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Ueno, Patent License Fee (Aurion Biotechnologies, CorneaGen), Honorarium for consulting (Aurion Biotechnologies), Honorarium for lecture (Kowa), Stock (Aurion Biotechnologies); K. Imai, Honorarium for consulting (Aurion Biotechnologies); Y. Tomioka, None; G. Horiguchi, None; T. Kameda, None; S. Teramukai, Payment or honoraria for Statistical Advisor (Daiichi-Sankyo, AtWorking, Sanofi, Chugai); A. Tsujikawa, None; T. Inatomi, None; C. Sotozono, Grant to the author\u2019s institution (Santen, Sun Contact Lens, CorneaGen), Honorarium for consulting (Aurion Biotechnologies),\u00a0Payment or honoraria for lectures (Otsuka, Senju, Santen, Kowa, Nitto medic); S. 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