisher","first-page":"3820","DOI":"10.1167\/iovs.06-0293","volume":"47","author":"H Tanioka","year":"2006","unstructured":"Tanioka H, Kawasaki S, Yamasaki K, Ang LP, Koizumi N, Nakamura T, et al. Establishment of a cultivated human conjunctival epithelium as an alternative tissue source for autologous corneal epithelial transplantation. Invest Ophthalmol Vis Sci. 2006;47:3820\u20137.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"791_CR18","doi-asserted-by":"publisher","first-page":"758","DOI":"10.1167\/iovs.09-3379","volume":"51","author":"LP Ang","year":"2010","unstructured":"Ang LP, Tanioka H, Kawasaki S, Ang LP, Yamasaki K, Do TP, et al. Cultivated human conjunctival epithelial transplantation for total limbal stem cell deficiency. Invest Ophthalmol Vis Sci. 2010;51:758\u201364.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"791_CR19","first-page":"166","volume":"110","author":"S Kinoshita","year":"2012","unstructured":"Kinoshita S, Kawasaki S, Kitazawa K, Shinomiya K. Establishment of a human conjunctival epithelial cell line lacking the functional TACSTD2 gene (an American Ophthalmological Society thesis). Trans Am Ophthalmol Soc. 2012;110:166\u201377.","journal-title":"Trans Am Ophthalmol Soc"},{"key":"791_CR20","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1167\/iovs.09-4183","volume":"51","author":"A Matsuda","year":"2010","unstructured":"Matsuda A, Ebihara N, Yokoi N, Kawasaki S, Tanioka H, Inatomi T, et al. Functional role of thymic stromal lymphopoietin in chronic allergic keratoconjunctivitis. Invest Ophthalmol Vis Sci. 2010;51:151\u20135.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"791_CR21","doi-asserted-by":"publisher","first-page":"1966","DOI":"10.1016\/j.jaci.2016.10.039","volume":"139","author":"KL Pothoven","year":"2017","unstructured":"Pothoven KL, Norton JE, Suh LA, Carter RG, Harris KE, Biyasheva A, et al. Neutrophils are a major source of the epithelial barrier disrupting cytokine oncostatin M in patients with mucosal airways disease. J Allergy Clin Immunol. 2017;139:1966\u201378.","journal-title":"J Allergy Clin Immunol"},{"key":"791_CR22","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1006\/cyto.2002.1023","volume":"17","author":"T Suda","year":"2002","unstructured":"Suda T, Chida K, Todate A, Ide K, Asada K, Nakamura Y, et al. Oncostatin M production by human dendritic cells in response to bacterial products. Cytokine. 2002;17:335\u201340.","journal-title":"Cytokine"},{"key":"791_CR23","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1016\/j.jaci.2007.08.054","volume":"121","author":"P Salamon","year":"2008","unstructured":"Salamon P, Shoham NG, Puxeddu I, Paitan Y, Levi-Schaffer F, Mekori YA. Human mast cells release oncostatin M on contact with activated T cells: possible biologic relevance. J Allergy Clin Immunol. 2008;121:448\u201355.","journal-title":"J Allergy Clin Immunol"},{"key":"791_CR24","doi-asserted-by":"publisher","first-page":"1413","DOI":"10.1182\/blood.V93.4.1413","volume":"93","author":"A Grenier","year":"1999","unstructured":"Grenier A, Dehoux M, Boutten A, Arce-Vicioso M, Durand G, Gougerot-Pocidalo MA, et al. Oncostatin M production and regulation by human polymorphonuclear neutrophils. Blood. 1999;93:1413\u201321.","journal-title":"Blood"},{"key":"791_CR25","doi-asserted-by":"publisher","first-page":"5575","DOI":"10.4049\/jimmunol.180.8.5575","volume":"180","author":"SM Uriarte","year":"2008","unstructured":"Uriarte SM, Powell DW, Luerman GC, Merchant ML, Cummins TD, Jog NR, et al. Comparison of proteins expressed on secretory vesicle membranes and plasma membranes of human neutrophils. J Immunol. 2008;180:5575\u201381.","journal-title":"J Immunol"},{"key":"791_CR26","doi-asserted-by":"publisher","first-page":"3847","DOI":"10.3390\/ijms20163847","volume":"20","author":"D Young","year":"2019","unstructured":"Young D, Das N, Anowai A, Dufour A. Matrix metalloproteases as influencers of the cells\u2019 social media. Int J Mol Sci. 2019;20:3847.","journal-title":"Int J Mol Sci"},{"key":"791_CR27","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.cyto.2014.11.007","volume":"72","author":"RE Ryan","year":"2015","unstructured":"Ryan RE, Martin B, Mellor L, Jacob RB, Tawara K, McDougal OM, et al. Oncostatin M binds to extracellular matrix in a bioactive conformation: implications for inflammation and metastasis. Cytokine. 2015;72:71\u201385.","journal-title":"Cytokine"},{"key":"791_CR28","doi-asserted-by":"publisher","first-page":"3052","DOI":"10.1167\/iovs.02-0766","volume":"44","author":"A Leonardi","year":"2003","unstructured":"Leonardi A, Brun P, Abatangelo G, Plebani M, Secchi AG. Tear levels and activity of matrix metalloproteinase (MMP)-1 and MMP-9 in vernal keratoconjunctivitis. Invest Ophthalmol Vis Sci. 2003;44:3052\u20138.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"791_CR29","first-page":"202","volume":"19","author":"C Turato","year":"2015","unstructured":"Turato C, Pontisso P. SERPINB3 (serpin peptidase inhibitor, clade B (ovalbumin), member 3). Atlas Genet Cytogenet Oncol Haematol. 2015;19:202\u20139.","journal-title":"Atlas Genet Cytogenet Oncol Haematol"},{"key":"791_CR30","doi-asserted-by":"publisher","first-page":"1368","DOI":"10.3390\/ijms18071368","volume":"18","author":"M Reithofer","year":"2017","unstructured":"Reithofer M, Jahn-Schmid B. Allergens with protease activity from house dust mites. Int J Mol Sci. 2017;18:1368.","journal-title":"Int J Mol Sci"},{"issue":"737\u201346","key":"791_CR31","first-page":"e4","volume":"136","author":"KL Pothoven","year":"2015","unstructured":"Pothoven KL, Norton JE, Hulse KE, Suh LA, Carter RG, Rocci E, et al. Oncostatin M promotes mucosal epithelial barrier dysfunction, and its expression is increased in patients with eosinophilic mucosal disease. J Allergy Clin Immunol. 2015;136(737\u201346):e4.","journal-title":"J Allergy Clin Immunol"},{"key":"791_CR32","doi-asserted-by":"publisher","first-page":"e1341367","DOI":"10.1080\/21688370.2017.1341367","volume":"5","author":"KL Pothoven","year":"2017","unstructured":"Pothoven KL, Schleimer RP. The barrier hypothesis and Oncostatin M: restoration of epithelial barrier function as a novel therapeutic strategy for the treatment of type 2 inflammatory disease. Tissue Barriers. 2017;5:e1341367.","journal-title":"Tissue Barriers"},{"key":"791_CR33","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1038\/nri3766","volume":"14","author":"S Rutz","year":"2014","unstructured":"Rutz S, Wang X, Ouyang W. The IL-20 subfamily of cytokines: from host defence to tissue homeostasis. Nat Rev Immunol. 2014;14:783\u201395.","journal-title":"Nat Rev Immunol"},{"key":"791_CR34","doi-asserted-by":"publisher","first-page":"2779","DOI":"10.1002\/eji.200939473","volume":"39","author":"M Tohyama","year":"2009","unstructured":"Tohyama M, Hanakawa Y, Shirakata Y, Dai X, Yang L, Hirakawa S, et al. IL-17 and IL-22 mediate IL-20 subfamily cytokine production in cultured keratinocytes via increased IL-22 receptor expression. Eur J Immunol. 2009;39:2779\u201388.","journal-title":"Eur J Immunol"},{"key":"791_CR35","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1111\/1523-1747.ep12484041","volume":"97","author":"P Madsen","year":"1991","unstructured":"Madsen P, Rasmussen HH, Leffers H, Honore B, Dejgaard K, Olsen E, et al. Molecular cloning, occurrence, and expression of a novel partially secreted protein \u201cpsoriasin\u201d that is highly up-regulated in psoriatic skin. J Invest Dermatol. 1991;97:701\u201312.","journal-title":"J Invest Dermatol"},{"key":"791_CR36","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1111\/1523-1747.ep12395202","volume":"103","author":"HJ Hoffmann","year":"1994","unstructured":"Hoffmann HJ, Olsen E, Etzerodt M, Madsen P, Thogersen HC, Kruse T, et al. Psoriasin binds calcium and is upregulated by calcium to levels that resemble those observed in normal skin. J Invest Dermatol. 1994;103:370\u20135.","journal-title":"J Invest Dermatol"},{"key":"791_CR37","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1471-5945-3-1","volume":"3","author":"S Alowami","year":"2003","unstructured":"Alowami S, Qing G, Emberley E, Snell L, Watson PH. Psoriasin (S100A7) expression is altered during skin tumorigenesis. BMC Dermatol. 2003;3:1.","journal-title":"BMC Dermatol"},{"key":"791_CR38","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1002\/(SICI)1522-2683(19990201)20:2<349::AID-ELPS349>3.0.CO;2-B","volume":"20","author":"M Ostergaard","year":"1999","unstructured":"Ostergaard M, Wolf H, Orntoft TF, Celis JE. Psoriasin (S100A7): a putative urinary marker for the follow-up of patients with bladder squamous cell carcinomas. Electrophoresis. 1999;20:349\u201354.","journal-title":"Electrophoresis"},{"key":"791_CR39","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.1111\/bjd.14718","volume":"175","author":"J Vegfors","year":"2016","unstructured":"Vegfors J, Ekman AK, Stoll SW, Bivik Eding C, Enerback C. Psoriasin (S100A7) promotes stress-induced angiogenesis. Br J Dermatol. 2016;175:1263\u201373.","journal-title":"Br J Dermatol"},{"key":"791_CR40","doi-asserted-by":"publisher","first-page":"48","DOI":"10.4161\/19336918.2014.987587","volume":"9","author":"SP Giblin","year":"2015","unstructured":"Giblin SP, Midwood KS. Tenascin-C: form versus function. Cell Adh Migr. 2015;9:48\u201382.","journal-title":"Cell Adh Migr"},{"key":"791_CR41","doi-asserted-by":"publisher","first-page":"11703","DOI":"10.1038\/ncomms11703","volume":"7","author":"S Bhattacharyya","year":"2016","unstructured":"Bhattacharyya S, Wang W, Morales-Nebreda L, Feng G, Wu M, Zhou X, et al. Tenascin-C drives persistence of organ fibrosis. Nat Commun. 2016;7:11703.","journal-title":"Nat Commun"},{"key":"791_CR42","doi-asserted-by":"publisher","first-page":"748","DOI":"10.1016\/j.exer.2010.08.025","volume":"91","author":"K Ohtomo","year":"2010","unstructured":"Ohtomo K, Ebihara N, Matsuda A, Tokura T, Funaki T, Murakami A. Role of TGF-beta in tissue eosinophilia associated with vernal keratoconjunctivitis. Exp Eye Res. 2010;91:748\u201354.","journal-title":"Exp Eye Res"}],"container-title":["Japanese Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10384-020-00791-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10384-020-00791-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10384-020-00791-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T16:07:24Z","timestamp":1674835644000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10384-020-00791-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["791"],"URL":"https:\/\/doi.org\/10.1007\/s10384-020-00791-8","relation":{},"ISSN":["0021-5155","1613-2246"],"issn-type":[{"value":"0021-5155","type":"print"},{"value":"1613-2246","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"31 January 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 September 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 January 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"K. Mashimo, None; A. Usui-Ouchi, None; Y. Ito, None; R. Wakasa-Arai, None; N. Yokoi, None; S. Kawasaki, None; A. Murakami, None; A. Matsuda, None; N. Ebihara, None.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}