{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T12:16:28Z","timestamp":1761394588466},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2015,1,18]],"date-time":"2015-01-18T00:00:00Z","timestamp":1421539200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Apoptosis"],"published-print":{"date-parts":[[2015,3]]},"DOI":"10.1007\/s10495-014-1075-z","type":"journal-article","created":{"date-parts":[[2015,1,17]],"date-time":"2015-01-17T04:25:45Z","timestamp":1421468745000},"page":"410-420","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Evaluation of a dansyl-based amino acid DNSBA as an imaging probe for apoptosis detection"],"prefix":"10.1007","volume":"20","author":[{"given":"Min","family":"Tang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaguo","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinxian","family":"Weng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lifang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meihui","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaobo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinghe","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Yi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenbin","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lunquan","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ya","family":"Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,1,18]]},"reference":[{"key":"1075_CR1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/cmmi.458","volume":"7","author":"T Skotland","year":"2012","unstructured":"Skotland T (2012) Molecular imaging: challenges of bringing imaging of intracellular targets into common clinical use. Contrast Media Mol Imaging 7:1\u20136","journal-title":"Contrast Media Mol Imaging"},{"key":"1075_CR2","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1038\/nrc2663","volume":"9","author":"TG Cotter","year":"2009","unstructured":"Cotter TG (2009) Apoptosis and cancer: the genesis of a research field. Nat Rev Cancer 9:501\u2013507","journal-title":"Nat Rev Cancer"},{"key":"1075_CR3","doi-asserted-by":"crossref","first-page":"178","DOI":"10.3322\/canjclin.55.3.178","volume":"55","author":"I Ghobrial","year":"2005","unstructured":"Ghobrial I, Witzig T, Adjei A (2005) Targeting apoptosis pathways in cancer therapy. CA Cancer J Clin 55:178\u2013194","journal-title":"CA Cancer J Clin"},{"key":"1075_CR4","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1146\/annurev.med.57.080904.190431","volume":"57","author":"J Czernin","year":"2006","unstructured":"Czernin J, Weber WA, Herschman HR (2006) Molecular imaging in the development of cancer therapeutics. Annu Rev Med 57:99\u2013118","journal-title":"Annu Rev Med"},{"key":"1075_CR5","first-page":"1936","volume":"63","author":"A Petrovsky","year":"2003","unstructured":"Petrovsky A, Schellenberger E, Josephson L, Weissleder R, Bogdanov A (2003) Near-infrared fluorescent imaging of tumor apoptosis. Cancer Res 63:1936\u20131942","journal-title":"Cancer Res"},{"key":"1075_CR6","doi-asserted-by":"crossref","first-page":"6349","DOI":"10.1073\/pnas.95.11.6349","volume":"95","author":"FG Blankenberg","year":"1998","unstructured":"Blankenberg FG, Katsikis PD, Tait JF, Davis RE, Naumovski L, Ohtsuki K, Kopiwoda S, Abrams MJ, Darkes M, Robbins RC (1998) In vivo detection and imagin of phosphatidylserine expression during programmed cell death. Proc Natl Acad Sci USA 95:6349\u20136354","journal-title":"Proc Natl Acad Sci USA"},{"key":"1075_CR7","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.drudis.2012.02.002","volume":"17","author":"NO Carragher","year":"2012","unstructured":"Carragher NO, Brunton VG, Frame MC (2012) Combining imaging and pathway profiling: an alternative approach to cancer drug discovery. Drug Discov Today 17:203\u2013214","journal-title":"Drug Discov Today"},{"key":"1075_CR8","doi-asserted-by":"crossref","first-page":"5041","DOI":"10.1016\/j.bmcl.2006.07.045","volume":"16","author":"D Zhou","year":"2006","unstructured":"Zhou D, Chu W, Rothfuss J, Zeng C, Xu J, Jones L, Welch M, Mach R (2006) Synthesis, radiolabeling, and in vivo evaluation of an 18F-labeled isatin analog for imaging caspase-3 activation in apoptosis. Bioorg Med Chem Lett 16:5041\u20135048","journal-title":"Bioorg Med Chem Lett"},{"key":"1075_CR9","doi-asserted-by":"crossref","first-page":"2089","DOI":"10.1007\/s10495-006-0282-7","volume":"11","author":"R Aloya","year":"2006","unstructured":"Aloya R, Shirvan A, Grimberg H, Reshef A, Levin G, Kidron D, Cohen A, Ziv I (2006) Molecular imaging of cell death in vivo by a novel small molecule probe. Apoptosis 11:2089\u20132101","journal-title":"Apoptosis"},{"key":"1075_CR10","doi-asserted-by":"crossref","first-page":"11003","DOI":"10.1073\/pnas.0604507103","volume":"103","author":"W Wang","year":"2006","unstructured":"Wang W, Kim S, El-Deiry W (2006) Small-molecule modulators of p53 family signaling and antitumor effects in p53-deficient human colon tumor xenografts. Proc Nat Acad Sci USA 103:11003\u201311008","journal-title":"Proc Nat Acad Sci USA"},{"key":"1075_CR11","doi-asserted-by":"crossref","first-page":"3490","DOI":"10.1021\/ja057712f","volume":"128","author":"K Kim","year":"2006","unstructured":"Kim K, Lee M, Park H, Kim J, Kim S, Chung H, Choi K, Kim I, Seong B, Kwon I (2006) Cell-permeable and biocompatible polymeric nanoparticles for apoptosis imaging. J Am Chem Soc 128:3490\u20133491","journal-title":"J Am Chem Soc"},{"key":"1075_CR12","doi-asserted-by":"crossref","first-page":"3573","DOI":"10.1016\/j.bmcl.2008.05.002","volume":"18","author":"W Zeng","year":"2008","unstructured":"Zeng W, Yao ML, Townsend D, Kabalka GW, Wall J, Puil ML, Biggerstaff J, Miao W (2008) Synthesis, biological evaluation and radiochemical labeling of a dansylhydrazone derivative as a potential imaging agent for apoptosis. Bioorg Med Chem Lett 18:3573\u20133577","journal-title":"Bioorg Med Chem Lett"},{"key":"1075_CR13","doi-asserted-by":"crossref","first-page":"986","DOI":"10.2174\/187152009789377763","volume":"9","author":"W Zeng","year":"2009","unstructured":"Zeng W, Miao W (2009) Development of small molecular probes for the molecular imaging of apoptosis. Anticancer Agents Med Chem 9:986\u2013995","journal-title":"Anticancer Agents Med Chem"},{"key":"1075_CR14","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.bbrc.2010.06.120","volume":"398","author":"W Zeng","year":"2010","unstructured":"Zeng W, Miao W, Le Puil M, Shi G, Biggerstaff J, Kabalka GW, Townsend D (2010) Design, synthesis, and biological evaluation of 4-(5-dimethylamino-naphthalene-1-sulfon-amido)-3-(4-iodophenyl) butanoic acid as a novel molecular probe for apoptosis imaging. Biochem Biophys Res Commun 398:571\u2013575","journal-title":"Biochem Biophys Res Commun"},{"key":"1075_CR15","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1038\/ncb0311-184","volume":"13","author":"I Tabas","year":"2011","unstructured":"Tabas I, Ron D (2011) Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress. Nat Cell Biol 13:184\u2013190","journal-title":"Nat Cell Biol"},{"key":"1075_CR16","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1038\/35037710","volume":"407","author":"MO Hengartner","year":"2000","unstructured":"Hengartner MO (2000) The biochemistry of apoptosis. Nature 407:770\u2013776","journal-title":"Nature"},{"key":"1075_CR17","first-page":"2035","volume":"46","author":"HH Boersma","year":"2005","unstructured":"Boersma HH, Kietselaer BL, Stolk LM, Bennaghmouch A, Hofstra L, Narula J, Heidendal G, Reutelingsperger C (2005) Past, present, and future of Annexin A5: from protein discovery to clinical applications. J Nucl Med 46:2035\u20132050","journal-title":"J Nucl Med"},{"key":"1075_CR18","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.nucmedbio.2010.09.008","volume":"38","author":"M Bauwens","year":"2011","unstructured":"Bauwens M, De Saint-Hubert M, Devos E, Deckers N, Reutelingsperger C, Mortelmans L, Himmelreich U, Mottaghy FM, Verbruggen A (2011) Site-specific 68\u00a0Ga-labeled Annexin A5 as a PET imaging agent for apoptosis. Nucl Med Biol 38:381\u2013392","journal-title":"Nucl Med Biol"},{"key":"1075_CR19","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1513\/pats.200901-001AW","volume":"6","author":"FG Blankenberg","year":"2009","unstructured":"Blankenberg FG (2009) Imaging the molecular signatures of apoptosis and injury with radiolabeled Annexin V. Proc Am Thorac Soc 6:469\u2013476","journal-title":"Proc Am Thorac Soc"},{"key":"1075_CR20","doi-asserted-by":"crossref","first-page":"4055","DOI":"10.1021\/bi061959n","volume":"46","author":"KE Bullok","year":"2007","unstructured":"Bullok KE, Maxwell D, Kesarwala AH, Gammon S, Prior JL, Snow M, Stanley S, Piwnica-Worms D (2007) Biochemical and in vivo characterization of a small, membrane-permeant, caspase-activatable far-red fluorescent peptide for imaging apoptosis. Biochemistry 46:4055\u20134065","journal-title":"Biochemistry"},{"key":"1075_CR21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.dyepig.2014.02.022","volume":"107","author":"J Huang","year":"2014","unstructured":"Huang J, Tang M, Liu M, Zhou M, Liu Z, Cao Y, Zhu M, Liu S, Zeng W (2014) Development of a fast responsive and highly sensitive fluorescent probe for Cu2+ ion and imaging in living cells. Dyes Pigment 107:1\u20138","journal-title":"Dyes Pigment"},{"key":"1075_CR22","first-page":"3","volume":"1","author":"X Huang","year":"2011","unstructured":"Huang X, Lee S, Chen X (2011) Design of \u201csmart\u201d probes for optical imaging of apoptosis. Am J Nucl Med Mol Imaging 1:3\u201317","journal-title":"Am J Nucl Med Mol Imaging"},{"key":"1075_CR23","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/s00259-005-1905-x","volume":"33","author":"M Damianovich","year":"2006","unstructured":"Damianovich M, Ziv I, Heyman SN, Rosen S, Shina A, Kidron D, Aloya T, Grimberg H, Levin G, Reshef A (2006) ApoSense: a novel technology for functional molecular imaging of cell death in models of acute renal tubular necrosis. Eur J Nucl Med Mol Imaging 33:281\u2013291","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"1075_CR24","doi-asserted-by":"crossref","first-page":"720","DOI":"10.2967\/jnumed.110.081786","volume":"52","author":"J Hoglund","year":"2011","unstructured":"Hoglund J, Shirvan A, Antoni G, Gustavsson S-\u00c5, L\u00e5ngstr\u00f6m B, Ringheim A, S\u00f6rensen J, Ben-Ami M, Ziv I (2011) 18F-ML-10, a PET tracer for apoptosis: first human study. J Nucl Med 52:720\u2013725","journal-title":"J Nucl Med"},{"key":"1075_CR25","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.2967\/jnumed.112.118760","volume":"54","author":"A Challapalli","year":"2013","unstructured":"Challapalli A, Kenny LM, Hallett WA, Kozlowski K, Tomasi G, Gudi M, Al-Nahhas A, Coombes RC, Aboagye EO (2013) 18F-ICMT-11, a caspase-3-specific PET tracer for apoptosis: biodistribution and radiation dosimetry. J Nucl Med 54:1551\u20131556","journal-title":"J Nucl Med"},{"key":"1075_CR26","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1007\/s11307-013-0646-7","volume":"15","author":"CF Xia","year":"2013","unstructured":"Xia CF, Chen G, Gangadharmath U, Gomez LF, Liang Q, Mu F, Mocharla VP, Su H, Szardenings AK, Walsh JC (2013) In vitro and in vivo evaluation of the caspase-3 substrate-based radiotracer [(18)F]-CP18 for PET imaging of apoptosis in tumors. Mol Imaging Biol 15:748\u2013757","journal-title":"Mol Imaging Biol"},{"key":"1075_CR27","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1007\/s11307-013-0644-9","volume":"15","author":"H Su","year":"2013","unstructured":"Su H, Chen G, Gangadharmath U, Gomez LF, Liang Q, Mu F, Mocharla VP, Szardenings AK, Walsh JC, Xia CF (2013) Evaluation of [(18)F]-CP18 as a PET imaging tracer for apoptosis. Mol Imaging Biol 15:739\u2013747","journal-title":"Mol Imaging Biol"}],"container-title":["Apoptosis"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10495-014-1075-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10495-014-1075-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10495-014-1075-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T18:41:35Z","timestamp":1559155295000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10495-014-1075-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,18]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["1075"],"URL":"https:\/\/doi.org\/10.1007\/s10495-014-1075-z","relation":{},"ISSN":["1360-8185","1573-675X"],"issn-type":[{"value":"1360-8185","type":"print"},{"value":"1573-675X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,18]]}}}