{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T22:18:00Z","timestamp":1768256280351,"version":"3.49.0"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T00:00:00Z","timestamp":1765411200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T00:00:00Z","timestamp":1765411200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["12372321"],"award-info":[{"award-number":["12372321"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Antonie van Leeuwenhoek"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1007\/s10482-025-02222-5","type":"journal-article","created":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T07:09:34Z","timestamp":1765436974000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Oscillatory expansion of Bacillus subtilis biofilms on MSgg agar medium"],"prefix":"10.1007","volume":"119","author":[{"given":"Jiahao","family":"Cui","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiecheng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaolei","family":"Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cong","family":"Tao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoling","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,12,11]]},"reference":[{"issue":"16","key":"2222_CR1","doi-asserted-by":"publisher","first-page":"4288","DOI":"10.1073\/pnas.1706920115","volume":"115","author":"F Bocci","year":"2018","unstructured":"Bocci F, Suzuki Y, Lu M, Onuchic JN (2018) Role of metabolic spatiotemporal dynamics in regulating biofilm colony expansion. Proc Natl Acad Sci USA 115(16):4288\u20134293. https:\/\/doi.org\/10.1073\/pnas.1706920115","journal-title":"Proc Natl Acad Sci USA"},{"issue":"5","key":"2222_CR2","doi-asserted-by":"publisher","first-page":"822","DOI":"10.1111\/1758-2229.13099","volume":"14","author":"F Dong","year":"2022","unstructured":"Dong F, Liu S, Zhang D, Zhang J, Wang X (2022) Matrix-producing cells formed \u201cVan Gogh bundles\u201d facilitate Bacillus subtilis biofilm self-healing. Environ Microbiol Rep 14(5):822\u2013827. https:\/\/doi.org\/10.1111\/1758-2229.13099","journal-title":"Environ Microbiol Rep"},{"issue":"11","key":"2222_CR3","doi-asserted-by":"publisher","first-page":"4345","DOI":"10.1073\/pnas.1300321110","volume":"110","author":"K Drescher","year":"2013","unstructured":"Drescher K, Shen Y, Bassler BL, Stone HA (2013) Biofilm streamers cause catastrophic disruption of flow with consequences for environmental and medical systems. Proc Natl Acad Sci USA 110(11):4345\u20134350. https:\/\/doi.org\/10.1073\/pnas.1300321110","journal-title":"Proc Natl Acad Sci USA"},{"issue":"5","key":"2222_CR4","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1007\/s11538-021-00887-3","volume":"83","author":"N Ford","year":"2021","unstructured":"Ford N, Fisher G, Prindle A, Chopp D (2021) A two-dimensional model of potassium signaling and oscillatory growth in a biofilm. Bull Math Biol 83(5):60. https:\/\/doi.org\/10.1007\/s11538-021-00887-3","journal-title":"Bull Math Biol"},{"issue":"1","key":"2222_CR5","doi-asserted-by":"publisher","first-page":"5579","DOI":"10.1038\/s41598-020-62526-6","volume":"10","author":"R Garde","year":"2020","unstructured":"Garde R, Ibrahim B, Schuster S (2020) Extending the minimal model of metabolic oscillations in Bacillus subtilis biofilms. Sci Rep 10(1):5579. https:\/\/doi.org\/10.1038\/s41598-020-62526-6","journal-title":"Sci Rep"},{"issue":"2","key":"2222_CR6","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1038\/nrmicro821","volume":"2","author":"L Hall-Stoodley","year":"2004","unstructured":"Hall-Stoodley L, Costerton JW, Stoodley P (2004) Bacterial biofilms: from the natural environment to infectious diseases. Nat Rev Microbiol 2(2):95\u2013108. https:\/\/doi.org\/10.1038\/nrmicro821","journal-title":"Nat Rev Microbiol"},{"issue":"7562","key":"2222_CR7","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1038\/nature14660","volume":"523","author":"J Liu","year":"2015","unstructured":"Liu J, Prindle A, Humphries J, Gabalda-Sagarra M, Asally M, Lee DYD, Ly S, Garcia-Ojalvo J, Sueel GM (2015) Metabolic co-dependence gives rise to collective oscillations within biofilms. Nature 523(7562):550. https:\/\/doi.org\/10.1038\/nature14660","journal-title":"Nature"},{"issue":"6338","key":"2222_CR8","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1126\/science.aah4204","volume":"356","author":"J Liu","year":"2017","unstructured":"Liu J, Martinez-Corral R, Prindle A, Lee DYD, Larkin J, Gabalda-Sagarra M, Garcia-Ojalvo J, Sueel GM (2017) Coupling between distant biofilms and emergence of nutrient time-sharing. Science 356(6338):638\u2013641. https:\/\/doi.org\/10.1126\/science.aah4204","journal-title":"Science"},{"issue":"25","key":"2222_CR9","doi-asserted-by":"publisher","first-page":"12228","DOI":"10.1073\/pnas.91.25.12228","volume":"91","author":"R Lopez-Franco","year":"1994","unstructured":"Lopez-Franco R, Bartnicki-Garcia S, Bracker CE (1994) Pulsed growth of fungal hyphal tips. Proc Natl Acad Sci USA 91(25):12228\u201312232. https:\/\/doi.org\/10.1073\/pnas.91.25.12228","journal-title":"Proc Natl Acad Sci USA"},{"issue":"36","key":"2222_CR10","doi-asserted-by":"publisher","first-page":"E8333","DOI":"10.1073\/pnas.1805004115","volume":"115","author":"R Martinez-Corral","year":"2018","unstructured":"Martinez-Corral R, Liu J, Sueel GM, Garcia-Ojalvo J (2018) Bistable emergence of oscillations in growing Bacillus subtilis biofilms. Proc Natl Acad Sci USA 115(36):E8333\u2013E8340. https:\/\/doi.org\/10.1073\/pnas.1805004115","journal-title":"Proc Natl Acad Sci USA"},{"key":"2222_CR11","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.neulet.2014.03.041","volume":"570","author":"VI Mironov","year":"2014","unstructured":"Mironov VI, Romanov AS, Simonov AY, Vedunova MV, Kazantsev VB (2014) Oscillations in a neurite growth model with extracellular feedback. Neurosci Lett 570:16\u201320. https:\/\/doi.org\/10.1016\/j.neulet.2014.03.041","journal-title":"Neurosci Lett"},{"issue":"13","key":"2222_CR12","doi-asserted-by":"publisher","first-page":"2707","DOI":"10.1242\/jcs.00468","volume":"116","author":"RM Parton","year":"2003","unstructured":"Parton RM, Fischer-Parton S, Trewavas AJ, Watahiki MK (2003) Pollen tubes exhibit regular periodic membrane trafficking events in the absence of apical extension. J Cell Sci 116(13):2707\u20132719. https:\/\/doi.org\/10.1242\/jcs.00468","journal-title":"J Cell Sci"},{"issue":"2","key":"2222_CR13","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1111\/j.1438-8677.1995.tb00774.x","volume":"44","author":"ES Pierson","year":"1995","unstructured":"Pierson ES, Li YQ, Zhang HQ, Willemse MTM, Linskens HF, Cresti M (1995) Pulsatory growth of pollen tubes: investigation of a possible relationship with the periodic distribution of cell wall components. Acta Bot Neerl 44(2):121\u2013128. https:\/\/doi.org\/10.1111\/j.1438-8677.1995.tb00774.x","journal-title":"Acta Bot Neerl"},{"key":"2222_CR14","doi-asserted-by":"publisher","first-page":"12135","DOI":"10.1038\/s41598-018-30635-y","volume":"8","author":"M Van Hemelryck","year":"2018","unstructured":"Van Hemelryck M, Bernal R, Ispolatov Y, Dumais J (2018) Lily pollen tubes pulse according to a simple spatial oscillator. Sci Rep 8:12135. https:\/\/doi.org\/10.1038\/s41598-018-30635-y","journal-title":"Sci Rep"},{"issue":"9","key":"2222_CR15","doi-asserted-by":"publisher","first-page":"5635","DOI":"10.1007\/s00203-021-02542-w","volume":"203","author":"X Wang","year":"2021","unstructured":"Wang X, Dong F, Liu J, Tan Y, Hu S, Zhao H (2021) The self-healing of Bacillus subtilis biofilms. Arch Microbiol 203(9):5635\u20135645. https:\/\/doi.org\/10.1007\/s00203-021-02542-w","journal-title":"Arch Microbiol"},{"issue":"3","key":"2222_CR16","doi-asserted-by":"publisher","first-page":"848","DOI":"10.1073\/pnas.1216376110","volume":"110","author":"JN Wilking","year":"2013","unstructured":"Wilking JN, Zaburdaev V, De Volder M, Losick R, Brenner MP, Weitz DA (2013) Liquid transport facilitated by channels in Bacillus subtilis biofilms. Proc Natl Acad Sci U S A 110(3):848\u2013852. https:\/\/doi.org\/10.1073\/pnas.1216376110","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"2","key":"2222_CR17","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1046\/j.1365-313X.1997.12020427.x","volume":"12","author":"CL Wymer","year":"1997","unstructured":"Wymer CL, Bibikova TN, Gilroy S (1997) Cytoplasmic free calcium distributions during the development of root hairs of Arabidopsis thaliana. Plant J 12(2):427\u2013439. https:\/\/doi.org\/10.1046\/j.1365-313X.1997.12020427.x","journal-title":"Plant J"}],"container-title":["Antonie van Leeuwenhoek"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10482-025-02222-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10482-025-02222-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10482-025-02222-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T18:02:10Z","timestamp":1768240930000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10482-025-02222-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,11]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["2222"],"URL":"https:\/\/doi.org\/10.1007\/s10482-025-02222-5","relation":{},"ISSN":["0003-6072","1572-9699"],"issn-type":[{"value":"0003-6072","type":"print"},{"value":"1572-9699","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,11]]},"assertion":[{"value":"28 August 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 December 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 December 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"We report on the oscillatory expansion of\n                      Bacillus subtilis\n                      biofilms, demonstrating how these dynamics are modulated by glutamate and agar concentrations, competition, and self-healing. The developed spatial\u2013temporal and computational model validated the experimental findings.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Importance"}}],"article-number":"9"}}