{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T19:59:08Z","timestamp":1780775948182,"version":"3.54.1"},"reference-count":112,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,3,21]],"date-time":"2024-03-21T00:00:00Z","timestamp":1710979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,3,21]],"date-time":"2024-03-21T00:00:00Z","timestamp":1710979200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Council of Scientific & Industrial Research, India","award":["09\/254(0300)\/2019-EMR-I"],"award-info":[{"award-number":["09\/254(0300)\/2019-EMR-I"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Biochem Genet"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1007\/s10528-024-10743-3","type":"journal-article","created":{"date-parts":[[2024,3,21]],"date-time":"2024-03-21T19:02:28Z","timestamp":1711047748000},"page":"730-760","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["XRCC1 Polymorphisms p.Arg194Trp, p.Arg280His, and p.Arg399Gln, Polycyclic Aromatic Hydrocarbons, and Infertility: A Case\u2013Control and In Silico Study"],"prefix":"10.1007","volume":"63","author":[{"given":"Jatinder Singh","family":"Sahota","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamlesh","family":"Guleria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6648-1906","authenticated-orcid":false,"given":"Vasudha","family":"Sambyal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,3,21]]},"reference":[{"key":"10743_CR1","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1093\/clinchem\/36.2.261","volume":"36","author":"K Adeli","year":"1990","unstructured":"Adeli K, Ogbonna G (1990) Rapid purification of human DNA from whole blood for potential application in clinical chemistry laboratories. Clin Chem 36:261\u2013264. https:\/\/doi.org\/10.1093\/clinchem\/36.2.261","journal-title":"Clin Chem"},{"key":"10743_CR2","doi-asserted-by":"publisher","first-page":"380","DOI":"10.22037\/uj.v0i0.4435","volume":"16","author":"H Akbas","year":"2019","unstructured":"Akbas H, Balkan M, Binici M, Gedik A (2019) The possible role of XRCC1 gene polymorphisms with idiopathic non-obstructive azoospermia in Southeast Turkey. Urol J 16:380\u2013385. https:\/\/doi.org\/10.22037\/uj.v0i0.4435","journal-title":"Urol J"},{"key":"10743_CR3","doi-asserted-by":"publisher","first-page":"629","DOI":"10.4238\/vol9-2gmr779","volume":"9","author":"R Attar","year":"2010","unstructured":"Attar R, Cacina C, Sozen S, Attar E, Agachan B (2010) DNA repair genes in endometriosis. Genet Mol Res 9:629\u2013636. https:\/\/doi.org\/10.4238\/vol9-2gmr779","journal-title":"Genet Mol Res"},{"key":"10743_CR4","first-page":"326","volume":"50","author":"D Bau","year":"2007","unstructured":"Bau D, Hsieh Y, Wan L, Wang R, Liao C, Lee C, Lin C, Tsai C, Tsai F (2007) Polymorphism of XRCC1 codon arg 399 Gln is associated with higher susceptibility to endometriosis. Chin J Physiol 50:326","journal-title":"Chin J Physiol"},{"key":"10743_CR5","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1158\/1055-9965.EPI-04-0566","volume":"14","author":"KA Bocskay","year":"2005","unstructured":"Bocskay KA, Tang D, Orjuela MA, Liu X, Warburton DP, Perera FP (2005) Chromosomal aberrations in cord blood are associated with prenatal exposure to carcinogenic polycyclic aromatic hydrocarbons. Cancer Epidemiol Biomarkers Prev 14:506\u2013511. https:\/\/doi.org\/10.1158\/1055-9965.EPI-04-0566","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10743_CR6","doi-asserted-by":"publisher","first-page":"4836","DOI":"10.1093\/nar\/23.23.4836","volume":"23","author":"KW Caldecott","year":"1995","unstructured":"Caldecott KW, Tucker JD, Stanker LH, Thompson LH (1995) Characterization of the XRCC1-DNA ligase III complex in vitro and its absence from mutant hamster cells. Nucleic Acids Res 23:4836\u20134843. https:\/\/doi.org\/10.1093\/nar\/23.23.4836","journal-title":"Nucleic Acids Res"},{"issue":"9","key":"10743_CR7","doi-asserted-by":"publisher","first-page":"1648","DOI":"10.1128\/mcb.00134-15","volume":"35","author":"A Campalans","year":"2015","unstructured":"Campalans A, Moritz E, Kortulewski T, Biard D, Epe B, Radicella JP (2015) Interaction with OGG1 is required for efficient recruitment of XRCC1 to base excision repair and maintenance of genetic stability after exposure to oxidative stress. Mol Cell Biol 35(9):1648\u20131658. https:\/\/doi.org\/10.1128\/mcb.00134-15","journal-title":"Mol Cell Biol"},{"key":"10743_CR8","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1007\/s10549-004-1004-x","volume":"89","author":"P Chacko","year":"2005","unstructured":"Chacko P, Rajan B, Joseph T, Mathew BS, Radhakrishna Pillai M (2005) Polymorphisms in DNA repair gene XRCC1 and increased genetic susceptibility to breast cancer. Breast Cancer Res Treat 89:15\u201321. https:\/\/doi.org\/10.1007\/s10549-004-1004-x","journal-title":"Breast Cancer Res Treat"},{"key":"10743_CR9","doi-asserted-by":"publisher","first-page":"1300","DOI":"10.1002\/ijc.28152","volume":"133","author":"KM Chen","year":"2013","unstructured":"Chen KM, Guttenplan JB, Zhang SM, Aliaga C, Cooper TK, Sun YW, DelTondo J, Kosinska W, Sharma AK, Jiang K, Bruggeman R (2013) Mechanisms of oral carcinogenesis induced by dibenzo [a, l] pyrene: an environmental pollutant and a tobacco smoke constituent. Int J Cancer 133:1300\u20131309. https:\/\/doi.org\/10.1002\/ijc.28152","journal-title":"Int J Cancer"},{"key":"10743_CR10","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1080\/10406630490471483","volume":"24","author":"T Chetiyanukornkul","year":"2004","unstructured":"Chetiyanukornkul T, Toriba A, Kizu R, Hayakawa K (2004) Urinary 2-hydroxyfluorene and 1-hydroxypyrene levels in smokers and nonsmokers in Japan and Thailand. Polycycl Aromat Compd 24:467\u2013474. https:\/\/doi.org\/10.1080\/10406630490471483","journal-title":"Polycycl Aromat Compd"},{"key":"10743_CR11","doi-asserted-by":"publisher","first-page":"R15","DOI":"10.1530\/REP-16-0069","volume":"152","author":"JK Collins","year":"2016","unstructured":"Collins JK, Jones KT (2016) DNA damage responses in mammalian oocytes. Reproduction 152:R15\u2013R22. https:\/\/doi.org\/10.1530\/REP-16-0069","journal-title":"Reproduction"},{"key":"10743_CR12","doi-asserted-by":"publisher","first-page":"1914","DOI":"10.1073\/pnas.89.5.1914","volume":"89","author":"M Cosman","year":"1992","unstructured":"Cosman M, De Los SC, Fiala R, Hingerty BE, Singh SB, Ibanez V, Margulis LA, Live D, Geacintov NE, Broyde S (1992) Solution conformation of the major adduct between the carcinogen (+)-anti-benzo [a] pyrene diol epoxide and DNA. Proc Natl Acad Sci 89:1914\u20131918. https:\/\/doi.org\/10.1073\/pnas.89.5.1914","journal-title":"Proc Natl Acad Sci"},{"key":"10743_CR13","doi-asserted-by":"publisher","first-page":"3791","DOI":"10.1042\/BCJ20190798","volume":"476","author":"S Cupello","year":"2019","unstructured":"Cupello S, Lin Y, Yan S (2019) Distinct roles of XRCC1 in genome integrity in Xenopus egg extracts. Biochem J 476:3791\u20133804. https:\/\/doi.org\/10.1042\/BCJ20190798","journal-title":"Biochem J"},{"key":"10743_CR14","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1126\/science.274.5286.430","volume":"274","author":"MF Denissenko","year":"1996","unstructured":"Denissenko MF, Pao A, Tang MS, Pfeifer GP (1996) Preferential formation of benzo [a] pyrene adducts at lung cancer mutational hotspots in P53. Science 274:430\u2013432. https:\/\/doi.org\/10.1126\/science.274.5286.430","journal-title":"Science"},{"key":"10743_CR15","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1007\/s43188-023-00181-5","volume":"39","author":"A El-Sikaily","year":"2023","unstructured":"El-Sikaily A, Helal M, Nsonwu-Anyanwu AC, Azab H, Abd ElMoneim N, Farahat EOS, Saad A (2023) Impacts of PAH accumulation on reproductive hormones, indices of oxidative stress and BPDE-albumin adduct in women with recurrent pregnancy loss. Toxicol Res 39:517\u2013531. https:\/\/doi.org\/10.1007\/s43188-023-00181-5","journal-title":"Toxicol Res"},{"key":"10743_CR16","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1007\/s13353-016-0380-3","volume":"58","author":"B Ewa","year":"2017","unstructured":"Ewa B, Danuta M\u0160 (2017) Polycyclic aromatic hydrocarbons and PAH-related DNA adducts. J Appl Genet 58:321\u2013330. https:\/\/doi.org\/10.1007\/s13353-016-0380-3","journal-title":"J Appl Genet"},{"key":"10743_CR17","doi-asserted-by":"publisher","first-page":"1105","DOI":"10.1016\/j.dnarep.2013.08.015","volume":"12","author":"SA Gabel","year":"2013","unstructured":"Gabel SA, DeRose EF, London RE (2013) XRCC1 interaction with the REV1 C-terminal domain suggests a role in post replication repair. DNA Repair 12:1105\u20131113. https:\/\/doi.org\/10.1016\/j.dnarep.2013.08.015","journal-title":"DNA Repair"},{"key":"10743_CR18","doi-asserted-by":"publisher","DOI":"10.1111\/and.13115","volume":"50","author":"A Garcia-Rodriguez","year":"2018","unstructured":"Garcia-Rodriguez A, de la Casa M, Serrano M, Gos\u00e1lvez J, Roy Barcelona R (2018) Impact of polymorphism in DNA repair genes OGG1 and XRCC1 on seminal parameters and human male infertility. Andrologia 50:e13115. https:\/\/doi.org\/10.1111\/and.13115","journal-title":"Andrologia"},{"key":"10743_CR19","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/S1383-5718(02)00297-8","volume":"535","author":"L Gaspari","year":"2003","unstructured":"Gaspari L, Chang SS, Santella RM, Garte S, Pedotti P, Taioli E (2003) Polycyclic aromatic hydrocarbon-DNA adducts in human sperm as a marker of DNA damage and infertility. Mutat Res Genet Toxicol Environ Mutagen 535:155\u2013160. https:\/\/doi.org\/10.1016\/S1383-5718(02)00297-8","journal-title":"Mutat Res Genet Toxicol Environ Mutagen"},{"key":"10743_CR20","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1080\/19396368.2017.1374488","volume":"63","author":"H Ghasemi","year":"2017","unstructured":"Ghasemi H, Khodadadi I, Fattahi A, Moghimbeigi A, Tavilani H (2017) Polymorphisms of DNA repair genes XRCC1 and LIG4 and idiopathic male infertility. Syst Biol Reprod Med 63:382\u2013390. https:\/\/doi.org\/10.1080\/19396368.2017.1374488","journal-title":"Syst Biol Reprod Med"},{"key":"10743_CR21","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1093\/toxsci\/kfl021","volume":"92","author":"E Grlickova-Duzevik","year":"2006","unstructured":"Grlickova-Duzevik E, Wise SS, Munroe RC, Thompson WD, Wise JP Sr (2006) XRCC1 protects against particulate chromate\u2013induced chromosome damage and cytotoxicity in Chinese hamster ovary cells. Toxicol Sci 92:409\u2013415. https:\/\/doi.org\/10.1093\/toxsci\/kfl021","journal-title":"Toxicol Sci"},{"key":"10743_CR22","doi-asserted-by":"publisher","first-page":"743","DOI":"10.3892\/ijmm.20.5.743","volume":"20","author":"A Gu","year":"2007","unstructured":"Gu A, Ji G, Liang J, Xia Y, Lu N, Wu B, Wang W, Song L, Wang S, Wang X (2007a) DNA repair gene XRCC1 and XPD polymorphisms and the risk of idiopathic azoospermia in a Chinese population. Int J Mol Med 20:743\u2013747. https:\/\/doi.org\/10.3892\/ijmm.20.5.743","journal-title":"Int J Mol Med"},{"key":"10743_CR23","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1111\/j.1745-7262.2007.00325.x","volume":"9","author":"AH Gu","year":"2007","unstructured":"Gu AH, Liang J, Lu NX, Wu B, Xia YK, Lu CC, Song L, Wang SL, Wang XR (2007b) Association of XRCC1 gene polymorphisms with idiopathic azoospermia in a Chinese population. Asian J Androl 9:781\u2013786. https:\/\/doi.org\/10.1111\/j.1745-7262.2007.00325.x","journal-title":"Asian J Androl"},{"key":"10743_CR24","doi-asserted-by":"publisher","first-page":"1219","DOI":"10.22034\/APJCP.2017.18.5.1219","volume":"18","author":"G Gulbay","year":"2017","unstructured":"Gulbay G, Yesilada E, Celik O, Yologlu S (2017) The investigation of polymorphisms in DNA repair genes (XRCC1, APE1 and XPD) in women with polycystic ovary syndrome. Asian Pac J Cancer Prev 18:1219. https:\/\/doi.org\/10.22034\/APJCP.2017.18.5.1219","journal-title":"Asian Pac J Cancer Prev"},{"key":"10743_CR25","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/S1383-5718(03)00051-2","volume":"537","author":"S Horak","year":"2003","unstructured":"Horak S, Polanska J, Widlak P (2003a) Bulky DNA adducts in human sperm: relationship with fertility, semen quality, smoking, and environmental factors. Mutat Res Genet Toxicol Environ Mutagen 537:53\u201365. https:\/\/doi.org\/10.1016\/S1383-5718(03)00051-2","journal-title":"Mutat Res Genet Toxicol Environ Mutagen"},{"key":"10743_CR26","doi-asserted-by":"publisher","first-page":"197","DOI":"10.18388\/abp.2003_3727","volume":"50","author":"S Horak","year":"2003","unstructured":"Horak S, Pola\u0144ska J, Wid\u0142ak P (2003b) High levels of bulky DNA adducts in human sperm correlate with impaired fertility. Acta Biochim Pol 50:197\u2013203. https:\/\/doi.org\/10.18388\/abp.2003_3727","journal-title":"Acta Biochim Pol"},{"key":"10743_CR27","doi-asserted-by":"publisher","first-page":"869","DOI":"10.1016\/j.fertnstert.2007.07.1328","volume":"91","author":"YY Hsieh","year":"2009","unstructured":"Hsieh YY, Chang CC, Bau DT, Tsai FJ, Tsai CH, Chen CP (2009) The p21 codon 31\u2217 C-and DRD2 codon 313\u2217 T-related genotypes\/alleles, but not XRCC1 codon 399, hOGG1 codon 326, and DRD1-48 polymorphisms, are correlated with the presence of leiomyoma. Fertil Steril 91:869\u2013877. https:\/\/doi.org\/10.1016\/j.fertnstert.2007.07.1328","journal-title":"Fertil Steril"},{"key":"10743_CR28","doi-asserted-by":"publisher","first-page":"305","DOI":"10.3109\/09513590.2011.631624","volume":"28","author":"YY Hsieh","year":"2012","unstructured":"Hsieh YY, Chang CC, Chen SY, Chen CP, Lin WH, Tsai FJ (2012) XRCC1 399Arg-related genotype and allele, but not XRCC1 His107Arg, XRCC1 Trp194Arg, KCNQ2, AT1R, and hOGG1 polymorphisms, are associated with higher susceptibility of endometriosis. Gynecol Endocrinol 28:305\u2013309. https:\/\/doi.org\/10.3109\/09513590.2011.631624","journal-title":"Gynecol Endocrinol"},{"key":"10743_CR29","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1007\/s00420-005-0066-3","volume":"79","author":"PC Hsu","year":"2006","unstructured":"Hsu PC, Chen IY, Pan CH, Wu KY, Pan MH, Chen JR, Chen CJ, Chang-Chien GP, Hsu CH, Liu CS, Wu MT (2006) Sperm DNA damage correlates with polycyclic aromatic hydrocarbons biomarker in coke-oven workers. Int Arch Occup Environ Health 79:349\u2013356. https:\/\/doi.org\/10.1007\/s00420-005-0066-3","journal-title":"Int Arch Occup Environ Health"},{"key":"10743_CR30","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1093\/carcin\/22.6.917","volume":"22","author":"JJ Hu","year":"2001","unstructured":"Hu JJ, Smith TR, Miller MS, Mohrenweiser HW, Golden A, Case LD (2001) Amino acid substitution variants of APE1 and XRCC1 genes associated with ionizing radiation sensitivity. Carcinogenesis 22:917\u2013922. https:\/\/doi.org\/10.1093\/carcin\/22.6.917","journal-title":"Carcinogenesis"},{"issue":"1","key":"10743_CR31","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/0263-7855(96)00018-5","volume":"14","author":"W Humphrey","year":"1996","unstructured":"Humphrey W, Dalke A, Schulten K (1996) VMD: visual molecular dynamics. J Mol Graph 14(1):33\u201338. https:\/\/doi.org\/10.1016\/0263-7855(96)00018-5","journal-title":"J Mol Graph"},{"key":"10743_CR32","first-page":"1","volume":"92","author":"IARC Working Group on the Evaluation of Carcinogenic Risks to Humans","year":"2010","unstructured":"IARC Working Group on the Evaluation of Carcinogenic Risks to Humans (2010) Some non-heterocyclic polycyclic aromatic hydrocarbons and some related exposures. IARC Monogr Eval Carcinog Risks Hum 92:1\u2013853","journal-title":"IARC Monogr Eval Carcinog Risks Hum"},{"key":"10743_CR33","doi-asserted-by":"publisher","first-page":"349","DOI":"10.4149\/BLL_2019_057","volume":"120","author":"R Ibrahimi","year":"2019","unstructured":"Ibrahimi R, Musavi M, Shojaee M, Moossavi M, Moossavi SZ, Alaei M, Poodineh J, Ibrahimi M, Farahani Y, Khorasani M (2019) The polymorphism of XRCC1 Arg399Gln (rs25487) and male infertility risk: a meta-analysis of 1,407 cases and 974 control studies. Bratisl Lek Listy 120:349\u2013355. https:\/\/doi.org\/10.4149\/BLL_2019_057","journal-title":"Bratisl Lek Listy"},{"key":"10743_CR34","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.mrrev.2006.09.002","volume":"635","author":"S Jaroudi","year":"2007","unstructured":"Jaroudi S, SenGupta S (2007) DNA repair in mammalian embryos. Mutat Res\/rev Mutat Res 635:53\u201377. https:\/\/doi.org\/10.1016\/j.mrrev.2006.09.002","journal-title":"Mutat Res\/rev Mutat Res"},{"key":"10743_CR35","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1038\/269348a0","volume":"269","author":"AM Jeffrey","year":"1977","unstructured":"Jeffrey AM, Weinstein IB, Jennette KW, Grzeskowiak K, Nakanishi K, Harvey RG, Autrup H, Harris C (1977) Structures of benzo (a) pyrene\u2013nucleic acid adducts formed in human and bovine bronchial explants. Nature 269:348\u2013350. https:\/\/doi.org\/10.1038\/269348a0","journal-title":"Nature"},{"key":"10743_CR36","doi-asserted-by":"publisher","first-page":"W345","DOI":"10.1093\/nar\/gkz424","volume":"47","author":"L Jendele","year":"2019","unstructured":"Jendele L, Krivak R, Skoda P, Novotny M, Hoksza D (2019) PrankWeb: a web server for ligand binding site prediction and visualization. Nucleic Acids Res 47:W345\u2013W349. https:\/\/doi.org\/10.1093\/nar\/gkz424","journal-title":"Nucleic Acids Res"},{"key":"10743_CR37","doi-asserted-by":"publisher","first-page":"1586","DOI":"10.1093\/humrep\/deh836","volume":"20","author":"YT Jeon","year":"2005","unstructured":"Jeon YT, Kim JW, Park NH, Song YS, Kang SB, Lee HP (2005) DNA repair gene XRCC1 Arg399Gln polymorphism is associated with increased risk of uterine leiomyoma. Hum Reprod 20:1586\u20131589. https:\/\/doi.org\/10.1093\/humrep\/deh836","journal-title":"Hum Reprod"},{"key":"10743_CR38","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0013145","volume":"5","author":"G Ji","year":"2010","unstructured":"Ji G, Gu A, Zhou Y, Shi X, Xia Y, Long Y, Song L, Wang S, Wang X (2010a) Interactions between exposure to environmental polycyclic aromatic hydrocarbons and DNA repair gene polymorphisms on bulky DNA adducts in human sperm. PLoS ONE 5:e13145. https:\/\/doi.org\/10.1371\/journal.pone.0013145","journal-title":"PLoS ONE"},{"key":"10743_CR39","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1093\/toxsci\/kfq112","volume":"116","author":"G Ji","year":"2010","unstructured":"Ji G, Gu A, Zhu P, Xia Y, Zhou Y, Hu F, Song L, Wang S, Wang X (2010b) Joint effects of XRCC1 polymorphisms and polycyclic aromatic hydrocarbons exposure on sperm DNA damage and male infertility. Toxicol Sci 116:92\u201398. https:\/\/doi.org\/10.1093\/toxsci\/kfq112","journal-title":"Toxicol Sci"},{"issue":"1","key":"10743_CR40","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1186\/s12958-022-00920-7","volume":"20","author":"YS Jo","year":"2022","unstructured":"Jo YS, Ko HS, Kim AY, Jo HG, Kim WJ, Choi SK (2022) Effects of polycyclic aromatic hydrocarbons on the proliferation and differentiation of placental cells. Reprod Biol Endocrinol 20(1):47. https:\/\/doi.org\/10.1186\/s12958-022-00920-7","journal-title":"Reprod Biol Endocrinol"},{"key":"10743_CR41","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2022.114485","volume":"250","author":"B Kakavandi","year":"2023","unstructured":"Kakavandi B, Rafiemanesh H, Giannakis S, Beheshtaeen F, Samoili S, Hashemi M, Abdi F (2023) Establishing the relationship between Polycyclic Aromatic Hydrocarbons (PAHs) exposure and male infertility: a systematic review. Ecotoxicol Environ Saf 250:114485. https:\/\/doi.org\/10.1016\/j.ecoenv.2022.114485","journal-title":"Ecotoxicol Environ Saf"},{"key":"10743_CR42","doi-asserted-by":"publisher","first-page":"6593","DOI":"10.26355\/eurrev_202209_29759","volume":"26","author":"Z Kali","year":"2022","unstructured":"Kali Z, Cagiran FT, Kirici P, Dogan C, Celik O (2022) DNA repair gene (XRCC1 and XPD) polymorphism and risk of primary ovarian failure. Eur Rev Med Pharmacol Sci 26:6593\u20136599. https:\/\/doi.org\/10.26355\/eurrev_202209_29759","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"10743_CR43","doi-asserted-by":"publisher","first-page":"D1388","DOI":"10.1093\/nar\/gkaa971","volume":"49","author":"S Kim","year":"2021","unstructured":"Kim S, Chen J, Cheng T, Gindulyte A, He J, He S, Li Q, Shoemaker BA, Thiessen PA, Yu B, Zaslavsky L (2021) PubChem in 2021: new data content and improved web interfaces. Nucleic Acids Res 49:D1388\u2013D1395. https:\/\/doi.org\/10.1093\/nar\/gkaa971","journal-title":"Nucleic Acids Res"},{"key":"10743_CR44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1471-2105-13-198","volume":"13","author":"J Ko","year":"2012","unstructured":"Ko J, Park H, Seok C (2012) GalaxyTBM: template-based modeling by building a reliable core and refining unreliable local regions. BMC Bioinform 13:1\u20138. https:\/\/doi.org\/10.1186\/1471-2105-13-198","journal-title":"BMC Bioinform"},{"key":"10743_CR45","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a012583","volume":"5","author":"HE Krokan","year":"2013","unstructured":"Krokan HE, Bj\u00f8r\u00e5s M (2013) Base excision repair. Cold Spring Harb Perspect Biol 5:a012583. https:\/\/doi.org\/10.1101\/cshperspect.a012583","journal-title":"Cold Spring Harb Perspect Biol"},{"key":"10743_CR46","doi-asserted-by":"publisher","first-page":"204","DOI":"10.20517\/jtgg.2021.61","volume":"6","author":"FC Lam","year":"2022","unstructured":"Lam FC (2022) The DNA damage response-from cell biology to human disease. J Transl Genet Genom 6:204\u2013222. https:\/\/doi.org\/10.20517\/jtgg.2021.61","journal-title":"J Transl Genet Genom"},{"key":"10743_CR47","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0223725","volume":"14","author":"KJ Lee","year":"2019","unstructured":"Lee KJ, Piett CG, Andrews JF, Mann E, Nagel ZD, Gassman NR (2019) Defective base excision repair in the response to DNA damaging agents in triple negative breast cancer. PLoS ONE 14:e0223725. https:\/\/doi.org\/10.1371\/journal.pone.0223725","journal-title":"PLoS ONE"},{"key":"10743_CR48","doi-asserted-by":"publisher","first-page":"3177","DOI":"10.1093\/nar\/gkp144","volume":"37","author":"N Levy","year":"2009","unstructured":"Levy N, Oehlmann M, Delalande F, Nasheuer HP, Van Dorsselaer A, Schreiber V, de Murcia G, Menissier-de Murcia J, Maiorano D, Bresson A (2009) XRCC1 interacts with the p58 subunit of DNA Pol \u03b1-primase and may coordinate DNA repair and replication during S phase. Nucleic Acids Res 37:3177\u20133188. https:\/\/doi.org\/10.1093\/nar\/gkp144","journal-title":"Nucleic Acids Res"},{"key":"10743_CR49","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1080\/14647273.2018.1479888","volume":"23","author":"P Li","year":"2018","unstructured":"Li P, Hua R, Li K, Ma S, Wu B, Quan S, Yu Z (2018) Polycyclic aromatic hydrocarbons exposure and early miscarriage in women undergoing in vitro fertilization-embryo transfer. Hum Fertil 23:17\u201322. https:\/\/doi.org\/10.1080\/14647273.2018.1479888","journal-title":"Hum Fertil"},{"key":"10743_CR50","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000020008","volume":"99","author":"Z Liu","year":"2020","unstructured":"Liu Z, Lin L, Yao X, Xing J (2020) Association between polymorphisms in the XRCC1 gene and male infertility risk: a meta-analysis. Medicine 99:e20008. https:\/\/doi.org\/10.1097\/MD.0000000000020008","journal-title":"Medicine"},{"key":"10743_CR51","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1016\/j.dnarep.2015.02.005","volume":"30","author":"RE London","year":"2015","unstructured":"London RE (2015) The structural basis of XRCC1-mediated DNA repair. DNA Repair 30:90\u2013103. https:\/\/doi.org\/10.1016\/j.dnarep.2015.02.005","journal-title":"DNA Repair"},{"key":"10743_CR52","doi-asserted-by":"publisher","first-page":"S28","DOI":"10.1016\/S0027-5107(97)82687-5","volume":"379","author":"X Lowe","year":"1997","unstructured":"Lowe X, Panico E, Marchetti F, Wyrobek A (1997) Expression of DNA repair genes in unfertilized eggs and 2-cell embryos of mice. Mutat Res Genet Toxicol Environ Mutagen 379:S28\u2013S28. https:\/\/doi.org\/10.1016\/S0027-5107(97)82687-5","journal-title":"Mutat Res Genet Toxicol Environ Mutagen"},{"key":"10743_CR53","first-page":"2557","volume":"59","author":"RM Lunn","year":"1999","unstructured":"Lunn RM, Langlois RG, Hsieh LL, Thompson CL, Bell DA (1999) XRCC1 polymorphisms: effects on aflatoxin B1-DNA adducts and glycophorin A variant frequency. Cancer Res 59:2557\u20132561","journal-title":"Cancer Res"},{"key":"10743_CR54","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.ejogrb.2017.09.011","volume":"218","author":"MQ Lv","year":"2017","unstructured":"Lv MQ, Wang J, Yu XQ, Hong HH, Ren WJ, Ge P, Zhou DX (2017) Association between X-ray repair cross-complementing group 1 (XRCC1) Arg399Gln polymorphism and endometriosis: a systematic review and meta-analysis. Eur J Obstet Gynecol Reprod Biol 218:12\u201320. https:\/\/doi.org\/10.1016\/j.ejogrb.2017.09.011","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10743_CR55","doi-asserted-by":"publisher","DOI":"10.1111\/and.13700","volume":"52","author":"MQ Lv","year":"2020","unstructured":"Lv MQ, Li YX, Ge P, Yang YQ, Zhang J, Han SP, Zhou DX (2020) Association between X-ray repair cross-complementing group 1 Arg399Gln polymorphism and male infertility: an update meta-analysis. Andrologia 52:e13700. https:\/\/doi.org\/10.1111\/and.13700","journal-title":"Andrologia"},{"key":"10743_CR56","first-page":"77","volume":"3","author":"R Mandarapu","year":"2016","unstructured":"Mandarapu R, Konathala G (2016) Base excision repair pathway gene polymorphisms in South Indian population. Int J Contemp Med Res 3:77\u201383","journal-title":"Int J Contemp Med Res"},{"key":"10743_CR57","first-page":"85","volume":"18","author":"S Marzband","year":"2015","unstructured":"Marzband S, Mashayekhi F, Salehi Z, Bahadori MH (2015) Association of Arg399Gln polymorphism of XRCC1 with idiopathic male infertility in Guilan Province. J Arak Uni Med Sci 18:85\u201391","journal-title":"J Arak Uni Med Sci"},{"key":"10743_CR58","doi-asserted-by":"publisher","first-page":"203","DOI":"10.18869\/acadpub.ismj.19.2.203","volume":"19","author":"S Marzband","year":"2016","unstructured":"Marzband S, Mashayekhi F, Salehi Z, Bahadori M (2016) Analysis of XRCC1 Arg194Trp polymorphism and the risk of idiopathic male infertility. Iran South Med J 19:203\u2013211. https:\/\/doi.org\/10.18869\/acadpub.ismj.19.2.203","journal-title":"Iran South Med J"},{"key":"10743_CR59","doi-asserted-by":"publisher","first-page":"1437","DOI":"10.1093\/carcin\/22.9.1437","volume":"22","author":"G Matullo","year":"2001","unstructured":"Matullo G, Palli D, Peluso M, Guarrera S, Carturan S, Celentano E, Krogh V, Munnia A, Tumino R, Polidoro S, Piazza A (2001) XRCC1, XRCC3, XPD gene polymorphisms, smoking and 32 P-DNA adducts in a sample of healthy subjects. Carcinogenesis 22:1437\u20131445. https:\/\/doi.org\/10.1093\/carcin\/22.9.1437","journal-title":"Carcinogenesis"},{"key":"10743_CR60","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1093\/humupd\/dmz034","volume":"26","author":"L M\u00e9ar","year":"2020","unstructured":"M\u00e9ar L, Herr M, Fauconnier A, Pineau C, Vialard F (2020) Polymorphisms and endometriosis: a systematic review and meta-analyses. Hum Reprod Update 26:73\u2013103. https:\/\/doi.org\/10.1093\/humupd\/dmz034","journal-title":"Hum Reprod Update"},{"key":"10743_CR61","doi-asserted-by":"publisher","DOI":"10.1111\/and.13925","volume":"53","author":"A Metin Mahmutoglu","year":"2021","unstructured":"Metin Mahmutoglu A, Gunes S, Asci R, Henkel R, Aydin O (2021) Association of XRCC1 and ERCC2 promoters\u2019 methylation with chromatin condensation and sperm DNA fragmentation in idiopathic oligoasthenoteratozoospermic men. Andrologia 53:e13925. https:\/\/doi.org\/10.1111\/and.13925","journal-title":"Andrologia"},{"key":"10743_CR62","doi-asserted-by":"publisher","first-page":"636","DOI":"10.4238\/2014.January.28.9","volume":"13","author":"MS Monteiro","year":"2014","unstructured":"Monteiro MS, Boas DB, Gigliotti CB, Salvadori DMF (2014) Association among XRCC1, XRCC3, and BLHX gene polymorphisms and chromosome instability in lymphocytes from patients with endometriosis and ovarian cancer. Genet Mol Res 13:636\u2013648. https:\/\/doi.org\/10.4238\/2014.January.28.9","journal-title":"Genet Mol Res"},{"key":"10743_CR63","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1002\/0471250953.bi0814s24","volume":"24","author":"GM Morris","year":"2008","unstructured":"Morris GM, Huey R, Olson AJ (2008) Using autodock for ligand-receptor docking. Curr Protoc Bioinformatics 24:8\u201314. https:\/\/doi.org\/10.1002\/0471250953.bi0814s24","journal-title":"Curr Protoc Bioinformatics"},{"key":"10743_CR64","doi-asserted-by":"publisher","first-page":"1117155","DOI":"10.3389\/fcell.2023.1117155","volume":"11","author":"J Nayak","year":"2023","unstructured":"Nayak J, Jena SR, Kumar S, Kar S, Dixit A, Samanta L (2023) Human sperm proteome reveals the effect of environmental borne seminal polyaromatic hydrocarbons exposome in etiology of idiopathic male factor infertility. Front Cell Dev Biol 11:1117155. https:\/\/doi.org\/10.3389\/fcell.2023.1117155","journal-title":"Front Cell Dev Biol"},{"key":"10743_CR65","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1758-2946-3-33","volume":"3","author":"NM O'Boyle","year":"2011","unstructured":"O\u2019Boyle NM, Banck M, James CA, Morley C, Vandermeersch T, Hutchison GR (2011) Open Babel: an open chemical toolbox. J Cheminform 3:1\u201314. https:\/\/doi.org\/10.1186\/1758-2946-3-33","journal-title":"J Cheminform"},{"issue":"5","key":"10743_CR66","doi-asserted-by":"publisher","first-page":"3398","DOI":"10.3892\/mmr.2017.6396","volume":"15","author":"G Oliveri Conti","year":"2017","unstructured":"Oliveri Conti G, Calogero AE, Giacone F, Fiore M, Barchitta M, Agodi A, Ferrante M (2017) B(a)P adduct levels and fertility: a cross-sectional study in a Sicilian population. Mol Med Rep 15(5):3398\u20133404. https:\/\/doi.org\/10.3892\/mmr.2017.6396","journal-title":"Mol Med Rep"},{"key":"10743_CR67","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1016\/j.mrgentox.2010.08.004","volume":"703","author":"MA Orjuela","year":"2010","unstructured":"Orjuela MA, Liu X, Warburton D, Siebert AL, Cujar C, Tang D, Jobanputra V, Perera FP (2010) Prenatal PAH exposure is associated with chromosome-specific aberrations in cord blood. Mutat Res Genet Toxicol Environ Mutagen 703:108\u2013114. https:\/\/doi.org\/10.1016\/j.mrgentox.2010.08.004","journal-title":"Mutat Res Genet Toxicol Environ Mutagen"},{"issue":"13","key":"10743_CR68","doi-asserted-by":"publisher","first-page":"1605","DOI":"10.1002\/jcc.20084","volume":"25","author":"EF Pettersen","year":"2004","unstructured":"Pettersen EF, Goddard TD, Huang CC, Couch GS, Greenblatt DM, Meng EC, Ferrin TE (2004) UCSF Chimera\u2014A visualization system for exploratory research and analysis. J Comput Chem 25(13):1605\u20131612. https:\/\/doi.org\/10.1002\/jcc.20084","journal-title":"J Comput Chem"},{"key":"10743_CR69","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1016\/j.celrep.2018.12.082","volume":"26","author":"LM Polo","year":"2019","unstructured":"Polo LM, Xu Y, Hornyak P, Garces F, Zeng Z, Hailstone R, Matthews SJ, Caldecott KW, Oliver AW, Pearl LH (2019) Efficient single-strand break repair requires binding to both poly (ADP-ribose) and DNA by the central BRCT domain of XRCC1. Cell Rep 26:573\u2013581. https:\/\/doi.org\/10.1016\/j.celrep.2018.12.082","journal-title":"Cell Rep"},{"key":"10743_CR70","doi-asserted-by":"publisher","first-page":"2675","DOI":"10.3390\/ijerph8072675","volume":"8","author":"MM Pratt","year":"2011","unstructured":"Pratt MM, John K, MacLean AB, Afework S, Phillips DH, Poirier MC (2011) Polycyclic aromatic hydrocarbon (PAH) exposure and DNA adduct semi-quantitation in archived human tissues. Int J Environ Res Public Health 8:2675\u20132691. https:\/\/doi.org\/10.3390\/ijerph8072675","journal-title":"Int J Environ Res Public Health"},{"key":"10743_CR71","doi-asserted-by":"publisher","first-page":"6816","DOI":"10.1007\/s11356-015-5918-0","volume":"23","author":"LG Pruneda-\u00c1lvarez","year":"2016","unstructured":"Pruneda-\u00c1lvarez LG, P\u00e9rez-V\u00e1zquez FJ, Ru\u00edz-Vera T, Ochoa-Mart\u00ednez \u00c1C, Orta-Garc\u00eda ST, Jim\u00e9nez-Avalos JA, P\u00e9rez-Maldonado IN (2016) Urinary 1-hydroxypyrene concentration as an exposure biomarker to polycyclic aromatic hydrocarbons (PAHs) in Mexican women from different hot spot scenarios and health risk assessment. Environ Sci Pollut Res 23:6816\u20136825. https:\/\/doi.org\/10.1007\/s11356-015-5918-0","journal-title":"Environ Sci Pollut Res"},{"key":"10743_CR72","doi-asserted-by":"publisher","DOI":"10.1016\/j.dnarep.2020.102951","volume":"96","author":"E Rahimian","year":"2020","unstructured":"Rahimian E, Amini A, Alikarami F, Pezeshki SMS, Saki N, Safa M (2020) DNA repair pathways as guardians of the genome: therapeutic potential and possible prognostic role in hematologic neoplasms. DNA Repair 96:102951. https:\/\/doi.org\/10.1016\/j.dnarep.2020.102951","journal-title":"DNA Repair"},{"key":"10743_CR73","doi-asserted-by":"publisher","first-page":"105","DOI":"10.3390\/genes10020105","volume":"10","author":"J Ribas-Maynou","year":"2019","unstructured":"Ribas-Maynou J, Benet J (2019) Single and double strand sperm DNA damage: different reproductive effects on male fertility. Genes 10:105. https:\/\/doi.org\/10.3390\/genes10020105","journal-title":"Genes"},{"key":"10743_CR74","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.mrfmmm.2009.09.010","volume":"683","author":"J Rubes","year":"2010","unstructured":"Rubes J, Rybar R, Prinosilova P, Veznik Z, Chvatalova I, Solansky I, Sram RJ (2010) Genetic polymorphisms influence the susceptibility of men to sperm DNA damage associated with exposure to air pollution. Mutat Res Genet Toxicol Environ Mutagen 683:9\u201315. https:\/\/doi.org\/10.1016\/j.mrfmmm.2009.09.010","journal-title":"Mutat Res Genet Toxicol Environ Mutagen"},{"key":"10743_CR75","doi-asserted-by":"publisher","DOI":"10.5696\/2156-9614-9.21.190309","volume":"9","author":"AA Saad","year":"2019","unstructured":"Saad AA, Hussein T, El-Sikaily A, Abdel-Mohsen MA, Mokhamer EH, Youssef AI, Mohammed J (2019) Effect of polycyclic aromatic hydrocarbons exposure on sperm DNA in idiopathic male infertility. J Health Pollut 9:190309. https:\/\/doi.org\/10.5696\/2156-9614-9.21.190309","journal-title":"J Health Pollut"},{"key":"10743_CR76","doi-asserted-by":"publisher","first-page":"999","DOI":"10.9734\/BJMMR\/2015\/15811","volume":"6","author":"MA Safan","year":"2015","unstructured":"Safan MA, Ghanem AA (2015) Association between polymorphisms of XRCC1 and TP53 genes and endometriosis. Br J Med Med Res 6:999\u20131007. https:\/\/doi.org\/10.9734\/BJMMR\/2015\/15811","journal-title":"Br J Med Med Res"},{"key":"10743_CR77","first-page":"119","volume":"5","author":"P Salehian","year":"2015","unstructured":"Salehian P, Hassani M, Naderi M, Pooladi A (2015) Comparison of XRCC1Arg399Gln polymorphism in endometriosis and healthy women. NCMBJ 5:119\u2013125","journal-title":"NCMBJ"},{"key":"10743_CR78","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1159\/000366444","volume":"80","author":"K Saliminejad","year":"2015","unstructured":"Saliminejad K, Saket M, Kamali K, Memariani T, Khorshid HRK (2015) DNA repair gene XRCC1 and XRCC4 variations and risk of endometriosis: an association study. Gynecol Obstet Invest 80:85\u201388. https:\/\/doi.org\/10.1159\/000366444","journal-title":"Gynecol Obstet Invest"},{"issue":"2","key":"10743_CR79","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1021\/ci500588j","volume":"55","author":"T Sander","year":"2015","unstructured":"Sander T, Freyss J, von Korff M, Rufener C (2015) DataWarrior: an open-source program for chemistry aware data visualization and analysis. J Chem Inf Model 55(2):460\u2013473. https:\/\/doi.org\/10.1021\/ci500588j","journal-title":"J Chem Inf Model"},{"key":"10743_CR80","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1080\/10406630490472527","volume":"24","author":"A Seidel","year":"2004","unstructured":"Seidel A, Frank H, Behnke A, Schneider D, Jacob J (2004) Determination of dibenzo [a, l] pyrene and other fjord-region PAH isomers with MW 302 in environmental samples. Polycycl Aromat Compd 24:759\u2013771. https:\/\/doi.org\/10.1080\/10406630490472527","journal-title":"Polycycl Aromat Compd"},{"key":"10743_CR81","first-page":"604","volume":"58","author":"MR Shen","year":"1998","unstructured":"Shen MR, Jones IM, Mohrenweiser H (1998) Nonconservative amino acid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans. Cancer Res 58:604\u2013608","journal-title":"Cancer Res"},{"key":"10743_CR82","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1158\/1055-9965.EPI-04-0414","volume":"14","author":"J Shen","year":"2005","unstructured":"Shen J, Gammon MD, Terry MB, Wang L, Wang Q, Zhang F, Teitelbaum SL, Eng SM, Sagiv SK, Gaudet MM, Neugut AI (2005) Polymorphisms in XRCC1 modify the association between polycyclic aromatic hydrocarbon-DNA adducts, cigarette smoking, dietary antioxidants, and breast cancer risk. Cancer Epidemiol Biomarkers Prev 14:336\u2013342. https:\/\/doi.org\/10.1158\/1055-9965.EPI-04-0414","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10743_CR83","doi-asserted-by":"publisher","DOI":"10.1016\/j.genrep.2021.101238","volume":"24","author":"TA Sherchkova","year":"2021","unstructured":"Sherchkova TA, Grigoryan NA, Amelina MA, Lomteva SV, Alexandrova AA, Mashkina EV, Shkurat TP (2021) Role of XRCC1, XPC, NBN gene polymorphisms in spermatogenesis. Gene Rep 24:101238. https:\/\/doi.org\/10.1016\/j.genrep.2021.101238","journal-title":"Gene Rep"},{"key":"10743_CR84","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.bbapap.2015.10.004","volume":"1864","author":"A Singh","year":"2016","unstructured":"Singh A, Kaushik R, Mishra A, Shanker A, Jayaram B (2016) ProTSAV: a protein tertiary structure analysis and validation server. Biochim Biophys Acta Proteins Proteom 1864:11\u201319. https:\/\/doi.org\/10.1016\/j.bbapap.2015.10.004","journal-title":"Biochim Biophys Acta Proteins Proteom"},{"key":"10743_CR85","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1007\/s10815-018-1339-6","volume":"36","author":"V Singh","year":"2019","unstructured":"Singh V, Bansal SK, Sudhakar DVS, Chakraborty A, Trivedi S, Gupta G, Thangaraj K, Rajender S, Singh K (2019a) SNPs in ERCC1, ERCC2, and XRCC1 genes of the DNA repair pathway and risk of male infertility in the Asian populations: association study, meta-analysis, and trial sequential analysis. J Assist Reprod Genet 36:79\u201390. https:\/\/doi.org\/10.1007\/s10815-018-1339-6","journal-title":"J Assist Reprod Genet"},{"key":"10743_CR86","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.mrgentox.2019.01.004","volume":"839","author":"V Singh","year":"2019","unstructured":"Singh V, Mohanty SK, Verma P, Chakraborty A, Trivedi S, Rajender S, Singh K (2019b) XRCC1 deficiency correlates with increased DNA damage and male infertility. Mutat Res Genet Toxicol Environ Mutagen 839:1\u20138. https:\/\/doi.org\/10.1016\/j.mrgentox.2019.01.004","journal-title":"Mutat Res Genet Toxicol Environ Mutagen"},{"key":"10743_CR87","doi-asserted-by":"publisher","first-page":"1928","DOI":"10.1093\/bioinformatics\/btl268","volume":"22","author":"X Sol\u00e9","year":"2006","unstructured":"Sol\u00e9 X, Guin\u00f3 E, Valls J, Iniesta R, Moreno V (2006) SNPStats: a web tool for the analysis of association studies. Bioinformatics 22:1928\u20131929. https:\/\/doi.org\/10.1093\/bioinformatics\/btl268","journal-title":"Bioinformatics"},{"key":"10743_CR88","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1007\/s10311-007-0095-0","volume":"5","author":"K Srogi","year":"2007","unstructured":"Srogi K (2007) Monitoring of environmental exposure to polycyclic aromatic hydrocarbons: a review. Environ Chem Lett 5:169\u2013195. https:\/\/doi.org\/10.1007\/s10311-007-0095-0","journal-title":"Environ Chem Lett"},{"key":"10743_CR89","first-page":"125","volume":"10","author":"MC Stern","year":"2001","unstructured":"Stern MC, Umbach DM, van Gils CH, Lunn RM, Taylor JA (2001) DNA repair gene XRCC1 polymorphisms, smoking, and bladder cancer risk. Cancer Epidemiol Biomarkers Prev 10:125\u2013131","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10743_CR90","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4061\/2010\/780369","volume":"2010","author":"S Sterpone","year":"2010","unstructured":"Sterpone S, Cozzi R (2010) Influence of XRCC1 genetic polymorphisms on ionizing radiation-induced DNA damage and repair. J Nucleic Acids 2010:1\u20136. https:\/\/doi.org\/10.4061\/2010\/780369","journal-title":"J Nucleic Acids"},{"key":"10743_CR91","first-page":"13","volume":"7","author":"DL Sudakin","year":"2011","unstructured":"Sudakin DL, Stone DL, Power L (2011) Naphthalene mothballs: emerging and recurring issues and their relevance to environmental health. Curr Top Toxicol 7:13\u201319","journal-title":"Curr Top Toxicol"},{"key":"10743_CR92","doi-asserted-by":"publisher","first-page":"1621","DOI":"10.1158\/0008-5472.CAN-12-2929","volume":"73","author":"R Sultana","year":"2013","unstructured":"Sultana R, Abdel-Fatah T, Abbotts R, Hawkes C, Albarakati N, Seedhouse C, Ball G, Chan S, Rakha EA, Ellis IO, Madhusudan S (2013) Targeting XRCC1 deficiency in breast cancer for personalized therapy. Cancer Res 73:1621\u20131634. https:\/\/doi.org\/10.1158\/0008-5472.CAN-12-2929","journal-title":"Cancer Res"},{"key":"10743_CR93","doi-asserted-by":"publisher","first-page":"1084","DOI":"10.5958\/0973-0130.2019.00443.2","volume":"13","author":"LT Tajuldeen","year":"2019","unstructured":"Tajuldeen LT, Alshalah HH, Al-Hilli NM (2019) The Arg399Gln (rs25487) polymorphism of XRCC1 gene as a predictor for uterine leiomyoma in women of Babylon Province\/Iraq. Indian J Med Forensic Med Toxicol 13:1084\u20131090. https:\/\/doi.org\/10.5958\/0973-0130.2019.00443.2","journal-title":"Indian J Med Forensic Med Toxicol"},{"issue":"1\u20132","key":"10743_CR94","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/j.mrgentox.2005.01.007","volume":"582","author":"T Takanami","year":"2005","unstructured":"Takanami T, Nakamura J, Kubota Y, Horiuchi S (2005) The Arg280His polymorphism in X-ray repair cross-complementing gene 1 impairs DNA repair ability. Mutat Res Genet Toxicol Environ Mutagen 582(1\u20132):135\u2013145. https:\/\/doi.org\/10.1016\/j.mrgentox.2005.01.007","journal-title":"Mutat Res Genet Toxicol Environ Mutagen"},{"key":"10743_CR95","doi-asserted-by":"publisher","first-page":"2556","DOI":"10.1128\/MCB.22.8.2556-2563.2002","volume":"22","author":"RM Taylor","year":"2002","unstructured":"Taylor RM, Thistlethwaite A, Caldecott KW (2002) Central role for the XRCC1 BRCT I domain in mammalian DNA single-strand break repair. Mol Cell Biol 22:2556\u20132563. https:\/\/doi.org\/10.1128\/MCB.22.8.2556-2563.2002","journal-title":"Mol Cell Biol"},{"key":"10743_CR96","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1006\/dbio.1999.9232","volume":"208","author":"RS Tebbs","year":"1999","unstructured":"Tebbs RS, Flannery ML, Meneses JJ, Hartmann A, Tucker JD, Thompson LH, Cleaver JE, Pedersen RA (1999) Requirement for the Xrcc1 DNA base excision repair gene during early mouse development. Dev Biol 208:513\u2013529. https:\/\/doi.org\/10.1006\/dbio.1999.9232","journal-title":"Dev Biol"},{"issue":"19","key":"10743_CR97","doi-asserted-by":"publisher","first-page":"14411","DOI":"10.3390\/ijms241914411","volume":"24","author":"G Traini","year":"2023","unstructured":"Traini G, Tamburrino L, Ragosta ME, Guarnieri G, Morelli A, Vignozzi L, Baldi E, Marchiani S (2023) Effects of benzo [a] pyrene on human sperm functions: an in vitro study. Int J Mol Sci 24(19):14411. https:\/\/doi.org\/10.3390\/ijms241914411","journal-title":"Int J Mol Sci"},{"key":"10743_CR98","doi-asserted-by":"publisher","first-page":"6530","DOI":"10.1093\/emboj\/20.22.6530","volume":"20","author":"AE Vidal","year":"2001","unstructured":"Vidal AE, Boiteux S, Hickson ID, Radicella JP (2001) XRCC1 coordinates the initial and late stages of DNA Abasic site repair through protein\u2013protein interactions. EMBO J 20:6530\u20136539. https:\/\/doi.org\/10.1093\/emboj\/20.22.6530","journal-title":"EMBO J"},{"key":"10743_CR99","doi-asserted-by":"publisher","first-page":"3316","DOI":"10.1093\/nar\/gkg565","volume":"31","author":"L Willard","year":"2003","unstructured":"Willard L, Ranjan A, Zhang H, Monzavi H, Boyko RF, Sykes BD, Wishart DS (2003) VADAR: a web server for quantitative evaluation of protein structure quality. Nucleic Acids Res 31:3316\u20133319. https:\/\/doi.org\/10.1093\/nar\/gkg565","journal-title":"Nucleic Acids Res"},{"key":"10743_CR100","doi-asserted-by":"publisher","first-page":"4567","DOI":"10.1021\/es9000642","volume":"43","author":"Y Xia","year":"2009","unstructured":"Xia Y, Han Y, Zhu P, Wang S, Gu A, Wang L, Lu C, Fu G, Song L, Wang X (2009a) Relation between urinary metabolites of polycyclic aromatic hydrocarbons and human semen quality. Environmen Sci Technol 43:4567\u20134573. https:\/\/doi.org\/10.1021\/es9000642","journal-title":"Environmen Sci Technol"},{"key":"10743_CR101","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1093\/humrep\/dep006","volume":"24","author":"Y Xia","year":"2009","unstructured":"Xia Y, Zhu P, Han Y, Lu C, Wang S, Gu A, Fu G, Zhao R, Song L, Wang X (2009b) Urinary metabolites of polycyclic aromatic hydrocarbons in relation to idiopathic male infertility. Hum Reprod 24:1067\u20131074. https:\/\/doi.org\/10.1093\/humrep\/dep006","journal-title":"Hum Reprod"},{"key":"10743_CR102","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1590\/S1415-475738420140359","volume":"38","author":"M Yaghmaei","year":"2015","unstructured":"Yaghmaei M, Salimi S, Namazi L, Farajian-Mashhadi F (2015) Association of XRCC1 Arg399GIn and Tp53 Arg72Pro polymorphisms and increased risk of uterine leiomyoma-A case-control study. Genet Mol Biol 38:444\u2013449. https:\/\/doi.org\/10.1590\/S1415-475738420140359","journal-title":"Genet Mol Biol"},{"key":"10743_CR103","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1007\/s11010-009-0347-3","volume":"338","author":"Y Yang","year":"2010","unstructured":"Yang Y, Zhai XD, Gao LB, Li SL, Wang Z, Chen GD (2010) Genetic polymorphisms of DNA repair gene XRCC1 and risk of uterine leiomyoma. Mol Cell Biochem 338:143\u2013147. https:\/\/doi.org\/10.1007\/s11010-009-0347-3","journal-title":"Mol Cell Biochem"},{"issue":"2","key":"10743_CR104","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1038\/sj.cr.7290272","volume":"15","author":"Y Yong","year":"2005","unstructured":"Yong Y, He L (2005) SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci. Cell Res 15(2):97. https:\/\/doi.org\/10.1038\/sj.cr.7290272","journal-title":"Cell Res"},{"key":"10743_CR105","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0040131","volume":"7","author":"H Yu","year":"2012","unstructured":"Yu H, Zhao H, Wang LE, Liu Z, Li D, Wei Q (2012) Correlation between base-excision repair gene polymorphisms and levels of in-vitro BPDE\u2013Induced DNA adducts in cultured peripheral blood lymphocytes. PLoS ONE 7:e40131. https:\/\/doi.org\/10.1371\/journal.pone.0040131","journal-title":"PLoS ONE"},{"key":"10743_CR106","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/509215","volume":"2015","author":"YX Yun","year":"2015","unstructured":"Yun YX, Dai LP, Wang P, Wang KJ, Zhang JY, Xie W (2015) Association of polymorphisms in X-ray repair cross complementing 1 gene and risk of esophageal squamous cell carcinoma in a Chinese population. BioMed Res Int 2015:509215. https:\/\/doi.org\/10.1155\/2015\/509215","journal-title":"BioMed Res Int"},{"key":"10743_CR107","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1016\/S0015-0282(99)00230-7","volume":"72","author":"MT Zenzes","year":"1999","unstructured":"Zenzes MT, Bielecki R, Reed TE (1999a) Detection of benzo (a) pyrene diol epoxide\u2013DNA adducts in sperm of men exposed to cigarette smoke. Fertil Steril 72:330\u2013335. https:\/\/doi.org\/10.1016\/S0015-0282(99)00230-7","journal-title":"Fertil Steril"},{"key":"10743_CR108","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1093\/molehr\/5.2.125","volume":"5","author":"MT Zenzes","year":"1999","unstructured":"Zenzes MT, Puy LA, Bielecki R, Reed TE (1999b) Detection of benzo [a] pyrene diol epoxide-DNA adducts in embryos from smoking couples: evidence for transmission by spermatozoa. Mol Hum Reprod 5:125\u2013131. https:\/\/doi.org\/10.1093\/molehr\/5.2.125","journal-title":"Mol Hum Reprod"},{"key":"10743_CR109","doi-asserted-by":"publisher","first-page":"256","DOI":"10.7652\/jdyxb201602022","volume":"37","author":"J Zhang","year":"2016","unstructured":"Zhang J, Mo-qi L, Hui-hui H, Shui-ping H, Wen-bao Z, Liang Z, Dang-xia Z, He-cheng L (2016) XRCC1 rs25487 locus genetic polymorphisms and susceptibility to nonobstructive azoospermia in Hui minority ethnic population of Shaanxi province. Acad J Xian Jiaotong Univ 37:256\u2013259. https:\/\/doi.org\/10.7652\/jdyxb201602022","journal-title":"Acad J Xian Jiaotong Univ"},{"key":"10743_CR110","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1016\/j.rbmo.2012.06.014","volume":"25","author":"LR Zheng","year":"2012","unstructured":"Zheng LR, Wang XF, Zhou DX, Zhang J, Huo YW, Tian H (2012) Association between XRCC1 single-nucleotide polymorphisms and infertility with idiopathic azoospermia in northern Chinese Han males. Reprod Biomed Online 25:402\u2013407. https:\/\/doi.org\/10.1016\/j.rbmo.2012.06.014","journal-title":"Reprod Biomed Online"},{"key":"10743_CR111","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2021.118077","volume":"290","author":"S Zhou","year":"2021","unstructured":"Zhou S, Zhu Q, Liu H, Jiang S, Zhang X, Peng C, Yang G, Li J, Cheng L, Zhong R, Zeng Q (2021) Associations of polycyclic aromatic hydrocarbons exposure and its interaction with XRCC1 genetic polymorphism with lung cancer: a case-control study. Environ Pollut 290:118077. https:\/\/doi.org\/10.1016\/j.envpol.2021.118077","journal-title":"Environ Pollut"},{"key":"10743_CR112","doi-asserted-by":"publisher","first-page":"13582","DOI":"10.1021\/bi00041a038","volume":"34","author":"Y Zou","year":"1995","unstructured":"Zou Y, Liu TM, Geacintov NE, Van Houten B (1995) Interaction of the UvrABC nuclease system with a DNA duplex containing a single stereoisomer of dG-(+)-or dG-(-)-anti-BPDE. Biochemistry 34:13582\u201313593. https:\/\/doi.org\/10.1021\/bi00041a038","journal-title":"Biochemistry"}],"container-title":["Biochemical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10528-024-10743-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10528-024-10743-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10528-024-10743-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,17]],"date-time":"2025-02-17T22:58:13Z","timestamp":1739833093000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10528-024-10743-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,21]]},"references-count":112,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10743"],"URL":"https:\/\/doi.org\/10.1007\/s10528-024-10743-3","relation":{},"ISSN":["0006-2928","1573-4927"],"issn-type":[{"value":"0006-2928","type":"print"},{"value":"1573-4927","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,21]]},"assertion":[{"value":"27 September 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 February 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 March 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}},{"value":"This study was conducted after approval by the Institutional Ethics Committee, Guru Nanak Dev University, Amritsar, Punjab, India in accordance with the tenets of the Declaration of Helsinki (Letter No: 301\/HG dated 07-04-2022). Informed consent was obtained from all participants before conducting the study. The methodology was in accordance with guidelines and regulations of the Indian Council of Medical Research (ICMR) National Ethical Guidelines for Biomedical and Health Research for human subjects.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval and Consent to Participate"}}]}}