{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T20:51:25Z","timestamp":1757623885880,"version":"3.44.0"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T00:00:00Z","timestamp":1754956800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T00:00:00Z","timestamp":1754956800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Acta Biotheor"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1007\/s10441-025-09501-8","type":"journal-article","created":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T17:48:08Z","timestamp":1755020888000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessment of the Efficiency of Vaccination and Short-term Isolation in Lowering the Disease Load in Koalas Population"],"prefix":"10.1007","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3646-0768","authenticated-orcid":false,"given":"Parimita","family":"Roy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjoli","family":"Jain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ranjit Kumar","family":"Upadhyay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ani","family":"Jain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,8,12]]},"reference":[{"issue":"3","key":"9501_CR1","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1016\/S0022-5193(89)80211-5","volume":"139","author":"R Arditi","year":"1989","unstructured":"Arditi R, Ginzburg LR (1989) Coupling in predator-prey dynamics: Ratio-dependence. J Theor Biol 139(3):311\u2013326. https:\/\/doi.org\/10.1016\/S0022-5193(89)80211-5","journal-title":"J Theor Biol"},{"issue":"2","key":"9501_CR2","doi-asserted-by":"publisher","first-page":"913","DOI":"10.1088\/0951-7715\/18\/2\/022","volume":"18","author":"M Bandyopadhyay","year":"2005","unstructured":"Bandyopadhyay M, Chattopadhyay J (2005) Ratio-dependent predator-prey model: Effect of environmental fluctuation and stability. Nonlinearity 18(2):913\u2013936. https:\/\/doi.org\/10.1088\/0951-7715\/18\/2\/022","journal-title":"Nonlinearity"},{"issue":"02","key":"9501_CR3","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1142\/S0218339003000816","volume":"11","author":"M Bandyopadhyay","year":"2003","unstructured":"Bandyopadhyay M, Chakrabarti C (2003) Deterministic and stochastic analysis of a nonlinear prey-predator system. J Biol Syst 11(02):161\u2013172. https:\/\/doi.org\/10.1142\/S0218339003000816","journal-title":"J Biol Syst"},{"issue":"2","key":"9501_CR4","doi-asserted-by":"publisher","first-page":"319","DOI":"10.3390\/v13020319","volume":"13","author":"E Bazarragchaa","year":"2021","unstructured":"Bazarragchaa E, Isoda N, Kim T, Tetsuo M, Ito S, Matsuno K, Sakoda Y (2021) Efficacy of oral vaccine against classical swine fever in wild boar and estimation of the disease dynamics in the quantitative approach. Viruses 13(2):319. https:\/\/doi.org\/10.3390\/v13020319","journal-title":"Viruses"},{"issue":"3","key":"9501_CR5","doi-asserted-by":"publisher","first-page":"1186","DOI":"10.1016\/j.gr.2013.12.008","volume":"25","author":"KH Black","year":"2014","unstructured":"Black KH, Price GJ, Archer M, Hand SJ (2014) Bearing up well? understanding the past, present and future of australia\u2019s koalas. Gondwana Res 25(3):1186\u20131201. https:\/\/doi.org\/10.1016\/j.gr.2013.12.008","journal-title":"Gondwana Res"},{"key":"9501_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.idm.2019.12.002","volume":"5","author":"M-G Cojocaru","year":"2020","unstructured":"Cojocaru M-G, Migot T, Jaber A (2020) Controlling infection in predator-prey systems with transmission dynamics. Infectious Disease Modelling 5:1\u201311. https:\/\/doi.org\/10.1016\/j.idm.2019.12.002","journal-title":"Infectious Disease Modelling"},{"issue":"02","key":"9501_CR7","doi-asserted-by":"publisher","first-page":"1550015","DOI":"10.1142\/S1793524515500151","volume":"8","author":"KP Das","year":"2015","unstructured":"Das KP, Chattopadhyay J (2015) A mathematical study of a predator-prey model with disease circulating in the both populations. Int J Biomath 8(02):1550015. https:\/\/doi.org\/10.1142\/S1793524515500151","journal-title":"Int J Biomath"},{"key":"9501_CR8","doi-asserted-by":"publisher","unstructured":"Diekmann O, Heesterbeek JAP, Metz JA (1990) On the definition and the computation of the basic reproduction ratio [CDATA[R_0]]$$R_0$$ in models for infectious diseases in heterogeneous populations. J Math Biol 28(4):365\u2013382. https:\/\/doi.org\/10.1007\/BF00178324","DOI":"10.1007\/BF00178324"},{"issue":"1","key":"9501_CR9","doi-asserted-by":"publisher","first-page":"2332279","DOI":"10.1080\/17513758.2024.2332279","volume":"18","author":"Y Enatsu","year":"2024","unstructured":"Enatsu Y, Roy J, Banerjee M (2024) Hunting cooperation in a prey-predator model with maturation delay. J Biol Dyn 18(1):2332279. https:\/\/doi.org\/10.1080\/17513758.2024.2332279","journal-title":"J Biol Dyn"},{"key":"9501_CR10","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.ecocom.2013.02.005","volume":"14","author":"A Erbach","year":"2013","unstructured":"Erbach A, Lutscher F, Seo G (2013) Bistability and limit cycles in generalist predator-prey dynamics. Ecol Complex 14:48\u201355. https:\/\/doi.org\/10.1016\/j.ecocom.2013.02.005","journal-title":"Ecol Complex"},{"issue":"1","key":"9501_CR11","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-019-42702-z","volume":"9","author":"J Fabijan","year":"2019","unstructured":"Fabijan J, Caraguel C, Jelocnik M, Polkinghorne A, Boardman WS, Nishimoto E, Johnsson G, Molsher R, Woolford L, Timms P et al (2019) Chlamydia pecorum prevalence in south australian koala (phascolarctos cinereus) populations: Identification and modelling of a population free from infection. Sci Rep 9(1):1\u201311. https:\/\/doi.org\/10.1038\/s41598-019-42702-z","journal-title":"Sci Rep"},{"issue":"3\u20134","key":"9501_CR12","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1016\/j.vetmic.2011.11.005","volume":"156","author":"D Higgins","year":"2012","unstructured":"Higgins D, Beninati T, Meek M, Irish J, Griffith J (2012) Within-population diversity of koala chlamydophila pecorum at ompa vd1-vd3 and the orf663 hypothetical gene. Vet Microbiol 156(3\u20134):353\u2013358. https:\/\/doi.org\/10.1016\/j.vetmic.2011.11.005","journal-title":"Vet Microbiol"},{"issue":"3","key":"9501_CR13","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1137\/S0036144500378302","volume":"43","author":"DJ Higham","year":"2001","unstructured":"Higham DJ (2001) An algorithmic introduction to numerical simulation of stochastic differential equations. SIAM Rev 43(3):525\u2013546. https:\/\/doi.org\/10.1137\/S0036144500378302","journal-title":"SIAM Rev"},{"issue":"7","key":"9501_CR14","doi-asserted-by":"publisher","first-page":"385","DOI":"10.4039\/Ent91385-7","volume":"91","author":"CS Holling","year":"1959","unstructured":"Holling CS (1959) Some characteristics of simple types of predation and parasitism. Can Entomol 91(7):385\u2013398. https:\/\/doi.org\/10.4039\/Ent91385-7","journal-title":"Can Entomol"},{"issue":"4","key":"9501_CR15","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1046\/j.1442-9993.2003.01300.x","volume":"28","author":"L Hughes","year":"2003","unstructured":"Hughes L (2003) Climate change and australia: Trends, projections and impacts. Austral Ecol 28(4):423\u2013443. https:\/\/doi.org\/10.1046\/j.1442-9993.2003.01300.x","journal-title":"Austral Ecol"},{"key":"9501_CR16","volume-title":"Biology of the koala","author":"AK Lee","year":"1991","unstructured":"Lee AK, Handasyde KA, Sanson GD (1991) Biology of the koala. Surrey Beatty & Sons, In Biology of the koala"},{"key":"9501_CR17","doi-asserted-by":"publisher","unstructured":"Lunney, D., Crowther, M.S., Wallis, I., Foley, W.J., Lemon, J., Wheeler, R., Madani, G., Orscheg, C., Griffith, J.E., Krockenberger, M., et al. (2012). Koalas and climate change: A case study on the liverpool plains, north-west new south wales. Wildlife and Climate Change: towards robust conservation strategies for Australian Fauna\u2019.(Eds D. Lunney and P. Hutchings.) pp, 150\u2013168. https:\/\/doi.org\/10.7882\/FS.2012.022","DOI":"10.7882\/FS.2012.022"},{"key":"9501_CR18","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1051\/mmnp\/2022007","volume":"17","author":"K Manna","year":"2022","unstructured":"Manna K, Banerjee M (2022) Spatiotemporal pattern formation in a prey-predator model with generalist predator. Mathematical Modelling of Natural Phenomena 17:6. https:\/\/doi.org\/10.1051\/mmnp\/2022007","journal-title":"Mathematical Modelling of Natural Phenomena"},{"key":"9501_CR19","doi-asserted-by":"publisher","DOI":"10.1142\/p473","author":"X Mao","year":"2006","unstructured":"Mao X, Yuan C (2006) Stochastic differential equations with markovian switching. Imperial college press. https:\/\/doi.org\/10.1142\/p473","journal-title":"Imperial college press"},{"issue":"1","key":"9501_CR20","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1016\/j.jtbi.2008.04.011","volume":"254","author":"S Marino","year":"2008","unstructured":"Marino S, Hogue IB, Ray CJ, Kirschner DE (2008) A methodology for performing global uncertainty and sensitivity analysis in systems biology. J Theor Biol 254(1):178\u2013196. https:\/\/doi.org\/10.1016\/j.jtbi.2008.04.011","journal-title":"J Theor Biol"},{"key":"9501_CR21","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1016\/j.biocon.2015.09.020","volume":"192","author":"C McAlpine","year":"2015","unstructured":"McAlpine C, Lunney D, Melzer A, Menkhorst P, Phillips S, Phalen D, Ellis W, Foley W, Baxter G, De Villiers D et al (2015) Conserving koalas: A review of the contrasting regional trends, outlooks and policy challenges. Biol Cons 192:226\u2013236. https:\/\/doi.org\/10.1016\/j.biocon.2015.09.020","journal-title":"Biol Cons"},{"key":"9501_CR22","doi-asserted-by":"publisher","DOI":"10.1016\/j.sciaf.2023.e01837","volume":"21","author":"M Mukherjee","year":"2023","unstructured":"Mukherjee M, Pal D, Mahato S, Bonyah E (2023) Prey-predator optimal harvesting mathematical model in the presence of toxic prey under interval uncertainty. Scientific African 21:e01837. https:\/\/doi.org\/10.1016\/j.sciaf.2023.e01837","journal-title":"Scientific African"},{"key":"9501_CR23","doi-asserted-by":"publisher","unstructured":"Nandi SK, Mondal PK, Jana S, Haldar P, Kar T (2015) Prey-predator model with two-stage infection in prey: Concerning pest control. Journal of Nonlinear Dynamics 2015. https:\/\/doi.org\/10.1155\/2015\/948728","DOI":"10.1155\/2015\/948728"},{"issue":"1","key":"9501_CR24","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0025-5564(01)00087-6","volume":"175","author":"MG Neubert","year":"2002","unstructured":"Neubert MG, Caswell H, Murray J (2002) Transient dynamics and pattern formation: Reactivity is necessary for turing instabilities. Math Biosci 175(1):1\u201311. https:\/\/doi.org\/10.1016\/S0025-5564(01)00087-6","journal-title":"Math Biosci"},{"issue":"1","key":"9501_CR25","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0210245","volume":"14","author":"S Nyari","year":"2019","unstructured":"Nyari S, Booth R, Quigley BL, Waugh CA, Timms P (2019) Therapeutic effect of a chlamydia pecorum recombinant major outer membrane protein vaccine on ocular disease in koalas (phascolarctos cinereus). PLoS ONE 14(1):e0210245. https:\/\/doi.org\/10.1371\/journal.pone.0210245","journal-title":"PLoS ONE"},{"issue":"5","key":"9501_CR26","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0097031","volume":"9","author":"MV Palmer","year":"2014","unstructured":"Palmer MV, Thacker TC, Waters WR, Robbe-Austerman S (2014) Oral vaccination of white-tailed deer (odocoileus virginianus) with mycobacterium bovis bacillus calmette-guerin (bcg). PLoS ONE 9(5):e97031. https:\/\/doi.org\/10.1371\/journal.pone.0097031","journal-title":"PLoS ONE"},{"issue":"2","key":"9501_CR27","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1177\/0300985818806963","volume":"56","author":"C Palmieri","year":"2019","unstructured":"Palmieri C, Hulse L, Pagliarani S, Larkin R, Higgins DP, Beagley K, Johnston S (2019) Chlamydia pecorum infection in the male reproductive system of koalas (phascolarctos cinereus). Vet Pathol 56(2):300\u2013306. https:\/\/doi.org\/10.1177\/0300985818806963","journal-title":"Vet Pathol"},{"issue":"7","key":"9501_CR28","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1071\/WR16163","volume":"44","author":"HJ Reckless","year":"2018","unstructured":"Reckless HJ, Murray M, Crowther MS (2018) A review of climatic change as a determinant of the viability of koala populations. Wildl Res 44(7):458\u2013470. https:\/\/doi.org\/10.1071\/WR16163","journal-title":"Wildl Res"},{"issue":"2","key":"9501_CR29","doi-asserted-by":"publisher","first-page":"225","DOI":"10.7589\/0090-3558-26.2.225","volume":"26","author":"RC Rosatte","year":"1990","unstructured":"Rosatte RC, Howard DR, Campbell JB, Maclnnes CD (1990) Intramuscular vaccination of skunks and raccoons against rabies. J Wildl Dis 26(2):225\u2013230. https:\/\/doi.org\/10.7589\/0090-3558-26.2.225","journal-title":"J Wildl Dis"},{"key":"9501_CR30","doi-asserted-by":"publisher","DOI":"10.1016\/j.aml.2023.108659","volume":"142","author":"J Roy","year":"2023","unstructured":"Roy J, Banerjee M (2023) Global stability of a predator-prey model with generalist predator. Appl Math Lett 142:108659. https:\/\/doi.org\/10.1016\/j.aml.2023.108659","journal-title":"Appl Math Lett"},{"key":"9501_CR31","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1016\/j.matcom.2023.04.019","volume":"211","author":"J Roy","year":"2023","unstructured":"Roy J, Dey S, Banerjee M (2023) Maturation delay induced stability enhancement and shift of bifurcation thresholds in a predator-prey model with generalist predator. Math Comput Simul 211:368\u2013393. https:\/\/doi.org\/10.1016\/j.matcom.2023.04.019","journal-title":"Math Comput Simul"},{"issue":"2","key":"9501_CR32","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1007\/s00285-024-02121-9","volume":"89","author":"J Roy","year":"2024","unstructured":"Roy J, Dey S, Kooi BW, Banerjee M (2024) Prey group defense and hunting cooperation among generalist-predators induce complex dynamics: A mathematical study. J Math Biol 89(2):22. https:\/\/doi.org\/10.1007\/s00285-024-02121-9","journal-title":"J Math Biol"},{"key":"9501_CR33","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecocom.2020.100811","volume":"41","author":"P Roy","year":"2020","unstructured":"Roy P, Jain S, Maama M (2020) Assessing the viability of tri-trophic food chain model in designing a conservation plan: The case of dwindling quokka population. Ecol Complex 41:100811. https:\/\/doi.org\/10.1016\/j.ecocom.2020.100811","journal-title":"Ecol Complex"},{"key":"9501_CR34","doi-asserted-by":"publisher","DOI":"10.1016\/j.eti.2023.103331","volume":"32","author":"F Shabani","year":"2023","unstructured":"Shabani F, Shafapourtehrany M, Ahmadi M, Kalantar B, \u00d6zener H, Clancy K, Esmaeili A, da Silva RS, Beaumont LJ, Llewelyn J et al (2023) Habitat in flames: How climate change will affect fire risk across koala forests. Environmental Technology & Innovation 32:103331. https:\/\/doi.org\/10.1016\/j.eti.2023.103331","journal-title":"Environmental Technology & Innovation"},{"issue":"1","key":"9501_CR35","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0146934","volume":"11","author":"C Waugh","year":"2016","unstructured":"Waugh C, Khan SA, Carver S, Hanger J, Loader J, Polkinghorne A, Beagley K, Timms P (2016) A prototype recombinant-protein based chlamydia pecorum vaccine results in reduced chlamydial burden and less clinical disease in free-ranging koalas (phascolarctos cinereus). PLoS ONE 11(1):e0146934. https:\/\/doi.org\/10.1371\/journal.pone.0146934","journal-title":"PLoS ONE"},{"issue":"4","key":"9501_CR36","doi-asserted-by":"publisher","first-page":"518","DOI":"10.7882\/AZ.2017.007","volume":"38","author":"F Wedrowicz","year":"2017","unstructured":"Wedrowicz F, Wright W, Schlagloth R, Santamaria F, Cahir F (2017) Landscape, koalas and people: A historical account of koala populations and their environment in south gippsland. Australian Zoologist 38(4):518\u2013536. https:\/\/doi.org\/10.7882\/AZ.2017.007","journal-title":"Australian Zoologist"},{"issue":"5","key":"9501_CR37","doi-asserted-by":"publisher","DOI":"10.1111\/csp2.188","volume":"2","author":"DA Whisson","year":"2020","unstructured":"Whisson DA, Ashman KR (2020) When an iconic native animal is overabundant: The koala in southern australia. Conservation Science and Practice 2(5):e188. https:\/\/doi.org\/10.1111\/csp2.188","journal-title":"Conservation Science and Practice"},{"key":"9501_CR38","doi-asserted-by":"publisher","DOI":"10.1016\/j.nonrwa.2023.104018","volume":"76","author":"H Xu","year":"2024","unstructured":"Xu H, Zou S (2024) A diffusive monod-haldane predator-prey system with smith growth and a protection zone. Nonlinear Anal Real World Appl 76:104018. https:\/\/doi.org\/10.1016\/j.nonrwa.2023.104018","journal-title":"Nonlinear Anal Real World Appl"}],"container-title":["Acta Biotheoretica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10441-025-09501-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10441-025-09501-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10441-025-09501-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T09:43:50Z","timestamp":1757411030000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10441-025-09501-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,12]]},"references-count":38,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["9501"],"URL":"https:\/\/doi.org\/10.1007\/s10441-025-09501-8","relation":{},"ISSN":["0001-5342","1572-8358"],"issn-type":[{"type":"print","value":"0001-5342"},{"type":"electronic","value":"1572-8358"}],"subject":[],"published":{"date-parts":[[2025,8,12]]},"assertion":[{"value":"25 April 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 July 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 August 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors affirm that they have no known financial or interpersonal conflicts that would have appeared to impact the research presented in this study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of Interest"}}],"article-number":"12"}}