{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T06:13:30Z","timestamp":1791612810761,"version":"4.3.4"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2012,11,28]],"date-time":"2012-11-28T00:00:00Z","timestamp":1354060800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biotechnol Lett"],"published-print":{"date-parts":[[2013,3]]},"DOI":"10.1007\/s10529-012-1099-9","type":"journal-article","created":{"date-parts":[[2012,11,29]],"date-time":"2012-11-29T12:46:46Z","timestamp":1354193206000},"page":"423-429","source":"Crossref","is-referenced-by-count":16,"title":["Morphology engineering of Penicillium chrysogenum by RNA silencing of chitin synthase gene"],"prefix":"10.1007","volume":"35","author":[{"given":"Hui","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guohong","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genhai","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiming","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,11,28]]},"reference":[{"key":"1099_CR1","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1006\/fgbi.1996.0035","volume":"20","author":"PT Borgia","year":"1996","unstructured":"Borgia PT, Iartchouk N, Riggle PJ, Winter KR, Koltin Y, Bulawa CE (1996) The chsB gene of Aspergillus nidulans is necessary for normal hyphal growth and development. Fungal Genet Biol 20:193\u2013203","journal-title":"Fungal Genet Biol"},{"key":"1099_CR2","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1038\/nbt0195-58","volume":"13","author":"L Crawford","year":"1995","unstructured":"Crawford L, Stepan AM, McAda PC, Rambosek JA, Conder MJ, Vinci VA, Reeves CD (1995) Production of cephalosporin intermediates by feeding adipic acid to recombinant Penicillium chrysogenum strains expressing ring expansion activity. Biotechnology (New York) 13:58\u201362","journal-title":"Biotechnology (New York)"},{"key":"1099_CR3","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1128\/EC.00326-08","volume":"8","author":"K Fukuda","year":"2009","unstructured":"Fukuda K, Yamada K, Deoka K, Yamashita S, Ohta A, Horiuchi H (2009) Class III chitin synthase ChsB of Aspergillus nidulans localizes at the sites of polarized cell wall synthesis and is required for conidial development. Eukaryot Cell 8:945\u2013956","journal-title":"Eukaryot Cell"},{"key":"1099_CR4","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/s10295-005-0207-4","volume":"32","author":"TC McCarthy","year":"2005","unstructured":"McCarthy TC, Lalor E, Hanniffy O, Savage AV, Tuohy MG (2005) Comparison of wild-type and UV-mutant beta-glucanase-producing strains of Talaromyces emersonii with potential in brewing applications. J Ind Microbiol Biotechnol 32:125\u2013134","journal-title":"J Ind Microbiol Biotechnol"},{"key":"1099_CR5","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1099\/00221287-147-1-239","volume":"147","author":"M McIntyre","year":"2001","unstructured":"McIntyre M, Dynesen J, Nielsen J (2001) Morphological characterization of Aspergillus nidulans: growth, septation and fragmentation. Microbiology 147:239\u2013246","journal-title":"Microbiology"},{"key":"1099_CR6","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1046\/j.1365-2958.1996.5571084.x","volume":"20","author":"E Mellado","year":"1996","unstructured":"Mellado E, Aufauvre-Brown A, Gow NA, Holden DW (1996) The Aspergillus fumigatus chsC and chsG genes encode Class III chitin synthases with different functions. Mol Microbiol 20:667\u2013679","journal-title":"Mol Microbiol"},{"key":"1099_CR7","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.biotechadv.2003.09.005","volume":"22","author":"M Papagianni","year":"2004","unstructured":"Papagianni M (2004) Fungal morphology and metabolite production in submerged mycelial processes. Biotechnol Adv 22:189\u2013259","journal-title":"Biotechnol Adv"},{"key":"1099_CR8","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1002\/(SICI)1097-0290(19960905)51:5<558::AID-BIT8>3.3.CO;2-G","volume":"51","author":"GC Paul","year":"1996","unstructured":"Paul GC, Thomas CR (1996) A structured model for hyphal differentiation and penicillin production using Penicillium chrysogenum. Biotechnol Bioeng 51:558\u2013572","journal-title":"Biotechnol Bioeng"},{"key":"1099_CR9","volume-title":"United States pharmacopoeia 29 national formulary 24 (USP 29-NF 24)","author":"United States pharmacopeial convention","year":"2006","unstructured":"United States pharmacopeial convention (2006) United States pharmacopoeia 29 national formulary 24 (USP 29-NF 24). United State pharmacopeia, Rockville"},{"key":"1099_CR10","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/BF00508608","volume":"10","author":"JC Suijdam van","year":"1980","unstructured":"van Suijdam JC, Kossen NWF, Paul PG (1980) An inoculum technique for the production of fungal pellets. Eur J Appl Microbiol Biotechnol 10:211\u2013221","journal-title":"Eur J Appl Microbiol Biotechnol"},{"key":"1099_CR11","doi-asserted-by":"crossref","first-page":"1828","DOI":"10.1271\/bbb.58.1828","volume":"58","author":"K Yanai","year":"1994","unstructured":"Yanai K, Kojima N, Takaya N, Horiuchi H, Ohta A, Takagi M (1994) Isolation and characterization of two chitin synthase genes from Aspergillus nidulans. Biosci Biotechnol Biochem 58:1828\u20131835","journal-title":"Biosci Biotechnol Biochem"},{"key":"1099_CR12","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1002\/(SICI)1097-0290(19971220)56:6<593::AID-BIT1>3.0.CO;2-I","volume":"56","author":"TC Zangirolami","year":"1997","unstructured":"Zangirolami TC, Johansen CL, Nielsen J, Jorgensen SB (1997) Simulation of penicillin production in fed-batch cultivations using a morphologically structured model. Biotechnol Bioeng 56:593\u2013604","journal-title":"Biotechnol Bioeng"}],"container-title":["Biotechnology Letters"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10529-012-1099-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10529-012-1099-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10529-012-1099-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T20:04:55Z","timestamp":1559160295000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10529-012-1099-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11,28]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["1099"],"URL":"https:\/\/doi.org\/10.1007\/s10529-012-1099-9","relation":{},"ISSN":["0141-5492","1573-6776"],"issn-type":[{"value":"0141-5492","type":"print"},{"value":"1573-6776","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11,28]]}}}