{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:42:56Z","timestamp":1787503376283,"version":"build-2736575974"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T00:00:00Z","timestamp":1758844800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T00:00:00Z","timestamp":1758844800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Jpn J Ophthalmol"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To determine whether a white cataract (WC) with elevated intralenticular pressure (EWC) can be distinguished from one with normal intralenticular pressure (NWC) using an optical biometer based on Swept-Source Optical Coherence Tomography (SS-OCT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study design<\/jats:title>\n                    <jats:p>Retrospective observational study<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients with a WC who had undergone phacoemulsification and intraocular lens (IOL) implantation at Iwate Medical University Hospital were enrolled. Using surgical videos, WCs with\/without leakage of the liquefied cortex or bulging of the swollen cortex were classified as EWC and NWC, respectively. Both groups were compared in terms of age, sex, ocular comorbidities, various parameters, and the presence of characteristic appearances of the liquefied cortex on SS-OCT images. If the parameters were not measured appropriately, remeasurement using SS-OCT images were performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 48 patients with a WC, 26 eyes were classified as having an EWC, and 22 as NWC. There were significant differences in lens thickness (LT), anterior chamber depth (ACD), \u0394LT, \u0394ACD (the differences in LT or ACD between the eyes with a WC and the fellow eyes, respectively), and age between an EWC and an NWC. ROC analysis showed that the AUC values of LT, \u0394LT, and \u0394ACD were higher than 0.970. LT required remeasurement in approximately half of the WC, whereas ACD did not. Image evaluation for detecting an EWC had a sensitivity of 88.5% and a specificity of 90.9%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>An optical biometer based on SS-OCT may detect an EWC using LT, \u0394LT, \u0394ACD, and SS-OCT images.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10384-025-01284-2","type":"journal-article","created":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T07:34:13Z","timestamp":1758872053000},"page":"296-303","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Detection of a white cataract with elevated intralenticular pressure using an optical biometer based on swept-source optical coherence tomography"],"prefix":"10.1007","volume":"70","author":[{"given":"Shota","family":"Kamei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kouhei","family":"Hashizume","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junya","family":"Kizawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daijiro","family":"Kurosaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,9,26]]},"reference":[{"key":"1284_CR1","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1097\/j.jcrs.0000000000001051","volume":"49","author":"RH Osher","year":"2023","unstructured":"Osher RH. Pearls for the young cataract surgeon: the white cataract. J Cataract Refract Surg. 2023;49:3\u20134.","journal-title":"J Cataract Refract Surg"},{"key":"1284_CR2","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1097\/j.jcrs.0000000000000086","volume":"46","author":"JS Titiyal","year":"2020","unstructured":"Titiyal JS, Kaur M, Shaikh F, Goel S, Bageshwar LMS. Real-time intraoperative dynamics of white cataract-intraoperative optical coherence tomography-guided classification and management. J Cataract Refract Surg. 2020;46:598\u2013605.","journal-title":"J Cataract Refract Surg"},{"key":"1284_CR3","doi-asserted-by":"publisher","first-page":"2178","DOI":"10.1016\/S0161-6420(99)90502-X","volume":"106","author":"PD Brazitikos","year":"1999","unstructured":"Brazitikos PD, Tsinopoulos IT, Papadopoulos NT, Fotiadis K, Stangos NT. Ultrasonographic classification and phacoemulsification of white senile cataracts. Ophthalmology. 1999;106:2178\u201383.","journal-title":"Ophthalmology"},{"key":"1284_CR4","doi-asserted-by":"publisher","first-page":"1356","DOI":"10.1136\/bjo.87.11.1356","volume":"87","author":"SS Ermis\u015f","year":"2003","unstructured":"Ermis\u015f SS, Ozt\u00fcrk F, Inan UU. Comparing the efficacy and safety of phacoemulsification in white mature and other types of senile cataracts. Br J Ophthalmol. 2003;87:1356\u20139.","journal-title":"Br J Ophthalmol"},{"key":"1284_CR5","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1016\/j.jcrs.2018.11.009","volume":"45","author":"A Dhami","year":"2019","unstructured":"Dhami A, Dhami AS, Singh H, Dhami GS. Role of anterior segment optical coherence tomography for safer management of mature white cataracts. J Cataract Refract Surg. 2019;45:480\u20134.","journal-title":"J Cataract Refract Surg"},{"key":"1284_CR6","doi-asserted-by":"publisher","first-page":"1819","DOI":"10.1016\/S0886-3350(01)01316-5","volume":"28","author":"S Jacob","year":"2002","unstructured":"Jacob S, Agarwal A, Agarwal A, Agarwal S, Chowdhary S, Chowdhary R, et al. Trypan blue as an adjunct for safe phacoemulsification in eyes with white cataract. J Cataract Refract Surg. 2002;28:1819\u201325.","journal-title":"J Cataract Refract Surg"},{"key":"1284_CR7","doi-asserted-by":"publisher","first-page":"1531","DOI":"10.1016\/j.jcrs.2012.07.002","volume":"38","author":"CG Figueiredo","year":"2012","unstructured":"Figueiredo CG, Figueiredo J, Figueiredo GB. Brazilian technique for prevention of the Argentinean flag sign in white cataract. J Cataract Refract Surg. 2012;38:1531\u20136.","journal-title":"J Cataract Refract Surg"},{"key":"1284_CR8","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1016\/S0886-3350(13)80739-0","volume":"16","author":"HV Gimbel","year":"1990","unstructured":"Gimbel HV. Two-stage capsulorhexis for endocapsular phacoemulsification. J Cataract Refract Surg. 1990;16:246\u20139.","journal-title":"J Cataract Refract Surg"},{"key":"1284_CR9","doi-asserted-by":"publisher","first-page":"162","DOI":"10.4103\/IJO.IJO_1418_23","volume":"72","author":"SA LoBue","year":"2024","unstructured":"LoBue SA, Rizzuti AE, Martin CR, Albear SA, Gill ES, Shelby CL, et al. Preventing the Argentinian flag sign and managing anterior capsular tears: a review. Indian J Ophthalmol. 2024;72:162\u201373.","journal-title":"Indian J Ophthalmol"},{"key":"1284_CR10","first-page":"1317","volume":"11","author":"L Wang","year":"2018","unstructured":"Wang L, Li P, Guo X. Comparison of diathermic high-frequency capsulorhexis and continuous curvilinear capsulorrhexis in white cataract surgery. Int J Ophthalmol. 2018;11:1317\u201321.","journal-title":"Int J Ophthalmol"},{"key":"1284_CR11","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1016\/j.jcrs.2013.08.044","volume":"40","author":"I Conrad-Hengerer","year":"2014","unstructured":"Conrad-Hengerer I, Hengerer FH, Joachim SC, Schultz T, Dick HB. Femtosecond laser-assisted cataract surgery in intumescent white cataracts. J Cataract Refract Surg. 2014;40:44\u201350.","journal-title":"J Cataract Refract Surg"},{"key":"1284_CR12","doi-asserted-by":"publisher","first-page":"2099","DOI":"10.4103\/ijo.IJO_1650_19","volume":"68","author":"A Pujari","year":"2020","unstructured":"Pujari A, Selvan H, Urkude J, Singh R, Mukhija R, Yadav S, et al. Intralenticular changes in eyes with mature senile cataract on modified posterior segment optical coherence tomography. Indian J Ophthalmol. 2020;68:2099\u2013102.","journal-title":"Indian J Ophthalmol"},{"key":"1284_CR13","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1046\/j.1440-1606.1999.00150.x","volume":"27","author":"S Basti","year":"1999","unstructured":"Basti S. Different faces of the white cataract: a phaco surgeon\u2019s perspective. Aust N Z J Ophthalmol. 1999;27:53\u20136.","journal-title":"Aust N Z J Ophthalmol"},{"key":"1284_CR14","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e34873","volume":"10","author":"W Zhang","year":"2024","unstructured":"Zhang W, Liao M, Tang Q. Parameters influencing the effectiveness of femtosecond laser-assisted capsulotomy in white cataract surgery. Heliyon. 2024;10:e34873.","journal-title":"Heliyon"},{"key":"1284_CR15","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2024.104043","volume":"46","author":"G Toprak","year":"2024","unstructured":"Toprak G, Alkan Y, Bayrak A. Preoperative evaluation of white cataracts with the pentacam. Photodiagnosis Photodyn Ther. 2024;46:104043.","journal-title":"Photodiagnosis Photodyn Ther"},{"key":"1284_CR16","doi-asserted-by":"publisher","first-page":"1398","DOI":"10.4103\/ijo.IJO_1903_20","volume":"69","author":"M Balyan","year":"2021","unstructured":"Balyan M, Jain AK, Malhotra C, Ram J, Dhingra D. Achieving successful capsulorhexis in intumescent white mature cataracts to prevent Argentinian flag sign \u2013 a new multifaceted approach to meet the challenge. Indian J Ophthalmol. 2021;69:1398\u2013403.","journal-title":"Indian J Ophthalmol"},{"key":"1284_CR17","doi-asserted-by":"publisher","first-page":"389","DOI":"10.2147\/OPTH.S286996","volume":"15","author":"A Pujari","year":"2021","unstructured":"Pujari A, Sharma N. The emerging role of anterior segment optical coherence tomography in cataract surgery: current role and future perspectives. Clin Ophthalmol. 2021;15:389\u2013401.","journal-title":"Clin Ophthalmol"},{"key":"1284_CR18","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1167\/iovs.07-1216","volume":"50","author":"Y Zeng","year":"2009","unstructured":"Zeng Y, Liu Y, Liu X, Chen C, Xia Y, Lu M, et al. Comparison of lens thickness measurements using the anterior segment optical coherence tomography and A-scan ultrasonography. Invest Ophthalmol Vis Sci. 2009;50:290\u20134.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1284_CR19","doi-asserted-by":"publisher","first-page":"1191","DOI":"10.2147\/OPTH.S464538","volume":"18","author":"M Pathak","year":"2024","unstructured":"Pathak M, Sahu V, Kumar A, Kaur K, Gurnani B. Current concepts and recent updates of optical biometry- a comprehensive review. Clin Ophthalmol. 2024;18:1191\u2013206.","journal-title":"Clin Ophthalmol"},{"key":"1284_CR20","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1097\/j.jcrs.0000000000000551","volume":"47","author":"R Mont\u00e9s-Mic\u00f3","year":"2021","unstructured":"Mont\u00e9s-Mic\u00f3 R, Pastor-Pascual F, Ruiz-Mesa R, Ta\u00f1\u00e1-Rivero P. Ocular biometry with swept-source optical coherence tomography. J Cataract Refract Surg. 2021;47:802\u201314.","journal-title":"J Cataract Refract Surg"},{"key":"1284_CR21","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1186\/s12886-021-01932-4","volume":"21","author":"Q Lei","year":"2021","unstructured":"Lei Q, Tu H, Feng X, Ortega-Usobiaga J, Cao D, Wang Y. Distribution of ocular biometric parameters and optimal model of anterior chamber depth regression in 28,709 adult cataract patients in China using swept-source optical biometry. BMC Ophthalmol. 2021;21:178.","journal-title":"BMC Ophthalmol"},{"key":"1284_CR22","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1007\/s10792-021-02020-8","volume":"42","author":"C Albarr\u00e1n-Diego","year":"2022","unstructured":"Albarr\u00e1n-Diego C, Poyales F, L\u00f3pez-Artero E, Garz\u00f3n N, Garc\u00eda-Montero M. Interocular biometric parameters comparison measured with swept-source technology. Int Ophthalmol. 2022;42:239\u201351.","journal-title":"Int Ophthalmol"},{"key":"1284_CR23","doi-asserted-by":"publisher","DOI":"10.1177\/20503121241282956","volume":"12","author":"A Sharifi","year":"2024","unstructured":"Sharifi A, Zand A, Shafiei M, Nasiri N, Sharifi H, Najafzadeh MJ, et al. The influence of age and gender on ocular biometrics and corneal astigmatism in adults undergoing cataract surgery. SAGE Open Med. 2024;12:20503121241282956.","journal-title":"SAGE Open Med"},{"key":"1284_CR24","doi-asserted-by":"publisher","first-page":"179","DOI":"10.3109\/03091902.2014.899401","volume":"38","author":"Y Li","year":"2014","unstructured":"Li Y, Bao FJ. Interocular symmetry analysis of bilateral eyes. J Med Eng Technol. 2014;38:179\u201387.","journal-title":"J Med Eng Technol"},{"key":"1284_CR25","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0269709","volume":"17","author":"A Langenbucher","year":"2022","unstructured":"Langenbucher A, Szentm\u00e1ry N, Cayless A, R\u00f6ggla V, Leydolt C, Wendelstein J, et al. Similarity of eyes in a cataractous population-how reliable is the biometry of the fellow eye for lens power calculation? PLoS ONE. 2022;17:e0269709.","journal-title":"PLoS ONE"},{"key":"1284_CR26","doi-asserted-by":"publisher","first-page":"1591","DOI":"10.18240\/ijo.2022.10.05","volume":"15","author":"Y-H Wang","year":"2022","unstructured":"Wang Y-H, Zhong J, Li X-M. Age-related changes of lens thickness and density in different age phases. Int J Ophthalmol. 2022;15:1591\u20137.","journal-title":"Int J Ophthalmol"},{"key":"1284_CR27","doi-asserted-by":"publisher","first-page":"351","DOI":"10.2147\/OPTH.S446031","volume":"18","author":"T Tanaka","year":"2024","unstructured":"Tanaka T, Nishitsuka K, Obata H. Correlation of ocular biometry with axial length in elderly Japanese. Clin Ophthalmol. 2024;18:351\u201360.","journal-title":"Clin Ophthalmol"}],"container-title":["Japanese Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10384-025-01284-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10384-025-01284-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10384-025-01284-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T05:40:12Z","timestamp":1776490812000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10384-025-01284-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,26]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["1284"],"URL":"https:\/\/doi.org\/10.1007\/s10384-025-01284-2","relation":{},"ISSN":["0021-5155","1613-2246"],"issn-type":[{"value":"0021-5155","type":"print"},{"value":"1613-2246","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,26]]},"assertion":[{"value":"24 April 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 August 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 September 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"S. Kamei, None; K. Hashizume, None; J. Kizawa, None; D. Kurosaka, None.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}