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We found that (1) the initiation of drug use was associated with a 7.2% (Ratio=1.072, 95% CI 1.006 - 1.142, p\u2009=\u20090.03) increase in family support among LSMM who reported high depressive symptoms (depression subscale T-score \u2265 63) in at least one data wave; (2) a 1-unit increase in family support was associated with a 4.7% (RR\u2009=\u2009;0.953, 95% CI 0.931 - 0.976, p &lt; 0.001) decrease in the probability of high depressive symptoms; and (3) no significant association between a change in drug use and a change in high depressive symptoms. Over time, LSMM appear to benefit from the health effects of family support associated with Latinx family structures.<\/jats:p>","DOI":"10.1007\/s10461-023-04098-w","type":"journal-article","created":{"date-parts":[[2023,6,12]],"date-time":"2023-06-12T11:02:23Z","timestamp":1686567743000},"page":"3844-3851","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Drug Use, Family Support, and Depressive Symptoms Among Latinx Sexual Minority Men: A Longitudinal Analysis"],"prefix":"10.1007","volume":"27","author":[{"given":"Homero E.","family":"del Pino","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nina T.","family":"Harawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven J.","family":"Shoptaw","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katrina","family":"Schrode","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arun","family":"Karlamangla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,6,12]]},"reference":[{"issue":"6","key":"4098_CR1","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1002\/jcop.20392","volume":"38","author":"C Ayon","year":"2010","unstructured":"Ayon C, Marsiglia FF, Bermudez-Parsai M. 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