{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T13:24:00Z","timestamp":1767705840892,"version":"3.37.3"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T00:00:00Z","timestamp":1625443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T00:00:00Z","timestamp":1625443200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Biochem Genet"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1007\/s10528-021-10099-y","type":"journal-article","created":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T14:03:42Z","timestamp":1625493822000},"page":"336-350","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The Effect of B9 and B12 Vitamins Deficiency on Hypomethylation of MMP-9 gene Promoter Among Women With Preterm Parturition"],"prefix":"10.1007","volume":"60","author":[{"given":"Moeini","family":"N","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Momeni","family":"AM","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zargar","family":"M","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abotorabi","family":"Sh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Habibi Nozari","family":"F","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7653-8689","authenticated-orcid":false,"given":"Moghbelinejad","family":"S","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,7,5]]},"reference":[{"key":"10099_CR1","doi-asserted-by":"publisher","first-page":"e37513","DOI":"10.7554\/eLife.37513","volume":"7","author":"J Amanda","year":"2018","unstructured":"Amanda J, Christopher MV, Rachel AJ, Christina AD, Luis BB, Timothy E, Reddy JT (2018) Genome-wide quantification of the effects of DNA methylation on human gene regulation. Elife 7:e37513","journal-title":"Elife"},{"key":"10099_CR2","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1097\/00004703-200512000-00008","volume":"26","author":"GP Aylward","year":"2005","unstructured":"Aylward GP (2005) Neurodevelopmental outcomes of infants born prema turely. J Dev Behav Pediatr 26:427\u2013440","journal-title":"J Dev Behav Pediatr"},{"key":"10099_CR3","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1002\/mrd.21296","volume":"78","author":"P Chavan-Gautam","year":"2011","unstructured":"Chavan-Gautam P, Sundari D, Pisal H, Nimbargi V, Mehendale S, Joshi S (2011) Gestation-dependent changes in human placental global DNA methylation levels. Mol Reprod Dev 78:150","journal-title":"Mol Reprod Dev"},{"key":"10099_CR4","doi-asserted-by":"publisher","first-page":"a023143","DOI":"10.1101\/cshperspect.a023143","volume":"5","author":"RN Errol","year":"2015","unstructured":"Errol RN, Elizabeth AB, Victoria VS, Michelle AW, Mark P, Joong SP, Vikki MA (2015) Molecular Regulation of Parturition: The Role of the Decidual Clock. Cold Spring Harb Perspect Med 5:a023143","journal-title":"Cold Spring Harb Perspect Med"},{"key":"10099_CR5","doi-asserted-by":"publisher","first-page":"5107","DOI":"10.1128\/MCB.20.14.5107-5118.2000","volume":"20","author":"N Fujita","year":"2000","unstructured":"Fujita N, Shimotake N, Ohki I, Chiba T, Saya H, Shirakawa M, Nakao M (2000) Mechanism of transcriptional regulation by methyl-CpG binding protein MBD1. Mol Cell Biol 20:5107\u20135118","journal-title":"Mol Cell Biol"},{"key":"10099_CR6","doi-asserted-by":"publisher","first-page":"646","DOI":"10.3389\/fgene.2018.00646","volume":"11","author":"J Gao","year":"2018","unstructured":"Gao J, Yi H, Tang X, Feng X, Yu M, Sha W, Wang X, Zhang X, Zhang X (2018) DNA methylation and gene expression of Matrix metalloproteinase 9 gene in deficit and non-deficit schizophrenia. Front Genet 11:646","journal-title":"Front Genet"},{"key":"10099_CR7","doi-asserted-by":"publisher","first-page":"4","DOI":"10.3390\/ijms20040973","volume":"20","author":"A Geoffroy","year":"2019","unstructured":"Geoffroy A, Saber-Cherif L, Pouri\u00e9 G, Helle D, Umoret R, Gu\u00e9ant JL, Bossenmeyer-Pouri\u00e9 C, Daval JL (2019) Developmental Impairments in a rat model of methyl donor deficiency: effects of a late maternal supplementation with folic acid. Int J Mol Sci 20:4","journal-title":"Int J Mol Sci"},{"key":"10099_CR8","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1093\/molehr\/gag040","volume":"9","author":"S Goldman","year":"2003","unstructured":"Goldman S, Weiss A, Eyali V, Shalev E (2003) Differential activity of the gelatinases (matrix metalloproteinases 2 and 9) in the fetal membranes and decidua, associated with labour. Mol Hum Reprod 9:367\u2013373","journal-title":"Mol Hum Reprod"},{"key":"10099_CR9","doi-asserted-by":"publisher","first-page":"S2","DOI":"10.1186\/1471-2393-10-S1-S2","volume":"10","author":"MG Gravett","year":"2010","unstructured":"Gravett MG, Rubens CE, Nunes TM (2010) Global report on preterm birth and stillbirth (2 of 7): discovery science. BMC Pregnancy Childbirth 10:S2","journal-title":"BMC Pregnancy Childbirth"},{"key":"10099_CR10","doi-asserted-by":"publisher","first-page":"1700043","DOI":"10.1002\/gch2.201700043","volume":"1","author":"M Imam","year":"2017","unstructured":"Imam M, Ismail M (2017) The impact of traditional food and lifestyle behavior on epigenetic burden of chronic disease. Glob Chall 1:1700043","journal-title":"Glob Chall"},{"key":"10099_CR11","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.psychres.2009.01.013","volume":"175","author":"A Kale","year":"2010","unstructured":"Kale A, Naphade N, Sapkale S et al (2010) Reduced folic acid, vitamin B12 and docosahexaenoic acid and increased homocysteine and cortisol in never- medicated schizophrenia patients: implications for altered one-carbon metabolism. Psychiatr Res 175:47\u201353","journal-title":"Psychiatr Res"},{"key":"10099_CR12","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1016\/j.gene.2017.11.054","volume":"5","author":"LMB Klassen","year":"2018","unstructured":"Klassen LMB, Chequin A, Manica GCM, Biembengut IV, Toledo MB, Baura VA, de O Pedrosa F, Ramos EAS, Costa FF, de Souza EM, Klassen G (2018) MMP9 gene expression regulation by intragenic epigenetic modifications in breast cancer. Gene 5:461\u2013466","journal-title":"Gene"},{"key":"10099_CR13","doi-asserted-by":"publisher","first-page":"5492","DOI":"10.1128\/MCB.18.9.5492","volume":"18","author":"S Kudo","year":"1998","unstructured":"Kudo S (1998) Methyl-CpG-binding protein MeCP2 represses Sp1 activated transcription of the human leukosialin gene when the promoter is methylated. Mol Cell Biol 18:5492\u20135499","journal-title":"Mol Cell Biol"},{"key":"10099_CR14","doi-asserted-by":"publisher","first-page":"e17706","DOI":"10.1371\/journal.pone.0017706","volume":"6","author":"A Kulkarni","year":"2011","unstructured":"Kulkarni A, Dangat K, Kale A, Sable P, Chavan-Gautam P, Joshi S (2011) Effects of altered maternal folic acid, vitamin b12 and docosahexaenoic acid on placental global dna methylation. PLoS ONE 6:e17706","journal-title":"PLoS ONE"},{"key":"10099_CR15","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/6082613","author":"M Lindschinger","year":"2019","unstructured":"Lindschinger M, Tatzber F, Schimetta W, Schmid I, Lindschinger B, Cvirn G, Stanger O, Lamont E, Wonisch W (2019) A randomized pilot trial to evaluate the bioavailability of natural versus synthetic vitamin b complexes in healthy humans and their effects on homocysteine, oxidative stress, and antioxidant levels. Oxid Med Cell Longev. https:\/\/doi.org\/10.1155\/2019\/6082613","journal-title":"Oxid Med Cell Longev"},{"key":"10099_CR16","doi-asserted-by":"publisher","first-page":"4108","DOI":"10.1038\/sj.onc.1202764","volume":"18","author":"DN Mancini","year":"1999","unstructured":"Mancini DN, Singh SM, Archer TK, Rodenhiser I (1999) Site- specific DNA methylation in the neurofibromatosis (NF1) promoter interferes with binding of CREB and SP1 transcription factors. Oncogene 18:4108\u20134119","journal-title":"Oncogene"},{"key":"10099_CR17","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1186\/s12864-015-1994-2","volume":"16","author":"M Moarii","year":"2015","unstructured":"Moarii M, Boeva V, Vert JP, Reyal F (2015) Changes in correlation between promoter methylation and gene expression in cancer. BMC Genom 16:873","journal-title":"BMC Genom"},{"key":"10099_CR18","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1016\/j.jnutbio.2012.03.003","volume":"23","author":"S Olivia","year":"2012","unstructured":"Olivia S, Karilyn E, Dana C (2012) Nutrition and epigenetics: an interplay of dietary methyl donors one-carbon metabolism, and DNA methylation. J Nutr Biochem 23:853\u2013859","journal-title":"J Nutr Biochem"},{"key":"10099_CR19","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/j.ajog.2006.03.109","volume":"196","author":"CE Pennell","year":"2007","unstructured":"Pennell CE, Jacobsson B, Williams SM, Buus RM, Muglia LJ et al (2007) Genetic epidemiologic studies of preterm birth: guidelines for research. Am J Obstet Gynecol 196:107\u2013118","journal-title":"Am J Obstet Gynecol"},{"key":"10099_CR20","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/j.yexmp.2009.08.001","volume":"87","author":"M Shokry","year":"2009","unstructured":"Shokry M, Omran OM, Hassan HI, Elsedfy GO, Hussein M (2009) Expression of matrix metalloproteinases 2 and 9 in human trophoblasts of normal and preeclamptic placentas: preliminary findings. Exp Mol Pathol 87:219\u2013225","journal-title":"Exp Mol Pathol"},{"key":"10099_CR21","doi-asserted-by":"publisher","first-page":"878","DOI":"10.1016\/j.mehy.2011.08.001","volume":"77","author":"D Sundrani","year":"2011","unstructured":"Sundrani D, Chavan Gautam P, Mehendale S, Joshi S (2011) Altered metabolism of maternal micronutrients and omega 3 fatty acids epigenetically regulate matrix metalloproteinases in preterm pregnancy: a novel hypothesis. Med Hypotheses 77:878\u2013883","journal-title":"Med Hypotheses"},{"key":"10099_CR22","doi-asserted-by":"publisher","first-page":"e29855","DOI":"10.1371\/journal.pone.0029855","volume":"7","author":"D Sundrani","year":"2012","unstructured":"Sundrani D, Chavan-Gautam P, Pisal H, Mehendale S, Joshi S (2012) Matrix metalloproteinase-1 and -9 in human placenta during spontaneous vaginal delivery and caesarean sectioning in preterm pregnancy. PLoS ONE 7:e29855","journal-title":"PLoS ONE"},{"key":"10099_CR23","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1530\/REP-12-0520","volume":"145","author":"D Sundrani","year":"2013","unstructured":"Sundrani D, Chavan-Gautam P, Pisal H, Mehendale S, Joshi S (2013) Matrix metalloproteinases-2, -3 and tissue inhibitors of metalloproteinases-1, -2 in placentas from preterm pregnancies and their association with one-carbon metabolites. Reproduction 145:401\u2013410","journal-title":"Reproduction"},{"key":"10099_CR24","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1002\/iub.1687","volume":"69","author":"D Sundrani","year":"2017","unstructured":"Sundrani D, Narange A, Mehendale S, Joshi S, Chavan-Gautam P (2017) Investigating the expression of MMPs and TIMPs in preterm placenta and role of CpG methylation in regulating MMP-9 expression. IUBMB Life 69:985\u2013993","journal-title":"IUBMB Life"},{"key":"10099_CR25","first-page":"3887","volume":"24","author":"AM Szpaderska","year":"2004","unstructured":"Szpaderska AM, Silberman S, Ahmed Y, Frankfater A (2004) Sp1 regulates cathepsin B transcription and invasiveness in murine B16 melanoma cells. Anticancer Res 24:3887\u20133891","journal-title":"Anticancer Res"},{"key":"10099_CR26","doi-asserted-by":"publisher","first-page":"649","DOI":"10.2741\/2089","volume":"12","author":"A Weiss","year":"2007","unstructured":"Weiss A, Goldman S, Shalev E (2007) The matrix metalloproteinases (MMPS) in the decidua and fetal membranes. Front Biosci 12:649\u2013659","journal-title":"Front Biosci"},{"key":"10099_CR27","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1152\/physiol.00029.2013","volume":"28","author":"A Yabluchanskiy","year":"2013","unstructured":"Yabluchanskiy A, Ma Y, Padmanabhan Iyer R, Hall ME, Lindsey ML (2013) Matrix metalloproteinase-9: many shades of function in cardiovascular disease. Physiology 28:391\u2013403","journal-title":"Physiology"}],"container-title":["Biochemical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10528-021-10099-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10528-021-10099-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10528-021-10099-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,25]],"date-time":"2022-01-25T22:09:05Z","timestamp":1643148545000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10528-021-10099-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,5]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["10099"],"URL":"https:\/\/doi.org\/10.1007\/s10528-021-10099-y","relation":{},"ISSN":["0006-2928","1573-4927"],"issn-type":[{"type":"print","value":"0006-2928"},{"type":"electronic","value":"1573-4927"}],"subject":[],"published":{"date-parts":[[2021,7,5]]},"assertion":[{"value":"3 March 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 June 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 July 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that there is no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}