{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T19:17:54Z","timestamp":1791487074591,"version":"4.3.4"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T00:00:00Z","timestamp":1774224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T00:00:00Z","timestamp":1774224000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100002661","name":"Fonds De La Recherche Scientifique - FNRS","doi-asserted-by":"publisher","award":["J.0057.22"],"award-info":[{"award-number":["J.0057.22"]}],"id":[{"id":"10.13039\/501100002661","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002661","name":"Fonds De La Recherche Scientifique - FNRS","doi-asserted-by":"publisher","award":["FC 46825"],"award-info":[{"award-number":["FC 46825"]}],"id":[{"id":"10.13039\/501100002661","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002661","name":"Fonds De La Recherche Scientifique - FNRS","doi-asserted-by":"publisher","award":["7.4505.25"],"award-info":[{"award-number":["7.4505.25"]}],"id":[{"id":"10.13039\/501100002661","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017653","name":"Fonds Sp\u00e9ciaux de Recherche","doi-asserted-by":"publisher","award":["IRECFSR23MOVEAND"],"award-info":[{"award-number":["IRECFSR23MOVEAND"]}],"id":[{"id":"10.13039\/501100017653","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011068","name":"Fondation Saint Luc","doi-asserted-by":"publisher","award":["Fetus for Life"],"award-info":[{"award-number":["Fetus for Life"]}],"id":[{"id":"10.13039\/501100011068","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002910","name":"F\u00e9d\u00e9ration Wallonie-Bruxelles","doi-asserted-by":"publisher","award":["24\/29-137"],"award-info":[{"award-number":["24\/29-137"]}],"id":[{"id":"10.13039\/501100002910","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010890","name":"Chinese Government Scholarship","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010890","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Biomed Eng"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1007\/s10439-026-04105-w","type":"journal-article","created":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T14:43:10Z","timestamp":1774276990000},"page":"3515-3530","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparative Analysis of Decellularization Protocols for Human Placenta: Balancing Cell Removal with Extracellular Matrix Preservation for Hydrogel Applications"],"prefix":"10.1007","volume":"54","author":[{"given":"Saba","family":"Nikanfar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunran","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saeid","family":"Moghassemi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur","family":"Colson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hafez","family":"Jafari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armin","family":"Shavandi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Wyns","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Debi\u00e8ve","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1794-0368","authenticated-orcid":false,"given":"Christiani A.","family":"Amorim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,23]]},"reference":[{"issue":"7","key":"4105_CR1","doi-asserted-by":"publisher","first-page":"579","DOI":"10.3390\/biology10070579","volume":"10","author":"F Re","year":"2021","unstructured":"Re, F., et al. Bone regeneration improves with mesenchymal stem cell derived extracellular vesicles (EVs) combined with scaffolds: a systematic review. Biology. 10(7):579, 2021.","journal-title":"Biology."},{"key":"4105_CR2","doi-asserted-by":"publisher","first-page":"9831534","DOI":"10.1155\/2017\/9831534","volume":"2017","author":"A Gilpin","year":"2017","unstructured":"Gilpin, A., and Y. Yang. Decellularization strategies for regenerative medicine: from processing techniques to applications. Biomed. Res. Int. 2017:9831534, 2017.","journal-title":"Biomed. Res. Int."},{"issue":"44","key":"4105_CR3","doi-asserted-by":"publisher","first-page":"10023","DOI":"10.1039\/D0TB01534B","volume":"8","author":"J Liao","year":"2020","unstructured":"Liao, J., et al. Applications of decellularized materials in tissue engineering: advantages, drawbacks and current improvements, and future perspectives. J. Mater. Chem. B. 8(44):10023\u201310049, 2020.","journal-title":"J. Mater. Chem. B."},{"key":"4105_CR4","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2020.610544","volume":"8","author":"AR Silini","year":"2020","unstructured":"Silini, A. R., et al. Perinatal derivatives: where do we stand? A roadmap of the human placenta and consensus for tissue and cell nomenclature. Front. Bioeng. Biotechnol.8:610544, 2020.","journal-title":"Front. Bioeng. Biotechnol."},{"issue":"1","key":"4105_CR5","doi-asserted-by":"publisher","DOI":"10.1590\/1414-431x20176382","volume":"51","author":"L Leonel","year":"2017","unstructured":"Leonel, L., et al. Decellularization of placentas: establishing a protocol. Braz. J. Med. Biol. Res.51(1):e6382, 2017.","journal-title":"Braz. J. Med. Biol. Res."},{"key":"4105_CR6","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1016\/j.bioactmat.2025.03.011","volume":"49","author":"S Moghassemi","year":"2025","unstructured":"Moghassemi, S., et al. The revolutionary role of placental derivatives in biomedical research. Bioactive Mater. 49:456\u2013485, 2025.","journal-title":"Bioactive Mater."},{"key":"4105_CR7","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.actbio.2020.12.055","volume":"122","author":"C Wang","year":"2021","unstructured":"Wang, C., et al. Sulfated glycosaminoglycans in decellularized placenta matrix as critical regulators for cutaneous wound healing. Acta Biomater. 122:199\u2013210, 2021.","journal-title":"Acta Biomater."},{"key":"4105_CR8","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/j.actbio.2016.12.027","volume":"52","author":"MP Francis","year":"2017","unstructured":"Francis, M. P., et al. Human placenta hydrogel reduces scarring in a rat model of cardiac ischemia and enhances cardiomyocyte and stem cell cultures. Acta Biomater. 52:92\u2013104, 2017.","journal-title":"Acta Biomater."},{"issue":"5","key":"4105_CR9","doi-asserted-by":"publisher","first-page":"3218","DOI":"10.1021\/acsbiomaterials.4c00067","volume":"10","author":"Z Wang","year":"2024","unstructured":"Wang, Z., et al. Human placenta decellularized extracellular matrix hydrogel promotes the generation of human spinal cord organoids with dorsoventral organization from human induced pluripotent stem cells. ACS Biomater. Sci. Eng. 10(5):3218\u20133231, 2024.","journal-title":"ACS Biomater. Sci. Eng."},{"key":"4105_CR10","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.jmbbm.2011.12.003","volume":"8","author":"WS Sheridan","year":"2012","unstructured":"Sheridan, W. S., G. P. Duffy, and B. P. Murphy. Mechanical characterization of a customized decellularized scaffold for vascular tissue engineering. J. Mech. Behav. Biomed. Mater. 8:58\u201370, 2012.","journal-title":"J. Mech. Behav. Biomed. Mater."},{"issue":"33","key":"4105_CR11","doi-asserted-by":"publisher","first-page":"8626","DOI":"10.1016\/j.biomaterials.2010.07.083","volume":"31","author":"JE Reing","year":"2010","unstructured":"Reing, J. E., et al. The effects of processing methods upon mechanical and biologic properties of porcine dermal extracellular matrix scaffolds. Biomaterials. 31(33):8626\u20138633, 2010.","journal-title":"Biomaterials."},{"issue":"26","key":"4105_CR12","doi-asserted-by":"publisher","first-page":"6738","DOI":"10.1016\/j.biomaterials.2010.05.020","volume":"31","author":"JS Choi","year":"2010","unstructured":"Choi, J. S., et al. Bioengineering endothelialized neo-corneas using donor-derived corneal endothelial cells and decellularized corneal stroma. Biomaterials. 31(26):6738\u20136745, 2010.","journal-title":"Biomaterials."},{"issue":"9","key":"4105_CR13","doi-asserted-by":"publisher","first-page":"2549","DOI":"10.1016\/j.biomaterials.2009.11.088","volume":"31","author":"J Zhou","year":"2010","unstructured":"Zhou, J., et al. Impact of heart valve decellularization on 3-D ultrastructure, immunogenicity and thrombogenicity. Biomaterials. 31(9):2549\u20132554, 2010.","journal-title":"Biomaterials."},{"issue":"5","key":"4105_CR14","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1007\/s10856-021-06517-7","volume":"32","author":"F Asgari","year":"2021","unstructured":"Asgari, F., et al. Optimization of decellularized human placental macroporous scaffolds for spermatogonial stem cells homing. J. Mater. Sci. Mater. Med. 32(5):47, 2021.","journal-title":"J. Mater. Sci. Mater. Med."},{"issue":"1","key":"4105_CR15","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/s13287-020-02066-y","volume":"12","author":"Y Jiang","year":"2021","unstructured":"Jiang, Y., et al. Myocardial repair of bioengineered cardiac patches with decellularized placental scaffold and human-induced pluripotent stem cells in a rat model of myocardial infarction. Stem Cell. Res. Ther. 12(1):13, 2021.","journal-title":"Stem Cell. Res. Ther."},{"key":"4105_CR16","doi-asserted-by":"publisher","first-page":"204173141986796","DOI":"10.1177\/2041731419867962","volume":"10","author":"RS Barreto","year":"2019","unstructured":"Barreto, R. S., et al. Mouse placental scaffolds: a three-dimensional environment model for recellularization. J. Tissue Eng. 10:2041731419867962, 2019.","journal-title":"J. Tissue Eng."},{"key":"4105_CR17","doi-asserted-by":"publisher","first-page":"3935","DOI":"10.1038\/ncomms4935","volume":"5","author":"F Pati","year":"2014","unstructured":"Pati, F., et al. Printing three-dimensional tissue analogues with decellularized extracellular matrix bioink. Nat. Commun. 5:3935, 2014.","journal-title":"Nat. Commun."},{"issue":"3","key":"4105_CR18","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/pharmaceutics16030430","volume":"16","author":"C Xie","year":"2024","unstructured":"Xie, C., et al. Synthesis and properties of injectable hydrogel for tissue filling. Pharmaceutics. 16(3):1, 2024.","journal-title":"Pharmaceutics."},{"key":"4105_CR19","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.ymeth.2015.03.024","volume":"84","author":"JL Ungerleider","year":"2015","unstructured":"Ungerleider, J. L., et al. Fabrication and characterization of injectable hydrogels derived from decellularized skeletal and cardiac muscle. Methods. 84:53\u201359, 2015.","journal-title":"Methods."},{"key":"4105_CR20","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1016\/j.actbio.2018.04.001","volume":"73","author":"T Lin","year":"2018","unstructured":"Lin, T., et al. Hydrogel derived from porcine decellularized nerve tissue as a promising biomaterial for repairing peripheral nerve defects. Acta Biomater. 73:326\u2013338, 2018.","journal-title":"Acta Biomater."},{"issue":"11","key":"4105_CR21","doi-asserted-by":"publisher","first-page":"15222","DOI":"10.1096\/fj.202001681R","volume":"34","author":"A Colson","year":"2020","unstructured":"Colson, A., et al. Hypoxia-inducible factor 2 alpha impairs human cytotrophoblast syncytialization: new insights into placental dysfunction and fetal growth restriction. Faseb J. 34(11):15222\u201315235, 2020.","journal-title":"Faseb J."},{"issue":"19","key":"4105_CR22","doi-asserted-by":"publisher","DOI":"10.21769\/BioProtoc.4185","volume":"11","author":"A Colson","year":"2021","unstructured":"Colson, A., et al. Isolation of primary cytotrophoblasts from human placenta at term. Bio. Protoc.11(19):e4185, 2021.","journal-title":"Bio. Protoc."},{"key":"4105_CR23","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2025.117778","volume":"252","author":"C Mart\u00ednez-L\u00f3pez","year":"2026","unstructured":"Mart\u00ednez-L\u00f3pez, C., et al. Extracellular matrix properties of porcine reproductive scaffolds depend on storage temperature. Theriogenology.252:117778, 2026.","journal-title":"Theriogenology."},{"key":"4105_CR24","doi-asserted-by":"publisher","first-page":"1621641","DOI":"10.3389\/fbioe.2025.1621641","volume":"13","author":"OI Shevchuk","year":"2025","unstructured":"Shevchuk, O. I., et al. Application of decellularization methods for scaffold production: advantages, disadvantages, biosafety and modifications. Front. Bioeng. Biotechnol. 13:1621641, 2025.","journal-title":"Front. Bioeng. Biotechnol."},{"key":"4105_CR25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2024.105347","volume":"311","author":"CM Le\u00f3n-F\u00e9lix","year":"2025","unstructured":"Le\u00f3n-F\u00e9lix, C. M., et al. Decellularized extracellular matrix from bovine ovarian tissue maintains the protein composition of the native matrisome. J. Proteomics.311:105347, 2025.","journal-title":"J. Proteomics."},{"issue":"4","key":"4105_CR26","doi-asserted-by":"publisher","first-page":"1222","DOI":"10.1016\/j.transproceed.2014.09.181","volume":"47","author":"A Kakabadze","year":"2015","unstructured":"Kakabadze, A., and Z. Kakabadze. Prospect of using decellularized human placenta and cow placentome for creation of new organs: targeting the liver (part I: anatomic study). Transplant. Proc. 47(4):1222\u20131227, 2015.","journal-title":"Transplant. Proc."},{"key":"4105_CR27","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1016\/j.actbio.2022.12.003","volume":"157","author":"SC Kellaway","year":"2023","unstructured":"Kellaway, S. C., et al. Engineered neural tissue made using hydrogels derived from decellularised tissues for the regeneration of peripheral nerves. Acta Biomater. 157:124\u2013136, 2023.","journal-title":"Acta Biomater."},{"issue":"12","key":"4105_CR28","doi-asserted-by":"publisher","first-page":"3233","DOI":"10.1016\/j.biomaterials.2011.01.057","volume":"32","author":"PM Crapo","year":"2011","unstructured":"Crapo, P. M., T. W. Gilbert, and S. F. Badylak. An overview of tissue and whole organ decellularization processes. Biomaterials. 32(12):3233\u20133243, 2011.","journal-title":"Biomaterials."},{"issue":"3 Pt 2","key":"4105_CR29","first-page":"H1007","volume":"266","author":"DA MacKenna","year":"1994","unstructured":"MacKenna, D. A., et al. Contribution of collagen matrix to passive left ventricular mechanics in isolated rat hearts. Am. J. Physiol. 266(3 Pt 2):H1007\u2013H1018, 1994.","journal-title":"Am. J. Physiol."},{"key":"4105_CR30","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/j.biomaterials.2015.05.015","volume":"61","author":"NA Hotaling","year":"2015","unstructured":"Hotaling, N. A., et al. DiameterJ: a validated open source nanofiber diameter measurement tool. Biomaterials. 61:327\u2013338, 2015.","journal-title":"Biomaterials."},{"issue":"1","key":"4105_CR31","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1007\/s10237-016-0811-4","volume":"16","author":"JM Mattson","year":"2017","unstructured":"Mattson, J. M., R. Turcotte, and Y. Zhang. Glycosaminoglycans contribute to extracellular matrix fiber recruitment and arterial wall mechanics. Biomech. Model Mechanobiol. 16(1):213\u2013225, 2017.","journal-title":"Biomech. Model Mechanobiol."},{"issue":"10","key":"4105_CR32","doi-asserted-by":"publisher","first-page":"1237","DOI":"10.1016\/j.joca.2008.02.014","volume":"16","author":"E Pfeiffer","year":"2008","unstructured":"Pfeiffer, E., et al. The effects of glycosaminoglycan content on the compressive modulus of cartilage engineered in type II collagen scaffolds. Osteoarthritis Cartilage. 16(10):1237\u20131244, 2008.","journal-title":"Osteoarthritis Cartilage."},{"key":"4105_CR33","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.biologicals.2017.05.008","volume":"48","author":"B Nasiri","year":"2017","unstructured":"Nasiri, B., and S. Mashayekhan. Fabrication of porous scaffolds with decellularized cartilage matrix for tissue engineering application. Biologicals. 48:39\u201346, 2017.","journal-title":"Biologicals."},{"issue":"1","key":"4105_CR34","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1089\/ten.tec.2013.0666","volume":"21","author":"Q Xing","year":"2015","unstructured":"Xing, Q., et al. Decellularization of fibroblast cell sheets for natural extracellular matrix scaffold preparation. Tissue Eng. C Methods. 21(1):77\u201387, 2015.","journal-title":"Tissue Eng. C Methods."},{"issue":"1\u20132","key":"4105_CR35","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1089\/ten.tea.2014.0095","volume":"21","author":"CA Carruthers","year":"2015","unstructured":"Carruthers, C. A., et al. Histologic characterization of acellular dermal matrices in a porcine model of tissue expander breast reconstruction. Tissue Eng. A. 21(1\u20132):35\u201344, 2015.","journal-title":"Tissue Eng. A."},{"issue":"6616","key":"4105_CR36","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1126\/science.abo7935","volume":"378","author":"M Sykes","year":"2022","unstructured":"Sykes, M. Developing pig-to-human organ transplants. Science. 378(6616):135\u2013136, 2022.","journal-title":"Science."},{"issue":"2","key":"4105_CR37","volume":"93","author":"G Gullo","year":"2022","unstructured":"Gullo, G., et al. The reproductive potential of uterus transplantation: future prospects. Acta Biomed.93(2):e2022138, 2022.","journal-title":"Acta Biomed."},{"issue":"2","key":"4105_CR38","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1002\/ijgo.14052","volume":"157","author":"K Tahermanesh","year":"2022","unstructured":"Tahermanesh, K., et al. Hourglass cesarean scar: a neglected external niche in association with the internal niche. Int. J. Gynecol. Obstet. 157(2):478\u2013480, 2022.","journal-title":"Int. J. Gynecol. Obstet."},{"issue":"1","key":"4105_CR39","doi-asserted-by":"publisher","first-page":"2","DOI":"10.3390\/ijms19010227","volume":"19","author":"M Vermeulen","year":"2018","unstructured":"Vermeulen, M., et al. Development of a cytocompatible scaffold from pig immature testicular tissue allowing human sertoli cell attachment, proliferation and functionality. Int. J. Mol. Sci. 19(1):2, 2018.","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"4105_CR40","doi-asserted-by":"publisher","first-page":"21545","DOI":"10.1038\/s41598-024-71973-4","volume":"14","author":"MH Khosropanah","year":"2024","unstructured":"Khosropanah, M. H., et al. Efficient decellularization of human fetal kidneys through optimized SDS exposure. Sci. Rep. 14(1):21545, 2024.","journal-title":"Sci. Rep."},{"key":"4105_CR41","doi-asserted-by":"publisher","DOI":"10.1590\/1414-431x2024e13107","volume":"57","author":"M Mantovani","year":"2024","unstructured":"Mantovani, M., et al. Which detergent is most suitable for the generation of an acellular pancreas bioscaffold? Braz. J. Med. Biol. Res.57:e13107, 2024.","journal-title":"Braz. J. Med. Biol. Res."},{"issue":"3","key":"4105_CR42","doi-asserted-by":"publisher","first-page":"1241","DOI":"10.1016\/j.actbio.2010.11.017","volume":"7","author":"B Mendoza-Novelo","year":"2011","unstructured":"Mendoza-Novelo, B., et al. Decellularization of pericardial tissue and its impact on tensile viscoelasticity and glycosaminoglycan content. Acta Biomater. 7(3):1241\u20131248, 2011.","journal-title":"Acta Biomater."},{"key":"4105_CR43","doi-asserted-by":"publisher","first-page":"1418034","DOI":"10.3389\/fbioe.2024.1418034","volume":"12","author":"A Fazel Anvari Yazdi","year":"2024","unstructured":"Fazel Anvari Yazdi, A., et al. Comparative analysis of porcine-uterine decellularization for bioactive-molecule preservation and DNA removal. Front. Bioeng. Biotechnol. 12:1418034, 2024.","journal-title":"Front. Bioeng. Biotechnol."}],"container-title":["Annals of Biomedical Engineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10439-026-04105-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10439-026-04105-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10439-026-04105-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T18:25:23Z","timestamp":1791483923000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10439-026-04105-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,23]]},"references-count":43,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["4105"],"URL":"https:\/\/doi.org\/10.1007\/s10439-026-04105-w","relation":{},"ISSN":["0090-6964","1573-9686"],"issn-type":[{"value":"0090-6964","type":"print"},{"value":"1573-9686","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,23]]},"assertion":[{"value":"16 November 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}]}}