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This qualitative study explored the lived experiences of Dutch young adults (aged 20\u201330) with perinatal HIV, focusing on their transition to adulthood and from pediatric to adult care. Semi-structured interviews were conducted with 11 participants. While the findings are based on a small, self-selected sample and are not intended to be statistically representative, they offer in-depth insight into key challenges during transition. The findings highlight the profound impact of stigma and selective disclosure of HIV-status. Parental support was important but complex, especially when views on disclosure differed. Peer contact could provide a sense of connection, though many did not feel the need for ongoing involvement. Participants described challenges in social and professional contexts. Experiences with the transition to adult care varied, with more recent transfers being more positive. Valued key elements of transitional care included support from nurse specialists, meeting the adult provider beforehand, and a warm welcome in adult care. Despite stable medical management, the psychological burden of stigma and fear of disclosure remained significant. These findings underscore the need for tailored transition programs addressing medical, psychosocial and emotional needs, including psychological support, structured attention to family dynamics, pre-transfer meetings with adult providers, and peer support.<\/jats:p>","DOI":"10.1007\/s10461-026-05047-z","type":"journal-article","created":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T11:33:24Z","timestamp":1770032004000},"page":"2224-2233","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Transition to Adulthood and Adult Care: Lived Experiences of Young Adults with Perinatal HIV in the Netherlands"],"prefix":"10.1007","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0433-5022","authenticated-orcid":false,"given":"Jane N. 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No financial, personal, or professional conflicts of interest influenced the design, execution, analysis, or reporting of this research.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was reviewed by the Medical Ethics Committee of Amsterdam UMC and by local ethics committees of the participating centers. It was determined that the study did not fall under the scope of the Dutch Medical Research Involving Human Subjects Act (WMO).","order":2,"name":"Ethics","label":"Ethical Approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Informed consent was obtained from all participants prior to the interviews. All data were stored and handled in accordance with the General Data Protection Regulation (GDPR).","order":3,"name":"Ethics","label":"Consent to Participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":4,"name":"Ethics","label":"Consent for Publication","group":{"name":"EthicsHeading","label":"Declarations"}}]}}