{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T07:28:57Z","timestamp":1786778937320,"version":"build-2736575974"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bull Exp Biol Med"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1007\/s10517-026-06706-w","type":"journal-article","created":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T04:33:30Z","timestamp":1785126810000},"page":"723-727","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparative Evaluation of the Effects of Agar and Biofilm Cultures of Francisella tularensis on the Immunological Reactivity of Experimental Animals"],"prefix":"10.1007","volume":"180","author":[{"given":"V. I.","family":"Dubrovina","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T. P.","family":"Starovoitova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. B.","family":"Pyatidesyatnikova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T. A.","family":"Ivanova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. V.","family":"Mazepa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. V.","family":"Naumova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. K.","family":"Syngeeva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. V.","family":"Balakhonov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,27]]},"reference":[{"key":"6706_CR1","unstructured":"Demidova TN, Alesho NA, Mikhailova TV, et al. Tularemia. Moscow, 2020. (In Russ.)."},{"key":"6706_CR2","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1196\/annals.1409.011","volume":"1105","author":"P Keim","year":"2007","unstructured":"Keim P, Johansson A, Wagner DM. Molecular epidemiology, evolution, and ecology of Francisella. Ann NY Acad Sci. 2007;1105:30-66. https:\/\/doi.org\/10.1196\/annals.1409.011","journal-title":"Ann NY Acad Sci."},{"key":"6706_CR3","doi-asserted-by":"publisher","unstructured":"Kudryavtseva TYu, Mokrievich AN. Participation of mosquitoes in the circulation of the tularemia microbe in natural foci. Medicinska\u00e2 Parazitologi\u00e2 i Parazitarnye Bolezni. 2020;(1):34-42. (In Russ.). https:\/\/doi.org\/10.33092\/0025-8326mp2020.1.34-25","DOI":"10.33092\/0025-8326mp2020.1.34-25"},{"key":"6706_CR4","doi-asserted-by":"publisher","unstructured":"Khryanin AA. Microbial biofilms: modern concepts. Antibiotics and Chemotherapy. 2020;65(5-6):70-7. (In Russ.). https:\/\/doi.org\/10.37489\/0235-2990-2020-65-5-6-70-77","DOI":"10.37489\/0235-2990-2020-65-5-6-70-77"},{"issue":"2","key":"6706_CR5","doi-asserted-by":"publisher","first-page":"68","DOI":"10.3103\/S0891416821020026","volume":"36","author":"TS Ilyina","year":"2021","unstructured":"Ilyina TS, Romanova YM. The role of bacterial biofilms in chronic infectious processes and the search for methods to combat them. Mol Gen Microbiol Virol. 2021;36(2):68-78. https:\/\/doi.org\/10.3103\/S0891416821020026","journal-title":"Mol Gen Microbiol Virol."},{"issue":"7","key":"6706_CR6","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1007\/s12033-021-00325-8","volume":"63","author":"F Hemmati","year":"2021","unstructured":"Hemmati F, Rezaee MA, Ebrahimzadeh S, et al. Novel strategies to combat bacterial biofilms. Mol Biotechnol. 2021;63(7):569-86. https:\/\/doi.org\/10.1007\/s12033-021-00325-8","journal-title":"Mol Biotechnol."},{"key":"6706_CR7","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2024.106874","volume":"195","author":"NA Kungwani","year":"2024","unstructured":"Kungwani NA, Panda J, Mishra AK, et al. Combating bacterial biofilms and related drug resistance: Role of phyto-derived adjuvant and nanomaterials. Microb Pathog. 2024;195:106874. https:\/\/doi.org\/10.1016\/j.micpath.2024.106874","journal-title":"Microb Pathog."},{"issue":"1","key":"6706_CR8","doi-asserted-by":"publisher","first-page":"2273567","DOI":"10.1080\/21505594.2023.2273567","volume":"14","author":"Z Guo","year":"2023","unstructured":"Guo Z, Liu M, Zhang D. Potential of phage depolymerase for the treatment of bacterial biofilms. Virulence. 2023;14(1):2273567. https:\/\/doi.org\/10.1080\/21505594.2023.2273567","journal-title":"Virulence."},{"key":"6706_CR9","unstructured":"Kharseeva GG, Frolova YaN, Mironov AYu. Biofilms of pathogenic bacteria: Biological properties and their role in chronization of inflammatory process. Advances in Current Biology. 2015;135(4):346-54. (In Russ.)."},{"key":"6706_CR10","doi-asserted-by":"publisher","unstructured":"Naumova KV, Mazepa AV, Syngeeva AK, et al. Investigation of the ability of Francisella tularensis strains to form biofilms. Sanitarnyj Vra\u010d. 2021;(8):69-74. (In Russ.). https:\/\/doi.org\/10.33920\/med-08-2108-10","DOI":"10.33920\/med-08-2108-10"},{"key":"6706_CR11","unstructured":"Kishkun AA. Guidelines for Laboratory Methods of Diagnostics. Moscow, 2009. (In Russ.)."},{"key":"6706_CR12","doi-asserted-by":"publisher","unstructured":"Shlepotina NM, Peshikova MV, Kolesnikov OL, et al. Modern conceptions about the mechanisms of interaction between biofilm and cellular immunity factors. Journal of Microbiology, Epidemiology and Immunobiology. 2020;97(1):83-90. (In Russ.). https:\/\/doi.org\/10.36233\/0372-9311-2020-97-1-83-90","DOI":"10.36233\/0372-9311-2020-97-1-83-90"}],"container-title":["Bulletin of Experimental Biology and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10517-026-06706-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10517-026-06706-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10517-026-06706-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T07:15:51Z","timestamp":1786778151000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10517-026-06706-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":12,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["6706"],"URL":"https:\/\/doi.org\/10.1007\/s10517-026-06706-w","relation":{},"ISSN":["0007-4888","1573-8221"],"issn-type":[{"value":"0007-4888","type":"print"},{"value":"1573-8221","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"13 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 November 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 July 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}