{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T04:08:20Z","timestamp":1744258100318,"version":"3.40.4"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2017,6,13]],"date-time":"2017-06-13T00:00:00Z","timestamp":1497312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2017,6,13]],"date-time":"2017-06-13T00:00:00Z","timestamp":1497312000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100003569","name":"Ministry of Food and Drug Safety","doi-asserted-by":"publisher","award":["14171MFDS227"],"award-info":[{"award-number":["14171MFDS227"]}],"id":[{"id":"10.13039\/501100003569","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Biotechnol Lett"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1007\/s10529-017-2372-8","type":"journal-article","created":{"date-parts":[[2017,6,13]],"date-time":"2017-06-13T08:27:35Z","timestamp":1497342455000},"page":"1375-1380","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Application of recombinant hemagglutinin proteins as alternative antigen standards for pandemic influenza vaccines"],"prefix":"10.1007","volume":"39","author":[{"given":"Yejin","family":"Choi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seong Yi","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ho Jung","family":"Oh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunbo","family":"Shim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seokkee","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hye Joo","family":"Chung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Do Keun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Younsang","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Younghee","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,6,13]]},"reference":[{"key":"2372_CR1","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1186\/1472-6750-12-77","volume":"12","author":"E Feshchenko","year":"2012","unstructured":"Feshchenko E, Rhodes DG, Felberbaum R, McPherson C, Rininger JA, Post P, Cox MM (2012) Pandemic influenza vaccine: characterization of A\/California\/07\/2009 (H1N1) recombinant hemagglutinin protein and insights into H1N1 antigen stability. BMC Biotechnol 12:77","journal-title":"BMC Biotechnol"},{"key":"2372_CR2","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.molmed.2010.05.002","volume":"16","author":"F Krammer","year":"2010","unstructured":"Krammer F, Grabherr R (2010) Alternative influenza vaccines made by insect cells. Trends Mol Med 16:313\u2013320","journal-title":"Trends Mol Med"},{"key":"2372_CR3","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1016\/j.biologicals.2009.12.004","volume":"38","author":"C Li","year":"2010","unstructured":"Li C, Shao M, Cui X, Song Y, Li J, Yuan L, Fang H, Liang Z, Cyr TD, Li F, Li X, Wang J (2010) Application of deglycosylation and electrophoresis to the quantification of influenza viral hemagglutinins facilitating the production of 2009 pandemic influenza (H1N1) vaccines at multiple manufacturing sites in China. Biologicals 38:284\u2013289","journal-title":"Biologicals"},{"key":"2372_CR4","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1016\/j.biologicals.2008.08.001","volume":"36","author":"CE McPherson","year":"2008","unstructured":"McPherson CE (2008) Development of a novel recombinant influenza vaccine in insect cells. Biologicals 36:350\u2013353","journal-title":"Biologicals"},{"key":"2372_CR5","doi-asserted-by":"publisher","first-page":"90","DOI":"10.3390\/vaccines3010090","volume":"3","author":"PD Minor","year":"2015","unstructured":"Minor PD (2015) Assaying the potency of influenza vaccines. Vaccines 3:90\u2013104","journal-title":"Vaccines"},{"key":"2372_CR6","doi-asserted-by":"publisher","first-page":"748","DOI":"10.1093\/clinids\/5.4.748","volume":"5","author":"GV Quinnan","year":"1983","unstructured":"Quinnan GV, Schooley R, Dolin R, Ennis FA, Gross P, Gwaltney JM (1983) Serologic responses and systemic reactions in adults after vaccination with monovalent A\/USSR\/77 and trivalent A\/USSR\/77, A\/Texas\/77, B\/Hong Kong\/72 influenza vaccines. Rev Infect Dis 5:748\u2013757","journal-title":"Rev Infect Dis"},{"key":"2372_CR7","doi-asserted-by":"publisher","first-page":"1223","DOI":"10.1086\/503050","volume":"193","author":"JJ Treanor","year":"2006","unstructured":"Treanor JJ, Schiff GM, Couch RB, Cate TR, Brady RC, Hay M, Wolff M, She D, Cox MM (2006) Dose-related safety and immunogenicity of a trivalent baculovirus-expressed influenza-virus hemagglutinin vaccine in elderly adults. J Infect Dis 193:1223\u20131228","journal-title":"J Infect Dis"},{"key":"2372_CR8","doi-asserted-by":"publisher","first-page":"7733","DOI":"10.1016\/j.vaccine.2011.07.128","volume":"29","author":"JJ Treanor","year":"2011","unstructured":"Treanor JJ, El Sahly H, King J, Graham I, Izikson R, Kohberger R, Patriarca P, Cox M (2011) Protective efficacy of a trivalent recombinant hemagglutinin protein vaccine (FluBlok\u00ae) against influenza in healthy adults: a randomized, placebo-controlled trial. Vaccine 29:7733\u20137739","journal-title":"Vaccine"},{"key":"2372_CR9","doi-asserted-by":"publisher","first-page":"5342","DOI":"10.1016\/j.vaccine.2015.08.077","volume":"33","author":"Y Wen","year":"2015","unstructured":"Wen Y, Han L, Palladino G, Ferrari A, Xie Y, Carfi A, Dormitzer RP, Settembre EC (2015) Conformationally selective biophysical assay for influenza vaccine potency determination. Vaccine 33:5342\u20135349","journal-title":"Vaccine"},{"key":"2372_CR10","unstructured":"WHO (2004) Guidelines on the use of vaccines and antivirals during influenza pandemics"},{"key":"2372_CR11","unstructured":"WHO (2011) Guidelines on regulatory preparedness for human pandemic influenza vaccines TRS 963"},{"key":"2372_CR12","unstructured":"WHO (2013a) Generic protocol for the calibration of seasonal and pandemic influenza antigen working reagents by WHO essential regulatory laboratories. TRS 979 Annex 5"},{"key":"2372_CR13","unstructured":"WHO (2013b) Antigenic and genetic characteristics of zoonotic influenza viruses and development of candidate vaccines viruses for pandemic preparedness"},{"key":"2372_CR14","unstructured":"WHO (2016) Influenza. World Health Organization Web. http:\/\/www.who.int\/biologicals\/vaccines\/influenza\/en\/. Accessed 12 Dec 2016"},{"key":"2372_CR15","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/S0092-1157(77)80008-5","volume":"5","author":"JM Wood","year":"1977","unstructured":"Wood JM, Schild GC, Newman RW, Seagroatt V (1977) An improved single-radial-immunodiffusion technique for the assay of influenza haemagglutinin antigen: application for potency determinations of inactivated whole virus and subunit vaccines. J Biol Stand 5:237\u2013242","journal-title":"J Biol Stand"}],"container-title":["Biotechnology Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10529-017-2372-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10529-017-2372-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10529-017-2372-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T04:50:58Z","timestamp":1744174258000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10529-017-2372-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,13]]},"references-count":15,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["2372"],"URL":"https:\/\/doi.org\/10.1007\/s10529-017-2372-8","relation":{},"ISSN":["0141-5492","1573-6776"],"issn-type":[{"type":"print","value":"0141-5492"},{"type":"electronic","value":"1573-6776"}],"subject":[],"published":{"date-parts":[[2017,6,13]]},"assertion":[{"value":"22 April 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 May 2017","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 June 2017","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}