{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T18:13:36Z","timestamp":1784052816365,"version":"3.55.0"},"reference-count":313,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T00:00:00Z","timestamp":1781568000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T00:00:00Z","timestamp":1781568000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Apoptosis"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1007\/s10495-026-02375-2","type":"journal-article","created":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T13:18:02Z","timestamp":1781615882000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Programmed cell death and metastatic evolution in breast cancer: the role of anoikis, necroptosis, and ferroptosis"],"prefix":"10.1007","volume":"31","author":[{"given":"Alireza H.","family":"Shirvani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shirin","family":"Mohammadian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaghayegh","family":"Jamshidi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad H.","family":"Khodabandehloo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soheila","family":"Zangoie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romisa S.","family":"Moghadam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adel","family":"Amoozade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cena","family":"Aram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mona","family":"Rahimi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Javad","family":"Kamali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Alishvandi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,16]]},"reference":[{"issue":"6","key":"2375_CR1","first-page":"477","volume":"74","author":"AN Giaquinto","year":"2024","unstructured":"Giaquinto AN, Sung H, Newman LA, Freedman RA, Smith RA, Star J et al (2024) Breast cancer statistics 2024. CA Cancer J Clin 74(6):477\u2013495","journal-title":"CA Cancer J Clin"},{"issue":"16","key":"2375_CR2","doi-asserted-by":"publisher","first-page":"8854","DOI":"10.3390\/ijms25168854","volume":"25","author":"S Martinez","year":"2024","unstructured":"Martinez S, Sentis S, Poulard C, Tredan O, Le Romancer M (2024) Role of PRMT1 and PRMT5 in breast cancer. Int J Mol Sci 25(16):8854","journal-title":"Int J Mol Sci"},{"issue":"3","key":"2375_CR3","doi-asserted-by":"publisher","first-page":"267","DOI":"10.25259\/IJMR_1291_2024","volume":"161","author":"R Ursekar","year":"2025","unstructured":"Ursekar R, Chaubal R, Gandhi KA, Talker E, Chitra J, Raja A et al (2025) Circulating tumour DNA as a promising biomarker for breast cancer diagnosis & treatment monitoring. Indian J Med Res 161(3):267\u2013277","journal-title":"Indian J Med Res"},{"issue":"15","key":"2375_CR4","doi-asserted-by":"publisher","first-page":"1943","DOI":"10.2217\/fon-2020-1103","volume":"17","author":"K Mortezaee","year":"2021","unstructured":"Mortezaee K (2021) Organ tropism in solid tumor metastasis: an updated review. Future Oncol 17(15):1943\u20131961","journal-title":"Future Oncol"},{"issue":"1","key":"2375_CR5","doi-asserted-by":"publisher","first-page":"266","DOI":"10.3390\/ijms25010266","volume":"25","author":"F Du","year":"2023","unstructured":"Du F, Li Y, Xu K (2023) Phylogeny and evolution of Cocconeiopsis (Cocconeidaceae) as revealed by complete chloroplast and mitochondrial genomes. Int J Mol Sci 25(1):266","journal-title":"Int J Mol Sci"},{"issue":"2","key":"2375_CR6","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1007\/s12032-025-03217-y","volume":"43","author":"NAA Ebrahim","year":"2025","unstructured":"Ebrahim NAA, Farghaly TA, Soliman SMA (2025) Exosomal blueprint of lung-tropic metastasis: molecular signatures, microenvironmental conditioning, and translational implications in cancer. Med Oncol 43(2):93","journal-title":"Med Oncol"},{"issue":"12","key":"2375_CR7","doi-asserted-by":"publisher","first-page":"2482","DOI":"10.1111\/bph.15434","volume":"178","author":"M Arredondo-Amador","year":"2021","unstructured":"Arredondo-Amador M, Aranda CJ, Ocon B, Gonzalez R, Martinez-Augustin O, Sanchez de Medina F (2021) Epithelial deletion of the glucocorticoid receptor (Nr3c1) protects the mouse intestine against experimental inflammation. Br J Pharmacol 178(12):2482\u20132495","journal-title":"Br J Pharmacol"},{"issue":"1","key":"2375_CR8","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1007\/s10555-026-10318-1","volume":"45","author":"M Raudenska","year":"2026","unstructured":"Raudenska M, Balvan J, Zgarbova E, Kalfert D, Plzak J, Masarik M (2026) Shaping death: how the microbiome regulates tumour cell demise and therapy response. Cancer Metastasis Rev 45(1):9","journal-title":"Cancer Metastasis Rev"},{"key":"2375_CR9","doi-asserted-by":"crossref","unstructured":"Wen J, Li B, Wang S, Yao Y, Huang Z, Yu D (2026) Bone metastasis: molecular mechanisms, clinical management, and therapeutic targets. MedComm 7(2):e70604","DOI":"10.1002\/mco2.70604"},{"issue":"2","key":"2375_CR10","doi-asserted-by":"publisher","first-page":"579","DOI":"10.3390\/ijms27020579","volume":"27","author":"T Koltai","year":"2026","unstructured":"Koltai T, Fliegel L (2026) Anoikis: to die or not to die? Int J Mol Sci 27(2):579","journal-title":"Int J Mol Sci"},{"key":"2375_CR11","doi-asserted-by":"crossref","unstructured":"Li H, Song Y, Cong Y, Wang C, Chen K, Liu C et al (2026) YEATS2 promotes DNA repair and induces anoikis resistance by enhancing chromatin accessibility to drive prostate cancer metastasis. Oncogene, 1-18.","DOI":"10.1038\/s41388-026-03696-x"},{"issue":"1","key":"2375_CR12","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1186\/s12964-023-01183-4","volume":"21","author":"Y Dai","year":"2023","unstructured":"Dai Y, Zhang X, Ou Y, Zou L, Zhang D, Yang Q et al (2023) Anoikis resistance\u2013protagonists of breast cancer cells survive and metastasize after ECM detachment. Cell Commun Signal 21(1):190","journal-title":"Cell Commun Signal"},{"issue":"3","key":"2375_CR13","doi-asserted-by":"publisher","first-page":"1288","DOI":"10.3390\/ijms27031288","volume":"27","author":"R Kanwal","year":"2026","unstructured":"Kanwal R, Jawed B, Zakir SK, Gaudio F, Martinotti R, Botteghi M et al (2026) The anti-metastatic role of aspirin in cancer: a systematic review. Int J Mol Sci 27(3):1288","journal-title":"Int J Mol Sci"},{"key":"2375_CR14","doi-asserted-by":"publisher","first-page":"1737847","DOI":"10.3389\/fimmu.2026.1737847","volume":"17","author":"J Guo","year":"2026","unstructured":"Guo J, Wang Z, Zhang Y, Xie C, Chen Y, Ma L et al (2026) The dual roles of ferroptosis in digestive tract tumors: mechanisms, microenvironment regulation, and therapeutic integration with emphasis on immune interactions. Front Immunol 17:1737847","journal-title":"Front Immunol"},{"issue":"9","key":"2375_CR15","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1038\/s41419-023-06106-2","volume":"14","author":"S Chipurupalli","year":"2023","unstructured":"Chipurupalli S, Jiang P, Liu X, Santos JL, Marcato P, Rosen KV (2023) Three-dimensional growth sensitizes breast cancer cells to treatment with ferroptosis-promoting drugs. Cell Death Dis 14(9):580","journal-title":"Cell Death Dis"},{"key":"2375_CR16","doi-asserted-by":"publisher","first-page":"1629620","DOI":"10.3389\/fimmu.2025.1629620","volume":"16","author":"Z Shan","year":"2025","unstructured":"Shan Z, Liu F (2025) Targeting ferroptosis, pyroptosis and necroptosis for cancer immunotherapy in melanoma: mechanistic insights and clinical perspectives. Front Immunol 16:1629620","journal-title":"Front Immunol"},{"key":"2375_CR17","doi-asserted-by":"publisher","first-page":"119025","DOI":"10.1016\/j.biopha.2026.119025","volume":"195","author":"S Xiong","year":"2026","unstructured":"Xiong S, Hu L, Sun YY, Huang W, Hu XY (2026) RNA splicing dysregulation in hepatocellular carcinoma: molecular mechanisms, therapeutic targets, and intervention strategies-A comprehensive review. Biomed Pharmacother 195:119025","journal-title":"Biomed Pharmacother"},{"issue":"1","key":"2375_CR18","doi-asserted-by":"publisher","first-page":"3","DOI":"10.3390\/proteomes12010003","volume":"12","author":"D Fern\u00e1ndez-L\u00e1zaro","year":"2024","unstructured":"Fern\u00e1ndez-L\u00e1zaro D, Sanz B, Seco-Calvo J (2024) The mechanisms of regulated cell death: structural and functional proteomic pathways induced or inhibited by a specific protein\u2014a narrative review. Proteomes 12(1):3","journal-title":"Proteomes"},{"issue":"9\u201310","key":"2375_CR19","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1101\/gad.314674.118","volume":"32","author":"M Conrad","year":"2018","unstructured":"Conrad M, Kagan VE, Bayir H, Pagnussat GC, Head B, Traber MG et al (2018) Regulation of lipid peroxidation and ferroptosis in diverse species. Genes Dev 32(9\u201310):602\u2013619","journal-title":"Genes Dev"},{"key":"2375_CR20","doi-asserted-by":"crossref","unstructured":"Nghiem T-HT, Kusuma F, Park J, Joe Y, Chung HT, Han J (2025) Brief guide to detecting ferroptosis. Mol Cells 48:100276","DOI":"10.1016\/j.mocell.2025.100276"},{"issue":"23","key":"2375_CR21","doi-asserted-by":"publisher","first-page":"EMBJ2019103718","DOI":"10.15252\/embj.2019103718","volume":"40","author":"Z Liu","year":"2021","unstructured":"Liu Z, Dagley LF, Shield-Artin K, Young SN, Bankovacki A, Wang X et al (2021) Oligomerization-driven MLKL ubiquitylation antagonizes necroptosis. EMBO J 40(23):EMBJ2019103718","journal-title":"EMBO J"},{"issue":"3","key":"2375_CR22","doi-asserted-by":"publisher","first-page":"e694","DOI":"10.1002\/ctm2.694","volume":"12","author":"D Jovic","year":"2022","unstructured":"Jovic D, Liang X, Zeng H, Lin L, Xu F, Luo Y (2022) Single-cell RNA sequencing technologies and applications: a brief overview. Clin Transl Med 12(3):e694","journal-title":"Clin translational Med"},{"key":"2375_CR23","doi-asserted-by":"publisher","first-page":"1747560","DOI":"10.3389\/fimmu.2026.1747560","volume":"17","author":"W Li","year":"2026","unstructured":"Li W, Deng J, Zhang H, Zhang M, Kang C, Yu Z et al (2026) The role of disulfidptosis-driven tumor microenvironment remodeling in pancreatic cancer progression. Front Immunol 17:1747560","journal-title":"Front Immunol"},{"key":"2375_CR24","doi-asserted-by":"publisher","first-page":"109000","DOI":"10.1016\/j.pharmthera.2026.109000","volume":"281","author":"W Fang","year":"2026","unstructured":"Fang W, Luo W, Hu J, He Z, Liu X, Tang X et al (2026) Wnt signaling pathway: therapeutic target of natural products for cancer therapy. Pharmacol Ther 281:109000","journal-title":"Pharmacol Ther"},{"key":"2375_CR25","doi-asserted-by":"publisher","first-page":"113774","DOI":"10.1016\/j.biopha.2022.113774","volume":"155","author":"M Hashemi","year":"2022","unstructured":"Hashemi M, Arani HZ, Orouei S, Fallah S, Ghorbani A, Khaledabadi M et al (2022) EMT mechanism in breast cancer metastasis and drug resistance: revisiting molecular interactions and biological functions. Biomed Pharmacother 155:113774","journal-title":"Biomed Pharmacother"},{"issue":"1","key":"2375_CR26","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1038\/s41420-025-02743-y","volume":"11","author":"Y Wen","year":"2025","unstructured":"Wen Y, Lin Z, Jiang Z, Li Y, Wu T (2025) Targeting the redox-programmed cell death axis in breast cancer: from molecular mechanisms to therapeutic resistance. Cell Death Discov 11(1):441","journal-title":"Cell Death Discov"},{"key":"2375_CR27","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1126\/scisignal.abc6178","volume":"14","author":"AL Samson","year":"2021","unstructured":"Samson AL, Garnish SE, Hildebrand JM, Murphy JM (2021) Location, location, location: a compartmentalized view of TNF-induced necroptotic signaling. Sci Signal 14:668","journal-title":"Sci Signal"},{"issue":"1","key":"2375_CR28","doi-asserted-by":"publisher","first-page":"295","DOI":"10.18632\/oncotarget.28404","volume":"14","author":"Z Liu","year":"2023","unstructured":"Liu Z, Choksi S, Liu ZG (2023) Tumor necroptosis promotes metastasis through modulating the interplay between tumor and host immunity. Oncotarget 14(1):295\u2013296","journal-title":"Oncotarget"},{"issue":"7","key":"2375_CR29","doi-asserted-by":"publisher","first-page":"4379","DOI":"10.1007\/s11010-025-05262-7","volume":"480","author":"C Jiang","year":"2025","unstructured":"Jiang C, Yan Y, Long T, Xu J, Chang C, Kang M et al (2025) Ferroptosis: a potential therapeutic target in cardio-cerebrovascular diseases. Mol Cell Biochem 480(7):4379\u20134399","journal-title":"Mol Cell Biochem"},{"issue":"4","key":"2375_CR30","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1177\/03009858211005537","volume":"58","author":"SF Santagostino","year":"2021","unstructured":"Santagostino SF, Assenmacher CA, Tarrant JC, Adedeji AO, Radaelli E (2021) Mechanisms of regulated cell death: current perspectives. Vet Pathol 58(4):596\u2013623","journal-title":"Vet Pathol"},{"issue":"8","key":"2375_CR31","doi-asserted-by":"publisher","first-page":"2020","DOI":"10.1002\/1878-0261.13625","volume":"18","author":"A Valles-Marti","year":"2024","unstructured":"Valles-Marti A, de Goeij-de Haas RR, Henneman AA, Piersma SR, Pham TV, Knol JC et al (2024) Kinase activities in pancreatic ductal adenocarcinoma with prognostic and therapeutic avenues. Mol Oncol 18(8):2020\u20132041","journal-title":"Mol Oncol"},{"issue":"1","key":"2375_CR32","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1007\/s11033-025-11284-7","volume":"53","author":"E Alabas","year":"2025","unstructured":"Alabas E, Ozcimen AA (2025) The integrin-matrix-FAK-EMT axis in Anoikis resistance: a critical network in tumor progression and therapy. Mol Biol Rep 53(1):108","journal-title":"Mol Biol Rep"},{"issue":"10","key":"2375_CR33","doi-asserted-by":"publisher","first-page":"2640","DOI":"10.1111\/cas.70154","volume":"116","author":"B Liu","year":"2025","unstructured":"Liu B, Wu Q, Xuan Z, Zheng Z, Du Y, Sui X et al (2025) Mechanisms involved in focal adhesion signaling regulating tumor anoikis resistance. Cancer Sci 116(10):2640\u20132648","journal-title":"Cancer Sci"},{"issue":"10","key":"2375_CR34","doi-asserted-by":"publisher","first-page":"872","DOI":"10.1038\/s41419-021-04133-5","volume":"12","author":"TR Rutherford","year":"2021","unstructured":"Rutherford TR, Elder AM, Lyons TR (2021) Anoikis resistance in mammary epithelial cells is mediated by semaphorin 7a. Cell Death Dis 12(10):872","journal-title":"Cell Death Dis"},{"issue":"1","key":"2375_CR35","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1158\/1535-7163.MCT-17-1261","volume":"18","author":"SD da Silva","year":"2019","unstructured":"da Silva SD, Xu B, Maschietto M, Marchi FA, Alkailani MI, Bijian K et al (2019) TRAF2 cooperates with focal adhesion signaling to regulate cancer cell susceptibility to anoikis. Mol Cancer Ther 18(1):139\u2013146","journal-title":"Mol Cancer Ther"},{"issue":"43","key":"2375_CR36","doi-asserted-by":"publisher","first-page":"70336","DOI":"10.18632\/oncotarget.11856","volume":"7","author":"S Walker","year":"2016","unstructured":"Walker S, Foster F, Wood A, Owens T, Brennan K, Streuli CH et al (2016) Oncogenic activation of FAK drives apoptosis suppression in a 3D-culture model of breast cancer initiation. Oncotarget 7(43):70336\u201370352","journal-title":"Oncotarget"},{"issue":"11","key":"2375_CR37","doi-asserted-by":"publisher","first-page":"392","DOI":"10.31083\/j.fbl2911392","volume":"29","author":"K Katoh","year":"2024","unstructured":"Katoh K (2024) Signal transduction mechanisms of focal adhesions: Src and FAK-mediated cell response. Front Biosci Landmark Ed 29(11):392","journal-title":"Front Biosci (Landmark Ed)"},{"issue":"1","key":"2375_CR38","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1080\/27694127.2022.2047266","volume":"1","author":"M Zhao","year":"2022","unstructured":"Zhao M, Finlay D, Liddington R, Vuori K (2022) SRC plays a specific role in the cross-talk between apoptosis and autophagy via phosphorylation of a novel regulatory site on AMPK. Autophagy Rep 1(1):38\u201341","journal-title":"Autophagy Rep"},{"issue":"9","key":"2375_CR39","doi-asserted-by":"publisher","first-page":"1116","DOI":"10.1007\/s10495-017-1392-0","volume":"22","author":"AP de Sousa Mesquita","year":"2017","unstructured":"de Sousa Mesquita AP, de Araujo Lopes S, Pernambuco Filho PCA, Nader HB, Lopes CC (2017) Acquisition of anoikis resistance promotes alterations in the Ras\/ERK and PI3K\/Akt signaling pathways and matrix remodeling in endothelial cells. Apoptosis 22(9):1116\u20131137","journal-title":"Apoptosis"},{"issue":"1","key":"2375_CR40","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/s12943-015-0482-2","volume":"15","author":"BC Luey","year":"2016","unstructured":"Luey BC, May FE (2016) Insulin-like growth factors are essential to prevent anoikis in oestrogen-responsive breast cancer cells: importance of the type I IGF receptor and PI3-kinase\/Akt pathway. Mol Cancer 15(1):8","journal-title":"Mol Cancer"},{"issue":"8","key":"2375_CR41","doi-asserted-by":"publisher","first-page":"1271","DOI":"10.1038\/cdd.2016.15","volume":"23","author":"JA Mason","year":"2016","unstructured":"Mason JA, Davison-Versagli CA, Leliaert AK, Pape DJ, McCallister C, Zuo J et al (2016) Oncogenic Ras differentially regulates metabolism and anoikis in extracellular matrix-detached cells. Cell Death Differ 23(8):1271\u20131282","journal-title":"Cell Death Differ"},{"issue":"6","key":"2375_CR42","doi-asserted-by":"publisher","first-page":"1497","DOI":"10.1158\/0008-5472.CAN-17-2090","volume":"78","author":"M Saha","year":"2018","unstructured":"Saha M, Kumar S, Bukhari S, Balaji SA, Kumar P, Hindupur SK et al (2018) AMPK-Akt double-negative feedback loop in breast cancer cells regulates their adaptation to matrix deprivation. Cancer Res 78(6):1497\u20131510","journal-title":"Cancer Res"},{"key":"2375_CR43","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1242\/jcs.212563","volume":"131","author":"CRL Oudenaarden","year":"2018","unstructured":"Oudenaarden CRL, van de Ven RAH, Derksen PWB (2018) Re-inforcing the cell death army in the fight against breast cancer. J Cell Sci 131:16","journal-title":"J Cell Sci"},{"issue":"2","key":"2375_CR44","doi-asserted-by":"publisher","first-page":"581","DOI":"10.7314\/APJCP.2016.17.2.581","volume":"17","author":"C Akekawatchai","year":"2016","unstructured":"Akekawatchai C, Roytrakul S, Kittisenachai S, Isarankura-Na-Ayudhya P, Jitrapakdee S (2016) Protein profiles associated with anoikis resistance of metastatic MDA-MB-231 breast cancer cells. Asian Pac J Cancer Prev 17(2):581\u2013590","journal-title":"Asian Pac J Cancer Prev"},{"issue":"4","key":"2375_CR45","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1093\/jb\/mvy047","volume":"164","author":"M Saitoh","year":"2018","unstructured":"Saitoh M (2018) Involvement of partial EMT in cancer progression. J Biochem 164(4):257\u2013264","journal-title":"J Biochem"},{"issue":"12","key":"2375_CR46","doi-asserted-by":"publisher","first-page":"3674","DOI":"10.3390\/cancers12123674","volume":"12","author":"R Hass","year":"2020","unstructured":"Hass R, von der Ohe J, Ungefroren H (2020) The intimate relationship among EMT, MET and TME: AT (ransdifferentiation) E (nhancing) M (ix) to be exploited for therapeutic purposes. Cancers 12(12):3674","journal-title":"Cancers"},{"issue":"1","key":"2375_CR47","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1186\/s12943-023-01744-8","volume":"22","author":"Z Yuan","year":"2023","unstructured":"Yuan Z, Li Y, Zhang S, Wang X, Dou H, Yu X et al (2023) Extracellular matrix remodeling in tumor progression and immune escape: from mechanisms to treatments. Mol Cancer 22(1):48","journal-title":"Mol Cancer"},{"key":"2375_CR48","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.canlet.2021.03.011","volume":"508","author":"HJ Han","year":"2021","unstructured":"Han HJ, Sung JY, Kim SH, Yun UJ, Kim H, Jang EJ et al (2021) Fibronectin regulates anoikis resistance via cell aggregate formation. Cancer Lett 508:59\u201372","journal-title":"Cancer Lett"},{"key":"2375_CR49","doi-asserted-by":"publisher","first-page":"780176","DOI":"10.3389\/fcell.2022.780176","volume":"10","author":"MR Shait Mohammed","year":"2022","unstructured":"Shait Mohammed MR, Zamzami M, Choudhry H, Ahmed F, Ateeq B, Khan MI (2022) The histone H3K27me3 demethylases KDM6A\/B resist anoikis and transcriptionally regulate stemness-related genes. Front Cell Dev Biol 10:780176","journal-title":"Front Cell Dev Biol"},{"key":"2375_CR50","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.semcancer.2021.03.008","volume":"82","author":"R Zhang","year":"2022","unstructured":"Zhang R, Tu J, Liu S (2022) Novel molecular regulators of breast cancer stem cell plasticity and heterogeneity. Semin Cancer Biol 82:11\u201325","journal-title":"Semin Cancer Biol"},{"key":"2375_CR51","doi-asserted-by":"publisher","first-page":"626577","DOI":"10.3389\/fonc.2021.626577","volume":"11","author":"FO Adeshakin","year":"2021","unstructured":"Adeshakin FO, Adeshakin AO, Afolabi LO, Yan D, Zhang G, Wan X (2021) Mechanisms for modulating anoikis resistance in cancer and the relevance of metabolic reprogramming. Front Oncol 11:626577","journal-title":"Front Oncol"},{"key":"2375_CR52","doi-asserted-by":"publisher","first-page":"1422281","DOI":"10.3389\/fphar.2024.1422281","volume":"15","author":"S Peppicelli","year":"2024","unstructured":"Peppicelli S, Kersikla T, Menegazzi G, Andreucci E, Ruzzolini J, Nediani C et al (2024) The critical role of glutamine and fatty acids in the metabolic reprogramming of anoikis-resistant melanoma cells. Front Pharmacol 15:1422281","journal-title":"Front Pharmacol"},{"issue":"11","key":"2375_CR53","doi-asserted-by":"publisher","first-page":"1717","DOI":"10.1002\/cbin.11896","volume":"46","author":"M Raeisi","year":"2022","unstructured":"Raeisi M, Zehtabi M, Velaei K, Fayyazpour P, Aghaei N, Mehdizadeh A (2022) Anoikis in cancer: the role of lipid signaling. Cell Biol Int 46(11):1717\u20131728","journal-title":"Cell Biol Int"},{"issue":"1","key":"2375_CR54","doi-asserted-by":"publisher","first-page":"4867","DOI":"10.1038\/s41467-021-25189-z","volume":"12","author":"R Taftaf","year":"2021","unstructured":"Taftaf R, Liu X, Singh S, Jia Y, Dashzeveg NK, Hoffmann AD et al (2021) ICAM1 initiates CTC cluster formation and trans-endothelial migration in lung metastasis of breast cancer. Nat Commun 12(1):4867","journal-title":"Nat Commun"},{"key":"2375_CR55","doi-asserted-by":"crossref","unstructured":"Guan C, Hao L, Gong B, Zheng L (2025) CTC cluster in breast cancer: synergetic metastasis promotion mechanism and transformation path from platelet cloaking to leukocyte escort. Clin Transl Oncol, 1-12.","DOI":"10.1007\/s12094-025-04150-2"},{"issue":"1","key":"2375_CR56","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1007\/s10549-021-06299-0","volume":"189","author":"U Sharma","year":"2021","unstructured":"Sharma U, Medina-Saenz K, Miller PC, Troness B, Spartz A, Sandoval-Leon A et al (2021) Heterotypic clustering of circulating tumor cells and circulating cancer-associated fibroblasts facilitates breast cancer metastasis. Breast Cancer Res Treat 189(1):63\u201380","journal-title":"Breast Cancer Res Treat"},{"issue":"2","key":"2375_CR57","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1016\/j.taap.2015.09.011","volume":"289","author":"IH Chen","year":"2015","unstructured":"Chen IH, Shih HC, Hsieh PW, Chang FR, Wu YC, Wu CC (2015) HPW-RX40 restores anoikis sensitivity of human breast cancer cells by inhibiting integrin\/FAK signaling. Toxicol Appl Pharmacol 289(2):330\u2013340","journal-title":"Toxicol Appl Pharmacol"},{"issue":"9","key":"2375_CR58","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1038\/s41389-018-0083-1","volume":"7","author":"S Tiede","year":"2018","unstructured":"Tiede S, Meyer-Schaller N, Kalathur RKR, Ivanek R, Fagiani E, Schmassmann P et al (2018) The FAK inhibitor BI 853520 exerts anti-tumor effects in breast cancer. Oncogenesis 7(9):73","journal-title":"Oncogenesis"},{"issue":"9","key":"2375_CR59","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1038\/nrc3792","volume":"14","author":"FJ Sulzmaier","year":"2014","unstructured":"Sulzmaier FJ, Jean C, Schlaepfer DD (2014) FAK in cancer: mechanistic findings and clinical applications. Nat Rev Cancer 14(9):598\u2013610","journal-title":"Nat Rev Cancer"},{"issue":"4","key":"2375_CR60","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1080\/13543784.2020.1740680","volume":"29","author":"A Mohanty","year":"2020","unstructured":"Mohanty A, Pharaon RR, Nam A, Salgia S, Kulkarni P, Massarelli E (2020) FAK-targeted and combination therapies for the treatment of cancer: an overview of phase I and II clinical trials. Expert Opin Investig Drugs 29(4):399\u2013409","journal-title":"Expert Opin Investig Drugs"},{"issue":"1","key":"2375_CR61","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1134\/S0006297915010113","volume":"80","author":"GE Morozevich","year":"2015","unstructured":"Morozevich GE, Kozlova NI, Susova OY, Karalkin PA, Berman AE (2015) Implication of alpha2beta1 integrin in anoikis of MCF-7 human breast carcinoma cells. Biochemistry 80(1):97\u2013103","journal-title":"Biochem (Mosc)"},{"issue":"1","key":"2375_CR62","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1186\/s12885-017-3953-6","volume":"18","author":"CJ Lovitt","year":"2018","unstructured":"Lovitt CJ, Shelper TB, Avery VM (2018) Doxorubicin resistance in breast cancer cells is mediated by extracellular matrix proteins. BMC Cancer 18(1):41","journal-title":"BMC Cancer"},{"issue":"3","key":"2375_CR63","doi-asserted-by":"publisher","first-page":"zcab027","DOI":"10.1093\/narcan\/zcab027","volume":"3","author":"S Sahoo","year":"2021","unstructured":"Sahoo S, Mishra A, Kaur H, Hari K, Muralidharan S, Mandal S et al (2021) A mechanistic model captures the emergence and implications of non-genetic heterogeneity and reversible drug resistance in ER+ breast cancer cells. NAR Cancer 3(3):zcab027","journal-title":"NAR Cancer"},{"issue":"11","key":"2375_CR64","doi-asserted-by":"publisher","first-page":"130215","DOI":"10.1016\/j.bbagen.2022.130215","volume":"1866","author":"P Kundu","year":"2022","unstructured":"Kundu P, Shankar BS (2022) Macrophage induced ERK-TGF-beta1 signaling in MCF7 breast cancer cells result in reversible cancer stem cell plasticity and epithelial mesenchymal transition. Biochim Biophys Acta BBA Gen Subj 1866(11):130215","journal-title":"Biochim Biophys Acta Gen Subj"},{"issue":"4","key":"2375_CR65","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1007\/s10555-016-9648-7","volume":"35","author":"CL Chaffer","year":"2016","unstructured":"Chaffer CL, San Juan BP, Lim E, Weinberg RA (2016) EMT, cell plasticity and metastasis. Cancer Metastasis Rev 35(4):645\u2013654","journal-title":"Cancer Metastasis Rev"},{"issue":"26","key":"2375_CR66","doi-asserted-by":"publisher","first-page":"e2304374","DOI":"10.1002\/adhm.202304374","volume":"13","author":"B Schnoor","year":"2024","unstructured":"Schnoor B, Morris K, Kottana RK, Muldoon R, Barron J, Papa AL (2024) Fibrinolytic platelet decoys reduce cancer metastasis by dissociating circulating tumor cell clusters. Adv Healthc Mater 13(26):e2304374","journal-title":"Adv Healthc Mater"},{"issue":"21","key":"2375_CR67","doi-asserted-by":"publisher","first-page":"4474","DOI":"10.1158\/0008-5472.CAN-15-0684","volume":"75","author":"JW Choi","year":"2015","unstructured":"Choi JW, Kim JK, Yang YJ, Kim P, Yoon KH, Yun SH (2015) Urokinase exerts antimetastatic effects by dissociating clusters of circulating tumor cells. Cancer Res 75(21):4474\u20134482","journal-title":"Cancer Res"},{"issue":"8","key":"2375_CR68","doi-asserted-by":"publisher","first-page":"1326","DOI":"10.1038\/aps.2017.189","volume":"39","author":"RR Wei","year":"2018","unstructured":"Wei RR, Sun DN, Yang H, Yan J, Zhang X, Zheng XL et al (2018) CTC clusters induced by heparanase enhance breast cancer metastasis. Acta Pharmacol Sin 39(8):1326\u20131337","journal-title":"Acta Pharmacol Sin"},{"key":"2375_CR69","doi-asserted-by":"crossref","unstructured":"Li D, Park Y, Hemati H, Liu X (2023) Cell aggregation prevents anoikis and induces CD44 cleavage by maintaining lipid raft integrity to promote triple negative breast cancer metastasis. Springer Science and Business Media LLC","DOI":"10.21203\/rs.3.rs-2535728\/v1"},{"issue":"4","key":"2375_CR70","doi-asserted-by":"publisher","first-page":"3730","DOI":"10.1002\/jcp.27149","volume":"234","author":"S Li","year":"2019","unstructured":"Li S, Chen Y, Zhang Y, Jiang X, Jiang Y, Qin X et al (2019) Shear stress promotes anoikis resistance of cancer cells via caveolin-1-dependent extrinsic and intrinsic apoptotic pathways. J Cell Physiol 234(4):3730\u20133743","journal-title":"J Cell Physiol"},{"key":"2375_CR71","doi-asserted-by":"publisher","first-page":"107327482110663","DOI":"10.1177\/10732748211066311","volume":"28","author":"X Meng","year":"2021","unstructured":"Meng X, Dang T, Chai J (2021) From apoptosis to necroptosis: the death wishes to cancer. Cancer Control 28:10732748211066311","journal-title":"Cancer Control"},{"key":"2375_CR72","doi-asserted-by":"publisher","first-page":"1446486","DOI":"10.3389\/fphar.2024.1446486","volume":"15","author":"S Wang","year":"2024","unstructured":"Wang S, He H, Qu L, Shen Q, Dai Y (2024) Dual roles of inflammatory programmed cell death in cancer: insights into pyroptosis and necroptosis. Front Pharmacol 15:1446486","journal-title":"Front Pharmacol"},{"issue":"3","key":"2375_CR73","doi-asserted-by":"publisher","first-page":"941","DOI":"10.1007\/s10555-024-10178-7","volume":"43","author":"S Zhou","year":"2024","unstructured":"Zhou S, Xu H, Duan Y, Tang Q, Huang H, Bi F (2024) Survival mechanisms of circulating tumor cells and their implications for cancer treatment. Cancer Metastasis Rev 43(3):941\u2013957","journal-title":"Cancer Metastasis Rev"},{"issue":"9Supplement","key":"2375_CR74","first-page":"PO4","volume":"84","author":"T Ojo","year":"2024","unstructured":"Ojo T, Ranganathan S (2024) Abstract PO4-06-10: Targeting necroptosis in breast cancer induced by Ophiobolin A. Cancer Res 84(9Supplement):PO4\u201306","journal-title":"Cancer Res"},{"issue":"23","key":"2375_CR75","doi-asserted-by":"publisher","first-page":"7199","DOI":"10.1007\/s00018-021-03947-y","volume":"78","author":"S Liu","year":"2021","unstructured":"Liu S, Joshi K, Denning MF, Zhang J (2021) RIPK3 signaling and its role in the pathogenesis of cancers. Cell Mol Life Sci 78(23):7199\u20137217","journal-title":"Cell Mol Life Sci"},{"issue":"9","key":"2375_CR76","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1007\/s10495-020-01632-2","volume":"25","author":"C Wu","year":"2020","unstructured":"Wu C, Zhou L, Yuan H, Wu S (2020) Interconnections among major forms of regulated cell death. Apoptosis 25(9):616\u2013624","journal-title":"Apoptosis"},{"issue":"3","key":"2375_CR77","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/j.tips.2016.12.005","volume":"38","author":"KW Wegner","year":"2017","unstructured":"Wegner KW, Saleh D, Degterev A (2017) Complex pathologic roles of RIPK1 and RIPK3: moving beyond necroptosis. Trends Pharmacol Sci 38(3):202\u2013225","journal-title":"Trends Pharmacol Sci"},{"issue":"1","key":"2375_CR78","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1186\/s12943-019-1029-8","volume":"18","author":"Y Gong","year":"2019","unstructured":"Gong Y, Fan Z, Luo G, Yang C, Huang Q, Fan K et al (2019) The role of necroptosis in cancer biology and therapy. Mol Cancer 18(1):100","journal-title":"Mol Cancer"},{"key":"2375_CR79","doi-asserted-by":"publisher","first-page":"1480027","DOI":"10.3389\/fimmu.2025.1480027","volume":"16","author":"K Yao","year":"2025","unstructured":"Yao K, Shi Z, Zhao F, Tan C, Zhang Y, Fan H et al (2025) RIPK1 in necroptosis and recent progress in related pharmaceutics. Front Immunol 16:1480027","journal-title":"Front Immunol"},{"issue":"16","key":"2375_CR80","doi-asserted-by":"publisher","first-page":"2048","DOI":"10.3390\/cells12162048","volume":"12","author":"I Fiorilla","year":"2023","unstructured":"Fiorilla I, Martinotti S, Todesco AM, Bonsignore G, Cavaletto M, Patrone M et al (2023) Chronic inflammation, oxidative stress and metabolic plasticity: three players driving the pro-tumorigenic microenvironment in malignant mesothelioma. Cells 12(16):2048","journal-title":"Cells"},{"issue":"8","key":"2375_CR81","doi-asserted-by":"publisher","first-page":"1376","DOI":"10.1038\/cdd.2011.10","volume":"18","author":"M Darding","year":"2011","unstructured":"Darding M, Feltham R, Tenev T, Bianchi K, Benetatos C, Silke J et al (2011) Molecular determinants of Smac mimetic induced degradation of cIAP1 and cIAP2. Cell Death Differ 18(8):1376\u20131386","journal-title":"Cell Death Differ"},{"key":"2375_CR82","doi-asserted-by":"publisher","first-page":"656908","DOI":"10.3389\/fimmu.2021.656908","volume":"12","author":"D Laha","year":"2021","unstructured":"Laha D, Grant R, Mishra P, Nilubol N (2021) The role of tumor necrosis factor in manipulating the immunological response of tumor microenvironment. Front Immunol 12:656908","journal-title":"Front Immunol"},{"key":"2375_CR83","doi-asserted-by":"crossref","unstructured":"(2021) Corrigendum: Breast cancer immunology and immunotherapy: targeting the programmed cell death protein-1\/programmed cell death protein ligand-1. Chin Med J 134(6):756","DOI":"10.1097\/CM9.0000000000001392"},{"key":"2375_CR84","doi-asserted-by":"publisher","first-page":"1701031","DOI":"10.3389\/fonc.2025.1701031","volume":"15","author":"S Sarkar","year":"2025","unstructured":"Sarkar S (2025) Sleepyhead, deadly awakening: the dynamics of metastatic organotropism, tumor dormancy and therapeutic implications. Front Oncol 15:1701031","journal-title":"Front Oncol"},{"issue":"20","key":"2375_CR85","doi-asserted-by":"publisher","first-page":"9902","DOI":"10.3390\/ijms26209902","volume":"26","author":"A Szulc","year":"2025","unstructured":"Szulc A, Wozniak M (2025) Targeting ferroptosis as the Achilles\u2019 heel of breast cancer: mechanisms and therapeutic opportunities from a comprehensive systematic review. Int J Mol Sci 26(20):9902","journal-title":"Int J Mol Sci"},{"issue":"10","key":"2375_CR86","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1631\/jzus.B2200194","volume":"23","author":"L Qu","year":"2022","unstructured":"Qu L, He X, Tang Q, Fan X, Liu J, Lin A (2022) Iron metabolism, ferroptosis, and lncRNA in cancer: knowns and unknowns. J Zhejiang Univ Sci B 23(10):844\u2013862","journal-title":"J Zhejiang Univ Sci B"},{"key":"2375_CR87","doi-asserted-by":"publisher","first-page":"1499125","DOI":"10.3389\/fonc.2024.1499125","volume":"14","author":"C Peng","year":"2024","unstructured":"Peng C, Chen Y, Jiang M (2024) Targeting ferroptosis: a promising strategy to overcome drug resistance in breast cancer. Front Oncol 14:1499125","journal-title":"Front Oncol"},{"issue":"5","key":"2375_CR88","first-page":"2079","volume":"21","author":"SE Antmen","year":"2025","unstructured":"Antmen SE, Yalaza C, Tuncel F, Berkesoglu M, Erturk SE, Canacankatan N (2025) Triple-negative breast cancer and ferroptosis: expression profiling of key regulatory genes. Arch Med Sci 21(5):2079\u20132087","journal-title":"Arch Med Sci"},{"issue":"1","key":"2375_CR89","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1186\/s12943-025-02520-6","volume":"24","author":"Y Wu","year":"2025","unstructured":"Wu Y, Li H, Yue K, Jing C, Duan Y (2025) Ferroptosis in cancer: metabolism, mechanisms and therapeutic prospects. Mol Cancer 24(1):303","journal-title":"Mol Cancer"},{"issue":"3","key":"2375_CR90","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1158\/2159-8290.CD-21-0922","volume":"12","author":"R Pillai","year":"2022","unstructured":"Pillai R, Hayashi M, Zavitsanou AM, Papagiannakopoulos T (2022) NRF2: KEAPing tumors protected. Cancer Discov 12(3):625\u2013643","journal-title":"Cancer Discov"},{"key":"2375_CR91","first-page":"47","volume":"7","author":"Y Wang","year":"2024","unstructured":"Wang Y, Yu G, Chen X (2024) Mechanism of ferroptosis resistance in cancer cells. Cancer Drug Resist 7:47","journal-title":"Cancer Drug Resist"},{"key":"2375_CR92","first-page":"1690","volume":"24","author":"M Rafeeq","year":"2025","unstructured":"Rafeeq M, Afzal M, Nadeem MS, Habib AH, Alsufyani HA, Alzarea SI et al (2025) Targeting TNFR1-driven necroptosis in breast cancer. EXCLI J 24:1690","journal-title":"EXCLI J"},{"key":"2375_CR93","doi-asserted-by":"publisher","first-page":"595722","DOI":"10.3389\/fimmu.2021.595722","volume":"12","author":"J-F Rossi","year":"2021","unstructured":"Rossi J-F, Lu ZY, Massart C, Levon K (2021) Dynamic immune\/inflammation precision medicine: the good and the bad inflammation in infection and cancer. Front Immunol 12:595722","journal-title":"Front Immunol"},{"issue":"1","key":"2375_CR94","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1159\/000334245","volume":"4","author":"G Nace","year":"2011","unstructured":"Nace G, Evankovich J, Eid R, Tsung A (2011) Dendritic cells and damage-associated molecular patterns: endogenous danger signals linking innate and adaptive immunity. J Innate Immun 4(1):6\u201315","journal-title":"J Innate Immun"},{"issue":"3","key":"2375_CR95","doi-asserted-by":"publisher","first-page":"e004031","DOI":"10.1136\/jitc-2021-004031","volume":"10","author":"L Nicole","year":"2022","unstructured":"Nicole L, Sanavia T, Cappellesso R, Maffeis V, Akiba J, Kawahara A et al (2022) Necroptosis-driving genes RIPK1, RIPK3 and MLKL-p are associated with intratumoral CD3(+) and CD8(+) T cell density and predict prognosis in hepatocellular carcinoma. J Immunother Cancer 10(3):e004031","journal-title":"J Immunother Cancer"},{"issue":"8","key":"2375_CR96","doi-asserted-by":"publisher","first-page":"e13644","DOI":"10.1111\/cpr.13644","volume":"57","author":"L Yu","year":"2024","unstructured":"Yu L, Huang K, Liao Y, Wang L, Sethi G, Ma Z (2024) Targeting novel regulated cell death: ferroptosis, pyroptosis and necroptosis in anti-PD-1\/PD-L1 cancer immunotherapy. Cell Prolif 57(8):e13644","journal-title":"Cell Prolif"},{"key":"2375_CR97","doi-asserted-by":"publisher","first-page":"483","DOI":"10.3389\/fimmu.2013.00483","volume":"4","author":"G Schiavoni","year":"2013","unstructured":"Schiavoni G, Mattei F, Gabriele L (2013) Type I interferons as stimulators of DC-mediated cross-priming: impact on anti-tumor response. Front Immunol 4:483","journal-title":"Front Immunol"},{"key":"2375_CR98","doi-asserted-by":"publisher","first-page":"954992","DOI":"10.3389\/fimmu.2022.954992","volume":"13","author":"MT Bilotta","year":"2022","unstructured":"Bilotta MT, Antignani A, Fitzgerald DJ (2022) Managing the TME to improve the efficacy of cancer therapy. Front Immunol 13:954992","journal-title":"Front Immunol"},{"issue":"15","key":"2375_CR99","doi-asserted-by":"publisher","first-page":"3918","DOI":"10.3390\/cancers13153918","volume":"13","author":"DN Danforth","year":"2021","unstructured":"Danforth DN (2021) The role of chronic inflammation in the development of breast cancer. Cancers 13(15):3918","journal-title":"Cancers"},{"issue":"5","key":"2375_CR100","first-page":"625","volume":"22","author":"H Liu","year":"2020","unstructured":"Liu H, Sun Y, O\u2019Brien JA, Franco-Barraza J, Qi X, Yuan H et al (2020) Necroptotic astrocytes contribute to maintaining stemness of disseminated medulloblastoma through CCL2 secretion. Neurooncology 22(5):625\u2013638","journal-title":"Neurooncology"},{"issue":"1","key":"2375_CR101","doi-asserted-by":"publisher","first-page":"217","DOI":"10.3390\/cells9010217","volume":"9","author":"W Jin","year":"2020","unstructured":"Jin W (2020) Role of JAK\/STAT3 signaling in the regulation of metastasis, the transition of cancer stem cells, and chemoresistance of cancer by epithelial\u2013mesenchymal transition. Cells 9(1):217","journal-title":"Cells"},{"issue":"9","key":"2375_CR102","doi-asserted-by":"publisher","first-page":"2053","DOI":"10.3390\/cancers13092053","volume":"13","author":"CM Neophytou","year":"2021","unstructured":"Neophytou CM, Panagi M, Stylianopoulos T, Papageorgis P (2021) The role of tumor microenvironment in cancer metastasis: molecular mechanisms and therapeutic opportunities. Cancers 13(9):2053","journal-title":"Cancers"},{"issue":"7","key":"2375_CR103","doi-asserted-by":"publisher","first-page":"2100029","DOI":"10.1002\/bies.202100029","volume":"43","author":"PP Yee","year":"2021","unstructured":"Yee PP, Li W (2021) Tumor necrosis: a synergistic consequence of metabolic stress and inflammation. BioEssays 43(7):2100029","journal-title":"BioEssays"},{"issue":"1","key":"2375_CR104","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1038\/s41392-022-01046-3","volume":"7","author":"W Gao","year":"2022","unstructured":"Gao W, Wang X, Zhou Y, Wang X, Yu Y (2022) Autophagy, ferroptosis, pyroptosis, and necroptosis in tumor immunotherapy. Signal Transduct Target Ther 7(1):196","journal-title":"Signal Transduct Target therapy"},{"key":"2375_CR105","doi-asserted-by":"publisher","first-page":"1026954","DOI":"10.3389\/fimmu.2022.1026954","volume":"13","author":"C Kerneur","year":"2022","unstructured":"Kerneur C, Cano CE, Olive D (2022) Major pathways involved in macrophage polarization in cancer. Front Immunol 13:1026954","journal-title":"Front Immunol"},{"issue":"2","key":"2375_CR106","doi-asserted-by":"publisher","first-page":"875","DOI":"10.3390\/ijms27020875","volume":"27","author":"DJ Kim","year":"2026","unstructured":"Kim DJ (2026) Molecular and immune mechanisms governing cancer metastasis, including dormancy, microenvironmental niches, and tumor-specific programs. Int J Mol Sci 27(2):875","journal-title":"Int J Mol Sci"},{"key":"2375_CR107","doi-asserted-by":"publisher","first-page":"835879","DOI":"10.3389\/fimmu.2022.835879","volume":"13","author":"T Ma","year":"2022","unstructured":"Ma T, Li X, Zhu Y, Yu S, Liu T, Zhang X et al (2022) Excessive activation of notch signaling in macrophages promote kidney inflammation, fibrosis, and necroptosis. Front Immunol 13:835879","journal-title":"Front Immunol"},{"issue":"1","key":"2375_CR108","doi-asserted-by":"publisher","first-page":"2795090","DOI":"10.1155\/2016\/2795090","volume":"2016","author":"H-Y Tan","year":"2016","unstructured":"Tan H-Y, Wang N, Li S, Hong M, Wang X, Feng Y (2016) The reactive oxygen species in macrophage polarization: reflecting its dual role in progression and treatment of human diseases. Oxidative Med Cell Longev 2016(1):2795090","journal-title":"Oxidative Med Cell Longev"},{"key":"2375_CR109","doi-asserted-by":"publisher","first-page":"888713","DOI":"10.3389\/fimmu.2022.888713","volume":"13","author":"J Gao","year":"2022","unstructured":"Gao J, Liang Y, Wang L (2022) Shaping polarization of tumor-associated macrophages in cancer immunotherapy. Front Immunol 13:888713","journal-title":"Front Immunol"},{"key":"2375_CR110","doi-asserted-by":"crossref","unstructured":"Saeed A (2025) Tumor-associated macrophage: polarization, immunoregulation and immunotherapy. MDPI AG","DOI":"10.20944\/preprints202504.0220.v1"},{"issue":"1","key":"2375_CR111","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1186\/s12935-021-02089-2","volume":"21","author":"J Liu","year":"2021","unstructured":"Liu J, Geng X, Hou J, Wu G (2021) New insights into M1\/M2 macrophages: key modulators in cancer progression. Cancer Cell Int 21(1):389","journal-title":"Cancer Cell Int"},{"issue":"1","key":"2375_CR112","first-page":"948098","volume":"2012","author":"N-B Hao","year":"2012","unstructured":"Hao N-B, L\u00fc M-H, Fan Y-H, Cao Y-L, Zhang Z-R, Yang S-M (2012) Macrophages in tumor microenvironments and the progression of tumors. J Immunol Res 2012(1):948098","journal-title":"J Immunol Res"},{"key":"2375_CR113","doi-asserted-by":"crossref","unstructured":"Ji, X., Huang, X., Li, C., Guan, N., Pan, T., Dong, J., & Li, L. (2023). Effect of tumor-associated macrophages on the pyroptosis of breast cancer tumor cells. Cell Communication and Signaling, 21(1), 197.","DOI":"10.1186\/s12964-023-01208-y"},{"issue":"1","key":"2375_CR114","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1038\/s41420-024-01958-9","volume":"10","author":"C Chen","year":"2024","unstructured":"Chen C, Liu J, Lin X, Xiang A, Ye Q, Guo J et al (2024) Crosstalk between cancer-associated fibroblasts and regulated cell death in tumors: insights into apoptosis, autophagy, ferroptosis, and pyroptosis. Cell Death Discov 10(1):189","journal-title":"Cell Death Discovery"},{"key":"2375_CR115","doi-asserted-by":"publisher","first-page":"1449696","DOI":"10.3389\/fonc.2024.1449696","volume":"14","author":"Y Ge","year":"2024","unstructured":"Ge Y, Jiang L, Yang C, Dong Q, Tang C, Xu Y et al (2024) Interactions between tumor-associated macrophages and regulated cell death: therapeutic implications in immuno-oncology. Front Oncol 14:1449696","journal-title":"Front Oncol"},{"issue":"1","key":"2375_CR116","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1042\/BST20160387","volume":"45","author":"B Erdogan","year":"2017","unstructured":"Erdogan B, Webb DJ (2017) Cancer-associated fibroblasts modulate growth factor signaling and extracellular matrix remodeling to regulate tumor metastasis. Biochem Soc Trans 45(1):229\u2013236","journal-title":"Biochem Soc Trans"},{"issue":"1","key":"2375_CR117","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1186\/s12935-024-03518-8","volume":"24","author":"S Yu","year":"2024","unstructured":"Yu S, Wang S, Wang X, Xu X (2024) The axis of tumor-associated macrophages, extracellular matrix proteins, and cancer-associated fibroblasts in oncogenesis. Cancer Cell Int 24(1):335","journal-title":"Cancer Cell Int"},{"issue":"2","key":"2375_CR118","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.tcb.2015.09.009","volume":"26","author":"SC Wei","year":"2016","unstructured":"Wei SC, Yang J (2016) Forcing through tumor metastasis: the interplay between tissue rigidity and epithelial\u2013mesenchymal transition. Trends Cell Biol 26(2):111\u2013120","journal-title":"Trends Cell Biol"},{"key":"2375_CR119","doi-asserted-by":"publisher","first-page":"1023177","DOI":"10.3389\/fonc.2022.1023177","volume":"12","author":"B Huang","year":"2022","unstructured":"Huang B, Lang X, Li X (2022) The role of IL-6\/JAK2\/STAT3 signaling pathway in cancers. Front Oncol 12:1023177","journal-title":"Front Oncol"},{"issue":"7","key":"2375_CR120","doi-asserted-by":"publisher","first-page":"848","DOI":"10.1593\/neo.13706","volume":"15","author":"Q Chang","year":"2013","unstructured":"Chang Q, Bournazou E, Sansone P, Berishaj M, Gao SP, Daly L et al (2013) The IL-6\/JAK\/Stat3 feed-forward loop drives tumorigenesis and metastasis. Neoplasia 15(7):848\u2013IN45","journal-title":"Neoplasia"},{"key":"2375_CR121","doi-asserted-by":"publisher","first-page":"643310","DOI":"10.3389\/fimmu.2021.643310","volume":"12","author":"AG Bozward","year":"2021","unstructured":"Bozward AG, Warricker F, Oo YH, Khakoo SI (2021) Natural killer cells and regulatory T cells cross talk in hepatocellular carcinoma: exploring therapeutic options for the next decade. Front Immunol 12:643310","journal-title":"Front Immunol"},{"key":"2375_CR122","doi-asserted-by":"crossref","unstructured":"Wang H, Li F, Hao P, Mei Y (2026) The Cold Tumor to Hot Tumor transformation strategy for triple-negative breast cancer: from mechanism to clinical translation. Mol Cell Biochem 1\u201318","DOI":"10.1007\/s11010-025-05456-z"},{"issue":"19","key":"2375_CR123","doi-asserted-by":"publisher","first-page":"5064","DOI":"10.1158\/1078-0432.CCR-13-3271","volume":"20","author":"JM Taube","year":"2014","unstructured":"Taube JM, Klein A, Brahmer JR, Xu H, Pan X, Kim JH et al (2014) Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti\u2013PD-1 therapy. Clin Cancer Res 20(19):5064\u20135074","journal-title":"Clin Cancer Res"},{"issue":"2","key":"2375_CR124","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1038\/cmi.2013.59","volume":"11","author":"H Fang","year":"2014","unstructured":"Fang H, Ang B, Xu X, Huang X, Wu Y, Sun Y et al (2014) TLR4 is essential for dendritic cell activation and anti-tumor T-cell response enhancement by DAMPs released from chemically stressed cancer cells. Cell Mol Immunol 11(2):150\u2013159","journal-title":"Cell Mol Immunol"},{"key":"2375_CR125","doi-asserted-by":"publisher","first-page":"584626","DOI":"10.3389\/fimmu.2020.584626","volume":"11","author":"F Antonangeli","year":"2020","unstructured":"Antonangeli F, Natalini A, Garassino MC, Sica A, Santoni A, Di Rosa F (2020) Regulation of PD-L1 expression by NF-\u03baB in cancer. Front Immunol 11:584626","journal-title":"Front Immunol"},{"issue":"5","key":"2375_CR126","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1038\/s41568-024-00674-x","volume":"24","author":"P Meier","year":"2024","unstructured":"Meier P, Legrand AJ, Adam D, Silke J (2024) Immunogenic cell death in cancer: targeting necroptosis to induce antitumour immunity. Nat Rev Cancer 24(5):299\u2013315","journal-title":"Nat Rev Cancer"},{"issue":"35","key":"2375_CR127","doi-asserted-by":"publisher","first-page":"e09277","DOI":"10.1002\/advs.202509277","volume":"12","author":"L Xu","year":"2025","unstructured":"Xu L, Zhuang C (2025) Mixed lineage kinase domain-like protein (MLKL): from mechanisms to therapeutic opportunities. Adv Sci 12(35):e09277","journal-title":"Adv Sci"},{"issue":"1","key":"2375_CR128","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1186\/s13046-025-03301-1","volume":"44","author":"Y Cai","year":"2025","unstructured":"Cai Y, Xiao H, Xue S, Li P, Zhan Z, Lin J et al (2025) Integrative analysis of immunogenic PANoptosis and experimental validation of cinobufagin-induced activation to enhance glioma immunotherapy. J Exp Clin Cancer Res 44(1):35","journal-title":"J Experimental Clin Cancer Res"},{"issue":"14","key":"2375_CR129","doi-asserted-by":"publisher","first-page":"11634","DOI":"10.3390\/ijms241411634","volume":"24","author":"J Hata","year":"2023","unstructured":"Hata J, Harigane Y, Matsuoka K, Akaihata H, Yaginuma K, Meguro S et al (2023) Mechanism of androgen-independent stromal proliferation in benign prostatic hyperplasia. Int J Mol Sci 24(14):11634","journal-title":"Int J Mol Sci"},{"issue":"1","key":"2375_CR130","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1111\/imr.13281","volume":"321","author":"C Luri-Rey","year":"2024","unstructured":"Luri-Rey C, Gomis G, Glez-Vaz J, Manzanal A, Martinez Ria\u00f1o A, Rodriguez Ruiz ME et al (2024) Cytotoxicity as a form of immunogenic cell death leading to efficient tumor antigen cross-priming. Immunol Rev 321(1):143\u2013151","journal-title":"Immunol Rev"},{"issue":"1","key":"2375_CR131","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1186\/s13045-020-00946-7","volume":"13","author":"R Tang","year":"2020","unstructured":"Tang R, Xu J, Zhang B, Liu J, Liang C, Hua J et al (2020) Ferroptosis, necroptosis, and pyroptosis in anticancer immunity. J Hematol Oncol 13(1):110","journal-title":"J Hematol Oncol"},{"key":"2375_CR132","doi-asserted-by":"publisher","first-page":"1274654","DOI":"10.3389\/fimmu.2023.1274654","volume":"14","author":"D Ke","year":"2023","unstructured":"Ke D, Zhang Z, Liu J, Chen P, Dai Y, Sun X et al (2023) RIPK1 and RIPK3 inhibitors: potential weapons against inflammation to treat diabetic complications. Front Immunol 14:1274654","journal-title":"Front Immunol"},{"issue":"1","key":"2375_CR133","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1007\/s10495-023-01905-6","volume":"29","author":"Y Zhou","year":"2024","unstructured":"Zhou Y, Cai Z, Zhai Y, Yu J, He Q, He Y et al (2024) Necroptosis inhibitors: mechanisms of action and therapeutic potential. Apoptosis 29(1):22\u201344","journal-title":"Apoptosis"},{"issue":"10","key":"2375_CR134","doi-asserted-by":"publisher","first-page":"4759","DOI":"10.7150\/thno.54072","volume":"11","author":"C Zhan","year":"2021","unstructured":"Zhan C, Huang M, Yang X, Hou J (2021) MLKL: functions beyond serving as the executioner of necroptosis. Theranostics 11(10):4759","journal-title":"Theranostics"},{"issue":"4","key":"2375_CR135","doi-asserted-by":"publisher","first-page":"1200","DOI":"10.1158\/1078-0432.CCR-18-3683","volume":"27","author":"Y Tan","year":"2021","unstructured":"Tan Y, Sementino E, Cheung M, Peri S, Menges CW, Kukuyan A-M et al (2021) Somatic epigenetic silencing of RIPK3 inactivates necroptosis and contributes to chemoresistance in malignant mesothelioma. Clin Cancer Res 27(4):1200\u20131213","journal-title":"Clin Cancer Res"},{"issue":"11","key":"2375_CR136","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1038\/s41580-023-00623-w","volume":"24","author":"J Clucas","year":"2023","unstructured":"Clucas J, Meier P (2023) Roles of RIPK1 as a stress sentinel coordinating cell survival and immunogenic cell death. Nat Rev Mol Cell Biol 24(11):835\u2013852","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"25","key":"2375_CR137","doi-asserted-by":"publisher","first-page":"7906","DOI":"10.7150\/thno.38425","volume":"9","author":"S Lim","year":"2019","unstructured":"Lim S, Park J, Shim MK, Um W, Yoon HY, Ryu JH et al (2019) Recent advances and challenges of repurposing nanoparticle-based drug delivery systems to enhance cancer immunotherapy. Theranostics 9(25):7906","journal-title":"Theranostics"},{"key":"2375_CR138","doi-asserted-by":"publisher","first-page":"1344272","DOI":"10.3389\/fimmu.2024.1344272","volume":"15","author":"P Ouyang","year":"2024","unstructured":"Ouyang P, Wang L, Wu J, Tian Y, Chen C, Li D et al (2024) Overcoming cold tumors: a combination strategy of immune checkpoint inhibitors. Front Immunol 15:1344272","journal-title":"Front Immunol"},{"issue":"8","key":"2375_CR139","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1038\/nrd.2016.39","volume":"15","author":"JN Fullerton","year":"2016","unstructured":"Fullerton JN, Gilroy DW (2016) Resolution of inflammation: a new therapeutic frontier. Nat Rev Drug Discov 15(8):551\u2013567","journal-title":"Nat Rev Drug Discovery"},{"issue":"3","key":"2375_CR140","doi-asserted-by":"publisher","first-page":"1490","DOI":"10.3390\/ijms23031490","volume":"23","author":"D Markovi\u0107","year":"2022","unstructured":"Markovi\u0107 D, Maslovari\u0107 I, Djiki\u0107 D, \u010coki\u0107 VP (2022) Neutrophil death in myeloproliferative neoplasms: shedding more light on neutrophils as a pathogenic link to chronic inflammation. Int J Mol Sci 23(3):1490","journal-title":"Int J Mol Sci"},{"key":"2375_CR141","doi-asserted-by":"crossref","unstructured":"Hua, Y., Duan, N., Sun, C., Yang, F., Tian, M., Sun, Y., ... & Yin, Y. (2025). Targeting SLC7A11-mediated cysteine metabolism for the treatment of trastuzumab-resistant HER2-positive breast cancer. Elife, 14, RP103953.","DOI":"10.7554\/eLife.103953"},{"issue":"6","key":"2375_CR142","doi-asserted-by":"publisher","first-page":"3403","DOI":"10.1097\/MS9.0000000000003173","volume":"87","author":"EI Obeagu","year":"2025","unstructured":"Obeagu EI, Tanko MSM (2025) Iron metabolism in breast cancer: mechanisms and therapeutic implications: a narrative review. Annals Med Surg 87(6):3403\u20133409","journal-title":"Annals Med Surg"},{"issue":"22","key":"2375_CR143","doi-asserted-by":"publisher","first-page":"7038","DOI":"10.1111\/febs.16059","volume":"289","author":"J Liu","year":"2022","unstructured":"Liu J, Kang R, Tang D (2022) Signaling pathways and defense mechanisms of ferroptosis. FEBS J 289(22):7038\u20137050","journal-title":"FEBS J"},{"issue":"5","key":"2375_CR144","doi-asserted-by":"publisher","first-page":"1296","DOI":"10.3390\/pr13051296","volume":"13","author":"\u0130 Gulcin","year":"2025","unstructured":"Gulcin \u0130, Alwasel SH (2025) Fe3+\u2009reducing power as the most common assay for understanding the biological functions of antioxidants. Processes 13(5):1296","journal-title":"Processes"},{"key":"2375_CR145","doi-asserted-by":"crossref","unstructured":"Venkataramani V (2021) Iron homeostasis and metabolism: two sides of a coin. In: Ferroptosis: mechanism and diseases, pp 25\u201340","DOI":"10.1007\/978-3-030-62026-4_3"},{"issue":"1","key":"2375_CR146","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1038\/s41419-021-04490-1","volume":"13","author":"S Zhang","year":"2022","unstructured":"Zhang S, Xin W, Anderson GJ, Li R, Gao L, Chen S et al (2022) Double-edge sword roles of iron in driving energy production versus instigating ferroptosis. Cell Death Dis 13(1):40","journal-title":"Cell Death Dis"},{"issue":"5","key":"2375_CR147","doi-asserted-by":"publisher","first-page":"804","DOI":"10.3390\/cells12050804","volume":"12","author":"MS Mortensen","year":"2023","unstructured":"Mortensen MS, Ruiz J, Watts JL (2023) Polyunsaturated fatty acids drive lipid peroxidation during ferroptosis. Cells 12(5):804","journal-title":"Cells"},{"issue":"10","key":"2375_CR148","doi-asserted-by":"publisher","first-page":"2668","DOI":"10.3390\/biomedicines10102668","volume":"10","author":"S Ghareghomi","year":"2022","unstructured":"Ghareghomi S, Habibi-Rezaei M, Arese M, Saso L, Moosavi-Movahedi AA (2022) Nrf2 modulation in breast cancer. Biomedicines 10(10):2668","journal-title":"Biomedicines"},{"key":"2375_CR149","doi-asserted-by":"publisher","first-page":"1701249","DOI":"10.3389\/fonc.2025.1701249","volume":"15","author":"R Tunc","year":"2025","unstructured":"Tunc R, Ates I, Yilmaz B, Medoro A, Davinelli S, Suzen S et al (2025) Modulating Nrf2 to control lipid peroxidation and ferroptosis: implications for cancer management. Front Oncol 15:1701249","journal-title":"Front Oncol"},{"issue":"3","key":"2375_CR150","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1002\/med.21933","volume":"43","author":"SC Koeberle","year":"2023","unstructured":"Koeberle SC, Kipp AP, Stuppner H, Koeberle A (2023) Ferroptosis-modulating small molecules for targeting drug-resistant cancer: challenges and opportunities in manipulating redox signaling. Med Res Rev 43(3):614\u2013682","journal-title":"Med Res Rev"},{"issue":"7","key":"2375_CR151","doi-asserted-by":"publisher","first-page":"778","DOI":"10.3390\/antiox13070778","volume":"13","author":"X Gu","year":"2024","unstructured":"Gu X, Mu C, Zheng R, Zhang Z, Zhang Q, Liang T (2024) The cancer antioxidant regulation system in therapeutic resistance. Antioxidants 13(7):778","journal-title":"Antioxidants"},{"key":"2375_CR152","doi-asserted-by":"publisher","first-page":"1247268","DOI":"10.3389\/fimmu.2023.1247268","volume":"14","author":"Z Zheng","year":"2023","unstructured":"Zheng Z, Su J, Bao X, Wang H, Bian C, Zhao Q et al (2023) Mechanisms and applications of radiation-induced oxidative stress in regulating cancer immunotherapy. Front Immunol 14:1247268","journal-title":"Front Immunol"},{"issue":"1","key":"2375_CR153","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1038\/s41419-025-07354-0","volume":"16","author":"J Cao","year":"2025","unstructured":"Cao J, Zhou T, Wu T, Lin R, Huang J, Shi D et al (2025) Targeting estrogen-regulated system xc\u2212 promotes ferroptosis and endocrine sensitivity of ER+ breast cancer. Cell Death Dis 16(1):30","journal-title":"Cell Death Dis"},{"issue":"1","key":"2375_CR154","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1038\/s42003-025-07513-1","volume":"8","author":"J Cao","year":"2025","unstructured":"Cao J, Wu T, Zhou T, Jiang Z, Ren Y, Yu J et al (2025) USP35 promotes the growth of ER positive breast cancer by inhibiting ferroptosis via BRD4-SLC7A11 axis. Commun Biol 8(1):64","journal-title":"Commun Biol"},{"issue":"12","key":"2375_CR155","doi-asserted-by":"publisher","first-page":"5521","DOI":"10.3390\/ijms26125521","volume":"26","author":"S Jannati","year":"2025","unstructured":"Jannati S, Patel A, Patnaik R, Banerjee Y (2025) Oleocanthal as a multifunctional anti-cancer agent: mechanistic insights, advanced delivery strategies, and synergies for precision oncology. Int J Mol Sci 26(12):5521","journal-title":"Int J Mol Sci"},{"issue":"3","key":"2375_CR156","doi-asserted-by":"publisher","first-page":"1207","DOI":"10.7150\/ijbs.123812","volume":"22","author":"C Ma","year":"2026","unstructured":"Ma C, Yang L, Li W, Shangguan W, Huang W, Li Z et al (2026) The role of estrogen signaling pathway and targeted therapy exploration in urological tumors. Int J Biol Sci 22(3):1207","journal-title":"Int J Biol Sci"},{"key":"2375_CR157","doi-asserted-by":"crossref","unstructured":"Esquea EM, Young RG, Ciraku L, Merzy J, Ahmed NN, Talarico AN et al (2024) ACSS2 regulates ferroptosis in an E2F1-dependent manner in breast cancer brain metastatic cells. openRxiv","DOI":"10.1101\/2024.10.18.619082"},{"key":"2375_CR158","doi-asserted-by":"publisher","first-page":"1591172","DOI":"10.3389\/fimmu.2025.1591172","volume":"16","author":"Y Liu","year":"2025","unstructured":"Liu Y, Zhan J, Wang J, Zeng X, Liu S, Huang L et al (2025) Ferroptosis: a double-edged sword that enhances radiation sensitivity and facilitates radiation-induced injury in tumors. Front Immunol 16:1591172","journal-title":"Front Immunol"},{"issue":"10","key":"2375_CR159","doi-asserted-by":"publisher","first-page":"2707","DOI":"10.3390\/cells10102707","volume":"10","author":"B Li","year":"2021","unstructured":"Li B, Huang Y, Ming H, Nice EC, Xuan R, Huang C (2021) Redox control of the dormant cancer cell life cycle. Cells 10(10):2707","journal-title":"Cells"},{"issue":"4","key":"2375_CR160","doi-asserted-by":"publisher","first-page":"954","DOI":"10.7150\/jca.50137","volume":"12","author":"A Maiti","year":"2021","unstructured":"Maiti A, Hait NC (2021) Autophagy-mediated tumor cell survival and progression of breast cancer metastasis to the brain. J Cancer 12(4):954\u2013964","journal-title":"J Cancer"},{"issue":"3","key":"2375_CR161","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1016\/j.ccell.2018.02.001","volume":"33","author":"T Schild","year":"2018","unstructured":"Schild T, Low V, Blenis J, Gomes AP (2018) Unique metabolic adaptations dictate distal organ-specific metastatic colonization. Cancer Cell 33(3):347\u2013354","journal-title":"Cancer Cell"},{"issue":"2","key":"2375_CR162","doi-asserted-by":"publisher","first-page":"201","DOI":"10.3390\/antiox14020201","volume":"14","author":"S Li","year":"2025","unstructured":"Li S, Yuan H, Li L, Li Q, Lin P, Li K (2025) Oxidative stress and reprogramming of lipid metabolism in cancers. Antioxidants 14(2):201","journal-title":"Antioxidants"},{"issue":"5","key":"2375_CR163","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.3390\/cells10051009","volume":"10","author":"D Qin","year":"2021","unstructured":"Qin D, Wang J, Le A, Wang TJ, Chen X, Wang J (2021) Traumatic brain injury: ultrastructural features in neuronal ferroptosis, glial cell activation and polarization, and blood\u2013brain barrier breakdown. Cells 10(5):1009","journal-title":"Cells"},{"key":"2375_CR164","doi-asserted-by":"crossref","unstructured":"Badr OI, Mustafa FA, Radwan BA, Abdulfatah AM, Ragab AN, Sleem HM (2025) Ferritinophagy as a double-edged sword in cancer: novel insights into therapeutic targeting of iron-driven ferroptosis. Cell Biochem Biophys 1\u201319","DOI":"10.1007\/s12013-025-01953-6"},{"key":"2375_CR165","doi-asserted-by":"crossref","unstructured":"Zhang Z, Tan Y, Huang C, Wei X (2023) Redox signaling in drug-tolerant persister cells as an emerging therapeutic target. EBioMedicine 89:104483","DOI":"10.1016\/j.ebiom.2023.104483"},{"issue":"5","key":"2375_CR166","doi-asserted-by":"publisher","first-page":"521","DOI":"10.3892\/ol.2024.14654","volume":"28","author":"W Xiao","year":"2024","unstructured":"Xiao W, Xu C (2024) Cystine\/cysteine metabolism regulates the progression and response to treatment of triple\u2013negative breast cancer. Oncol Lett 28(5):521","journal-title":"Oncol Lett"},{"issue":"49","key":"2375_CR167","doi-asserted-by":"publisher","first-page":"e11199","DOI":"10.1002\/adfm.202511199","volume":"35","author":"F Gao","year":"2025","unstructured":"Gao F, Liu H, Liu J, Chen C (2025) Burgeoning strategies for cancer therapy based on ferroptosis induced by nanomaterials. Adv Funct Mater 35(49):e11199","journal-title":"Adv Funct Mater"},{"issue":"4","key":"2375_CR168","doi-asserted-by":"publisher","first-page":"1897","DOI":"10.1021\/acs.chemrev.4c00546","volume":"125","author":"W Xu","year":"2025","unstructured":"Xu W, Guan G, Yue R, Dong Z, Lei L, Kang H et al (2025) Chemical design of magnetic nanomaterials for imaging and ferroptosis-based cancer therapy. Chem Rev 125(4):1897\u20131961","journal-title":"Chem Rev"},{"issue":"9","key":"2375_CR169","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.3390\/antiox14091121","volume":"14","author":"A Nowacka","year":"2025","unstructured":"Nowacka A, \u015aniegocki M, Zi\u00f3\u0142kowska E (2025) Oxidative stress and antioxidants in glioblastoma: mechanisms of action, therapeutic effects and future directions. Antioxidants 14(9):1121","journal-title":"Antioxidants"},{"key":"2375_CR170","doi-asserted-by":"publisher","first-page":"910292","DOI":"10.3389\/fphar.2022.910292","volume":"13","author":"F-J Li","year":"2022","unstructured":"Li F-J, Long H-Z, Zhou Z-W, Luo H-Y, Xu S-G, Gao L-C (2022) System Xc\u2013\/GSH\/GPX4 axis: an important antioxidant system for the ferroptosis in drug-resistant solid tumor therapy. Front Pharmacol 13:910292","journal-title":"Front Pharmacol"},{"issue":"10","key":"2375_CR171","doi-asserted-by":"publisher","first-page":"4557","DOI":"10.7150\/thno.38069","volume":"10","author":"P Mi","year":"2020","unstructured":"Mi P (2020) Stimuli-responsive nanocarriers for drug delivery, tumor imaging, therapy and theranostics. Theranostics 10(10):4557","journal-title":"Theranostics"},{"issue":"50","key":"2375_CR172","doi-asserted-by":"publisher","first-page":"e202309160","DOI":"10.1002\/anie.202309160","volume":"62","author":"X Dai","year":"2023","unstructured":"Dai X, Xie Y, Feng W, Chen Y (2023) Nanomedicine-enabled chemical regulation of reactive X species for versatile disease treatments. Angew Chem Int Ed 62(50):e202309160","journal-title":"Angew Chem Int Ed"},{"issue":"12","key":"2375_CR173","doi-asserted-by":"publisher","first-page":"1180","DOI":"10.1038\/ncb3064","volume":"16","author":"JP Friedmann Angeli","year":"2014","unstructured":"Friedmann Angeli JP, Schneider M, Proneth B, Tyurina YY, Tyurin VA, Hammond VJ et al (2014) Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice. Nat Cell Biol 16(12):1180\u20131191","journal-title":"Nat Cell Biol"},{"issue":"4","key":"2375_CR174","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1038\/s41418-023-01112-5","volume":"30","author":"L Koerner","year":"2023","unstructured":"Koerner L, Schmiel M, Yang TP, Peifer M, Buettner R, Pasparakis M (2023) NEMO- and RelA-dependent NF-kappaB signaling promotes small cell lung cancer. Cell Death Differ 30(4):938\u2013951","journal-title":"Cell Death Differ"},{"issue":"10","key":"2375_CR175","doi-asserted-by":"publisher","first-page":"800","DOI":"10.1038\/nsmb.3460","volume":"24","author":"JA Letts","year":"2017","unstructured":"Letts JA, Sazanov LA (2017) Clarifying the supercomplex: the higher-order organization of the mitochondrial electron transport chain. Nat Struct Mol Biol 24(10):800\u2013808","journal-title":"Nat Struct Mol Biol"},{"issue":"1","key":"2375_CR176","doi-asserted-by":"publisher","first-page":"16056","DOI":"10.1038\/cddiscovery.2016.56","volume":"2","author":"SB Berger","year":"2016","unstructured":"Berger SB, Bertin J, Gough PJ (2016) Life after death: RIP1 and RIP3 move beyond necroptosis. Cell Death Discov 2(1):16056","journal-title":"Cell Death Discov"},{"issue":"1","key":"2375_CR177","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1186\/s13018-025-06033-2","volume":"20","author":"Y Zhang","year":"2025","unstructured":"Zhang Y, Gao Y, Liu S, Yang G, Rong Y, Wu D et al (2025) VMP1 attenuates ferroptosis and mitochondrial dysfunction in nucleus pulposus cells through the PINK1\/Parkin-mediated mitophagy pathway. J Orthop Surg Res 20(1):630","journal-title":"J Orthop Surg Res"},{"issue":"9","key":"2375_CR178","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1038\/nrm920","volume":"3","author":"A Heinrichs","year":"2002","unstructured":"Heinrichs A (2002) Master switch. Nat Rev Mol Cell Biol 3(9):636","journal-title":"Nat Rev Mol Cell Biol"},{"key":"2375_CR179","doi-asserted-by":"crossref","unstructured":"Murphy J (2015) Faculty opinions recommendation of activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis. Faculty opinions \u2013 post-publication peer review of the biomedical literature: H1 connect","DOI":"10.3410\/f.718284131.793511046"},{"issue":"5","key":"2375_CR180","doi-asserted-by":"publisher","first-page":"2181","DOI":"10.1007\/s11010-021-04087-4","volume":"476","author":"AK Shendge","year":"2021","unstructured":"Shendge AK, Panja S, Mandal N (2021) Tropical lichen, Dirinaria consimilis, induces ROS-mediated activation of MAPKs and triggers caspase cascade mediated apoptosis in brain and cervical cancer cells. Mol Cell Biochem 476(5):2181\u20132192","journal-title":"Mol Cell Biochem"},{"issue":"5","key":"2375_CR181","doi-asserted-by":"publisher","first-page":"1060","DOI":"10.1016\/j.cell.2012.03.042","volume":"149","author":"SJ Dixon","year":"2012","unstructured":"Dixon SJ, Lemberg KM, Lamprecht MR, Skouta R, Zaitsev EM, Gleason CE et al (2012) Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell 149(5):1060\u20131072","journal-title":"Cell"},{"issue":"1","key":"2375_CR182","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1038\/nchembio.2239","volume":"13","author":"S Doll","year":"2017","unstructured":"Doll S, Proneth B, Tyurina YY, Panzilius E, Kobayashi S, Ingold I et al (2017) ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition. Nat Chem Biol 13(1):91\u201398","journal-title":"Nat Chem Biol"},{"issue":"1","key":"2375_CR183","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1186\/s12935-021-02088-3","volume":"21","author":"M Zhu","year":"2021","unstructured":"Zhu M, Wang Y, Wang F, Li L, Qiu X (2021) CircFBXL5 promotes the 5-FU resistance of breast cancer via modulating miR-216b\/HMGA2 axis. Cancer Cell Int 21(1):384","journal-title":"Cancer Cell Int"},{"key":"2375_CR184","doi-asserted-by":"crossref","unstructured":"Mercurio A (2017) Faculty opinions recommendation of dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway. Faculty opinions \u2013 post-publication peer review of the biomedical literature: H1 connect","DOI":"10.3410\/f.727777471.793537328"},{"key":"2375_CR185","doi-asserted-by":"publisher","first-page":"S43","DOI":"10.1016\/j.freeradbiomed.2025.10.125","volume":"240","author":"LV Ramirez","year":"2025","unstructured":"Ramirez LV, Puente-Cobacho B, Esteo C, Altea-Manzano P, Sanchez-Rovira P, Mart\u00edn-Salvago MD et al (2025) Metabolic rewiring of dormant breast cancer cells: ACSL3-mediated monounsaturated fatty acids incorporation prevents ferroptosis. Free Radic Biol Med 240:S43","journal-title":"Free Radic Biol Med"},{"key":"2375_CR186","doi-asserted-by":"publisher","first-page":"110045","DOI":"10.1016\/j.cellsig.2021.110045","volume":"85","author":"A Wu","year":"2021","unstructured":"Wu A, Zhang L, Luo N, Zhang L, Li L, Liu Q (2021) Limb-bud and heart (LBH) inhibits cellular migration, invasion and epithelial-mesenchymal transition in nasopharyngeal carcinoma via downregulating alphaB-crystallin expression. Cell Signal 85:110045","journal-title":"Cell Signal"},{"key":"2375_CR187","doi-asserted-by":"crossref","unstructured":"Fernandez-Gines R, Encinar JA, Hayes JD, Oliva B, Rodriguez-Franco MI, Rojo AI et al (2022) Corrigendum to \u201cAn inhibitor of interaction between the transcription factor NRF2 and the E3 ubiquitin ligase adapter beta-TrCP delivers anti-inflammatory responses in mouse liver\u201d [Redox Biol 55:102396]. Redox Biol (2022) 55:102428","DOI":"10.1016\/j.redox.2022.102428"},{"key":"2375_CR188","doi-asserted-by":"crossref","unstructured":"Zhu F, Liu Y, Wang X, Wu Z (2023) Ozone treatment attenuates the ferroptosis induced by cerebral ischemia\/reperfusion injury via activation of the Nrf2\/Slc7a11\/Gpx4 signaling pathway. Research Square Platform LLC","DOI":"10.21203\/rs.3.rs-3249587\/v1"},{"key":"2375_CR189","doi-asserted-by":"crossref","unstructured":"Zacharakis, N., Huq, L. M., Seitter, S. J., Kim, S. P., Gartner, J. J.,et al (2022). Breast cancers are immunogenic: immunologic analyses and a phase II pilot clinical trial using mutation-reactive autologous lymphocytes. Journal of Clinical Oncology, 40(16), 1741-1754.","DOI":"10.1200\/JCO.21.02170"},{"key":"2375_CR190","doi-asserted-by":"crossref","unstructured":"Liu S, Wu W, Fang L, Rao Z, Peng J, Wang X, Yu C, Wang J (2025) Ferroptosis\/apoptosis induction by an iridium complex encapsulated in PLGA nanoparticles enhances efficacy and reduces toxicity in breast cancer. J Med Chem 69:146\u2013162","DOI":"10.1021\/acs.jmedchem.5c02025"},{"key":"2375_CR191","unstructured":"WITHDRAWN (2022) Hypoxia enhanced glioblastoma resistance to erastin-induced ferroptosis by up-regulating GPX4 via PI3K\/AKT\/HIF-1\u03b1 axis. Springer Science and Business Media LLC"},{"key":"2375_CR192","doi-asserted-by":"crossref","unstructured":"Crawford DR et al (2016) Commentary on Rupestonic acid derivative YZH-106 suppresses influenza virus replication by activation of heme oxygenase-1-mediated interferon response by Ma [Free Radic Biol Med 96:347\u2013361]. Free Radic Biol Med (2016) 96:465-4666","DOI":"10.1016\/j.freeradbiomed.2016.05.018"},{"key":"2375_CR193","doi-asserted-by":"crossref","unstructured":"He J, Abikoye AM, McLaughlin BP, Middleton RS, Sheldon R, Jones RG et al (2022) Reprogramming of iron metabolism confers ferroptosis resistance in ECM-detached cells. openRxiv","DOI":"10.1101\/2022.09.23.509253"},{"issue":"24","key":"2375_CR194","doi-asserted-by":"publisher","first-page":"4127","DOI":"10.3390\/cells11244127","volume":"11","author":"Y Jin","year":"2022","unstructured":"Jin Y, Qiu J, Lu X, Li G (2022) C-MYC inhibited ferroptosis and promoted immune evasion in ovarian cancer cells through NCOA4 mediated ferritin autophagy. Cells 11(24):4127","journal-title":"Cells"},{"issue":"5","key":"2375_CR195","doi-asserted-by":"publisher","first-page":"e638","DOI":"10.1038\/cddis.2013.167","volume":"4","author":"A Notte","year":"2013","unstructured":"Notte A, Ninane N, Arnould T, Michiels C (2013) Hypoxia counteracts taxol-induced apoptosis in MDA-MB-231 breast cancer cells: role of autophagy and JNK activation. Cell Death Dis 4(5):e638","journal-title":"Cell Death Dis"},{"key":"2375_CR196","doi-asserted-by":"crossref","unstructured":"Correction to Supporting Information for Li et al., USP8-governed GPX4 homeostasis orchestrates ferroptosis and cancer immunotherapy (2024). Proc Natl Acad Sci USA 121(25):e2409669121","DOI":"10.1073\/pnas.2409669121"},{"issue":"10","key":"2375_CR197","doi-asserted-by":"publisher","first-page":"2843","DOI":"10.1038\/s41418-021-00859-z","volume":"28","author":"X Chen","year":"2021","unstructured":"Chen X, Kang R, Kroemer G, Tang D (2021) Organelle-specific regulation of ferroptosis. Cell Death Differ 28(10):2843\u20132856","journal-title":"Cell Death Differ"},{"issue":"9\u201310","key":"2375_CR198","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1007\/s10495-022-01755-8","volume":"27","author":"Y Chen","year":"2022","unstructured":"Chen Y, Ren W, Wang Q, He Y, Ma D, Cai Z (2022) The regulation of necroptosis by ubiquitylation. Apoptosis 27(9\u201310):668\u2013684","journal-title":"Apoptosis"},{"issue":"1","key":"2375_CR199","doi-asserted-by":"publisher","first-page":"2243","DOI":"10.1038\/s41467-020-16103-0","volume":"11","author":"A Gaub","year":"2020","unstructured":"Gaub A, Sheikh BN, Basilicata MF, Vincent M, Nizon M, Colson C et al (2020) Evolutionary conserved NSL complex\/BRD4 axis controls transcription activation via histone acetylation. Nat Commun 11(1):2243","journal-title":"Nat Commun"},{"key":"2375_CR200","doi-asserted-by":"publisher","unstructured":"Correction to: MicroRNA-26b reduces cell viability by inhibition of nicotinamide phosphoribosyltransferase in breast cancer cells (2022) DNA Cell Biol 41(8):735\u2013741. DNA Cell Biol (2022) 41(10):917 https:\/\/doi.org\/10.1089\/dna.2022.0214","DOI":"10.1089\/dna.2022.0214"},{"key":"2375_CR201","unstructured":"(2022) Correction for Tang et al., Neural transcription factor Pou4f1 promotes renal fibrosis via macrophage-myofibroblast transition. Proc Natl Acad Sci USA 119(10):e2200781119"},{"issue":"10","key":"2375_CR202","doi-asserted-by":"publisher","first-page":"1546","DOI":"10.1002\/cncr.33606","volume":"127","author":"C Printz","year":"2021","unstructured":"Printz C (2021) Immune factors tied to aggressive breast cancers in black patients. Cancer 127(10):1546","journal-title":"Cancer"},{"key":"2375_CR203","doi-asserted-by":"crossref","unstructured":"Qin, J., Lee, H. J., Wu, S. P., Lin, S. C., Lanz, R. B., et al (2014). Androgen deprivation\u2013induced NCoA2 promotes metastatic and castration-resistant prostate cancer. The Journal of clinical investigation, 124(11), 5013-5026.","DOI":"10.1172\/JCI76412"},{"key":"2375_CR204","unstructured":"Kulkarni CA, Brookes P et al (2019) Many routes from glycolysis to histone PTMs. Nature matters arising response to: Zhang metabolic regulation of gene expression by histone lactylation. Nature 574(7779):575\u2013580"},{"issue":"10","key":"2375_CR205","doi-asserted-by":"publisher","first-page":"1761","DOI":"10.1016\/j.immuni.2022.09.011","volume":"55","author":"J Li","year":"2022","unstructured":"Li J, Ruffell B (2022) Cytokines drive prostate cancer lineage plasticity. Immunity 55(10):1761\u20131763","journal-title":"Immunity"},{"key":"2375_CR206","doi-asserted-by":"publisher","first-page":"858","DOI":"10.1038\/bonekey.2016.89","volume":"13","author":"K Nakajima","year":"2016","unstructured":"Nakajima K et al (2016) Galectin-3 helps drive bone metastasis of prostate and breast cancers. IBMS BoneKEy 13:858","journal-title":"IBMS BoneKEy"},{"issue":"22","key":"2375_CR207","doi-asserted-by":"publisher","first-page":"4840","DOI":"10.1158\/1078-0432.CCR-22-2140","volume":"28","author":"P Sharma","year":"2022","unstructured":"Sharma P (2022) Time to optimize deescalation strategies in triple-negative breast cancer? Clin Cancer Res 28(22):4840\u20134842","journal-title":"Clin Cancer Res"},{"issue":"1","key":"2375_CR208","doi-asserted-by":"publisher","first-page":"1431","DOI":"10.1038\/s41467-023-37149-w","volume":"14","author":"B Gan","year":"2023","unstructured":"Gan B (2023) Ferroptosis hijacking by Mycobacterium tuberculosis. Nat Commun 14(1):1431","journal-title":"Nat Commun"},{"key":"2375_CR209","doi-asserted-by":"publisher","first-page":"929363","DOI":"10.3389\/fonc.2022.929363","volume":"12","author":"W Zhang","year":"2022","unstructured":"Zhang W, Zhang S, Wang Z (2022) Prognostic value of 12 m7G methylation-related miRNA markers and their correlation with immune infiltration in breast cancer. Front Oncol 12:929363","journal-title":"Front Oncol"},{"key":"2375_CR210","doi-asserted-by":"publisher","first-page":"S143","DOI":"10.1016\/S0090-8258(22)01490-1","volume":"166","author":"S Gabrilovich","year":"2022","unstructured":"Gabrilovich S, Devor E, Bender D, Goodheart M, Bosquet JG (2022) ScRNA seq can identify different cell populations in ovarian cancer Bulk RNA seq experiments (269). Gynecol Oncol 166:S143\u2013S144","journal-title":"Gynecol Oncol"},{"key":"2375_CR211","unstructured":"Vanguri, R. S., & Shah, S. P. (2022). Multimodal data integration improves immunotherapy response prediction. Nature Cancer."},{"key":"2375_CR212","doi-asserted-by":"publisher","first-page":"101017","DOI":"10.1016\/j.neo.2024.101017","volume":"55","author":"B Fu","year":"2024","unstructured":"Fu B, Lou Y, Wu P, Lu X, Xu C (2024) Emerging role of necroptosis, pyroptosis, and ferroptosis in breast cancer: new dawn for overcoming therapy resistance. Neoplasia 55:101017","journal-title":"Neoplasia"},{"issue":"1","key":"2375_CR213","doi-asserted-by":"publisher","first-page":"e18044","DOI":"10.1111\/jcmm.18044","volume":"28","author":"A Ge","year":"2024","unstructured":"Ge A, He Q, Zhao D, Li Y, Chen J, Deng Y et al (2024) Mechanism of ferroptosis in breast cancer and research progress of natural compounds regulating ferroptosis. J Cell Mol Med 28(1):e18044","journal-title":"J Cell Mol Med"},{"issue":"3\u20134","key":"2375_CR214","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1007\/s10495-023-01904-7","volume":"29","author":"X Liu","year":"2024","unstructured":"Liu X, Miao M, Sun J, Wu J, Qin X (2024) PANoptosis: a potential new target for programmed cell death in breast cancer treatment and prognosis. Apoptosis 29(3\u20134):277\u2013288","journal-title":"Apoptosis"},{"issue":"1","key":"2375_CR215","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1111\/imr.13251","volume":"321","author":"Y Xi","year":"2024","unstructured":"Xi Y, Chen L, Tang J, Yu B, Shen W, Niu X (2024) Amplifying eat me signal by immunogenic cell death for potentiating cancer immunotherapy. Immunol Rev 321(1):94\u2013114","journal-title":"Immunol Rev"},{"issue":"3","key":"2375_CR216","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1007\/s10549-024-07387-7","volume":"207","author":"K Mokhtarpour","year":"2024","unstructured":"Mokhtarpour K, Razi S, Rezaei N (2024) Ferroptosis as a promising targeted therapy for triple negative breast cancer. Breast Cancer Res Treat 207(3):497\u2013513","journal-title":"Breast Cancer Res Treat"},{"key":"2375_CR217","doi-asserted-by":"publisher","first-page":"1437022","DOI":"10.3389\/fphar.2024.1437022","volume":"15","author":"Z Chen","year":"2024","unstructured":"Chen Z, Zhao Y (2024) The mechanism underlying metastasis in triple-negative breast cancer: focusing on the interplay between ferroptosis, epithelial-mesenchymal transition, and non-coding RNAs. Front Pharmacol 15:1437022","journal-title":"Front Pharmacol"},{"issue":"17","key":"2375_CR218","doi-asserted-by":"publisher","first-page":"9703","DOI":"10.3390\/ijms25179703","volume":"25","author":"J Qian","year":"2024","unstructured":"Qian J, Zhao L, Xu L, Zhao J, Tang Y, Yu M et al (2024) Cell death: mechanisms and potential targets in breast cancer therapy. Int J Mol Sci 25(17):9703","journal-title":"Int J Mol Sci"},{"issue":"19","key":"2375_CR219","doi-asserted-by":"publisher","first-page":"4756","DOI":"10.3390\/cancers13194756","volume":"13","author":"R Kim","year":"2021","unstructured":"Kim R, Kin T (2021) Current and future therapies for immunogenic cell death and related molecules to potentially cure primary breast cancer. Cancers 13(19):4756","journal-title":"Cancers (Basel)"},{"key":"2375_CR220","doi-asserted-by":"publisher","first-page":"870914","DOI":"10.3389\/fonc.2022.870914","volume":"12","author":"M Xu","year":"2022","unstructured":"Xu M, Lu JH, Zhong YZ, Jiang J, Shen YZ, Su JY et al (2022) Immunogenic cell death-relevant damage-associated molecular patterns and sensing receptors in triple-negative breast cancer molecular subtypes and implications for immunotherapy. Front Oncol 12:870914","journal-title":"Front Oncol"},{"issue":"3","key":"2375_CR221","doi-asserted-by":"publisher","first-page":"361","DOI":"10.3390\/cancers18030361","volume":"18","author":"K Dynarowicz","year":"2026","unstructured":"Dynarowicz K, Bartusik-Aebisher D, Czech S, Kawczyk-Krupka A, Aebisher D (2026) A decade of innovation in breast cancer (2015\u20132025): a comprehensive review of clinical trials, targeted therapies and molecular perspectives. Cancers 18(3):361","journal-title":"Cancers (Basel)"},{"key":"2375_CR222","first-page":"793","volume":"17","author":"X Xu","year":"2025","unstructured":"Xu X, Li X (2025) The role of the xihuang pill in inhibiting triple-negative breast cancer through immunogenic cell death. Breast Cancer Targets Ther 17:793\u2013803","journal-title":"Breast Cancer (Dove Med Press)"},{"key":"2375_CR223","doi-asserted-by":"crossref","unstructured":"Papadopoulos Z, Antar Y, Dieter IS, Peeters F, Plaza-Sirvent C, Karges J (2025) Gallium III complex induces immunogenic cell death hallmarks for chemoimmunotherapy. J Med Chem 68:15980\u201315990","DOI":"10.1021\/acs.jmedchem.5c00969"},{"issue":"1","key":"2375_CR224","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1007\/s10238-024-01482-1","volume":"24","author":"Y Wang","year":"2024","unstructured":"Wang Y, Yang R, Xie Y, Zhou XQ, Yang JF, Shi YY et al (2024) Comprehensive review of drug-mediated ICD inhibition of breast cancer: mechanism, status, and prospects. Clin Exp Med 24(1):230","journal-title":"Clin Exp Med"},{"issue":"12","key":"2375_CR225","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1007\/s12032-022-01782-0","volume":"39","author":"K Kawaguchi","year":"2022","unstructured":"Kawaguchi K, Maeshima Y, Toi M (2022) Tumor immune microenvironment and systemic response in breast cancer. Med Oncol 39(12):208","journal-title":"Med Oncol"},{"issue":"6","key":"2375_CR226","doi-asserted-by":"publisher","first-page":"e12228","DOI":"10.1002\/jev2.12228","volume":"11","author":"MS Njock","year":"2022","unstructured":"Njock MS, O\u2019Grady T, Nivelles O, Lion M, Jacques S, Cambier M et al (2022) Endothelial extracellular vesicles promote tumour growth by tumour-associated macrophage reprogramming. J Extracell Vesicles 11(6):e12228","journal-title":"J Extracell Vesicles"},{"issue":"1","key":"2375_CR227","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1186\/s12967-025-06246-3","volume":"23","author":"K Zhang","year":"2025","unstructured":"Zhang K, Guo L, Li X, Hu Y, Luo N (2025) Cancer-associated fibroblasts promote doxorubicin resistance in triple-negative breast cancer through enhancing ZFP64 histone lactylation to regulate ferroptosis. J Transl Med 23(1):247","journal-title":"J Transl Med"},{"issue":"4","key":"2375_CR228","doi-asserted-by":"publisher","first-page":"3925","DOI":"10.1007\/s00210-024-03488-8","volume":"398","author":"Y Gao","year":"2025","unstructured":"Gao Y, Huang Y, Zhao Y, Hu P (2025) Cancer-associated fibroblast-secreted exosomal miR-454-3p inhibits lipid metabolism and ferroptosis in breast cancer by targeting ACSL4. Naunyn Schmiedebergs Arch Pharmacol 398(4):3925\u20133937","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"issue":"7","key":"2375_CR229","doi-asserted-by":"publisher","first-page":"2729","DOI":"10.21873\/anticanres.17643","volume":"45","author":"D Kamyan","year":"2025","unstructured":"Kamyan D, Elemam NM, Alkhayyal N, Talaat IM, Bendardaf R (2025) Unlocking new frontiers in breast cancer: the role of the tumor microenvironment, cutting-edge therapies, and immunotherapy. Anticancer Res 45(7):2729\u20132747","journal-title":"Anticancer Res"},{"key":"2375_CR230","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/j.semcancer.2019.07.028","volume":"60","author":"BS Hill","year":"2020","unstructured":"Hill BS, Sarnella A, D\u2019Avino G, Zannetti A (2020) Recruitment of stromal cells into tumour microenvironment promote the metastatic spread of breast cancer. Semin Cancer Biol 60:202\u2013213","journal-title":"Semin Cancer Biol"},{"key":"2375_CR231","doi-asserted-by":"publisher","first-page":"1063051","DOI":"10.3389\/fonc.2023.1063051","volume":"13","author":"JA Thomas","year":"2023","unstructured":"Thomas JA, Gireesh Moly AG, Xavier H, Suboj P, Ladha A, Gupta G et al (2023) Enhancement of immune surveillance in breast cancer by targeting hypoxic tumor endothelium: can it be an immunological switch point? Front Oncol 13:1063051","journal-title":"Front Oncol"},{"issue":"1","key":"2375_CR232","doi-asserted-by":"publisher","first-page":"7457","DOI":"10.1038\/s41467-025-62399-1","volume":"16","author":"Y Zhu","year":"2025","unstructured":"Zhu Y, Brulois KF, Dinh TT, Pan J, Butcher EC (2025) COUP-TFII-mediated reprogramming of the vascular endothelium counteracts tumor immune evasion. Nat Commun 16(1):7457","journal-title":"Nat Commun"},{"key":"2375_CR233","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1016\/j.actbio.2021.09.003","volume":"135","author":"S Hu","year":"2021","unstructured":"Hu S, Ma J, Su C, Chen Y, Shu Y, Qi Z et al (2021) Engineered exosome-like nanovesicles suppress tumor growth by reprogramming tumor microenvironment and promoting tumor ferroptosis. Acta Biomater 135:567\u2013581","journal-title":"Acta Biomater"},{"issue":"1","key":"2375_CR234","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1186\/s11658-025-00789-5","volume":"30","author":"Y Liu","year":"2025","unstructured":"Liu Y, He J, Chen J, Chen T, Li W, Yang Z et al (2025) Programmed cell death in triple-negative breast cancer. Cell Mol Biol Lett 30(1):111","journal-title":"Cell Mol Biol Lett"},{"issue":"11","key":"2375_CR235","doi-asserted-by":"publisher","first-page":"3272","DOI":"10.7150\/jca.94669","volume":"15","author":"X Xu","year":"2024","unstructured":"Xu X, Wang X, Zheng Z, Guo Y, He G, Wang Y et al (2024) Neutrophil extracellular traps in breast cancer: roles in metastasis and beyond. J Cancer 15(11):3272\u20133283","journal-title":"J Cancer"},{"key":"2375_CR236","doi-asserted-by":"publisher","first-page":"110760","DOI":"10.1016\/j.abb.2026.110760","volume":"779","author":"L Montero-Leon","year":"2026","unstructured":"Montero-Leon L, Cruz-Gregorio A, Hernandez-Cruz EY, Sciutto E, Fragoso G, Pedraza-Chaverri J (2026) Unlocking ferroptosis: a novel link between triple-negative breast cancer and immune regulation. Arch Biochem Biophys 779:110760","journal-title":"Arch Biochem Biophys"},{"issue":"5","key":"2375_CR237","doi-asserted-by":"publisher","first-page":"2753","DOI":"10.21873\/anticanres.15754","volume":"42","author":"Y Chung","year":"2022","unstructured":"Chung Y, Kim S, Kim HS, Do SI (2022) High receptor-interacting serine\/threonine-protein kinase 3 (RIP3) expression serves as an independent poor prognostic factor for triple-negative breast carcinoma. Anticancer Res 42(5):2753\u20132761","journal-title":"Anticancer Res"},{"issue":"1","key":"2375_CR238","doi-asserted-by":"publisher","first-page":"34","DOI":"10.4048\/jbc.2021.24.e12","volume":"24","author":"KY Won","year":"2021","unstructured":"Won KY, Min SY, Song JY, Lim SJ, Han SA (2021) Clinical significance of receptor-interacting protein 3 and Parkin, essential molecules for necroptosis, in breast cancer. J Breast Cancer 24(1):34\u201348","journal-title":"J Breast Cancer"},{"issue":"6","key":"2375_CR239","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1038\/cr.2015.56","volume":"25","author":"GB Koo","year":"2015","unstructured":"Koo GB, Morgan MJ, Lee DG, Kim WJ, Yoon JH, Koo JS et al (2015) Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics. Cell Res 25(6):707\u2013725","journal-title":"Cell Res"},{"issue":"7","key":"2375_CR240","doi-asserted-by":"publisher","first-page":"2234","DOI":"10.1038\/s41418-020-0499-y","volume":"27","author":"CC Lin","year":"2020","unstructured":"Lin CC, Mabe NW, Lin YT, Yang WH, Tang X, Hong L et al (2020) RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence. Cell Death Differ 27(7):2234\u20132247","journal-title":"Cell Death Differ"},{"issue":"2","key":"2375_CR241","doi-asserted-by":"publisher","first-page":"317","DOI":"10.3390\/antiox10020317","volume":"10","author":"N Lee","year":"2021","unstructured":"Lee N, Carlisle AE, Peppers A, Park SJ, Doshi MB, Spears ME et al (2021) xCT-driven expression of GPX4 determines sensitivity of breast cancer cells to ferroptosis inducers. Antioxidants 10(2):317","journal-title":"Antioxid (Basel)"},{"key":"2375_CR242","doi-asserted-by":"publisher","first-page":"103560","DOI":"10.1016\/j.ebiom.2021.103560","volume":"71","author":"R Sha","year":"2021","unstructured":"Sha R, Xu Y, Yuan C, Sheng X, Wu Z, Peng J et al (2021) Predictive and prognostic impact of ferroptosis-related genes ACSL4 and GPX4 on breast cancer treated with neoadjuvant chemotherapy. EBioMedicine 71:103560","journal-title":"EBioMedicine"},{"issue":"1","key":"2375_CR243","doi-asserted-by":"publisher","first-page":"9550","DOI":"10.1038\/s41467-024-53837-7","volume":"15","author":"MT Herrera-Abreu","year":"2024","unstructured":"Herrera-Abreu MT, Guan J, Khalid U, Ning J, Costa MR, Chan J et al (2024) Inhibition of GPX4 enhances CDK4\/6 inhibitor and endocrine therapy activity in breast cancer. Nat Commun 15(1):9550","journal-title":"Nat Commun"},{"issue":"1","key":"2375_CR244","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1038\/s41523-024-00685-9","volume":"10","author":"K Hu","year":"2024","unstructured":"Hu K, Qiu J, Hu Y, Wang Y, Yu C, Wu Y (2024) Efficacy of FERscore in predicting sensitivity to ferroptosis inducers in breast cancer. NPJ Breast Cancer 10(1):74","journal-title":"NPJ Breast Cancer"},{"issue":"1","key":"2375_CR245","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1186\/s13058-018-1030-y","volume":"20","author":"H Zhang","year":"2018","unstructured":"Zhang H, Fredericks T, Xiong G, Qi Y, Rychahou PG, Li JD et al (2018) Membrane associated collagen XIII promotes cancer metastasis and enhances anoikis resistance. Breast Cancer Res 20(1):116","journal-title":"Breast Cancer Res"},{"issue":"6","key":"2375_CR246","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.1038\/s41388-020-01588-2","volume":"40","author":"H Yousefi","year":"2021","unstructured":"Yousefi H, Vatanmakanian M, Mahdiannasser M, Mashouri L, Alahari NV, Monjezi MR et al (2021) Understanding the role of integrins in breast cancer invasion, metastasis, angiogenesis, and drug resistance. Oncogene 40(6):1043\u20131063","journal-title":"Oncogene"},{"key":"2375_CR247","doi-asserted-by":"crossref","unstructured":"Mu Y, Fan Y, He L, Hu N, Xue H, Guan X et al (2023) Enhanced cancer immunotherapy through synergistic ferroptosis and immune checkpoint blockade using cell membrane-coated nanoparticles. Cancer Nanotechnol 14(1):83","DOI":"10.1186\/s12645-023-00234-2"},{"issue":"2","key":"2375_CR248","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1007\/s10495-026-02258-6","volume":"31","author":"F Liu","year":"2026","unstructured":"Liu F, Xiao JH, Song YJ, Zeng CC (2026) Ferroptosis and its role in immune modulation in breast cancer. Apoptosis 31(2):49","journal-title":"Apoptosis"},{"key":"2375_CR249","doi-asserted-by":"publisher","first-page":"1611299","DOI":"10.3389\/fimmu.2025.1611299","volume":"16","author":"T Zhang","year":"2025","unstructured":"Zhang T, Gu F, Lin W, Shao H, Jiang A, Guan X (2025) Boosting cancer immunotherapy: drug delivery systems leveraging ferroptosis and immune checkpoint blockade. Front Immunol 16:1611299","journal-title":"Front Immunol"},{"issue":"1","key":"2375_CR250","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1007\/s12282-025-01792-6","volume":"33","author":"M Masuyama","year":"2026","unstructured":"Masuyama M, Shimoda M, Seto I, Kikumori K, Abe K, Masunaga N et al (2026) Targeting focal adhesion kinase inhibits cell migration and non-angiogenic vascularization in malignant breast cancer. Breast Cancer 33(1):188\u2013199","journal-title":"Breast Cancer"},{"issue":"7Supplement","key":"2375_CR251","doi-asserted-by":"publisher","first-page":"CT035","DOI":"10.1158\/1538-7445.AM2024-CT035","volume":"84","author":"C Tiu","year":"2024","unstructured":"Tiu C, Yau W, Sanchez-Perez V, Codacci-Pisanelli G, Leung C, Andrews ES et al (2024) Abstract CT035: proof-of-concept and preliminary efficacy of triple IAP blockade to maximize immunogenic cell death and induce efficient adaptive immune response: First report on the ASTEROID phase 1 trial. Cancer Res 84(7Supplement):CT035\u2013CT","journal-title":"Cancer Res"},{"key":"2375_CR252","doi-asserted-by":"publisher","first-page":"625","DOI":"10.2147\/CMAR.S503932","volume":"17","author":"LK Tan","year":"2025","unstructured":"Tan LK, Liu J, Ma CZ, Huang S, He FH, Long Y et al (2025) Iron-dependent cell death: exploring ferroptosis as a unique target in triple-negative breast cancer management. Cancer Manag Res 17:625\u2013637","journal-title":"Cancer Manag Res"},{"issue":"8","key":"2375_CR253","doi-asserted-by":"publisher","first-page":"2010","DOI":"10.1111\/cts.13317","volume":"15","author":"M Vissers","year":"2022","unstructured":"Vissers M, Heuberger J, Groeneveld GJ, Oude Nijhuis J, De Deyn PP, Hadi S et al (2022) Safety, pharmacokinetics and target engagement of novel RIPK1 inhibitor SAR443060 (DNL747) for neurodegenerative disorders: Randomized, placebo-controlled, double-blind phase I\/Ib studies in healthy subjects and patients. Clin Transl Sci 15(8):2010\u20132023","journal-title":"Clin Transl Sci"},{"issue":"1","key":"2375_CR254","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1186\/s13075-021-02468-0","volume":"23","author":"K Weisel","year":"2021","unstructured":"Weisel K, Berger S, Thorn K, Taylor PC, Peterfy C, Siddall H et al (2021) A randomized, placebo-controlled experimental medicine study of RIPK1 inhibitor GSK2982772 in patients with moderate to severe rheumatoid arthritis. Arthritis Res Ther 23(1):85","journal-title":"Arthritis Res Ther"},{"issue":"6","key":"2375_CR255","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1021\/acsmedchemlett.9b00108","volume":"10","author":"PA Harris","year":"2019","unstructured":"Harris PA, Marinis JM, Lich JD, Berger SB, Chirala A, Cox JA et al (2019) Identification of a RIP1 kinase inhibitor clinical candidate (GSK3145095) for the treatment of pancreatic cancer. ACS Med Chem Lett 10(6):857\u2013862","journal-title":"ACS Med Chem Lett"},{"key":"2375_CR256","doi-asserted-by":"crossref","unstructured":"Zare A, Petrova A, Agoumi M, Armstrong H, Bigras G, Tonkin K (2018) Erratum: Zare A et al. RIPK2: new elements in modulating inflammatory breast cancer pathogenesis. Cancers 10:184. Cancers 2018 10(11):425","DOI":"10.3390\/cancers10110425"},{"issue":"12","key":"2375_CR257","doi-asserted-by":"publisher","first-page":"2268","DOI":"10.1093\/annonc\/mdw427","volume":"27","author":"JC Soria","year":"2016","unstructured":"Soria JC, Gan HK, Blagden SP, Plummer R, Arkenau HT, Ranson M et al (2016) A phase I, pharmacokinetic and pharmacodynamic study of GSK2256098, a focal adhesion kinase inhibitor, in patients with advanced solid tumors. Ann Oncol 27(12):2268\u20132274","journal-title":"Ann Oncol"},{"issue":"1","key":"2375_CR258","doi-asserted-by":"publisher","first-page":"3055","DOI":"10.1038\/s41467-021-23316-4","volume":"12","author":"M Dai","year":"2021","unstructured":"Dai M, Yan G, Wang N, Daliah G, Edick AM, Poulet S et al (2021) In vivo genome-wide CRISPR screen reveals breast cancer vulnerabilities and synergistic mTOR\/Hippo targeted combination therapy. Nat Commun 12(1):3055","journal-title":"Nat Commun"},{"issue":"22","key":"2375_CR259","doi-asserted-by":"publisher","first-page":"3829","DOI":"10.1091\/mbc.e10-04-0353","volume":"21","author":"KA Whelan","year":"2010","unstructured":"Whelan KA, Caldwell SA, Shahriari KS, Jackson SR, Franchetti LD, Johannes GJ et al (2010) Hypoxia suppression of Bim and Bmf blocks anoikis and luminal clearing during mammary morphogenesis. Mol Biol Cell 21(22):3829\u20133837","journal-title":"Mol Biol Cell"},{"issue":"10","key":"2375_CR260","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1038\/s41589-019-0342-2","volume":"15","author":"CK Tsui","year":"2019","unstructured":"Tsui CK, Barfield RM, Fischer CR, Morgens DW, Li A, Smith BAH et al (2019) CRISPR-Cas9 screens identify regulators of antibody-drug conjugate toxicity. Nat Chem Biol 15(10):949\u2013958","journal-title":"Nat Chem Biol"},{"issue":"3","key":"2375_CR261","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1038\/s41419-018-0301-y","volume":"9","author":"MG Callow","year":"2018","unstructured":"Callow MG, Watanabe C, Wickliffe KE, Bainer R, Kummerfield S, Weng J et al (2018) CRISPR whole-genome screening identifies new necroptosis regulators and RIPK1 alternative splicing. Cell Death Dis 9(3):261","journal-title":"Cell Death Dis"},{"issue":"22","key":"2375_CR262","doi-asserted-by":"publisher","first-page":"e2502876122","DOI":"10.1073\/pnas.2502876122","volume":"122","author":"SM Lamperis","year":"2025","unstructured":"Lamperis SM, McMahon KM, Calvert AE, Rink JS, Vasan K, Pandkar MR et al (2025) CRISPR screen reveals a simultaneous targeted mechanism to reduce cancer cell selenium and increase lipid oxidation to induce ferroptosis. Proc Natl Acad Sci USA 122(22):e2502876122","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"2375_CR263","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1038\/s41419-025-07510-6","volume":"16","author":"R Deng","year":"2025","unstructured":"Deng R, Fu L, Liang H, Ai X, Liu F, Li N et al (2025) Inhibition of mitochondrial complex I induces mitochondrial ferroptosis by regulating CoQH2 levels in cancer. Cell Death Dis 16(1):254","journal-title":"Cell Death Dis"},{"issue":"1","key":"2375_CR264","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1038\/s41420-022-01251-7","volume":"8","author":"E Seidel","year":"2022","unstructured":"Seidel E, von Karstedt S (2022) Extrinsic cell death pathway plasticity: a driver of clonal evolution in cancer? Cell Death Discov 8(1):465","journal-title":"Cell Death Discov"},{"issue":"1","key":"2375_CR265","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1186\/s13059-024-03404-6","volume":"25","author":"SJ Liu","year":"2024","unstructured":"Liu SJ, Zou C, Pak J, Morse A, Pang D, Casey-Clyde T et al (2024) In vivo perturb-seq of cancer and microenvironment cells dissects oncologic drivers and radiotherapy responses in glioblastoma. Genome Biol 25(1):256","journal-title":"Genome Biol"},{"key":"2375_CR266","doi-asserted-by":"publisher","first-page":"1350935","DOI":"10.3389\/fonc.2024.1350935","volume":"14","author":"Y Shi","year":"2024","unstructured":"Shi Y, Guan Z, Cai G, Nie Y, Zhang C, Luo W et al (2024) Patient-derived organoids: a promising tool for breast cancer research. Front Oncol 14:1350935","journal-title":"Front Oncol"},{"key":"2375_CR267","doi-asserted-by":"publisher","first-page":"1455741","DOI":"10.3389\/fimmu.2024.1455741","volume":"15","author":"A Ge","year":"2024","unstructured":"Ge A, Xiang W, Li Y, Zhao D, Chen J, Daga P et al (2024) Broadening horizons: the multifaceted role of ferroptosis in breast cancer. Front Immunol 15:1455741","journal-title":"Front Immunol"},{"issue":"5","key":"2375_CR268","doi-asserted-by":"publisher","first-page":"659","DOI":"10.3390\/biom15050659","volume":"15","author":"D Lu","year":"2025","unstructured":"Lu D, Xia B, Feng T, Qi G, Ma Z (2025) The role of cancer organoids in ferroptosis, pyroptosis, and necroptosis: functions and clinical implications. Biomolecules 15(5):659","journal-title":"Biomolecules"},{"key":"2375_CR269","doi-asserted-by":"publisher","first-page":"1670328","DOI":"10.3389\/fcell.2025.1670328","volume":"13","author":"H Singh","year":"2025","unstructured":"Singh H, Mijakovic I, Singh P (2025) Advances in precision oncology using patient-derived organoids and functional biomaterials. Front Cell Dev Biol 13:1670328","journal-title":"Front Cell Dev Biol"},{"issue":"1","key":"2375_CR270","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1038\/s41420-025-02407-x","volume":"11","author":"J Wang","year":"2025","unstructured":"Wang J, Tao X, Zhu J, Dai Z, Du Y, Xie Y et al (2025) Tumor organoid-immune co-culture models: exploring a new perspective of tumor immunity. Cell Death Discov 11(1):195","journal-title":"Cell Death Discov"},{"key":"2375_CR271","doi-asserted-by":"crossref","unstructured":"Mei J, Jiang XY, Tian HX, Rong DC, Song JN, Wang L et al (2024) Anoikis in cell fate, physiopathology, and therapeutic interventions. MedComm 5(10):e718","DOI":"10.1002\/mco2.718"},{"issue":"6","key":"2375_CR272","doi-asserted-by":"publisher","first-page":"100792","DOI":"10.1016\/j.crmeth.2024.100792","volume":"4","author":"A Raffo-Romero","year":"2024","unstructured":"Raffo-Romero A, Ziane-Chaouche L, Salome-Desnoulez S, Hajjaji N, Fournier I, Salzet M et al (2024) A co-culture system of macrophages with breast cancer tumoroids to study cell interactions and therapeutic responses. Cell Rep Methods 4(6):100792","journal-title":"Cell Rep Methods"},{"issue":"1","key":"2375_CR273","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/s13058-015-0523-1","volume":"17","author":"JR Whittle","year":"2015","unstructured":"Whittle JR, Lewis MT, Lindeman GJ, Visvader JE (2015) Patient-derived xenograft models of breast cancer and their predictive power. Breast Cancer Res 17(1):17","journal-title":"Breast Cancer Res"},{"issue":"15","key":"2375_CR274","doi-asserted-by":"publisher","first-page":"2963","DOI":"10.1158\/0008-5472.CAN-15-0727","volume":"75","author":"JW Cassidy","year":"2015","unstructured":"Cassidy JW, Caldas C, Bruna A (2015) Maintaining tumor heterogeneity in patient-derived tumor xenografts. Cancer Res 75(15):2963\u20132968","journal-title":"Cancer Res"},{"issue":"5","key":"2375_CR275","doi-asserted-by":"publisher","first-page":"101520","DOI":"10.1016\/j.gendis.2025.101520","volume":"12","author":"M Liu","year":"2025","unstructured":"Liu M, Yang X (2025) Patient-derived xenograft models: current status, challenges, and innovations in cancer research. Genes Dis 12(5):101520","journal-title":"Genes Dis"},{"issue":"1","key":"2375_CR276","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1038\/s41392-023-01419-2","volume":"8","author":"Y Liu","year":"2023","unstructured":"Liu Y, Wu W, Cai C, Zhang H, Shen H, Han Y (2023) Patient-derived xenograft models in cancer therapy: technologies and applications. Signal Transduct Target Ther 8(1):160","journal-title":"Signal Transduct Target Ther"},{"issue":"8","key":"2375_CR277","first-page":"1","volume":"50","author":"Y Choi","year":"2018","unstructured":"Choi Y, Lee S, Kim K, Kim SH, Chung YJ, Lee C (2018) Studying cancer immunotherapy using patient-derived xenografts (PDXs) in humanized mice. Exp Mol Med 50(8):1\u20139","journal-title":"Exp Mol Med"},{"issue":"7","key":"2375_CR278","doi-asserted-by":"publisher","first-page":"e006921","DOI":"10.1136\/jitc-2023-006921","volume":"11","author":"M Chiorazzi","year":"2023","unstructured":"Chiorazzi M, Martinek J, Krasnick B, Zheng Y, Robbins KJ, Qu R et al (2023) Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment. J Immunother Cancer 11(7):e006921","journal-title":"J Immunother Cancer"},{"issue":"1","key":"2375_CR279","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1186\/s13058-021-01476-x","volume":"23","author":"SD Scherer","year":"2021","unstructured":"Scherer SD, Riggio AI, Haroun F, DeRose YS, Ekiz HA, Fujita M et al (2021) An immune-humanized patient-derived xenograft model of estrogen-independent, hormone receptor positive metastatic breast cancer. Breast Cancer Res 23(1):100","journal-title":"Breast Cancer Res"},{"key":"2375_CR280","doi-asserted-by":"publisher","first-page":"19","DOI":"10.3389\/fonc.2018.00019","volume":"8","author":"M Mattar","year":"2018","unstructured":"Mattar M, McCarthy CR, Kulick AR, Qeriqi B, Guzman S, de Stanchina E (2018) Establishing and maintaining an extensive library of patient-derived xenograft models. Front Oncol 8:19","journal-title":"Front Oncol"},{"key":"2375_CR281","doi-asserted-by":"publisher","first-page":"1690200","DOI":"10.3389\/fimmu.2025.1690200","volume":"16","author":"Q Jin","year":"2025","unstructured":"Jin Q, Chang Z, Chen K, Jiang N, Chen G, Lu Y (2025) Deep learning and multi-omics reveal programmed cell death-associated diagnostic signatures and prognostic biomarkers in gastric cancer. Front Immunol 16:1690200","journal-title":"Front Immunol"},{"key":"2375_CR282","doi-asserted-by":"publisher","first-page":"1779","DOI":"10.2147\/JMDH.S410301","volume":"16","author":"B Zhang","year":"2023","unstructured":"Zhang B, Shi H, Wang H (2023) Machine learning and AI in cancer prognosis, prediction, and treatment selection: a critical approach. J Multidiscip Healthc 16:1779\u20131791","journal-title":"J Multidiscip Healthc"},{"issue":"1","key":"2375_CR283","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1007\/s10238-025-01965-9","volume":"26","author":"CY Hsu","year":"2025","unstructured":"Hsu CY, Askar S, Alshkarchy SS, Nayak PP, Attabi KAL, Khan MA et al (2025) AI-driven multi-omics integration in precision oncology: bridging the data deluge to clinical decisions. Clin Exp Med 26(1):29","journal-title":"Clin Exp Med"},{"issue":"1","key":"2375_CR284","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1186\/s12911-025-02944-6","volume":"25","author":"R Alkhanbouli","year":"2025","unstructured":"Alkhanbouli R, Matar Abdulla Almadhaani H, Alhosani F, Simsekler MCE (2025) The role of explainable artificial intelligence in disease prediction: a systematic literature review and future research directions. BMC Med Inf Decis Mak 25(1):110","journal-title":"BMC Med Inf Decis Mak"},{"issue":"1","key":"2375_CR285","doi-asserted-by":"publisher","first-page":"e000255","DOI":"10.1136\/bmjonc-2023-000255","volume":"3","author":"S Macheka","year":"2024","unstructured":"Macheka S, Ng PY, Ginsburg O, Hope A, Sullivan R, Aggarwal A (2024) Prospective evaluation of artificial intelligence (AI) applications for use in cancer pathways following diagnosis: a systematic review. BMJ Oncol 3(1):e000255","journal-title":"BMJ Oncol"},{"key":"2375_CR286","doi-asserted-by":"crossref","unstructured":"Wang S, Guo S, Guo J, Du Q, Wu C, Wu Y et al (2024) Cell death pathways: molecular mechanisms and therapeutic targets for cancer. MedComm 5(9):e693","DOI":"10.1002\/mco2.693"},{"issue":"2","key":"2375_CR287","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1038\/s41419-023-05691-6","volume":"14","author":"K Ye","year":"2023","unstructured":"Ye K, Chen Z, Xu Y (2023) The double-edged functions of necroptosis. Cell Death Dis 14(2):163","journal-title":"Cell Death Dis"},{"issue":"10","key":"2375_CR288","doi-asserted-by":"publisher","first-page":"1688","DOI":"10.1016\/j.cmet.2023.09.004","volume":"35","author":"Y Zhao","year":"2023","unstructured":"Zhao Y, Liu Z, Liu G, Zhang Y, Liu S, Gan D et al (2023) Neutrophils resist ferroptosis and promote breast cancer metastasis through aconitate decarboxylase 1. Cell Metab 35(10):1688\u20131703 e10","journal-title":"Cell Metab"},{"issue":"1","key":"2375_CR289","first-page":"56","volume":"18","author":"X Wei","year":"2025","unstructured":"Wei X, Jiang Y, Chenwu F, Li Z, Wan J, Li Z et al (2025) Synergistic ferroptosis-immunotherapy nanoplatforms: multidimensional engineering for tumor microenvironment remodeling and therapeutic optimization. Nanomicro Lett 18(1):56","journal-title":"Nanomicro Lett"},{"issue":"19","key":"2375_CR290","doi-asserted-by":"publisher","first-page":"9686","DOI":"10.3390\/ijms26199686","volume":"26","author":"N Glibetic","year":"2025","unstructured":"Glibetic N, Weichhaus M (2025) Metabolic regulation of ferroptosis in breast cancer. Int J Mol Sci 26(19):9686","journal-title":"Int J Mol Sci"},{"key":"2375_CR291","doi-asserted-by":"publisher","first-page":"218077","DOI":"10.1016\/j.canlet.2025.218077","volume":"635","author":"Y Meng","year":"2025","unstructured":"Meng Y, Chen Q, Zhou Z, Li M (2025) Regulated cell death in cancer: mechanisms, crosstalk, and opportunities for therapy. Cancer Lett 635:218077","journal-title":"Cancer Lett"},{"issue":"14","key":"2375_CR292","doi-asserted-by":"publisher","first-page":"6658","DOI":"10.3390\/ijms26146658","volume":"26","author":"BK Sinha","year":"2025","unstructured":"Sinha BK (2025) Ferroptosis in toxicology: present and future. Int J Mol Sci 26(14):6658","journal-title":"Int J Mol Sci"},{"key":"2375_CR293","doi-asserted-by":"publisher","first-page":"127328","DOI":"10.1016\/j.envpol.2025.127328","volume":"387","author":"H Yang","year":"2025","unstructured":"Yang H, Niu S, Guo M, Liu C, Xue Y (2025) Toxic mechanisms of nanoparticle-induced ferroptosis and current research challenges: a critical review. Environ Pollut 387:127328","journal-title":"Environ Pollut"},{"key":"2375_CR294","doi-asserted-by":"publisher","first-page":"122655","DOI":"10.1016\/j.ijpharm.2023.122655","volume":"634","author":"W Li","year":"2023","unstructured":"Li W, Jiang Y, Lu J (2023) Nanotechnology-enabled immunogenic cell death for improved cancer immunotherapy. Int J Pharm 634:122655","journal-title":"Int J Pharm"},{"issue":"12","key":"2375_CR295","doi-asserted-by":"publisher","first-page":"1294","DOI":"10.1111\/1440-1681.13711","volume":"49","author":"B Thakur","year":"2022","unstructured":"Thakur B, Saha L, Bhatia A (2022) Relative refractoriness of breast cancer cells to tumour necrosis factor-alpha induced necroptosis. Clin Exp Pharmacol Physiol 49(12):1294\u20131306","journal-title":"Clin Exp Pharmacol Physiol"},{"issue":"1","key":"2375_CR296","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/j.cmet.2022.09.021","volume":"35","author":"F Yang","year":"2023","unstructured":"Yang F, Xiao Y, Ding JH, Jin X, Ma D, Li DQ et al (2023) Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy. Cell Metab 35(1):84\u2013100e8","journal-title":"Cell Metab"},{"issue":"1","key":"2375_CR297","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1038\/s41420-024-02121-0","volume":"10","author":"L Luobin","year":"2024","unstructured":"Luobin L, Wanxin H, Yingxin G, Qinzhou Z, Zefeng L, Danyang W et al (2024) Nanomedicine-induced programmed cell death in cancer therapy: mechanisms and perspectives. Cell Death Discov 10(1):386","journal-title":"Cell Death Discov"},{"key":"2375_CR298","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.jconrel.2019.02.007","volume":"299","author":"M Sharifi","year":"2019","unstructured":"Sharifi M, Hosseinali SH, Saboury AA, Szegezdi E, Falahati M (2019) Involvement of planned cell death of necroptosis in cancer treatment by nanomaterials: recent advances and future perspectives. J Control Release 299:121\u2013137","journal-title":"J Control Release"},{"key":"2375_CR299","doi-asserted-by":"publisher","first-page":"1083048","DOI":"10.3389\/fendo.2023.1083048","volume":"14","author":"K Andrade de Oliveira","year":"2023","unstructured":"Andrade de Oliveira K, Sengupta S, Yadav AK, Clarke R (2023) The complex nature of heterogeneity and its roles in breast cancer biology and therapeutic responsiveness. Front Endocrinol 14:1083048","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"1","key":"2375_CR300","doi-asserted-by":"publisher","first-page":"12728","DOI":"10.1038\/s41598-020-69026-7","volume":"10","author":"EA Mucino-Olmos","year":"2020","unstructured":"Mucino-Olmos EA, Vazquez-Jimenez A, Avila-Ponce de Leon U, Matadamas-Guzman M, Maldonado V, Lopez-Santaella T et al (2020) Unveiling functional heterogeneity in breast cancer multicellular tumor spheroids through single-cell RNA-seq. Sci Rep 10(1):12728","journal-title":"Sci Rep"},{"issue":"8","key":"2375_CR301","doi-asserted-by":"publisher","first-page":"806","DOI":"10.1016\/j.trecan.2025.04.004","volume":"11","author":"AM Finger","year":"2025","unstructured":"Finger AM, Hendley AM, Figueroa D, Gonzalez H, Weaver VM (2025) Tissue mechanics in tumor heterogeneity and aggression. Trends Cancer 11(8):806\u2013824","journal-title":"Trends Cancer"},{"issue":"8","key":"2375_CR302","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1097\/PAI.0000000000001139","volume":"31","author":"D Kashyap","year":"2023","unstructured":"Kashyap D, Bal A, Irinike S, Khare S, Bhattacharya S, Das A et al (2023) Heterogeneity of the tumor microenvironment across molecular subtypes of breast cancer. Appl Immunohistochem Mol Morphol 31(8):533\u2013543","journal-title":"Appl Immunohistochem Mol Morphol"},{"issue":"1","key":"2375_CR303","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1038\/s41698-021-00165-4","volume":"5","author":"A Li","year":"2021","unstructured":"Li A, Keck JM, Parmar S, Patterson J, Labrie M, Creason AL et al (2021) Characterizing advanced breast cancer heterogeneity and treatment resistance through serial biopsies and comprehensive analytics. NPJ Precis Oncol 5(1):28","journal-title":"NPJ Precis Oncol"},{"key":"2375_CR304","doi-asserted-by":"publisher","first-page":"100312","DOI":"10.1016\/j.jlb.2025.100312","volume":"9","author":"ML Schiavone","year":"2025","unstructured":"Schiavone ML, Scarpitta R, Ravera F, Bleve S, Reduzzi C, Di Cocco F et al (2025) Liquid biopsy in breast cancer: Redefining precision medicine. J Liq Biopsy 9:100312","journal-title":"J Liq Biopsy"},{"issue":"3","key":"2375_CR305","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1038\/sj.cgt.7700792","volume":"12","author":"L Zhang","year":"2005","unstructured":"Zhang L, Fang B (2005) Mechanisms of resistance to TRAIL-induced apoptosis in cancer. Cancer Gene Ther 12(3):228\u2013237","journal-title":"Cancer Gene Ther"},{"issue":"1","key":"2375_CR306","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1038\/s41420-024-02037-9","volume":"10","author":"S Wang","year":"2024","unstructured":"Wang S, Guo Q, Zhou L, Xia X (2024) Ferroptosis: a double-edged sword. Cell Death Discov 10(1):265","journal-title":"Cell Death Discov"},{"issue":"15","key":"2375_CR307","doi-asserted-by":"publisher","first-page":"2829","DOI":"10.1007\/s00018-016-2130-4","volume":"73","author":"S Matt","year":"2016","unstructured":"Matt S, Hofmann TG (2016) The DNA damage-induced cell death response: a roadmap to kill cancer cells. Cell Mol Life Sci 73(15):2829\u20132850","journal-title":"Cell Mol Life Sci"},{"key":"2375_CR308","doi-asserted-by":"publisher","first-page":"100916","DOI":"10.1016\/j.drup.2022.100916","volume":"66","author":"Y Wang","year":"2023","unstructured":"Wang Y, Wu X, Ren Z, Li Y, Zou W, Chen J et al (2023) Overcoming cancer chemotherapy resistance by the induction of ferroptosis. Drug Resist Updat 66:100916","journal-title":"Drug Resist Updat"},{"issue":"1","key":"2375_CR309","doi-asserted-by":"publisher","first-page":"138","DOI":"10.3390\/ijms27010138","volume":"27","author":"DP Intriago-Baldeon","year":"2025","unstructured":"Intriago-Baldeon DP, Perez-Coral ES, Armas Samaniego MI, Romero VI, Pozo Palacios JC, Bigoni-Ordonez GD (2025) Decoding breast cancer: emerging molecular biomarkers and novel therapeutic targets for precision medicine. Int J Mol Sci 27(1):138","journal-title":"Int J Mol Sci"},{"key":"2375_CR310","doi-asserted-by":"publisher","first-page":"1462339","DOI":"10.3389\/fcell.2024.1462339","volume":"12","author":"R Saxena","year":"2024","unstructured":"Saxena R, Welsh CM, He YW (2024) Targeting regulated cell death pathways in cancers for effective treatment: a comprehensive review. Front Cell Dev Biol 12:1462339","journal-title":"Front Cell Dev Biol"},{"issue":"1","key":"2375_CR311","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1515\/jtim-2025-0004","volume":"13","author":"Z Guo","year":"2025","unstructured":"Guo Z, Liu Y, Chen D, Sun Y, Li D, Meng Y et al (2025) Targeting regulated cell death: apoptosis, necroptosis, pyroptosis, ferroptosis, and cuproptosis in anticancer immunity. J Transl Int Med 13(1):10\u201332","journal-title":"J Transl Int Med"},{"issue":"8","key":"2375_CR312","doi-asserted-by":"publisher","first-page":"2204","DOI":"10.3390\/cancers15082204","volume":"15","author":"MA Subhan","year":"2023","unstructured":"Subhan MA, Parveen F, Shah H, Yalamarty SSK, Ataide JA, Torchilin VP (2023) Recent advances with precision medicine treatment for breast cancer including triple-negative sub-type. Cancers 15(8):2204","journal-title":"Cancers (Basel)"},{"issue":"10","key":"2375_CR313","first-page":"e2500028","volume":"10","author":"M Guo","year":"2026","unstructured":"Guo M, Passalacqua E, Bao E, Miao B, Butte A, Zack T (2026) Exploring the past and current landscape of biomarker-driven clinical trials through large language models. JCO Clin Cancer Inf 10(10):e2500028","journal-title":"JCO Clin Cancer Inf"}],"container-title":["Apoptosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10495-026-02375-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10495-026-02375-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10495-026-02375-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T18:03:12Z","timestamp":1784052192000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10495-026-02375-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,16]]},"references-count":313,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["2375"],"URL":"https:\/\/doi.org\/10.1007\/s10495-026-02375-2","relation":{},"ISSN":["1360-8185","1573-675X"],"issn-type":[{"value":"1360-8185","type":"print"},{"value":"1573-675X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,16]]},"assertion":[{"value":"19 March 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 May 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 June 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"170"}}