{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,16]],"date-time":"2025-11-16T00:08:32Z","timestamp":1763251712692,"version":"3.45.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bull Exp Biol Med"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1007\/s10517-025-06522-8","type":"journal-article","created":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T12:26:24Z","timestamp":1762345584000},"page":"532-538","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of Melatonin on the Expression of \u03b12- and \u03b21-Adrenergic Receptors in the Liver of db\/db Mice. Immunohistochemical Characteristics"],"prefix":"10.1007","volume":"179","author":[{"given":"S. V.","family":"Michurina","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. I.","family":"Kolesnikov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. V.","family":"Vasendin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I. Yu.","family":"Ishchenko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. A.","family":"Arkhipov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,11,5]]},"reference":[{"key":"6522_CR1","doi-asserted-by":"publisher","unstructured":"Raikhelson KL, Maevskaya MV, Zharkova MS, et al. Steatotic liver disease: new nomenclature and its localization in the Russian Federation. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2024;34(2):35-44. Russian. https:\/\/doi.org\/10.22416\/1382-4376-2024-961","DOI":"10.22416\/1382-4376-2024-961"},{"key":"6522_CR2","doi-asserted-by":"publisher","first-page":"1291501","DOI":"10.3389\/fmed.2024.1291501","volume":"11","author":"M Habibullah","year":"2024","unstructured":"Habibullah M, Jemmieh K, Ouda A, et al. Metabolicassociated fatty liver disease: a selective review of pathogenesis, diagnostic approaches, and therapeutic strategies. Front Med (Lausanne). 2024;11:1291501. https:\/\/doi.org\/10.3389\/fmed.2024.1291501","journal-title":"Front Med (Lausanne)."},{"issue":"4","key":"6522_CR3","doi-asserted-by":"publisher","first-page":"2251","DOI":"10.3390\/ijms25042251","volume":"25","author":"M Alemany","year":"2024","unstructured":"Alemany M. The metabolic syndrome, a human disease. Int J Mol Sci. 2024;25(4):2251. https:\/\/doi.org\/10.3390\/ijms25042251","journal-title":"Int J Mol Sci."},{"key":"6522_CR4","doi-asserted-by":"publisher","unstructured":"Tsvetkova ES, Romantsova TI, Poluektov MG, et al. The importance of melatonin in the regulation of metabolism, eating behavior, sleep, and the prospects for the use of melatonin drugs for obesity treatment. Obesity and Metabolism. 2021;18(2):112-4. Russian. https:\/\/doi.org\/10.14341\/omet12279","DOI":"10.14341\/omet12279"},{"issue":"1","key":"6522_CR5","doi-asserted-by":"publisher","first-page":"471","DOI":"10.3390\/ijms23010471","volume":"23","author":"G Nikolaev","year":"2021","unstructured":"Nikolaev G, Robeva R, Konakchieva R. Membrane melatonin receptors activated cell signaling in physiology and disease. Int J Mol Sci. 2021;23(1):471. https:\/\/doi.org\/10.3390\/ijms23010471","journal-title":"Int J Mol Sci."},{"issue":"2","key":"6522_CR6","doi-asserted-by":"publisher","first-page":"78","DOI":"10.31373\/ejtcm\/192108","volume":"7","author":"RI Alnaser","year":"2024","unstructured":"Alnaser RI, Alassaf FA, Abed MN. Melatonin as a potential treatment option in diabetes complications. Eur J Transl Clin Med. 2024;7(2):78-91. https:\/\/doi.org\/10.31373\/ejtcm\/192108","journal-title":"Eur J Transl Clin Med."},{"issue":"2","key":"6522_CR7","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1055\/s-0043-57237","volume":"43","author":"M Adori","year":"2023","unstructured":"Adori M, Bhat S, Gramignoli R, et al. Hepatic innervations and nonalcoholic fatty liver disease. Semin Liver Dis. 2023;43(2):149-62. https:\/\/doi.org\/10.1055\/s-0043-57237","journal-title":"Semin Liver Dis."},{"issue":"6","key":"6522_CR8","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.3390\/cells11061021","volume":"11","author":"E Lelou","year":"2022","unstructured":"Lelou E, Corlu A, Nesseler N, et al. The role of catecholamines in pathophysiological liver processes. Cells. 2022;11(6):1021. https:\/\/doi.org\/10.3390\/cells11061021","journal-title":"Cells."},{"issue":"8","key":"6522_CR9","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202306128","volume":"11","author":"W Ren","year":"2024","unstructured":"Ren W, Hua M, Cao F, et al. The Sympathetic-immune milieu in metabolic health and diseases: insights from pancreas, liver, intestine, and adipose tissues. Adv Sci (Weinh). 2024;11(8):e2306128. https:\/\/doi.org\/10.1002\/advs.202306128","journal-title":"Adv Sci (Weinh)."},{"issue":"5","key":"6522_CR10","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1042\/CS20190579","volume":"134","author":"RP Ceddia","year":"2020","unstructured":"Ceddia RP, Collins S. A compendium of G-proteincoupled receptors and cyclic nucleotide regulation of adipose tissue metabolism and energy expenditure. Clin Sci (Lond). 2020;134(5):473-512. https:\/\/doi.org\/10.1042\/CS20190579","journal-title":"Clin Sci (Lond)."},{"issue":"2","key":"6522_CR11","doi-asserted-by":"publisher","first-page":"1108","DOI":"10.1074\/jbc.M307788200","volume":"279","author":"R Burcelin","year":"2004","unstructured":"Burcelin R, Uldry M, Foretz M, et al. Impaired glucose homeostasis in mice lacking the alpha1b-adrenergic receptor subtype. J Biol Chem. 2004;279(2):1108-15. https:\/\/doi.org\/10.1074\/jbc.M307788200","journal-title":"J Biol Chem."},{"key":"6522_CR12","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/594213","volume":"2013","author":"AO Shpakov","year":"2013","unstructured":"Shpakov AO, Derkach KV. The functional state of hormone-sensitive adenylyl cyclase signaling system in diabetes mellitus. J Signal Transduct. 2013;2013:594213. https:\/\/doi.org\/10.1155\/2013\/594213","journal-title":"J Signal Transduct."},{"key":"6522_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1146\/annurev-physiol-060721-092939","volume":"84","author":"S Collins","year":"2022","unstructured":"Collins S. \u03b2-Adrenergic receptors and adipose tissue metabolism: evolution of an old story. Annu Rev Physiol. 2022;84:1-16. https:\/\/doi.org\/10.1146\/annurev-physiol-060721-092939","journal-title":"Annu Rev Physiol."},{"key":"6522_CR14","doi-asserted-by":"publisher","unstructured":"Thotamune W, Ubeysinghe S, Shrestha KK, et al. Optical control of cell-surface and endomembrane-exclusive \u03b2-adrenergic receptor signaling. bioRxiv [Preprint]. 2024. https:\/\/doi.org\/10.1101\/2024.02.14.580335. Update in: J Biol Chem. 2024;300(7):107481. https:\/\/doi.org\/10.1016\/j.jbc.2024.107481","DOI":"10.1101\/2024.02.14.580335"},{"issue":"10","key":"6522_CR15","doi-asserted-by":"publisher","first-page":"2236","DOI":"10.1194\/jlr.M700253-JLR200","volume":"48","author":"J Polak","year":"2007","unstructured":"Polak J, Moro C, Bessi\u00e8re D, et al. Acute exposure to long-chain fatty acids impairs {alpha}2-adrenergic receptormediated antilipolysis in human adipose tissue. J Lipid Res. 2007;48(10):2236-46. https:\/\/doi.org\/10.1194\/jlr.M700253-JLR200","journal-title":"J Lipid Res."},{"key":"6522_CR16","unstructured":"Tapbergenov SO, Tapbergenov TS, Hahn Nelia, et al. Functional and Metabolic Effects of the Sympathetic-Adrenal System and Stress. Moscow, 2019. Russian."},{"key":"6522_CR17","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1038\/s41586-020-2527-y","volume":"583","author":"P Wang","year":"2020","unstructured":"Wang P, Loh KH, Wu M, et al. A leptin-BDNF pathway regulating sympathetic innervation of adipose tissue. Nature. 2020;583:839-44. https:\/\/doi.org\/10.1038\/s41586-020-2527-y","journal-title":"Nature."},{"issue":"4","key":"6522_CR18","doi-asserted-by":"publisher","first-page":"686","DOI":"10.1016\/j.cmet.2017.08.016","volume":"26","author":"H Jiang","year":"2017","unstructured":"Jiang H, Ding X, Cao Y, et al. Dense intra-adipose sympathetic arborizations are essential for cold-induced beiging of mouse white adipose tissue. Cell Metab. 2017;26(4):686-92.e3. https:\/\/doi.org\/10.1016\/j.cmet.2017.08.016","journal-title":"Cell Metab."},{"issue":"3","key":"6522_CR19","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1016\/j.cmet.2021.01.012","volume":"33","author":"K Liu","year":"2021","unstructured":"Liu K, Yang L, Wang G, et al. Metabolic stress drives sympathetic neuropathy within the liver. Cell Metab. 2021;33(3):666-75.e4. https:\/\/doi.org\/10.1016\/j.cmet.2021.01.012","journal-title":"Cell Metab."},{"key":"6522_CR20","doi-asserted-by":"publisher","unstructured":"Willows JW, Blaszkiewicz M, Lamore A, et al. Visualization and analysis of whole depot adipose tissue neural innervation. iScience. 2021;24(10):103127. https:\/\/doi.org\/10.1016\/j.isci.2021.103127","DOI":"10.1016\/j.isci.2021.103127"},{"issue":"21","key":"6522_CR21","doi-asserted-by":"publisher","first-page":"3597","DOI":"10.1016\/j.neuron.2022.10.017","volume":"110","author":"N Martinez-Sanchez","year":"2022","unstructured":"Martinez-Sanchez N, Sweeney O, Sidarta-Oliveira D, et al. The sympathetic nervous system in the 21st century: Neuroimmune interactions in metabolic homeostasis and obesity. Neuron. 2022;110(21):3597-626. https:\/\/doi.org\/10.1016\/j.neuron.2022.10.017","journal-title":"Neuron."},{"key":"6522_CR22","doi-asserted-by":"publisher","unstructured":"Silva A, Caron A. Pathophysiological mechanisms that alter the autonomic brain-liver communication in metabolic diseases. Endocrinology. 2021;162(11):bqab164. https:\/\/doi.org\/10.1210\/endocr\/bqab164","DOI":"10.1210\/endocr\/bqab164"},{"key":"6522_CR23","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.864088","volume":"13","author":"P Busa","year":"2022","unstructured":"Busa P, Kuthati Y, Huang N, et al. New Advances on pathophysiology of diabetes neuropathy and pain management: potential role of melatonin and DPP-4 inhibitors. Front Pharmacol. 2022;13:864088. https:\/\/doi.org\/10.3389\/fphar.2022.864088","journal-title":"Front Pharmacol."},{"issue":"3","key":"6522_CR24","doi-asserted-by":"publisher","first-page":"138","DOI":"10.14710\/jbtr.v7i3.12257","volume":"7","author":"Y Tursinawati","year":"2021","unstructured":"Tursinawati Y, Kartikadewi A, Yuniastuti A, et al. Melatonin, a promising therapeutic for diabetes mellitus and its complications: a narrative review. J Biomed Transl Res [Online]. 2021;7(3):138-45. https:\/\/doi.org\/10.14710\/jbtr.v7i3.12257","journal-title":"J Biomed Transl Res [Online]."},{"issue":"16","key":"6522_CR25","doi-asserted-by":"publisher","first-page":"8677","DOI":"10.3390\/ijms25168677","volume":"25","author":"B de Lux\u00e1n-Delgado","year":"2024","unstructured":"de Lux\u00e1n-Delgado B, Potes Y, Rubio-Gonz\u00e1lez A, et al. Melatonin alleviates liver mitochondrial dysfunction in leptin-deficient mice. Int J Mol Sci. 2024;25(16):8677. https:\/\/doi.org\/10.3390\/ijms25168677","journal-title":"Int J Mol Sci."},{"issue":"2","key":"6522_CR26","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1007\/s10517-017-3949-x","volume":"164","author":"SV Michurina","year":"2017","unstructured":"Michurina SV, Ischenko IY, Arkhipov SA, et al. Melatonin-aluminum oxide-polymethylsiloxane complex on apoptosis of liver cells in a model of obesity and type 2 diabetes mellitus. Bull Exp Biol Med. 2017;164(2):165-9. https:\/\/doi.org\/10.1007\/s10517-017-3949-x","journal-title":"Bull Exp Biol Med."}],"container-title":["Bulletin of Experimental Biology and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10517-025-06522-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10517-025-06522-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10517-025-06522-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,16]],"date-time":"2025-11-16T00:05:08Z","timestamp":1763251508000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10517-025-06522-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["6522"],"URL":"https:\/\/doi.org\/10.1007\/s10517-025-06522-8","relation":{},"ISSN":["0007-4888","1573-8221"],"issn-type":[{"type":"print","value":"0007-4888"},{"type":"electronic","value":"1573-8221"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"3 February 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 February 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 November 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}