{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,12]],"date-time":"2025-07-12T01:22:49Z","timestamp":1752283369030,"version":"3.37.3"},"reference-count":79,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T00:00:00Z","timestamp":1691625600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T00:00:00Z","timestamp":1691625600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001412","name":"Council of Scientific and Industrial Research, India","doi-asserted-by":"publisher","award":["09\/254(0300)\/2019-EMR-I"],"award-info":[{"award-number":["09\/254(0300)\/2019-EMR-I"]}],"id":[{"id":"10.13039\/501100001412","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Biochem Genet"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1007\/s10528-023-10469-8","type":"journal-article","created":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T17:01:59Z","timestamp":1691686919000},"page":"1216-1230","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["RAD51 and Infertility: A Review and Case-Control Study"],"prefix":"10.1007","volume":"62","author":[{"given":"Jatinder Singh","family":"Sahota","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ranveer Singh","family":"Thakur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kamlesh","family":"Guleria","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6648-1906","authenticated-orcid":false,"given":"Vasudha","family":"Sambyal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,8,10]]},"reference":[{"issue":"1","key":"10469_CR1","doi-asserted-by":"publisher","first-page":"3961","DOI":"10.1038\/s41467-018-06384-x","volume":"9","author":"CM Abreu","year":"2018","unstructured":"Abreu CM, Prakash R, Romanienko PJ, Roig I, Keeney S, Jasin M (2018) Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination. Nat Commun 9(1):3961. https:\/\/doi.org\/10.1038\/s41467-018-06384-x","journal-title":"Nat Commun"},{"issue":"2","key":"10469_CR2","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1093\/clinchem\/36.2.261","volume":"36","author":"K Adeli","year":"1990","unstructured":"Adeli K, Ogbonna G (1990) Rapid purification of human DNA from whole blood for potential application in clinical chemistry laboratories. Clin Chem 36(2):261\u2013264. https:\/\/doi.org\/10.1093\/clinchem\/36.2.261","journal-title":"Clin Chem"},{"issue":"1","key":"10469_CR3","doi-asserted-by":"publisher","first-page":"8829","DOI":"10.1038\/ncomms9829","volume":"6","author":"N Ameziane","year":"2015","unstructured":"Ameziane N, May P, Haitjema A, Van De Vrugt HJ, van Rossum-Fikkert SE, Ristic D, Williams GJ, Balk J, Rockx D, Li H, Rooimans MA (2015) A novel fanconi anaemia subtype associated with a dominant-negative mutation in RAD51. Nat Commun 6(1):8829. https:\/\/doi.org\/10.1038\/ncomms9829","journal-title":"Nat Commun"},{"issue":"7","key":"10469_CR4","doi-asserted-by":"publisher","first-page":"1705","DOI":"10.1093\/humrep\/del065","volume":"21","author":"S Assou","year":"2006","unstructured":"Assou S, Anahory T, Pantesco V, Le Carrour T, Pellestor F, Klein B, Reyftmann L, Dechaud H, De Vos J, Hamamah S (2006) The human cumulus\u2013oocyte complex gene-expression profile. Hum Reprod 21(7):1705\u20131719. https:\/\/doi.org\/10.1093\/humrep\/del065","journal-title":"Hum Reprod"},{"issue":"Suppl 2","key":"10469_CR5","doi-asserted-by":"publisher","first-page":"S273","DOI":"10.4103\/jcrt.JCRT_902_20","volume":"18","author":"JS Bali","year":"2022","unstructured":"Bali JS, Sambyal V, Guleria K, Mehrotra S, Singh NR, Uppal MS, Manjari M, Sudan M (2022) RAD51 135G > C polymorphism in esophageal cancer and meta-analysis in gastrointestinal tract cancers. J Cancer Res Ther 18(Suppl 2):S273\u2013S279. https:\/\/doi.org\/10.4103\/jcrt.JCRT_902_20","journal-title":"J Cancer Res Ther"},{"issue":"5","key":"10469_CR6","doi-asserted-by":"publisher","first-page":"e105","DOI":"10.1371\/journal.pbio.0050105","volume":"5","author":"LA Bannister","year":"2007","unstructured":"Bannister LA, Pezza RJ, Donaldson JR, de Rooij DG, Schimenti KJ, Camerini-Otero RD, Schimenti JC (2007) A dominant, recombination-defective allele of Dmc1 causing male-specific sterility. PLoS Biol 5(5):e105. https:\/\/doi.org\/10.1371\/journal.pbio.0050105","journal-title":"PLoS Biol"},{"key":"10469_CR7","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1146\/annurev-genet-021920-092410","volume":"54","author":"B Bonilla","year":"2020","unstructured":"Bonilla B, Hengel SR, Grundy MK, Bernstein KA (2020) RAD51 gene family structure and function. Annu Rev Genet 54:25\u201346. https:\/\/doi.org\/10.1146\/annurev-genet-021920-092410","journal-title":"Annu Rev Genet"},{"issue":"8","key":"10469_CR8","doi-asserted-by":"publisher","first-page":"1433","DOI":"10.1128\/MCB.01328-14","volume":"35","author":"JM Bryant","year":"2015","unstructured":"Bryant JM, Donahue G, Wang X, Meyer-Ficca M, Luense LJ, Weller AH, Bartolomei MS, Blobel GA, Meyer RG, Garcia BA, Berger SL (2015) Characterization of BRD4 during mammalian postmeiotic sperm development. Mol Cell Biol 35(8):1433\u20131448. https:\/\/doi.org\/10.1128\/MCB.01328-14","journal-title":"Mol Cell Biol"},{"issue":"9","key":"10469_CR9","doi-asserted-by":"publisher","first-page":"gaab058","DOI":"10.1093\/molehr\/gaab058","volume":"27","author":"D Cao","year":"2021","unstructured":"Cao D, Shi F, Guo C, Liu Y, Lin Z, Zhang J, Li RHW, Yao Y, Liu K, Ng EHY, Yeung WSB (2021) A pathogenic DMC1 frameshift mutation causes nonobstructive azoospermia but not primary ovarian insufficiency in humans. Mol Hum Reprod 27(9):gaab058. https:\/\/doi.org\/10.1093\/molehr\/gaab058","journal-title":"Mol Hum Reprod"},{"key":"10469_CR10","doi-asserted-by":"publisher","first-page":"S132","DOI":"10.1074\/mcp.RA118.001278","volume":"18","author":"J Castillo","year":"2019","unstructured":"Castillo J, Knol JC, Korver CM, Piersma SR, Pham TV, de Goeij-de Haas RR, van Pelt AM, Jimenez CR, Jansen BJ (2019) Human testis phosphoproteome reveals kinases as potential targets in spermatogenesis and testicular cancer. Mol Cell Proteomics 18:S132\u2013S144. https:\/\/doi.org\/10.1074\/mcp.RA118.001278","journal-title":"Mol Cell Proteomics"},{"issue":"16","key":"10469_CR11","doi-asserted-by":"publisher","first-page":"8859","DOI":"10.1073\/pnas.2001165117","volume":"117","author":"I Ceppi","year":"2020","unstructured":"Ceppi I, Howard SM, Kasaciunaite K, Pinto C, Anand R, Seidel R, Cejka P (2020) CtIP promotes the motor activity of DNA2 to accelerate long-range DNA end resection. Proc Natl Acad Sci USA 117(16):8859\u20138869. https:\/\/doi.org\/10.1073\/pnas.2001165117","journal-title":"Proc Natl Acad Sci USA"},{"issue":"9","key":"10469_CR12","doi-asserted-by":"publisher","first-page":"e858","DOI":"10.1371\/journal.pone.0000858","volume":"2","author":"LT Chen","year":"2007","unstructured":"Chen LT, Ko TP, Chang YW, Lin KA, Wang AHJ, Wang TF (2007) Structural and functional analyses of five conserved positively charged residues in the L1 and N-terminal DNA binding motifs of archaeal RADA protein. PLoS ONE 2(9):e858. https:\/\/doi.org\/10.1371\/journal.pone.0000858","journal-title":"PLoS ONE"},{"issue":"2","key":"10469_CR13","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1007\/s13238-021-00844-9","volume":"13","author":"B Chen","year":"2022","unstructured":"Chen B, Guo J, Wang T, Lee Q, Ming J, Ding F, Li H, Zhang Z, Li L, Cao Y, Na J (2022) Maternal heterozygous mutation in CHEK1 leads to mitotic arrest in human zygotes. Protein Cell 13(2):148\u2013154. https:\/\/doi.org\/10.1007\/s13238-021-00844-9","journal-title":"Protein Cell"},{"issue":"6","key":"10469_CR14","doi-asserted-by":"publisher","first-page":"1383","DOI":"10.1016\/j.celrep.2017.01.024","volume":"18","author":"J Dai","year":"2017","unstructured":"Dai J, Voloshin O, Potapova S, Camerini-Otero RD (2017) Meiotic knockdown and complementation reveals essential role of RAD51 in mouse spermatogenesis. Cell Rep 18(6):1383\u20131394. https:\/\/doi.org\/10.1016\/j.celrep.2017.01.024","journal-title":"Cell Rep"},{"issue":"2","key":"10469_CR15","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1080\/15384101.2015.1121350","volume":"15","author":"PS Danielian","year":"2016","unstructured":"Danielian PS, Hess RA, Lees JA (2016) E2f4 and E2f5 are essential for the development of the male reproductive system. Cell Cycle 15(2):250\u2013260. https:\/\/doi.org\/10.1080\/15384101.2015.1121350","journal-title":"Cell Cycle"},{"issue":"3","key":"10469_CR16","doi-asserted-by":"publisher","first-page":"741","DOI":"10.3390\/genes14030741","volume":"14","author":"AP Das","year":"2023","unstructured":"Das AP, Chaudhary N, Tyagi S, Agarwal SM (2023) Meta-analysis of 49 SNPs Covering 25,446 cases and 41,106 controls identifies polymorphisms in hormone regulation and DNA repair genes Associated with increased endometrial Cancer risk. Genes 14(3):741. https:\/\/doi.org\/10.3390\/genes14030741","journal-title":"Genes"},{"issue":"3","key":"10469_CR17","doi-asserted-by":"publisher","first-page":"100049","DOI":"10.1016\/j.modpat.2022.100049","volume":"36","author":"KD Doig","year":"2023","unstructured":"Doig KD, Fellowes AP, Fox SB (2023) Homologous recombination Repair Deficiency: an overview for pathologists. Mod Pathol 36(3):100049. https:\/\/doi.org\/10.1016\/j.modpat.2022.100049","journal-title":"Mod Pathol"},{"issue":"11","key":"10469_CR18","doi-asserted-by":"publisher","first-page":"2300188","DOI":"10.1002\/advs.202300188","volume":"10","author":"S Du","year":"2023","unstructured":"Du S, Li W, Zhang Y, Xue Y, Hou X, Yan J, Cheng J, Deng B, McComb DW, Lin J, Zeng H (2023) Cholesterol-amino\u2010phosphate (CAP) derived lipid nanoparticles for delivery of Self\u2010Amplifying RNA and restoration of Spermatogenesis in Infertile mice. Adv Sci 10(11):2300188. https:\/\/doi.org\/10.1002\/advs.202300188","journal-title":"Adv Sci"},{"issue":"14","key":"10469_CR19","doi-asserted-by":"publisher","first-page":"1780","DOI":"10.1038\/onc.2014.121","volume":"34","author":"S El Ghamrasni","year":"2015","unstructured":"El Ghamrasni S, Cardoso R, Halaby MJ, Zeegers D, Harding S, Kumareswaran R, Yavorska T, Chami N, Jurisicova A, Sanchez O, Hande MP (2015) Cooperation of Blm and Mus81 in development, fertility, genomic integrity and cancer suppression. Oncogene 34(14):1780\u20131789. https:\/\/doi.org\/10.1038\/onc.2014.121","journal-title":"Oncogene"},{"issue":"12","key":"10469_CR20","doi-asserted-by":"publisher","first-page":"2347","DOI":"10.1038\/s41418-022-01021-z","volume":"29","author":"MM Franca","year":"2022","unstructured":"Franca MM, Condezo YB, Elzaiat M, Felipe-Medina N, S\u00e1nchez-S\u00e1ez F, Mu\u00f1oz S, Sainz-Urruela R, Mart\u00edn-Herv\u00e1s MR, Garc\u00eda-Valiente R, S\u00e1nchez-Mart\u00edn MA, Astudillo A (2022) A truncating variant of RAD51B associated with primary ovarian insufficiency provides insights into its meiotic and somatic functions. Cell Death Differ 29(12):2347\u20132361. https:\/\/doi.org\/10.1038\/s41418-022-01021-z","journal-title":"Cell Death Differ"},{"key":"10469_CR21","doi-asserted-by":"publisher","first-page":"765","DOI":"10.3389\/fphys.2019.00765","volume":"10","author":"H Gao","year":"2019","unstructured":"Gao H, Wen H, Cao C, Dong D, Yang C, Xie S, Zhang J, Huang X, Huang X, Yuan S, Dong W (2019) Overexpression of microRNA-10a in germ cells causes male infertility by targeting Rad51 in mouse and human. Front Physiol 10:765. https:\/\/doi.org\/10.3389\/fphys.2019.00765","journal-title":"Front Physiol"},{"issue":"2","key":"10469_CR22","doi-asserted-by":"publisher","first-page":"44","DOI":"10.5005\/jp-journals-10016-1218","volume":"12","author":"R Govindhasamy","year":"2021","unstructured":"Govindhasamy R, Govindhasamy P, Vanga R, Burute P (2021) Role of TP53 gene polymorphism in male infertility. Int J Infertil Fetal Med 12(2):44\u201348. https:\/\/doi.org\/10.5005\/jp-journals-10016-1218","journal-title":"Int J Infertil Fetal Med"},{"issue":"3","key":"10469_CR23","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1136\/jmedgenet-2017-104992","volume":"55","author":"WB He","year":"2018","unstructured":"He WB, Tu CF, Liu Q, Meng LL, Yuan SM, Luo AX, He FS, Shen J, Li W, Du J, Zhong CG (2018) DMC1 mutation that causes human non-obstructive azoospermia and premature ovarian insufficiency identified by whole-exome sequencing. J Med Genet 55(3):198\u2013204. https:\/\/doi.org\/10.1136\/jmedgenet-2017-104992","journal-title":"J Med Genet"},{"issue":"12","key":"10469_CR24","doi-asserted-by":"publisher","first-page":"4181","DOI":"10.1093\/nar\/gkn362","volume":"36","author":"J Hikiba","year":"2008","unstructured":"Hikiba J, Hirota K, Kagawa W, Ikawa S, Kinebuchi T, Sakane I, Takizawa Y, Yokoyama S, Mandon-Pepin B, Nicolas A, Shibata T (2008) Structural and functional analyses of the DMC1-M200V polymorphism found in the human population. Nucleic Acids Res 36(12):4181\u20134190. https:\/\/doi.org\/10.1093\/nar\/gkn362","journal-title":"Nucleic Acids Res"},{"key":"10469_CR25","doi-asserted-by":"publisher","first-page":"116917","DOI":"10.1016\/j.envpol.2021.116917","volume":"279","author":"Y Hong","year":"2021","unstructured":"Hong Y, Mu X, Ji X, Chen X, Geng Y, Zhang Y, Liu Q, Li F, Wang Y, He J (2021) In-utero exposure to HT-2 toxin affects meiotic progression and early oogenesis in foetal oocytes by increasing oxidative stress. Environ Pollut 279:116917. https:\/\/doi.org\/10.1016\/j.envpol.2021.116917","journal-title":"Environ Pollut"},{"issue":"1","key":"10469_CR26","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1002\/cam4.4891","volume":"12","author":"J Hu","year":"2023","unstructured":"Hu J, Xu Z, Ye Z, Li J, Hao Z, Wang Y (2023) The association between single nucleotide polymorphisms and ovarian cancer risk: a systematic review and network meta-analysis. Cancer Med 12(1):541\u2013556. https:\/\/doi.org\/10.1002\/cam4.4891","journal-title":"Cancer Med"},{"key":"10469_CR27","doi-asserted-by":"publisher","unstructured":"Ivy SC, Shabnaz S, Shahriar M, Jafrin S, Aka TD, Aziz MA, Islam MS (2021) Association of RAD51 and XRCC2 Gene Polymorphisms with Cervical Cancer Risk in the Bangladeshi Women. Asian Pac J Cancer Prev 22(7): 2099. https:\/\/doi.org\/10.31557\/APJCP.2021.22.7.2099","DOI":"10.31557\/APJCP.2021.22.7.2099"},{"issue":"1","key":"10469_CR28","doi-asserted-by":"publisher","first-page":"dev191189","DOI":"10.1242\/dev.191189","volume":"148","author":"CJ Jorgez","year":"2021","unstructured":"Jorgez CJ, Seth A, Wilken N, Bournat JC, Chen CH, Lamb DJ (2021) E2F1 regulates testicular descent and controls spermatogenesis by influencing WNT4 signaling. Development 148(1):dev191189. https:\/\/doi.org\/10.1242\/dev.191189","journal-title":"Development"},{"issue":"3","key":"10469_CR29","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1007\/s100380050199","volume":"45","author":"M Kato","year":"2000","unstructured":"Kato M, Yano KI, Matsuo F, Saito H, Katagiri T, Kurumizaka H, Yoshimoto M, Kasumi F, Akiyama F, Sakamoto G, Nagawa H (2000) Identification of Rad51 alteration in patients with bilateral breast cancer. J Hum Genet 45(3):133\u2013137. https:\/\/doi.org\/10.1007\/s100380050199","journal-title":"J Hum Genet"},{"issue":"1","key":"10469_CR30","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/srep34110","volume":"6","author":"KH Kim","year":"2016","unstructured":"Kim KH, Park JH, Kim EY, Ko JJ, Park KS, Lee KA (2016) The role of Rad51 in safeguarding mitochondrial activity during the meiotic cell cycle in mammalian oocytes. Sci Rep 6(1):1\u201312. https:\/\/doi.org\/10.1038\/srep34110","journal-title":"Sci Rep"},{"issue":"3","key":"10469_CR31","doi-asserted-by":"publisher","first-page":"1184","DOI":"10.1096\/fj.201700854RR","volume":"32","author":"HR Kim","year":"2018","unstructured":"Kim HR, Kim YS, Yoon JA, Yang SC, Park M, Seol DW, Lyu SW, Jun JH, Lim HJ, Lee DR, Song H (2018) Estrogen induces EGR1 to fine-tune its actions on uterine epithelium by controlling PR signaling for successful embryo implantation. FASEB J 32(3):1184\u20131195. https:\/\/doi.org\/10.1096\/fj.201700854RR","journal-title":"FASEB J"},{"issue":"8","key":"10469_CR32","doi-asserted-by":"publisher","first-page":"3013","DOI":"10.1172\/JCI92069","volume":"127","author":"K Knies","year":"2017","unstructured":"Knies K, Inano S, Ram\u00edrez MJ, Ishiai M, Surrall\u00e9s J, Takata M, Schindler D (2017) Biallelic mutations in the ubiquitin ligase RFWD3 cause fanconi anemia. J Clin Invest 127(8):3013\u20133027. https:\/\/doi.org\/10.1172\/JCI92069","journal-title":"J Clin Invest"},{"key":"10469_CR33","doi-asserted-by":"publisher","first-page":"748","DOI":"10.3389\/fmolb.2022.934042","volume":"9","author":"M Kohzaki","year":"2022","unstructured":"Kohzaki M (2022) Mammalian resilience revealed by a comparison of human diseases and mouse models associated with DNA helicase deficiencies. Front Mol Biosci 9:748. https:\/\/doi.org\/10.3389\/fmolb.2022.934042","journal-title":"Front Mol Biosci"},{"issue":"2","key":"10469_CR34","first-page":"2181","volume":"10","author":"T Korak","year":"2017","unstructured":"Korak T, Ergul E, Uren N, Altinok D, Simsek T, Utkan NZ, Zafer N, Gulluoglu CB, Sazci A (2017) RAD51 (rs1801320) gene polymorphism and breast cancer risk in turkish population. Int J Clin Exp Pathol 10(2):2181\u20132186","journal-title":"Int J Clin Exp Pathol"},{"issue":"5","key":"10469_CR35","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1083\/jcb.200608130","volume":"176","author":"S Kuznetsov","year":"2007","unstructured":"Kuznetsov S, Pellegrini M, Shuda K, Fernandez-Capetillo O, Liu Y, Martin BK, Burkett S, Southon E, Pati D, Tessarollo L, West SC (2007) RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females. J Cell Biol 176(5):581\u2013592. https:\/\/doi.org\/10.1083\/jcb.200608130","journal-title":"J Cell Biol"},{"issue":"21","key":"10469_CR36","doi-asserted-by":"publisher","first-page":"11257","DOI":"10.1073\/pnas.1920368117","volume":"117","author":"WH Lan","year":"2020","unstructured":"Lan WH, Lin SY, Kao CY, Chang WH, Yeh HY, Chang HY, Chi P, Li HW (2020) Rad51 facilitates filament assembly of meiosis-specific Dmc1 recombinase. Proc Natl Acad Sci USA 117(21):11257\u201311264. https:\/\/doi.org\/10.1073\/pnas.1920368117","journal-title":"Proc Natl Acad Sci USA"},{"issue":"1","key":"10469_CR37","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1016\/j.devcel.2007.10.017","volume":"14","author":"J Li","year":"2008","unstructured":"Li J, Ran C, Li E, Gordon F, Comstock G, Siddiqui H, Cleghorn W, Chen HZ, Kornacker K, Liu CG, Pandit SK (2008) Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development. Dev Cell 14(1):62\u201375. https:\/\/doi.org\/10.1016\/j.devcel.2007.10.017","journal-title":"Dev Cell"},{"issue":"5","key":"10469_CR38","doi-asserted-by":"publisher","first-page":"1331","DOI":"10.1093\/biolre\/ioac162","volume":"107","author":"P Li","year":"2022","unstructured":"Li P, Tang J, Yu Z, Jin C, Wang Z, Li M, Zou D, Mang X, Liu J, Lu Y, Miao S (2022) CHD4 acts as a critical regulator in the survival of spermatogonial stem cells in mice. Biol Reprod 107(5):1331\u20131344. https:\/\/doi.org\/10.1093\/biolre\/ioac162","journal-title":"Biol Reprod"},{"issue":"1","key":"10469_CR39","doi-asserted-by":"publisher","first-page":"e12726","DOI":"10.1111\/cpr.12726","volume":"53","author":"QX Liang","year":"2020","unstructured":"Liang QX, Wang ZB, Lei WL, Lin F, Qiao JY, Filhol-Cochet O, Boldyreff B, Schatten H, Sun QY, Qian WP (2020) Deletion of Ck2\u03b2 gene causes germ cell development arrest and azoospermia in male mice. Cell Prolif 53(1):e12726. https:\/\/doi.org\/10.1111\/cpr.12726","journal-title":"Cell Prolif"},{"key":"10469_CR40","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1146\/annurev.biochem.052308.093131","volume":"79","author":"MR Lieber","year":"2010","unstructured":"Lieber MR (2010) The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. Annu Rev Biochem 79:181\u2013211. https:\/\/doi.org\/10.1146\/annurev.biochem.052308.093131","journal-title":"Annu Rev Biochem"},{"issue":"12","key":"10469_CR41","doi-asserted-by":"publisher","first-page":"1206","DOI":"10.1091\/mbc.E19-12-0701","volume":"31","author":"TM Little","year":"2020","unstructured":"Little TM, Jordan PW (2020) PLK1 is required for chromosome compaction and microtubule organization in mouse oocytes. Mol Biol Cell 31(12):1206\u20131217. https:\/\/doi.org\/10.1091\/mbc.E19-12-0701","journal-title":"Mol Biol Cell"},{"issue":"13","key":"10469_CR42","doi-asserted-by":"publisher","first-page":"3421","DOI":"10.1093\/hmg\/ddu051","volume":"23","author":"E Llano","year":"2014","unstructured":"Llano E, Gomez- HL, Garc\u00eda-Tu\u00f1\u00f3n I, S\u00e1nchez-Mart\u00edn M, Caburet S, Barbero JL, Schimenti JC, Veitia RA, Pendas AM (2014) STAG3 is a strong candidate gene for male infertility. Hum Mol Genet 23(13):3421\u20133431. https:\/\/doi.org\/10.1093\/hmg\/ddu051","journal-title":"Hum Mol Genet"},{"issue":"10","key":"10469_CR43","doi-asserted-by":"publisher","first-page":"e3566","DOI":"10.1210\/clinem\/dgaa505","volume":"105","author":"W Luo","year":"2020","unstructured":"Luo W, Guo T, Li G, Liu R, Zhao S, Song M, Zhang L, Wang S, Chen ZJ, Qin Y (2020) Variants in homologous recombination genes EXO1 and RAD51 related with premature ovarian insufficiency. J Clin Endocrinol Metab 105(10):e3566\u2013e3574. https:\/\/doi.org\/10.1210\/clinem\/dgaa505","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"10469_CR44","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1038\/s41467-020-20258-1","volume":"12","author":"SC Luo","year":"2021","unstructured":"Luo SC, Yeh HY, Lan WH, Wu YM, Yang CH, Chang HY, Su GC, Lee CY, Wu WJ, Li HW, Ho MC (2021) Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures. Nat Commun 12(1):115. https:\/\/doi.org\/10.1038\/s41467-020-20258-1","journal-title":"Nat Commun"},{"key":"10469_CR45","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.ejogrb.2017.09.011","volume":"218","author":"MQ Lv","year":"2017","unstructured":"Lv MQ, Wang J, Yu XQ, Hong HH, Ren WJ, Ge P, Zhou DX (2017) Association between X-ray repair cross-complementing group 1 (XRCC1) Arg399Gln polymorphism and endometriosis: a systematic review and meta-analysis. Eur J Obstet Gynecol Reprod Biol 218:12\u201320. https:\/\/doi.org\/10.1016\/j.ejogrb.2017.09.011","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"2","key":"10469_CR46","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1093\/nar\/gkw1125","volume":"45","author":"CJ Ma","year":"2017","unstructured":"Ma CJ, Gibb B, Kwon Y, Sung P, Greene EC (2017) Protein dynamics of human RPA and RAD51 on ssDNA during assembly and disassembly of the RAD51 filament. Nucleic Acids Res 45(2):749\u2013761. https:\/\/doi.org\/10.1093\/nar\/gkw1125","journal-title":"Nucleic Acids Res"},{"issue":"10","key":"10469_CR47","doi-asserted-by":"publisher","first-page":"817","DOI":"10.1016\/s1297-9589(02)00444-7","volume":"30","author":"B Mandon-Pepin","year":"2002","unstructured":"Mandon-Pepin B, Derbois C, Matsuda F, Cotinot C, Wolgemuth DJ, Smith K, McElreavey K, Nicolas A, Fellous M (2002) Human infertility: meiotic genes as potential candidates. Gynecol Obstet Fertil 30(10):817\u2013821. https:\/\/doi.org\/10.1016\/s1297-9589(02)00444-7","journal-title":"Gynecol Obstet Fertil"},{"issue":"1","key":"10469_CR48","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1530\/EJE-07-0400","volume":"158","author":"B Mandon-P\u00e9pin","year":"2008","unstructured":"Mandon-P\u00e9pin B, Touraine P, Kuttenn F, Derbois C, Rouxel A, Matsuda F, Nicolas A, Cotinot C, Fellous M (2008) Genetic investigation of four meiotic genes in women with premature ovarian failure. Eur J Endocrinol 158(1):107\u2013115. https:\/\/doi.org\/10.1530\/EJE-07-0400","journal-title":"Eur J Endocrinol"},{"issue":"1","key":"10469_CR49","doi-asserted-by":"publisher","first-page":"1407","DOI":"10.1038\/s41467-019-09190-1","volume":"10","author":"K Matsuzaki","year":"2019","unstructured":"Matsuzaki K, Kondo S, Ishikawa T, Shinohara A (2019) Human RAD51 paralogue SWSAP1 fosters RAD51 filament by regulating the anti-recombinase FIGNL1 AAA + ATPase. Nat Commun 10(1):1407. https:\/\/doi.org\/10.1038\/s41467-019-09190-1","journal-title":"Nat Commun"},{"issue":"22","key":"10469_CR50","doi-asserted-by":"publisher","first-page":"1999","DOI":"10.1212\/WNL.0000000000000477","volume":"82","author":"A M\u00e9neret","year":"2014","unstructured":"M\u00e9neret A, Depienne C, Riant F, Trouillard O, Bouteiller D, Cincotta M, Bitoun P, Wickert J, Lagroua I, Westenberger A, Borgheresi A (2014) Congenital mirror movements: mutational analysis of RAD51 and DCC in 26 cases. Neurology 82(22):1999\u20132002. https:\/\/doi.org\/10.1212\/WNL.0000000000000477","journal-title":"Neurology"},{"issue":"2","key":"10469_CR51","doi-asserted-by":"publisher","first-page":"e13925","DOI":"10.1111\/and.13925","volume":"53","author":"A Metin Mahmutoglu","year":"2021","unstructured":"Metin Mahmutoglu A, Gunes S, Asci R, Henkel R, Aydin O (2021) Association of XRCC1 and ERCC2 promoters\u2019 methylation with chromatin condensation and sperm DNA fragmentation in idiopathic oligoasthenoteratozoospermic men. Andrologia 53(2):e13925. https:\/\/doi.org\/10.1111\/and.13925","journal-title":"Andrologia"},{"issue":"4","key":"10469_CR52","doi-asserted-by":"publisher","first-page":"1592","DOI":"10.1002\/jcp.22876","volume":"227","author":"NR Mtango","year":"2012","unstructured":"Mtango NR, Sutovsky M, Susor A, Zhong Z, Latham KE, Sutovsky P (2012) Essential role of maternal UCHL1 and UCHL3 in fertilization and preimplantation embryo development. J Cell Physiol 227(4):1592\u20131603. https:\/\/doi.org\/10.1002\/jcp.22876","journal-title":"J Cell Physiol"},{"key":"10469_CR53","doi-asserted-by":"publisher","first-page":"669732","DOI":"10.3389\/fcell.2021.669732","volume":"9","author":"X Mu","year":"2021","unstructured":"Mu X, Tu Z, Chen X, Hong Y, Geng Y, Zhang Y, Ji X, Liu T, Wang Y, He J (2021) In utero exposure to excessive estrogen impairs homologous recombination and oogenesis via estrogen receptor 2 in mice. Front Cell Dev Biol 9:669732. https:\/\/doi.org\/10.3389\/fcell.2021.669732","journal-title":"Front Cell Dev Biol"},{"issue":"2","key":"10469_CR54","doi-asserted-by":"publisher","first-page":"74","DOI":"10.3390\/reprodmed4020009","volume":"4","author":"I Munshi","year":"2023","unstructured":"Munshi I, Sachdeva G (2023) Genomic insults and their redressal in the Eutopic Endometrium of Women with Endometriosis. Reprod Med 4(2):74\u201388. https:\/\/doi.org\/10.3390\/reprodmed4020009","journal-title":"Reprod Med"},{"issue":"12","key":"10469_CR55","doi-asserted-by":"publisher","first-page":"2930","DOI":"10.3390\/cancers13122930","volume":"13","author":"E Orhan","year":"2021","unstructured":"Orhan E, Velazquez C, Tabet I, Sardet C, Theillet C (2021) Regulation of RAD51 at the transcriptional and functional levels: what prospects for cancer therapy? Cancers 13(12):2930. https:\/\/doi.org\/10.3390\/cancers13122930","journal-title":"Cancers"},{"key":"10469_CR56","doi-asserted-by":"publisher","first-page":"3267","DOI":"10.1007\/s10815-021-02324-9","volume":"38","author":"AR Palomares","year":"2021","unstructured":"Palomares AR, Castillo-Dom\u00ednguez AA, Ruiz-Gald\u00f3n M, Rodriguez-Wallberg KA, Reyes-Engel A (2021) Genetic variants in the p53 pathway influence implantation and pregnancy maintenance in IVF treatments using donor oocytes. J Assist Reprod Genet 38:3267\u20133275. https:\/\/doi.org\/10.1007\/s10815-021-02324-9","journal-title":"J Assist Reprod Genet"},{"issue":"5","key":"10469_CR57","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1016\/S1097-2765(00)80069-6","volume":"1","author":"DL Pittman","year":"1998","unstructured":"Pittman DL, Cobb J, Schimenti KJ, Wilson LA, Cooper DM, Brignull E, Handel MA, Schimenti JC (1998) Meiotic prophase arrest with failure of chromosome synapsis in mice deficient for Dmc1, a germline-specific RecA homolog. Mol Cell 1(5):697\u2013705. https:\/\/doi.org\/10.1016\/S1097-2765(00)80069-6","journal-title":"Mol Cell"},{"issue":"7","key":"10469_CR58","doi-asserted-by":"publisher","first-page":"628","DOI":"10.3390\/life11070628","volume":"11","author":"A Puzuka","year":"2021","unstructured":"Puzuka A, Alksere B, Gailite L, Erenpreiss J (2021) Idiopathic infertility as a feature of genome instability. Life 11(7):628. https:\/\/doi.org\/10.3390\/life11070628","journal-title":"Life"},{"issue":"1","key":"10469_CR59","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1038\/s41420-022-00921-w","volume":"8","author":"J Qin","year":"2022","unstructured":"Qin J, Huang T, Wang J, Xu L, Dang Q, Xu X, Liu H, Liu Z, Shao C, Zhang X (2022) RAD51 is essential for spermatogenesis and male fertility in mice. Cell Death Discov 8(1):118. https:\/\/doi.org\/10.1038\/s41420-022-00921-w","journal-title":"Cell Death Discov"},{"issue":"5","key":"10469_CR60","doi-asserted-by":"publisher","first-page":"1194","DOI":"10.1093\/humrep\/dei479","volume":"21","author":"RB Sciurano","year":"2006","unstructured":"Sciurano RB, Rahn MI, Pigozzi MI, Olmedo SB, Solari AJ (2006) An azoospermic man with a double-strand DNA break-processing deficiency in the spermatocyte nuclei: case report. Hum Reprod 21(5):1194\u20131203. https:\/\/doi.org\/10.1093\/humrep\/dei479","journal-title":"Hum Reprod"},{"issue":"11","key":"10469_CR61","doi-asserted-by":"publisher","first-page":"698","DOI":"10.1038\/s41580-019-0152-0","volume":"20","author":"R Scully","year":"2019","unstructured":"Scully R, Panday A, Elango R, Willis NA (2019) DNA double-strand break repair-pathway choice in somatic mammalian cells. Nat Rev Mol Cell Biol 20(11):698\u2013714. https:\/\/doi.org\/10.1038\/s41580-019-0152-0","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"19","key":"10469_CR62","doi-asserted-by":"publisher","first-page":"9017","DOI":"10.1093\/nar\/gkw783","volume":"44","author":"JM Short","year":"2016","unstructured":"Short JM, Liu Y, Chen S, Soni N, Madhusudhan MS, Shivji MK, Venkitaraman AR (2016) High-resolution structure of the presynaptic RAD51 filament on single-stranded DNA by electron cryo-microscopy. Nucleic Acids Res 44(19):9017\u20139030. https:\/\/doi.org\/10.1093\/nar\/gkw783","journal-title":"Nucleic Acids Res"},{"key":"10469_CR63","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.dnarep.2019.01.006","volume":"75","author":"V Singh","year":"2019","unstructured":"Singh V, Jaiswal D, Singh K, Trivedi S, Agrawal NK, Gupta G, Rajender S, Singh K (2019) Azoospermic infertility is associated with altered expression of DNA repair genes. DNA Repair 75:39\u201347. https:\/\/doi.org\/10.1016\/j.dnarep.2019.01.006","journal-title":"DNA Repair"},{"issue":"8","key":"10469_CR64","doi-asserted-by":"publisher","first-page":"107686","DOI":"10.1016\/j.celrep.2020.107686","volume":"31","author":"K Takemoto","year":"2020","unstructured":"Takemoto K, Tani N, Takada-Horisawa Y, Fujimura S, Tanno N, Yamane M, Okamura K, Sugimoto M, Araki K, Ishiguro KI (2020) Meiosis-specific C19orf57\/4930432K21Rik\/BRME1 modulates localization of RAD51 and DMC1 to DSBs in mouse meiotic recombination. Cell Rep 31(8):107686. https:\/\/doi.org\/10.1016\/j.celrep.2020.107686","journal-title":"Cell Rep"},{"key":"10469_CR65","doi-asserted-by":"publisher","unstructured":"Thomas M, Dubacq C, Rabut E, Lopez BS, Guirouilh-Barbat J (2023) Noncanonical Roles of RAD51. Cells 12(8): 1169. https:\/\/doi.org\/10.3390\/cells12081169","DOI":"10.3390\/cells12081169"},{"issue":"22","key":"10469_CR66","doi-asserted-by":"publisher","first-page":"3911","DOI":"10.1093\/hmg\/ddy286","volume":"27","author":"TN Tran","year":"2018","unstructured":"Tran TN, Schimenti JC (2018) A putative human infertility allele of the meiotic recombinase DMC1 does not affect fertility in mice. Hum Mol Genet 27(22):3911\u20133918. https:\/\/doi.org\/10.1093\/hmg\/ddy286","journal-title":"Hum Mol Genet"},{"issue":"13","key":"10469_CR67","doi-asserted-by":"publisher","first-page":"6236","DOI":"10.1073\/pnas.93.13.6236","volume":"93","author":"T Tsuzuki","year":"1996","unstructured":"Tsuzuki T, Fujii Y, Sakumi K, Tominaga Y, Nakao K, Sekiguchi M, Matsushiro A, Yoshimura Y, Morita T (1996) Targeted disruption of the Rad51 gene leads to lethality in embryonic mice. Proc Natl Acad Sci USA 93(13):6236\u20136240. https:\/\/doi.org\/10.1073\/pnas.93.13.6236","journal-title":"Proc Natl Acad Sci USA"},{"issue":"2","key":"10469_CR68","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/j.rbmo.2012.10.016","volume":"26","author":"H Wang","year":"2013","unstructured":"Wang H, Sun M, Qin Y, Xia T, Ma J, Chen ZJ (2013) Mutations in DMC1 are not responsible for premature ovarian failure in chinese women. Reprod Biomed Online 26(2):175\u2013178. https:\/\/doi.org\/10.1016\/j.rbmo.2012.10.016","journal-title":"Reprod Biomed Online"},{"issue":"10","key":"10469_CR69","doi-asserted-by":"publisher","first-page":"e0165198","DOI":"10.1371\/journal.pone.0165198","volume":"11","author":"M Wang","year":"2016","unstructured":"Wang M, Yu T, Hu L, Cheng Z, Li M (2016) Ubiquitin carboxy-terminal hydrolasel3 correlates with human sperm count, motility and fertilization. PLoS ONE 11(10):e0165198. https:\/\/doi.org\/10.1371\/journal.pone.0165198","journal-title":"PLoS ONE"},{"issue":"5","key":"10469_CR70","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1038\/s41419-018-0492-2","volume":"9","author":"JJ Wang","year":"2018","unstructured":"Wang JJ, Yu XW, Wu RY, Sun XF, Cheng SF, Ge W, Liu JC, Li YP, Liu J, Zou SH, De Felici M (2018) Starvation during pregnancy impairs fetal oogenesis and folliculogenesis in offspring in the mouse. Cell Death Dis 9(5):452. https:\/\/doi.org\/10.1038\/s41419-018-0492-2","journal-title":"Cell Death Dis"},{"issue":"7","key":"10469_CR72","doi-asserted-by":"publisher","first-page":"3525","DOI":"10.1093\/nar\/gkaa101","volume":"48","author":"Z Wang","year":"2020","unstructured":"Wang Z, Liu CY, Zhao Y, Dean J (2020) FIGLA, LHX8 and SOHLH1 transcription factor networks regulate mouse oocyte growth and differentiation. Nucleic Acids Res 48(7):3525\u20133541. https:\/\/doi.org\/10.1093\/nar\/gkaa101","journal-title":"Nucleic Acids Res"},{"issue":"6","key":"10469_CR71","doi-asserted-by":"publisher","first-page":"gaac015","DOI":"10.1093\/molehr\/gaac015","volume":"28","author":"W Wang","year":"2022","unstructured":"Wang W, Meng L, He J, Su L, Li Y, Tan C, Xu X, Nie H, Zhang H, Du J, Lu G (2022) Bi-allelic variants in SHOC1 cause non-obstructive azoospermia with meiosis arrest in humans and mice. Mol Hum Reprod 28(6):gaac015. https:\/\/doi.org\/10.1093\/molehr\/gaac015","journal-title":"Mol Hum Reprod"},{"issue":"10","key":"10469_CR73","first-page":"6585","volume":"7","author":"Y Xie","year":"2014","unstructured":"Xie Y, Cui D, Kong Y (2014) FoxM1 influences embryo implantation and is regulated by 17 beta-estradiol and progesterone in mouse uteri and endometrium cells. Int J Clin Exp Pathol 7(10):6585","journal-title":"Int J Clin Exp Pathol"},{"issue":"3","key":"10469_CR74","doi-asserted-by":"publisher","first-page":"e1008655","DOI":"10.1371\/journal.pgen.1008655","volume":"16","author":"H Xie","year":"2020","unstructured":"Xie H, Kang Y, Wang S, Zheng P, Chen Z, Roy S, Zhao C (2020) E2f5 is a versatile transcriptional activator required for spermatogenesis and multiciliated cell differentiation in zebrafish. PLoS Genet 16(3):e1008655. https:\/\/doi.org\/10.1371\/journal.pgen.1008655","journal-title":"PLoS Genet"},{"issue":"9","key":"10469_CR75","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1136\/jmedgenet-2017-105145","volume":"55","author":"Y Yang","year":"2018","unstructured":"Yang Y, Guo J, Dai L, Zhu Y, Hu H, Tan L, Chen W, Liang D, He J, Tu M, Wang K (2018) XRCC2 mutation causes meiotic arrest, azoospermia and infertility. J Med Genet 55(9):628\u2013636. https:\/\/doi.org\/10.1136\/jmedgenet-2017-105145","journal-title":"J Med Genet"},{"issue":"5","key":"10469_CR76","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1016\/S1097-2765(00)80070-2","volume":"1","author":"K Yoshida","year":"1998","unstructured":"Yoshida K, Kondoh G, Matsuda Y, Habu T, Nishimune Y, Morita T (1998) The mouse RecA-like gene Dmc1 is required for homologous chromosome synapsis during meiosis. Mol Cell 1(5):707\u2013718. https:\/\/doi.org\/10.1016\/S1097-2765(00)80070-2","journal-title":"Mol Cell"},{"key":"10469_CR77","doi-asserted-by":"publisher","first-page":"153061","DOI":"10.1016\/j.tox.2021.153061","volume":"467","author":"J Zhai","year":"2022","unstructured":"Zhai J, Geng W, Zhang T, Wei Y, He H, Chen W (2022) BDE-209 induce spermatocytes arrest at early-pachytene stage during meiotic prophase I in mice. Toxicology 467:153061. https:\/\/doi.org\/10.1016\/j.tox.2021.153061","journal-title":"Toxicology"},{"key":"10469_CR78","doi-asserted-by":"publisher","first-page":"113846","DOI":"10.1016\/j.ecoenv.2022.113846","volume":"242","author":"T Zhang","year":"2022","unstructured":"Zhang T, He H, Wei Y, Geng W, Zhai J (2022) Vitamin C supplementation rescued meiotic arrest of spermatocytes in Balb\/c mice exposed to BDE-209. Ecotoxicol Environ Saf 242:113846. https:\/\/doi.org\/10.1016\/j.ecoenv.2022.113846","journal-title":"Ecotoxicol Environ Saf"},{"issue":"10","key":"10469_CR79","doi-asserted-by":"publisher","first-page":"1705","DOI":"10.1038\/s12276-020-00519-1","volume":"52","author":"F Zhao","year":"2020","unstructured":"Zhao F, Kim W, Kloeber JA, Lou Z (2020) DNA end resection and its role in DNA replication and DSB repair choice in mammalian cells. Exp Mol Med 52(10):1705\u20131714. https:\/\/doi.org\/10.1038\/s12276-020-00519-1","journal-title":"Exp Mol Med"}],"container-title":["Biochemical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10528-023-10469-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10528-023-10469-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10528-023-10469-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,19]],"date-time":"2024-04-19T08:12:50Z","timestamp":1713514370000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10528-023-10469-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,10]]},"references-count":79,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["10469"],"URL":"https:\/\/doi.org\/10.1007\/s10528-023-10469-8","relation":{},"ISSN":["0006-2928","1573-4927"],"issn-type":[{"type":"print","value":"0006-2928"},{"type":"electronic","value":"1573-4927"}],"subject":[],"published":{"date-parts":[[2023,8,10]]},"assertion":[{"value":"15 June 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 July 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 August 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}},{"value":"This study was conducted after approval by the Institutional Ethics Committee, Guru Nanak Dev University, Amritsar, Punjab, India in accordance with the tenets of the Declaration of Helsinki (Letter No: 301\/HG dated 07-04-2022). Informed consent was obtained from all participants before conducting the study. The methodology was in accordance with guidelines and regulations of Indian Council of Medical Research (ICMR) National Ethical Guidelines for Biomedical and Health Research for human subjects.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval and Consent to Participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Publish"}}]}}