{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T01:43:41Z","timestamp":1793324621302,"version":"4.5.0"},"reference-count":59,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T00:00:00Z","timestamp":1700524800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T00:00:00Z","timestamp":1700524800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31802008"],"award-info":[{"award-number":["31802008"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003787","name":"Natural Science Foundation of Hebei Province","doi-asserted-by":"publisher","award":["C2022205019"],"award-info":[{"award-number":["C2022205019"]}],"id":[{"id":"10.13039\/501100003787","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Exp Appl Acarol"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1007\/s10493-023-00858-4","type":"journal-article","created":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T15:03:18Z","timestamp":1700578998000},"page":"681-695","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Mechanism of the toxic effects of tetracycline on blood meal digestion in Haemaphysalis longicornis"],"prefix":"10.1007","volume":"91","author":[{"given":"Yan-Kai","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si-Si","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Fan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing-Ze","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,11,21]]},"reference":[{"key":"858_CR1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2021.710352","volume":"8","author":"H Aguilar-D\u00edaz","year":"2021","unstructured":"Aguilar-D\u00edaz H, Quiroz-Casta\u00f1eda RE, Cobaxin-C\u00e1rdenas M, Salinas-Estrella E, Amaro-Estrada I (2021) Advances in the study of the tick cattle microbiota and the influence on vectorial capacity. Front Vet Sci 8:710352","journal-title":"Front Vet Sci"},{"key":"858_CR2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pestbp.2021.104971","volume":"179","author":"DO Agwunobi","year":"2021","unstructured":"Agwunobi DO, Zhang M, Zhang X, Wang T, Yu Z, Liu J (2021) Transcriptome profile of Haemaphysalis longicornis (Acari: Ixodidae) exposed to Cymbopogon citratus essential oil and citronellal suggest a cytotoxic mode of action involving mitochondrial Ca2+ overload and depolarization. Pest Biochem Physiol 179:104971","journal-title":"Pest Biochem Physiol"},{"key":"858_CR3","doi-asserted-by":"publisher","first-page":"236","DOI":"10.3389\/fcimb.2017.00236","volume":"7","author":"SI Bonnet","year":"2017","unstructured":"Bonnet SI, Binetruy F, Hern\u00e1ndez-Jargu\u00edn AM, Duron O (2017) The tick microbiome: why non-pathogenic microorganisms matter in tick biology and pathogen transmission. Front Cell Infect Microbiol 7:236","journal-title":"Front Cell Infect Microbiol"},{"key":"858_CR4","doi-asserted-by":"publisher","first-page":"W317","DOI":"10.1093\/nar\/gkab447","volume":"49","author":"D Bu","year":"2021","unstructured":"Bu D, Luo H, Huo P, Wang Z, Zhang S, He Z, Wu Y, Zhao L, Liu J, Guo J, Fang S, Cao W, Yi L, Zhao Y, Kong L (2021) KOBAS-i: intelligent prioritization and exploratory visualization of biological functions for gene enrichment analysis. Nucleic Ncids Res 49:W317\u2013W325","journal-title":"Nucleic Ncids Res"},{"key":"858_CR5","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1128\/MMBR.65.2.232-260.2001","volume":"65","author":"I Chopra","year":"2001","unstructured":"Chopra I, Roberts M (2001) Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance. Microbiol Mol Biol Rev 65:232\u2013260","journal-title":"Microbiol Mol Biol Rev"},{"key":"858_CR6","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-30197-1239","author":"T Coenye","year":"2014","unstructured":"Coenye T (2014) The family burkholderiaceae. Prokaryotes. https:\/\/doi.org\/10.1007\/978-3-642-30197-1239","journal-title":"Prokaryotes"},{"key":"858_CR7","doi-asserted-by":"publisher","first-page":"1896","DOI":"10.1016\/j.cub.2018.04.038","volume":"28","author":"O Duron","year":"2018","unstructured":"Duron O, Morel O, No\u00ebl V, Buysse M, Binetruy F, Lancelot R, Loire E, Menard C, Bouchez O, Vavre F, Vial L (2018) Tick-bacteria mutualism depends on B vitamin synthesis pathways. Curr Biol 28:1896\u20131902","journal-title":"Curr Biol"},{"key":"858_CR8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1756-3305-3-119","volume":"3","author":"Z Franta","year":"2010","unstructured":"Franta Z, Frantov\u00e1 H, Konvi\u010dkov\u00e1 J, Horn M, Sojka D, Mare\u0161 M, Kop\u00e1\u010dek P (2010) Dynamics of digestive proteolytic system during blood feeding of the hard tick Ixodes ricinus. Parasite Vector 3:1\u201311","journal-title":"Parasite Vector"},{"key":"858_CR9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13071-022-05638-4","volume":"16","author":"G Grandi","year":"2023","unstructured":"Grandi G, Chiappa G, Ullman K, Lindgren PE, Olivieri E, Sassera D, \u00d6stlund E, Omazic A, Perissinotto D, S\u00f6derlund R (2023) Characterization of the bacterial microbiome of Swedish ticks through 16S rRNA amplicon sequencing of whole ticks and of individual tick organs. Parasite Vector 16:1\u201310","journal-title":"Parasite Vector"},{"key":"858_CR10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-017-17309-x","volume":"7","author":"MG Guizzo","year":"2017","unstructured":"Guizzo MG, Parizi LF, Nunes RD, Schama R, Albano RM, Tirloni L, Oldiges DP, Vieira RP, Oloveira WHC, Leite MS, Gonzales SA, Farber M, Martins O Jr, Oliveira PL (2017) A Coxiella mutualist symbiont is essential to the development of Rhipicephalus microplus. Sci Rep 7:1\u201310","journal-title":"Sci Rep"},{"key":"858_CR11","doi-asserted-by":"publisher","first-page":"211","DOI":"10.3389\/fcimb.2020.00211","volume":"10","author":"MG Guizzo","year":"2020","unstructured":"Guizzo MG, Neupane S, Kucera M, Perner J, Frantov\u00e1 H, da Silva VI, de Oliveira PL, Kopacek P, Zurek L (2020) Poor unstable midgut microbiome of hard ticks contrasts with abundant and stable monospecific microbiome in ovaries. Front Cell Infect Microbiol 10:211","journal-title":"Front Cell Infect Microbiol"},{"key":"858_CR12","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1186\/s13071-022-05362-z","volume":"15","author":"MG Guizzo","year":"2022","unstructured":"Guizzo MG, Dolezelikova K, Neupane S, Frantova H, Hrbatova A, Pafco B, Fiorotti J, Kopacek P, Zurek L (2022) Characterization and manipulation of the bacterial community in the midgut of Ixodes ricinus. Parasite Vector 15:248","journal-title":"Parasite Vector"},{"key":"858_CR13","doi-asserted-by":"publisher","first-page":"1930","DOI":"10.3389\/fcimb.2022.1081666","volume":"12","author":"MG Guizzo","year":"2023","unstructured":"Guizzo MG, Hatalov\u00e1 T, Frantov\u00e1 H, Zurek L, Kop\u00e1\u010dek P, Perner J (2023) Ixodes ricinus ticks have a functional association with Midichloria mitochondrii. Front Cell Infect Microbiol 12:1930","journal-title":"Front Cell Infect Microbiol"},{"key":"858_CR14","first-page":"38","volume":"37","author":"B Havelkova","year":"2016","unstructured":"Havelkova B, Beklova M, Kovacova V, Hlavkova D, Pikula J (2016) Ecotoxicity of selected antibiotics for organisms of aquatic and terrestrial ecosystems. Neuroendocrinol Lett 37:38\u201344","journal-title":"Neuroendocrinol Lett"},{"key":"858_CR15","doi-asserted-by":"publisher","DOI":"10.1016\/j.dci.2019.103409","volume":"100","author":"EP Hernandez","year":"2019","unstructured":"Hernandez EP, Talactac MR, Fujisaki K, Tanaka T (2019) The case for oxidative stress molecule involvement in the tick-pathogen interactions-an omics approach. Dev Comp Immunol 100:103409","journal-title":"Dev Comp Immunol"},{"key":"858_CR16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2022.114049","volume":"244","author":"L Hou","year":"2022","unstructured":"Hou L, Fu Y, Zhao C, Fan L, Hu H, Yin S (2022) Ciprofloxacin and enrofloxacin can cause reproductive toxicity via endocrine signaling pathways. Ecotox Environ Safe 244:114049","journal-title":"Ecotox Environ Safe"},{"key":"858_CR17","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1016\/j.mib.2019.10.008","volume":"51","author":"MI Hutchings","year":"2019","unstructured":"Hutchings MI, Truman AW, Wilkinson B (2019) Antibiotics: past, present and future. Curr Opin Microbiol 51:72\u201380","journal-title":"Curr Opin Microbiol"},{"key":"858_CR18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cell.2020.05.008","volume":"182","author":"Jia N, Wang J, Shi W, Du L, Sun Y, Zhan W, Jiang JF, Wang Q, Zhang B, Ji P, Bell-Sakyi L, Cui XM, Yuan TT, Jiang BG, Yang WF, Lam TT, Chang QC, Ding SJ, Wang XJ, Zhu JG, Ruan XD, Zhao L, Wei JT, Ye RZ, Que TC, Du CH, Zhou YH, Cheng JX, Dai PF, Guo WB, Han XH, Huang EJ, Wei W, Gao YC, Liu JZ, Shao HZ, Wang X, Wang CC, Yang TC, Huo QB, Li W, Chen HY, Chen SE, Zhou LG, Bi XB, Tian JH, Sheng Y, Liu T, Pan YS, Xia LY, Li J, Tick Genome and Microbiome Consortium, Zhao F, Cao WC","year":"2020","unstructured":"Jia N, Wang J, Shi W, Du L, Sun Y, Zhan W, Jiang JF, Wang Q, Zhang B, Ji P, Bell-Sakyi L, Cui XM, Yuan TT, Jiang BG, Yang WF, Lam TT, Chang QC, Ding SJ, Wang XJ, Zhu JG, Ruan XD, Zhao L, Wei JT, Ye RZ, Que TC, Du CH, Zhou YH, Cheng JX, Dai PF, Guo WB, Han XH, Huang EJ, Wei W, Gao YC, Liu JZ, Shao HZ, Wang X, Wang CC, Yang TC, Huo QB, Li W, Chen HY, Chen SE, Zhou LG, Bi XB, Tian JH, Sheng Y, Liu T, Pan YS, Xia LY, Li J, Tick Genome and Microbiome Consortium, Zhao F, Cao WC (2020) Large-scale comparative analyses of tick genomes elucidate their genetic diversity and vector capacities. Cell 182:1\u201313","journal-title":"Cell"},{"key":"858_CR19","doi-asserted-by":"publisher","first-page":"1341","DOI":"10.1007\/s00436-011-2429-x","volume":"109","author":"S Kawano","year":"2011","unstructured":"Kawano S, Umemiya-Shirafuji R, Boldbaatar D, Matsuoka K, Tanaka T, Fujisaki K (2011) Cloning and characterization of the autophagy-related gene 6 from the hard tick, Haemaphysalis longicornis. Parasitol Res 109:1341\u20131349","journal-title":"Parasitol Res"},{"key":"858_CR20","volume-title":"HISAT2: graph-based alignment of next-generation sequencing reads to a population of genomes","author":"D Kim","year":"2017","unstructured":"Kim D, Langmead B, Salzberg S (2017) HISAT2: graph-based alignment of next-generation sequencing reads to a population of genomes. Center for Computational Biology, Johns Hopkins University, Baltimore"},{"key":"858_CR21","doi-asserted-by":"publisher","DOI":"10.1002\/9783527802883.ch7","author":"P Kop\u00e1\u010dek","year":"2018","unstructured":"Kop\u00e1\u010dek P, Perner J, Sojka D, \u0160\u00edma R, Hajdu\u0161ek O (2018) Molecular targets to impair blood meal processing in ticks. Ectoparasites. https:\/\/doi.org\/10.1002\/9783527802883.ch7","journal-title":"Ectoparasites"},{"key":"858_CR22","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2020.126351","volume":"251","author":"P Kovalakova","year":"2020","unstructured":"Kovalakova P, Cizmas L, McDonald TJ, Marsalek B, Feng M, Sharma VK (2020) Occurrence and toxicity of antibiotics in the aquatic environment: a review. Chemosphere 251:126351","journal-title":"Chemosphere"},{"key":"858_CR23","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0104815","volume":"9","author":"AH Kurlovs","year":"2014","unstructured":"Kurlovs AH, Li J, Cheng D, Zhong J (2014) Ixodes pacificus ticks maintain embryogenesis and egg hatching after antibiotic treatment of Rickettsia endosymbiont. PLoS ONE 9:e104815","journal-title":"PLoS ONE"},{"key":"858_CR24","doi-asserted-by":"publisher","first-page":"3093","DOI":"10.1242\/jeb.01749","volume":"208","author":"FA Lara","year":"2005","unstructured":"Lara FA, Lins U, Bechara GH, Oliveira PL (2005) Tracing heme in a living cell: hemoglobin degradation and heme traffic in digest cells of the cattle tick Boophilus microplus. J Exp Biol 208:3093\u20133101","journal-title":"J Exp Biol"},{"key":"858_CR25","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1471-2105-12-323","volume":"12","author":"B Li","year":"2011","unstructured":"Li B, Dewey CN (2011) RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. BMC Bioinform 12:1\u201316","journal-title":"BMC Bioinform"},{"key":"858_CR26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13071-018-2807-7","volume":"11","author":"LH Li","year":"2018","unstructured":"Li LH, Zhang Y, Zhu D (2018) Effects of antibiotic treatment on the fecundity of Rhipicephalus haemaphysaloides ticks. Parasite Vector 11:1\u20137","journal-title":"Parasite Vector"},{"key":"858_CR27","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2022.129628","volume":"439","author":"J Li","year":"2022","unstructured":"Li J, Li W, Liu K, Guo Y, Ding C, Han J, Li P (2022a) Global review of macrolide antibiotics in the aquatic environment: Sources, occurrence, fate, ecotoxicity, and risk assessment. J Hazard Mater 439:129628","journal-title":"J Hazard Mater"},{"key":"858_CR28","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1007\/s10493-022-00714-x","volume":"87","author":"SS Li","year":"2022","unstructured":"Li SS, Zhang XY, Zhou XJ, Chen KL, Masoudi A, Liu JZ, Zhang YK (2022b) Bacterial microbiota analysis demonstrates that ticks can acquire bacteria from habitat and host blood meal. Exp Appl Acarol 87:81\u201395","journal-title":"Exp Appl Acarol"},{"key":"858_CR29","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1007\/s10493-005-1271-1","volume":"36","author":"J Liu","year":"2005","unstructured":"Liu J, Liu Z, Zhang Y, Yang X, Gao Z (2005) Biology of Dermacentor silvarum (Acari: Ixodidae) under laboratory conditions. Exp Appl Acarol 36:131\u2013138","journal-title":"Exp Appl Acarol"},{"key":"858_CR30","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2022.132383","volume":"369","author":"C Liu","year":"2022","unstructured":"Liu C, Li B, Liu M, Mao S (2022) Demand, status, and prospect of antibiotics detection in the environment. Sensor Actuat B 369:132383","journal-title":"Sensor Actuat B"},{"key":"858_CR31","doi-asserted-by":"publisher","first-page":"148","DOI":"10.3389\/fvets.2017.00148","volume":"4","author":"I Magouras","year":"2017","unstructured":"Magouras I, Carmo LP, St\u00e4rk KD, Sch\u00fcpbach-Regula G (2017) Antimicrobial usage and-resistance in livestock: where should we focus? Front Vet Sci 4:148","journal-title":"Front Vet Sci"},{"key":"858_CR32","doi-asserted-by":"publisher","first-page":"575","DOI":"10.4161\/auto.6.5.11962","volume":"6","author":"D Malagoli","year":"2010","unstructured":"Malagoli D, Abdalla FC, Cao Y, Feng Q, Fujisaki K, Gregorc A, Matsuo T, Nezis IP, Papassideri IS, Sass M, Silva-Zacarin ECM, Tettamanti G, Umemiya-Shirafuji R (2010) Autophagy and its physiological relevance in arthropods: current knowledge and perspectives. Autophagy 6:575\u2013588","journal-title":"Autophagy"},{"key":"858_CR33","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1126\/science.1159483","volume":"321","author":"JL Mart\u00ednez","year":"2008","unstructured":"Mart\u00ednez JL (2008) Antibiotics and antibiotic resistance genes in natural environments. Science 321:365\u2013367","journal-title":"Science"},{"key":"858_CR34","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.parint.2016.10.011","volume":"66","author":"HNS Moreira","year":"2017","unstructured":"Moreira HNS, Barcelos RM, Vidigal PMP, Klein RC, Montandon CE, Maciel TEF, Carrizo JFA, de Lima PHC, Soares AC, Martins MM, Mafra C (2017) A deep insight into the whole transcriptome of midguts, ovaries and salivary glands of the Amblyomma sculptum tick. Parasitol Int 66:64\u201373","journal-title":"Parasitol Int"},{"key":"858_CR35","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.chom.2013.12.001","volume":"15","author":"S Narasimhan","year":"2014","unstructured":"Narasimhan S, Rajeevan N, Liu L, Zhao YO, Heisig J, Pan J, Eppler-Epstein R, DePonte K, Fish D, Fikrig E (2014) Gut microbiota of the tick vector Ixodes scapularis modulate colonization of the Lyme disease spirochete. Cell Host Microbe 15:58\u201371","journal-title":"Cell Host Microbe"},{"key":"858_CR36","doi-asserted-by":"publisher","first-page":"722","DOI":"10.1016\/j.pt.2021.04.004","volume":"37","author":"S Narasimhan","year":"2021","unstructured":"Narasimhan S, Swei A, Abouneameh S, Pal U, Pedra JH, Fikrig E (2021) Grappling with the tick microbiome. Trends Parasitol 37:722\u2013733","journal-title":"Trends Parasitol"},{"key":"858_CR37","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1016\/j.ttbdis.2015.05.011","volume":"6","author":"C Ninio","year":"2015","unstructured":"Ninio C, Plantard O, Serra V, Pollera C, Ferrari N, Cafiso A, Sassera D, Bazzocchi C (2015) Antibiotic treatment of the hard tick Ixodes ricinus: influence on Midichloria mitochondrii load following blood meal. Ticks Tick-Borne Dis 6:653\u2013657","journal-title":"Ticks Tick-Borne Dis"},{"key":"858_CR38","doi-asserted-by":"publisher","first-page":"298","DOI":"10.3389\/fcimb.2019.00298","volume":"9","author":"D Obreg\u00f3n","year":"2019","unstructured":"Obreg\u00f3n D, Bard E, Abrial D, Estrada-Pe\u00f1a A, Cabezas-Cruz A (2019) Sex-specific linkages between taxonomic and functional profiles of tick gut microbiomes. Front Cell Infect Microbiol 9:298","journal-title":"Front Cell Infect Microbiol"},{"key":"858_CR39","doi-asserted-by":"publisher","first-page":"e01672","DOI":"10.1128\/AEM.01672-20","volume":"87","author":"JD Oliver","year":"2021","unstructured":"Oliver JD, Price LD, Burkhardt NY, Heu CC, Khoo BS, Thorpe CJ, Kuerri TJ, Munderloh UG (2021) Growth dynamics and antibiotic elimination of symbiotic Rickettsia buchneri in the tick Ixodes scapularis (Acari: Ixodidae). Appl Environ Microbiol 87:e01672-e1720","journal-title":"Appl Environ Microbiol"},{"key":"858_CR40","doi-asserted-by":"publisher","DOI":"10.1016\/j.ttbdis.2022.102033","volume":"13","author":"A Pathak","year":"2022","unstructured":"Pathak A, Chakraborty S, Oyen K, Rosendale AJ, Benoit JB (2022) Dual assessment of transcriptional and metabolomic responses in the American dog tick following exposure to different pesticides and repellents. Ticks Tick-Borne Dis 13:102033","journal-title":"Ticks Tick-Borne Dis"},{"key":"858_CR41","doi-asserted-by":"publisher","first-page":"36695","DOI":"10.1038\/srep36695","volume":"6","author":"J Perner","year":"2016","unstructured":"Perner J, Provazn\u00edk J, Schrenkov\u00e1 J, Urbanov\u00e1 V, Ribeiro JM, Kop\u00e1\u010dek P (2016) RNA-seq analyses of the midgut from blood-and serum-fed Ixodes ricinus ticks. Sci Rep 6:36695","journal-title":"Sci Rep"},{"key":"858_CR42","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1038\/nbt.3122","volume":"33","author":"M Pertea","year":"2015","unstructured":"Pertea M, Pertea GM, Antonescu CM, Chang TC, Mendell JT, Salzberg SL (2015) StringTie enables improved reconstruction of a transcriptome from RNA-seq reads. Nat Biotechnol 33:290\u2013295","journal-title":"Nat Biotechnol"},{"key":"858_CR43","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1002\/dvg.22717","volume":"51","author":"VT Santos","year":"2013","unstructured":"Santos VT, Ribeiro L, Fraga A, de Barros CM, Campos E, Moraes J, Fontenele MR, Ara\u00fajo HM, Feitosa NM, Logullo C, da Fonseca RN (2013) The embryogenesis of the tick Rhipicephalus (Boophilus) microplus: the establishment of a new chelicerate model system. Genesis 51:803\u2013818","journal-title":"Genesis"},{"key":"858_CR44","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2021.149205","volume":"798","author":"Y Shao","year":"2021","unstructured":"Shao Y, Wang Y, Yuan Y, Xie Y (2021) A systematic review on antibiotics misuse in livestock and aquaculture and regulation implications in China. Sci Total Environ 798:149205","journal-title":"Sci Total Environ"},{"key":"858_CR45","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1016\/j.pt.2013.04.002","volume":"29","author":"D Sojka","year":"2013","unstructured":"Sojka D, Franta Z, Horn M, Caffrey CR, Mare\u0161 M, Kop\u00e1\u010dek P (2013) New insights into the machinery of blood digestion by ticks. Trends Parasitol 29:276\u2013285","journal-title":"Trends Parasitol"},{"key":"858_CR46","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1038\/nrmicro2974","volume":"11","author":"F Sommer","year":"2013","unstructured":"Sommer F, B\u00e4ckhed F (2013) The gut microbiota\u2014masters of host development and physiology. Nat Rev Microbiol 11:227\u2013238","journal-title":"Nat Rev Microbiol"},{"key":"858_CR47","volume-title":"Biology of ticks","year":"2013","unstructured":"Sonenshine DE, Roe RM (eds) (2013) Biology of ticks, vol 2. Oxford University Press, Oxford"},{"key":"858_CR48","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0016682","volume":"6","author":"G Vandenborre","year":"2011","unstructured":"Vandenborre G, Smagghe G, Ghesquiere B, Menschaert G, Nagender Rao R, Gevaert K, Van Damme EJ (2011) Diversity in protein glycosylation among insect species. PLoS ONE 6:e16682","journal-title":"PLoS ONE"},{"key":"858_CR49","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2022.784430","volume":"12","author":"XR Wang","year":"2022","unstructured":"Wang XR, Cull B (2022) Apoptosis and autophagy: current understanding in tick-pathogen interactions. Front Cell Infect Microbiol 12:784430","journal-title":"Front Cell Infect Microbiol"},{"key":"858_CR50","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1093\/bioinformatics\/btp612","volume":"26","author":"L Wang","year":"2010","unstructured":"Wang L, Feng Z, Wang X, Wang X, Zhang X (2010) DEGseq: an R package for identifying differentially expressed genes from RNA-seq data. Bioinformatics 26:136\u2013138","journal-title":"Bioinformatics"},{"key":"858_CR51","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2021.713466","volume":"11","author":"N Wei","year":"2021","unstructured":"Wei N, Cao J, Zhang H, Zhou Y, Zhou J (2021) The tick microbiota dysbiosis promote tick-borne pathogen transstadial transmission in a Babesia microti\u2013infected mouse model. Front Cell Infect Microbiol 11:713466","journal-title":"Front Cell Infect Microbiol"},{"key":"858_CR52","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1128\/CMR.00004-09","volume":"22","author":"GP Wormser","year":"2009","unstructured":"Wormser GP, Schwartz I (2009) Antibiotic treatment of animals infected with Borrelia burgdorferi. Clin Microbiol Rev 22:387\u2013395","journal-title":"Clin Microbiol Rev"},{"key":"858_CR53","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.141975","volume":"753","author":"L Xu","year":"2021","unstructured":"Xu L, Zhang H, Xiong P, Zhu Q, Liao C, Jiang G (2021) Occurrence, fate, and risk assessment of typical tetracycline antibiotics in the aquatic environment: a review. Sci Total Environ 753:141975","journal-title":"Sci Total Environ"},{"key":"858_CR54","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1007\/s10493-017-0194-y","volume":"73","author":"CM Zhang","year":"2017","unstructured":"Zhang CM, Li NX, Zhang TT, Qiu ZX, Li Y, Li LW, Liu JZ (2017) Endosymbiont CLS-HI plays a role in reproduction and development of Haemaphysalis longicornis. Exp Appl Acarol 73:429\u2013438","journal-title":"Exp Appl Acarol"},{"key":"858_CR55","doi-asserted-by":"publisher","DOI":"10.1002\/ps.7766","author":"YK Zhang","year":"2023","unstructured":"Zhang YK, Li SS, Yang C, Zhang YF, Zhang XY, Liu JZ (2023) Tetracycline inhibit tick host reproduction by modulating bacterial microbiota, gene expression, and metabolism levels. Pest Manag Sci. https:\/\/doi.org\/10.1002\/ps.7766","journal-title":"Pest Manag Sci"},{"key":"858_CR56","doi-asserted-by":"publisher","first-page":"e320","DOI":"10.1016\/S2542-5196(20)30145-5","volume":"4","author":"L Zhao","year":"2020","unstructured":"Zhao L, Li J, Cui X, Jia N, Wei J, Xia L, Wang H, Zhou Y, Wang Q, Liu X, Yin C, Pan Y, Wen H, Wang Q, Xue F, Sun Y, Jiang J, Li S, Cao W (2020) Distribution of Haemaphysalis longicornis and associated pathogens: analysis of pooled data from a China field survey and global published data. Lancet Planet 4:e320\u2013e329","journal-title":"Lancet Planet"},{"key":"858_CR57","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1007\/s10493-010-9415-3","volume":"53","author":"H Zheng","year":"2011","unstructured":"Zheng H, Yu Z, Chen Z, Zhou L, Zheng B, Ma H, Liu J (2011) Development and biological characteristics of Haemaphysalis longicornis (Acari: Ixodidae) under field conditions. Exp Appl Acarol 53:377\u2013388","journal-title":"Exp Appl Acarol"},{"key":"858_CR58","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0000405","volume":"2","author":"J Zhong","year":"2007","unstructured":"Zhong J, Jasinskas A, Barbour AG (2007) Antibiotic treatment of the tick vector Amblyomma americanum reduced reproductive fitness. PLoS ONE 2:e405","journal-title":"PLoS ONE"},{"key":"858_CR59","doi-asserted-by":"publisher","first-page":"1545","DOI":"10.1016\/j.chom.2021.08.011","volume":"29","author":"Z Zhong","year":"2021","unstructured":"Zhong Z, Zhong T, Peng Y, Zhou X, Wang Z, Tang H, Wang J (2021) Symbiont-regulated serotonin biosynthesis modulates tick feeding activity. Cell Host Microbe 29:1545\u20131557","journal-title":"Cell Host Microbe"}],"container-title":["Experimental and Applied Acarology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10493-023-00858-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10493-023-00858-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10493-023-00858-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,30]],"date-time":"2023-11-30T10:12:27Z","timestamp":1701339147000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10493-023-00858-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,21]]},"references-count":59,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["858"],"URL":"https:\/\/doi.org\/10.1007\/s10493-023-00858-4","relation":{},"ISSN":["0168-8162","1572-9702"],"issn-type":[{"value":"0168-8162","type":"print"},{"value":"1572-9702","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,21]]},"assertion":[{"value":"30 August 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 October 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 November 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}