{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T18:28:08Z","timestamp":1784226488900,"version":"3.55.0"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"6-7","license":[{"start":{"date-parts":[[2019,5,22]],"date-time":"2019-05-22T00:00:00Z","timestamp":1558483200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,5,22]],"date-time":"2019-05-22T00:00:00Z","timestamp":1558483200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Key Scientific Research Project of Universities of Henan Province, China","award":["19A330004"],"award-info":[{"award-number":["19A330004"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Biotechnol Lett"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1007\/s10529-019-02695-1","type":"journal-article","created":{"date-parts":[[2019,5,22]],"date-time":"2019-05-22T20:03:36Z","timestamp":1558555416000},"page":"867-872","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Recombinant lactococcus lactis secreting viral protein 1 of enterovirus 71 and its immunogenicity in mice"],"prefix":"10.1007","volume":"41","author":[{"given":"Pengwei","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinbiao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Tao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weidong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,5,22]]},"reference":[{"key":"2695_CR1","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1007\/s12602-014-9162-6","volume":"6","author":"I Al Kassaa","year":"2014","unstructured":"Al Kassaa I, Hober D, Hamze M, Chihib NE, Drider D (2014) Antiviral potential of lactic acid bacteria and their bacteriocins. Probiotics Antimicrob Proteins 6:177\u2013185","journal-title":"Probiotics Antimicrob Proteins"},{"key":"2695_CR2","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1186\/s12934-015-0313-6","volume":"14","author":"O Cano-Garrido","year":"2015","unstructured":"Cano-Garrido O, Seras-Franzoso J, Garcia-Fruitos E (2015) Lactic acid bacteria: reviewing the potential of a promising delivery live vector for biomedical purposes. Microb Cell Fact 14:137","journal-title":"Microb Cell Fact"},{"key":"2695_CR3","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1186\/1743-422X-9-26","volume":"9","author":"F Gao","year":"2012","unstructured":"Gao F, Wang Y, Mao Q, Yao X, Liu S, Li F, Zhu F, Yang J et al (2012) Enterovirus 71 viral capsid protein linear epitopes: identification and characterization. Virol J 9:26","journal-title":"Virol J"},{"key":"2695_CR4","doi-asserted-by":"publisher","first-page":"12084","DOI":"10.1128\/JVI.02189-15","volume":"89","author":"Z Ku","year":"2015","unstructured":"Ku Z, Ye X, Shi J, Wang X, Liu Q, Huang Z (2015) Single neutralizing monoclonal antibodies targeting the VP1 GH loop of enterovirus 71 inhibit both virus attachment and internalization during viral entry. J Virol 89:12084\u201312095","journal-title":"J Virol"},{"key":"2695_CR5","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1586\/erv.09.152","volume":"9","author":"MS Lee","year":"2010","unstructured":"Lee MS, Chang LY (2010) Development of enterovirus 71 vaccines. Expert Rev Vaccines 9:149\u2013156","journal-title":"Expert Rev Vaccines"},{"key":"2695_CR6","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1007\/s10295-018-2061-1","volume":"45","author":"L Li","year":"2018","unstructured":"Li L, Qiao X, Chen J, Zhang Y, Zheng Q, Hou J (2018) Surface-displayed porcine reproductive and respiratory syndrome virus from cell culture onto gram-positive enhancer matrix particles. J Ind Microbiol Biotechnol 45:889\u2013898","journal-title":"J Ind Microbiol Biotechnol"},{"key":"2695_CR7","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1586\/14760584.2016.1138862","volume":"15","author":"QY Mao","year":"2016","unstructured":"Mao QY, Wang Y, Bian L, Xu M, Liang Z (2016) EV71 vaccine, a new tool to control outbreaks of hand, foot and mouth disease (HFMD). Expert Rev Vaccines 15:599\u2013606","journal-title":"Expert Rev Vaccines"},{"key":"2695_CR8","doi-asserted-by":"publisher","first-page":"35","DOI":"10.14715\/cmb\/2016.62.13.7","volume":"62","author":"X Peng","year":"2016","unstructured":"Peng X, Fang X, Li J, Kong L, Li B, Ding X (2016) Enhancing immune responses of EV71 VP1 DNA vaccine by co-inoculating plasmid IL-12 or GM-CSF expressing vector in mice. Cell Mol Biol 62:35\u201341","journal-title":"Cell Mol Biol"},{"key":"2695_CR9","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1016\/j.clindermatol.2014.12.011","volume":"33","author":"D Ventarola","year":"2015","unstructured":"Ventarola D, Bordone L, Silverberg N (2015) Update on hand-foot-and-mouth disease. Clin Dermatol 33:340\u2013346","journal-title":"Clin Dermatol"},{"key":"2695_CR10","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1038\/nsmb.2255","volume":"19","author":"X Wang","year":"2012","unstructured":"Wang X, Peng W, Ren J, Hu Z, Xu J, Lou Z, Li X, Yin W et al (2012) A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71. Nat Struct Mol Biol 19:424\u2013429","journal-title":"Nat Struct Mol Biol"},{"key":"2695_CR11","doi-asserted-by":"publisher","first-page":"2967","DOI":"10.1007\/s00253-015-6498-0","volume":"99","author":"A Wyszynska","year":"2015","unstructured":"Wyszynska A, Kobierecka P, Bardowski J, Jagusztyn-Krynicka EK (2015) Lactic acid bacteria\u201320\u00a0years exploring their potential as live vectors for mucosal vaccination. Appl Microbiol Biotechnol 99:2967\u20132977","journal-title":"Appl Microbiol Biotechnol"},{"key":"2695_CR12","doi-asserted-by":"publisher","first-page":"4","DOI":"10.7774\/cevr.2017.6.1.4","volume":"6","author":"EJ Yi","year":"2017","unstructured":"Yi EJ, Shin YJ, Kim JH, Kim TG, Chang SY (2017) Enterovirus 71 infection and vaccines. Clin Exp Vaccine Res 6:4\u201314","journal-title":"Clin Exp Vaccine Res"},{"key":"2695_CR13","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1007\/s12026-015-8637-1","volume":"62","author":"J Yuan","year":"2015","unstructured":"Yuan J, Tang X, Yin K, Tian J, Rui K, Ma J, Mao C, Chen J et al (2015) GITRL as a genetic adjuvant enhances enterovirus 71 VP1 DNA vaccine immunogenicity. Immunol Res 62:81\u201388","journal-title":"Immunol Res"},{"key":"2695_CR14","first-page":"9262631","volume":"2018","author":"BY Zhou","year":"2018","unstructured":"Zhou BY, Sun JC, Li X, Zhang Y, Luo B, Jiang N, Liu MC (2018) Analysis of immune responses in mice orally immunized with recombinant pMG36e-SP-TSOL18\/Lactococcus lactis and pMG36e-TSOL18\/Lactococcus lactis vaccines of taenia solium. J Immunol Res 2018:9262631","journal-title":"J Immunol Res"}],"container-title":["Biotechnology Letters"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10529-019-02695-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10529-019-02695-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10529-019-02695-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,20]],"date-time":"2020-05-20T23:05:42Z","timestamp":1590015942000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10529-019-02695-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,22]]},"references-count":14,"journal-issue":{"issue":"6-7","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["2695"],"URL":"https:\/\/doi.org\/10.1007\/s10529-019-02695-1","relation":{},"ISSN":["0141-5492","1573-6776"],"issn-type":[{"value":"0141-5492","type":"print"},{"value":"1573-6776","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,22]]},"assertion":[{"value":"25 March 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 May 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 May 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"All authors declared that there is no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}