{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T19:29:02Z","timestamp":1783970942742,"version":"3.55.0"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,9,20]],"date-time":"2022-09-20T00:00:00Z","timestamp":1663632000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,9,20]],"date-time":"2022-09-20T00:00:00Z","timestamp":1663632000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Biomed Eng"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1007\/s10439-022-03079-9","type":"journal-article","created":{"date-parts":[[2022,9,20]],"date-time":"2022-09-20T14:06:49Z","timestamp":1663682809000},"page":"211-224","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["In Silico Evaluation of the Medtronic 780G System While Using the GS3 and Its Calibration-Free Successor, the G4S Sensor"],"prefix":"10.1007","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7109-6615","authenticated-orcid":false,"given":"Benyamin","family":"Grosman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neha","family":"Parikh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anirban","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis","family":"Lintereur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Vigersky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ohad","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Rhinehart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,9,20]]},"reference":[{"key":"3079_CR1","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1056\/NEJMoa1303576","volume":"369","author":"RM Bergenstal","year":"2013","unstructured":"Bergenstal, R. M., D. C. Klonoff, S. K. Garg, et al. Threshold-based insulin-pump interruption for reduction of hypoglycemia. N. Engl. J. Med. 369:224\u2013232, 2013.","journal-title":"N. Engl. J. Med."},{"key":"3079_CR2","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1016\/S0140-6736(20)32514-9","volume":"397","author":"RM Bergenstal","year":"2021","unstructured":"Bergenstal, R. M., R. Nimri, R. W. Beck, et al. A comparison of two hybrid closed-loop systems in adolescents and young adults with type 1 diabetes (FLAIR): a multicentre, randomised, crossover trial. Lancet. 397:208\u2013219, 2021.","journal-title":"Lancet"},{"key":"3079_CR3","doi-asserted-by":"publisher","first-page":"1456","DOI":"10.1172\/JCI110398","volume":"68","author":"RN Bergman","year":"1981","unstructured":"Bergman, R. N., L. S. Phillips, and C. Cobelli. Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose. J. Clin. Investig. 68:1456\u20131467, 1981.","journal-title":"J. Clin. Investig."},{"key":"3079_CR4","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1089\/dia.2021.0319","volume":"24","author":"AL Carlson","year":"2022","unstructured":"Carlson, A. L., J. L. Sherr, D. I. Shulman, et al. Safety and glycemic outcomes during the MiniMed advanced hybrid closed-loop system pivotal trial in adolescents and adults with type 1 diabetes. Diabetes Technol. Ther. 24:178\u2013189, 2022.","journal-title":"Diabetes Technol. Ther."},{"key":"3079_CR5","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1109\/RBME.2009.2036073","volume":"2","author":"C Cobelli","year":"2009","unstructured":"Cobelli, C., C. D. Man, G. Sparacino, L. Magni, G. De Nicolao, and B. P. Kovatchev. Diabetes: models, signals, and control. IEEE Rev. Biomed. Eng. 2:54\u201396, 2009.","journal-title":"IEEE Rev. Biomed. Eng."},{"key":"3079_CR6","doi-asserted-by":"publisher","first-page":"969","DOI":"10.2337\/dc20-2250","volume":"44","author":"OJ Collyns","year":"2021","unstructured":"Collyns, O. J., R. A. Meier, Z. L. Betts, et al. Improved glycemic outcomes with Medtronic MiniMed Advanced hybrid closed-loop delivery: results from a randomized crossover trial comparing automated insulin delivery with predictive low glucose suspend in people with type 1 diabetes. Diabetes Care. 44:969\u2013975, 2021.","journal-title":"Diabetes Care"},{"key":"3079_CR7","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1089\/dia.2016.0421","volume":"19","author":"SK Garg","year":"2017","unstructured":"Garg, S. K., S. A. Weinzimer, W. V. Tamborlane, et al. Glucose outcomes with the in-home use of a hybrid closed-loop insulin delivery system in adolescents and adults with type 1 diabetes. Diabetes Technol. Ther. 19:155\u2013163, 2017.","journal-title":"Diabetes Technol. Ther."},{"key":"3079_CR8","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1089\/dia.2017.0333","volume":"20","author":"B Grosman","year":"2018","unstructured":"Grosman, B., D. Wu, D. Miller, et al. Sensor-augmented pump-based customized mathematical model for type 1 diabetes. Diabetes Technol. Ther. 20:207\u2013221, 2018.","journal-title":"Diabetes Technol. Ther."},{"key":"3079_CR9","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2021.106087","volume":"205","author":"B Grosman","year":"2021","unstructured":"Grosman, B., D. Wu, N. Parikh, et al. Fast-acting insulin Aspart (Fiasp(R)) improves glycemic outcomes when used with MiniMed(TM) 670G hybrid closed-loop system in simulated trials compared to NovoLog(R). Comput. Methods Programs Biomed.205:106087, 2021.","journal-title":"Comput. Methods Programs Biomed."},{"key":"3079_CR10","doi-asserted-by":"publisher","first-page":"3524","DOI":"10.1109\/TBME.2013.2272736","volume":"60","author":"A Haidar","year":"2013","unstructured":"Haidar, A., M. E. Wilinska, J. A. Graveston, and R. Hovorka. Stochastic virtual population of subjects with type 1 diabetes for the assessment of closed-loop glucose controllers. IEEE Trans. Biomed. Eng. 60:3524\u20133533, 2013.","journal-title":"IEEE Trans. Biomed. Eng."},{"key":"3079_CR11","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1007\/s40262-016-0473-5","volume":"56","author":"T Heise","year":"2017","unstructured":"Heise, T., K. Stender-Petersen, U. Hovelmann, et al. Pharmacokinetic and pharmacodynamic properties of faster-acting insulin Aspart versus insulin Aspart across a clinically relevant dose range in subjects with type 1 diabetes mellitus. Clin. Pharmacokinet. 56:649\u2013660, 2017.","journal-title":"Clin. Pharmacokinet."},{"key":"3079_CR12","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1088\/0967-3334\/25\/4\/010","volume":"25","author":"R Hovorka","year":"2004","unstructured":"Hovorka, R., V. Canonico, L. J. Chassin, et al. Nonlinear model predictive control of glucose concentration in subjects with type 1 diabetes. Physiol. Meas. 25:905\u2013920, 2004.","journal-title":"Physiol. Meas."},{"key":"3079_CR13","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/S0168-8227(00)00151-0","volume":"49","author":"K Kaku","year":"2000","unstructured":"Kaku, K., M. Matsuda, A. Urae, and S. Irie. Pharmacokinetics and pharmacodynamics of insulin Aspart, a rapid-acting analog of human insulin, in healthy Japanese volunteers. Diabetes Res. Clin. Pract. 49:119\u2013126, 2000.","journal-title":"Diabetes Res. Clin. Pract."},{"key":"3079_CR14","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1177\/193229680900300106","volume":"3","author":"BP Kovatchev","year":"2009","unstructured":"Kovatchev, B. P., M. Breton, C. D. Man, and C. Cobelli. In silico preclinical trials: a proof of concept in closed-loop control of type 1 diabetes. J. Diabetes Sci. Technol. 3:44\u201355, 2009.","journal-title":"J. Diabetes Sci. Technol."},{"key":"3079_CR15","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0217301","volume":"14","author":"N Resalat","year":"2019","unstructured":"Resalat, N., J. El Youssef, N. Tyler, J. Castle, and P. G. Jacobs. A statistical virtual patient population for the glucoregulatory system in type 1 diabetes with integrated exercise model. PLoS ONE.14:e0217301, 2019.","journal-title":"PLoS ONE"},{"key":"3079_CR16","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1089\/dia.2013.0377","volume":"16","author":"R Visentin","year":"2014","unstructured":"Visentin, R., C. Dalla Man, B. Kovatchev, and C. Cobelli. The University of Virginia\/Padova type 1 diabetes simulator matches the glucose traces of a clinical trial. Diabetes Technol. Ther. 16:428\u2013434, 2014.","journal-title":"Diabetes Technol. Ther."},{"key":"3079_CR17","doi-asserted-by":"publisher","first-page":"597","DOI":"10.2165\/00003495-199754040-00006","volume":"54","author":"MI Wilde","year":"1997","unstructured":"Wilde, M. I., and D. McTavish. Insulin lispro: a review of its pharmacological properties and therapeutic use in the management of diabetes mellitus. Drugs. 54:597\u2013614, 1997.","journal-title":"Drugs"},{"key":"3079_CR18","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1177\/193229681000400117","volume":"4","author":"ME Wilinska","year":"2010","unstructured":"Wilinska, M. E., L. J. Chassin, C. L. Acerini, J. M. Allen, D. B. Dunger, and R. Hovorka. Simulation environment to evaluate closed-loop insulin delivery systems in type 1 diabetes. J. Diabetes Sci. Technol. 4:132\u2013144, 2010.","journal-title":"J. Diabetes Sci. Technol."}],"container-title":["Annals of Biomedical Engineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10439-022-03079-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10439-022-03079-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10439-022-03079-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,10]],"date-time":"2023-01-10T17:28:07Z","timestamp":1673371687000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10439-022-03079-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,20]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["3079"],"URL":"https:\/\/doi.org\/10.1007\/s10439-022-03079-9","relation":{},"ISSN":["0090-6964","1573-9686"],"issn-type":[{"value":"0090-6964","type":"print"},{"value":"1573-9686","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,20]]},"assertion":[{"value":"10 June 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 September 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 September 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}