{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T03:25:39Z","timestamp":1787109939283,"version":"build-2736575974"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:00:00Z","timestamp":1773705600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:00:00Z","timestamp":1773705600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["R21 DA056835"],"award-info":[{"award-number":["R21 DA056835"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["AIDS Behav"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    This study examined PrEP awareness among HIV-negative individuals in treatment for opioid use disorder (OUD;\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u2009179), and associations with demographic characteristics, sexual and injection behaviors, and treatment modalities. Overall, 48% of participants reported PrEP awareness. Bivariate logistic regression showed that, compared to others, individuals who were older, African American\/Black, and in methadone treatment less frequently reported PrEP awareness (\n                    <jats:italic>p<\/jats:italic>\n                    \u2264.018), while those who reported sex with a person who injects drugs, inpatient\/day treatment, and self-help group attendance more frequently reported PrEP awareness (\n                    <jats:italic>p<\/jats:italic>\n                    \u2264.041). Increased education and outreach to PrEP eligible individuals in methadone and other opioid treatment programs appears warranted.\n                  <\/jats:p>","DOI":"10.1007\/s10461-026-05057-x","type":"journal-article","created":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T06:04:42Z","timestamp":1773727482000},"page":"2328-2332","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["HIV Pre-Exposure Prophylaxis Awareness among Individuals in Treatment for Opioid Use Disorder in the United States: A Cross-Sectional Study"],"prefix":"10.1007","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5001-7391","authenticated-orcid":false,"given":"Mance E.","family":"Buttram","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew S.","family":"Ellis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 F. Col\u00f3n","family":"Burgos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,17]]},"reference":[{"key":"5057_CR1","doi-asserted-by":"crossref","unstructured":"Chou R, Evans C, Hoverman A, Sun C, Dana T, Bougatsos C, Grusing S, Korthuis PT. (2019). Preexposure prophylaxis for the prevention of HIV infection: evidence report and systematic review for the US Preventive Services Task Force. JAMA. 2019;321(22):2214\u20132230.","DOI":"10.1001\/jama.2019.2591"},{"key":"5057_CR2","unstructured":"Fanfair RN, Mermin J. Expanding PrEP coverage in the United States to achieve the EHE goals. National Center for HIV, Viral Hepatitis, STD, and Tuberculosis Prevention, Centers for Disease Control and Prevention; 2023. Available at https:\/\/www.cdc.gov\/nchhstp\/director-letters\/expanding-prep-coverage.html. Accessed May 6, 2025."},{"key":"5057_CR3","unstructured":"Chapin-Bardales D, Broz D, Eustaquio P et al. Changes in HIV PrEP awareness and use among PWID in 19 US Cities, 2018 and 2022. Conference on Retroviruses and Opportunistic Infections (CROI); 2024; Denver, Colorado, United States."},{"key":"5057_CR4","doi-asserted-by":"publisher","first-page":"1459","DOI":"10.15585\/mmwr.mm7042a1","volume":"70","author":"S Handanagic","year":"2021","unstructured":"Handanagic S, Finlayson T, Burnett JC, Broz D, Wejnert C. HIV infection and HIV-associated behaviors among persons who inject drugs \u2014 23 metropolitan statistical areas, united States, 2018. MMWR Morb Mortal Wkly Rep. 2021;70:1459\u201365.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"5S","key":"5057_CR5","doi-asserted-by":"publisher","first-page":"e170","DOI":"10.1097\/QAI.0000000000003626","volume":"98","author":"K McCoy","year":"2025","unstructured":"McCoy K, Mantell JE, Deiss R, Liu A, Bauman LJ, Bonner CP, Vinson J, Buchbinder S. Pre-exposure prophylaxis awareness and demand creation: overlooked populations and opportunities to move forward. J Acquir Immune Defic Syndr. 2025;98(5S):e170\u201380.","journal-title":"J Acquir Immune Defic Syndr"},{"key":"5057_CR6","volume-title":"Global appraisal of individual needs: GAIN-I and GAIN-M90 walkthrough version 5.7","author":"GAIN Coordinating Center","year":"2016","unstructured":"GAIN Coordinating Center. Global appraisal of individual needs: GAIN-I and GAIN-M90 walkthrough version 5.7. Normal, IL: Chestnut Health Systems; 2016."},{"issue":"1","key":"5057_CR7","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1186\/s13722-024-00478-2","volume":"19","author":"JL Merle","year":"2024","unstructured":"Merle JL, Zapata JP, Quieroz A, Zamantakis A, Sanuade O, Mustanski B, Smith JD. Pre-exposure prophylaxis (PrEP) among people who use drugs: a qualitative scoping review of implementation determinants and change methods. Addict Sci Clin Pract. 2024;19(1):46.","journal-title":"Addict Sci Clin Pract"},{"key":"5057_CR8","doi-asserted-by":"publisher","first-page":"108477","DOI":"10.1016\/j.drugalcdep.2020.108477","volume":"219","author":"Z Ni","year":"2021","unstructured":"Ni Z, Altice FL, Wickersham JA, Copenhaver MM, DiDomizio EE, Nelson LE, Shrestha R. Willingness to initiate pre-exposure prophylaxis (PrEP) and its use among opioid-dependent individuals in drug treatment. Drug Alcohol Depend. 2021;219:108477.","journal-title":"Drug Alcohol Depend"},{"issue":"3","key":"5057_CR9","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1097\/QAI.0000000000000165","volume":"66","author":"GE Woody","year":"2014","unstructured":"Woody GE, Bruce D, Korthuis PT, Chhatre S, Poole S, Hillhouse M, Jacobs P, Sorensen J, Saxon AJ, Metzger D, Ling W. HIV risk reduction with buprenorphine\u2013naloxone or methadone: findings from a randomized trial. J Acquir Immune Defic Syndr. 2014;66(3):288\u201393.","journal-title":"J Acquir Immune Defic Syndr"},{"issue":"1","key":"5057_CR10","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1521\/aeap.2024.36.1.60","volume":"36","author":"K Chan","year":"2024","unstructured":"Chan K, Mitchell MM, Casselle E, Bender AA. Facilitators and barriers to PrEP acceptability and initiation among opioid treatment program patients and staff. AIDS Educ Prev. 2024;36(1):60\u201372.","journal-title":"AIDS Educ Prev"},{"key":"5057_CR11","unstructured":"Federal Opioid Use. Disorder treatment standards\u2009\u2013\u200942 CFR \u00a7 8.12. Available at https:\/\/www.law.cornell.edu\/cfr\/text\/42\/8.12#:~:text=(i)%20Each%20patient%20admitted%20to,services%20are%20to%20be%20provided. Accessed 24 June 2025."},{"key":"5057_CR12","doi-asserted-by":"publisher","first-page":"107616","DOI":"10.1016\/j.drugalcdep.2019.107616","volume":"205","author":"CM Jones","year":"2019","unstructured":"Jones CM, Byrd DJ, Clarke TJ, Campbell TB, Ohuoha C, McCance-Katz EF. Characteristics and current clinical practices of opioid treatment programs in the united States. Drug Alcohol Depend. 2019;205:107616.","journal-title":"Drug Alcohol Depend"}],"container-title":["AIDS and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10461-026-05057-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10461-026-05057-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10461-026-05057-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T02:39:22Z","timestamp":1787107162000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10461-026-05057-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,17]]},"references-count":12,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["5057"],"URL":"https:\/\/doi.org\/10.1007\/s10461-026-05057-x","relation":{},"ISSN":["1090-7165","1573-3254"],"issn-type":[{"value":"1090-7165","type":"print"},{"value":"1573-3254","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,17]]},"assertion":[{"value":"24 January 2026","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 March 2026","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors have no conflicts to declare.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the Institutional Review Boards at the University of Arkansas and Washington University in St. Louis. All procedures were performed in accordance with the Helsinki Declaration.","order":2,"name":"Ethics","label":"Ethical Approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All participants provided informed consent.","order":3,"name":"Ethics","label":"Consent To Participate","group":{"name":"EthicsHeading","label":"Declarations"}}]}}