{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T14:29:22Z","timestamp":1761920962428,"version":"3.37.3"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2021,11,20]],"date-time":"2021-11-20T00:00:00Z","timestamp":1637366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,11,20]],"date-time":"2021-11-20T00:00:00Z","timestamp":1637366400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001809","name":"national natural science foundation of china","doi-asserted-by":"publisher","award":["81800478","81900237"],"award-info":[{"award-number":["81800478","81900237"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004608","name":"natural science foundation of jiangsu province","doi-asserted-by":"publisher","award":["BK20181082","BK20191093"],"award-info":[{"award-number":["BK20181082","BK20191093"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Esophagus"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1007\/s10388-021-00895-1","type":"journal-article","created":{"date-parts":[[2021,11,20]],"date-time":"2021-11-20T12:02:42Z","timestamp":1637409762000},"page":"343-350","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Protective effect of rosuvastatin against the formation of benign esophageal stricture"],"prefix":"10.1007","volume":"19","author":[{"given":"Boqian","family":"Zhu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bingzhan","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanjuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meiling","family":"Bao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenfang","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weifeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meihong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8135-5310","authenticated-orcid":false,"given":"Yaoyao","family":"Gong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,11,20]]},"reference":[{"key":"895_CR1","doi-asserted-by":"crossref","unstructured":"de Wijkerslooth LR, Vleggaar FP, Siersema PD. Endoscopic management of difficult or recurrent esophageal strictures. Am J Gastroenterol 2011, 106(12):2080\u20132091; quiz 2092.","DOI":"10.1038\/ajg.2011.348"},{"issue":"11","key":"895_CR2","doi-asserted-by":"publisher","first-page":"E1698","DOI":"10.1055\/a-1261-3103","volume":"8","author":"J Martinek","year":"2020","unstructured":"Martinek J, Dolezel R, Walterova B, et al. Stenting to prevent esophageal stricture after circumferential endoscopic submucosal dissection: an experimental study. Endosc Int Open. 2020;8(11):E1698\u2013706.","journal-title":"Endosc Int Open"},{"issue":"23","key":"895_CR3","doi-asserted-by":"publisher","first-page":"7120","DOI":"10.3748\/wjg.v21.i23.7120","volume":"21","author":"K Uno","year":"2015","unstructured":"Uno K, Iijima K, Koike T, et al. Useful strategies to prevent severe stricture after endoscopic submucosal dissection for superficial esophageal neoplasm. World J Gastroenterol. 2015;21(23):7120\u201333.","journal-title":"World J Gastroenterol"},{"issue":"1","key":"895_CR4","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1111\/wrr.12136","volume":"22","author":"JH Mun","year":"2014","unstructured":"Mun JH, Kim YM, Kim BS, et al. Simvastatin inhibits transforming growth factor-beta1-induced expression of type I collagen, CTGF, and alpha-SMA in keloid fibroblasts. Wound Repair Regen. 2014;22(1):125\u201333.","journal-title":"Wound Repair Regen"},{"issue":"18 Pt 1","key":"895_CR5","doi-asserted-by":"publisher","first-page":"5331","DOI":"10.1158\/1078-0432.CCR-07-0625","volume":"13","author":"V Haydont","year":"2007","unstructured":"Haydont V, Bourgier C, Pocard M, et al. Pravastatin Inhibits the Rho\/CCN2\/extracellular matrix cascade in human fibrosis explants and improves radiation-induced intestinal fibrosis in rats. Clin Cancer Res. 2007;13(18 Pt 1):5331\u201340.","journal-title":"Clin Cancer Res"},{"issue":"2","key":"895_CR6","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1007\/s10620-011-1879-4","volume":"57","author":"Y Abe","year":"2012","unstructured":"Abe Y, Murano M, Murano N, et al. Simvastatin attenuates intestinal fibrosis independent of the anti-inflammatory effect by promoting fibroblast\/myofibroblast apoptosis in the regeneration\/healing process from TNBS-induced colitis. Dig Dis Sci. 2012;57(2):335\u201344.","journal-title":"Dig Dis Sci"},{"key":"895_CR7","doi-asserted-by":"crossref","unstructured":"Mohanty A, Tate JP, Garcia-Tsao G. Statins Are Associated With a Decreased Risk of Decompensation and Death in Veterans With Hepatitis C-Related Compensated Cirrhosis. Gastroenterology 2016, 150(2):430\u2013440 e431.","DOI":"10.1053\/j.gastro.2015.10.007"},{"issue":"28","key":"895_CR8","doi-asserted-by":"publisher","first-page":"8629","DOI":"10.3748\/wjg.v21.i28.8629","volume":"21","author":"J Liu","year":"2015","unstructured":"Liu J, Shang L, Liu JY, et al. Newly designed \u201cpieced\u201d stent in a rabbit model of benign esophageal stricture. World J Gastroenterol. 2015;21(28):8629\u201335.","journal-title":"World J Gastroenterol"},{"issue":"8","key":"895_CR9","doi-asserted-by":"publisher","first-page":"1474","DOI":"10.1016\/j.jpedsurg.2007.10.001","volume":"43","author":"A Guven","year":"2008","unstructured":"Guven A, Demirbag S, Uysal B, et al. Effect of 3-amino benzamide, a poly(adenosine diphosphate-ribose) polymerase inhibitor, in experimental caustic esophageal burn. J Pediatr Surg. 2008;43(8):1474\u20139.","journal-title":"J Pediatr Surg"},{"issue":"1","key":"895_CR10","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1053\/j.gastro.2018.11.040","volume":"156","author":"PD Siersema","year":"2019","unstructured":"Siersema PD. How to approach a patient with refractory or recurrent benign esophageal stricture. Gastroenterology. 2019;156(1):7\u201310.","journal-title":"Gastroenterology"},{"issue":"6","key":"895_CR11","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/dote\/dox029","volume":"30","author":"P Le Naoures","year":"2017","unstructured":"Le Naoures P, Hamy A, Lerolle N, et al. Risk factors for symptomatic esophageal stricture after caustic ingestion-a retrospective cohort study. Dis Esophagus. 2017;30(6):1\u20136.","journal-title":"Dis Esophagus"},{"issue":"3","key":"895_CR12","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1097\/MCG.0b013e3181f39f4e","volume":"45","author":"Y Ezoe","year":"2011","unstructured":"Ezoe Y, Muto M, Horimatsu T, et al. Efficacy of preventive endoscopic balloon dilation for esophageal stricture after endoscopic resection. J Clin Gastroenterol. 2011;45(3):222\u20137.","journal-title":"J Clin Gastroenterol"},{"issue":"6","key":"895_CR13","doi-asserted-by":"publisher","first-page":"E771","DOI":"10.1055\/a-0889-8010","volume":"7","author":"J Martinek","year":"2019","unstructured":"Martinek J. How to prevent post-ESD esophageal stricture. Endosc Int Open. 2019;7(6):E771\u20133.","journal-title":"Endosc Int Open"},{"key":"895_CR14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12876-014-0226-6","volume":"15","author":"H Takahashi","year":"2015","unstructured":"Takahashi H, Arimura Y, Okahara S, et al. A randomized controlled trial of endoscopic steroid injection for prophylaxis of esophageal stenoses after extensive endoscopic submucosal dissection. BMC Gastroenterol. 2015;15:1.","journal-title":"BMC Gastroenterol"},{"key":"895_CR15","doi-asserted-by":"crossref","unstructured":"Hirdes MM, van Hooft JE, Koornstra JJ et al. Endoscopic corticosteroid injections do not reduce dysphagia after endoscopic dilation therapy in patients with benign esophagogastric anastomotic strictures. Clin Gastroenterol Hepatol 2013, 11(7):795\u2013801 e791.","DOI":"10.1016\/j.cgh.2013.01.016"},{"issue":"6","key":"895_CR16","doi-asserted-by":"publisher","first-page":"E764","DOI":"10.1055\/a-0894-4374","volume":"7","author":"S Hashimoto","year":"2019","unstructured":"Hashimoto S, Mizuno KI, Takahashi K, et al. Evaluating the effect of injecting triamcinolone acetonide in two sessions for preventing esophageal stricture after endoscopic submucosal dissection. Endosc Int Open. 2019;7(6):E764\u201370.","journal-title":"Endosc Int Open"},{"issue":"9","key":"895_CR17","doi-asserted-by":"publisher","first-page":"1058","DOI":"10.1016\/j.dld.2016.06.024","volume":"48","author":"MJ Bartel","year":"2016","unstructured":"Bartel MJ, Seeger K, Jeffers K, et al. Topical Mitomycin C application in the treatment of refractory benign esophageal strictures in adults and comprehensive literature review. Dig Liver Dis. 2016;48(9):1058\u201365.","journal-title":"Dig Liver Dis"},{"issue":"1","key":"895_CR18","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1093\/cvr\/cvt070","volume":"99","author":"N Hermida","year":"2013","unstructured":"Hermida N, Markl A, Hamelet J, et al. HMGCoA reductase inhibition reverses myocardial fibrosis and diastolic dysfunction through AMP-activated protein kinase activation in a mouse model of metabolic syndrome. Cardiovasc Res. 2013;99(1):44\u201354.","journal-title":"Cardiovasc Res"},{"issue":"3","key":"895_CR19","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1016\/j.cardiores.2004.07.020","volume":"64","author":"KE Porter","year":"2004","unstructured":"Porter KE, Turner NA, O\u2019Regan DJ, et al. Tumor necrosis factor alpha induces human atrial myofibroblast proliferation, invasion and MMP-9 secretion: inhibition by simvastatin. Cardiovasc Res. 2004;64(3):507\u201315.","journal-title":"Cardiovasc Res"},{"issue":"2","key":"895_CR20","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/j.yjmcc.2007.05.006","volume":"43","author":"NA Turner","year":"2007","unstructured":"Turner NA, Aley PK, Hall KT, et al. Simvastatin inhibits TNFalpha-induced invasion of human cardiac myofibroblasts via both MMP-9-dependent and -independent mechanisms. J Mol Cell Cardiol. 2007;43(2):168\u201376.","journal-title":"J Mol Cell Cardiol"}],"container-title":["Esophagus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10388-021-00895-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10388-021-00895-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10388-021-00895-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T03:08:53Z","timestamp":1647313733000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10388-021-00895-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,20]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["895"],"URL":"https:\/\/doi.org\/10.1007\/s10388-021-00895-1","relation":{},"ISSN":["1612-9059","1612-9067"],"issn-type":[{"type":"print","value":"1612-9059"},{"type":"electronic","value":"1612-9067"}],"subject":[],"published":{"date-parts":[[2021,11,20]]},"assertion":[{"value":"22 July 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 November 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 November 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All animal experimental protocols were approved by the Institutional Animal and Use Committee of Nanjing Medical University. All institutional and national guidelines for the care and use of laboratory animals were followed.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Statement"}},{"value":"Boqian Zhu, Bingzhan Song, Yanjuan Wang, Meiling Bao, Wenfang Cheng, Weifeng Zhang, Meihong Liu, and Yaoyao Gong declare that they have no conflict of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}