{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T05:49:40Z","timestamp":1769147380125,"version":"3.49.0"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T00:00:00Z","timestamp":1711411200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T00:00:00Z","timestamp":1711411200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Biomed Eng"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1007\/s10439-024-03487-z","type":"journal-article","created":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T14:02:17Z","timestamp":1711461737000},"page":"1732-1743","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["An Experimental Phototherapy Device for Studying the Effects of Blue Light on Patients with Raynaud\u2019s Phenomenon"],"prefix":"10.1007","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1182-3438","authenticated-orcid":false,"given":"Brett","family":"Levac","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Kerber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerry A.","family":"Molitor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven S.","family":"Saliterman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,3,26]]},"reference":[{"issue":"2","key":"3487_CR1","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1177\/2397198319826467","volume":"4","author":"AL Herrick","year":"2019","unstructured":"Herrick, A. L. Raynaud\u2019s phenomenon. J. Scleroderm. Relat. Disord. 4:89\u2013101, 2019. https:\/\/doi.org\/10.1177\/2397198319826467.","journal-title":"Journal of Scleroderma and Related Disorders."},{"issue":"6","key":"3487_CR2","doi-asserted-by":"publisher","first-page":"580","DOI":"10.7861\/clinmed.2020-0754","volume":"20","author":"A Haque","year":"2020","unstructured":"Haque, A., and M. Hughes. Raynaud\u2019s phenomenon. Clin. Med. (Northfield Il). 20:580\u2013589, 2020. https:\/\/doi.org\/10.7861\/clinmed.2020-0754.","journal-title":"Clin Med (Northfield Il)."},{"key":"3487_CR3","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.rvm.2016.03.001","volume":"4\u20135","author":"I Silva","year":"2016","unstructured":"Silva, I., G. Teixeira, M. Bert\u00e3o, R. Almeida, A. Mansilha, and C. Vasconcelos. Raynaud phenomenon. Rev. Vasc. Medi 4\u20135:9\u201316, 2016. https:\/\/doi.org\/10.1016\/j.rvm.2016.03.001.","journal-title":"Reviews in Vascular Medicine."},{"key":"3487_CR4","doi-asserted-by":"publisher","DOI":"10.1111\/1754-9485.13293","author":"RZ White","year":"2021","unstructured":"White, R. Z., T. Nguyen, and M. J. Sampson. Magnetic resonance characterisation of primary Raynaud\u2019s phenomenon. J. Med. Imaging Radiat. Oncol. 2021. https:\/\/doi.org\/10.1111\/1754-9485.13293.","journal-title":"J Med Imaging Radiat Oncol."},{"key":"3487_CR5","doi-asserted-by":"publisher","first-page":"101474","DOI":"10.1016\/j.berh.2019.101474","volume":"34","author":"AL Herrick","year":"2020","unstructured":"Herrick, A. L., and F. M. Wigley. Raynaud\u2019s phenomenon. Best Pract. Res. Clin. Rheumatol. 34:101474, 2020. https:\/\/doi.org\/10.1016\/j.berh.2019.101474.","journal-title":"Best Practice & Research in Clinical Rheumatology."},{"issue":"4","key":"3487_CR6","doi-asserted-by":"publisher","first-page":"1611","DOI":"10.1007\/s10067-021-05598-7","volume":"40","author":"SL Murphy","year":"2021","unstructured":"Murphy, S. L., A. Lescoat, M. Alore, et al. How do patients define Raynaud\u2019s phenomenon? Differences between primary and secondary disease. Clin. Rheumatol. 40:1611\u20131616, 2021. https:\/\/doi.org\/10.1007\/s10067-021-05598-7.","journal-title":"Clin Rheumatol."},{"issue":"1","key":"3487_CR7","doi-asserted-by":"publisher","first-page":"145","DOI":"10.26724\/2079-8334-2019-4-70-145-149","volume":"71","author":"OV Shtefiuk","year":"2020","unstructured":"Shtefiuk, O. V., R. I. Yatsyshyn, P. R. Herych, Y. Y. Karpyuk, and V. B. Boychuk. Features of the Raynaud\u2019s syndrome course in patients with rheumatoid arthritis. World Med. Biol. 71:145\u2013149, 2020. https:\/\/doi.org\/10.26724\/2079-8334-2019-4-70-145-149.","journal-title":"World of Medicine and Biology."},{"issue":"11","key":"3487_CR8","doi-asserted-by":"publisher","first-page":"658","DOI":"10.12968\/hmed.2019.80.11.658","volume":"80","author":"V Devgire","year":"2019","unstructured":"Devgire, V., and M. Hughes. Raynaud\u2019s phenomenon. Br. J. Hosp. Med. 80:658\u2013664, 2019. https:\/\/doi.org\/10.12968\/hmed.2019.80.11.658.","journal-title":"Br J Hosp Med."},{"issue":"4","key":"3487_CR9","doi-asserted-by":"publisher","first-page":"201","DOI":"10.5152\/eurjrheum.2020.19211","volume":"7","author":"S Rogers","year":"2020","unstructured":"Rogers, S., and M. Hughes. Digital artery vasospasm in primary Raynaud\u2019s phenomenon. Eur. J. Rheumatol. 7:201\u2013202, 2020. https:\/\/doi.org\/10.5152\/eurjrheum.2020.19211.","journal-title":"European Journal of Rheumatology."},{"key":"3487_CR10","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1186\/s12995-021-00319-x","volume":"16","author":"P Vihlborg","year":"2021","unstructured":"Vihlborg, P., K. Makdomi, H. Gavlovska, S. Wikstrom, and P. Graff. Arterial abnormalities in the hands of workers with vibration white fingers - a magnetic resonance angiography case series. J. Occup. Med. Toxicol. 16:27, 2021. https:\/\/doi.org\/10.1186\/s12995-021-00319-x.","journal-title":"J Occup Med Toxicol."},{"issue":"1","key":"3487_CR11","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1177\/1358863x20983455","volume":"26","author":"E Choi","year":"2021","unstructured":"Choi, E., and S. Henkin. Raynaud\u2019s phenomenon and related vasospastic disorders. Vasc. Med. 26:56\u201370, 2021. https:\/\/doi.org\/10.1177\/1358863x20983455.","journal-title":"Vasc Med."},{"issue":"7","key":"3487_CR12","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1002\/psb.1590","volume":"28","author":"M Hughes","year":"2017","unstructured":"Hughes, M. Assessment and management of Raynaud\u2019s phenomenon. Prescriber. 28:11\u201316, 2017.","journal-title":"Prescriber."},{"issue":"1","key":"3487_CR13","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1080\/23320885.2018.1525684","volume":"5","author":"T Sato","year":"2018","unstructured":"Sato, T., K. Arai, and S. Ichioka. Hyperbaric oxygen therapy for digital ulcers due to Raynaud\u2019s disease. Case Rep. Plast. Surg. Hand Surg. 5:72\u201374, 2018. https:\/\/doi.org\/10.1080\/23320885.2018.1525684.","journal-title":"Case Reports in Plastic Surgery and Hand Surgery."},{"issue":"12","key":"3487_CR14","doi-asserted-by":"publisher","first-page":"3317","DOI":"10.1007\/s10067-019-04745-5","volume":"38","author":"JD Pauling","year":"2019","unstructured":"Pauling, J. D., M. Hughes, and J. E. Pope. Raynaud\u2019s phenomenon-an update on diagnosis, classification and management. Clin. Rheumatol. 38:3317\u20133330, 2019. https:\/\/doi.org\/10.1007\/s10067-019-04745-5.","journal-title":"Clin Rheumatol."},{"key":"3487_CR15","doi-asserted-by":"publisher","DOI":"10.1080\/03009742.2021.1907926","author":"AL Herrick","year":"2021","unstructured":"Herrick, A. L., C. Heal, J. Wilkinson, et al. Temperature response to cold challenge and mobile phone thermography as outcome measures for systemic sclerosis-related Raynaud\u2019s phenomenon. Scand. J. Rheumatol. 2021. https:\/\/doi.org\/10.1080\/03009742.2021.1907926.","journal-title":"Scand J Rheumatol."},{"issue":"9","key":"3487_CR16","doi-asserted-by":"publisher","first-page":"2410","DOI":"10.1002\/art.10486","volume":"46","author":"PA Merkel","year":"2002","unstructured":"Merkel, P. A., K. Herlyn, R. W. Martin, et al. Measuring disease activity and functional status in patients with scleroderma and Raynaud\u2019s phenomenon. Arthritis Rheum. 46:2410\u20132420, 2002. https:\/\/doi.org\/10.1002\/art.10486.","journal-title":"Arthritis Rheum."},{"issue":"1","key":"3487_CR17","doi-asserted-by":"publisher","first-page":"90","DOI":"10.5507\/bp.2020.031","volume":"165","author":"J Sternbersky","year":"2021","unstructured":"Sternbersky, J., M. Tichy, and J. Zapletalova. Infrared thermography and capillaroscopy in the diagnosis of Raynaud\u2019s phenomenon. Biomed. Papers-Olomouc. 165:90\u201398, 2021. https:\/\/doi.org\/10.5507\/bp.2020.031.","journal-title":"Biomedical Papers-Olomouc."},{"key":"3487_CR18","doi-asserted-by":"publisher","first-page":"981","DOI":"10.3390\/diagnostics11060981","volume":"11","author":"L Lindberg","year":"2021","unstructured":"Lindberg, L., B. Kristensen, E. Eldrup, J. F. Thomsen, and L. T. Jensen. Infrared thermography as a method of verification in Raynaud\u2019s phenomenon. Diagnostics. 11:981, 2021. https:\/\/doi.org\/10.3390\/diagnostics11060981.","journal-title":"Diagnostics."},{"key":"3487_CR19","doi-asserted-by":"publisher","first-page":"558","DOI":"10.3390\/diagnostics11030558","volume":"11","author":"L Lindberg","year":"2021","unstructured":"Lindberg, L., B. Kristensen, J. F. Thomsen, E. Eldrup, and L. T. Jensen. Characteristic features of infrared thermographic imaging in primary Raynaud\u2019s phenomenon. Diagnostics. 11:558, 2021. https:\/\/doi.org\/10.3390\/diagnostics11030558.","journal-title":"Diagnostics."},{"key":"3487_CR20","doi-asserted-by":"publisher","DOI":"10.1111\/srt.13070","author":"T Aleksiev","year":"2021","unstructured":"Aleksiev, T., Z. Ivanova, H. Dobrev, and N. Atanasov. Application of a novel finger temperature device in the assessment of subjects with Raynaud\u2019s phenomenon. Skin Res. Technol. 2021. https:\/\/doi.org\/10.1111\/srt.13070.","journal-title":"Skin Research and Technology."},{"issue":"4","key":"3487_CR21","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1080\/03009742.2017.1397187","volume":"47","author":"C Rotondo","year":"2018","unstructured":"Rotondo, C., M. Nivuori, A. Chial\u00e0, et al. Evidence for increase in finger blood flow, evaluated by laser Doppler flowmetry, following iloprost infusion in patients with systemic sclerosis: a week-long observational longitudinal study. Scand. J. Rheumatol. 47:311\u2013318, 2018. https:\/\/doi.org\/10.1080\/03009742.2017.1397187.","journal-title":"Scand J Rheumatol."},{"issue":"3","key":"3487_CR22","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1080\/09546634.2018.1484875","volume":"30","author":"M Hughes","year":"2019","unstructured":"Hughes, M., T. Moore, J. Manning, et al. A feasibility study of a novel low-level light therapy for digital ulcers in systemic sclerosis. J. Dermatol. Treat. 30:251\u2013257, 2019. https:\/\/doi.org\/10.1080\/09546634.2018.1484875.","journal-title":"J Dermatolog Treat."},{"issue":"1","key":"3487_CR23","doi-asserted-by":"publisher","first-page":"5","DOI":"10.2174\/1573397113666170615084229","volume":"14","author":"F Ingegnoli","year":"2018","unstructured":"Ingegnoli, F., V. Smith, A. Sulli, and M. Cutolo. Capillaroscopy in routine diagnostics: potentials and limitations. Curr. Rheumatol. Rev. 14:5\u201311, 2018. https:\/\/doi.org\/10.2174\/1573397113666170615084229.","journal-title":"Curr. Rheumatol. Rev."},{"issue":"5","key":"3487_CR24","doi-asserted-by":"publisher","first-page":"2054","DOI":"10.1093\/rheumatology\/keab006","volume":"60","author":"AL Herrick","year":"2021","unstructured":"Herrick, A. L., M. Berks, and C. J. Taylor. Quantitative nailfold capillaroscopy-update and possible next steps. Rheumatology. 60:2054\u20132065, 2021. https:\/\/doi.org\/10.1093\/rheumatology\/keab006.","journal-title":"Rheumatology."},{"key":"3487_CR25","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD006687.pub4","author":"KYC Su","year":"2021","unstructured":"Su, K. Y. C., M. Sharma, H. J. Kim, et al. Vasodilators for primary Raynaud\u2019s phenomenon. Cochrane Database Syst Rev. 2021. https:\/\/doi.org\/10.1002\/14651858.CD006687.pub4.","journal-title":"Cochrane Database Syst Rev."},{"issue":"2","key":"3487_CR26","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1093\/rheumatology\/keh390","volume":"44","author":"AE Thompson","year":"2005","unstructured":"Thompson, A. E., and J. E. Pope. Calcium channel blockers for primary Raynaud\u2019s phenomenon: a meta-analysis. Rheumatology. 44:145\u2013150, 2005. https:\/\/doi.org\/10.1093\/rheumatology\/keh390.","journal-title":"Rheumatology."},{"issue":"6","key":"3487_CR27","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1056\/NEJMra1507638","volume":"375","author":"FM Wigley","year":"2016","unstructured":"Wigley, F. M., and N. A. Flavahan. Raynaud\u2019s phenomenon. N Engl. J. Ed. 375:556\u2013565, 2016. https:\/\/doi.org\/10.1056\/NEJMra1507638.","journal-title":"N Engl. J. Ed."},{"key":"3487_CR28","doi-asserted-by":"publisher","first-page":"377","DOI":"10.3390\/ma14020377","volume":"14","author":"HW Dawit","year":"2021","unstructured":"Dawit, H. W., Q. Zhang, Y. M. Li, S. R. Islam, J. F. Mao, and L. Wang. Design of electro-thermal glove with sensor function for Raynaud\u2019s phenomenon patients. Materials. 14:377, 2021. https:\/\/doi.org\/10.3390\/ma14020377.","journal-title":"Materials."},{"key":"3487_CR29","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1136\/annrheumdis-2020-eular.443","volume":"79","author":"N Azuma","year":"2020","unstructured":"Azuma, N., T. Furukawa, Y. Shima, and K. Matsui. A usability survey of wrist mounted disposable heat pad on Raynaud\u2019s phenomenon in patients with connective tissue diseases. Ann Rheum Dis. 79:692\u2013693, 2020. https:\/\/doi.org\/10.1136\/annrheumdis-2020-eular.443.","journal-title":"Ann Rheum Dis."},{"issue":"50","key":"3487_CR30","doi-asserted-by":"publisher","first-page":"17977","DOI":"10.1073\/pnas.1420258111","volume":"111","author":"G Sikka","year":"2014","unstructured":"Sikka, G., G. P. Hussmann, D. Pandey, et al. Melanopsin mediates light-dependent relaxation in blood vessels. Proc. Natl. Acad. Sci. USA 111:17977\u201317982, 2014. https:\/\/doi.org\/10.1073\/pnas.1420258111.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America."},{"issue":"1","key":"3487_CR31","doi-asserted-by":"publisher","first-page":"L93","DOI":"10.1152\/ajplung.00091.2017","volume":"314","author":"SB Ortiz","year":"2018","unstructured":"Ortiz, S. B., D. Hori, Y. Nomura, et al. Opsin 3 and 4 mediate light-induced pulmonary vasorelaxation that is potentiated by G protein-coupled receptor kinase 2 inhibition. Am. J. Physiol. 314:L93\u2013L106, 2018. https:\/\/doi.org\/10.1152\/ajplung.00091.2017.","journal-title":"American Journal of Physiology-Lung Cellular and Molecular Physiology."},{"issue":"1","key":"3487_CR32","doi-asserted-by":"publisher","first-page":"14","DOI":"10.4103\/jfmpc.jfmpc_375_18","volume":"8","author":"P Modi","year":"2019","unstructured":"Modi, P., K. Jha, Y. Kumar, T. Kumar, R. Singh, and A. Mishra. The effect of short-term exposure to red and blue light on the autonomic tone of the individuals with newly diagnosed essential hypertension. J. Fam. Med. Primary Care. 8:14\u201321, 2019. https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_375_18.","journal-title":"Journal of Family Medicine & Primary Care."},{"key":"3487_CR33","doi-asserted-by":"publisher","unstructured":"Stern, M., M. Broja, R. Sansone, et al. Blue light exposure decreases systolic blood pressure, arterial stiffness, and improves endothelial function in humans. Randomized Controlled Trial Research Support, Non-U.S. Gov't. Eur. J. Prevent. Cardiol.. 25:1875\u20131883,  2018. doi:https:\/\/doi.org\/10.1177\/2047487318800072","DOI":"10.1177\/2047487318800072"},{"issue":"2","key":"3487_CR34","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.anpedi.2019.02.008","volume":"92","author":"A Montealegre","year":"2020","unstructured":"Montealegre, A., N. Charpak, A. Parra, C. Devia, I. Coca, and A. M. Bertolotto. Effectiveness and safety of two phototherapy devices for the humanised management of neonatal jaundice. Anal\u00a0Pediatr. 92:79\u201387, 2020. https:\/\/doi.org\/10.1016\/j.anpedi.2019.02.008.","journal-title":"Anal\u00a0Pediatr."},{"key":"3487_CR35","doi-asserted-by":"publisher","first-page":"088001","DOI":"10.1117\/1.Jbo.17.8.088001","volume":"17","author":"BC Liu","year":"2012","unstructured":"Liu, B. C., T. J. Farrell, and M. S. Patterson. Comparison of photodynamic therapy with different excitation wavelengths using a dynamic model of aminolevulinic acid-photodynamic therapy of human skin. J. Biomed. Opt. 17:088001, 2012. https:\/\/doi.org\/10.1117\/1.Jbo.17.8.088001.","journal-title":"J. Biomed. Opt."},{"key":"3487_CR36","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1111\/j.1468-3083.2011.04039.x","volume":"26","author":"MM Kleinpenning","year":"2012","unstructured":"Kleinpenning, M. M., M. E. Otero, P. E. J. van Erp, M. J. P. Gerritsen, and P. C. M. van de Kerkhof. Efficacy of blue light vs. red light in the treatment of psoriasis: a double-blind, randomized comparative study. J Eur Acad Dermatol Venereol. 26:219\u2013225, 2012. https:\/\/doi.org\/10.1111\/j.1468-3083.2011.04039.x.","journal-title":"J Eur Acad Dermatol Venereol."},{"key":"3487_CR37","doi-asserted-by":"crossref","unstructured":"Keemss. Prospective, randomized study on the efficacy and safety of local UV-free blue light treatment of eczema (vol 232, pg 496, 2016). Dermatology. 232:522\u2013522, 2016.","DOI":"10.1159\/000448000"},{"key":"3487_CR38","doi-asserted-by":"publisher","first-page":"191","DOI":"10.18240\/ijo.2017.02.03","volume":"10","author":"YM Shang","year":"2017","unstructured":"Shang, Y. M., G. S. Wang, D. H. Sliney, C. H. Yang, and L. L. Lee. Light-emitting-diode induced retinal damage and its wavelength dependency in vivo. Int. J. Ophthalmol. 10:191\u2013202, 2017. https:\/\/doi.org\/10.18240\/ijo.2017.02.03.","journal-title":"Int. J. Ophthalmol."},{"issue":"11","key":"3487_CR39","doi-asserted-by":"publisher","first-page":"2141","DOI":"10.1364\/josaa.7.002141","volume":"7","author":"JM Schmitt","year":"1990","unstructured":"Schmitt, J. M., G. X. Zhou, E. C. Walker, and R. T. Wall. Multilayer model of photon diffusion in skin. J. Opt. Soc. Am. A. 7:2141\u20132153, 1990. https:\/\/doi.org\/10.1364\/josaa.7.002141.","journal-title":"J. Opt. Soc. Am. A."},{"issue":"5","key":"3487_CR40","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1134\/s0030400x13110167","volume":"115","author":"SA Lisenko","year":"2013","unstructured":"Lisenko, S. A., M. M. Kugeiko, and A. M. Lisenkova. Noninvasive determination of spectral depth of light penetration into skin. OptSp. 115:779\u2013785, 2013. https:\/\/doi.org\/10.1134\/s0030400x13110167.","journal-title":"OptSp."},{"issue":"10","key":"3487_CR41","doi-asserted-by":"publisher","first-page":"4220","DOI":"10.1364\/BOE.7.004220","volume":"7","author":"M Kim","year":"2016","unstructured":"Kim, M., J. An, K. S. Kim, et al. Optical lens-microneedle array for percutaneous light delivery. Biomed. Opt. Express. 7:4220\u20134227, 2016. https:\/\/doi.org\/10.1364\/BOE.7.004220.","journal-title":"Biomed. Opt. Express."},{"issue":"1","key":"3487_CR42","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1038\/jid.2009.19","volume":"130","author":"J Liebmann","year":"2010","unstructured":"Liebmann, J., M. Born, and V. Kolb-Bachofen. Blue-light irradiation regulates proliferation and differentiation in human skin cells. J. Invest. Dermatol. 130:259\u2013269, 2010. https:\/\/doi.org\/10.1038\/jid.2009.19.","journal-title":"J. Invest. Dermatol."},{"key":"3487_CR43","doi-asserted-by":"publisher","first-page":"e1500701","DOI":"10.1126\/sciadv.1500701","volume":"1","author":"RC Webb","year":"2015","unstructured":"Webb, R. C., Y. J. Ma, S. Krishnan, et al. Epidermal devices for noninvasive, precise, and continuous mapping of macrovascular and microvascular blood flow. Sci. Adv. 1:e1500701, 2015. https:\/\/doi.org\/10.1126\/sciadv.1500701.","journal-title":"Sci. Adv."},{"issue":"5","key":"3487_CR44","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1007\/s11517-007-0170-5","volume":"45","author":"A Humeau","year":"2007","unstructured":"Humeau, A., W. Steenbergen, H. Nilsson, and T. Stromberg. Laser Doppler perfusion monitoring and imaging: novel approaches. Med Biol Eng Comput. 45:421\u2013435, 2007. https:\/\/doi.org\/10.1007\/s11517-007-0170-5.","journal-title":"Med Biol Eng Comput."},{"key":"3487_CR45","doi-asserted-by":"crossref","unstructured":"Nogami, H., K. Komatsutani, T. Hirata and R. Sawada. IEEE TPC. Integrated laser Doppler blood flowmeter combining optical contact force, pp. 287\u2013290, 2019.","DOI":"10.23919\/ICEP.2019.8733508"}],"container-title":["Annals of Biomedical Engineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10439-024-03487-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10439-024-03487-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10439-024-03487-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T17:11:44Z","timestamp":1715274704000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10439-024-03487-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,26]]},"references-count":45,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["3487"],"URL":"https:\/\/doi.org\/10.1007\/s10439-024-03487-z","relation":{},"ISSN":["0090-6964","1573-9686"],"issn-type":[{"value":"0090-6964","type":"print"},{"value":"1573-9686","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,26]]},"assertion":[{"value":"25 October 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 February 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 March 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"On January 9, 2024 the authors and the University of Minnesota received a patent (U.S. 11,865,357) for the PTD and various methods for translating the technology into useful solutions for patients (both stationary and wearable systems).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosures"}}]}}