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The aim of this study was to perform an identification of bacteria responsible for septicemia in three individuals. For all of them, necropsies were made, bacteria classification was performed by traditional and DNA-based molecular methods and tissues were histologically examined. All animals showed edema and ascites, and other tissues such as the lungs, spleen, liver, and kidney were also affected, dermatitis also occurred, in one case, the dermatitis was severe. Two bacterial isolates showed genetic identities of 99% with <jats:italic>Aeromonas veronii<\/jats:italic>, one with <jats:italic>Citrobacter freundii<\/jats:italic>, and another with 100% identity with <jats:italic>Citrobacter portucalensis<\/jats:italic>. These and other Enterobacteriaceae species of <jats:italic>Aeromonas<\/jats:italic> genus have been reported to produce septicemia in Anura amphibians and fish, pointing out that they are a health hazard for aquatic animals. Future endeavors to determine these bacteria prevalence, the search for antibiotic resistance\/susceptibility, factors that can trigger the pathology, and the development of early diagnostic tools should be done to improve our understanding.<\/jats:p>","DOI":"10.1007\/s10482-025-02067-y","type":"journal-article","created":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T11:54:42Z","timestamp":1740830082000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Identification of enterobacteriaceae causing septicemia in the axolotl Ambystoma mexicanum"],"prefix":"10.1007","volume":"118","author":[{"given":"Osvaldo Lopez","family":"Diaz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Buendia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joaqu\u00edn","family":"S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guiehdani","family":"Villalobos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nora","family":"Rojas-Serrania","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Antonio Ocampo","family":"Cervantes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Uranga-Mu\u00f1oz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Martinez-Hernandez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6264-3907","authenticated-orcid":false,"given":"Emilio","family":"Rend\u00f3n-Franco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6679-016X","authenticated-orcid":false,"given":"Claudia Irais","family":"Mu\u00f1oz-Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,3,1]]},"reference":[{"key":"2067_CR1","doi-asserted-by":"publisher","first-page":"6907","DOI":"10.3390\/app13126907","volume":"13","author":"ADJ Cort\u00e9s-S\u00e1nchez","year":"2023","unstructured":"Cort\u00e9s-S\u00e1nchez ADJ, Salgado-Cruz MDLP, Diaz-Ram\u00edrez M, Torres-Ochoa E, Espinosa-Chaurand LD (2023) A review on food safety: the case of Citrobacter sp. 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