{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T17:28:17Z","timestamp":1793899697451,"version":"4.8.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T00:00:00Z","timestamp":1787184000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T00:00:00Z","timestamp":1787184000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Biotechnol Lett"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1007\/s10529-026-03774-w","type":"journal-article","created":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T13:32:43Z","timestamp":1787232763000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Ethephon elicitation enhances biomass accumulation and phycobiliprotein production in Arthrospira platensis"],"prefix":"10.1007","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7215-7750","authenticated-orcid":false,"given":"Mahnaz","family":"Hadizadeh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3736-8760","authenticated-orcid":false,"given":"Ali","family":"Sheykhinejad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,8,20]]},"reference":[{"key":"3774_CR1","doi-asserted-by":"publisher","first-page":"100235","DOI":"10.1016\/j.foohum.2024.100235","volume":"2","author":"KD Athiyappan","year":"2024","unstructured":"Athiyappan KD, Routray W, Paramasivan B (2024) Comprehensive review on cultivation, extraction, purification, and its application in food and allied industries. Food Human. 2:100235. https:\/\/doi.org\/10.1016\/j.foohum.2024.100235","journal-title":"Food Human."},{"issue":"2","key":"3774_CR2","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1083\/jcb.58.2.419","volume":"58","author":"A Bennett","year":"1973","unstructured":"Bennett A, Bogorad L (1973) Complementary chromatic adaptation in a filamentous blue-green alga. J Cell Biol 58(2):419\u2013435. https:\/\/doi.org\/10.1083\/jcb.58.2.419","journal-title":"J Cell Biol"},{"issue":"1\u20132","key":"3774_CR3","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"MM Bradford","year":"1976","unstructured":"Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72(1\u20132):248\u2013254. https:\/\/doi.org\/10.1016\/0003-2697(76)90527-3","journal-title":"Anal Biochem"},{"key":"3774_CR4","doi-asserted-by":"publisher","DOI":"10.1016\/j.rineng.2024.102644","volume":"23","author":"JE Contreras-Ropero","year":"2024","unstructured":"Contreras-Ropero JE, Barajas-Solano AF, Garc\u00eda-Mart\u00ednez JB, Barajas-Ferreira C, Zuorro A (2024) Optimization of phycobiliprotein biosynthesis in thermotolerant cyanobacteria through light parameter adjustment. Results Eng 23:102644. https:\/\/doi.org\/10.1016\/j.rineng.2024.102644","journal-title":"Results Eng"},{"key":"3774_CR5","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1016\/j.biortech.2016.09.093","volume":"221","author":"T Coward","year":"2016","unstructured":"Coward T, Fuentes-Grunewald C, Silkina A, Oatley-Radcliffe DL, Llewellyn G et al (2016) Utilising light-emitting diodes of specific narrow wavelengths for the optimization and co-production of multiple high-value compounds in Porphyridium purpureum. Biores Technol 221:607\u2013615. https:\/\/doi.org\/10.1016\/j.biortech.2016.09.093","journal-title":"Biores Technol"},{"issue":"11","key":"3774_CR6","doi-asserted-by":"publisher","first-page":"1696","DOI":"10.3390\/en10111696","volume":"10","author":"H Du","year":"2017","unstructured":"Du H, Ahmed F, Lin B, Li Z, Huang Y et al (2017) The effects of plant growth regulators on cell growth, protein, carotenoid, PUFAs and lipid production of Chlorella pyrenoidosa ZF strain. Energies 10(11):1696. https:\/\/doi.org\/10.3390\/en10111696","journal-title":"Energies"},{"issue":"1","key":"3774_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00253-008-1542-y","volume":"80","author":"NT Eriksen","year":"2008","unstructured":"Eriksen NT (2008) Production of phycocyanin\u2014a pigment with applications in biology, biotechnology, foods and medicine. Appl Microbiol Biotechnol 80(1):1\u201314. https:\/\/doi.org\/10.1007\/s00253-008-1542-y","journal-title":"Appl Microbiol Biotechnol"},{"key":"3774_CR8","doi-asserted-by":"publisher","first-page":"1583","DOI":"10.1007\/s00217-022-03987-z","volume":"248","author":"JF Fabre","year":"2022","unstructured":"Fabre JF, Niangoran NUF, Gaignard C, Buso D, Mouloungui Z et al (2022) Extraction, purification and stability of C-phycocyanin from Arthrospira platensis. Eur Food Res Technol 248:1583\u20131599. https:\/\/doi.org\/10.1007\/s00217-022-03987-z","journal-title":"Eur Food Res Technol"},{"issue":"3","key":"3774_CR9","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1016\/j.jff.2014.10.011","volume":"11","author":"B Fern\u00e1ndez-Rojas","year":"2014","unstructured":"Fern\u00e1ndez-Rojas B, Hern\u00e1ndez-Ju\u00e1rez J, Pedraza-Chaverri J (2014) Nutraceutical properties of phycocyanin. J Funct Foods 11(3):375\u2013392. https:\/\/doi.org\/10.1016\/j.jff.2014.10.011","journal-title":"J Funct Foods"},{"key":"3774_CR10","doi-asserted-by":"publisher","DOI":"10.1016\/j.algal.2019.101600","volume":"42","author":"M Hsieh-Lo","year":"2019","unstructured":"Hsieh-Lo M, Castillo G, Ochoa-Becerra MA, Mojica L (2019) Phycocyanin and phycoerythrin: strategies to improve production yield and chemical stability. Algal Res 42:101600. https:\/\/doi.org\/10.1016\/j.algal.2019.101600","journal-title":"Algal Res"},{"key":"3774_CR11","doi-asserted-by":"publisher","first-page":"187","DOI":"10.21660\/2019.61.89205","volume":"17","author":"S Kaewdam","year":"2019","unstructured":"Kaewdam S, Jaturonglumlert S, Varith J, Nitatwichit C, Narkprasom K (2019) Kinetic models for phycocyanin production by fed -batch cultivation of the Spirulina platensis. Int J GEOMATE. 17:187\u2013194. https:\/\/doi.org\/10.21660\/2019.61.89205","journal-title":"Int J GEOMATE."},{"key":"3774_CR12","doi-asserted-by":"publisher","first-page":"4807","DOI":"10.1021\/acs.jafc.6b00541","volume":"64","author":"S-H Kim","year":"2016","unstructured":"Kim S-H, Lim SR, Hong S-J, Cho B-K, Lee H et al (2016) Effect of ethephon as an ethylene-releasing compound on the metabolic profile of Chlorella vulgaris. J Agric Food Chem 64:4807\u20134816. https:\/\/doi.org\/10.1021\/acs.jafc.6b00541","journal-title":"J Agric Food Chem"},{"key":"3774_CR13","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.biortech.2017.12.046","volume":"252","author":"H Liu","year":"2018","unstructured":"Liu H, Chen H, Wang S, Liu Q, Li S et al (2018) Optimizing light distribution and controlling biomass concentration by continuously pre-harvesting Spirulina platensis for improving the microalgae production. Bioresour Technol 252:14\u201319. https:\/\/doi.org\/10.1016\/j.biortech.2017.12.046","journal-title":"Bioresour Technol"},{"issue":"2","key":"3774_CR14","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1111\/jipb.13355","volume":"66","author":"B Ma","year":"2023","unstructured":"Ma B, Ma T, Xian W, Hu B, Chu C (2023) Interplay between ethylene and nitrogen nutrition: how ethylene orchestrates nitrogen responses in plants. J Integr Plant Biol 66(2):399\u2013407. https:\/\/doi.org\/10.1111\/jipb.13355","journal-title":"J Integr Plant Biol"},{"issue":"5","key":"3774_CR15","doi-asserted-by":"publisher","first-page":"2187","DOI":"10.1007\/s10811-015-0756-5","volume":"28","author":"H Mansouri","year":"2016","unstructured":"Mansouri H, Talebizadeh B (2016) Effect of gibberellic acid on the cyanobacterium Nostoc linckia. J Appl Phycol 28(5):2187\u20132193. https:\/\/doi.org\/10.1007\/s10811-015-0756-5","journal-title":"J Appl Phycol"},{"issue":"3","key":"3774_CR16","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1111\/pre.12177","volume":"65","author":"H Mansouri","year":"2017","unstructured":"Mansouri H, Talebizadeh R (2017) Effects of indole-3-butyric acid on growth, pigments and UV-screening compounds in Nostoc linckia. Phycol Res 65(3):212\u2013216. https:\/\/doi.org\/10.1111\/pre.12177","journal-title":"Phycol Res"},{"key":"3774_CR17","doi-asserted-by":"publisher","DOI":"10.1016\/j.algal.2024.103468","volume":"79","author":"HSH Munawaroh","year":"2024","unstructured":"Munawaroh HSH, Gumilar GG, Pratiwi RN, Khoiriah SF, Ningrum A et al (2024) In silico antiviral properties of Spirulina platensis phycobiliprotein and phycobilin as natural inhibitor for SARS-CoV-2. Algal Res 79:103468. https:\/\/doi.org\/10.1016\/j.algal.2024.103468","journal-title":"Algal Res"},{"issue":"4","key":"3774_CR18","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1016\/j.tplants.2006.02.006","volume":"11","author":"R Pierik","year":"2006","unstructured":"Pierik R, Tholen D, Poorter H, Visser EJ, Voesenek LA (2006) The Janus face of ethylene: growth inhibition and stimulation. Trends Plant Sci 11(4):176\u2013183. https:\/\/doi.org\/10.1016\/j.tplants.2006.02.006","journal-title":"Trends Plant Sci"},{"issue":"25","key":"3774_CR19","doi-asserted-by":"publisher","first-page":"93","DOI":"10.5897\/JSPPR.9000043","volume":"2","author":"P Prabuthas","year":"2011","unstructured":"Prabuthas P, Majumdar S, Srivastav PP, Mishra HN (2011) Standardization of rapid and economical method for neutraceuticals extraction from algae. J Stored Prod Postharvest Res 2(25):93\u201396. https:\/\/doi.org\/10.5897\/JSPPR.9000043","journal-title":"J Stored Prod Postharvest Res"},{"key":"3774_CR20","doi-asserted-by":"publisher","DOI":"10.1016\/j.bej.2022.108640","volume":"187","author":"SK Sandybayeva","year":"2022","unstructured":"Sandybayeva SK, Kossalbayev BD, Zayadan BK, Sadvakasova AK, Bolatkhan K (2022) Prospects of cyanobacterial pigment production: biotechnological potential and optimization strategies. Biochem Eng J 187:108640. https:\/\/doi.org\/10.1016\/j.bej.2022.108640","journal-title":"Biochem Eng J"},{"issue":"1","key":"3774_CR21","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/j.pharep.2017.07.018","volume":"70","author":"EFE Silva","year":"2018","unstructured":"Silva EFE, Figueira FS, Lettnin AP, Carrett-Dias M, Filgueira DMVB (2018) C-phycocyanin: cellular targets, mechanisms of action and multi drug resistance in cancer. Pharmacol Rep 70(1):75\u201380. https:\/\/doi.org\/10.1016\/j.pharep.2017.07.018","journal-title":"Pharmacol Rep"},{"issue":"10","key":"3774_CR22","doi-asserted-by":"publisher","first-page":"264","DOI":"10.31083\/j.fbl2810264","volume":"28","author":"N Touzout","year":"2023","unstructured":"Touzout N, Ainas M, Alloti R, Boussahoua C, Douma A, Hassein-Bey AH, Brara Z, Tahraoui H, Zhang J, Abdeltif A (2023) Unveiling the impact of thiophanate-methyl on Arthrospira platensis: growth, photosynthetic pigments, biomolecules, and detoxification enzyme activities. Front Biosci-Landmark. 28(10):264. https:\/\/doi.org\/10.31083\/j.fbl2810264","journal-title":"Front Biosci-Landmark."},{"key":"3774_CR23","doi-asserted-by":"publisher","DOI":"10.1007\/s11270-025-08171-z","volume":"236","author":"N Touzout","year":"2025","unstructured":"Touzout N, Tahraoui H, Lekmine S, Benchidi T, Bouchibane M, Ahmad I, Mihoub A, Moussa H, Danish S, Amrane A (2025) Ecotoxicological risk assessment of erythromycin and thiophanate-methyl on growth, physiological and biochemical responses of Spirulina (Arthrospira platensis). Water Air Soil Pollut 236:564. https:\/\/doi.org\/10.1007\/s11270-025-08171-z","journal-title":"Water Air Soil Pollut"},{"issue":"7","key":"3774_CR24","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1007\/s00299-013-1421-6","volume":"32","author":"X Wang","year":"2025","unstructured":"Wang X, Wen H, Suprun A, Zhu H (2025) Ethylene signaling in regulating plant growth, development, and stress responses. Plant Cell Rep 32(7):1099\u20131109. https:\/\/doi.org\/10.1007\/s00299-013-1421-6","journal-title":"Plant Cell Rep"},{"key":"3774_CR25","doi-asserted-by":"publisher","DOI":"10.1016\/j.biortech.2020.124125","volume":"319","author":"BNR Winayu","year":"2021","unstructured":"Winayu BNR, Lai KT, Hsueh H-T, Chu H (2021) Production of phycobiliprotein and carotenoid by efficient extraction from Thermosynechococcus sp. CL-1 cultivation in swine wastewater. Bioresour Technol 319:124125. https:\/\/doi.org\/10.1016\/j.biortech.2020.124125","journal-title":"Bioresour Technol"},{"key":"3774_CR26","doi-asserted-by":"publisher","first-page":"1589","DOI":"10.21203\/rs.3.rs-2671883\/v1","volume":"4","author":"Z Xie","year":"2023","unstructured":"Xie Z, Ma S, Cao Y, Peng S, Zhang X (2023) Effects of six phytohormones on the growth behavior and cellular biochemical components of Chlorella vulgaris. J Appl Phycol 4:1589\u20131602. https:\/\/doi.org\/10.21203\/rs.3.rs-2671883\/v1","journal-title":"J Appl Phycol"}],"container-title":["Biotechnology Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10529-026-03774-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10529-026-03774-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10529-026-03774-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T17:04:07Z","timestamp":1793898247000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10529-026-03774-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,20]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["3774"],"URL":"https:\/\/doi.org\/10.1007\/s10529-026-03774-w","relation":{},"ISSN":["0141-5492","1573-6776"],"issn-type":[{"value":"0141-5492","type":"print"},{"value":"1573-6776","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,20]]},"assertion":[{"value":"12 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 July 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 August 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 August 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"105"}}