{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:21:06Z","timestamp":1762507266469,"version":"3.37.3"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T00:00:00Z","timestamp":1512518400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T00:00:00Z","timestamp":1512518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U01 HL119578","K24 HL8103800"],"award-info":[{"award-number":["U01 HL119578","K24 HL8103800"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000009","name":"Foundation for the National Institutes of Health","doi-asserted-by":"publisher","award":["R01 HL83359"],"award-info":[{"award-number":["R01 HL83359"]}],"id":[{"id":"10.13039\/100000009","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Biomed Eng"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1007\/s10439-017-1969-3","type":"journal-article","created":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T17:36:03Z","timestamp":1512581763000},"page":"257-269","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Interpreting Activation Mapping of Atrial Fibrillation: A Hybrid Computational\/Physiological Study"],"prefix":"10.1007","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2612-463X","authenticated-orcid":false,"given":"Francisco","family":"Sahli Costabal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junaid A. B.","family":"Zaman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6283-935X","authenticated-orcid":false,"given":"Ellen","family":"Kuhl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjiv M.","family":"Narayan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,12,6]]},"reference":[{"key":"1969_CR1","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1161\/CIRCEP.109.910125","volume":"3","author":"MA Allessie","year":"2010","unstructured":"Allessie, M. A., N. M. de Groot, R. P. Houben, U. Schotten, E. Boersma, J. L. Smeets, and H. J. Crijns. Electropathological substrate of long-standing persistent atrial fibrillation in patients with structural heart disease: longitudinal dissociation. Circ. Arrhythm. Electrophysiol. 3:606\u2013615, 2010.","journal-title":"Circ. Arrhythm. Electrophysiol."},{"key":"1969_CR2","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1161\/CIRCEP.114.002737","volume":"8","author":"E Anter","year":"2015","unstructured":"Anter, E., C. M. Tschabrunn, and M. E. Josephson. High-resolution mapping of scar-related atrial arrhythmias using smaller electrodes with closer interelectrode spacing. Circ. Arrhythm. Electrophysiol. 8:537\u2013545, 2015.","journal-title":"Circ. Arrhythm. Electrophysiol."},{"key":"1969_CR3","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1016\/j.euromechsol.2014.04.001","volume":"48","author":"B Baillargeon","year":"2014","unstructured":"Baillargeon, B., N. Rebelo, D. D. Fox, R. L. Taylor, and E. Kuhl. The Living Heart Project: a robust and integrative simulator for human heart function. Eur. J. Mech. A 48:38\u201347, 2014.","journal-title":"Eur. J. Mech. A"},{"key":"1969_CR4","volume-title":"2017 HRS\/EHRA\/ECAS\/APHRS\/SOLAECE Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation","author":"H Calkins","year":"2017","unstructured":"Calkins, H., G. Hindricks, R. Cappato, Y. H. Kim, E. B. Saad, L. Aguinaga, J. G. Akar, V. Badhwar, J. Brugada, J. Camm, P. S. Chen, S. A. Chen, M. K. Chung, J. C. Nielsen, A. B. Curtis, D. W. Davies, J. D. Day, A. d\u2019Avila, R. Natasja de Groot, L. Di Biase, M. Duytschaever, J. R. Edgerton, K. A. Ellenbogen, P. T. Ellinor, S. Ernst, G. Fenelon, E. P. Gerstenfeld, D. E. Haines, M. Haissaguerre, R. H. Helm, E. Hylek, W. M. Jackman, J. Jalife, J. M. Kalman, J. Kautzner, H. Kottkamp, K. H. Kuck, K. Kumagai, R. Lee, T. Lewalter, B. D. Lindsay, L. Macle, M. Mansour, F. E. Marchlinski, G. F. Michaud, H. Nakagawa, A. Natale, S. Nattel, K. Okumura, D. Packer, E. Pokushalov, M. R. Reynolds, P. Sanders, M. Scanavacca, R. Scanavacca, R. Schilling, C. Tondo, H. M. Tsao, A. Verma, D. J. Wilber, and T. Yamane. 2017 HRS\/EHRA\/ECAS\/APHRS\/SOLAECE Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation. Washington, DC: Heart Rhythm Society, 2017."},{"key":"1969_CR5","doi-asserted-by":"publisher","first-page":"20150083","DOI":"10.1098\/rsfs.2015.0083","volume":"6","author":"R Chabiniok","year":"2016","unstructured":"Chabiniok, R., V. Wang, M. Hadjicharalambous, L. Asner, J. Lee, M. Sermesant, E. Kuhl, A. Young, P. Moireau, M. Nash, D. Chapelle, and D. A. Nordsletten. Multiphysics and multiscale modeling, data-model fusion and integration of organ physiology in the clinic: ventricular cardiac mechanics. Interface Focus 6:20150083, 2016.","journal-title":"Interface Focus"},{"key":"1969_CR6","doi-asserted-by":"publisher","first-page":"1336","DOI":"10.1114\/B:ABME.0000042222.90548.00","volume":"32","author":"I Chouvarda","year":"2004","unstructured":"Chouvarda, I., N. Maglaveras, C. Pappas, F. J. L. Van Capelle, and J. DeBakker. Estimation of distance between a unipolar recording electrode and a myocardial bundle based on signal characteristics. Ann. Biomed. Eng. 32:1336\u20131347, 2004.","journal-title":"Ann. Biomed. Eng."},{"key":"1969_CR7","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1161\/CIRCEP.111.965145","volume":"4","author":"DD Correa de Sa","year":"2011","unstructured":"Correa de Sa, D. D., N. Thompson, J. Stinnett-Donnelly, P. Znojkiewicz, N. Habel, J. G. Muller, J. H. Bates, J. S. Buzas, and P. S. Spector. Electrogram fractionation: the relationship between spatiotemporal variation of tissue excitation and electrode spatial resolution. Circ. Arrhythm. Electrophysiol. 4:909\u2013916, 2011.","journal-title":"Circ. Arrhythm. Electrophysiol."},{"key":"1969_CR8","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1016\/S0008-6363(99)00034-6","volume":"42","author":"M Courtemanche","year":"1999","unstructured":"Courtemanche, M., R. J. Ramirez, and S. Nattel. Ionic targets for drug therapy and atrial fibrillation-induced electrical remodeling: insights from a mathematical model. Cardiovasc. Res. 42:477\u2013489, 1999.","journal-title":"Cardiovasc. Res."},{"key":"1969_CR9","doi-asserted-by":"publisher","first-page":"C163","DOI":"10.1137\/130912505","volume":"36","author":"T Dickopf","year":"2014","unstructured":"Dickopf, T., D. Krause, R. Krause, and M. Potse. Design and analysis of a lightweight parallel adaptive scheme for the solution of the monodomain equation. SIAM J. Sci. Comput. 36:C163\u2013C189, 2014.","journal-title":"SIAM J. Sci. Comput."},{"key":"1969_CR10","first-page":"237","volume":"43","author":"A Gharaviri","year":"2016","unstructured":"Gharaviri, A., M. Potse, S. Verheule, R. Krause, A. Auricchio, and U. Schotten. Epicardical fibrosis explains increased transmural conduction in a computer model of atrial fibrillation. Comput. Cardiol. 43:237\u2013240, 2016.","journal-title":"Comput. Cardiol."},{"key":"1969_CR11","doi-asserted-by":"publisher","first-page":"1830","DOI":"10.1016\/j.hrthm.2013.09.007","volume":"10","author":"B Ghoraani","year":"2013","unstructured":"Ghoraani, B., R. Dalvi, S. Gizurarson, M. Das, A. Ha, A. Suszko, S. Krishnan, and V. S. Chauhan. Localized rotational activation in the left atrium during human atrial fibrillation: relationship to complex fractionated atrial electrograms and low-voltage zones. Heart Rhythm 10:1830\u20131838, 2013.","journal-title":"Heart Rhythm"},{"key":"1969_CR12","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1002\/nme.2571","volume":"79","author":"S G\u00f6ktepe","year":"2009","unstructured":"G\u00f6ktepe, S., and E. Kuhl. Computational modeling of electrophysiology: a novel finite element approach. Int. J. Numer. Methods Eng. 79:156\u2013178, 2009.","journal-title":"Int. J. Numer. Methods Eng."},{"key":"1969_CR13","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1007\/s00466-009-0434-z","volume":"45","author":"S G\u00f6ktepe","year":"2010","unstructured":"G\u00f6ktepe, S., and E. Kuhl. Electromechanics of the heart: a unified approach to the strongly coupled excitation\u2013contraction problem. Comput. Mech. 45:227\u2013243, 2010.","journal-title":"Comput. Mech."},{"key":"1969_CR14","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1007\/s00419-009-0384-0","volume":"80","author":"S G\u00f6ktepe","year":"2010","unstructured":"G\u00f6ktepe, S., J. Wong, and E. Kuhl. Atrial and ventricular fibrillation: computational simulation of spiral waves in cardiac tissue. Arch. Appl. Mech. 80:569\u2013580, 2010.","journal-title":"Arch. Appl. Mech."},{"key":"1969_CR15","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1161\/CIRCULATIONAHA.113.005421","volume":"130","author":"M Haissaguerre","year":"2014","unstructured":"Haissaguerre, M., M. Hocini, A. Denis, A. J. Shah, Y. Komatsu, S. Yamashita, M. Daly, S. Amraoui, S. Zellerhoff, M. Q. Picat, A. Quotb, L. Jesel, H. Lim, S. Ploux, P. Bordachar, G. Attuel, V. Meillet, P. Ritter, N. Derval, F. Sacher, O. Bernus, H. Cochet, P. Jais, and R. Dubois. Driver domains in persistent atrial fibrillation. Circulation 130:530\u2013538, 2014.","journal-title":"Circulation"},{"key":"1969_CR16","doi-asserted-by":"publisher","first-page":"2390","DOI":"10.1093\/eurheartj\/ehv233","volume":"36","author":"BJ Hansen","year":"2015","unstructured":"Hansen, B. J., J. Zhao, T. A. Csepe, B. T. Moore, N. Li, L. A. Jayne, A. Kalyanasundaram, P. Lim, A. Bratasz, K. A. Powell, O. P. Simonetti, R. S. Higgins, A. Kilic, P. J. Mohler, P. M. Janssen, R. Weiss, J. D. Hummel, and V. V. Fedorov. Atrial fibrillation driven by micro-anatomic intramural re-entry revealed by simultaneous sub-epicardial and sub-endocardial optical mapping in explanted human hearts. Eur. Heart J. 36:2390\u20132401, 2015.","journal-title":"Eur. Heart J."},{"key":"1969_CR17","doi-asserted-by":"publisher","first-page":"1420","DOI":"10.1046\/j.1460-9592.2003.t01-1-00203.x","volume":"26","author":"B Herweg","year":"2003","unstructured":"Herweg, B., M. Kowalski, and J. S. Steinberg. Termination of persistent atrial fibrillation resistant to cardioversion by a single radiofrequency application. Pacing Clin. Electrophysiol. 26:1420\u20131423, 2003.","journal-title":"Pacing Clin. Electrophysiol."},{"key":"1969_CR18","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1016\/j.cma.2014.02.002","volume":"273","author":"DE Hurtado","year":"2014","unstructured":"Hurtado, D. E., and D. Henao. Gradient flows and variational principles for cardiac electrophysiology: toward efficient and robust numerical simulations of the electrical activity of the heart. Comput. Methods Appl. Mech. Eng. 273:238\u2013254, 2014.","journal-title":"Comput. Methods Appl. Mech. Eng."},{"key":"1969_CR19","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1016\/j.hrthm.2009.02.026","volume":"6","author":"V Jacquemet","year":"2009","unstructured":"Jacquemet, V., and C. S. Henriquez. Genesis of complex fractionated atrial electrograms in zones of slow conduction: a computer model of microfibrosis. Heart Rhythm 6:803\u2013810, 2009.","journal-title":"Heart Rhythm"},{"key":"1969_CR20","doi-asserted-by":"publisher","first-page":"1231","DOI":"10.1161\/01.CIR.95.5.1231","volume":"95","author":"K Konings","year":"1997","unstructured":"Konings, K., J. Smeets, O. Penn, H. Wellens, and M. Allessie. Configuration of unipolar atrial electrograms during electrically induced atrial fibrillation in humans. Circulation 95:1231\u20131241, 1997.","journal-title":"Circulation"},{"key":"1969_CR21","doi-asserted-by":"publisher","first-page":"1415","DOI":"10.1016\/j.hrthm.2015.03.017","volume":"12","author":"DH Lau","year":"2015","unstructured":"Lau, D. H., B. Maesen, S. Zeemering, P. Kuklik, A. Hunnik, T. A. Lankveld, E. Bidar, S. Verheule, J. Nijs, J. Maessen, H. Crijns, P. Sanders, and U. Schotten. Indices of bipolar complex fractionated atrial electrograms correlate poorly with each other and atrial fibrillation substrate complexity. Heart Rhythm 12:1415\u20131423, 2015.","journal-title":"Heart Rhythm"},{"key":"1969_CR22","doi-asserted-by":"publisher","first-page":"2108","DOI":"10.1161\/CIRCULATIONAHA.115.017007","volume":"132","author":"S Lee","year":"2015","unstructured":"Lee, S., J. Sahadevan, C. M. Khrestian, I. Cakulev, A. Markowitz, and A. L. Waldo. Simultaneous bi-atrial high density epicardial mapping of persistent and long-standing persistent atrial fibrillation in patients: new insights into the mechanism of its maintenance. Circulation 132:2108\u20132117, 2015.","journal-title":"Circulation"},{"key":"1969_CR23","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1007\/s10237-015-0723-8","volume":"15","author":"LC Lee","year":"2016","unstructured":"Lee, L. C., J. Sundnes, M. Geriet, J. F. Wenk, and S. T. Wall. An integrated electromechanical-growth heart model for simulating cardiac therapies. Biomech. Model. Mechanobiol. 15:791\u2013803, 2016.","journal-title":"Biomech. Model. Mechanobiol."},{"key":"1969_CR24","doi-asserted-by":"publisher","first-page":"H1398","DOI":"10.1152\/ajpheart.00411.2009","volume":"297","author":"MM Maleckar","year":"2009","unstructured":"Maleckar, M. M., J. L. Greenstein, W. R. Giles, and N. A. Trayanova. K+ current changes account for the rate dependence of the action potential in the human atrial myocyte. Am. J. Physiol. Heart Circ. Physiol. 297:H1398\u2013H1410, 2009.","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"1969_CR25","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1111\/jce.12474","volume":"25","author":"JM Miller","year":"2014","unstructured":"Miller, J. M., R. C. Kowal, V. Swarup, J. P. Daubert, E. G. Daoud, J. D. Day, K. A. Ellenbogen, J. D. Hummel, T. Baykaner, D. E. Krummen, S. M. Narayan, V. Y. Reddy, K. Shivkumar, J. S. Steinberg, and K. R. Wheelan. Initial independent outcomes from focal impulse and rotor modulation ablation for atrial fibrillation: multicenter FIRM registry. J. Cardiovasc. Electrophysiol. 25:921\u2013929, 2014.","journal-title":"J. Cardiovasc. Electrophysiol."},{"key":"1969_CR26","doi-asserted-by":"publisher","first-page":"1209","DOI":"10.1111\/j.1540-8159.2006.00525.x","volume":"29","author":"SM Narayan","year":"2006","unstructured":"Narayan, S. M., D. E. Krummen, A. M. Kahn, P. L. Karasik, and M. R. Franz. Evaluating fluctuations in human atrial fibrillatory cycle length using monophasic action potentials. Pacing Clin. Electrophysiol. 29:1209\u20131218, 2006.","journal-title":"Pacing Clin. Electrophysiol."},{"key":"1969_CR27","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1016\/j.jacc.2012.05.022","volume":"60","author":"SM Narayan","year":"2012","unstructured":"Narayan, S. M., D. E. Krummen, K. Shivkumar, P. Clopton, W.-J. Rappel, and J. Miller. Treatment of atrial fibrillation by the ablation of localized sources: the conventional ablation for atrial fibrillation with or without focal impulse and rotor modulation: CONFIRM trial. J. Am. Coll. Cardiol. 60:628\u2013636, 2012.","journal-title":"J. Am. Coll. Cardiol."},{"key":"1969_CR28","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1016\/j.hrthm.2010.10.020","volume":"8","author":"SM Narayan","year":"2011","unstructured":"Narayan, S. M., M. Wright, N. Derval, A. Jadidi, A. Forclaz, I. Nault, S. Miyazaki, F. Sacher, P. Bordachar, J. Clementy, P. Jais, M. Haissaguerre, and M. Hocini. Classifying fractionated electrograms in human atrial fibrillation using monophasic action potentials and activation mapping: evidence for localized drivers, rate acceleration and non-local signal etiologies. Heart Rhythm 8:244\u2013253, 2011.","journal-title":"Heart Rhythm"},{"key":"1969_CR29","doi-asserted-by":"publisher","first-page":"962","DOI":"10.1016\/j.hrthm.2015.12.025","volume":"13","author":"SM Narayan","year":"2016","unstructured":"Narayan, S. M., J. A. Zaman, T. Baykaner, and M. R. Franz. Atrial fibrillation: can electrograms be interpreted without repolarization information? Heart Rhythm 13:962\u2013963, 2016.","journal-title":"Heart Rhythm"},{"key":"1969_CR30","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1161\/01.RES.82.1.63","volume":"82","author":"A Nygren","year":"1998","unstructured":"Nygren, A., C. Fiset, L. Firek, J. W. Clark, D. S. Lindblad, R. B. Clark, and W. R. Giles. Mathematical model of an adult human atrial cell: the role of K+ currents in repolarization. Circ. Res. 82:63\u201381, 1998.","journal-title":"Circ. Res."},{"key":"1969_CR31","doi-asserted-by":"publisher","first-page":"3806","DOI":"10.1529\/biophysj.105.060459","volume":"88","author":"SV Pandit","year":"2005","unstructured":"Pandit, S. V., O. Berenfeld, J. M. Anumonwo, R. M. Zaritski, J. Kneller, S. Nattel, and J. Jalife. Ionic determinants of functional reentry in a 2-D model of human atrial cells during simulated chronic atrial fibrillation. Biophys. J. 88:3806\u20133821, 2005.","journal-title":"Biophys. J."},{"key":"1969_CR32","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1161\/CIRCRESAHA.111.300158","volume":"112","author":"SV Pandit","year":"2013","unstructured":"Pandit, S. V., and J. Jalife. Rotors and the dynamics of cardiac fibrillation. Circ. Res. 112:849\u2013862, 2013.","journal-title":"Circ. Res."},{"key":"1969_CR33","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1093\/cvr\/cvp164","volume":"83","author":"DM Pedrotty","year":"2009","unstructured":"Pedrotty, D. M., R. Y. Klinger, R. D. Kirkton, and N. Bursac. Cardiac fibroblast paracrine factors alter impulse conduction and ion channel expression of neonatal rat cardiomyocytes. Cardiovasc. Res. 83:688\u2013697, 2009.","journal-title":"Cardiovasc. Res."},{"key":"1969_CR34","doi-asserted-by":"publisher","first-page":"1690","DOI":"10.1007\/s10439-011-0272-y","volume":"39","author":"MK Rausch","year":"2011","unstructured":"Rausch, M. K., W. Bothe, J. P. Kvitting, J. C. Swanson, N. B. Ingels, D. C. Miller, and E. Kuhl. Characterization of mitral valve annular dynamics in the beating heart. Ann. Biomed. Eng. 39:1690\u20131702, 2011.","journal-title":"Ann. Biomed. Eng."},{"key":"1969_CR35","doi-asserted-by":"publisher","first-page":"2171","DOI":"10.1007\/s10439-013-0813-7","volume":"41","author":"MK Rausch","year":"2013","unstructured":"Rausch, M. K., F. A. Tibayan, N. B. Ingels, D. C. Miller, and E. Kuhl. Mechanics of the mitral annulus in chronic ischemic cardiomyopathy. Ann. Biomed. Eng. 41:2171\u20132180, 2013.","journal-title":"Ann. Biomed. Eng."},{"key":"1969_CR36","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1007\/s10439-016-1766-4","volume":"45","author":"CH Roney","year":"2017","unstructured":"Roney, C. H., C. D. Cantwell, N. A. Qureshi, R. A. Chowdhury, E. Dupont, P. B. Lim, E. J. Vigmond, J. H. Tweedy, F. S. Ng, and N. S. Peters. Rotor tracking using phase of electrograms recorded during atrial fibrillation. Ann. Biomed. Eng. 45:910\u2013923, 2017.","journal-title":"Ann. Biomed. Eng."},{"key":"1969_CR37","doi-asserted-by":"publisher","first-page":"3293","DOI":"10.1161\/01.CIR.0000147781.02738.13","volume":"110","author":"J Sahadevan","year":"2004","unstructured":"Sahadevan, J., K. Ryu, L. Peltz, C. M. Khrestian, R. W. Stewart, A. H. Markowitz, and A. L. Waldo. Epicardial mapping of chronic atrial fibrillation in patients: preliminary observations. Circulation 110:3293\u20133299, 2004.","journal-title":"Circulation"},{"key":"1969_CR38","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1016\/j.cma.2017.03.015","volume":"320","author":"F Sahli Costabal","year":"2017","unstructured":"Sahli Costabal, F., F. A. Concha, D. E. Hurtado, and E. Kuhl. The importance of mechano-electrical feedback and inertia in cardiac electromechanics. Comput. Methods Appl. Mech. Eng. 320:352\u2013368, 2017.","journal-title":"Comput. Methods Appl. Mech. Eng."},{"key":"1969_CR39","doi-asserted-by":"publisher","first-page":"2455","DOI":"10.1016\/j.jbiomech.2015.12.025","volume":"49","author":"F Sahli Costabal","year":"2016","unstructured":"Sahli Costabal, F., D. E. Hurtado, and E. Kuhl. Generating Purkinje networks in the human heart. J. Biomech. 49:2455\u20132465, 2016.","journal-title":"J. Biomech."},{"key":"1969_CR40","doi-asserted-by":"publisher","first-page":"H1146","DOI":"10.1152\/ajpheart.00668.2011","volume":"302","author":"C Sanchez","year":"2012","unstructured":"Sanchez, C., A. Corrias, A. Bueno-Orovio, M. Davies, J. Swinton, I. Jacobson, P. Laguna, E. Pueyo, and B. Rodriguez. The Na+\/K+ pump is an important modulator of refractoriness and rotor dynamics in human atrial tissue. AJP Heart Circ. Physiol. 302:H1146\u2013H1159, 2012.","journal-title":"AJP Heart Circ. Physiol."},{"key":"1969_CR41","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1111\/jce.12874","volume":"27","author":"P Sommer","year":"2016","unstructured":"Sommer, P., S. Kircher, S. Rolf, S. John, A. Arya, B. Dinov, S. Richter, A. Bollmann, and G. Hindricks. Successful repeat catheter ablation of recurrent longstanding persistent atrial fibrillation with rotor elimination as the procedural endpoint: a case series. J. Cardiovasc. Electrophysiol. 27:274\u2013280, 2016.","journal-title":"J. Cardiovasc. Electrophysiol."},{"key":"1969_CR42","doi-asserted-by":"publisher","first-page":"3592","DOI":"10.1007\/s10439-010-0100-9","volume":"38","author":"RJ Spiteri","year":"2010","unstructured":"Spiteri, R. J., and R. C. Dean. Stiffness analysis of cardiac electrophysiological models. Ann. Biomed. Eng. 38:3592\u20133604, 2010.","journal-title":"Ann. Biomed. Eng."},{"key":"1969_CR43","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1007\/s10877-013-9508-8","volume":"28","author":"NC Thompson","year":"2014","unstructured":"Thompson, N. C., J. Stinnett-Donnelly, N. Habel, B. Benson, J. H. Bates, B. E. Sobel, and P. S. Spector. Improved spatial resolution and electrogram wave direction independence with the use of an orthogonal electrode configuration. J. Clin. Monit. Comput. 28:157\u2013163, 2014.","journal-title":"J. Clin. Monit. Comput."},{"key":"1969_CR44","first-page":"2145","volume":"6","author":"G Tomassoni","year":"2015","unstructured":"Tomassoni, G., S. Duggal, M. Muir, L. Hutchins, K. Turner, A. M. McLoney, and A. Hesselson. Long-term follow-up of FIRM-guided ablation of atrial fibrillation: a single-center experience. J. Innov. Card. Rhythm Manag. 6:2145\u20132151, 2015.","journal-title":"J. Innov. Card. Rhythm Manag."},{"key":"1969_CR45","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1161\/01.RES.85.5.428","volume":"85","author":"DR Van Wagoner","year":"1999","unstructured":"Van Wagoner, D. R., A. L. Pond, M. Lamorgese, S. S. Rossie, P. M. McCarthy, and J. M. Nerbonne. Atrial L-type Ca2+ currents and human atrial fibrillation. Circ. Res. 85:428\u2013436, 1999.","journal-title":"Circ. Res."},{"key":"1969_CR46","doi-asserted-by":"publisher","first-page":"772","DOI":"10.1161\/01.RES.80.6.772","volume":"80","author":"DR Van Wagoner","year":"1997","unstructured":"Van Wagoner, D. R., A. L. Pond, P. M. McCarthy, J. S. Trimmer, and J. M. Nerbonne. Outward potassium current densities and Kv1.5 expression are reduced in chronic human atrial fibrillation. Circ. Res. 80:772\u2013781, 1997.","journal-title":"Circ. Res."},{"key":"1969_CR47","doi-asserted-by":"publisher","first-page":"1812","DOI":"10.1056\/NEJMoa1408288","volume":"372","author":"A Verma","year":"2015","unstructured":"Verma, A., C. Y. Jiang, T. R. Betts, J. Chen, I. Deisenhofer, R. Mantovan, L. Macle, C. A. Morillo, W. Haverkamp, R. Weerasooriya, J. P. Albenque, S. Nardi, E. Menardi, P. Novak, and P. Sanders. Approaches to catheter ablation for persistent atrial fibrillation. N. Engl. J. Med. 372:1812\u20131822, 2015.","journal-title":"N. Engl. J. Med."},{"key":"1969_CR48","doi-asserted-by":"publisher","first-page":"1536","DOI":"10.1016\/j.hrthm.2016.03.019","volume":"13","author":"E Vigmond","year":"2016","unstructured":"Vigmond, E., A. Pashaei, S. Amraoui, H. Cochet, and M. Hassaguerre. Percolation as a mechanism to explain atrial fractionated electrograms and reentry in a fibrosis model based on imaging data. Heart Rhythm 13:1536\u20131543, 2016.","journal-title":"Heart Rhythm"},{"key":"1969_CR49","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1002\/cnm.2593","volume":"30","author":"G Vigueras","year":"2014","unstructured":"Vigueras, G., I. Roy, A. Cookson, J. Lee, N. Smith, and D. Nordsletten. Toward GPGPU accelerated human electromechanical cardiac simulations. Int. J. Numer. Methods Biomed. Eng. 30:117\u2013134, 2014.","journal-title":"Int. J. Numer. Methods Biomed. Eng."},{"key":"1969_CR50","first-page":"18","volume":"1","author":"TE Walters","year":"2015","unstructured":"Walters, T. E., G. Lee, G. Morris, S. Spence, M. Larobina, V. Atkinson, P. Antippa, J. Goldblatt, A. Royse, M. O\u2019Keefe, P. Sanders, J. B. Morton, P. M. Kistler, and J. M. K. Kalman. Temporal stability of rotors and atrial activation patterns in persistent human atrial fibrillation: a high density epicardial mapping study of prolonged recordings. J. Am. Coll. Cardiol. Clin. Electrophysiol. 1:18\u201325, 2015.","journal-title":"J. Am. Coll. Cardiol. Clin. Electrophysiol."},{"key":"1969_CR51","first-page":"487","volume":"3","author":"M Wilhelms","year":"2012","unstructured":"Wilhelms, M., H. Hettmann, M. M. Maleckar, J. T. Koivumaki, O. Dossel, and G. Seemann. Benchmarking electrophysiological models of human atrial myocytes. Front. Physiol. 3:487, 2012.","journal-title":"Front. Physiol."},{"key":"1969_CR52","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1093\/cvr\/cvw073","volume":"110","author":"S Zahid","year":"2016","unstructured":"Zahid, S., H. Cochet, P. M. Boyle, E. L. Schwarz, K. N. Whyte, E. J. Vigmond, R. Dubois, M. Hocini, M. Haissaguerre, P. Jais, and N. A. Trayanova. Patient-derived models link re-entrant driver localization in atrial fibrillation to fibrosis spatial pattern. Cardiovasc. Res. 110:443\u2013454, 2016.","journal-title":"Cardiovasc. Res."}],"container-title":["Annals of Biomedical Engineering"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10439-017-1969-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10439-017-1969-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10439-017-1969-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,16]],"date-time":"2020-05-16T20:36:36Z","timestamp":1589661396000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10439-017-1969-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,6]]},"references-count":52,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["1969"],"URL":"https:\/\/doi.org\/10.1007\/s10439-017-1969-3","relation":{},"ISSN":["0090-6964","1573-9686"],"issn-type":[{"type":"print","value":"0090-6964"},{"type":"electronic","value":"1573-9686"}],"subject":[],"published":{"date-parts":[[2017,12,6]]},"assertion":[{"value":"13 September 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 November 2017","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 December 2017","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}