{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T03:18:28Z","timestamp":1762917508259},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2014,2,22]],"date-time":"2014-02-22T00:00:00Z","timestamp":1393027200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biotechnol Lett"],"published-print":{"date-parts":[[2014,6]]},"DOI":"10.1007\/s10529-014-1487-4","type":"journal-article","created":{"date-parts":[[2014,2,21]],"date-time":"2014-02-21T10:59:25Z","timestamp":1392980365000},"page":"1217-1224","source":"Crossref","is-referenced-by-count":14,"title":["Lithium chloride inhibits TGF-\u03b21-induced myofibroblast transdifferentiation via PI3K\/Akt pathway in cultured fibroblasts from Tenon\u2019s capsule of the human eye"],"prefix":"10.1007","volume":"36","author":[{"given":"Eun Jee","family":"Chung","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong Ho","family":"Sohn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"So Hyun","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sun-Ah","family":"Jung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joon H.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,2,22]]},"reference":[{"key":"1487_CR1","doi-asserted-by":"crossref","first-page":"e25450","DOI":"10.1371\/journal.pone.0025450","volume":"6","author":"HA Baarsma","year":"2011","unstructured":"Baarsma HA, Spanjer AI, Haitsma G, Engelbertink LH, Meurs H, Jonker MR, Timens W, Postma DS, Kerstjens HA, Gosens R (2011) Activation of WNT\/beta-catenin signaling in pulmonary fibroblasts by TGF-beta(1) is increased in chronic obstructive pulmonary disease. PLoS One 6:e25450","journal-title":"PLoS One"},{"key":"1487_CR2","doi-asserted-by":"crossref","first-page":"3293","DOI":"10.1167\/iovs.10-6405","volume":"52","author":"SI Choi","year":"2011","unstructured":"Choi SI, Kim BY, Dadakhujaev S, Jester JV, Ryu H, Kim TI, Kim EK (2011) Inhibition of TGFBIp expression by lithium: implications for TGFBI-linked corneal dystrophy therapy. Invest Ophthalmol Vis Sci 52:3293\u20133300","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1487_CR3","doi-asserted-by":"crossref","first-page":"6232","DOI":"10.1167\/iovs.10-5747","volume":"51","author":"EJ Chung","year":"2010","unstructured":"Chung EJ, Moon SW, Jung SA, Cho YJ, Kim SW, Lee JH (2010) Potentiation of bortezomib-induced apoptosis by TGF-beta in cultured human Tenon\u2019s fibroblasts: contribution of the PI3K\/Akt signaling pathway. Invest Ophthalmol Vis Sci 51:6232\u20136237","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1487_CR4","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S1350-9462(01)00021-0","volume":"21","author":"MF Cordeiro","year":"2002","unstructured":"Cordeiro MF (2002) Beyond mitomycin: TGF-beta and wound healing. Prog Retin Eye Res 21:75\u201389","journal-title":"Prog Retin Eye Res"},{"key":"1487_CR5","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1042\/CS20020150","volume":"104","author":"MF Cordeiro","year":"2003","unstructured":"Cordeiro MF (2003) Role of transforming growth factor beta in conjunctival scarring. Clin Sci (Lond) 104:181\u2013187","journal-title":"Clin Sci (Lond)"},{"key":"1487_CR6","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1083\/jcb.122.1.103","volume":"122","author":"A Desmouliere","year":"1993","unstructured":"Desmouliere A, Geinoz A, Gabbiani F, Gabbiani G (1993) Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts. J Cell Biol 122:103\u2013111","journal-title":"J Cell Biol"},{"key":"1487_CR7","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0301-0082(01)00011-9","volume":"65","author":"CA Grimes","year":"2001","unstructured":"Grimes CA, Jope RS (2001) The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling. Prog Neurobiol 65:391\u2013426","journal-title":"Prog Neurobiol"},{"key":"1487_CR8","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1167\/iovs.04-0902","volume":"46","author":"S Grisanti","year":"2005","unstructured":"Grisanti S, Szurman P, Warga M, Kaczmarek R, Ziemssen F, Tatar O, Bartz-Schmidt KU (2005) Decorin modulates wound healing in experimental glaucoma filtration surgery: a pilot study. Invest Ophthalmol Vis Sci 46:191\u2013196","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1487_CR9","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/j.cellsig.2006.10.001","volume":"19","author":"JC Horowitz","year":"2007","unstructured":"Horowitz JC, Rogers DS, Sharma V, Vittal R, White ES, Cui Z, Thannickal VJ (2007) Combinatorial activation of FAK and AKT by transforming growth factor-beta1 confers an anoikis-resistant phenotype to myofibroblasts. Cell Signal 19:761\u2013771","journal-title":"Cell Signal"},{"key":"1487_CR10","doi-asserted-by":"crossref","first-page":"1822","DOI":"10.1016\/j.ophtha.2007.03.050","volume":"114","author":"P Khaw","year":"2007","unstructured":"Khaw P, Grehn F, Hollo G, Overton B, Wilson R, Vogel R, Smith Z (2007) A phase III study of subconjunctival human anti-transforming growth factor beta(2) monoclonal antibody (CAT-152) to prevent scarring after first-time trabeculectomy. Ophthalmology 114:1822\u20131830","journal-title":"Ophthalmology"},{"key":"1487_CR11","doi-asserted-by":"crossref","first-page":"L790","DOI":"10.1152\/ajplung.00099.2007","volume":"293","author":"MM Martin","year":"2007","unstructured":"Martin MM, Buckenberger JA, Jiang J, Malana GE, Knoell DL, Feldman DS, Elton TS (2007) TGF-beta1 stimulates human AT1 receptor expression in lung fibroblasts by cross talk between the Smad, p38 MAPK, JNK, and PI3K signaling pathways. Am J Physiol Lung Cell Mol Physiol 293:L790\u2013L799","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"1487_CR12","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1016\/S0002-9440(10)63247-6","volume":"165","author":"A Masszi","year":"2004","unstructured":"Masszi A, Fan L, Rosivall L, McCulloch CA, Rotstein OD, Mucsi I, Kapus A (2004) Integrity of cell\u2013cell contacts is a critical regulator of TGF-beta 1-induced epithelial-to-myofibroblast transition: role for beta-catenin. Am J Pathol 165:1955\u20131967","journal-title":"Am J Pathol"},{"key":"1487_CR13","doi-asserted-by":"crossref","first-page":"4895","DOI":"10.1167\/iovs.06-0118","volume":"47","author":"T Meyer-ter-Vehn","year":"2006","unstructured":"Meyer-ter-Vehn T, Sieprath S, Katzenberger B, Gebhardt S, Grehn F, Schlunck G (2006) Contractility as a prerequisite for TGF-beta-induced myofibroblast transdifferentiation in human tenon fibroblasts. Invest Ophthalmol Vis Sci 47:4895\u20134904","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1487_CR14","first-page":"206109","volume":"2012","author":"M Michalik","year":"2012","unstructured":"Michalik M, Wojcik KA, Jakiela B, Szpak K, Pierzchalska M, Sanak M, Madeja Z, Czyz J (2012) Lithium attenuates TGF-beta(1)-induced fibroblasts to myofibroblasts transition in bronchial fibroblasts derived from asthmatic patients. J Allergy (Cairo) 2012:206109","journal-title":"J Allergy (Cairo)"},{"key":"1487_CR15","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/S0092-8674(03)00432-X","volume":"113","author":"Y Shi","year":"2003","unstructured":"Shi Y, Massague J (2003) Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113:685\u2013700","journal-title":"Cell"},{"key":"1487_CR16","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1002\/path.2049","volume":"210","author":"RJ Stump","year":"2006","unstructured":"Stump RJ, Lovicu FJ, Ang SL, Pandey SK, McAvoy JW (2006) Lithium stabilizes the polarized lens epithelial phenotype and inhibits proliferation, migration, and epithelial mesenchymal transition. J Pathol 210:249\u2013257","journal-title":"J Pathol"},{"key":"1487_CR17","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/nrm809","volume":"3","author":"JJ Tomasek","year":"2002","unstructured":"Tomasek JJ, Gabbiani G, Hinz B, Chaponnier C, Brown RA (2002) Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat Rev Mol Cell Biol 3:349\u2013363","journal-title":"Nat Rev Mol Cell Biol"},{"key":"1487_CR18","doi-asserted-by":"crossref","first-page":"17901","DOI":"10.1074\/jbc.M111635200","volume":"277","author":"M Noort van","year":"2002","unstructured":"van Noort M, Meeldijk J, van der Zee R, Destree O, Clevers H (2002) Wnt signaling controls the phosphorylation status of beta-catenin. J Biol Chem 277:17901\u201317905","journal-title":"J Biol Chem"},{"key":"1487_CR19","doi-asserted-by":"crossref","first-page":"10431","DOI":"10.1158\/0008-5472.CAN-05-1522","volume":"65","author":"MC Wilkes","year":"2005","unstructured":"Wilkes MC, Mitchell H, Penheiter SG, Dore JJ, Suzuki K, Edens M, Sharma DK, Pagano RE, Leof EB (2005) Transforming growth factor-beta activation of phosphatidylinositol 3-kinase is independent of Smad2 and Smad3 and regulates fibroblast responses via p21-activated kinase-2. Cancer Res 65:10431\u201310440","journal-title":"Cancer Res"},{"key":"1487_CR20","doi-asserted-by":"crossref","first-page":"951","DOI":"10.3727\/096368909X471251","volume":"18","author":"W Young","year":"2009","unstructured":"Young W (2009) Review of lithium effects on brain and blood. Cell Transpl 18:951\u2013975","journal-title":"Cell Transpl"},{"key":"1487_CR21","first-page":"114","volume":"145","author":"K Zhang","year":"1994","unstructured":"Zhang K, Rekhter MD, Gordon D, Phan SH (1994) Myofibroblasts and their role in lung collagen gene expression during pulmonary fibrosis. A combined immunohistochemical and in situ hybridization study. Am J Pathol 145:114\u2013125","journal-title":"Am J Pathol"}],"container-title":["Biotechnology Letters"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10529-014-1487-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10529-014-1487-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10529-014-1487-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T16:05:05Z","timestamp":1559145905000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10529-014-1487-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2,22]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["1487"],"URL":"https:\/\/doi.org\/10.1007\/s10529-014-1487-4","relation":{},"ISSN":["0141-5492","1573-6776"],"issn-type":[{"value":"0141-5492","type":"print"},{"value":"1573-6776","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,2,22]]}}}