{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T20:01:48Z","timestamp":1792008108698,"version":"4.4.0"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2008,7,26]],"date-time":"2008-07-26T00:00:00Z","timestamp":1217030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/2.0"},{"start":{"date-parts":[[2008,7,26]],"date-time":"2008-07-26T00:00:00Z","timestamp":1217030400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/2.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Behav Genet"],"published-print":{"date-parts":[[2008,9]]},"DOI":"10.1007\/s10519-008-9219-y","type":"journal-article","created":{"date-parts":[[2008,7,25]],"date-time":"2008-07-25T16:51:55Z","timestamp":1217004715000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["5-HTTLPR and Gender Moderate Changes in Negative Affect Responses to Tryptophan Infusion"],"prefix":"10.1007","volume":"38","author":[{"given":"Beverly H.","family":"Brummett","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher L.","family":"Muller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann L.","family":"Collins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen H.","family":"Boyle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia M.","family":"Kuhn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilene C.","family":"Siegler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Redford B.","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison","family":"Ashley-Koch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,7,26]]},"reference":[{"key":"9219_CR1","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1016\/S0306-4530(01)00054-3","volume":"27","author":"CL Bethea","year":"2002","unstructured":"Bethea CL, Mirkes SJ, Su A, Michelson D (2002) Effects of oral estrogen, raloxifene and arzoxifene on gene expression in serotonin neurons of macaques. Psychoneuroendocrinology 27:431\u2013445. doi:10.1016\/S0306-4530(01)00054-3","journal-title":"Psychoneuroendocrinology"},{"key":"9219_CR2","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/0304-3940(96)12307-7","volume":"204","author":"F Biver","year":"1996","unstructured":"Biver F, Lotstra F, Monclus M, Wikler D, Damhaut P, Mendlewicz J et al (1996) Sex difference in 5HT2 receptor in the living human brain. Neurosci Lett 204:25\u201328. doi:10.1016\/0304-3940(96)12307-7","journal-title":"Neurosci Lett"},{"key":"9219_CR4","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1097\/00041444-200303000-00002","volume":"13","author":"BH Brummett","year":"2003","unstructured":"Brummett BH, Siegler IC, McQuoid DR, Svenson IK, Marchuk DA, Steffens DC (2003) Associations among the NEO Personality Inventory, Revised and the serotonin transporter gene-linked polymorphic region in elders: effects of depression and gender. Psychiatr Genet 13:13\u201318. doi:10.1097\/00041444-200303000-00002","journal-title":"Psychiatr Genet"},{"key":"9219_CR3","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1007\/s10519-007-9172-1","volume":"38","author":"BH Brummett","year":"2008","unstructured":"Brummett BH, Boyle SH, Siegler IC, Kuhn C, Ashley-Koch A, Jonassaint CR et al (2008) Effects of environmental stress and gender on associations among symptoms of depression and the serotonin transporter gene linked polymorphic region (5-HTTLPR). Behav Genet 38:34\u201343. doi:10.1007\/s10519-007-9172-1","journal-title":"Behav Genet"},{"key":"9219_CR5","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1023\/A:1026029723762","volume":"28","author":"AR Burroughs","year":"2003","unstructured":"Burroughs AR, Visscher AW, Haney TL, Efland JR, Barefoot JC, Williams RB et al (2003) Community recruitment process by race, gender, and ses gradient: lessons learned from the community health and stress evaluation (chase) study experience. J Community Health 28:421\u2013437. doi:10.1023\/A:1026029723762","journal-title":"J Community Health"},{"key":"9219_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0165-0173(93)90005-K","volume":"18","author":"F Chaouloff","year":"1993","unstructured":"Chaouloff F (1993) Physiopharmacological interactions between stress hormones and central serotonergic systems. Brain Res Brain Res Rev 18:1\u201332. doi:10.1016\/0165-0173(93)90005-K","journal-title":"Brain Res Brain Res Rev"},{"key":"9219_CR7","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1017\/S0033291700039593","volume":"10","author":"SA Checkley","year":"1980","unstructured":"Checkley SA (1980) Neuroendocrine tests of monoamine function in man: a review of basic theory and its application to the study of depressive illness. Psychol Med 10:35\u201353","journal-title":"Psychol Med"},{"key":"9219_CR8","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1007\/BF02245252","volume":"118","author":"AJ Cleare","year":"1995","unstructured":"Cleare AJ, Bond AJ (1995) The effect of tryptophan depletion and enhancement on subjective and behavioural aggression in normal male subjects. Psychopharmacology 118:72\u201381. doi:10.1007\/BF02245252","journal-title":"Psychopharmacology"},{"key":"9219_CR9","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/S0165-1781(96)03052-1","volume":"69","author":"AJ Cleare","year":"1997","unstructured":"Cleare AJ, Bond AJ (1997) Does central serotonergic function correlate inversely with aggression? A study using D-fenfluramine in healthy subjects. Psychiatry Res 69:89\u201395. doi:10.1016\/S0165-1781(96)03052-1","journal-title":"Psychiatry Res"},{"key":"9219_CR10","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1097\/00004850-199200710-00001","volume":"7","author":"EF Coccaro","year":"1992","unstructured":"Coccaro EF (1992) Impulsive aggression and central serotonergic system function in humans: an example of a dimensional brain-behavior relationship. Int Clin Psychopharmacol 7:3\u201312. doi:10.1097\/00004850-199200710-00001","journal-title":"Int Clin Psychopharmacol"},{"key":"9219_CR11","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1001\/archpsyc.1989.01810070013002","volume":"46","author":"EJ Coccaro","year":"1989","unstructured":"Coccaro EJ, Seiver JL, Klar HM, Maurer G, Cochrane K, Cooper TB et al (1989) Serotonergic studies in patients with affective and personality disorders. Arch Gen Psychiatry 46:587\u2013599","journal-title":"Arch Gen Psychiatry"},{"key":"9219_CR12","first-page":"1980","volume":"46","author":"N Costes","year":"2005","unstructured":"Costes N, Merlet I, Ostrowsky K, Faillenot I, Lavenne F, Zimmer L et al (2005) An 18F-MPPF Pet normative database of 5-HT1a receptor binding in men and women over aging. J Nucl Med 46:1980\u20131989","journal-title":"J Nucl Med"},{"key":"9219_CR13","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1001\/archpsyc.1987.01800230038008","volume":"44","author":"PJ Cowen","year":"1987","unstructured":"Cowen PJ, Charig EM (1987) Neuroendocrine responses to intravenous tryptophan in major depression. Arch Gen Psychiatry 44:958\u2013966","journal-title":"Arch Gen Psychiatry"},{"key":"9219_CR14","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1097\/00041444-200010040-00002","volume":"10","author":"I Du","year":"2000","unstructured":"Du I, Bakish D, Hrdina PD (2000) Gender differences in association between serotonin transporter gene polymorphism and personality traits. Psychiatr Genet 10:159\u2013164","journal-title":"Psychiatr Genet"},{"key":"9219_CR15","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1016\/S0197-0186(98)00064-3","volume":"33","author":"AJ Dunn","year":"1998","unstructured":"Dunn AJ (1998) Brain catecholamine and tryptophan responses to restraint are attenuated by nitric oxide synthase inhibition. Neurochem Int 33:551\u2013557. doi:10.1016\/S0197-0186(98)00064-3","journal-title":"Neurochem Int"},{"key":"9219_CR16","doi-asserted-by":"publisher","first-page":"908","DOI":"10.1038\/sj.mp.4001546","volume":"9","author":"TC Eley","year":"2004","unstructured":"Eley TC, Sugden K, Corsico A, Gregory AM, Sham P, McGuffin P et al (2004) Gene\u2013environment interaction analysis of serotonin system markers with adolescent depression. Mol Psychiatry 9:908\u2013915. doi:10.1038\/sj.mp.4001546","journal-title":"Mol Psychiatry"},{"key":"9219_CR17","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1038\/sj.mp.4000466","volume":"4","author":"JD Flory","year":"1999","unstructured":"Flory JD, Manuck SB, Ferrell RE, Dent KM, Peters DG, Muldoon MF (1999) Neuroticism is not associated with the serotonin transporter (5-HTTLPR) polymorphism. Mol Psychiatry 4:93\u201396. doi:10.1038\/sj.mp.4000466","journal-title":"Mol Psychiatry"},{"key":"9219_CR18","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1176\/ajp.155.10.1332","volume":"155","author":"J Gelernter","year":"1998","unstructured":"Gelernter J, Kranzler H, Caccaro EF, Siever LJ, New AS (1998) Serotonin transporter protein gene polymorphism and personality measures in African American and European American subjects. Am J Psychiatry 155:1332\u20131338","journal-title":"Am J Psychiatry"},{"key":"9219_CR19","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/j.jad.2005.05.007","volume":"87","author":"X Gonda","year":"2005","unstructured":"Gonda X, Juhasz G, Laszik A, Rihmer Z, Bagdy G (2005) Subthreshold depression is linked to the functional polymorphism of the 5HT transporter gene. J Affect Disord 87:291\u2013297. doi:10.1016\/j.jad.2005.05.007","journal-title":"J Affect Disord"},{"key":"9219_CR20","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1007\/s00213-001-0959-0","volume":"160","author":"C Gundlah","year":"2002","unstructured":"Gundlah C, Lu NZ, Betha CL (2002) Ovarian steroid regulation of monoamine oxidase-A and B mRNAs in the macaque dorsal raphe and hypothalamic nuclei. Psychopharmacology 160:271\u2013282. doi:10.1007\/s00213-001-0959-0","journal-title":"Psychopharmacology"},{"key":"9219_CR21","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1001\/archpsyc.1984.01790150088012","volume":"41","author":"GR Heninger","year":"1984","unstructured":"Heninger GR, Charney DS, Sternberg DE (1984) Serotonergic function in depression. Prolactin response to intravenous tryptophan in depressed patients and healthy subjects. Arch Gen Psychiatry 41:398\u2013402","journal-title":"Arch Gen Psychiatry"},{"key":"9219_CR22","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1086\/503850","volume":"78","author":"XZ Hu","year":"2006","unstructured":"Hu XZ, Lipsky RH, Zhu G, Akhtar LA, Traubman J, Greenberg BD et al (2006) Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder. Am J Hum Genet 78:815\u2013826. doi:10.1086\/503850","journal-title":"Am J Hum Genet"},{"key":"9219_CR23","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1001\/archpsyc.63.9.989","volume":"63","author":"N Jacobs","year":"2006","unstructured":"Jacobs N, Kenis G, Peeters F, Derom C, Vlietinck R, van OS J (2006) Stress-related negative affectivity and genetically altered serotonin transporter function. Arch Gen Psychiatry 63:989\u2013996. doi:10.1001\/archpsyc.63.9.989","journal-title":"Arch Gen Psychiatry"},{"key":"9219_CR24","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/S0022-3956(00)00013-3","volume":"34","author":"EG Jonsson","year":"2000","unstructured":"Jonsson EG, Norton N, Gustavsson P, Oreland L, Owen MJ, Sedvall GC (2000) A promoter polymorphism in the monoamine oxidase A gene and its relationships to monoamine metabolite concentrations in CSF of healthy volunteers. J Psychiatr Res 34:239\u2013244. doi:10.1016\/S0022-3956(00)00013-3","journal-title":"J Psychiatr Res"},{"key":"9219_CR25","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1097\/00006199-199801000-00011","volume":"47","author":"TR Knapp","year":"1998","unstructured":"Knapp TR, Kimble LP, Dunbar SB (1998) Distinguishing between the stability of a construct and the stability of an instrument in trait\/state measurement. Nurs Res 47:60\u201362. doi:10.1097\/00006199-199801000-00011","journal-title":"Nurs Res"},{"key":"9219_CR26","doi-asserted-by":"publisher","first-page":"1445","DOI":"10.1176\/appi.ajp.157.9.1445","volume":"157","author":"SG Kornstein","year":"2000","unstructured":"Kornstein SG, Schatzberg AF, Thase ME, Yonkers KA, McCullough JP, Keitner GI et al (2000) Gender differences in treatment response to sertraline versus imipramine in chronic depression. Am J Psychiatry 157:1445\u20131452. doi:10.1176\/appi.ajp.157.9.1445","journal-title":"Am J Psychiatry"},{"key":"9219_CR27","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/S0893-133X(01)00423-7","volume":"27","author":"NZ Lu","year":"2002","unstructured":"Lu NZ, Bethea CL (2002) Ovarian steroid regulation of 5-HT1a receptor binding and G protein activation in female onkeys. Neuropsychopharmacology 27:21\u201324","journal-title":"Neuropsychopharmacology"},{"key":"9219_CR28","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1038\/sj.npp.1395199","volume":"19","author":"SB Manuck","year":"1998","unstructured":"Manuck SB, Flory JD, McCaffery JM, Matthews KA, Mann JJ, Muldoon MF (1998) Aggression, impulsivity, and central nervous system serotonergic responsivity in a nonpatient sample. Neuropsychopharmacology 19:287\u2013299","journal-title":"Neuropsychopharmacology"},{"key":"9219_CR29","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1016\/S0893-133X(01)00369-4","volume":"26","author":"DM Marsh","year":"2002","unstructured":"Marsh DM, Dougherty DM, Moeller FG, Swann AC, Spiga R (2002) Laboratory-measured aggressive behavior of women: acute tryptophan depletion and augmentation. Neuropscyhopharmacology 26:660\u2013671. doi:10.1016\/S0893-133X(01)00369-4","journal-title":"Neuropscyhopharmacology"},{"key":"9219_CR30","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1037\/h0040902","volume":"69","author":"DM McNair","year":"1964","unstructured":"McNair DM, Lorr M (1964) An analysis of mood in neurotics. J Abnorm Soc Psychol 69:620\u2013627. doi:10.1037\/h0040902","journal-title":"J Abnorm Soc Psychol"},{"key":"9219_CR31","doi-asserted-by":"publisher","first-page":"1027","DOI":"10.1016\/0278-5846(94)90128-7","volume":"18","author":"FG Moeller","year":"1994","unstructured":"Moeller FG, Seteinberg JL, Petty F, Fulton M, Cherek DR, Dramer G et al (1994) Serotonin and impulsive\/aggressive behavior in cocain dependent subjects. Prog Neuropsychopharmacol Biol Psychiatry 18:1027\u20131035. doi:10.1016\/0278-5846(94)90128-7","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"9219_CR32","doi-asserted-by":"publisher","first-page":"4823","DOI":"10.1073\/pnas.94.10.5308","volume":"94","author":"S Nishizawa","year":"1997","unstructured":"Nishizawa S, Benkelfat C, Young SN, Leyton M, Mzengeza S, de Montigny C et al (1997) Differences between males and females in rates of serotonin synthesis in human brain. Proc Natl Acad Sci USA 94:4823\u20134824. doi:10.1073\/pnas.94.10.5308","journal-title":"Proc Natl Acad Sci USA"},{"key":"9219_CR33","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1192\/bjp.160.5.643","volume":"160","author":"VO O\u2019Keane","year":"1992","unstructured":"O\u2019Keane VO, Moloney E, O\u2019Neill H, O\u2019Connor A, Smith R, Dian TG (1992) Blunted prolactin responses to d-Fenfluramine in sociopathy: evidence for subsensitivity of central serotonergic function. Br J Psychiatry 160:643\u2013646","journal-title":"Br J Psychiatry"},{"key":"9219_CR34","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/S0306-4522(98)00326-1","volume":"89","author":"M Pecins-Thompson","year":"1999","unstructured":"Pecins-Thompson M, Bethea CL (1999) Ovarian steroid regulation of serotonin-1A autoreceptor messenger rna expression in the dorsal raphe of rhesus macaques. Neuroscience 89:267\u2013277. doi:10.1016\/S0306-4522(98)00326-1","journal-title":"Neuroscience"},{"key":"9219_CR35","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1016\/0278-5846(90)90002-X","volume":"14","author":"LH Price","year":"1990","unstructured":"Price LH, Charney DS, Delgado PL, Goodman WK, Krystal JH, Woods SW et al (1990) Clinical studies of 5-Ht Function using i.v. L-tryptophan. Prog Neuropsychopharmacol Biol Psychiatry 14:459\u2013472. doi:10.1016\/0278-5846(90)90002-X","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"9219_CR36","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1176\/ajp.148.11.1518","volume":"148","author":"LH Price","year":"1991","unstructured":"Price LH, Charney DS, Delgado PL, Heninger GR (1991) Serotonin function and depression: neuroendocrine and mood responses to intravenous l-tryptophan in depressed patients and healthy comparison subjects. Am J Psychiatry 148:1518\u20131525","journal-title":"Am J Psychiatry"},{"key":"9219_CR37","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/j.biopsych.2004.10.010","volume":"57","author":"RA Richell","year":"2005","unstructured":"Richell RA, Deakin JFW, Anderson IM (2005) Effect of acute tryptophan depletion on the response to controllable and uncontrollable noise stress. Biol Psychiatry 57:295\u2013300. doi:10.1016\/j.biopsych.2004.10.010","journal-title":"Biol Psychiatry"},{"key":"9219_CR38","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1017\/S1461145705005936","volume":"9","author":"RL Sjoberg","year":"2006","unstructured":"Sjoberg RL, Nilsson KW, Nordquist N, Ohrvik J, Leppert J, Lindstrom L et al (2006) Development of depression: sex and the interaction between environment and a promoter polymorphism of the serotonin transporter gene. Int J Neuropsychopharmacol 9:443\u2013449. doi:10.1017\/S1461145705005936","journal-title":"Int J Neuropsychopharmacol"},{"key":"9219_CR39","doi-asserted-by":"publisher","first-page":"2035","DOI":"10.1038\/sj.npp.1300510","volume":"29","author":"LJ Smith","year":"2004","unstructured":"Smith LJ, Henderson JA, Abell CW, Bethea CL (2004) Effects of ovarian steroids and raloxifene on proteins that synthesize, transport and degrade serotonin in the raphe region of macaques. Neuropsychopharmacology 29:2035\u20132045. doi:10.1038\/sj.npp.1300510","journal-title":"Neuropsychopharmacology"},{"key":"9219_CR40","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1038\/sj.npp.1300055","volume":"28","author":"S Sobczak","year":"2003","unstructured":"Sobczak S, Honig A, Schmitt JAJ, Riedel WJ (2003) Pronounced cognitive deficits following an intravenous L-Tryptophan challenge in first-degree relatives of bipolar patients compared to healthy controls. Neuropscyhopharmacology 28:711\u2013719. doi:10.1038\/sj.npp.1300055","journal-title":"Neuropscyhopharmacology"},{"issue":"3","key":"9219_CR41","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1016\/j.biopsych.2005.07.014","volume":"59","author":"PG Surtees","year":"2006","unstructured":"Surtees PG, Wainwright NWJ, Willis-Owne SAG, Luben R, Day NE, Flint J (2006) Social adversity, the serotonin transporter (5-HTTLPR) polymorphism and major depressive disorder. Biol Psychiatry 59(3):224\u2013229","journal-title":"Biol Psychiatry"},{"key":"9219_CR42","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/S0165-0327(00)00209-3","volume":"64","author":"AJW Van der Does","year":"2001","unstructured":"Van der Does AJW (2001) The effects of tryptophan depletion on mood and psychiatric symptoms. J Affect Disord 64:107\u2013119. doi:10.1016\/S0165-0327(00)00209-3","journal-title":"J Affect Disord"},{"key":"9219_CR43","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1097\/00006842-200103000-00016","volume":"63","author":"RB Williams","year":"2001","unstructured":"Williams RB, Marchuk DA, Gadde KM, Barefoot JC, Grichnik K, Helms MJ et al (2001) Central nervous system serotonin function and cardiovascular responses to stress. Psychosom Med 63:300\u2013305","journal-title":"Psychosom Med"},{"key":"9219_CR44","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1038\/sj.npp.1300054","volume":"28","author":"RB Williams","year":"2003","unstructured":"Williams RB, Marchuk DA, Gadde KM, Barefoot JC, Grichnik K, Helms MJ et al (2003) Serotonin-related gene polymorphisms and central nervous system serotonin function. Neuropsychopharmacology 28:533\u2013541. doi:10.1038\/sj.npp.1300054","journal-title":"Neuropsychopharmacology"},{"key":"9219_CR45","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1016\/0024-3205(93)90696-Z","volume":"53","author":"LN Yatham","year":"1993","unstructured":"Yatham LN, Steiner M (1993) Neuroendocrine probes of serotonergic function: a critical review. Life Sci 53:447\u2013463. doi:10.1016\/0024-3205(93)90696-Z","journal-title":"Life Sci"}],"updated-by":[{"DOI":"10.1007\/s10519-020-10030-y","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2020,12,16]],"date-time":"2020-12-16T00:00:00Z","timestamp":1608076800000}}],"container-title":["Behavior Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10519-008-9219-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10519-008-9219-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10519-008-9219-y.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10519-008-9219-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,31]],"date-time":"2021-08-31T20:15:49Z","timestamp":1630440949000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10519-008-9219-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7,26]]},"references-count":45,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,9]]}},"alternative-id":["9219"],"URL":"https:\/\/doi.org\/10.1007\/s10519-008-9219-y","relation":{},"ISSN":["0001-8244","1573-3297"],"issn-type":[{"value":"0001-8244","type":"print"},{"value":"1573-3297","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,7,26]]},"assertion":[{"value":"13 May 2008","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 July 2008","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 July 2008","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 December 2020","order":4,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":5,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s10519-020-10030-y","URL":"https:\/\/doi.org\/10.1007\/s10519-020-10030-y","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"476"}}