{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T23:07:45Z","timestamp":1790636865152,"version":"4.1.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T00:00:00Z","timestamp":1740960000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T00:00:00Z","timestamp":1740960000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100009054","name":"U.S. President\u2019s Emergency Plan for AIDS Relief","doi-asserted-by":"publisher","award":["U2GGH002173"],"award-info":[{"award-number":["U2GGH002173"]}],"id":[{"id":"10.13039\/100009054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001713","name":"European and Developing Countries Clinical Trials Partnership","doi-asserted-by":"publisher","award":["TMA2019SFP-2818"],"award-info":[{"award-number":["TMA2019SFP-2818"]}],"id":[{"id":"10.13039\/501100001713","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Malawi HIV Implementation Research Scientist (MHIRST) Training Program","award":["Malawi HIV Implementation Research Scientist (MHIRST) Training Program"],"award-info":[{"award-number":["Malawi HIV Implementation Research Scientist (MHIRST) Training Program"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["AIDS Behav"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>Young People Living with HIV (YPLHIV, 15\u201324 years) are an important demographic of Persons Living with HIV (PLHIV) globally and in Southern Africa. However, YPLHIV experience poor outcomes across the HIV diagnostic and treatment cascade due to multiple factors. We estimated the prevalence and determinants of HIV viral suppression in YPLHIV on antiretroviral therapy (ART) in selected Southern African countries. We used publicly available data from Malawi, Zimbabwe, Mozambique, Lesotho, and Eswatini collected during the Population-based HIV Impact Assessments (PHIAs) of 2020 to 2021. Weighted proportions, and 95% confidence intervals (CI) were computed to estimate the prevalence of viral suppression (&lt;\u20091000c\/ml) and bivariate and multivariate analyses were conducted to identify determinants of viral suppression. A total of 855 records of YPLHIV on ART were included in the analysis. The prevalence of viral suppression in YPLHIV on ART was 82.4% (95% CI: 76.7, 86.9). Residing in Mozambique and duration on ART were inversely associated with viral suppression; adjusted odds ratios (AORs) of 0.37 (95% CI: 0.14, 0.95), and 0.87 (95% CI: 0.80, 0.94), respectively. A negative result in the depression screen, being married\/cohabitating, and ever switching an ART regimen were positively associated with viral suppression: AORs of 5.78 (95% CI: 2.21, 15.11), 3.72 (95% CI: 1.44, 9.63), and 3.44 (95% CI: 1.69, 7), respectively. YPLHIV had suboptimal viral suppression lower than the UNAIDS 95% targets and may benefit from further research and tailored interventions addressing modifiable factors associated with viral suppression such as depression.<\/jats:p>","DOI":"10.1007\/s10461-025-04662-6","type":"journal-article","created":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T13:28:47Z","timestamp":1741008527000},"page":"1962-1972","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Prevalence and Determinants of Viral Suppression in Young People Living with HIV on Antiretroviral Therapy in Southern Africa: A Cross-Sectional Analysis of HIV Survey Data of 2020 and 2021"],"prefix":"10.1007","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4375-5572","authenticated-orcid":false,"given":"Takondwa Charles","family":"Msosa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alinune","family":"Kabaghe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hussein Hassan","family":"Twabi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Mpinganjira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wongani","family":"Mzumara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion","family":"Sumari-De Boer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rob","family":"Aarnoutse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias Rinke De","family":"Wit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffrey","family":"Chipungu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kennedy","family":"Ngowi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Newton","family":"Kalata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madalo","family":"Mukoka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chisomo","family":"Msefula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iraseni","family":"Swai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boston","family":"Zimba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robina","family":"Semphere","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glory","family":"Makhumba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marriott","family":"Nliwasa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,3,3]]},"reference":[{"key":"4662_CR1","unstructured":"UNAIDS. AIDSinfo. 2022 [cited 2022 Mar 7]. AIDSinfo| UNAIDS. Available from: https:\/\/aidsinfo.unaids.org\/"},{"key":"4662_CR2","unstructured":"UNAIDS, Global. AIDS Strategy 2021\u20132026 \u2014 End Inequalities. End AIDS. [Internet]. [cited 2024 Jul 19]. Available from: https:\/\/www.unaids.org\/sites\/default\/files\/media_asset\/global-AIDS-strategy-2021-2026_en.pdf"},{"issue":"3","key":"4662_CR3","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1093\/clinchem\/hvz010","volume":"66","author":"RR Patel","year":"2020","unstructured":"Patel RR, Curoe KA, Chan PA. Undetectable equals untransmittable: A game changer for HIV prevention. Clin Chem. 2020;66(3):406\u20137.","journal-title":"Clin Chem"},{"issue":"17","key":"4662_CR4","doi-asserted-by":"publisher","first-page":"6163","DOI":"10.3390\/ijerph17176163","volume":"17","author":"NE Thomford","year":"2020","unstructured":"Thomford NE, Mhandire D, Dandara C, Kyei GB. Promoting undetectable equals untransmittable in Sub-Saharan Africa: implication for clinical practice and ART adherence. Int J Environ Res Public Health. 2020;17(17):6163.","journal-title":"Int J Environ Res Public Health"},{"issue":"24","key":"4662_CR5","doi-asserted-by":"publisher","first-page":"2282","DOI":"10.1056\/NEJMoa0907736","volume":"362","author":"RL Shapiro","year":"2010","unstructured":"Shapiro RL, Hughes MD, Ogwu A, Kitch D, Lockman S, Moffat C, et al. Antiretroviral regimens in pregnancy and breast-feeding in Botswana. N Engl J Med. 2010;362(24):2282\u201394.","journal-title":"N Engl J Med"},{"issue":"2S1","key":"4662_CR6","doi-asserted-by":"publisher","first-page":"20027","DOI":"10.7448\/IAS.18.2.20027","volume":"18","author":"LG Bekker","year":"2015","unstructured":"Bekker LG, Johnson L, Wallace M, Hosek S. Building our youth for the future. J Int AIDS Soc. 2015;18(2S1):20027.","journal-title":"J Int AIDS Soc"},{"issue":"2","key":"4662_CR7","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1007\/s10461-018-2255-6","volume":"23","author":"E Umar","year":"2019","unstructured":"Umar E, Levy JA, Bailey RC, Donenberg G, Hershow RC, Mackesy-Amiti ME. Virological Non-suppression and its correlates among adolescents and young people living with HIV in Southern Malawi. AIDS Behav. 2019;23(2):513\u201322.","journal-title":"AIDS Behav"},{"issue":"11","key":"4662_CR8","doi-asserted-by":"publisher","first-page":"e0165936","DOI":"10.1371\/journal.pone.0165936","volume":"11","author":"MK Ramaiya","year":"2016","unstructured":"Ramaiya MK, Sullivan KA, Donnell KO, Cunningham CK, Shayo AM, Mmbaga BT, et al. A qualitative exploration of the mental health and psychosocial contexts of HIV-Positive adolescents in Tanzania. PLoS ONE. 2016;11(11):e0165936.","journal-title":"PLoS ONE"},{"key":"4662_CR9","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.puhe.2017.12.010","volume":"157","author":"N Ammon","year":"2018","unstructured":"Ammon N, Mason S, Corkery JM. Factors impacting antiretroviral therapy adherence among human immunodeficiency virus-positive adolescents in Sub-Saharan Africa: a systematic review. Public Health. 2018;157:20\u201331.","journal-title":"Public Health"},{"issue":"10400","key":"4662_CR10","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1016\/S0140-6736(23)00877-2","volume":"402","author":"LN Broyles","year":"2023","unstructured":"Broyles LN, Luo R, Boeras D, Vojnov L. The risk of sexual transmission of HIV in individuals with low-level HIV viraemia: a systematic review. Lancet. 2023;402(10400):464\u201371.","journal-title":"Lancet"},{"issue":"10189","key":"4662_CR11","doi-asserted-by":"publisher","first-page":"2428","DOI":"10.1016\/S0140-6736(19)30418-0","volume":"393","author":"AJ Rodger","year":"2019","unstructured":"Rodger AJ, Cambiano V, Bruun T, Vernazza P, Collins S, Degen O, et al. Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study. Lancet. 2019;393(10189):2428\u201338.","journal-title":"Lancet"},{"issue":"2","key":"4662_CR12","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1001\/jama.2016.5148","volume":"316","author":"AJ Rodger","year":"2016","unstructured":"Rodger AJ, Cambiano V, Bruun T, Vernazza P, Collins S, van Lunzen J, et al. Sexual activity without condoms and risk of HIV transmission in serodifferent couples when the HIV-Positive partner is using suppressive antiretroviral therapy. JAMA. 2016;316(2):171\u201381.","journal-title":"JAMA"},{"issue":"1","key":"4662_CR13","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1186\/s12879-017-2664-6","volume":"17","author":"N McCreesh","year":"2017","unstructured":"McCreesh N, Andrianakis I, Nsubuga RN, Strong M, Vernon I, McKinley TJ, et al. Improving ART programme retention and viral suppression are key to maximising impact of treatment as prevention\u2013 a modelling study. BMC Infect Dis. 2017;17(1):557.","journal-title":"BMC Infect Dis"},{"issue":"5","key":"4662_CR14","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1136\/jech-2015-205952","volume":"70","author":"D Wight","year":"2016","unstructured":"Wight D, Wimbush E, Jepson R, Doi L. Six steps in quality intervention development (6SQuID). J Epidemiol Community Health. 2016;70(5):520\u20135.","journal-title":"J Epidemiol Community Health"},{"key":"4662_CR15","unstructured":"Ministry of Health (MOH). Malawi. Malawi Population-based HIV Impact Assessment 2020\u20132021 (MPHIA 2020\u20132021): Final Report [Internet]. Lilongwe: MOH, Malawi; 2022 Nov [cited 2023 Jun 20]. Available from: https:\/\/phia.icap.columbia.edu\/wp-content\/uploads\/2022\/12\/241122_Mphia_Foreword.pdf"},{"key":"4662_CR16","unstructured":"Ministry of Health (MOH). Eswatini. Eswatini Population-based HIV Impact Assessment 3 2021 (SHIMS3 2021): Final Report [Internet]. 2023 Nov [cited 2024 Nov 26]. Available from: https:\/\/phia.icap.columbia.edu\/wp-content\/uploads\/2023\/12\/241123_SHIMS_ENG_RR3_Final-1.pdf"},{"key":"4662_CR17","unstructured":"Instituto Nacional de Sa\u00fade (INS). Mozambique Population-based HIV Impact Assessment 2021 (INSIDA 2021) [Internet]. Instituto Nacional de Sa\u00fade (INS); 2023 Jul [cited 2024 Nov 26]. Available from: https:\/\/phia.icap.columbia.edu\/wp-content\/uploads\/2023\/10\/050324_INSIDA_ENG_RR5.pdf"},{"key":"4662_CR18","unstructured":"Lesotho Ministry of Health (MOH). Lesotho Population-based HIV Impact Assessment 2020 (LePHIA 2020) [Internet]. Lesotho Ministry of Health (MOH); 2022 Jun [cited 2024 Nov 26]. Available from: https:\/\/phia.icap.columbia.edu\/wp-content\/uploads\/2021\/11\/260622_LePHIA_RR3_Final_Digital_v2.pdf"},{"key":"4662_CR19","unstructured":"Ministry of Health and Child Care (MoHCC). Zimbabwe Population-based HIV Impact Assessment 2020 (ZIMPHIA 2020) [Internet]. Ministry of Health and Child Care (MoHCC).; 2021 Dec [cited 2024 Nov 26]. Available from: https:\/\/phia.icap.columbia.edu\/wp-content\/uploads\/2023\/09\/010923_ZIMPHIA2020-interactive-versionFinal.pdf"},{"key":"4662_CR20","unstructured":"ICAP at Columbia University. Population-based HIV Impact Assessment (PHIA) Data Use Manual [Internet]. [cited 2024 Mar 11]. Available from: https:\/\/phia-data.icap.columbia.edu\/storage\/Country\/28-09-2021-22-01-17-615390ad6a147.pdf."},{"key":"4662_CR21","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/1751-0473-3-17","volume":"3","author":"Z Bursac","year":"2008","unstructured":"Bursac Z, Gauss CH, Williams DK, Hosmer DW. Purposeful selection of variables in logistic regression. Source Code Biol Med. 2008;3:17.","journal-title":"Source Code Biol Med"},{"issue":"7","key":"4662_CR22","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1097\/QAD.0000000000002538","volume":"34","author":"I Njuguna","year":"2020","unstructured":"Njuguna I, Neary J, Mburu C, Black D, Beima-Sofie K, Wagner AD, et al. Clinic-level and individual-level factors that influence HIV viral suppression in adolescents and young adults: a National survey in Kenya. AIDS. 2020;34(7):1065.","journal-title":"AIDS"},{"issue":"1","key":"4662_CR23","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1186\/s12981-021-00391-7","volume":"18","author":"EF Okonji","year":"2021","unstructured":"Okonji EF, van Wyk B, Mukumbang FC, Hughes GD. Determinants of viral suppression among adolescents on antiretroviral treatment in ehlanzeni district, South Africa: a cross-sectional analysis. AIDS Res Ther. 2021;18(1):66.","journal-title":"AIDS Res Ther"},{"issue":"3","key":"4662_CR24","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1097\/COH.0000000000000459","volume":"13","author":"LA Enane","year":"2018","unstructured":"Enane LA, Vreeman RC, Foster C. Retention and adherence: global challenges for the long-term care of adolescents and young adults living with HIV. Curr Opin HIV AIDS. 2018;13(3):212.","journal-title":"Curr Opin HIV AIDS"},{"issue":"1","key":"4662_CR25","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1097\/JNC.0000000000000302","volume":"33","author":"K Wilson","year":"2022","unstructured":"Wilson K, Onyango A, Mugo C, Guthrie B, Slyker J, Richardson B, et al. Kenyan HIV clinics with Youth-Friendly services and trained providers have a higher prevalence of viral suppression among adolescents and young adults: results from an observational study. J Assoc Nurses AIDS Care JANAC. 2022;33(1):45\u201353.","journal-title":"J Assoc Nurses AIDS Care JANAC"},{"issue":"6","key":"4662_CR26","doi-asserted-by":"publisher","first-page":"1849","DOI":"10.1007\/s10461-022-03916-x","volume":"27","author":"AD Haas","year":"2023","unstructured":"Haas AD, Lienhard R, Didden C, Cornell M, Folb N, Boshomane TMG, et al. Mental health, ART adherence, and viral suppression among adolescents and adults living with HIV in South Africa: A cohort study. AIDS Behav. 2023;27(6):1849\u201361.","journal-title":"AIDS Behav"},{"key":"4662_CR27","unstructured":"The World Health Organisation. Integration of mental health and HIV interventions [Internet]. [cited 2024 Mar 12]. Available from: https:\/\/iris.who.int\/bitstream\/handle\/10665\/353571\/9789240043176-eng.pdf?sequence=1"},{"issue":"Suppl 2","key":"4662_CR28","doi-asserted-by":"publisher","first-page":"e25722","DOI":"10.1002\/jia2.25722","volume":"24","author":"E Nakimuli-Mpungu","year":"2021","unstructured":"Nakimuli-Mpungu E, Musisi S, Smith CM, Von Isenburg M, Akimana B, Shakarishvili A, et al. Mental health interventions for persons living with HIV in low- and middle-income countries: a systematic review. J Int AIDS Soc. 2021;24(Suppl 2):e25722.","journal-title":"J Int AIDS Soc"},{"issue":"Suppl 2","key":"4662_CR29","doi-asserted-by":"publisher","first-page":"e25748","DOI":"10.1002\/jia2.25748","volume":"24","author":"RH Remien","year":"2021","unstructured":"Remien RH, Patel V, Chibanda D, Abas MA. Integrating mental health into HIV prevention and care: a call to action. J Int AIDS Soc. 2021;24(Suppl 2):e25748.","journal-title":"J Int AIDS Soc"},{"issue":"5","key":"4662_CR30","doi-asserted-by":"publisher","first-page":"e104","DOI":"10.1192\/bjo.2020.67","volume":"6","author":"A Bhana","year":"2020","unstructured":"Bhana A, Abas MA, Kelly J, van Pinxteren M, Mudekunye LA, Pantelic M. Mental health interventions for adolescents living with HIV or affected by HIV in low- and middle-income countries: systematic review. BJPsych Open. 2020;6(5):e104.","journal-title":"BJPsych Open"},{"issue":"Suppl 2","key":"4662_CR31","doi-asserted-by":"publisher","first-page":"e25713","DOI":"10.1002\/jia2.25713","volume":"24","author":"A Bhana","year":"2021","unstructured":"Bhana A, Kreniske P, Pather A, Abas MA, Mellins CA. Interventions to address the mental health of adolescents and young adults living with or affected by HIV: state of the evidence. J Int AIDS Soc. 2021;24(Suppl 2):e25713.","journal-title":"J Int AIDS Soc"},{"issue":"6","key":"4662_CR32","doi-asserted-by":"publisher","first-page":"2015","DOI":"10.1007\/s10461-021-03550-z","volume":"26","author":"DE Dow","year":"2022","unstructured":"Dow DE, O\u2019Donnell KE, Mkumba L, Gallis JA, Turner EL, Boshe J, et al. Sauti Ya Vijana (SYV; the voice of Youth): Longitudinal Outcomes of an Individually Randomized Group Treatment Pilot Trial for Young People Living with HIV in Tanzania. AIDS Behav. 2022;26(6):2015\u201325.","journal-title":"AIDS Behav"},{"key":"4662_CR33","doi-asserted-by":"crossref","unstructured":"E NM SM. K W, J O, S N, J B, Effectiveness and cost-effectiveness of group support psychotherapy delivered by trained lay health workers for depression treatment among people with HIV in Uganda: a cluster-randomised trial. Lancet Glob Health [Internet]. 2020 Mar [cited 2024 Oct 10];8(3). Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/32035035\/","DOI":"10.1016\/S2214-109X(19)30548-0"},{"issue":"1","key":"4662_CR34","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1007\/s10461-021-03376-9","volume":"26","author":"A Chory","year":"2022","unstructured":"Chory A, Callen G, Nyandiko W, Njoroge T, Ashimosi C, Aluoch J, et al. A pilot study of a mobile intervention to support mental health and adherence among adolescents living with HIV in Western Kenya. AIDS Behav. 2022;26(1):232\u201342.","journal-title":"AIDS Behav"},{"issue":"1","key":"4662_CR35","doi-asserted-by":"publisher","first-page":"e54635","DOI":"10.2196\/54635","volume":"13","author":"P Nabunya","year":"2024","unstructured":"Nabunya P, Cavazos-Rehg P, Mugisha J, Kasson E, Namuyaba OI, Najjuuko C, et al. An mHealth intervention to address depression and improve antiretroviral therapy adherence among youths living with HIV in Uganda: protocol for a pilot randomized controlled trial. JMIR Res Protoc. 2024;13(1):e54635.","journal-title":"JMIR Res Protoc"},{"issue":"3","key":"4662_CR36","doi-asserted-by":"publisher","first-page":"e2540","DOI":"10.1002\/rmv.2540","volume":"34","author":"IH Mosha","year":"2024","unstructured":"Mosha IH, Nyondo GG, Munishi CG, Njiro BJ, Bwire GM. Prevalence and factors associated with viral non-suppression in people living with HIV receiving antiretroviral therapy in sub-Saharan Africa: A systematic review and meta-analysis. Rev Med Virol. 2024;34(3):e2540.","journal-title":"Rev Med Virol"},{"issue":"1","key":"4662_CR37","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1097\/OLQ.0000000000000376","volume":"43","author":"KG Toren","year":"2016","unstructured":"Toren KG, Buskin SE, Dombrowski JC, Cassels SL, Golden MR. Time from HIV diagnosis to viral load suppression: 2007\u20132013. Sex Transm Dis. 2016;43(1):34.","journal-title":"Sex Transm Dis"},{"key":"4662_CR38","doi-asserted-by":"publisher","first-page":"100238","DOI":"10.1016\/j.eclinm.2019.100238","volume":"18","author":"L Zuo","year":"2020","unstructured":"Zuo L, Liu K, Liu H, Hu Y, Zhang Z, Qin J, et al. Trend of HIV-1 drug resistance in China: A systematic review and meta-analysis of data accumulated over 17 years (2001\u20132017). EClinicalMedicine. 2020;18:100238.","journal-title":"EClinicalMedicine"},{"key":"4662_CR39","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1186\/s12879-019-3871-0","volume":"19","author":"D Takou","year":"2019","unstructured":"Takou D, Fokam J, Teto G, Santoro MM, Ceccherini-Silberstein F, Nanfack AJ, et al. HIV-1 drug resistance testing is essential for heavily-treated patients switching from first- to second-line regimens in resource-limited settings: evidence from routine clinical practice in Cameroon. BMC Infect Dis. 2019;19:246.","journal-title":"BMC Infect Dis"},{"issue":"3","key":"4662_CR40","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1080\/13548506.2014.945601","volume":"20","author":"KR Claborn","year":"2015","unstructured":"Claborn KR, Meier E, Miller MB, Leffingwell TR. A systematic review of treatment fatigue among HIV-infected patients prescribed antiretroviral therapy. Psychol Health Med. 2015;20(3):255\u201365.","journal-title":"Psychol Health Med"},{"issue":"5","key":"4662_CR41","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1097\/QAI.0000000000002075","volume":"81","author":"RM Nance","year":"2019","unstructured":"Nance RM, Vannappagari V, Smith K, Johannes CB, Calingaert B, Saltus CW, et al. Virologic failure among people living with HIV initiating Dolutegravir-Based versus other recommended regimens in Real-World clinical care settings. JAIDS J Acquir Immune Defic Syndr. 2019;81(5):572.","journal-title":"JAIDS J Acquir Immune Defic Syndr"},{"issue":"7","key":"4662_CR42","doi-asserted-by":"publisher","first-page":"1013","DOI":"10.1097\/QAD.0000000000003835","volume":"38","author":"A Devendra","year":"2024","unstructured":"Devendra A, Kohler M, Letsika M, Khooa H, Motaboli L, Lerotholi M, et al. HIV viral suppression in children and adolescents 2 years after transition to dolutegravir: a multicentre cohort study. AIDS. 2024;38(7):1013.","journal-title":"AIDS"}],"container-title":["AIDS and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10461-025-04662-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10461-025-04662-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10461-025-04662-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:24:04Z","timestamp":1747185844000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10461-025-04662-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,3]]},"references-count":42,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["4662"],"URL":"https:\/\/doi.org\/10.1007\/s10461-025-04662-6","relation":{},"ISSN":["1090-7165","1573-3254"],"issn-type":[{"value":"1090-7165","type":"print"},{"value":"1573-3254","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,3]]},"assertion":[{"value":"14 February 2025","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 March 2025","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The PHIA surveys are supported by PEPFAR through the U.S. CDC. The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the funding agencies.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"CDC Disclaimer"}},{"value":"None of the authors have any conflicts of interest to declare.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}