{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:18:18Z","timestamp":1760782698842},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[1999,12,1]],"date-time":"1999-12-01T00:00:00Z","timestamp":944006400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Surg Oncol"],"published-print":{"date-parts":[[1999,12]]},"DOI":"10.1007\/s10434-999-0762-4","type":"journal-article","created":{"date-parts":[[2005,2,26]],"date-time":"2005-02-26T01:50:08Z","timestamp":1109382608000},"page":"762-767","source":"Crossref","is-referenced-by-count":27,"title":["Primary Tumor Response to Induction Chemotherapy as a Predictor of Histological Status of Axillary Nodes in Operable Breast Cancer Patients"],"prefix":"10.1007","volume":"6","author":[{"given":"Jeffrey T.","family":"Lenert","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georges","family":"Vlastos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadem Q.","family":"Mirza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David J.","family":"Winchester","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanne M.","family":"Binkley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fred C.","family":"Ames","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Merrick I.","family":"Ross","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barry W.","family":"Feig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelly K.","family":"Hunt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Strom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aman U.","family":"Buzdar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel N.","family":"Hortobagyi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. Eva","family":"Singletary","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","first-page":"297","volume":"4","author":"WS Halsted","year":"1894?1895","unstructured":"Halsted WS. The result of operations for the cure of cancer of the breast performed at the Johns Hopkins Hospital from June 1889 to January 1894. Johns Hopkins Hosp Bull 1894?1895;4:297.","journal-title":"Johns Hopkins Hosp Bull"},{"issue":"3?4","key":"CR2","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/0360-3016(78)90154-2","volume":"4","author":"B Fisher","year":"1978","unstructured":"Fisher B. Adjuvant chemotherapy in breast cancer. Int J Radiat Oncol Biol Phys 1978;4(3?4):295?298.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/S0025-7125(16)31272-X","volume":"61","author":"B Fisher","year":"1977","unstructured":"Fisher B. Adjuvant chemotherapy in the primary management of breast cancer. Med Clin North Am 1977;61:953?165.","journal-title":"Med Clin North Am"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1056\/NEJM198902233200803","volume":"320","author":"EG Mansour","year":"1989","unstructured":"Mansour EG, Gray R, Shatila AH, et al. Efficacy of adjuvant chemotherapy in high-risk node-negative breast cancer: an intergroup study. N Engl J Med 1989;320:485?490.","journal-title":"N Engl J Med"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1056\/NEJM198902233200801","volume":"320","author":"B Fisher","year":"1989","unstructured":"Fisher B, Redmond C, Dimintrov NV, et al. A randomized clinical trial evaluating sequential methotrexate and fluorouracil in the treatment of patients with node-negative breast cancer who have estrogen-receptor negative tumors. N Engl J Med 1989;320:473?478.","journal-title":"N Engl J Med"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1056\/NEJM198902233200802","volume":"320","author":"B Fisher","year":"1989","unstructured":"Fisher B, Costantino J, Redmond C, et al. A randomized clinical trial evaluating tamoxifen in the treatment of patients with nodenegative breast cancer who have estrogen-receptor positive tumors. N Engl J Med 1989;320:479?484.","journal-title":"N Engl J Med"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1056\/NEJM198812293192601","volume":"319","author":"Early Breast Cancer Trialists? Collaborative Group","year":"1988","unstructured":"Early Breast Cancer Trialists? Collaborative Group. Effects of adjuvant tamoxifen and cytotoxic therapy on mortality in early breast cancer: an overview of 61 randomized trials among 28,896 women. N Engl J Med 1988;319:1681?1682.","journal-title":"N Engl J Med"},{"key":"CR8","first-page":"1","volume":"11","author":"NIH Consensus Development Panel. Treatment of early stage breast cancer","year":"1992","unstructured":"NIH Consensus Development Panel. Treatment of early stage breast cancer. J Natl Cancer Inst 1992;11:1?5.","journal-title":"J Natl Cancer Inst"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1056\/NEJM198503143121102","volume":"312","author":"B Fisher","year":"1985","unstructured":"Fisher B, Redmond C, Fisher ER, et al. Ten-year results of a randomized clinical trial comparing radical mastectomy and total mastectomy with or without radiation. N Engl J Med 1985;312:674?681.","journal-title":"N Engl J Med"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1200\/JCO.1991.9.6.988","volume":"9","author":"A Recht","year":"1991","unstructured":"Recht A, Pierce SM, Abner A, et al. Regional nodal failure after conservative surgery and radiotherapy for early-stage breast carcinoma. J Clin Oncol 1991;9:988?996.","journal-title":"J Clin Oncol"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/0360-3016(89)90054-0","volume":"17","author":"B Fowble","year":"1989","unstructured":"Fowble B, Solin LJ, Schultz DJ, Goodman FL. Frequency, sites of relapse, and outcome of regional node failures following conservative surgery and radiation for early breast cancer. Int J Radiat Oncol Biol Phys 1989;17:701?710.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/0360-3016(93)90274-Y","volume":"26","author":"KJ Halverson","year":"1993","unstructured":"Halverson KJ, Taylor ME, Perez CA, et al. Regional nodal management and patterns of failure following conservative surgery and radiation therapy for stage I and II breast cancer. Int J Radiation Oncol Biol Phys 1993;26:593?599.","journal-title":"Int J Radiation Oncol Biol Phys"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1002\/jso.2930500114","volume":"50","author":"M Hladiuk","year":"1992","unstructured":"Hladiuk M, Huchcroft S, Temple W, Schnurr BE. Arm function after axillary dissection for breast cancer: a pilot study to provide parameter estimates. J Surg Oncol 1992;50:47?52.","journal-title":"J Surg Oncol"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"667","DOI":"10.3109\/02841868809091766","volume":"27","author":"N Ryttov","year":"1988","unstructured":"Ryttov N, Holm NV, Wvist N, Blichert-Toft M. Influence of adjuvant irradiation on the development of late arm lymphedema and impaired shoulder mobility after mastectomy for carcinoma of the breast. Acta Oncol 1988;27:667?670.","journal-title":"Acta Oncol"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1038\/bjc.1992.230","volume":"66","author":"D Ivens","year":"1992","unstructured":"Ivens D, Hoe AL, Podd TJ, Hamilton CR, Taylor I, Royle GT. Assessment of morbidity from complete axillary dissection. Br J Cancer 1992;66:136?138.","journal-title":"Br J Cancer"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1002\/1097-0142(19951101)76:9<1491::AID-CNCR2820760902>3.0.CO;2-8","volume":"76","author":"A Recht","year":"1995","unstructured":"Recht A, Houlihan MJ. Axillary lymph nodes and breast Cancer. Cancer 1995;76:1492?1512.","journal-title":"Cancer"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1056\/NEJM199511303332202","volume":"333","author":"Early Breast Cancer Trialists? Collaborative Group","year":"1995","unstructured":"Early Breast Cancer Trialists? Collaborative Group. Effects of radiotherapy and surgery in early breast cancer. N Engl J Med 1995;333:1444?1455.","journal-title":"N Engl J Med"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/0360-3016(88)90088-0","volume":"14","author":"MR Baeza","year":"1988","unstructured":"Baeza MR, Sole J, Leon A, et al. Conservative treatment of breast cancer. Int J Radiat Oncol Biol Phys 1988;14:669?676.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/0360-3016(87)90256-2","volume":"13","author":"G Delouche","year":"1987","unstructured":"Delouche G, Bachelot F, Premont M, Kurtz JM. Conservation treatment of early breast cancer: long term results and complications. Int J Radiat Oncol Biol Phys 1987;13:29?34.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"CR20","first-page":"132","volume-title":"American Society of Clinical Oncology educational book","author":"SE Singletary","year":"1998","unstructured":"Singletary SE. Management of the axilla in early stage breast cancer. In: Perry MC, ed. American Society of Clinical Oncology educational book. Alexandria, VA: American Society of Clinical Oncology, 1998:132?141."},{"key":"CR21","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/S0039-6109(05)70446-1","volume":"76","author":"KK Hunt","year":"1996","unstructured":"Hunt KK, Ames FC, Singletary SE, Buzdar AU, Hortobagyi GN. Locally advanced noninflammatory breast cancer. Surg Clin North Am 1996;76:393?410.","journal-title":"Surg Clin North Am"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"2849","DOI":"10.1002\/1097-0142(19920601)69:11<2849::AID-CNCR2820691134>3.0.CO;2-P","volume":"69","author":"SE Singletary","year":"1992","unstructured":"Singletary SE, McNeese MD, Hortobagyi GN. Feasibility of breast conservation surgery after induction chemotherapy for locally advanced carcinoma. Cancer 1992;69:2849?2852.","journal-title":"Cancer"},{"key":"CR23","unstructured":"Peoples GI, Regan W, Heaton KM, et al. Breast conservation therapy for large primary and locally advanced breast cancers after induction chemotherapy. Ann Surg Oncol (in press)."},{"key":"CR24","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1007\/BF02303476","volume":"5","author":"HM Kuerer","year":"1998","unstructured":"Kuerer HM, Newman LA, Fornage BD, et al. Role of axillary lymph node dissection after tumor downstaging with induction chemotherapy for locally advanced breast cancer. Ann Surg Oncol 1998;5:673?680.","journal-title":"Ann Surg Oncol"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1002\/1097-0142(19840115)53:2<349::AID-CNCR2820530230>3.0.CO;2-B","volume":"53","author":"MP Osborne","year":"1984","unstructured":"Osborne MP, Ormiston N, Harmer CL, McKinna JA, Baker J, Greening WP. Breast conservation in the treatment of early breast Cancer: a 20-year follow-up. Cancer 1984;53:349?355.","journal-title":"Cancer"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1001\/archsurg.1996.01430150079015","volume":"131","author":"B Cady","year":"1996","unstructured":"Cady B, Stone MD, Schuler JG, Thakur R, Wanner MA, Lavin PT. The new era in breast cancer: invasion, size, and nodal involvement dramatically decreasing as a result of mammographic screening. Arch Surg 1996;131:301?308.","journal-title":"Arch Surg"},{"key":"CR27","volume-title":"Diseases of the Breast","author":"C Haagensen","year":"1986","unstructured":"Haagensen C. Diseases of the Breast. 3rd ed. Philadelphia: WB Saunders, 1986.","edition":"3"},{"key":"CR28","unstructured":"Chadha M, Axelrod D. Is axillary dissection always indicated in invasive breast cancer? Oncology 1997;11:1463?1468, 1473?1479."},{"key":"CR29","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1111\/j.1524-4741.1997.tb00208.x","volume":"3","author":"IE Smith","year":"1997","unstructured":"Smith IE. Primary\/neoadjuvant chemotherapy for early breast cancer. Breast J 1997;3:53?56.","journal-title":"Breast J"},{"key":"CR30","first-page":"104A","volume":"18","author":"G Vlastos","year":"1999","unstructured":"Vlastos G, Mirza N, Lenert J, et al. Efficacy of paclitaxel neoadjuvant chemotherapy in tumor downstaging of the axilla in T2?3, N0?1, M0 breast cancer. Proc Am Soc Clin Oncol 1999;18:104A.","journal-title":"Proc Am Soc Clin Oncol"},{"key":"CR31","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1093\/jnci\/82.19.1539","volume":"82","author":"G Bonadonna","year":"1990","unstructured":"Bonadonna G, Veronesi U, Brambilla C, et al. Primary chemotherapy to avoid mastectomy in tumors with diameters of three centimeters or more. J Natl Cancer Inst 1990;82:1539?1545.","journal-title":"J Natl Cancer Inst"},{"key":"CR32","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1002\/1097-0142(19940115)73:2<362::AID-CNCR2820730221>3.0.CO;2-L","volume":"73","author":"GF Schwartz","year":"1994","unstructured":"Schwartz GF, Birchansky CA, Komarnisky LT, et al. Induction chemotherapy followed by breast conservation for locally advanced carcinoma of the breast. Cancer 1994;73:362?369.","journal-title":"Cancer"},{"key":"CR33","doi-asserted-by":"crossref","first-page":"2483","DOI":"10.1200\/JCO.1997.15.7.2483","volume":"15","author":"B Fisher","year":"1997","unstructured":"Fisher B, Brown A, Mamounas E, et al. Effect of preoperative chemotherapy on local-regional disease in women with operable breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-18. J Clin Oncol 1997;15:2483?2493.","journal-title":"J Clin Oncol"},{"key":"CR34","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1016\/0140-6736(92)91591-U","volume":"339","author":"PA Cabanes","year":"1992","unstructured":"Cabanes PA, Salmon RJ, Vilcoq JR, et al. Value of axillary dissection in addition to lumpectomy and radiotherapy in early breast cancer. Lancet 1992;339:1247?1248.","journal-title":"Lancet"},{"key":"CR35","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1002\/bjs.1800670304","volume":"67","author":"AO Langlands","year":"1980","unstructured":"Langlands AO, Prescott RH, Hamilton T. A clinical trial in the management of operable cancer of the breast. Br J Surg 1980;67:170?174.","journal-title":"Br J Surg"},{"key":"CR36","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1001\/archsurg.1987.01400230030004","volume":"122","author":"J Hayward","year":"1987","unstructured":"Hayward J, Caleffi M. The significance of local control in the primary treatment of breast cancer. Arch Surg 1987;122:1244?1247.","journal-title":"Arch Surg"}],"container-title":["Annals of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10434-999-0762-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10434-999-0762-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10434-999-0762-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T16:51:08Z","timestamp":1559148668000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10434-999-0762-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,12]]},"references-count":36,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1999,12]]}},"alternative-id":["762"],"URL":"https:\/\/doi.org\/10.1007\/s10434-999-0762-4","relation":{},"ISSN":["1068-9265","1534-4681"],"issn-type":[{"value":"1068-9265","type":"print"},{"value":"1534-4681","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,12]]}}}