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This study presents a thematic narrative analysis of interviews from six females (M\u2009=\u200925.5\u00a0yrs; range\u2009=\u200921\u201332\u00a0yrs). All detransitioned after having at least one gender-affirming medical or surgical treatment as part of a gender transition in the UK. Four narrative themes were developed to capture how they made sense of their detransition: (1) the limits of medical transition, (2) the longer-term health implications, (3) the social limits of transition, and (4) detransition as an ongoing process. Participants discussed a range of emotional, practical, and other support needs, largely unmet by healthcare or other services. These findings highlight the importance of ensuring that people have realistic expectations of transition as part of a holistic assessment process. Long-term health outcome research is also needed, addressing the impact of testosterone on female anatomy and health specifically. Further clinical implications with those considering transition or detransition are discussed.<\/jats:p>","DOI":"10.1007\/s10508-025-03083-9","type":"journal-article","created":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T10:46:37Z","timestamp":1744109197000},"page":"1671-1686","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Narratives of Adults Registered Female at Birth Who Started a Medical Transition and Later Detransitioned"],"prefix":"10.1007","volume":"54","author":[{"given":"Jane","family":"Lomax","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3788-4466","authenticated-orcid":false,"given":"Catherine","family":"Butler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,4,7]]},"reference":[{"issue":"6","key":"3083_CR1","doi-asserted-by":"publisher","first-page":"858","DOI":"10.1089\/jwh.2019.8247","volume":"29","author":"ME Arnegard","year":"2020","unstructured":"Arnegard, M. 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