{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T00:00:02Z","timestamp":1791849602277,"version":"4.3.4"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T00:00:00Z","timestamp":1586304000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T00:00:00Z","timestamp":1586304000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Biotechnol Lett"],"published-print":{"date-parts":[[2020,8]]},"DOI":"10.1007\/s10529-020-02880-7","type":"journal-article","created":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T11:02:39Z","timestamp":1586343759000},"page":"1559-1566","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Analysis of main pathogenic bacteria and drug sensitivity in patients with chronic suppurative otitis media and middle ear cholesteatoma in China"],"prefix":"10.1007","volume":"42","author":[{"given":"Feng","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weili","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaojiao","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hailing","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,4,8]]},"reference":[{"key":"2880_CR1","volume-title":"Chronic suppurative otitis media: burden of illness and management options","author":"J Acuin","year":"2004","unstructured":"Acuin J (2004) Chronic suppurative otitis media: burden of illness and management options. World Health Organization, Geneve"},{"key":"2880_CR2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.5414\/CP201374","volume":"49","author":"YL Dong","year":"2011","unstructured":"Dong YL, Dong HY, Hu SS et al (2011) An assessment of teicoplanin use and monitoring serum levels in a Chinese teaching hospital. Int J Clin Pharm Ther 49:1\u201314","journal-title":"Int J Clin Pharm Ther"},{"key":"2880_CR3","first-page":"128","volume":"22","author":"YL Dong","year":"2012","unstructured":"Dong YL, Dong HY, Hu SS, Wang X, Wei YX, Wang MY, Dong WH, Yao HP, You HS, Xing JF (2012) Bacterial spectrum and their sensitivity pattern in patients of chronic suppurative otitis media. Int J Clin Pharmacol Ther 22:128\u2013129","journal-title":"Int J Clin Pharmacol Ther"},{"key":"2880_CR4","first-page":"336","volume":"19","author":"G Fenqi","year":"2018","unstructured":"Fenqi G, Line W, Shusheng G et al (2018) Cause analysis of non-dry ear after canal wall down mastoidectomy. J Clin Otorhinolaryngol Head Neck Surg 19:336\u2013369","journal-title":"J Clin Otorhinolaryngol Head Neck Surg"},{"key":"2880_CR5","first-page":"489","volume":"5","author":"X Gu","year":"2014","unstructured":"Gu X, Niu L, Keyonmu Y et al (2014) The Analysis of the Main Pathogenic Bacteria and Drug Sensitivity in Patients with Chronic Suppurative Otitis Media and Patients with Middle Ear Cholesteatoma in Xinjiang. J Audiol Speech Pathol 5:489\u2013493","journal-title":"J Audiol Speech Pathol"},{"key":"2880_CR6","volume-title":"Technologies for Development","author":"N Leeds","year":"2015","unstructured":"Leeds N, Singhal R, Paul J et al (2015) Scalable ecosystem solution to screen and treat patients with chronic infections and hearing loss in emerging markets. In: Hostettler S (ed) Technologies for Development. Springer, Cham"},{"key":"2880_CR7","first-page":"1","volume":"18","author":"N Listed","year":"1994","unstructured":"Listed N (1994) Implementation of the international statistical classification of diseases and related health problems, tenth revision (ICD-10). Epidemiol Bull 18:1\u20134","journal-title":"Epidemiol Bull"},{"key":"2880_CR8","first-page":"7","volume":"55","author":"A1 Maniu","year":"2014","unstructured":"Maniu A1, Harabagiu O, Perde Schrepler M, C\u0103tan\u0103 A, F\u0103nu\u0163\u0103 B, Mogoant\u0103 CA (2014) Molecular biology of cholesteatoma. Rom J Morphol Embryol 55:7\u201313","journal-title":"Rom J Morphol Embryol"},{"key":"2880_CR9","doi-asserted-by":"publisher","first-page":"272","DOI":"10.5152\/iao.2017.4049","volume":"13","author":"P1 Merkus","year":"2017","unstructured":"Merkus P1, Ten Tije FA, Stam M, Tan FML, Pauw RJ (2017) Implementation of the \u201cEAONO\/JOS definitions and classification of middle ear cholesteatoma\u201d\u2014from STAM to STAMCO. J Int Adv Otol 13:272\u2013275","journal-title":"J Int Adv Otol"},{"key":"2880_CR10","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1017\/S0022215117002249","volume":"132","author":"MR Mofatteh","year":"2018","unstructured":"Mofatteh MR, Shahabian Moghaddam F, Yousefi M, Namaei MH (2018) A study of bacterial pathogens and antibiotic susceptibility patterns in chronic suppurative otitis media. J Laryngol Otol 132:41\u201345","journal-title":"J Laryngol Otol"},{"key":"2880_CR11","doi-asserted-by":"publisher","first-page":"2538","DOI":"10.1128\/JCM.01068-16","volume":"54","author":"M Neeff","year":"2016","unstructured":"Neeff M, Biswas K, Hoggard M, Taylor MW, Douglas R (2016) Molecular microbiological profile of chronic suppurative otitis media. J Clin Microbiol 54:2538\u20132546","journal-title":"J Clin Microbiol"},{"key":"2880_CR12","doi-asserted-by":"publisher","first-page":"124","DOI":"10.4103\/2141-9248.153622","volume":"5","author":"FT Orji","year":"2015","unstructured":"Orji FT, Dike BO (2015) Observations on the current bacteriological profile of chronic suppurative otitis media in South Eastern Nigeria. Ann Med Health Sci Res 5:124\u2013128","journal-title":"Ann Med Health Sci Res"},{"key":"2880_CR13","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1007\/s10096-008-0478-6","volume":"27","author":"DC Park","year":"2008","unstructured":"Park DC, Lee SK, Cha CI, Lee SO, Lee MS, Yeo SG (2008) Antimicrobial resistance of staphylococcus from otorrhea in chronic suppurative otitis media and comparison with results of all isolated Staphylococci. Eur J Clin Microbiol Infect Dis 27:571\u2013577","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"2880_CR14","first-page":"1143","volume":"39","author":"MT Semaan","year":"2006","unstructured":"Semaan MT, Megerian CA (2006) The pathophysiology of cholesteatoma. Rev Laryngol Otol Rhinol (Bord) 39:1143\u20131159","journal-title":"Rev Laryngol Otol Rhinol (Bord)"},{"key":"2880_CR15","doi-asserted-by":"publisher","first-page":"1062","DOI":"10.1080\/00016480601126978","volume":"127","author":"SG Yeo","year":"2007","unstructured":"Yeo SG, Park DC, Hong SM, Cha CI, Kim MG (2007) Bacteriology of chronic suppurative otitis media\u2013a Multicenter study. Acta Otolaryngol 127:1062\u20131067","journal-title":"Acta Otolaryngol"},{"key":"2880_CR16","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1007\/s00405-012-1924-8","volume":"270","author":"E1 Yorganc\u0131lar","year":"2013","unstructured":"Yorganc\u0131lar E1, Yildirim M, Gun R, Bakir S, Tekin R, Gocmez C, Meric F, Topcu I (2013) Complications of chronic suppurative otitis media: a retrospective review. Eur Arch Otorhinolaryngol 270:69\u201376","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"2880_CR17","doi-asserted-by":"publisher","first-page":"1","DOI":"10.5152\/iao.2017.3363","volume":"13","author":"M1 Yung","year":"2017","unstructured":"Yung M1, Tono T, Olszewska E, Yamamoto Y, Sudhoff H, Sakagami M et al (2017) EAONO\/JOS joint consensus Statements on the definitions, classification and staging of middle ear cholesteatoma. J Int Adv Otol 13:1\u20138","journal-title":"J Int Adv Otol"}],"container-title":["Biotechnology Letters"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10529-020-02880-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10529-020-02880-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10529-020-02880-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,7]],"date-time":"2021-04-07T23:26:23Z","timestamp":1617837983000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10529-020-02880-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,8]]},"references-count":17,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["2880"],"URL":"https:\/\/doi.org\/10.1007\/s10529-020-02880-7","relation":{},"ISSN":["0141-5492","1573-6776"],"issn-type":[{"value":"0141-5492","type":"print"},{"value":"1573-6776","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,8]]},"assertion":[{"value":"4 October 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 March 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 April 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}