{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T02:02:45Z","timestamp":1771466565731,"version":"3.50.1"},"reference-count":63,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2017,6,2]],"date-time":"2017-06-02T00:00:00Z","timestamp":1496361600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Department of Biotechnology , Ministry of Science and Technology (IN)","award":[": 102\/IFD\/SAN\/5407\/2011-2012 Dated 28.3.2012"],"award-info":[{"award-number":[": 102\/IFD\/SAN\/5407\/2011-2012 Dated 28.3.2012"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Biogerontology"],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.1007\/s10522-017-9711-y","type":"journal-article","created":{"date-parts":[[2017,6,2]],"date-time":"2017-06-02T08:56:56Z","timestamp":1496393816000},"page":"615-630","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Daily chronomics of proteomic profile in aging and rotenone-induced Parkinson\u2019s disease model in male Wistar rat and its modulation by melatonin"],"prefix":"10.1007","volume":"18","author":[{"given":"Anita","family":"Jagota","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ushodaya","family":"Mattam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,6,2]]},"reference":[{"key":"9711_CR1","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S0166-4328(02)00180-8","volume":"136","author":"M Alam","year":"2002","unstructured":"Alam M, Schmidt WJ (2002) Rotenone destroys dopaminergic neurons and induces parkinsonian symptoms in rats. Behav Brain Res 136:317\u2013324","journal-title":"Behav Brain Res"},{"key":"9711_CR2","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0306-4522(01)00285-8","volume":"106","author":"F Aujard","year":"2001","unstructured":"Aujard F, Herzog ED, Block GD (2001) Circadian rhythms in firing rate of individual suprachiasmatic nucleus neurons from adult and middle aged mice. Neuroscience 106:255\u2013261","journal-title":"Neuroscience"},{"key":"9711_CR3","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1007\/s00335-016-9639-6","volume":"27","author":"G Banks","year":"2016","unstructured":"Banks G, Nolan PM, Peirson SN (2016) Reciprocal interactions between circadian clocks and aging. Mamm Genome 27:332\u2013340","journal-title":"Mamm Genome"},{"key":"9711_CR4","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1038\/35072550","volume":"2","author":"MF Beal","year":"2001","unstructured":"Beal MF (2001) Experimental models of Parkinson\u2019s disease. Nat Rev Neurosci 2:325\u2013334","journal-title":"Nat Rev Neurosci"},{"key":"9711_CR5","doi-asserted-by":"publisher","DOI":"10.1038\/srep17397","author":"A Bezawork-Geleta","year":"2015","unstructured":"Bezawork-Geleta A, Brodie EJ, Dougan DA, Truscott KN (2015) LON is the master protease that protects against protein aggregation in human mitochondria through direct degradation of misfolded proteins. Sci Rep. doi: 10.1038\/srep17397","journal-title":"Sci Rep"},{"key":"9711_CR6","first-page":"491","volume-title":"Neurodegenerative disease","author":"R Cabezas","year":"2013","unstructured":"Cabezas R, Avila MF, Torrente D, El-Bach\u00e1 RS, Morales L, Gonzalez J, Barreto GE (2013) Astrocytes role in Parkinson: a double-edged sword. In: Kishore U (ed) Neurodegenerative disease. INTECH Open Access Publisher, Rijeka, pp 491\u2013517"},{"key":"9711_CR7","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1111\/j.1600-079X.2011.00962.x","volume":"52","author":"DP Cardinali","year":"2012","unstructured":"Cardinali DP, Srinivasan V, Brzezinski A, Brown GM (2012) Melatonin and its analogs in insomnia and depression. J Pineal Res 52:365\u2013375","journal-title":"J Pineal Res"},{"key":"9711_CR9","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/j.neuron.2007.10.019","volume":"56","author":"S Chauvet","year":"2007","unstructured":"Chauvet S, Cohen S, Yoshida Y, Fekrane L, Livet J, Gayet O, Segu L, Buhot MC, Jessell TM, Henderson CE, Mann F (2007) Gating of Sema3E\/PlexinD1 signaling by neuropilin-1 switches axonal repulsion to attraction during brain development. Neuron 56:807\u2013822","journal-title":"Neuron"},{"key":"9711_CR10","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/j.neuron.2007.05.017","volume":"54","author":"HY Cheng","year":"2007","unstructured":"Cheng HY, Papp JW, Varlamova O, Dziema H, Russell B, Curfman JP, Nakazawa T, Shimizu K, Okamura H, Impey S, Obrietan K (2007) microRNA modulation of circadian-clock period and entrainment. Neuron 54:813\u2013829","journal-title":"Neuron"},{"key":"9711_CR75","doi-asserted-by":"crossref","first-page":"2626","DOI":"10.1210\/endo-122-6-2626","volume":"122","author":"IR Cohen","year":"1988","unstructured":"Cohen IR, Wise PM (1988) Age-related changes in the diurnal rhythm of serotonin turnover in microdissected brain areas of estradiol-treated ovariectomized rats. Endocrinology 122:2626\u20132633","journal-title":"Endocrinology"},{"key":"9711_CR12","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/S0896-6273(03)00568-3","volume":"39","author":"W Dauer","year":"2003","unstructured":"Dauer W, Przedborski S (2003) Parkinson\u2019s disease: mechanisms and models. Neuron 39:889\u2013909","journal-title":"Neuron"},{"key":"9711_CR13","doi-asserted-by":"crossref","first-page":"2031","DOI":"10.1016\/j.cub.2009.10.024","volume":"19","author":"MJ Deery","year":"2009","unstructured":"Deery MJ, Maywood ES, Chesham JE, Sl\u00e1dek M, Karp NA, Green EW, Charles PD, Reddy AB, Kyriacou CP, Lilley KS, Hastings MH (2009) Proteomic analysis reveals the role of synaptic vesicle cycling in sustaining the suprachiasmatic circadian clock. Curr Biol 19:2031\u20132036","journal-title":"Curr Biol"},{"key":"9711_CR14","doi-asserted-by":"crossref","first-page":"5237","DOI":"10.1002\/j.1460-2075.1993.tb06219.x","volume":"12","author":"A Gallusser","year":"1993","unstructured":"Gallusser A, Kirchhausen T (1993) The beta 1 and beta 2 subunits of the AP complexes are the clathrin coat assembly components. EMBO J 12:5237\u20136244","journal-title":"EMBO J"},{"key":"9711_CR15","doi-asserted-by":"crossref","first-page":"4903","DOI":"10.1093\/emboj\/18.18.4903","volume":"18","author":"NB Ghyselinck","year":"1999","unstructured":"Ghyselinck NB, B\u00e5vik C, Sapin V, Mark M, Bonnier D, Hindelang C, Dierich A, Nilsson CB, H\u00e5kansson H, Sauvant P, Aza\u00efs-Braesco V, Frasson M, Picaud S, Chambon P (1999) Cellular retinol-binding protein I is essential for vitamin A homeostasis. EMBO J 18:4903\u20134914","journal-title":"EMBO J"},{"key":"9711_CR78","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.yfrne.2014.02.002","volume":"35","author":"GE Gillies","year":"2014","unstructured":"Gillies GE, Pienaar IS, Vohra S, Qamhawi Z (2014) Sex differences in Parkinson's disease. Front Neuroendocrinol 35:370\u2013384","journal-title":"Front Neuroendocrinol"},{"key":"9711_CR72","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/0091-3057(80)90254-3","volume":"13","author":"TG Heffner","year":"1980","unstructured":"Heffner TG, Hartman JA, Seiden LS (1980) A rapid method for the regional dissection of the rat brain. Pharmacol Biochem Behav 13:453-456","journal-title":"Pharmacol Biochem Behav"},{"issue":"10","key":"9711_CR16","doi-asserted-by":"crossref","first-page":"e46155","DOI":"10.1371\/journal.pone.0046155","volume":"7","author":"G Hilgen","year":"2012","unstructured":"Hilgen G, Huebner AK, Tanimoto N, Sothilingam V, Seide C, Garrido MG, Schmidt KF, Seeliger MW, L\u00f6wel S, Weiler R, H\u00fcbner CA, Dedek K (2012) Lack of the sodium-driven chloride bicarbonate exchanger NCBE impairs visual function in the mouse retina. PLoS ONE 7(10):e46155","journal-title":"PLoS ONE"},{"key":"9711_CR19","doi-asserted-by":"crossref","first-page":"9477","DOI":"10.1016\/S0021-9258(17)44692-8","volume":"258","author":"Y Ikeda","year":"1983","unstructured":"Ikeda Y, Tanaka K (1983) Purification and characterization of 2-methyl-branched chain acyl coenzyme A dehydrogenase, an enzyme involved in the isoleucine and valine metabolism, from rat liver mitochondria. J Biol Chem 258:9477\u20139487","journal-title":"J Biol Chem"},{"key":"9711_CR20","first-page":"415","volume":"19","author":"A Jagota","year":"2005","unstructured":"Jagota A (2005) Aging and sleep disorders. Indian J Gerontol 19:415\u2013424","journal-title":"Indian J Gerontol"},{"key":"9711_CR21","first-page":"275","volume":"71","author":"A Jagota","year":"2006","unstructured":"Jagota A (2006) Suprachiasmatic nucleus: the center for circadian timing system in mammals. Proc Indian Natl Sci Acad 71:275\u2013288","journal-title":"Proc Indian Natl Sci Acad"},{"key":"9711_CR22","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/978-94-007-5237-5_8","volume-title":"Brain aging and therapeutic interventions","author":"A Jagota","year":"2012","unstructured":"Jagota A (2012) Age induced alterations in biological clock: therapeutic effects of melatonin. In: Thakur MK, Rattan SI (eds) Brain aging and therapeutic interventions. Springer, Dordrecht, pp 111\u2013129"},{"key":"9711_CR23","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1007\/s10522-008-9132-z","volume":"9","author":"A Jagota","year":"2008","unstructured":"Jagota A, Kalyani D (2008) Daily serotonin rhythms in rat brain during postnatal development and aging. Biogerontology 9:229\u2013234","journal-title":"Biogerontology"},{"key":"9711_CR24","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/s10522-009-9248-9","volume":"11","author":"A Jagota","year":"2010","unstructured":"Jagota A, Kalyani D (2010) Effect of melatonin on age induced changes in daily serotonin rhythms in suprachiasmatic nucleus of male Wistar rat. Biogerontology 11:299\u2013308","journal-title":"Biogerontology"},{"key":"9711_CR25","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1007\/s10571-007-9203-8","volume":"27","author":"A Jagota","year":"2007","unstructured":"Jagota A, Reddy MY (2007) The effect of curcumin on ethanol induced changes in suprachiasmatic nucleus (SCN) and pineal. Cell Mol Neurobiol 27:997\u20131006","journal-title":"Cell Mol Neurobiol"},{"key":"9711_CR26","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0006-8993(99)01226-3","volume":"825","author":"A Jagota","year":"1999","unstructured":"Jagota A, Olcese J, Rao H, Gupta PD (1999) Recognition of light in variable photoperiods by anophthalmic mutant rats. Brain Res 825:95\u2013103","journal-title":"Brain Res"},{"key":"9711_CR27","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1038\/73943","volume":"3","author":"A Jagota","year":"2000","unstructured":"Jagota A, de la Iglesia HO, Schwartz WJ (2000) Morning and evening circadian oscillations in the suprachiasmatic nucleus in vitro. Nat Neurosci 3:372\u2013376","journal-title":"Nat Neurosci"},{"key":"9711_CR28","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1016\/j.exger.2004.04.012","volume":"39","author":"M Karasek","year":"2004","unstructured":"Karasek M (2004) Melatonin, human aging, and age-related diseases. Exp Gerontol 39:1723\u20131729","journal-title":"Exp Gerontol"},{"key":"9711_CR29","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1159\/000048238","volume":"75","author":"H Khaldy","year":"2002","unstructured":"Khaldy H, Le\u00f3n J, Escames G, Bikjdaouene L, Garc\u00eda JJ, Acu\u00f1a-Castroviejo D (2002) Circadian rhythms of dopamine and dihydroxyphenyl acetic acid in the mouse striatum: effects of pinealectomy and of melatonin treatment. Neuroendocrinology 75:201\u2013208","journal-title":"Neuroendocrinology"},{"key":"9711_CR31","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1111\/j.1471-4159.2009.06223.x","volume":"110","author":"GYP Ko","year":"2009","unstructured":"Ko GYP, Shi L, Ko ML (2009) Circadian regulation of ion channels and their functions. J Neurochem 110:1150\u20131169","journal-title":"J Neurochem"},{"key":"9711_CR32","doi-asserted-by":"crossref","first-page":"1868","DOI":"10.1101\/gad.1432206","volume":"20","author":"RV Kondratov","year":"2006","unstructured":"Kondratov RV, Kondratova AA, Gorbacheva VY, Vykhovanets OV, Antoch MP (2006) Early aging and age-related pathologies in mice deficient in BMAL1, the core component of the circadianclock. Genes Dev 20:1868\u20131873","journal-title":"Genes Dev"},{"key":"9711_CR33","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1038\/nrn3208","volume":"13","author":"AA Kondratova","year":"2012","unstructured":"Kondratova AA, Kondratov RV (2012) The circadian clock and pathology of the ageing brain. Nat Rev Neurosci 13:325\u2013335","journal-title":"Nat Rev Neurosci"},{"key":"9711_CR74","doi-asserted-by":"crossref","first-page":"22320","DOI":"10.3390\/ijms151222320","volume":"15","author":"FC Koyama","year":"2014","unstructured":"Koyama FC, Azevedo MF, Budu A, Cha abarti D, Garcia CR (2014) Melatonin-induced temporal up-regulation of gene expression related to ubiquitin\/proteasome system (UPS) in the human malaria parasite Plasmodium falciparum. Int J Mol Sci 15:22320\u201322330","journal-title":"Int J Mol Sci"},{"key":"9711_CR76","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0006-8993(03)03441-3","volume":"990","author":"K Krajnak","year":"2003","unstructured":"Krajnak K, Rosewell KL, Duncan MJ, Wise PM (2003) Aging, estradiol and time of day differentially affect serotonin transporter binding in the central nervous system of female rats. Brain Res 990:87\u201394","journal-title":"Brain Res"},{"key":"9711_CR34","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1021\/pr300605p","volume":"12","author":"JE Lee","year":"2013","unstructured":"Lee JE, Zamdborg L, Bruce R, Southey BR, Atkins N Jr, Mitchell JW, Li M, Gillette MU, Kelleher NL, Sweedler JV (2013) Quantitative peptidomics for discovery of circadian-related peptides from the rat suprachiasmatic nucleus. J Proteom Res 12:585\u2013593","journal-title":"J Proteom Res"},{"key":"9711_CR36","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1007\/s10522-012-9396-1","volume":"13","author":"PK Manikonda","year":"2012","unstructured":"Manikonda PK, Jagota A (2012) Melatonin administration differentially affects age-induced alterations in daily rhythms of lipid peroxidation and antioxidant enzymes in male rat liver. Biogerontology 13:511\u2013524","journal-title":"Biogerontology"},{"key":"9711_CR37","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/s10522-014-9495-2","volume":"3","author":"U Mattam","year":"2014","unstructured":"Mattam U, Jagota A (2014) Differential role of melatonin in restoration of age-induced alterations in daily rhythms of expression of various clock genes in suprachiasmatic nucleus of male Wistar rats. Biogerontology 3:257\u2013268","journal-title":"Biogerontology"},{"key":"9711_CR38","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s10522-014-9541-0","volume":"16","author":"U Mattam","year":"2015","unstructured":"Mattam U, Jagota A (2015) Daily rhythms of serotonin metabolism and the expression of clock genes in suprachiasmatic nucleus of rotenone-induced Parkinson\u2019s disease male Wistar rat model and effect of melatonin administration. Biogerontology 16:109\u2013123","journal-title":"Biogerontology"},{"key":"9711_CR42","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1002\/mas.20237","volume":"29","author":"M Moller","year":"2010","unstructured":"Moller M, Lund-Andersen C, Rovsing L, Sparre T, Bache N, Roepstorff P, Vorum H (2010) Proteomics of the photo-neuroendocrine circadian system of the brain. Mass Spectrom Rev 29:313\u2013325","journal-title":"Mass Spectrom Rev"},{"key":"9711_CR43","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1002\/1615-9861(200111)1:11<1359::AID-PROT1359>3.0.CO;2-Q","volume":"1","author":"E Mortz","year":"2001","unstructured":"Mortz E, Krogh TN, Vorum H, G\u00f6rg A (2001) Improved silver staining protocols for high sensitivity protein identification using matrix-assisted laser desorption\/ionization-time of flight analysis. Proteomics 1:1359\u20131363","journal-title":"Proteomics"},{"key":"9711_CR45","doi-asserted-by":"crossref","first-page":"10201","DOI":"10.1523\/JNEUROSCI.0451-11.2011","volume":"31","author":"JT Nakamura","year":"2011","unstructured":"Nakamura JT, Nakamura W, Yamazaki S, Kudo T, Cutler T, Colwell CS, Block GD (2011) Age-related decline in circadian output. J Neurosci 31:10201\u201310205","journal-title":"J Neurosci"},{"key":"9711_CR46","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1177\/0748730408316998","volume":"23","author":"M Palomba","year":"2008","unstructured":"Palomba M, Nygard M, Florenzano F, Bertini G, Kristenssion K, Bentivoglio M (2008) Decline of the presynaptic network, including GABAergic terminals, in the aging suprachiasmatic nucleus of the mouse. J Biol Rhythms 23:220\u2013231","journal-title":"J Biol Rhythms"},{"key":"9711_CR47","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/s12640-012-9337-4","volume":"23","author":"SR Pandi-Perumal","year":"2013","unstructured":"Pandi-Perumal SR, BaHammam AS, Brown GM, Spence DW, Bharti VK, Kaur C, Hardeland R, Cardinali DP (2013) Melatonin antioxidative defense: therapeutical implications for aging and neurodegenerative processes. Neurotox Res 23:267\u2013300","journal-title":"Neurotox Res"},{"key":"9711_CR48","doi-asserted-by":"crossref","first-page":"3335","DOI":"10.1101\/gad.490608","volume":"22","author":"S Parrinello","year":"2008","unstructured":"Parrinello S, Noon LA, Harrisingh MC, Digby PW, Rosenberg LH, Cremona CA, Echave P, Flanagan AM, Parada LF, Lloyd AC (2008) NF1 loss disrupts Schwann cell-axonal interactions: a novel role for semaphorin 4F. Genes Dev 22:3335\u20133348","journal-title":"Genes Dev"},{"key":"9711_CR49","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1159\/000058544","volume":"11","author":"D Pazo","year":"2002","unstructured":"Pazo D, Cardinali DP, Cano P, Reyes Toso CA, Esquifino AI (2002) Age-related changes in 24-h rhythms of norepinephrine content and serotonin turnover in rat pineal gland: effect of melatonin treatment. Neurosignals 11:81\u201387","journal-title":"Neurosignals"},{"key":"9711_CR51","first-page":"65","volume-title":"Proteomics\u2014human diseases and protein functions","author":"PS Podobed","year":"2012","unstructured":"Podobed PS, Kirby GM, Martino TA (2012) Circadian proteomics and its unique advantage for discovery of biomarkers of heart disease. In: Man TK (ed) Proteomics\u2014human diseases and protein functions. INTECH Open Access Publisher, Rijeka, pp 65\u201388"},{"key":"9711_CR52","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1385\/ENDO:27:2:201","volume":"27","author":"B Poeggeler","year":"2005","unstructured":"Poeggeler B (2005) Melatonin, aging, and age-related diseases: perspectives for prevention, intervention, and therapy. Endocrine 27:201\u2013212","journal-title":"Endocrine"},{"key":"9711_CR54","volume-title":"Oxidative stress and neurodegenerative disorders","author":"GA Qureshi","year":"2007","unstructured":"Qureshi GA, Parvez SH (2007) Oxidative stress and neurodegenerative disorders. Elsevier, Oxford"},{"key":"9711_CR55","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1517\/17460441.2012.677430","volume":"7","author":"SI Rattan","year":"2012","unstructured":"Rattan SI (2012) Rationale and methods of discovering hormetins as drugs for healthy ageing. Expert Opin Drug Discov 7:439\u2013448","journal-title":"Expert Opin Drug Discov"},{"key":"9711_CR56","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/s10522-014-9494-3","volume":"3","author":"VD Reddy","year":"2014","unstructured":"Reddy VD, Jagota A (2014) Effect of restricted feeding on nocturnality and daily leptin rhythms in OVLT in aged male Wistar rats. Biogerontology 3:245\u2013256","journal-title":"Biogerontology"},{"key":"9711_CR57","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/s10522-014-9545-9","volume":"16","author":"MY Reddy","year":"2015","unstructured":"Reddy MY, Jagota A (2015) Melatonin has differential effects on age-induced stoichiometric changes in daily chronomics of serotonin metabolism in SCN of male Wistar rats. Biogerontology 16:285\u2013302","journal-title":"Biogerontology"},{"key":"9711_CR58","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1152\/physiol.00011.2014","volume":"29","author":"RJ Reiter","year":"2014","unstructured":"Reiter RJ, Tan DX, Galano A (2014) Melatonin: exceeding expectations. Physiology 29:325\u2013333","journal-title":"Physiology"},{"key":"9711_CR61","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/0003-2697(73)90217-0","volume":"56","author":"W Schaffner","year":"1973","unstructured":"Schaffner W, Weissmann C (1973) A rapid, sensitive, and specific method for the determination of protein in dilute solution. Anal Biochem 56:502\u2013514","journal-title":"Anal Biochem"},{"issue":"25","key":"9711_CR62","doi-asserted-by":"crossref","first-page":"14440","DOI":"10.1073\/pnas.93.25.14440","volume":"93","author":"A Shevchenko","year":"1996","unstructured":"Shevchenko A, Jensen ON, Podtelejnikov AV, Sagliocco F, Wilm M, Vorm O, Mortensen P, Shevchenko A, Boucherie H, Mann M (1996) Linking genome and proteome by mass spectrometry: large-scale identification of yeast proteins from two dimensional gels. Proc Natl Acad Sci USA 93(25):14440\u201314445","journal-title":"Proc Natl Acad Sci USA"},{"key":"9711_CR63","doi-asserted-by":"crossref","first-page":"21580","DOI":"10.1074\/jbc.M109.012112","volume":"284","author":"R Shirakawa","year":"2009","unstructured":"Shirakawa R, Fukai S, Kawato M, Higashi T, Kondo H, Ikeda T, Nakayama E, Okawa K, Nureki O, Kimura T, Kita T, Horiuchi H (2009) Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases. J Biol Chem 284:21580\u201321588","journal-title":"J Biol Chem"},{"key":"9711_CR77","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1210\/er.2002-0017","volume":"26","author":"RG Smith","year":"2005","unstructured":"Smith RG, Betancourt L, Sun Y (2005) Molecular endocrinology and physiology of the aging central nervous system. Endoc Rev 26:203\u2013250","journal-title":"Endoc Rev"},{"key":"9711_CR64","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1006\/bbrc.1999.0265","volume":"255","author":"H Tanahashi","year":"1999","unstructured":"Tanahashi H, Tabira T (1999) X11L2, a new member of the X11 Protein family, interacts with Alzheimer\u2019s \u03b2-amyloid precursor protein. Biochem Biophys Res Commun 255:663\u2013667","journal-title":"Biochem Biophys Res Commun"},{"key":"9711_CR66","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/s00441-004-0937-z","volume":"318","author":"NV Uversky","year":"2004","unstructured":"Uversky NV (2004) Neurotoxicant \u2013induced animal modes of Parkinson\u2019s disease: understanding the role of rotenone, maneb and paraquat in neurodegeneration. Cell Tissue Res 318:225\u2013241","journal-title":"Cell Tissue Res"},{"key":"9711_CR67","doi-asserted-by":"publisher","first-page":"e0127075","DOI":"10.1371\/journal.pone.0127075","volume":"10","author":"KC Dycke Van","year":"2015","unstructured":"Van Dycke KC, Pennings JL, van Oostrom CT, van Kerkhof LW, van Steeg H, van der Horst GT, Rodenburg W (2015) Biomarkers for circadian rhythm disruption independent of time of day. PLoS ONE 10:e0127075. doi: 10.1371\/journal.pone.0127075","journal-title":"PLoS ONE"},{"key":"9711_CR68","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1111\/j.1474-9726.2007.00329.x","volume":"6","author":"VA Vernace","year":"2007","unstructured":"Vernace VA, Schmidt-Glenewinkel T, Figueiredo-Pereira ME (2007) Aging and regulated protein degradation: who has the UPPer hand? Aging Cell 6:599\u2013606","journal-title":"Aging Cell"},{"key":"9711_CR69","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1007\/s10522-016-9656-6","volume":"17","author":"C Vinod","year":"2016","unstructured":"Vinod C, Jagota A (2016) Daily NO rhythms in peripheral clocks in aging male Wistar rats: protective effects of exogenous melatonin. Biogerontology 17:859\u2013871","journal-title":"Biogerontology"},{"key":"9711_CR70","doi-asserted-by":"publisher","DOI":"10.1007\/s10522-017-9687-7","author":"C Vinod","year":"2017","unstructured":"Vinod C, Jagota A (2017) Daily Socs1 rhythms alter with aging differentially in peripheral clocks in male Wistar rats: therapeutic effects of melatonin. Biogerontology. doi: 10.1007\/s10522-017-9687-7","journal-title":"Biogerontology"},{"key":"9711_CR71","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1113\/jphysiol.2001.012743","volume":"537","author":"S Wagner","year":"2001","unstructured":"Wagner S, Sagiv N, Yarom Y (2001) GABA-induced current and circadian regulation of chloride in neurones of the rat suprachiasmatic nucleus. J Physiol 537:853\u2013869","journal-title":"J Physiol"},{"key":"9711_CR73","doi-asserted-by":"crossref","first-page":"35486","DOI":"10.1074\/jbc.C000456200","volume":"275","author":"CZ Wang","year":"2000","unstructured":"Wang CZ, Yano H, Nagashima K, Seino S (2000) The Na+-driven Cl-\/HCO3- exchanger. Cloning, tissue distribution, and functional characterization. J Biol Chem 275:35486\u201335490","journal-title":"J Biol Chem"}],"container-title":["Biogerontology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10522-017-9711-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10522-017-9711-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10522-017-9711-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T02:32:04Z","timestamp":1659061924000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10522-017-9711-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,2]]},"references-count":63,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["9711"],"URL":"https:\/\/doi.org\/10.1007\/s10522-017-9711-y","relation":{},"ISSN":["1389-5729","1573-6768"],"issn-type":[{"value":"1389-5729","type":"print"},{"value":"1573-6768","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,2]]}}}