{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T03:21:44Z","timestamp":1790997704872,"version":"4.1.0"},"reference-count":155,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T00:00:00Z","timestamp":1787184000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T00:00:00Z","timestamp":1787184000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82370856"],"award-info":[{"award-number":["82370856"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Apoptosis"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1007\/s10495-026-02428-6","type":"journal-article","created":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T12:08:15Z","timestamp":1787227695000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Programmed cell death in kidney disease: integrated crosstalk among ferroptosis, pyroptosis, apoptosis, and cuproptosis"],"prefix":"10.1007","volume":"31","author":[{"given":"Jiajun","family":"Sang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhentao","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengxia","family":"Kan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7775-2823","authenticated-orcid":false,"given":"Xiaodong","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kexin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,8,20]]},"reference":[{"issue":"5","key":"2428_CR1","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1038\/s41418-023-01153-w","volume":"30","author":"I Vitale","year":"2023","unstructured":"Vitale I, Pietrocola F, Guilbaud E et al (2023) Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell Death Differ 30(5):1097\u20131154. https:\/\/doi.org\/10.1038\/s41418-023-01153-w","journal-title":"Cell Death Differ"},{"key":"2428_CR2","doi-asserted-by":"publisher","first-page":"1513895","DOI":"10.3389\/fendo.2025.1513895","volume":"16","author":"L Wang","year":"2025","unstructured":"Wang L, Ding S, Hu Y et al (2025) Targeting programmed cell death pathways: emerging therapeutic strategies for diabetic kidney disease. Front Endocrinol (Lausanne) 16:1513895. https:\/\/doi.org\/10.3389\/fendo.2025.1513895","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"3\u20134","key":"2428_CR3","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1007\/s10495-024-02072-y","volume":"30","author":"Y Hou","year":"2025","unstructured":"Hou Y, Feng Q, Wei C et al (2025) Emerging role of PANoptosis in kidney diseases: molecular mechanisms and therapeutic opportunities. Apoptosis 30(3\u20134):579\u2013596. https:\/\/doi.org\/10.1007\/s10495-024-02072-y","journal-title":"Apoptosis"},{"issue":"6586","key":"2428_CR4","doi-asserted-by":"publisher","first-page":"1254","DOI":"10.1126\/science.abf0529","volume":"375","author":"P Tsvetkov","year":"2022","unstructured":"Tsvetkov P, Coy S, Petrova B et al (2022) Copper induces cell death by targeting lipoylated TCA cycle proteins. Science 375(6586):1254\u20131261. https:\/\/doi.org\/10.1126\/science.abf0529","journal-title":"Science"},{"issue":"4","key":"2428_CR5","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1038\/s41580-020-00324-8","volume":"22","author":"X Jiang","year":"2021","unstructured":"Jiang X, Stockwell BR, Conrad M (2021) Ferroptosis: mechanisms, biology and role in disease. Nat Rev Mol Cell Biol 22(4):266\u2013282. https:\/\/doi.org\/10.1038\/s41580-020-00324-8","journal-title":"Nat Rev Mol Cell Biol"},{"key":"2428_CR6","doi-asserted-by":"publisher","unstructured":"Jiang L, Zhao L, Liu Y et al (2025) PANoptosis: A novel therapeutic target in kidney disease (Review). Int J Mol Med 56(6). https:\/\/doi.org\/10.3892\/ijmm.2025.5648","DOI":"10.3892\/ijmm.2025.5648"},{"issue":"45","key":"2428_CR7","doi-asserted-by":"publisher","first-page":"eadp7160","DOI":"10.1126\/sciadv.adp7160","volume":"10","author":"G Hou","year":"2024","unstructured":"Hou G, Chen Y, Lei H et al (2024) Bimetallic peroxide nanoparticles induce PANoptosis by disrupting ion homeostasis for enhanced immunotherapy. Sci Adv 10(45):eadp7160. https:\/\/doi.org\/10.1126\/sciadv.adp7160","journal-title":"Sci Adv"},{"issue":"2","key":"2428_CR8","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/j.kint.2024.10.026","volume":"107","author":"Z Lv","year":"2025","unstructured":"Lv Z, Hu J, Su H et al (2025) TRAIL induces podocyte PANoptosis via death receptor 5 in diabetic kidney disease. Kidney Int 107(2):317\u2013331. https:\/\/doi.org\/10.1016\/j.kint.2024.10.026","journal-title":"Kidney Int"},{"issue":"5","key":"2428_CR9","doi-asserted-by":"publisher","first-page":"1580","DOI":"10.3390\/nu13051580","volume":"13","author":"LS Gewin","year":"2021","unstructured":"Gewin LS (2021) Sugar or Fat? Renal Tubular Metabolism Reviewed in Health and Disease. Nutrients 13(5):1580. https:\/\/doi.org\/10.3390\/nu13051580","journal-title":"Nutrients"},{"issue":"1","key":"2428_CR10","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1186\/s40001-025-02861-4","volume":"30","author":"K Guan","year":"2025","unstructured":"Guan K, Zhang Y, Guo S, Ning X, Sun S (2025) DPP8 and DPP9 promote tubular epithelial cell ferroptosis in acute kidney injury. Eur J Med Res 30(1):630. https:\/\/doi.org\/10.1186\/s40001-025-02861-4","journal-title":"Eur J Med Res"},{"issue":"1","key":"2428_CR11","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.kint.2024.04.011","volume":"106","author":"Y Feng","year":"2024","unstructured":"Feng Y, Sun Z, Fu J et al (2024) Podocyte-derived soluble RARRES1 drives kidney disease progression through direct podocyte and proximal tubular injury. Kidney Int 106(1):50\u201366. https:\/\/doi.org\/10.1016\/j.kint.2024.04.011","journal-title":"Kidney Int"},{"issue":"5","key":"2428_CR12","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1080\/01480545.2024.2434900","volume":"48","author":"X Ma","year":"2025","unstructured":"Ma X, Pang L, Shi F, Guan B (2025) Ginsenoside Rk1 exerts protective effects of LPS-induced podocyte apoptosis and inflammation by inactivating JAK2\/STAT3 and NF-\u03baB pathways. Drug Chem Toxicol 48(5):1057\u20131066. https:\/\/doi.org\/10.1080\/01480545.2024.2434900","journal-title":"Drug Chem Toxicol"},{"issue":"1","key":"2428_CR13","doi-asserted-by":"publisher","first-page":"10430","DOI":"10.1038\/s41467-025-65978-4","volume":"16","author":"J Zhou","year":"2025","unstructured":"Zhou J, Wang S, Lou J et al (2025) FGF4-FGFR1 signaling promotes podocyte survival and glomerular function to ameliorate diabetic kidney disease in male mice. Nat Commun 16(1):10430. https:\/\/doi.org\/10.1038\/s41467-025-65978-4","journal-title":"Nat Commun"},{"key":"2428_CR14","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.freeradbiomed.2022.01.012","volume":"180","author":"GH Chen","year":"2022","unstructured":"Chen GH, Song CC, Pantopoulos K, Wei XL, Zheng H, Luo Z (2022) Mitochondrial oxidative stress mediated Fe-induced ferroptosis via the NRF2-ARE pathway. Free Radic Biol Med 180:95\u2013107. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2022.01.012","journal-title":"Free Radic Biol Med"},{"issue":"11","key":"2428_CR15","doi-asserted-by":"publisher","first-page":"2523","DOI":"10.1016\/j.immuni.2023.10.004","volume":"56","author":"R Miao","year":"2023","unstructured":"Miao R, Jiang C, Chang WY et al (2023) Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis. Immunity 56(11):2523\u20132541e8. https:\/\/doi.org\/10.1016\/j.immuni.2023.10.004","journal-title":"Immunity"},{"issue":"2","key":"2428_CR16","doi-asserted-by":"publisher","first-page":"C254","DOI":"10.1152\/ajpcell.00497.2023","volume":"327","author":"H Li","year":"2024","unstructured":"Li H, Fu Y, Xu Y et al (2024) Cuproptosis associated cytoskeletal destruction contributes to podocyte injury in chronic kidney disease. Am J Physiol Cell Physiol 327(2):C254\u2013C269. https:\/\/doi.org\/10.1152\/ajpcell.00497.2023","journal-title":"Am J Physiol Cell Physiol"},{"key":"2428_CR17","doi-asserted-by":"publisher","first-page":"1352032","DOI":"10.3389\/fmolb.2024.1352032","volume":"11","author":"S Punchai","year":"2024","unstructured":"Punchai S, Chaiyagot N, Artkaew N et al (2024) Iron-induced kidney cell damage: insights into molecular mechanisms and potential diagnostic significance of urinary FTL. Front Mol Biosci 11:1352032. https:\/\/doi.org\/10.3389\/fmolb.2024.1352032","journal-title":"Front Mol Biosci"},{"issue":"1","key":"2428_CR18","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1038\/nchembio.2239","volume":"13","author":"S Doll","year":"2017","unstructured":"Doll S, Proneth B, Tyurina YY et al (2017) ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition. Nat Chem Biol 13(1):91\u201398. https:\/\/doi.org\/10.1038\/nchembio.2239","journal-title":"Nat Chem Biol"},{"issue":"7\u20139","key":"2428_CR19","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1089\/ars.2023.0237","volume":"39","author":"J Cui","year":"2023","unstructured":"Cui J, Wang Y, Tian X et al (2023) LPCAT3 Is Transcriptionally Regulated by YAP\/ZEB\/EP300 and Collaborates with ACSL4 and YAP to Determine Ferroptosis Sensitivity. Antioxid Redox Signal 39(7\u20139):491\u2013511. https:\/\/doi.org\/10.1089\/ars.2023.0237","journal-title":"Antioxid Redox Signal"},{"issue":"7784","key":"2428_CR20","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1038\/s41586-019-1705-2","volume":"575","author":"K Bersuker","year":"2019","unstructured":"Bersuker K, Hendricks JM, Li Z et al (2019) The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis. Nature 575(7784):688\u2013692. https:\/\/doi.org\/10.1038\/s41586-019-1705-2","journal-title":"Nature"},{"issue":"11","key":"2428_CR21","doi-asserted-by":"publisher","first-page":"1754","DOI":"10.1093\/ndt\/gfae097","volume":"39","author":"T Seibt","year":"2024","unstructured":"Seibt T, Wahida A, Hoeft K et al (2024) The biology of ferroptosis in kidney disease. Nephrol Dial Transpl 39(11):1754\u20131761. https:\/\/doi.org\/10.1093\/ndt\/gfae097","journal-title":"Nephrol Dial Transpl"},{"issue":"5","key":"2428_CR22","doi-asserted-by":"publisher","first-page":"1060","DOI":"10.1016\/j.cell.2012.03.042","volume":"149","author":"SJ Dixon","year":"2012","unstructured":"Dixon SJ, Lemberg KM, Lamprecht MR et al (2012) Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell 149(5):1060\u20131072. https:\/\/doi.org\/10.1016\/j.cell.2012.03.042","journal-title":"Cell"},{"issue":"5","key":"2428_CR23","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1038\/s41419-024-06712-8","volume":"15","author":"Y Chen","year":"2024","unstructured":"Chen Y, Li X, Yang M, Liu SB (2024) Research progress on morphology and mechanism of programmed cell death. Cell Death Dis 15(5):327. https:\/\/doi.org\/10.1038\/s41419-024-06712-8","journal-title":"Cell Death Dis"},{"key":"2428_CR24","doi-asserted-by":"publisher","first-page":"1531577","DOI":"10.3389\/fimmu.2025.1531577","volume":"16","author":"W Wang","year":"2025","unstructured":"Wang W, Chen J, Zhan L et al (2025) Iron and ferroptosis in kidney disease: molecular and metabolic mechanisms. Front Immunol 16:1531577. https:\/\/doi.org\/10.3389\/fimmu.2025.1531577","journal-title":"Front Immunol"},{"issue":"7575","key":"2428_CR25","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1038\/nature15514","volume":"526","author":"J Shi","year":"2015","unstructured":"Shi J, Zhao Y, Wang K et al (2015) Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death. Nature 526(7575):660\u2013665. https:\/\/doi.org\/10.1038\/nature15514","journal-title":"Nature"},{"issue":"1","key":"2428_CR26","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1038\/s41419-021-04480-3","volume":"13","author":"BY Nam","year":"2022","unstructured":"Nam BY, Jhee JH, Park J et al (2022) PGC-1\u03b1 inhibits the NLRP3 inflammasome via preserving mitochondrial viability to protect kidney fibrosis. Cell Death Dis 13(1):31. https:\/\/doi.org\/10.1038\/s41419-021-04480-3","journal-title":"Cell Death Dis"},{"key":"2428_CR27","doi-asserted-by":"publisher","first-page":"1676152","DOI":"10.1155\/2021\/1676152","volume":"2021","author":"P Lv","year":"2021","unstructured":"Lv P, Liu H, Ye T et al (2021) XIST Inhibition Attenuates Calcium Oxalate Nephrocalcinosis-Induced Renal Inflammation and Oxidative Injury via the miR-223\/NLRP3 Pathway. Oxid Med Cell Longev 2021:1676152. https:\/\/doi.org\/10.1155\/2021\/1676152","journal-title":"Oxid Med Cell Longev"},{"issue":"3","key":"2428_CR28","doi-asserted-by":"publisher","first-page":"7528","DOI":"10.1080\/21655979.2022.2047394","volume":"13","author":"C Bai","year":"2022","unstructured":"Bai C, Zhu Y, Dong Q, Zhang Y (2022) Chronic intermittent hypoxia induces the pyroptosis of renal tubular epithelial cells by activating the NLRP3 inflammasome. Bioengineered 13(3):7528\u20137540. https:\/\/doi.org\/10.1080\/21655979.2022.2047394","journal-title":"Bioengineered"},{"issue":"3","key":"2428_CR29","doi-asserted-by":"publisher","first-page":"e2510274123","DOI":"10.1073\/pnas.2510274123","volume":"123","author":"R Ricci-Azevedo","year":"2026","unstructured":"Ricci-Azevedo R, Sarkar B, Shivcharan S et al (2026) Redefining Shiga toxin-induced human cell death as NLRP1- and gasdermin E-mediated pyroptosis. Proc Natl Acad Sci U S A 123(3):e2510274123. https:\/\/doi.org\/10.1073\/pnas.2510274123","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"12","key":"2428_CR30","doi-asserted-by":"publisher","first-page":"2487","DOI":"10.1038\/s41418-022-01033-9","volume":"29","author":"C Baatarjav","year":"2022","unstructured":"Baatarjav C, Komada T, Karasawa T et al (2022) dsDNA-induced AIM2 pyroptosis halts aberrant inflammation during rhabdomyolysis-induced acute kidney injury. Cell Death Differ 29(12):2487\u20132502. https:\/\/doi.org\/10.1038\/s41418-022-01033-9","journal-title":"Cell Death Differ"},{"issue":"1","key":"2428_CR31","doi-asserted-by":"publisher","first-page":"1164","DOI":"10.1038\/s41467-024-45396-8","volume":"15","author":"X Yu","year":"2024","unstructured":"Yu X, Matico RE, Miller R et al (2024) Structural basis for the oligomerization-facilitated NLRP3 activation. Nat Commun 15(1):1164. https:\/\/doi.org\/10.1038\/s41467-024-45396-8","journal-title":"Nat Commun"},{"issue":"14","key":"2428_CR32","doi-asserted-by":"publisher","first-page":"e98321","DOI":"10.15252\/embj.201798321","volume":"37","author":"E Mulvihill","year":"2018","unstructured":"Mulvihill E, Sborgi L, Mari SA, Pfreundschuh M, Hiller S, M\u00fcller DJ (2018) Mechanism of membrane pore formation by human gasdermin-D. EMBO J 37(14):e98321. https:\/\/doi.org\/10.15252\/embj.201798321","journal-title":"EMBO J"},{"issue":"8","key":"2428_CR33","doi-asserted-by":"publisher","first-page":"2333","DOI":"10.1038\/s41418-021-00755-6","volume":"28","author":"Y Li","year":"2021","unstructured":"Li Y, Yuan Y, Huang ZX et al (2021) GSDME-mediated pyroptosis promotes inflammation and fibrosis in obstructive nephropathy. Cell Death Differ 28(8):2333\u20132350. https:\/\/doi.org\/10.1038\/s41418-021-00755-6","journal-title":"Cell Death Differ"},{"issue":"5","key":"2428_CR34","doi-asserted-by":"publisher","first-page":"3050","DOI":"10.1007\/s10753-025-02249-w","volume":"48","author":"Y Guo","year":"2025","unstructured":"Guo Y, Min J, Chang B, Chen Z, Chen W (2025) Exploring the Role of TRAF6-TAK1 Pathway in Podocyte Pyroptosis and Its Implications for Primary Membranous Nephropathy Therapy. Inflammation 48(5):3050\u20133065. https:\/\/doi.org\/10.1007\/s10753-025-02249-w","journal-title":"Inflammation"},{"key":"2428_CR35","doi-asserted-by":"publisher","first-page":"1289","DOI":"10.2147\/DMSO.S450695","volume":"17","author":"X Li","year":"2024","unstructured":"Li X, Gao L, Li X, Xia J, Pan Y, Bai C (2024) Autophagy, Pyroptosis and Ferroptosis are Rising Stars in the Pathogenesis of Diabetic Nephropathy. Diabetes Metab Syndr Obes 17:1289\u20131299. https:\/\/doi.org\/10.2147\/DMSO.S450695","journal-title":"Diabetes Metab Syndr Obes"},{"key":"2428_CR36","doi-asserted-by":"publisher","first-page":"8772009","DOI":"10.1155\/2024\/8772009","volume":"2024","author":"Z Zhang","year":"2024","unstructured":"Zhang Z, Bi Y, Zhou F et al (2024) Huajuxiaoji Formula Alleviates Phenyl Sulfate-Induced Diabetic Kidney Disease by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis. J Diabetes Res 2024:8772009. https:\/\/doi.org\/10.1155\/2024\/8772009","journal-title":"J Diabetes Res"},{"issue":"1","key":"2428_CR37","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1016\/j.molcel.2023.11.040","volume":"84","author":"Y Ai","year":"2024","unstructured":"Ai Y, Meng Y, Yan B, Zhou Q, Wang X (2024) The biochemical pathways of apoptotic, necroptotic, pyroptotic, and ferroptotic cell death. Mol Cell 84(1):170\u2013179. https:\/\/doi.org\/10.1016\/j.molcel.2023.11.040","journal-title":"Mol Cell"},{"issue":"8","key":"2428_CR38","doi-asserted-by":"publisher","first-page":"1344","DOI":"10.1093\/ndt\/gfae014","volume":"39","author":"Z Chen","year":"2024","unstructured":"Chen Z, Chen C, Lai K et al (2024) GSDMD and GSDME synergy in the transition of acute kidney injury to chronic kidney disease. Nephrol Dial Transpl 39(8):1344\u20131359. https:\/\/doi.org\/10.1093\/ndt\/gfae014","journal-title":"Nephrol Dial Transpl"},{"issue":"1","key":"2428_CR39","doi-asserted-by":"publisher","first-page":"F4","DOI":"10.1152\/ajprenal.00275.2023","volume":"327","author":"MR Noh","year":"2024","unstructured":"Noh MR, Padanilam BJ (2024) Cell death induced by acute renal injury: a perspective on the contributions of accidental and programmed cell death. Am J Physiol Ren Physiol 327(1):F4\u2013F20. https:\/\/doi.org\/10.1152\/ajprenal.00275.2023","journal-title":"Am J Physiol Ren Physiol"},{"issue":"6754","key":"2428_CR40","doi-asserted-by":"publisher","first-page":"eadv4314","DOI":"10.1126\/science.adv4314","volume":"388","author":"Y Zhang","year":"2025","unstructured":"Zhang Y, Tian L, Huang G et al (2025) Structural basis of BAX pore formation. Science 388(6754):eadv4314. https:\/\/doi.org\/10.1126\/science.adv4314","journal-title":"Science"},{"issue":"9","key":"2428_CR41","doi-asserted-by":"publisher","first-page":"3896","DOI":"10.1038\/s44319-024-00206-6","volume":"25","author":"TB Beigl","year":"2024","unstructured":"Beigl TB, Paul A, Fellmeth TP et al (2024) BCL-2 and BOK regulate apoptosis by interaction of their C-terminal transmembrane domains. EMBO Rep 25(9):3896\u20133924. https:\/\/doi.org\/10.1038\/s44319-024-00206-6","journal-title":"EMBO Rep"},{"issue":"23","key":"2428_CR42","doi-asserted-by":"publisher","first-page":"e2504819122","DOI":"10.1073\/pnas.2504819122","volume":"122","author":"E Fosuah","year":"2025","unstructured":"Fosuah E, Shen Z, Xie J, Wang C, Lin Q, Fu TM (2025) Assembly and activation of the death-inducing signaling complex. Proc Natl Acad Sci U S A 122(23):e2504819122. https:\/\/doi.org\/10.1073\/pnas.2504819122","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"34","key":"2428_CR43","doi-asserted-by":"publisher","first-page":"e2425802122","DOI":"10.1073\/pnas.2425802122","volume":"122","author":"Y Chen","year":"2025","unstructured":"Chen Y, Huynh VT, Lai L et al (2025) FADDDED filaments coordinate complex IIa assembly during TNF-induced apoptosis. Proc Natl Acad Sci U S A 122(34):e2425802122. https:\/\/doi.org\/10.1073\/pnas.2425802122","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"21","key":"2428_CR44","doi-asserted-by":"publisher","first-page":"2235","DOI":"10.1016\/j.devcel.2023.08.009","volume":"58","author":"K Duszyc","year":"2023","unstructured":"Duszyc K, von Pein JB, Ramnath D et al (2023) Apical extrusion prevents apoptosis from activating an acute inflammatory program in epithelia. Dev Cell 58(21):2235\u20132248e6. https:\/\/doi.org\/10.1016\/j.devcel.2023.08.009","journal-title":"Dev Cell"},{"issue":"6","key":"2428_CR45","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1038\/s41419-021-03751-3","volume":"12","author":"T Zheng","year":"2021","unstructured":"Zheng T, Tan Y, Qiu J et al (2021) Alternative polyadenylation trans-factor FIP1 exacerbates UUO\/IRI-induced kidney injury and contributes to AKI-CKD transition via ROS-NLRP3 axis. Cell Death Dis 12(6):512. https:\/\/doi.org\/10.1038\/s41419-021-03751-3","journal-title":"Cell Death Dis"},{"key":"2428_CR46","doi-asserted-by":"publisher","first-page":"1478697","DOI":"10.3389\/fmed.2024.1478697","volume":"11","author":"M Cortinovis","year":"2024","unstructured":"Cortinovis M, Perico N, Remuzzi G (2024) Tubulointerstitial injury in proteinuric chronic kidney diseases. Front Med (Lausanne) 11:1478697. https:\/\/doi.org\/10.3389\/fmed.2024.1478697","journal-title":"Front Med (Lausanne)"},{"key":"2428_CR47","doi-asserted-by":"publisher","unstructured":"Li L, Liao J, Yuan Q et al (2021) Fibrillin-1-enriched microenvironment drives endothelial injury and vascular rarefaction in chronic kidney disease. Sci Adv 7(5). https:\/\/doi.org\/10.1126\/sciadv.abc7170","DOI":"10.1126\/sciadv.abc7170"},{"issue":"1","key":"2428_CR48","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1007\/s00018-024-05358-1","volume":"81","author":"S Zhu","year":"2024","unstructured":"Zhu S, Niu Y, Zhou W et al (2024) Mitochondrial copper overload promotes renal fibrosis via inhibiting pyruvate dehydrogenase activity. Cell Mol Life Sci 81(1):340. https:\/\/doi.org\/10.1007\/s00018-024-05358-1","journal-title":"Cell Mol Life Sci"},{"key":"2428_CR49","doi-asserted-by":"publisher","first-page":"1700004","DOI":"10.3389\/fimmu.2025.1700004","volume":"16","author":"Y Luo","year":"2025","unstructured":"Luo Y, Long M, Wu X, Zeng L (2025) Targeting ferroptosis: novel therapeutic approaches and intervention strategies for kidney diseases. Front Immunol 16:1700004. https:\/\/doi.org\/10.3389\/fimmu.2025.1700004","journal-title":"Front Immunol"},{"key":"2428_CR50","doi-asserted-by":"publisher","first-page":"927641","DOI":"10.3389\/fphar.2022.927641","volume":"13","author":"Y Liang","year":"2022","unstructured":"Liang Y, Liu Z, Qu L et al (2022) Inhibition of the IRE1\/JNK pathway in renal tubular epithelial cells attenuates ferroptosis in acute kidney injury. Front Pharmacol 13:927641. https:\/\/doi.org\/10.3389\/fphar.2022.927641","journal-title":"Front Pharmacol"},{"key":"2428_CR51","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1016\/j.freeradbiomed.2025.05.390","volume":"236","author":"Z Qian","year":"2025","unstructured":"Qian Z, Zhang X, Huang J et al (2025) Glucose deprivation-restoration induces labile iron overload and ferroptosis in renal tubules through V-ATPase-mTOR axis-mediated ferritinophagy and iron release by TPC2. Free Radic Biol Med 236:204\u2013219. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2025.05.390","journal-title":"Free Radic Biol Med"},{"issue":"48","key":"2428_CR52","doi-asserted-by":"publisher","first-page":"e2408945","DOI":"10.1002\/advs.202408945","volume":"11","author":"C Duan","year":"2024","unstructured":"Duan C, Li B, Liu H et al (2024) Sirtuin1 Suppresses Calcium Oxalate Nephropathy via Inhibition of Renal Proximal Tubular Cell Ferroptosis Through PGC-1\u03b1-mediated Transcriptional Coactivation. Adv Sci (Weinh) 11(48):e2408945. https:\/\/doi.org\/10.1002\/advs.202408945","journal-title":"Adv Sci (Weinh)"},{"issue":"5","key":"2428_CR53","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1038\/s41581-023-00689-x","volume":"19","author":"H Bay\u0131r","year":"2023","unstructured":"Bay\u0131r H, Dixon SJ, Tyurina YY, Kellum JA, Kagan VE (2023) Ferroptotic mechanisms and therapeutic targeting of iron metabolism and lipid peroxidation in the kidney. Nat Rev Nephrol 19(5):315\u2013336. https:\/\/doi.org\/10.1038\/s41581-023-00689-x","journal-title":"Nat Rev Nephrol"},{"issue":"1","key":"2428_CR54","doi-asserted-by":"publisher","first-page":"2548613","DOI":"10.1080\/0886022X.2025.2548613","volume":"47","author":"FY Tian","year":"2025","unstructured":"Tian FY, Liu K, Tang ZY et al (2025) Glycyrrhizin alleviates contrast-induced acute kidney injury via inhibiting HMGB1-mediated renal tubular epithelial cells ferroptosis. Ren Fail 47(1):2548613. https:\/\/doi.org\/10.1080\/0886022X.2025.2548613","journal-title":"Ren Fail"},{"issue":"43","key":"2428_CR55","doi-asserted-by":"publisher","first-page":"e2404753","DOI":"10.1002\/advs.202404753","volume":"11","author":"NN Liang","year":"2024","unstructured":"Liang NN, Guo YY, Zhang XY et al (2024) Mitochondrial Dysfunction-Evoked DHODH Acetylation is Involved in Renal Cell Ferroptosis during Cisplatin-Induced Acute Kidney Injury. Adv Sci (Weinh) 11(43):e2404753. https:\/\/doi.org\/10.1002\/advs.202404753","journal-title":"Adv Sci (Weinh)"},{"issue":"4","key":"2428_CR56","doi-asserted-by":"publisher","first-page":"1192","DOI":"10.7150\/ijbs.80775","volume":"19","author":"Q Lin","year":"2023","unstructured":"Lin Q, Li S, Jin H et al (2023) Mitophagy alleviates cisplatin-induced renal tubular epithelial cell ferroptosis through ROS\/HO-1\/GPX4 axis. Int J Biol Sci 19(4):1192\u20131210. https:\/\/doi.org\/10.7150\/ijbs.80775","journal-title":"Int J Biol Sci"},{"key":"2428_CR57","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.freeradbiomed.2024.07.019","volume":"223","author":"B Dai","year":"2024","unstructured":"Dai B, Liu X, Du M et al (2024) LATS1 inhibitor and zinc supplement synergistically ameliorates contrast-induced acute kidney injury: Induction of Metallothionein-1 and suppression of tubular ferroptosis. Free Radic Biol Med 223:42\u201352. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2024.07.019","journal-title":"Free Radic Biol Med"},{"key":"2428_CR58","doi-asserted-by":"publisher","unstructured":"Wu T, Wu X, Cai J et al (2026) STING1 exacerbates iodinated contrast-induced acute kidney injury by promoting ferroptosis through chaperone-mediated autophagic degradation of FTH1. Autophagy 1\u201316. https:\/\/doi.org\/10.1080\/15548627.2026.2626388","DOI":"10.1080\/15548627.2026.2626388"},{"issue":"3","key":"2428_CR59","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1159\/000538106","volume":"10","author":"Z Han","year":"2024","unstructured":"Han Z, Luo Y, Chen H et al (2024) A Deep Insight into Ferroptosis in Renal Disease: Facts and Perspectives. Kidney Dis (Basel) 10(3):224\u2013236. https:\/\/doi.org\/10.1159\/000538106","journal-title":"Kidney Dis (Basel)"},{"issue":"1","key":"2428_CR60","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1038\/s41420-022-00931-8","volume":"8","author":"J Wang","year":"2022","unstructured":"Wang J, Wang Y, Liu Y et al (2022) Ferroptosis, a new target for treatment of renal injury and fibrosis in a 5\/6 nephrectomy-induced CKD rat model. Cell Death Discov 8(1):127. https:\/\/doi.org\/10.1038\/s41420-022-00931-8","journal-title":"Cell Death Discov"},{"key":"2428_CR61","doi-asserted-by":"publisher","first-page":"102939","DOI":"10.1016\/j.redox.2023.102939","volume":"68","author":"L Zhang","year":"2023","unstructured":"Zhang L, Chen F, Dong J et al (2023) HDAC3 aberration-incurred GPX4 suppression drives renal ferroptosis and AKI-CKD progression. Redox Biol 68:102939. https:\/\/doi.org\/10.1016\/j.redox.2023.102939","journal-title":"Redox Biol"},{"issue":"2","key":"2428_CR62","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1038\/s41419-021-03452-x","volume":"12","author":"S Kim","year":"2021","unstructured":"Kim S, Kang SW, Joo J et al (2021) Characterization of ferroptosis in kidney tubular cell death under diabetic conditions. Cell Death Dis 12(2):160. https:\/\/doi.org\/10.1038\/s41419-021-03452-x","journal-title":"Cell Death Dis"},{"issue":"3","key":"2428_CR63","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1007\/s00125-025-06612-2","volume":"69","author":"S Matsui","year":"2026","unstructured":"Matsui S, Yamamoto T, Takabatake Y et al (2026) Defective autophagy and AMPK inactivation drive ferroptosis in diabetic kidney disease. Diabetologia 69(3):815\u2013832. https:\/\/doi.org\/10.1007\/s00125-025-06612-2","journal-title":"Diabetologia"},{"issue":"1","key":"2428_CR64","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1038\/s41420-024-02179-w","volume":"10","author":"Z Xia","year":"2024","unstructured":"Xia Z, Wei Z, Li X et al (2024) C\/EBP\u03b1-mediated ACSL4-dependent ferroptosis exacerbates tubular injury in diabetic kidney disease. Cell Death Discov 10(1):448. https:\/\/doi.org\/10.1038\/s41420-024-02179-w","journal-title":"Cell Death Discov"},{"issue":"1","key":"2428_CR65","doi-asserted-by":"publisher","first-page":"2576881","DOI":"10.1080\/08916934.2025.2576881","volume":"58","author":"J Qin","year":"2025","unstructured":"Qin J, Chen Z, Ye M, Liang L, Ding X (2025) High glucose promotes O-GlcNAcylation of ACSL4 to induce ferroptosis of renal tubular epithelial cell. Autoimmunity 58(1):2576881. https:\/\/doi.org\/10.1080\/08916934.2025.2576881","journal-title":"Autoimmunity"},{"issue":"9\u201310","key":"2428_CR66","doi-asserted-by":"publisher","first-page":"1780","DOI":"10.1007\/s10495-024-01955-4","volume":"29","author":"H Chen","year":"2024","unstructured":"Chen H, Zhang Y, Miao Y et al (2024) Vitamin D inhibits ferroptosis and mitigates the kidney injury of prediabetic mice by activating the Klotho\/p53 signaling pathway. Apoptosis 29(9\u201310):1780\u20131792. https:\/\/doi.org\/10.1007\/s10495-024-01955-4","journal-title":"Apoptosis"},{"key":"2428_CR67","doi-asserted-by":"publisher","first-page":"6699","DOI":"10.2147\/DDDT.S526554","volume":"19","author":"Y Zhou","year":"2025","unstructured":"Zhou Y, Lou C, Xu X, Feng B, Fan X, Wang X (2025) Ursolic Acid Ameliorates Diabetic Nephropathy by Inhibiting JAK2\/STAT3-Driven Ferroptosis: Mechanistic Insights from Network Pharmacology and Experimental Validation. Drug Des Devel Ther 19:6699\u20136717. https:\/\/doi.org\/10.2147\/DDDT.S526554","journal-title":"Drug Des Devel Ther"},{"key":"2428_CR68","doi-asserted-by":"publisher","first-page":"1499555","DOI":"10.3389\/fendo.2025.1499555","volume":"16","author":"R Shen","year":"2025","unstructured":"Shen R, Yu X, Shi C, Fang Y, Dai C, Zhou Y (2025) ACSL4 predicts rapid kidney function decline in patients with diabetic kidney disease. Front Endocrinol (Lausanne) 16:1499555. https:\/\/doi.org\/10.3389\/fendo.2025.1499555","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"7","key":"2428_CR69","doi-asserted-by":"publisher","first-page":"e71721","DOI":"10.1096\/fj.202504648R","volume":"40","author":"X Zhou","year":"2026","unstructured":"Zhou X, Zhang R, Guo Z, Yang Y, Yan R (2026) Pellino1 Exacerbates Diabetic Kidney Disease Through NLRP3 Inflammasome Driven Pyroptosis in Renal Tubular Epithelial Cells. FASEB J 40(7):e71721. https:\/\/doi.org\/10.1096\/fj.202504648R","journal-title":"FASEB J"},{"key":"2428_CR70","doi-asserted-by":"publisher","first-page":"116172","DOI":"10.1016\/j.intimp.2026.116172","volume":"171","author":"J Wang","year":"2026","unstructured":"Wang J, Yue G, Chen W et al (2026) CDK9-mediated transcriptional activation of NEK7 promotes NLRP3-dependent podocyte Pyroptosis in diabetic kidney disease. Int Immunopharmacol 171:116172. https:\/\/doi.org\/10.1016\/j.intimp.2026.116172","journal-title":"Int Immunopharmacol"},{"issue":"1","key":"2428_CR71","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1038\/s41419-025-07396-4","volume":"16","author":"S Sunilkumar","year":"2025","unstructured":"Sunilkumar S, Subrahmanian SM, Yerlikaya EI et al (2025) REDD1 expression in podocytes facilitates renal inflammation and pyroptosis in streptozotocin-induced diabetic nephropathy. Cell Death Dis 16(1):79. https:\/\/doi.org\/10.1038\/s41419-025-07396-4","journal-title":"Cell Death Dis"},{"issue":"1","key":"2428_CR72","doi-asserted-by":"publisher","first-page":"2497492","DOI":"10.1080\/0886022X.2025.2497492","volume":"47","author":"X Xu","year":"2025","unstructured":"Xu X, Huang X, Zhang C et al (2025) METTL3 promotes podocyte pyroptosis in diabetic nephropathy through N6-methyladenosine modification of TRIM29 mRNA. Ren Fail 47(1):2497492. https:\/\/doi.org\/10.1080\/0886022X.2025.2497492","journal-title":"Ren Fail"},{"issue":"3\u20134","key":"2428_CR73","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1007\/s10495-022-01794-1","volume":"28","author":"D Zhu","year":"2023","unstructured":"Zhu D, Zhong J, Gong X, Wu X (2023) Augmenter of liver regeneration reduces mitochondria-derived ROS and NLRP3 inflammasome activation through PINK1\/Parkin-mediated mitophagy in ischemia-reperfusion-induced renal tubular injury. Apoptosis 28(3\u20134):335\u2013347. https:\/\/doi.org\/10.1007\/s10495-022-01794-1","journal-title":"Apoptosis"},{"issue":"6","key":"2428_CR74","doi-asserted-by":"publisher","first-page":"10452","DOI":"10.1002\/jcb.28330","volume":"120","author":"Z Song","year":"2019","unstructured":"Song Z, Zhang Y, Gong B, Xu H, Hao Z, Liang C (2019) Long noncoding RNA LINC00339 promotes renal tubular epithelial pyroptosis by regulating the miR-22-3p\/NLRP3 axis in calcium oxalate-induced kidney stone. J Cell Biochem 120(6):10452\u201310462. https:\/\/doi.org\/10.1002\/jcb.28330","journal-title":"J Cell Biochem"},{"issue":"1","key":"2428_CR75","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1038\/s41392-024-01958-2","volume":"9","author":"Y Liu","year":"2024","unstructured":"Liu Y, Pan R, Ouyang Y et al (2024) Pyroptosis in health and disease: mechanisms, regulation and clinical perspective. Signal Transduct Target Ther 9(1):245. https:\/\/doi.org\/10.1038\/s41392-024-01958-2","journal-title":"Signal Transduct Target Ther"},{"issue":"1","key":"2428_CR76","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1111\/jdi.13660","volume":"13","author":"S Wen","year":"2022","unstructured":"Wen S, Deng F, Li L, Xu L, Li X, Fan Q (2022) VX-765 ameliorates renal injury and fibrosis in diabetes by regulating caspase-1-mediated pyroptosis and inflammation. J Diabetes Investig 13(1):22\u201333. https:\/\/doi.org\/10.1111\/jdi.13660","journal-title":"J Diabetes Investig"},{"issue":"1","key":"2428_CR77","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1186\/s12967-023-04846-5","volume":"22","author":"S Xie","year":"2024","unstructured":"Xie S, Song S, Liu S et al (2024) (Pro)renin receptor mediates tubular epithelial cell pyroptosis in diabetic kidney disease via DPP4-JNK pathway. J Transl Med 22(1):26. https:\/\/doi.org\/10.1186\/s12967-023-04846-5","journal-title":"J Transl Med"},{"issue":"11","key":"2428_CR78","doi-asserted-by":"publisher","first-page":"1807","DOI":"10.4049\/jimmunol.2300193","volume":"212","author":"T Kagi","year":"2024","unstructured":"Kagi T, Inoue A, Noguchi T et al (2024) The NLRP3 Inflammasome Is a Major Cause of Acute Renal Failure Induced by Polypeptide Antibiotics. J Immunol 212(11):1807\u20131818. https:\/\/doi.org\/10.4049\/jimmunol.2300193","journal-title":"J Immunol"},{"key":"2428_CR79","doi-asserted-by":"publisher","first-page":"796724","DOI":"10.3389\/fmed.2021.796724","volume":"8","author":"C Li","year":"2021","unstructured":"Li C, Wang W, Xie SS et al (2021) The Programmed Cell Death of Macrophages, Endothelial Cells, and Tubular Epithelial Cells in Sepsis-AKI. Front Med (Lausanne) 8:796724. https:\/\/doi.org\/10.3389\/fmed.2021.796724","journal-title":"Front Med (Lausanne)"},{"issue":"8","key":"2428_CR80","doi-asserted-by":"publisher","first-page":"1589","DOI":"10.1097\/TP.0000000000004038","volume":"106","author":"SE DeWolf","year":"2022","unstructured":"DeWolf SE, Kasimsetty SG, Hawkes AA, Stocks LM, Kurian SM, McKay DB (2022) DAMPs Released From Injured Renal Tubular Epithelial Cells Activate Innate Immune Signals in Healthy Renal Tubular Epithelial Cells. Transplantation 106(8):1589\u20131599. https:\/\/doi.org\/10.1097\/TP.0000000000004038","journal-title":"Transplantation"},{"key":"2428_CR81","doi-asserted-by":"publisher","unstructured":"Liu X, Chen Q, Chen X et al (2026) TREM1-NLRP3-driven pyroptosis in sepsis-associated acute kidney injury (AKI) with parallel autophagy changes. Sci Rep 16(1). https:\/\/doi.org\/10.1038\/s41598-026-40893-w","DOI":"10.1038\/s41598-026-40893-w"},{"key":"2428_CR82","doi-asserted-by":"publisher","first-page":"1624850","DOI":"10.3389\/fimmu.2025.1624850","volume":"16","author":"C Dong","year":"2025","unstructured":"Dong C, Wu M, Liu H et al (2025) Breaking the cycle: immune complexes, complement activation, and novel immunotherapies in lupus nephritis. Front Immunol 16:1624850. https:\/\/doi.org\/10.3389\/fimmu.2025.1624850","journal-title":"Front Immunol"},{"issue":"1","key":"2428_CR83","doi-asserted-by":"publisher","first-page":"1139","DOI":"10.1186\/s12967-024-05951-9","volume":"22","author":"Y Lai","year":"2024","unstructured":"Lai Y, Zhuang L, Zhu J et al (2024) Novel approach to alleviate lupus nephritis: targeting the NLRP3 inflammasome in CD8\u2009+\u2009CD69+CD103\u2009+\u2009TRM cells. J Transl Med 22(1):1139. https:\/\/doi.org\/10.1186\/s12967-024-05951-9","journal-title":"J Transl Med"},{"issue":"1","key":"2428_CR84","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1038\/s41420-022-01167-2","volume":"8","author":"L Zhuang","year":"2022","unstructured":"Zhuang L, Luo X, Wu S et al (2022) Disulfiram alleviates pristane-induced lupus via inhibiting GSDMD-mediated pyroptosis. Cell Death Discov 8(1):379. https:\/\/doi.org\/10.1038\/s41420-022-01167-2","journal-title":"Cell Death Discov"},{"issue":"1","key":"2428_CR85","doi-asserted-by":"publisher","first-page":"20221038","DOI":"10.1515\/biol-2022-1038","volume":"20","author":"Y Zhao","year":"2025","unstructured":"Zhao Y, Zhang AP, Bao BY, Fan H, Yang XY (2025) Sirt1 protects lupus nephritis by inhibiting the NLRP3 signaling pathway in human glomerular mesangial cells. Open Life Sci 20(1):20221038. https:\/\/doi.org\/10.1515\/biol-2022-1038","journal-title":"Open Life Sci"},{"key":"2428_CR86","doi-asserted-by":"publisher","first-page":"720877","DOI":"10.3389\/fimmu.2021.720877","volume":"12","author":"H Cao","year":"2021","unstructured":"Cao H, Liang J, Liu J et al (2021) Novel Effects of Combination Therapy Through Inhibition of Caspase-1\/Gasdermin D Induced-Pyroptosis in Lupus Nephritis. Front Immunol 12:720877. https:\/\/doi.org\/10.3389\/fimmu.2021.720877","journal-title":"Front Immunol"},{"key":"2428_CR87","doi-asserted-by":"publisher","first-page":"259","DOI":"10.3389\/fcell.2019.00259","volume":"7","author":"J Hong","year":"2019","unstructured":"Hong J, Li G, Zhang Q, Ritter J, Li W, Li PL (2019) D-Ribose Induces Podocyte NLRP3 Inflammasome Activation and Glomerular Injury via AGEs\/RAGE Pathway. Front Cell Dev Biol 7:259. https:\/\/doi.org\/10.3389\/fcell.2019.00259","journal-title":"Front Cell Dev Biol"},{"issue":"1","key":"2428_CR88","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1186\/s12964-024-01728-1","volume":"22","author":"CL Cliff","year":"2024","unstructured":"Cliff CL, Squires PE, Hills CE (2024) Tonabersat suppresses priming\/activation of the NOD-like receptor protein-3 (NLRP3) inflammasome and decreases renal tubular epithelial-to-macrophage crosstalk in a model of diabetic kidney disease. Cell Commun Signal 22(1):351. https:\/\/doi.org\/10.1186\/s12964-024-01728-1","journal-title":"Cell Commun Signal"},{"key":"2428_CR89","doi-asserted-by":"publisher","first-page":"1620230","DOI":"10.3389\/fendo.2025.1620230","volume":"16","author":"X Shi","year":"2025","unstructured":"Shi X, Zou W, Li X et al (2025) SGLT2 inhibition attenuates diabetic tubulopathy by suppressing SGK1-mediated pyroptosis. Front Endocrinol (Lausanne) 16:1620230. https:\/\/doi.org\/10.3389\/fendo.2025.1620230","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"1","key":"2428_CR90","doi-asserted-by":"publisher","first-page":"3200","DOI":"10.1038\/s41467-024-47315-3","volume":"15","author":"L Li","year":"2024","unstructured":"Li L, Xiang T, Guo J et al (2024) Inhibition of ACSS2-mediated histone crotonylation alleviates kidney fibrosis via IL-1\u03b2-dependent macrophage activation and tubular cell senescence. Nat Commun 15(1):3200. https:\/\/doi.org\/10.1038\/s41467-024-47315-3","journal-title":"Nat Commun"},{"issue":"8","key":"2428_CR91","doi-asserted-by":"publisher","first-page":"3996","DOI":"10.7150\/thno.124015","volume":"16","author":"MS Khan","year":"2026","unstructured":"Khan MS, Kim B, Jeon Y et al (2026) Hyperglycemia in combination with excess fat intake promotes renal pyroptosis and fibrosis through G\u03b112-dependent endoplasmic reticulum stress. Theranostics 16(8):3996\u20134018. https:\/\/doi.org\/10.7150\/thno.124015","journal-title":"Theranostics"},{"key":"2428_CR92","doi-asserted-by":"publisher","unstructured":"Li S, Livingston MJ, Ma Z et al (2023) Tubular cell senescence promotes maladaptive kidney repair and chronic kidney disease after cisplatin nephrotoxicity. JCI Insight 8(8). https:\/\/doi.org\/10.1172\/jci.insight.166643","DOI":"10.1172\/jci.insight.166643"},{"issue":"1","key":"2428_CR93","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1038\/s41401-023-01151-1","volume":"45","author":"JY Li","year":"2024","unstructured":"Li JY, Sun XA, Wang X et al (2024) PGAM5 exacerbates acute renal injury by initiating mitochondria-dependent apoptosis by facilitating mitochondrial cytochrome c release. Acta Pharmacol Sin 45(1):125\u2013136. https:\/\/doi.org\/10.1038\/s41401-023-01151-1","journal-title":"Acta Pharmacol Sin"},{"issue":"10","key":"2428_CR94","doi-asserted-by":"publisher","first-page":"3052","DOI":"10.1016\/j.ymthe.2023.08.014","volume":"31","author":"M Zhu","year":"2023","unstructured":"Zhu M, He J, Xu Y et al (2023) AMPK activation coupling SENP1-Sirt3 axis protects against acute kidney injury. Mol Ther 31(10):3052\u20133066. https:\/\/doi.org\/10.1016\/j.ymthe.2023.08.014","journal-title":"Mol Ther"},{"issue":"11","key":"2428_CR95","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1038\/s41419-023-06247-4","volume":"14","author":"L Shi","year":"2023","unstructured":"Shi L, Zha H, Pan Z et al (2023) DUSP1 protects against ischemic acute kidney injury through stabilizing mtDNA via interaction with JNK. Cell Death Dis 14(11):724. https:\/\/doi.org\/10.1038\/s41419-023-06247-4","journal-title":"Cell Death Dis"},{"issue":"1\u20133","key":"2428_CR96","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1089\/ars.2022.0178","volume":"40","author":"YT Liu","year":"2024","unstructured":"Liu YT, Zhang H, Duan SB et al (2024) Mitofusin2 Ameliorated Endoplasmic Reticulum Stress and Mitochondrial Reactive Oxygen Species Through Maintaining Mitochondria-Associated Endoplasmic Reticulum Membrane Integrity in Cisplatin-Induced Acute Kidney Injury. Antioxid Redox Signal 40(1\u20133):16\u201339. https:\/\/doi.org\/10.1089\/ars.2022.0178","journal-title":"Antioxid Redox Signal"},{"issue":"1","key":"2428_CR97","doi-asserted-by":"publisher","first-page":"24307","DOI":"10.1038\/s41598-024-75229-z","volume":"14","author":"H Kimura","year":"2024","unstructured":"Kimura H, Kamiyama K, Imamoto T et al (2024) Dichloroacetate reduces cisplatin-induced apoptosis by inhibiting the JNK\/14-3-3\/Bax\/caspase-9 pathway and suppressing caspase-8 activation via cFLIP in murine tubular cells. Sci Rep 14(1):24307. https:\/\/doi.org\/10.1038\/s41598-024-75229-z","journal-title":"Sci Rep"},{"issue":"1","key":"2428_CR98","doi-asserted-by":"publisher","first-page":"9436","DOI":"10.1038\/s41467-025-64480-1","volume":"16","author":"XX Zhu","year":"2025","unstructured":"Zhu XX, Meng XY, Zhang AY et al (2025) Inhibition of PGK1 ameliorates acute kidney injury through inactivating the PKM2\/ALOX12\/ferroptosis pathway in a study with male mice. Nat Commun 16(1):9436. https:\/\/doi.org\/10.1038\/s41467-025-64480-1","journal-title":"Nat Commun"},{"key":"2428_CR99","doi-asserted-by":"publisher","first-page":"1276217","DOI":"10.3389\/fcell.2023.1276217","volume":"11","author":"L Zhao","year":"2023","unstructured":"Zhao L, Hao Y, Tang S, Han X, Li R, Zhou X (2023) Energy metabolic reprogramming regulates programmed cell death of renal tubular epithelial cells and might serve as a new therapeutic target for acute kidney injury. Front Cell Dev Biol 11:1276217. https:\/\/doi.org\/10.3389\/fcell.2023.1276217","journal-title":"Front Cell Dev Biol"},{"issue":"1","key":"2428_CR100","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1038\/s41419-025-07386-6","volume":"16","author":"K Giuliani","year":"2025","unstructured":"Giuliani K, Nag P, Adams BC et al (2025) Human proximal tubular epithelial cell interleukin-1 receptor signalling triggers G2\/M arrest and cellular senescence during hypoxic kidney injury. Cell Death Dis 16(1):61. https:\/\/doi.org\/10.1038\/s41419-025-07386-6","journal-title":"Cell Death Dis"},{"issue":"10","key":"2428_CR101","doi-asserted-by":"publisher","first-page":"672","DOI":"10.1038\/s41419-023-06209-w","volume":"14","author":"X Liu","year":"2023","unstructured":"Liu X, Liu Z, Wang C et al (2023) Kidney tubular epithelial cells control interstitial fibroblast fate by releasing TNFAIP8-encapsulated exosomes. Cell Death Dis 14(10):672. https:\/\/doi.org\/10.1038\/s41419-023-06209-w","journal-title":"Cell Death Dis"},{"issue":"2","key":"2428_CR102","doi-asserted-by":"publisher","first-page":"F223","DOI":"10.1152\/ajprenal.00292.2025","volume":"330","author":"N Cintron Pregosin","year":"2026","unstructured":"Cintron Pregosin N, Guo Y, Dang ET et al (2026) Rapid podocyte loss in murine models triggers the formation of podocyte-parietal epithelial cell intercellular bridges. Am J Physiol Ren Physiol 330(2):F223\u2013F237. https:\/\/doi.org\/10.1152\/ajprenal.00292.2025","journal-title":"Am J Physiol Ren Physiol"},{"issue":"8","key":"2428_CR103","doi-asserted-by":"publisher","first-page":"2291","DOI":"10.1111\/febs.70333","volume":"293","author":"M Watanabe","year":"2026","unstructured":"Watanabe M, Kakutani M, Nakano K, Okamura T, Sasaki N (2026) An inducible and podocyte-specific diphtheria toxin receptor knock-in mouse model for studying glomerular injury and chronic kidney disease progression. FEBS J 293(8):2291\u20132313. https:\/\/doi.org\/10.1111\/febs.70333","journal-title":"FEBS J"},{"issue":"6","key":"2428_CR104","doi-asserted-by":"publisher","first-page":"112673","DOI":"10.1016\/j.isci.2025.112673","volume":"28","author":"CR Williamson","year":"2025","unstructured":"Williamson CR, Martin CE, Kumar JD et al (2025) Reduced nephrin tyrosine phosphorylation impairs podocyte force transmission and accelerates detachment in disease. iScience 28(6):112673. https:\/\/doi.org\/10.1016\/j.isci.2025.112673","journal-title":"iScience"},{"issue":"8","key":"2428_CR105","doi-asserted-by":"publisher","first-page":"2980","DOI":"10.7150\/ijbs.96812","volume":"20","author":"W Jiang","year":"2024","unstructured":"Jiang W, Tang TT, Zhang YL et al (2024) CD8 T cells induce the peritubular capillary rarefaction during AKI to CKD transition. Int J Biol Sci 20(8):2980\u20132993. https:\/\/doi.org\/10.7150\/ijbs.96812","journal-title":"Int J Biol Sci"},{"key":"2428_CR106","doi-asserted-by":"publisher","unstructured":"Migneault F, Kim H, Doreille A et al (2025) Endothelial extracellular vesicle miR-423-5p regulates microvascular homeostasis and renal function after ischemia-reperfusion injury. JCI Insight 10(10). https:\/\/doi.org\/10.1172\/jci.insight.181937","DOI":"10.1172\/jci.insight.181937"},{"key":"2428_CR107","doi-asserted-by":"publisher","first-page":"103795","DOI":"10.1016\/j.redox.2025.103795","volume":"86","author":"S Chen","year":"2025","unstructured":"Chen S, Chen T, Xu C et al (2025) Iron overload exaggerates renal ischemia-reperfusion injury by promoting tubular cuproptosis via interrupting function of LIAS. Redox Biol 86:103795. https:\/\/doi.org\/10.1016\/j.redox.2025.103795","journal-title":"Redox Biol"},{"issue":"1","key":"2428_CR108","doi-asserted-by":"publisher","first-page":"2518227","DOI":"10.1080\/0886022X.2025.2518227","volume":"47","author":"L Wang","year":"2025","unstructured":"Wang L, Jiang L, Wang J et al (2025) Reduced glutathione ameliorates sepsis-induced acute kidney injury in mouse model: involvement of cuproptosis. Ren Fail 47(1):2518227. https:\/\/doi.org\/10.1080\/0886022X.2025.2518227","journal-title":"Ren Fail"},{"key":"2428_CR109","doi-asserted-by":"publisher","first-page":"11849","DOI":"10.2147\/DDDT.S562664","volume":"19","author":"D Lv","year":"2025","unstructured":"Lv D, Yu Y (2025) Copper-Induced Cell Death in Renal Diseases: Molecular Mechanisms and Therapeutic Implications. Drug Des Devel Ther 19:11849\u201311861. https:\/\/doi.org\/10.2147\/DDDT.S562664","journal-title":"Drug Des Devel Ther"},{"issue":"4","key":"2428_CR110","doi-asserted-by":"publisher","first-page":"1845","DOI":"10.7150\/thno.50905","volume":"11","author":"M Zhao","year":"2021","unstructured":"Zhao M, Wang Y, Li L et al (2021) Mitochondrial ROS promote mitochondrial dysfunction and inflammation in ischemic acute kidney injury by disrupting TFAM-mediated mtDNA maintenance. Theranostics 11(4):1845\u20131863. https:\/\/doi.org\/10.7150\/thno.50905","journal-title":"Theranostics"},{"issue":"2","key":"2428_CR111","doi-asserted-by":"publisher","first-page":"e0342335","DOI":"10.1371\/journal.pone.0342335","volume":"21","author":"L Zhang","year":"2026","unstructured":"Zhang L, Luo F, Chai Y et al (2026) IL-22 inhibits ferroptosis and attenuates ischemia-reperfusion-induced acute kidney injury: Association with activation of the P62-Keap1-Nrf2 signaling pathway. PLoS ONE 21(2):e0342335. https:\/\/doi.org\/10.1371\/journal.pone.0342335","journal-title":"PLoS ONE"},{"issue":"1","key":"2428_CR112","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1186\/s12964-024-01556-3","volume":"22","author":"J Lu","year":"2024","unstructured":"Lu J, Hou Y, Liu SX et al (2024) Acetyl-CoA synthetase 2 induces pyroptosis and inflammation of renal epithelial tubular cells in sepsis-induced acute kidney injury by upregulating the KLF5\/NF-\u03baB pathway. Cell Commun Signal 22(1):187. https:\/\/doi.org\/10.1186\/s12964-024-01556-3","journal-title":"Cell Commun Signal"},{"key":"2428_CR113","doi-asserted-by":"publisher","unstructured":"Li Z, Wang X, Peng Y et al (2023) Nlrp3 Deficiency Alleviates Lipopolysaccharide-Induced Acute Kidney Injury via Suppressing Renal Inflammation and Ferroptosis in Mice. Biology (Basel) 12(9). https:\/\/doi.org\/10.3390\/biology12091188","DOI":"10.3390\/biology12091188"},{"key":"2428_CR114","doi-asserted-by":"publisher","first-page":"114655","DOI":"10.1016\/j.ecoenv.2023.114655","volume":"253","author":"D Zhang","year":"2023","unstructured":"Zhang D, Wu C, Ba D et al (2023) Ferroptosis contribute to neonicotinoid imidacloprid-evoked pyroptosis by activating the HMGB1-RAGE\/TLR4-NF-\u03baB signaling pathway. Ecotoxicol Environ Saf 253:114655. https:\/\/doi.org\/10.1016\/j.ecoenv.2023.114655","journal-title":"Ecotoxicol Environ Saf"},{"issue":"6","key":"2428_CR115","doi-asserted-by":"publisher","first-page":"1928","DOI":"10.1007\/s13577-023-00949-9","volume":"36","author":"S Lin","year":"2023","unstructured":"Lin S, Wang J, Cao B, Huang Y, Sheng X, Zhu Y (2023) Cofilin-1 induces acute kidney injury via the promotion of endoplasmic reticulum stress-mediated ferroptosis. Hum Cell 36(6):1928\u20131937. https:\/\/doi.org\/10.1007\/s13577-023-00949-9","journal-title":"Hum Cell"},{"key":"2428_CR116","doi-asserted-by":"publisher","first-page":"1545972","DOI":"10.3389\/fphar.2025.1545972","volume":"16","author":"Z Huang","year":"2025","unstructured":"Huang Z, Zhou L, Liu B, Li X, Sang Y (2025) Endoplasmic reticulum stress aggravates ferroptosis via PERK\/ATF4\/HSPA5 pathway in UUO-induced renal fibrosis. Front Pharmacol 16:1545972. https:\/\/doi.org\/10.3389\/fphar.2025.1545972","journal-title":"Front Pharmacol"},{"issue":"1","key":"2428_CR117","doi-asserted-by":"publisher","first-page":"17257","DOI":"10.1038\/s41598-023-44538-0","volume":"13","author":"S Wang","year":"2023","unstructured":"Wang S, Sang X, Li S et al (2023) Increased Ca2\u2009+\u2009transport across the mitochondria-associated membranes by Mfn2 inhibiting endoplasmic reticulum stress in ischemia\/reperfusion kidney injury. Sci Rep 13(1):17257. https:\/\/doi.org\/10.1038\/s41598-023-44538-0","journal-title":"Sci Rep"},{"issue":"4","key":"2428_CR118","doi-asserted-by":"publisher","first-page":"267","DOI":"10.3892\/mmr.2025.13632","volume":"32","author":"S Yoo","year":"2025","unstructured":"Yoo S, Kim M, Bae JY, Lee SA, Koh G (2025) Bardoxolone methyl inhibits ferroptosis through the Keap1\u2013Nrf2 pathway in renal tubular epithelial cells. Mol Med Rep 32(4):267 [pii]. https:\/\/doi.org\/10.3892\/mmr.2025.13632","journal-title":"Mol Med Rep"},{"issue":"21","key":"2428_CR119","doi-asserted-by":"publisher","first-page":"e71193","DOI":"10.1096\/fj.202502377R","volume":"39","author":"YL Yan","year":"2025","unstructured":"Yan YL, Wu YJ, Liao TQ et al (2025) Senkyunolide I Alleviated Renal Fibrosis in UUO Mice by Regulating the Nrf2\/xCT\/GPX4 and NLRP3\/Caspase-1\/GSDMD Pathways to Inhibit Ferroptosis and Pyroptosis. FASEB J 39(21):e71193. https:\/\/doi.org\/10.1096\/fj.202502377R","journal-title":"FASEB J"},{"key":"2428_CR120","doi-asserted-by":"publisher","first-page":"1508047","DOI":"10.3389\/fphar.2025.1508047","volume":"16","author":"Y Zhang","year":"2025","unstructured":"Zhang Y, Hu J, Zhang Y, Ci X (2025) Amentoflavone protects against cisplatin-induced acute kidney injury by modulating Nrf2-mediated oxidative stress and ferroptosis and partially by activating Nrf2-dependent PANoptosis. Front Pharmacol 16:1508047. https:\/\/doi.org\/10.3389\/fphar.2025.1508047","journal-title":"Front Pharmacol"},{"issue":"9\u201310","key":"2428_CR121","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1007\/s10495-020-01627-z","volume":"25","author":"YS Lee","year":"2020","unstructured":"Lee YS, Kalimuthu K, Park YS et al (2020) BAX-dependent mitochondrial pathway mediates the crosstalk between ferroptosis and apoptosis. Apoptosis 25(9\u201310):625\u2013631. https:\/\/doi.org\/10.1007\/s10495-020-01627-z","journal-title":"Apoptosis"},{"issue":"10","key":"2428_CR122","doi-asserted-by":"publisher","first-page":"3084","DOI":"10.1016\/j.ymthe.2023.07.026","volume":"31","author":"L Gao","year":"2023","unstructured":"Gao L, Zhang J, Yang T et al (2023) STING\/ACSL4 axis-dependent ferroptosis and inflammation promote hypertension-associated chronic kidney disease. Mol Ther 31(10):3084\u20133103. https:\/\/doi.org\/10.1016\/j.ymthe.2023.07.026","journal-title":"Mol Ther"},{"issue":"5","key":"2428_CR123","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1038\/s41556-024-01405-y","volume":"26","author":"Z Li","year":"2024","unstructured":"Li Z, Hu Y, Zheng H et al (2024) LPCAT1-mediated membrane phospholipid remodelling promotes ferroptosis evasion and tumour growth. Nat Cell Biol 26(5):811\u2013824. https:\/\/doi.org\/10.1038\/s41556-024-01405-y","journal-title":"Nat Cell Biol"},{"key":"2428_CR124","doi-asserted-by":"publisher","first-page":"1643829","DOI":"10.3389\/fmolb.2025.1643829","volume":"12","author":"Y Zhu","year":"2025","unstructured":"Zhu Y, Lv C, Qiao Y et al (2025) Transformation of acute kidney injury to chronic kidney disease: the interaction between mitophagy and NLRP3 inflammasome. Front Mol Biosci 12:1643829. https:\/\/doi.org\/10.3389\/fmolb.2025.1643829","journal-title":"Front Mol Biosci"},{"issue":"1","key":"2428_CR125","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1186\/s12964-023-01267-1","volume":"21","author":"Y Li","year":"2023","unstructured":"Li Y, Du Y, Zhou Y et al (2023) Iron and copper: critical executioners of ferroptosis, cuproptosis and other forms of cell death. Cell Commun Signal 21(1):327. https:\/\/doi.org\/10.1186\/s12964-023-01267-1","journal-title":"Cell Commun Signal"},{"key":"2428_CR126","doi-asserted-by":"publisher","unstructured":"Qiao Z, Zhou D, Zhang T et al (2026) IFI16 is essential to linking DNA damage and ferroptosis in acute kidney injury. Cell Death Dis 17(1). https:\/\/doi.org\/10.1038\/s41419-026-08604-5","DOI":"10.1038\/s41419-026-08604-5"},{"issue":"1","key":"2428_CR127","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1038\/s41420-024-02113-0","volume":"10","author":"Z Xiao","year":"2024","unstructured":"Xiao Z, Zhang J, Qiu Z et al (2024) Ferroptosis and inflammation are modulated by the NFIL3-ACSL4 axis in sepsis associated-acute kidney injury. Cell Death Discov 10(1):349. https:\/\/doi.org\/10.1038\/s41420-024-02113-0","journal-title":"Cell Death Discov"},{"issue":"5","key":"2428_CR128","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1038\/s41581-023-00694-0","volume":"19","author":"AB Sanz","year":"2023","unstructured":"Sanz AB, Sanchez-Ni\u00f1o MD, Ramos AM, Ortiz A (2023) Regulated cell death pathways in kidney disease. Nat Rev Nephrol 19(5):281\u2013299. https:\/\/doi.org\/10.1038\/s41581-023-00694-0","journal-title":"Nat Rev Nephrol"},{"issue":"1","key":"2428_CR129","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1038\/s41435-025-00364-0","volume":"27","author":"Y Wang","year":"2026","unstructured":"Wang Y, Zhu C, Lv S et al (2026) Spatiotemporal transcriptomic insights into ferroptosis and TFRC-linked immune interactions in ischemia-reperfusion acute kidney injury. Genes Immun 27(1):25\u201340. https:\/\/doi.org\/10.1038\/s41435-025-00364-0","journal-title":"Genes Immun"},{"issue":"1","key":"2428_CR130","doi-asserted-by":"publisher","first-page":"2536732","DOI":"10.1080\/0886022X.2025.2536732","volume":"47","author":"H Wang","year":"2025","unstructured":"Wang H, Sun J, Luo Y, Li X, Li J (2025) The role of ferroptosis in acute kidney injury: the preemptive mode of cell death and the bridging effect. Ren Fail 47(1):2536732. https:\/\/doi.org\/10.1080\/0886022X.2025.2536732","journal-title":"Ren Fail"},{"key":"2428_CR131","doi-asserted-by":"publisher","unstructured":"Jativa S, Torrico S, Mu\u00f1oz A, Torres Salido MT, Hotter G (2026) Cells\u2019 survival pattern of kidney macrophages and epithelial cells in lupus nephritis is influenced by glycolysis. Lupus Sci Med 13(1). https:\/\/doi.org\/10.1136\/lupus-2025-001933","DOI":"10.1136\/lupus-2025-001933"},{"issue":"3","key":"2428_CR132","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1681\/ASN.0000000857","volume":"37","author":"YL Zhang","year":"2026","unstructured":"Zhang YL, Li XY, Tang TT et al (2026) Metabolic Dysregulation of 27-Hydroxycholesterol Sensitizes Proximal Tubular Epithelial Cells to Ferroptosis in Ischemic Acute Kidney Injury. J Am Soc Nephrol 37(3):445\u2013459. https:\/\/doi.org\/10.1681\/ASN.0000000857","journal-title":"J Am Soc Nephrol"},{"key":"2428_CR133","doi-asserted-by":"publisher","first-page":"123924","DOI":"10.1016\/j.lfs.2025.123924","volume":"380","author":"H Zhang","year":"2025","unstructured":"Zhang H, Zhang G, Wang B, Xiong F, Ji X, Wang C (2025) Integrated multi-omics profiling identifies Cmpk1 as a monocyte-specific therapeutic target for renal ischemia-reperfusion injury. Life Sci 380:123924. https:\/\/doi.org\/10.1016\/j.lfs.2025.123924","journal-title":"Life Sci"},{"key":"2428_CR134","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.1016\/j.jare.2025.05.055","volume":"81","author":"CY Lian","year":"2026","unstructured":"Lian CY, Xia WH, Sun MC, Wan XM, Zhou XL, Wang L (2026) Cadmium targeting MLKL-Drp1 axis to trigger mitochondrial oxidative stress contributes to necroinflammation in rat kidney. J Adv Res 81:1079\u20131093. https:\/\/doi.org\/10.1016\/j.jare.2025.05.055","journal-title":"J Adv Res"},{"key":"2428_CR135","doi-asserted-by":"publisher","first-page":"1251452","DOI":"10.3389\/fimmu.2023.1251452","volume":"14","author":"A Pefanis","year":"2023","unstructured":"Pefanis A, Bongoni AK, McRae JL et al (2023) Dynamics of necroptosis in kidney ischemia-reperfusion injury. Front Immunol 14:1251452. https:\/\/doi.org\/10.3389\/fimmu.2023.1251452","journal-title":"Front Immunol"},{"key":"2428_CR136","doi-asserted-by":"publisher","DOI":"10.1113\/EP092229","author":"H Yin","year":"2025","unstructured":"Yin H, Wang J, Han H (2025) Role of RIPK1\/RIPK3\/MLKL signalling pathway in sepsis-associated acute kidney injury. Exp Physiol. https:\/\/doi.org\/10.1113\/EP092229","journal-title":"Exp Physiol"},{"key":"2428_CR137","doi-asserted-by":"publisher","unstructured":"Liu X, Zhang C, Fu Y, Xie L, Kong Y, Yang X (2025) Inflammation, Apoptosis, and Fibrosis in Diabetic Nephropathy: Molecular Crosstalk in Proximal Tubular Epithelial Cells and Therapeutic Implications. Curr Issues Mol Biol 47(11). https:\/\/doi.org\/10.3390\/cimb47110885","DOI":"10.3390\/cimb47110885"},{"key":"2428_CR138","doi-asserted-by":"publisher","unstructured":"Tran MH, Parris CL, Liu C et al (2025) Sex Differences in the Initiation and Progression of Necroptosis Following Kidney Ischemia-Reperfusion Injury. Biomedicines 13(9). https:\/\/doi.org\/10.3390\/biomedicines13092085","DOI":"10.3390\/biomedicines13092085"},{"key":"2428_CR139","doi-asserted-by":"publisher","unstructured":"Sureshbabu A, Patino E, Ma KC et al (2018) RIPK3 promotes sepsis-induced acute kidney injury via mitochondrial dysfunction. JCI Insight 3(11). https:\/\/doi.org\/10.1172\/jci.insight.98411","DOI":"10.1172\/jci.insight.98411"},{"issue":"1","key":"2428_CR140","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1038\/s41392-023-01410-x","volume":"8","author":"L Liang","year":"2023","unstructured":"Liang L, Wang W, Chen J et al (2023) SARS-CoV-2\u00a0N protein induces acute kidney injury in diabetic mice via the Smad3-Ripk3\/MLKL necroptosis pathway. Signal Transduct Target Ther 8(1):147. https:\/\/doi.org\/10.1038\/s41392-023-01410-x","journal-title":"Signal Transduct Target Ther"},{"issue":"4","key":"2428_CR141","doi-asserted-by":"publisher","first-page":"F431","DOI":"10.1152\/ajprenal.00171.2021","volume":"321","author":"HS Jang","year":"2021","unstructured":"Jang HS, Noh MR, Ha L, Kim J, Padanilam BJ (2021) Proximal tubule cyclophilin D mediates kidney fibrogenesis in obstructive nephropathy. Am J Physiol Ren Physiol 321(4):F431\u2013F442. https:\/\/doi.org\/10.1152\/ajprenal.00171.2021","journal-title":"Am J Physiol Ren Physiol"},{"issue":"3","key":"2428_CR142","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1681\/ASN.2021101293","volume":"33","author":"F Maremonti","year":"2022","unstructured":"Maremonti F, Meyer C, Linkermann A (2022) Mechanisms and Models of Kidney Tubular Necrosis and Nephron Loss. J Am Soc Nephrol 33(3):472\u2013486. https:\/\/doi.org\/10.1681\/ASN.2021101293","journal-title":"J Am Soc Nephrol"},{"issue":"11","key":"2428_CR143","doi-asserted-by":"publisher","first-page":"e12278","DOI":"10.1002\/advs.202512278","volume":"13","author":"Y Xu","year":"2026","unstructured":"Xu Y, Wang Y, Jiang S et al (2026) Tubule-Derived IFN-\u03b1 Promotes GSDMD-Mediated Macrophage Pyroptosis to Drive Renal Inflammation and Fibrosis Through JAK2\/STAT2 Activation. Adv Sci (Weinh) 13(11):e12278. https:\/\/doi.org\/10.1002\/advs.202512278","journal-title":"Adv Sci (Weinh)"},{"issue":"4","key":"2428_CR144","doi-asserted-by":"publisher","first-page":"997","DOI":"10.1142\/S0192415X23500465","volume":"51","author":"Q Feng","year":"2023","unstructured":"Feng Q, Yang Y, Qiao Y et al (2023) Quercetin Ameliorates Diabetic Kidney Injury by Inhibiting Ferroptosis via Activating Nrf2\/HO-1 Signaling Pathway. Am J Chin Med 51(4):997\u20131018. https:\/\/doi.org\/10.1142\/S0192415X23500465","journal-title":"Am J Chin Med"},{"key":"2428_CR145","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1016\/j.freeradbiomed.2022.05.024","volume":"187","author":"Q Li","year":"2022","unstructured":"Li Q, Liao J, Chen W et al (2022) NAC alleviative ferroptosis in diabetic nephropathy via maintaining mitochondrial redox homeostasis through activating SIRT3-SOD2\/Gpx4 pathway. Free Radic Biol Med 187:158\u2013170. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2022.05.024","journal-title":"Free Radic Biol Med"},{"issue":"4","key":"2428_CR146","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1056\/NEJMoa1105351","volume":"365","author":"PE Pergola","year":"2011","unstructured":"Pergola PE, Raskin P, Toto RD et al (2011) Bardoxolone methyl and kidney function in CKD with type 2 diabetes. N Engl J Med 365(4):327\u2013336. https:\/\/doi.org\/10.1056\/NEJMoa1105351","journal-title":"N Engl J Med"},{"issue":"26","key":"2428_CR147","doi-asserted-by":"publisher","first-page":"2492","DOI":"10.1056\/NEJMoa1306033","volume":"369","author":"D de Zeeuw","year":"2013","unstructured":"de Zeeuw D, Akizawa T, Audhya P et al (2013) Bardoxolone methyl in type 2 diabetes and stage 4 chronic kidney disease. N Engl J Med 369(26):2492\u20132503. https:\/\/doi.org\/10.1056\/NEJMoa1306033","journal-title":"N Engl J Med"},{"issue":"5","key":"2428_CR148","doi-asserted-by":"publisher","first-page":"1204","DOI":"10.1093\/ndt\/gfac242","volume":"38","author":"M Nangaku","year":"2023","unstructured":"Nangaku M, Takama H, Ichikawa T et al (2023) Randomized, double-blind, placebo-controlled phase 3 study of bardoxolone methyl in patients with diabetic kidney disease: design and baseline characteristics of the AYAME study. Nephrol Dial Transpl 38(5):1204\u20131216. https:\/\/doi.org\/10.1093\/ndt\/gfac242","journal-title":"Nephrol Dial Transpl"},{"issue":"6","key":"2428_CR149","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1016\/j.ekir.2020.03.030","volume":"5","author":"M Nangaku","year":"2020","unstructured":"Nangaku M, Kanda H, Takama H, Ichikawa T, Hase H, Akizawa T (2020) Randomized Clinical Trial on the Effect of Bardoxolone Methyl on GFR in Diabetic Kidney Disease Patients (TSUBAKI Study). Kidney Int Rep 5(6):879\u2013890. https:\/\/doi.org\/10.1016\/j.ekir.2020.03.030","journal-title":"Kidney Int Rep"},{"issue":"28","key":"2428_CR150","doi-asserted-by":"publisher","first-page":"3261","DOI":"10.2174\/0929867329666220922104654","volume":"30","author":"M Yang","year":"2023","unstructured":"Yang M, Zhao L (2023) The Selective NLRP3-Inflammasome Inhibitor CY-09 Ameliorates Kidney Injury in Diabetic Nephropathy by Inhibiting NLRP3- inflammasome Activation. Curr Med Chem 30(28):3261\u20133270. https:\/\/doi.org\/10.2174\/0929867329666220922104654","journal-title":"Curr Med Chem"},{"issue":"1","key":"2428_CR151","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1080\/13880209.2025.2498166","volume":"63","author":"X Yang","year":"2025","unstructured":"Yang X, Luo Q, Wu Z et al (2025) Tanshinone IIA reduces tubulointerstitial fibrosis by suppressing GSDMD-mediated pyroptosis. Pharm Biol 63(1):364\u2013373. https:\/\/doi.org\/10.1080\/13880209.2025.2498166","journal-title":"Pharm Biol"},{"key":"2428_CR152","doi-asserted-by":"publisher","unstructured":"Hossamelden S, Shaheen SM, Shousha GAH, Sayed R (2025) Curcumin Benefits in Children with Active Lupus Nephritis via NLRP3 Inflammasome Inhibition\u2014A Randomized Controlled Trial. Adv Ther (Weinh) 8(12). https:\/\/doi.org\/10.1002\/adtp.202500160","DOI":"10.1002\/adtp.202500160"},{"key":"2428_CR153","doi-asserted-by":"publisher","first-page":"1703560","DOI":"10.3389\/fimmu.2025.1703560","volume":"16","author":"Y Luo","year":"2025","unstructured":"Luo Y, Long M, Wu X, Zeng L (2025) Targeting the NLRP3 inflammasome in kidney disease: molecular mechanisms, pathogenic roles, and emerging small-molecule therapeutics. Front Immunol 16:1703560. https:\/\/doi.org\/10.3389\/fimmu.2025.1703560","journal-title":"Front Immunol"},{"key":"2428_CR154","doi-asserted-by":"publisher","unstructured":"Wang L, Chen Z, Weng X, Wang M, Du Y, Liu X (2019) Combined Ischemic Postconditioning and Ozone Postconditioning Provides Synergistic Protection Against Renal Ischemia and Reperfusion Injury Through Inhibiting Pyroptosis. Urology 123. https:\/\/doi.org\/10.1016\/j.urology.2018.10.015. :296.e1-296.e8","DOI":"10.1016\/j.urology.2018.10.015"},{"issue":"1","key":"2428_CR155","doi-asserted-by":"publisher","first-page":"e70162","DOI":"10.14814\/phy2.70162","volume":"13","author":"Y Wu","year":"2025","unstructured":"Wu Y, Xv Y, Zhao L et al (2025) PSTK exerts protective role in cisplatin-tubular cell injury via BAX\/BCL2\/Caspase3 pathway. Physiol Rep 13(1):e70162. https:\/\/doi.org\/10.14814\/phy2.70162","journal-title":"Physiol Rep"}],"container-title":["Apoptosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10495-026-02428-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10495-026-02428-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10495-026-02428-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T19:10:03Z","timestamp":1789672203000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10495-026-02428-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,20]]},"references-count":155,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["2428"],"URL":"https:\/\/doi.org\/10.1007\/s10495-026-02428-6","relation":{},"ISSN":["1360-8185","1573-675X"],"issn-type":[{"value":"1360-8185","type":"print"},{"value":"1573-675X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,20]]},"assertion":[{"value":"1 July 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 August 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 August 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"209"}}