{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T20:06:24Z","timestamp":1648670784230},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[1999,7,1]],"date-time":"1999-07-01T00:00:00Z","timestamp":930787200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Surg Oncol"],"published-print":{"date-parts":[[1999,7]]},"DOI":"10.1007\/s10434-999-0476-7","type":"journal-article","created":{"date-parts":[[2005,2,25]],"date-time":"2005-02-25T23:52:24Z","timestamp":1109375544000},"page":"476-480","source":"Crossref","is-referenced-by-count":4,"title":["Thrombocytopenia After Isolated Limb or Hepatic Perfusions with Melphalan: The Risk of Heparin-Induced Thrombocytopenia"],"prefix":"10.1007","volume":"6","author":[{"given":"Iris P.","family":"Masucci","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karim A.","family":"Calis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David L.","family":"Bartlett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. Richard","family":"Alexander","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"III","given":"McDonald K.","family":"Horne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"476_CR1","first-page":"171","volume-title":"Cutaneous Melanoma","author":"ET Krementz","year":"1985","unstructured":"Krementz ET, Ryan RF, Carter RD, Sutherland CM, Reed RJ. Hyperthermic regional perfusion for melanoma of the limbs. In: Balch CM, Milton GW, eds. Cutaneous Melanoma. Philadelphia: JB Lippincott, 1985:171\u2013195."},{"key":"476_CR2","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1200\/JCO.1992.10.1.52","volume":"10","author":"D Lienard","year":"1992","unstructured":"Lienard D, Ewalenko P, Delmotte J-J, Renard N, Lejeune FJ. High-dose recombinant tumor necrosis factor alpha in combination with interferon gamma and melphalan in isolation perfusion of the limbs for melanoma and sarcoma. J Clin Oncol 1992;10:52\u201360.","journal-title":"J Clin Oncol"},{"key":"476_CR3","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1002\/(SICI)1098-2388(199611\/12)12:6<416::AID-SSU7>3.0.CO;2-D","volume":"12","author":"HR Alexander","year":"1996","unstructured":"Alexander HR, Fraker DL, Bartlett DL. Isolated limb perfusion for malignant melanoma. Semin Surg Oncol 1996;12:416.","journal-title":"Semin Surg Oncol"},{"key":"476_CR4","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1097\/00000658-197509000-00014","volume":"182","author":"CM McBride","year":"1975","unstructured":"McBride CM, Sugarbaker EV, Hickey RC. Prophylactic isolationperfusion as the primary therapy for invasive malignant melanoma of the limbs. Ann Surg 1975;182:316\u2013324.","journal-title":"Ann Surg"},{"key":"476_CR5","doi-asserted-by":"publisher","first-page":"1162","DOI":"10.1056\/NEJM198805053181805","volume":"318","author":"R Collins","year":"1988","unstructured":"Collins R, Scrimgeour A, Yusuf S, Peta R. Reduction in fatal pulmonary embolism and venous thrombosis by perioperative administration of subcutaneous heparin. N Engl J Med 1988;318:1162\u20131173.","journal-title":"N Engl J Med"},{"key":"476_CR6","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1097\/00000441-199304000-00003","volume":"305","author":"BP Schmitt","year":"1993","unstructured":"Schmitt BP, Adelman B. Heparin-associated thrombocytopenia: a critical review and pooled analysis. Am J Med Sci 1993;305:208\u2013215. 264\u2013273.","journal-title":"Am J Med Sci"},{"key":"476_CR7","doi-asserted-by":"crossref","first-page":"535","DOI":"10.7326\/0003-4819-100-4-535","volume":"100","author":"DJ King","year":"1984","unstructured":"King DJ, Kelton JG. Heparin-associated thrombocytopenia. Ann Intern Med 1984;100:535\u2013540.","journal-title":"Ann Intern Med"},{"key":"476_CR8","doi-asserted-by":"publisher","first-page":"502","DOI":"10.1016\/S0002-9343(96)00258-6","volume":"101","author":"TE Warkentin","year":"1996","unstructured":"Warkentin TE, Kelton JG. A 14-year study of heparin-induced thrombocytopenia. Am J Med 1996;101:502\u2013507.","journal-title":"Am J Med"},{"key":"476_CR9","first-page":"2","volume":"4","author":"HR Alexander","year":"1998","unstructured":"Alexander HR, Bartlett DL, Libutti SK. Isolated hepatic perfusion: a potentially effective treatment for patients with metastatic or primary cancers confined to the liver. Cancer J 1998;4:2\u201311.","journal-title":"Cancer J"},{"key":"476_CR10","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/S0022-2143(96)90060-8","volume":"127","author":"MK Horne","year":"1996","unstructured":"Horne MK, Alkins BR. Platelet binding of IgG from patients with heparin-induced thrombocytopenia. J Lab Clin Med 1996;127:435\u2013442.","journal-title":"J Lab Clin Med"},{"key":"476_CR11","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1182\/blood.V67.1.27.27","volume":"67","author":"D Sheridan","year":"1986","unstructured":"Sheridan D, Carter C, Kelton JG. A diagnostic test for heparininduced thrombocytopenia. Blood 1986;67:27\u201330.","journal-title":"Blood"},{"key":"476_CR12","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1093\/ajcp\/104.6.648","volume":"104","author":"G Arepally","year":"1995","unstructured":"Arepally G, Reynolds C, Tomaski A, Amiral J, Jawad A, Poncz M, Cines DB. Comparison of PF4\/heparin ELISA assay with the 14C-serotonin release assay in the diagnosis of heparin-induced thrombocytopenia. Am J Clin Pathol 1995;104:648\u2013652.","journal-title":"Am J Clin Pathol"},{"key":"476_CR13","first-page":"1275","volume-title":"Hemostasis and Thrombosis: Basic Principles and Clinical Practice","author":"EW Salzman","year":"1994","unstructured":"Salzman EW, Hirsh J. The epidemiology, pathogenesis, and natural history of venous thrombosis. In: Colman RW, Hirsh J, Marder VJ, Salzman EW, eds. Hemostasis and Thrombosis: Basic Principles and Clinical Practice. 3rd edn. Philadelphia: JB Lippincott, 1994:1275\u20131296.","edition":"3"},{"key":"476_CR14","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/S0022-5223(19)34841-X","volume":"104","author":"SF Khuri","year":"1992","unstructured":"Khuri SF, Wolfe JA, Josa M, et al. Hematologic changes during and after cardiopulmonary bypass and their relationship to the bleeding time and nonsurgical blood loss. J Thorac Cardiovasc Surg 1992;104:94\u2013107.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"476_CR15","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1200\/JCO.1995.13.1.264","volume":"13","author":"AK Thom","year":"1995","unstructured":"Thom AK, Alexander HR, Andrich MP, Barker WC, Rosenberg SA, Fraker DL. Cytokine levels and systemic toxicity in patients undergoing isolated limb perfusion with high-dose tumor necrosis factor, interferon gamma, and melphalan. J Clin Oncol 1995;13:264\u2013273.","journal-title":"J Clin Oncol"},{"key":"476_CR16","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/S0022-2143(96)80009-6","volume":"128","author":"GP Visentin","year":"1996","unstructured":"Visentin GP, Malik M, Cyganiak KA, Aster RH. Patients treated with unfractionated heparin during open heart surgery are at high risk to form antibodies reactive with heparin:platelet factor 4 complexes. J Lab Clin Med 1996;128:376\u2013383.","journal-title":"J Lab Clin Med"},{"key":"476_CR17","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1161\/01.CIR.95.5.1242","volume":"95","author":"TL Bauer","year":"1997","unstructured":"Bauer TL, Arepally G, Konkel BA, et al. Prevalence of heparinassociated antibodies without thrombosis in patients undergoing cardiopulmonary bypass surgery. Circulation 1997;95:1242\u20131246.","journal-title":"Circulation"},{"key":"476_CR18","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1046\/j.1365-2141.1998.00750.x","volume":"101","author":"M Trossaert","year":"1998","unstructured":"Trossaert M, Gaillard A, Commin PL, Amiral J, Vissac A-M, Fressinaud E. High incidence of anti-heparin\/platelet factor 4 antibodies after cardiopulmonary bypass surgery. Br J Haematol 1998;101:653\u2013655.","journal-title":"Br J Haematol"},{"key":"476_CR19","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1002\/(SICI)1096-8652(199703)54:3<196::AID-AJH4>3.0.CO;2-R","volume":"54","author":"J-S Suh","year":"1997","unstructured":"Suh J-S, Malik MI, Aster RH, Visentin GP. Characterization of the humoral immune response in heparin-induced thrombocytopenia. Am J Hematol 1997;54:196\u2013201.","journal-title":"Am J Hematol"},{"key":"476_CR20","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1055\/s-0038-1649626","volume":"70","author":"HN Magnani","year":"1993","unstructured":"Magnani HN. Heparin-induced thrombocytopenia (HIT): an overview of 230 patients treated with Orgaran (Org 10172). Thromb Haemost 1993;70:554\u2013560.","journal-title":"Thromb Haemost"},{"issue":"Suppl 1","key":"476_CR21","first-page":"281a","volume":"88","author":"A Greinacher","year":"1996","unstructured":"Greinacher A, Volpel H, Potzsch B. Recombinant hirudin in the treatment of patients with heparin-induced thrombocytopenia (HIT). Blood 1996;88(Suppl 1):281a.","journal-title":"Blood"}],"container-title":["Annals of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10434-999-0476-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10434-999-0476-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10434-999-0476-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10434-999-0476-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,17]],"date-time":"2020-02-17T23:24:41Z","timestamp":1581981881000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10434-999-0476-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,7]]},"references-count":21,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1999,7]]}},"alternative-id":["476"],"URL":"https:\/\/doi.org\/10.1007\/s10434-999-0476-7","relation":{},"ISSN":["1068-9265","1534-4681"],"issn-type":[{"value":"1068-9265","type":"print"},{"value":"1534-4681","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,7]]}}}