{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T02:40:28Z","timestamp":1784860828038,"version":"3.55.0"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bull Exp Biol Med"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1007\/s10517-021-05273-6","type":"journal-article","created":{"date-parts":[[2021,10,7]],"date-time":"2021-10-07T03:34:27Z","timestamp":1633577667000},"page":"582-587","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Response of Esophageal Epithelium to Acute and Chronic Stress in Rabbits"],"prefix":"10.1007","volume":"171","author":[{"given":"P.","family":"Erg\u00fcn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Capanoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Kipcak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Bor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,10,7]]},"reference":[{"issue":"3","key":"5273_CR1","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1111\/j.1440-1746.2004.03508.x","volume":"20","author":"V Bhatia","year":"2005","unstructured":"Bhatia V, Tandon RK. Stress and the gastrointestinal tract. J. Gastroenterol. Hepatol. 2005;20(3):332-339. doi: https:\/\/doi.org\/10.1111\/j.1440-1746.2004.03508.x","journal-title":"J. Gastroenterol. Hepatol."},{"issue":"4","key":"5273_CR2","doi-asserted-by":"publisher","first-page":"984","DOI":"10.1007\/s10620-016-4273-4","volume":"62","author":"MM Bilgi","year":"2017","unstructured":"Bilgi MM, Vardar R, Y\u0131ld\u0131r\u0131m E, Veznedaro\u011flu B, Bor S. Prevalence of Psychiatric Comorbidity in Symptomatic Gastroesophageal Reflux Subgroups. Dig. Dis. Sci. 2017;62(4):984-993. doi: https:\/\/doi.org\/10.1007\/s10620-016-4273-4","journal-title":"Dig. Dis. Sci."},{"issue":"1","key":"5273_CR3","first-page":"11","volume":"88","author":"LA Bradley","year":"1993","unstructured":"Bradley LA, Richter JE, Pulliam TJ, Haile JM, Scarinci IC, Schan CA, Dalton CB, Salley AN. The relationship between stress and symptoms of gastroesophageal reflux: the influence of psychological factors. Am. J. Gastroenterol. 1993;88(1): 11-19.","journal-title":"Am. J. Gastroenterol."},{"issue":"7","key":"5273_CR4","doi-asserted-by":"publisher","first-page":"1879","DOI":"10.1007\/s10620-016-4111-8","volume":"61","author":"D Capanoglu","year":"2016","unstructured":"Capanoglu D, Coskunsever D, Olukman M, \u00dclker S, Bor S. Esophageal Epithelial Resistance and Lower Esophageal Sphincter Muscle Contraction Increase in a Chronic Diabetic Rabbit Model. Dig. Dis. Sci. 2016;61(7):1879-1987. doi: https:\/\/doi.org\/10.1007\/s10620-016-4111-8","journal-title":"Dig. Dis. Sci."},{"issue":"3","key":"5273_CR5","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1111\/j.1572-0241.2005.40978.x","volume":"100","author":"R Caviglia","year":"2005","unstructured":"Caviglia R, Ribolsi M, Maggiano N, Gabbrielli AM, Emerenziani S, Guarino MP, Carotti S, Habib FI, Rabitti C, Cicala M. Dilated intercellular spaces of esophageal epithelium in nonerosive reflux disease patients with physiological esophageal acid exposure. Am. J. Gastroenterol. 2005;100(3):543-548. doi: https:\/\/doi.org\/10.1111\/j.1572-0241.2005.40978.x","journal-title":"Am. J. Gastroenterol."},{"issue":"1-3","key":"5273_CR6","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.regpep.2005.09.024","volume":"133","author":"F Ercan","year":"2006","unstructured":"Ercan F, Akici A, Ersoy Y, H\u00fcrdag C, Erin N. Inhibition of substance P activity prevents stress-induced bladder damage. Regul. Pept. 2006;133(1-3):82-89. doi: https:\/\/doi.org\/10.1016\/j.regpep.2005.09.024","journal-title":"Regul. Pept."},{"issue":"9","key":"5273_CR7","doi-asserted-by":"publisher","first-page":"1191","DOI":"10.1136\/gut.2006.113688","volume":"56","author":"R Farr\u00e9","year":"2007","unstructured":"Farr\u00e9 R, De Vos R, Geboes K, Verbecke K, Vanden Berghe P, Depoortere I, Blondeau K, Tack J, Sifrim D. Critical role of stress in increased oesophageal mucosa permeability and dilated intercellular spaces. Gut. 2007;56(9):1191-1197. doi: https:\/\/doi.org\/10.1136\/gut.2006.113688","journal-title":"Gut."},{"key":"5273_CR8","doi-asserted-by":"publisher","unstructured":"Hemmink GJ, Bredenoord AJ, Weusten BL, Timmer R, Smout AJ. Does acute psychological stress increase perception of oesophageal acid? Neurogastroenterol. Motil. 2009;21(10):1055-10e86. doi: https:\/\/doi.org\/10.1111\/j.1365-2982.2009.01327.x","DOI":"10.1111\/j.1365-2982.2009.01327.x"},{"issue":"6","key":"5273_CR9","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1016\/j.jpsychores.2005.05.011","volume":"59","author":"BT Johnston","year":"2005","unstructured":"Johnston BT. Stress and heartburn. J. Psychosom. Res. 2005;59(6):425-426. doi: https:\/\/doi.org\/10.1016\/j.jpsychores.2005.05.011","journal-title":"J. Psychosom. Res."},{"issue":"6","key":"5273_CR10","doi-asserted-by":"publisher","first-page":"C1422","DOI":"10.1152\/ajpcell.00376.2010","volume":"300","author":"T Oshima","year":"2011","unstructured":"Oshima T, Gedda K, Koseki J, Chen X, Husmark J, Watari J, Miwa H, Pierrou S. Establishment of esophageal-like non-keratinized stratified epithelium using normal human bronchial epithelial cells. Am. J. Physiol. Cell Physiol. 2011;300(6):C1422-C1429. doi: https:\/\/doi.org\/10.1152\/ajpcell.00376.2010","journal-title":"Am. J. Physiol. Cell Physiol."},{"issue":"6","key":"5273_CR11","doi-asserted-by":"publisher","first-page":"G847","DOI":"10.1152\/ajpgi.2000.278.6.G847","volume":"278","author":"J Santos","year":"2000","unstructured":"Santos J, Benjamin M, Yang PC, Prior T, Perdue MH. Chronic stress impairs rat growth and jejunal epithelial barrier function: role of mast cells. Am. J. Physiol. Gastrointest. Liver Physiol. 2000;278(6):G847-G854. doi: https:\/\/doi.org\/10.1152\/ajpgi.2000.278.6.G847","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"issue":"5","key":"5273_CR12","doi-asserted-by":"publisher","first-page":"1200","DOI":"10.1053\/gast.1996.v111.pm8898633","volume":"111","author":"NA Tobey","year":"1996","unstructured":"Tobey NA, Carson JL, Alkiek RA, Orlando RC. Dilated intercellular spaces: a morphological feature of acid reflux\u2014damaged human esophageal epithelium. Gastroenterology. 1996;111(5):1200-1205. doi: https:\/\/doi.org\/10.1053\/gast.1996.v111.pm8898633","journal-title":"Gastroenterology."},{"issue":"11","key":"5273_CR13","doi-asserted-by":"publisher","first-page":"3062","DOI":"10.1111\/j.1572-0241.2001.05260.x","volume":"96","author":"NA Tobey","year":"2001","unstructured":"Tobey NA, Hosseini SS, Caymaz-Bor C, Wyatt HR, Orlando GS, Orlando RC. The role of pepsin in acid injury to esophageal epithelium. Am. J. Gastroenterol. 2001;96(11):3062-3070. doi: https:\/\/doi.org\/10.1111\/j.1572-0241.2001.05260.x","journal-title":"Am. J. Gastroenterol."},{"issue":"5","key":"5273_CR14","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1080\/00365520510012235","volume":"40","author":"C Wallon","year":"2005","unstructured":"Wallon C, Braaf Y, Wolving M, Olaison G, S\u00f6derholm JD. Endoscopic biopsies in Ussing chambers evaluated for studies of macromolecular permeability in the human colon. Scand. J. Gastroenterol. 2005;40(5):586-595. doi: https:\/\/doi.org\/10.1080\/00365520510012235","journal-title":"Scand. J. Gastroenterol."},{"issue":"6","key":"5273_CR15","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1016\/j.jpsychores.2005.05.012","volume":"59","author":"CE Wright","year":"2005","unstructured":"Wright CE, Ebrecht M, Mitchell R, Anggiansah A, Weinman J. The effect of psychological stress on symptom severity and perception in patients with gastro-oesophageal reflux. J. Psychosom. Res. 2005;59(6):415-424. doi: https:\/\/doi.org\/10.1016\/j.jpsychores.2005.05.012","journal-title":"J. Psychosom. Res."}],"container-title":["Bulletin of Experimental Biology and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10517-021-05273-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10517-021-05273-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10517-021-05273-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,15]],"date-time":"2021-10-15T06:18:44Z","timestamp":1634278724000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10517-021-05273-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["5273"],"URL":"https:\/\/doi.org\/10.1007\/s10517-021-05273-6","relation":{},"ISSN":["0007-4888","1573-8221"],"issn-type":[{"value":"0007-4888","type":"print"},{"value":"1573-8221","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"5 March 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 October 2021","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}