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This study aims to investigate the effects of NF therapy on QoL and self-efficacy in cancer patients and to explore age-related reactions. In a waitlist control paradigm, psychometric data (<jats:italic>EORTC QLQ-C30, General Self-Efficacy Scale<\/jats:italic>) of 20 patients were collected at three different time points, each five weeks apart. An outpatient 10-session NF intervention (mobile) was conducted between the second and third measurement point. QoL and self-efficacy changed significantly over time (QoL: <jats:italic>F<\/jats:italic>(2,36)\u2009=\u20095.294, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05, <jats:italic>\u03b7<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u2009.227; Self-efficacy: <jats:italic>F<\/jats:italic>(2,26)\u2009=\u20098.178, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05, <jats:italic>\u03b7<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u2009.386). While QoL increased in younger patients, older patients initially showed a decrease in QoL, which then increased during intervention. Younger patients did not differ from older patients in QoL in both waitlist control (T0-T1) and intervention phase (T1\u2013T2). QoL in older patients significantly differed between waitlist control and intervention phase (<jats:italic>Z<\/jats:italic>\u2009=\u2009\u2212\u00a02.023, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05, <jats:italic>d<\/jats:italic>\u2009=\u20091.085). Self-efficacy increased in both age categories. Younger and older patients did not differ in self-efficacy in waitlist control, but in intervention phase (<jats:italic>F<\/jats:italic>(1,16)\u2009=\u20097.014, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05, <jats:italic>\u03b7<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u2009.319). The current findings suggest that NF therapy is a promising treatment modality for improving QoL in cancer patients. Our study reveals NF being a tool to influence self-efficacy, which should receive more appreciation in clinical care. However, the effect of NF in different age groups as well as the influence on further cancer-related symptoms should be investigated in future research.\n<\/jats:p>","DOI":"10.1007\/s10484-022-09571-1","type":"journal-article","created":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T20:05:14Z","timestamp":1668801914000},"page":"217-227","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Cancer Patients\u2019 Age-Related Benefits from Mobile Neurofeedback-Therapy in Quality of Life and Self-efficacy: A Clinical Waitlist Control Study"],"prefix":"10.1007","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2308-509X","authenticated-orcid":false,"given":"Kira","family":"Schmidt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marvin","family":"Krawutschke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Axel","family":"Kowalski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saskia","family":"Pasche","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Bialek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theresa","family":"Schweig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Weism\u00fcller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitra","family":"Tewes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Schuler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rainer","family":"Hamacher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernhard W.","family":"M\u00fcller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dirk","family":"Schadendorf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva-Maria","family":"Skoda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Teufel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madeleine","family":"Fink","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,11,18]]},"reference":[{"issue":"5","key":"9571_CR1","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1093\/jnci\/85.5.365","volume":"85","author":"NK Aaronson","year":"1993","unstructured":"Aaronson, N. 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