{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T22:38:15Z","timestamp":1784673495841,"version":"3.55.0"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2021,3,22]],"date-time":"2021-03-22T00:00:00Z","timestamp":1616371200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,3,22]],"date-time":"2021-03-22T00:00:00Z","timestamp":1616371200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Biomed Eng"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1007\/s10439-021-02764-5","type":"journal-article","created":{"date-parts":[[2021,3,22]],"date-time":"2021-03-22T21:18:12Z","timestamp":1616447892000},"page":"2734-2746","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Preseason Cerebrovascular Function in Adolescent Athletes"],"prefix":"10.1007","volume":"49","author":[{"given":"Patricia R.","family":"Roby","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Duquette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zachary Y.","family":"Kerr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johna K.","family":"Register-Mihalik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee","family":"Stoner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6085-8322","authenticated-orcid":false,"given":"Jason P.","family":"Mihalik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,3,22]]},"reference":[{"key":"2764_CR1","unstructured":"Aaslid R. Visually Evoked Dynamic Blood Flow Response of the Human Cerebral Circulation. http:\/\/stroke.ahajournals.org\/. Accessed September 20, 2018."},{"issue":"1","key":"2764_CR2","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1056\/NEJM199807023390102","volume":"339","author":"RJ Adams","year":"1998","unstructured":"Adams, R. J., V. C. McKie, L. Hsu, et al. Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonography. N. Engl. J. Med. 339(1):5\u201311, 1998.","journal-title":"N. Engl. J. Med."},{"issue":"9","key":"2764_CR3","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1056\/NEJM199202273260905","volume":"326","author":"R Adams","year":"1992","unstructured":"Adams, R., V. McKie, F. Nichols, et al. The use of ultrasonography to predict stroke in sickle cell disease. N. Engl. J. Med. 326(9):605\u2013610, 1992.","journal-title":"N. Engl. J. Med."},{"issue":"9","key":"2764_CR4","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2017.197","volume":"7","author":"ML Alosco","year":"2017","unstructured":"Alosco, M. L., A. B. Kasimis, J. M. Stamm, et al. Age of first exposure to American football and long-term neuropsychiatric and cognitive outcomes. Transl Psychiatry. 7(9):2017. https:\/\/doi.org\/10.1038\/tp.2017.197.","journal-title":"Transl Psychiatry."},{"issue":"10","key":"2764_CR5","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1007\/s002590050148","volume":"24","author":"H Barthel","year":"1997","unstructured":"Barthel, H., M. Wiener, C. Dannenberg, S. Bettin, B. Sattler, and W. H. Knapp. Age-specific cerebral perfusion in 4- to 15-year-old children: a high-resolution brain SPET study using 99mTc-ECD. Eur. J. Nucl. Med. 24(10):1245\u20131252, 1997. https:\/\/doi.org\/10.1007\/s002590050148.","journal-title":"Eur. J. Nucl. Med."},{"issue":"2","key":"2764_CR6","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1007\/s11682-012-9164-5","volume":"6","author":"CM Baugh","year":"2012","unstructured":"Baugh, C. M., J. M. Stamm, D. O. Riley, et al. Chronic traumatic encephalopathy: neurodegeneration following repetitive concussive and subconcussive brain trauma. Brain Imaging Behav. 6(2):244\u2013254, 2012. https:\/\/doi.org\/10.1007\/s11682-012-9164-5.","journal-title":"Brain Imaging Behav."},{"issue":"3\u20134","key":"2764_CR7","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1111\/j.1469-7610.2006.01611.x","volume":"47","author":"S-J Blakemore","year":"2006","unstructured":"Blakemore, S.-J., and S. Choudhury. Development of the adolescent brain: implications for executive function and social cognition. J. Child Psychol. Psychiatry 47(3\u20134):296\u2013312, 2006. https:\/\/doi.org\/10.1111\/j.1469-7610.2006.01611.x.","journal-title":"J. Child Psychol. Psychiatry"},{"issue":"4","key":"2764_CR8","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1177\/1941738119849076","volume":"11","author":"BL Brett","year":"2019","unstructured":"Brett, B. L., D. L. Huber, A. Wild, L. D. Nelson, and M. A. McCrea. Age of first exposure to american football and behavioral, cognitive, psychological, and physical outcomes in high school and collegiate football players. Sports Health. 11(4):332\u2013342, 2019. https:\/\/doi.org\/10.1177\/1941738119849076.","journal-title":"Sports Health."},{"issue":"21","key":"2764_CR9","doi-asserted-by":"publisher","first-page":"e2935","DOI":"10.1212\/WNL.0000000000010672","volume":"95","author":"JB Caccese","year":"2020","unstructured":"Caccese, J. B., Z. Houck, T. W. Kaminski, et al. Estimated age of first exposure to American football and outcome from concussion. Neurology. 95(21):e2935\u2013e2944, 2020. https:\/\/doi.org\/10.1212\/WNL.0000000000010672.","journal-title":"Neurology."},{"issue":"11","key":"2764_CR10","doi-asserted-by":"publisher","first-page":"1479","DOI":"10.1080\/02699052.2019.1644375","volume":"33","author":"AA Champagne","year":"2019","unstructured":"Champagne, A. A., N. S. Coverdale, M. Germuska, and D. J. Cook. Multi-parametric analysis reveals metabolic and vascular effects driving differences in BOLD-based cerebrovascular reactivity associated with a history of sport concussion. Brain Inj. 33(11):1479\u20131489, 2019. https:\/\/doi.org\/10.1080\/02699052.2019.1644375.","journal-title":"Brain Inj."},{"issue":"9","key":"2764_CR11","doi-asserted-by":"publisher","first-page":"2276","DOI":"10.1177\/0363546516648141","volume":"44","author":"EY Chin","year":"2016","unstructured":"Chin, E. Y., L. D. Nelson, W. B. Barr, P. McCrory, and M. A. McCrea. Reliability and validity of the sport concussion assessment tool-3 (SCAT3) in high school and collegiate athletes. Am. J. Sports Med. 44(9):2276\u20132285, 2016. https:\/\/doi.org\/10.1177\/0363546516648141.","journal-title":"Am. J. Sports Med."},{"issue":"5","key":"2764_CR12","first-page":"696","volume":"33","author":"C Chiron","year":"1992","unstructured":"Chiron, C., C. Raynaud, B. Maziere, et al. Changes in regional cerebral blood flow during brain maturation in children and adolescents. J. Nucl. Med. 33(5):696\u2013703, 1992.","journal-title":"J. Nucl. Med."},{"key":"2764_CR13","doi-asserted-by":"publisher","first-page":"870","DOI":"10.1152\/japplphysiol.00906.2006","volume":"102","author":"JA Claasen","year":"2007","unstructured":"Claasen, J. A., R. Zhang, Q. Fu, S. Witkowski, and B. Levine. Transcranial Doppler estimation of cerebral blood flow and cerebrovascular conductance during modified rebreathing. J Appl Physiol. 102:870\u2013877, 2007. https:\/\/doi.org\/10.1152\/japplphysiol.00906.2006.","journal-title":"J Appl Physiol."},{"issue":"10","key":"2764_CR14","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1038\/13158","volume":"2","author":"JN Giedd","year":"1999","unstructured":"Giedd, J. N., J. Blumenthal, N. O. Jeffries, et al. Brain development during childhood and adolescence: a longitudinal MRI study. Nat. Neurosci. 2(10):861\u2013863, 1999. https:\/\/doi.org\/10.1038\/13158.","journal-title":"Nat. Neurosci."},{"issue":"25","key":"2764_CR15","doi-asserted-by":"publisher","first-page":"425","DOI":"10.3238\/arztebl.2013.0425","volume":"110","author":"K Konrad","year":"2013","unstructured":"Konrad, K., C. Firk, and P. J. Uhlhaas. Brain development during adolescence: neuroscientific insights into this developmental period. Dtsch Arztebl Int. 110(25):425\u2013431, 2013. https:\/\/doi.org\/10.3238\/arztebl.2013.0425.","journal-title":"Dtsch Arztebl Int."},{"issue":"12","key":"2764_CR16","doi-asserted-by":"publisher","first-page":"2241","DOI":"10.1249\/MSS.0b013e3182249539","volume":"43","author":"TK Len","year":"2011","unstructured":"Len, T. K., J. P. Neary, G. J. G. Asmundson, D. G. Goodman, B. Bjornson, and Y. N. Bhambhani. Cerebrovascular reactivity impairment after sport-induced concussion. Med. Sci. Sports Exerc. 43(12):2241\u20132248, 2011. https:\/\/doi.org\/10.1249\/MSS.0b013e3182249539.","journal-title":"Med. Sci. Sports Exerc."},{"issue":"3","key":"2764_CR17","doi-asserted-by":"publisher","first-page":"346","DOI":"10.3109\/02699052.2012.743185","volume":"27","author":"TK Len","year":"2013","unstructured":"Len, T. K., J. P. Neary, G. J. G. Asmundson, et al. Serial monitoring of CO2 reactivity following sport concussion using hypocapnia and hypercapnia. Brain Inj. 27(3):346\u2013353, 2013. https:\/\/doi.org\/10.3109\/02699052.2012.743185.","journal-title":"Brain Inj."},{"issue":"1","key":"2764_CR18","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1097\/01.CSMR.0000308671.45558.e2","volume":"7","author":"MR Lovell","year":"2008","unstructured":"Lovell, M. R., and V. Fazio. Concussion management in the child and adolescent athlete. Curr Sports Med Rep. 7(1):12\u201315, 2008. https:\/\/doi.org\/10.1097\/01.CSMR.0000308671.45558.e2.","journal-title":"Curr Sports Med Rep."},{"issue":"10","key":"2764_CR19","doi-asserted-by":"publisher","first-page":"2703","DOI":"10.1016\/j.jstrokecerebrovasdis.2018.05.042","volume":"27","author":"RDS Macedo-Campos","year":"2018","unstructured":"Macedo-Campos, R. D. S., S. A. Adegoke, M. S. Figueiredo, J. A. P. Braga, and G. S. Silva. Cerebral vasoreactivity in children with sickle cell disease: a transcranial Doppler study. J Stroke Cerebrovasc Dis. 27(10):2703\u20132706, 2018. https:\/\/doi.org\/10.1016\/j.jstrokecerebrovasdis.2018.05.042.","journal-title":"J Stroke Cerebrovasc Dis."},{"key":"2764_CR20","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1161\/01.STR.23.5.668","volume":"23","author":"HS Markus","year":"1992","unstructured":"Markus, H. S., and M. J. Harrison. Estimation of cerebrovascular reactivity using transcranial Doppler, including the use of breath-holding as the vasodilatory stimulus. Stroke 23:668\u2013673, 1992.","journal-title":"Stroke"},{"issue":"2","key":"2764_CR21","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1089\/neu.2016.4413","volume":"34","author":"PH Montenigro","year":"2017","unstructured":"Montenigro, P. H., M. L. Alosco, B. M. Martin, et al. Cumulative head impact exposure predicts later-life depression, apathy, executive dysfunction, and cognitive impairment in former high school and college football players. J. Neurotrauma 34(2):328\u2013340, 2017. https:\/\/doi.org\/10.1089\/neu.2016.4413.","journal-title":"J. Neurotrauma"},{"issue":"7","key":"2764_CR22","doi-asserted-by":"publisher","first-page":"3188","DOI":"10.1002\/hbm.22394","volume":"35","author":"P Moses","year":"2014","unstructured":"Moses, P., M. DiNino, L. Hernandez, and T. T. Liu. Developmental changes in resting and functional cerebral blood flow and their relationship to the BOLD response. Hum. Brain Mapp. 35(7):3188\u20133198, 2014. https:\/\/doi.org\/10.1002\/hbm.22394.","journal-title":"Hum. Brain Mapp."},{"key":"2764_CR23","unstructured":"NCAA. Estimated probability of competing in college athletics. http:\/\/www.ncaa.org\/about\/resources\/research\/estimated-probability-competing-professional-athletics. Published April 3, 2019. Accessed February 10, 2020."},{"issue":"3","key":"2764_CR24","doi-asserted-by":"publisher","first-page":"175","DOI":"10.4085\/1062-6050-52.1.15","volume":"52","author":"KL O\u2019Connor","year":"2017","unstructured":"O\u2019Connor, K. L., M. M. Baker, S. L. Dalton, T. P. Dompier, S. P. Broglio, and Z. Y. Kerr. Epidemiology of sport-related concussions in high school athletes: national athletic treatment, injury and outcomes network (NATION), 2011-2012 through 2013-2014. J. Athl. Train. 52(3):175\u2013185, 2017. https:\/\/doi.org\/10.4085\/1062-6050-52.1.15.","journal-title":"J. Athl. Train."},{"issue":"4","key":"2764_CR25","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1177\/0271678X15617954","volume":"36","author":"AA Phillips","year":"2016","unstructured":"Phillips, A. A., F. H. Chan, M. M. Z. Zheng, A. V. Krassioukov, and P. N. Ainslie. Neurovascular coupling in humans: physiology, methodological advances and clinical implications. J. Cereb. Blood Flow Metab. 36(4):647\u2013664, 2016. https:\/\/doi.org\/10.1177\/0271678X15617954.","journal-title":"J. Cereb. Blood Flow Metab."},{"issue":"16","key":"2764_CR26","doi-asserted-by":"publisher","first-page":"2385","DOI":"10.1089\/neu.2018.5861","volume":"36","author":"S Purkayastha","year":"2019","unstructured":"Purkayastha, S., F. A. Sorond, S. Lyng, et al. Impaired cerebral vasoreactivity despite symptom resolution in sports-related concussion. J. Neurotrauma 36(16):2385\u20132390, 2019. https:\/\/doi.org\/10.1089\/neu.2018.5861.","journal-title":"J. Neurotrauma"},{"issue":"8","key":"2764_CR27","doi-asserted-by":"publisher","first-page":"1457","DOI":"10.1080\/17470210902816461","volume":"62","author":"K Rayner","year":"2009","unstructured":"Rayner, K. Eye movements and attention in reading, scene perception, and visual search. Q. J. Exp. Psychol. 62(8):1457\u20131506, 2009. https:\/\/doi.org\/10.1080\/17470210902816461.","journal-title":"Q. J. Exp. Psychol."},{"issue":"2","key":"2764_CR28","doi-asserted-by":"publisher","first-page":"245","DOI":"10.3758\/BF03212426","volume":"3","author":"K Rayner","year":"1996","unstructured":"Rayner, K., and G. E. Raney. Eye movement control in reading and visual search: effects of word frequency. Psychon. Bull. Rev. 3(2):245\u2013248, 1996. https:\/\/doi.org\/10.3758\/BF03212426.","journal-title":"Psychon. Bull. Rev."},{"key":"2764_CR29","doi-asserted-by":"publisher","DOI":"10.1007\/s10439-020-02514-z","author":"PR Roby","year":"2020","unstructured":"Roby, P. R., A. Chandran, N. E. Barczak-Scarboro, et al. Cerebrovascular reactivity in special operations forces combat soldiers. Ann. Biomed. Eng. April 2020. https:\/\/doi.org\/10.1007\/s10439-020-02514-z.","journal-title":"Ann. Biomed. Eng."},{"key":"2764_CR30","doi-asserted-by":"publisher","DOI":"10.1007\/s10439-020-02604-y","author":"PR Roby","year":"2020","unstructured":"Roby, P. R., J. P. DeCicco, A. Chandran, et al. Neurovascular coupling in special operations forces combat soldiers. Ann. Biomed. Eng. 2020. https:\/\/doi.org\/10.1007\/s10439-020-02604-y.","journal-title":"Ann. Biomed. Eng."},{"issue":"23","key":"2764_CR31","doi-asserted-by":"publisher","first-page":"8643","DOI":"10.1073\/pnas.1400178111","volume":"111","author":"TD Satterthwaite","year":"2014","unstructured":"Satterthwaite, T. D., R. T. Shinohara, D. H. Wolf, et al. Impact of puberty on the evolution of cerebral perfusion during adolescence. Proc. Natl. Acad. Sci. U.S.A. 111(23):8643\u20138648, 2014. https:\/\/doi.org\/10.1073\/pnas.1400178111.","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"16","key":"2764_CR32","doi-asserted-by":"publisher","first-page":"2122","DOI":"10.1001\/jama.283.16.2122","volume":"283","author":"M Silvestrini","year":"2000","unstructured":"Silvestrini, M., F. Vernieri, P. Pasqualetti, et al. Impaired cerebral vasoreactivity and risk of stroke in patients with asymptomatic carotid artery stenosis. JAMA 283(16):2122\u20132127, 2000. https:\/\/doi.org\/10.1001\/jama.283.16.2122.","journal-title":"JAMA"},{"key":"2764_CR33","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/j.jneumeth.2016.06.007","volume":"270","author":"JD Smirl","year":"2016","unstructured":"Smirl, J. D., A. D. Wright, K. Bryk, and P. V. Donkelaar. Where\u2019s Waldo? The utility of a complicated visual search paradigm for transcranial Doppler-based assessments of neurovascular coupling. J. Neurosci. Methods 270:92\u2013101, 2016.","journal-title":"J. Neurosci. Methods"},{"issue":"11","key":"2764_CR34","doi-asserted-by":"publisher","first-page":"1114","DOI":"10.1212\/WNL.0000000000001358","volume":"84","author":"JM Stamm","year":"2015","unstructured":"Stamm, J. M., A. P. Bourlas, C. M. Baugh, et al. Age of first exposure to football and later-life cognitive impairment in former NFL players. Neurology. 84(11):1114\u20131120, 2015. https:\/\/doi.org\/10.1212\/WNL.0000000000001358.","journal-title":"Neurology."},{"issue":"22","key":"2764_CR35","doi-asserted-by":"publisher","first-page":"1768","DOI":"10.1089\/neu.2014.3822","volume":"32","author":"JM Stamm","year":"2015","unstructured":"Stamm, J. M., I. K. Koerte, M. Muehlmann, et al. Age at first exposure to football is associated with altered corpus callosum white matter microstructure in former professional football players. J. Neurotrauma 32(22):1768\u20131776, 2015. https:\/\/doi.org\/10.1089\/neu.2014.3822.","journal-title":"J. Neurotrauma"},{"issue":"4","key":"2764_CR36","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1002\/jum.14782","volume":"38","author":"J Staszewski","year":"2019","unstructured":"Staszewski, J., E. Skrobowska, R. Piusi\u0144ska-Macoch, B. Brodacki, and A. St\u0119pie\u0144. Cerebral and extracerebral vasoreactivity in patients with different clinical manifestations of cerebral small-vessel disease: data from the significance of hemodynamic and hemostatic factors in the course of different manifestations of cerebral small-vessel disease study. J. Ultrasound Med. 38(4):975\u2013987, 2019. https:\/\/doi.org\/10.1002\/jum.14782.","journal-title":"J. Ultrasound Med."},{"issue":"2","key":"2764_CR37","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1080\/87565641.2014.973959","volume":"40","author":"DO Svaldi","year":"2015","unstructured":"Svaldi, D. O., C. Joshi, M. E. Robinson, et al. Cerebrovascular reactivity alterations in asymptomatic high school football players. Dev Neuropsychol. 40(2):80\u201384, 2015. https:\/\/doi.org\/10.1080\/87565641.2014.973959.","journal-title":"Dev Neuropsychol."},{"issue":"1","key":"2764_CR38","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1007\/s11682-016-9509-6","volume":"11","author":"DO Svaldi","year":"2017","unstructured":"Svaldi, D. O., E. C. McCuen, C. Joshi, et al. Cerebrovascular reactivity changes in asymptomatic female athletes attributable to high school soccer participation. Brain Imaging Behav. 11(1):98\u2013112, 2017. https:\/\/doi.org\/10.1007\/s11682-016-9509-6.","journal-title":"Brain Imaging Behav."},{"key":"2764_CR39","doi-asserted-by":"publisher","first-page":"590","DOI":"10.3389\/fneur.2019.00590","volume":"10","author":"CM Thibeault","year":"2019","unstructured":"Thibeault, C. M., S. Thorpe, N. Canac, S. J. Wilk, and R. B. Hamilton. Sex-based differences in transcranial Doppler ultrasound and self-reported symptoms after mild traumatic brain injury. Front Neurol. 10:590, 2019. https:\/\/doi.org\/10.3389\/fneur.2019.00590.","journal-title":"Front Neurol."},{"key":"2764_CR40","doi-asserted-by":"publisher","first-page":"200","DOI":"10.3389\/fneur.2018.00200","volume":"9","author":"CM Thibeault","year":"2018","unstructured":"Thibeault, C. M., S. Thorpe, M. J. O\u2019Brien, et al. A cross-sectional study on cerebral hemodynamics after mild traumatic brain injury in a pediatric population. Front Neurol. 9:200, 2018. https:\/\/doi.org\/10.3389\/fneur.2018.00200.","journal-title":"Front Neurol."},{"key":"2764_CR41","doi-asserted-by":"crossref","unstructured":"Totaro, R., C. Marini, M. Baldassarre, and A. Carolei. Cerebrovascular reactivity evaluated by transcranial Doppler: reproducibility of different methods, 1999, pp. 142\u2013145. https:\/\/www.karger.com\/Article\/Pdf\/15943. Accessed January 13, 2019.","DOI":"10.1159\/000015943"},{"issue":"4","key":"2764_CR42","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1212\/01.wnl.0000230150.39429.8e","volume":"67","author":"N Valadi","year":"2006","unstructured":"Valadi, N., G. S. Silva, L. S. Bowman, et al. Transcranial Doppler ultrasonography in adults with sickle cell disease. Neurology. 67(4):572\u2013574, 2006. https:\/\/doi.org\/10.1212\/01.wnl.0000230150.39429.8e.","journal-title":"Neurology."},{"issue":"2","key":"2764_CR43","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/j.jneumeth.2011.01.011","volume":"196","author":"CK Willie","year":"2011","unstructured":"Willie, C. K., F. L. Colino, D. M. Bailey, et al. Utility of transcranial Doppler ultrasound for the integrative assessment of cerebrovascular function. J. Neurosci. Methods 196(2):221\u2013237, 2011. https:\/\/doi.org\/10.1016\/j.jneumeth.2011.01.011.","journal-title":"J. Neurosci. Methods"},{"key":"2764_CR44","doi-asserted-by":"publisher","DOI":"10.1097\/JSM.0000000000000578","author":"AD Wright","year":"2018","unstructured":"Wright, A. D., J. D. Smirl, K. Bryk, M. Jakovac, and P. van Donkelaar. A prospective transcranial doppler ultrasound-based evaluation of the effects of repetitive subconcussive head trauma on neurovascular coupling dynamics. Clin. J. Sport Med. 2018. https:\/\/doi.org\/10.1097\/JSM.0000000000000578.","journal-title":"Clin. J. Sport Med."},{"issue":"22","key":"2764_CR45","doi-asserted-by":"publisher","first-page":"3097","DOI":"10.1089\/neu.2017.5020","volume":"34","author":"AD Wright","year":"2017","unstructured":"Wright, A. D., J. D. Smirl, K. Bryk, and P. van Donkelaar. A prospective transcranial Doppler ultrasound-based evaluation of the acute and cumulative effects of sport-related concussion on neurovascular coupling response dynamics. J. Neurotrauma 34(22):3097\u20133106, 2017. https:\/\/doi.org\/10.1089\/neu.2017.5020.","journal-title":"J. Neurotrauma"}],"container-title":["Annals of Biomedical Engineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10439-021-02764-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10439-021-02764-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10439-021-02764-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,13]],"date-time":"2021-10-13T06:46:45Z","timestamp":1634107605000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10439-021-02764-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,22]]},"references-count":45,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["2764"],"URL":"https:\/\/doi.org\/10.1007\/s10439-021-02764-5","relation":{},"ISSN":["0090-6964","1573-9686"],"issn-type":[{"value":"0090-6964","type":"print"},{"value":"1573-9686","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,22]]},"assertion":[{"value":"20 October 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 February 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 March 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}