{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:06:22Z","timestamp":1771459582372,"version":"3.50.1"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bull Exp Biol Med"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1007\/s10517-021-05253-w","type":"journal-article","created":{"date-parts":[[2021,9,20]],"date-time":"2021-09-20T05:02:42Z","timestamp":1632114162000},"page":"472-474","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Soluble B7-H3 in Ovarian Cancer and Its Predictive Value"],"prefix":"10.1007","volume":"171","author":[{"given":"O. V.","family":"Kovaleva","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. P.","family":"Belova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. A.","family":"Korotkova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. N.","family":"Kushlinskii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. N.","family":"Gratchev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. A.","family":"Petrikova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. A.","family":"Kudlay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. E.","family":"Kushlinskii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,9,20]]},"reference":[{"issue":"4","key":"5253_CR1","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1134\/S1068162019040101","volume":"45","author":"AI Chapoval","year":"2019","unstructured":"Chapoval AI, Shcherbakova NS, Shcherbakov DN, Chapoval SP. Immune checkpoints of the B7 family. Part 1. General characteristics and first representatives: B7-1, B7-2, B7-H1, B7-H2, and B7-DC. Russ. J. Bioorgan. Chem. 2019;45(4):225-240.","journal-title":"J. Bioorgan. Chem."},{"issue":"1","key":"5253_CR2","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1038\/pcan.2016.49","volume":"20","author":"B Benzon","year":"2017","unstructured":"Benzon B, Zhao SG, Haffner MC, Takhar M, Erho N, Yousefi K, Hurley P, Bishop JL, Tosoian J, Ghabili K, Alshalalfa M, Glavaris S, Simons BW, Tran P, Davicioni E, Karnes RJ, Boudadi K, Antonarakis ES, Schaeffer EM, Drake CG, Feng F, Ross AE. Correlation of B7-H3 with androgen receptor, immune pathways and poor outcome in prostate cancer: an expression-based analysis. Prostate Cancer Prostatic Dis. 2017;20(1):28-35. doi: https:\/\/doi.org\/10.1038\/pcan.2016.49","journal-title":"Prostate Cancer Prostatic Dis."},{"issue":"4","key":"5253_CR3","first-page":"66","volume":"6","author":"JR Castellanos","year":"2017","unstructured":"Castellanos J.R, Purvis I.J, Labak C.M, Guda M.R, Tsung A.J, Velpula K.K, Asuthkar S. B7-H3 role in the immune landscape of cancer. Am. J. Clin. Exp. Immunol. 2017;6(4):66-75.","journal-title":"Am. J. Clin. Exp. Immunol."},{"issue":"3","key":"5253_CR4","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1038\/85339","volume":"2","author":"AI Chapoval","year":"2001","unstructured":"Chapoval AI, Ni J, Lau JS, Wilcox RA, Flies DB, Liu D, Dong H, Sica GL, Zhu G, Tamada K, Chen L. B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production. Nat. Immunol. 2001;2(3):269-274. doi: https:\/\/doi.org\/10.1038\/85339","journal-title":"Nat. Immunol."},{"issue":"6","key":"5253_CR5","doi-asserted-by":"publisher","first-page":"e21341","DOI":"10.1371\/journal.pone.0021341","volume":"6","author":"W Chen","year":"2011","unstructured":"Chen W, Hou Z, Li C, Xiong S, Liu H. Cloning and characterization of porcine 4Ig-B7-H3: a potent inhibitor of porcine T-cell activation. PLoS One. 2011;6(6):e21341. doi: https:\/\/doi.org\/10.1371\/journal.pone.0021341","journal-title":"PLoS One."},{"key":"5253_CR6","doi-asserted-by":"publisher","first-page":"264","DOI":"10.3389\/fonc.2018.00264","volume":"8","author":"P Dong","year":"2018","unstructured":"Dong P, Xiong Y, Yue J, Hanley SJB, Watari H. B7H3 As a promoter of metastasis and promising therapeutic target. Front. Oncol. 2018;8:264. doi: https:\/\/doi.org\/10.3389\/fonc.2018.00264","journal-title":"Front. Oncol."},{"issue":"3","key":"5253_CR7","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1111\/j.1365-2567.2009.03236.x","volume":"130","author":"H Kobori","year":"2010","unstructured":"Kobori H, Hashiguchi M, Piao J, Kato M, Ritprajak P, Azuma M. Enhancement of effector CD8+ T-cell function by tumour-associated B7-H3 and modulation of its counter-receptor triggering receptor expressed on myeloid cell-like transcript 2 at tumour sites. Immunology. 2010;130(3):363-373. doi: https:\/\/doi.org\/10.1111\/j.1365-2567.2009.03236.x","journal-title":"Immunology."},{"issue":"4","key":"5253_CR8","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1038\/nrc3239","volume":"12","author":"DM Pardoll","year":"2012","unstructured":"Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat. Rev. Cancer. 2012;12(4):252-264. doi: https:\/\/doi.org\/10.1038\/nrc3239","journal-title":"Nat. Rev. Cancer."},{"issue":"4","key":"5253_CR9","doi-asserted-by":"publisher","first-page":"2352","DOI":"10.4049\/jimmunol.172.4.2352","volume":"172","author":"P Steinberger","year":"2004","unstructured":"Steinberger P, Majdic O, Derdak SV, Pfistershammer K, Kirchberger S, Klauser C, Zlabinger G, Pickl WF, St\u00f6ckl J, Knapp W. Molecular characterization of human 4Ig-B7-H3, a member of the B7 family with four Ig-like domains. J. Immunol. 2004;172(4):2352-2359. doi: https:\/\/doi.org\/10.4049\/jimmunol.172.4.2352","journal-title":"J. Immunol."},{"issue":"8","key":"5253_CR10","doi-asserted-by":"publisher","first-page":"1163","DOI":"10.1007\/s00262-010-0841-1","volume":"59","author":"J Sun","year":"2010","unstructured":"Sun J, Chen LJ, Zhang GB, Jiang JT, Zhu M, Tan Y, Wang HT, Lu BF, Zhang XG. Clinical significance and regulation of the costimulatory molecule B7-H3 in human colorectal carcinoma. Cancer Immunol. Immunother. 2010;59(8):1163-1171. doi: https:\/\/doi.org\/10.1007\/s00262-010-0841-1","journal-title":"Cancer Immunol. Immunother."},{"issue":"9","key":"5253_CR11","doi-asserted-by":"publisher","first-page":"e24751","DOI":"10.1371\/journal.pone.0024751","volume":"6","author":"J Sun","year":"2011","unstructured":"Sun J, Fu F, Gu W, Yan R, Zhang G, Shen Z, Zhou Y, Wang H, Shen B, Zhang X. Origination of new immunological functions in the costimulatory molecule B7-H3: the role of exon duplication in evolution of the immune system. PLoS One. 2011;6(9):e24751. doi: https:\/\/doi.org\/10.1371\/journal.pone.0024751","journal-title":"PLoS One."},{"issue":"5","key":"5253_CR12","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1016\/j.str.2013.03.003","volume":"21","author":"V Vigdorovich","year":"2013","unstructured":"Vigdorovich V, Ramagopal UA, L\u00e1z\u00e1r-Moln\u00e1r E, Sylvestre E, Lee JS, Hofmeyer KA, Zang X, Nathenson SG, Almo SC. Structure and T cell inhibition properties of B7 family member, B7-H3. Structure. 2013;21(5):707-717. doi: https:\/\/doi.org\/10.1016\/j.str.2013.03.003","journal-title":"Structure."},{"key":"5253_CR13","doi-asserted-by":"publisher","first-page":"27528","DOI":"10.1038\/srep27528","volume":"6","author":"C Xie","year":"2016","unstructured":"Xie C, Liu D, Chen Q, Yang C, Wang B, Wu H. Soluble B7-H3 promotes the invasion and metastasis of pancreatic carcinoma cells through the TLR4\/NF-\u03baB pathway. Sci. Rep. 2016;6:27528. doi: https:\/\/doi.org\/10.1038\/srep27528","journal-title":"Sci. Rep."},{"issue":"6","key":"5253_CR14","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1089\/mab.2013.0052","volume":"32","author":"R Yan","year":"2013","unstructured":"Yan R, Yang S, Gu A, Zhan F, He C, Qin C, Zhang X, Feng P. Murine b7-h3 is a co-stimulatory molecule for T cell activation. Monoclon. Antib. Immunodiagn. Immunother. 2013;32(6):395-398. doi: https:\/\/doi.org\/10.1089\/mab.2013.0052","journal-title":"Monoclon. Antib. Immunodiagn. Immunother."},{"issue":"4","key":"5253_CR15","doi-asserted-by":"publisher","first-page":"2426","DOI":"10.3892\/or.2017.5858","volume":"38","author":"J Zhang","year":"2017","unstructured":"Zhang J, Liu L, Han S, Li Y, Qian Q, Zhang Q, Zhang H, Yang Z, Zhang Y. B7-H3 is related to tumor progression in ovarian cancer. Oncol. Rep. 2017;38(4):2426-2434. doi: https:\/\/doi.org\/10.3892\/or.2017.5858","journal-title":"Oncol. Rep."}],"container-title":["Bulletin of Experimental Biology and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10517-021-05253-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10517-021-05253-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10517-021-05253-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,29]],"date-time":"2021-09-29T01:23:03Z","timestamp":1632878583000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10517-021-05253-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["5253"],"URL":"https:\/\/doi.org\/10.1007\/s10517-021-05253-w","relation":{},"ISSN":["0007-4888","1573-8221"],"issn-type":[{"value":"0007-4888","type":"print"},{"value":"1573-8221","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8]]},"assertion":[{"value":"26 January 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 September 2021","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}