{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T10:13:10Z","timestamp":1788775990028,"version":"build-2803163510"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T00:00:00Z","timestamp":1788739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T00:00:00Z","timestamp":1788739200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32470058"],"award-info":[{"award-number":["32470058"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32072201"],"award-info":[{"award-number":["32072201"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2025A1515010835"],"award-info":[{"award-number":["2025A1515010835"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2023A1515011967"],"award-info":[{"award-number":["2023A1515011967"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Biotechnol Lett"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1007\/s10529-026-03779-5","type":"journal-article","created":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T10:02:19Z","timestamp":1788775339000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The impact of DNA methyltransferase inhibitors on carotenoid metabolism in Dunaliella salina"],"prefix":"10.1007","volume":"48","author":[{"given":"Yue-Li","family":"Yuan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jv-Liang","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Hua","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian-Guo","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,7]]},"reference":[{"key":"3779_CR2","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1111\/jpy.12819","volume":"55","author":"R Bacova","year":"2019","unstructured":"Bacova R, Klejdus B, Ryant P et al (2019) The effects of 5-azacytidine and cadmium on global 5-methylcytosine content and secondary metabolites in the freshwater microalgae Chlamydomonas reinhardtii and Scenedesmus quadricauda. J Phycol 55:329\u2013342. https:\/\/doi.org\/10.1111\/jpy.12819","journal-title":"J Phycol"},{"key":"3779_CR3","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.04361-22","author":"H Chen","year":"2023","unstructured":"Chen H, Liang M, Ye Z et al (2023) Engineering the \u03b2-carotene metabolic pathway of microalgae Dunaliella to confirm its carotenoid synthesis pattern in comparison to bacteria and plants. Microbiol Spectr. https:\/\/doi.org\/10.1128\/spectrum.04361-22","journal-title":"Microbiol Spectr"},{"key":"3779_CR5","doi-asserted-by":"publisher","DOI":"10.1016\/j.algal.2024.103739","volume":"84","author":"J Dai","year":"2024","unstructured":"Dai J, Chen H, Liang M, Jiang J (2024) Revealing the effects of two DNA methyltransferase inhibitors on DNA methylation and carotenoid metabolism in Chlamydomonas reinhardtii by comparative transcriptome and physiological analysis. Algal Res 84:103739. https:\/\/doi.org\/10.1016\/j.algal.2024.103739","journal-title":"Algal Res"},{"key":"3779_CR6","doi-asserted-by":"publisher","first-page":"12074","DOI":"10.1021\/acs.jafc.2c03006","volume":"70","author":"J Dai","year":"2022","unstructured":"Dai J, Song D, Chen H et al (2022) Effects of piperonyl butoxide on the accumulation of lipid and the transcript levels of DtMFP\u03b1 in Dunaliella tertiolecta. J Agric Food Chem 70:12074\u201312084. https:\/\/doi.org\/10.1021\/acs.jafc.2c03006","journal-title":"J Agric Food Chem"},{"key":"3779_CR7","doi-asserted-by":"publisher","first-page":"E2183","DOI":"10.1073\/pnas.1209329109","volume":"109","author":"RH Dowen","year":"2012","unstructured":"Dowen RH, Pelizzola M, Schmitz RJ et al (2012) Widespread dynamic dna methylation in response to biotic stress. Proc Natl Acad Sci 109:E2183\u2013E2191. https:\/\/doi.org\/10.1073\/pnas.1209329109","journal-title":"Proc Natl Acad Sci"},{"key":"3779_CR8","doi-asserted-by":"publisher","DOI":"10.1016\/j.algal.2020.102002","volume":"50","author":"PJ Harvey","year":"2020","unstructured":"Harvey PJ, Ben-Amotz A (2020) Towards a sustainable Dunaliella salina microalgal biorefinery for 9-cis \u03b2-carotene production. Algal Res 50:102002. https:\/\/doi.org\/10.1016\/j.algal.2020.102002","journal-title":"Algal Res"},{"key":"3779_CR9","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1146\/annurev-arplant-042110-103806","volume":"62","author":"G He","year":"2011","unstructured":"He G, Elling AA, Deng XW (2011) The epigenome and plant development. Annu Rev Plant Biol 62:411\u2013435. https:\/\/doi.org\/10.1146\/annurev-arplant-042110-103806","journal-title":"Annu Rev Plant Biol"},{"key":"3779_CR10","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-28940-2","author":"L He","year":"2022","unstructured":"He L, Huang H, Bradai M et al (2022) DNA methylation-free arabidopsis reveals crucial roles of DNA methylation in regulating gene expression and development. Nat Commun. https:\/\/doi.org\/10.1038\/s41467-022-28940-2","journal-title":"Nat Commun"},{"key":"3779_CR11","doi-asserted-by":"publisher","first-page":"1430","DOI":"10.1073\/pnas.1815441116","volume":"116","author":"H Huang","year":"2019","unstructured":"Huang H, Liu R, Niu Q et al (2019) Global increase in DNA methylation during orange fruit development and ripening. Proc Natl Acad Sci USA 116:1430\u20131436. https:\/\/doi.org\/10.1073\/pnas.1815441116","journal-title":"Proc Natl Acad Sci USA"},{"key":"3779_CR12","doi-asserted-by":"publisher","first-page":"3541","DOI":"10.1021\/acs.jafc.1c06391","volume":"70","author":"H Jia","year":"2022","unstructured":"Jia H, Jia H, Lu S et al (2022) DNA and histone methylation regulates different types of fruit ripening by transcriptome and proteome analyses. J Agric Food Chem 70:3541\u20133556. https:\/\/doi.org\/10.1021\/acs.jafc.1c06391","journal-title":"J Agric Food Chem"},{"key":"3779_CR14","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2021.596236","author":"S Kumar","year":"2021","unstructured":"Kumar S, Mohapatra T (2021) Dynamics of DNA methylation and its functions in plant growth and development. Front Plant Sci. https:\/\/doi.org\/10.3389\/fpls.2021.596236","journal-title":"Front Plant Sci"},{"key":"3779_CR15","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1016\/j.tibtech.2008.07.002","volume":"26","author":"PP Lamers","year":"2008","unstructured":"Lamers PP, Janssen M, De Vos RCH et al (2008) Exploring and exploiting carotenoid accumulation in Dunaliella salina for cell-factory applications. Trends Biotechnol 26:631\u2013638. https:\/\/doi.org\/10.1016\/j.tibtech.2008.07.002","journal-title":"Trends Biotechnol"},{"key":"3779_CR16","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-60848-3","author":"C Li","year":"2024","unstructured":"Li C, Wang C, Cheng Z et al (2024) Carotenoid biosynthesis genes LcLCYB, LcLCYE, and LcBCH from wolfberry confer increased carotenoid content and improved salt tolerance in tobacco. Sci Rep-UK. https:\/\/doi.org\/10.1038\/s41598-024-60848-3","journal-title":"Sci Rep-UK"},{"key":"3779_CR17","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2021.129562","author":"Z Li","year":"2021","unstructured":"Li Z, Hu Y, Chang M et al (2021) 5-Azacytidine pre-treatment alters DNA methylation levels and induces genes responsive to salt stress in kenaf (Hibiscus cannabinus L.). Chemosphere. https:\/\/doi.org\/10.1016\/j.chemosphere.2021.129562","journal-title":"Chemosphere"},{"key":"3779_CR19","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.00069-23","volume":"11","author":"M Liang","year":"2023","unstructured":"Liang M, Xie S, Dai J et al (2023) Roles of two phytoene synthases and orange protein in carotenoid metabolism of the beta-carotene-accumulating Dunaliella salina. Microbiol Spectr 11:e6923. https:\/\/doi.org\/10.1128\/spectrum.00069-23","journal-title":"Microbiol Spectr"},{"key":"3779_CR20","doi-asserted-by":"publisher","first-page":"e2614","DOI":"10.1128\/AEM.02614-18","volume":"85","author":"M Liang","year":"2019","unstructured":"Liang M, Xue L, Jiang J (2019) Two-stage cultivation of Dunaliella tertiolecta with glycerol and triethylamine for lipid accumulation: a viable way to alleviate the inhibitory effect of triethylamine on biomass. Appl Environ Microb 85:e2614\u2013e2618. https:\/\/doi.org\/10.1128\/AEM.02614-18","journal-title":"Appl Environ Microb"},{"key":"3779_CR21","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1016\/0076-6879(87)48036-1","volume":"148","author":"H Lichtenthaler","year":"1987","unstructured":"Lichtenthaler H (1987) Chlorophylls and carotenoids: pigments of photosynthetic biomembranes. Methods Enzymol 148:350\u2013382","journal-title":"Methods Enzymol"},{"key":"3779_CR22","doi-asserted-by":"publisher","first-page":"1788","DOI":"10.1105\/tpc.114.135467","volume":"27","author":"C Liu","year":"2015","unstructured":"Liu C, Finke A, D\u00edaz M et al (2015) Repair of DNA damage induced by the cytidine analog zebularine requires ATR and ATM in Arabidopsis. Plant Cell 27:1788\u20131800. https:\/\/doi.org\/10.1105\/tpc.114.135467","journal-title":"Plant Cell"},{"key":"3779_CR23","doi-asserted-by":"publisher","first-page":"964","DOI":"10.1038\/ng.3859","volume":"49","author":"SJ Mondo","year":"2017","unstructured":"Mondo SJ, Dannebaum RO, Kuo RC et al (2017) Widespread adenine N6-methylation of active genes in fungi. Nat Genet 49:964\u2013968. https:\/\/doi.org\/10.1038\/ng.3859","journal-title":"Nat Genet"},{"key":"3779_CR24","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1016\/j.pbi.2013.03.011","volume":"16","author":"KK Niyogi","year":"2013","unstructured":"Niyogi KK, Truong TB (2013) Evolution of flexible non-photochemical quenching mechanisms that regulate light harvesting in oxygenic photosynthesis. Curr Opin Plant Biol 16:307\u2013314. https:\/\/doi.org\/10.1016\/j.pbi.2013.03.011","journal-title":"Curr Opin Plant Biol"},{"key":"3779_CR25","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2023.1304327","author":"A Pagano","year":"2024","unstructured":"Pagano A, Gomes C, Timmerman E et al (2024) Revealing the transitory and local effect of zebularine on development and on proteome dynamics of Salix purpurea. Front Plant Sci. https:\/\/doi.org\/10.3389\/fpls.2023.1304327","journal-title":"Front Plant Sci"},{"key":"3779_CR26","doi-asserted-by":"publisher","first-page":"1037","DOI":"10.1016\/j.pnsc.2008.10.014","volume":"19","author":"H Peng","year":"2009","unstructured":"Peng H, Zhang J (2009) Plant genomic DNA methylation in response to stresses: potential applications and challenges in plant breeding. Prog Nat Sci 19:1037\u20131045","journal-title":"Prog Nat Sci"},{"key":"3779_CR27","doi-asserted-by":"publisher","first-page":"2780","DOI":"10.1111\/pce.14843","volume":"47","author":"Z Plskova","year":"2024","unstructured":"Plskova Z, Van Breusegem F, Kerchev P (2024) Redox regulation of chromatin remodelling in plants. Plant Cell Environ 47:2780\u20132792. https:\/\/doi.org\/10.1111\/pce.14843","journal-title":"Plant Cell Environ"},{"key":"3779_CR28","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1093\/nar\/gkab1218","volume":"50","author":"K Prochazkova","year":"2022","unstructured":"Prochazkova K, Finke A, Tomastikova ED et al (2022) Zebularine induces enzymatic DNA-protein crosslinks in 45s rDNA heterochromatin of Arabidopsis nuclei. Nucleic Acids Res 50:244\u2013258. https:\/\/doi.org\/10.1093\/nar\/gkab1218","journal-title":"Nucleic Acids Res"},{"key":"3779_CR29","doi-asserted-by":"publisher","first-page":"1445","DOI":"10.1126\/science.1219416","volume":"336","author":"W Qian","year":"2012","unstructured":"Qian W, Miki D, Zhang H et al (2012) A histone acetyltransferase regulates active DNA demethylation in Arabidopsis. Science 336:1445\u20131448. https:\/\/doi.org\/10.1126\/science.1219416","journal-title":"Science"},{"key":"3779_CR30","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1146\/annurev-genet-120215-035254","volume":"50","author":"L Quadrana","year":"2016","unstructured":"Quadrana L, Colot V (2016) Plant transgenerational epigenetics. Annu Rev Genet 50:467\u2013491. https:\/\/doi.org\/10.1146\/annurev-genet-120215-035254","journal-title":"Annu Rev Genet"},{"key":"3779_CR31","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1146\/annurev-nutr-082018-124555","volume":"39","author":"L Sauer","year":"2019","unstructured":"Sauer L, Li B, Bernstein PS (2019) Ocular carotenoid status in health and disease. Annu Rev Nutr 39:95\u2013120. https:\/\/doi.org\/10.1146\/annurev-nutr-082018-124555","journal-title":"Annu Rev Nutr"},{"key":"3779_CR32","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1016\/j.cell.2012.10.054","volume":"152","author":"H Stroud","year":"2013","unstructured":"Stroud H, Greenberg MVC, Feng S et al (2013) Comprehensive analysis of silencing mutants reveals complex regulation of the Arabidopsis methylome. Cell 152:352\u2013364. https:\/\/doi.org\/10.1016\/j.cell.2012.10.054","journal-title":"Cell"},{"key":"3779_CR33","doi-asserted-by":"publisher","DOI":"10.1016\/j.plantsci.2019.110331","volume":"290","author":"T Sun","year":"2020","unstructured":"Sun T, Li L (2020) Toward the \u2018golden\u2019 era: the status in uncovering the regulatory control of carotenoid accumulation in plants. Plant Sci 290:110331. https:\/\/doi.org\/10.1016\/j.plantsci.2019.110331","journal-title":"Plant Sci"},{"key":"3779_CR34","doi-asserted-by":"publisher","DOI":"10.1186\/s43897-022-00023-2","author":"T Sun","year":"2022","unstructured":"Sun T, Rao S, Zhou X, Li L (2022) Plant carotenoids: recent advances and future perspectives. Mol Hortic. https:\/\/doi.org\/10.1186\/s43897-022-00023-2","journal-title":"Mol Hortic"},{"key":"3779_CR35","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-024-03543-4","volume":"22","author":"AM Valdes","year":"2024","unstructured":"Valdes AM, Louca P, Visconti A et al (2024) Vitamin A carotenoids, but not retinoids, mediate the impact of a healthy diet on gut microbial diversity. BMC Med 22:321. https:\/\/doi.org\/10.1186\/s12916-024-03543-4","journal-title":"BMC Med"},{"key":"3779_CR36","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1007\/s00497-021-00422-3","volume":"34","author":"J Vigneau","year":"2021","unstructured":"Vigneau J, Borg M (2021) The epigenetic origin of life history transitions in plants and algae. Plant Reprod 34:267\u2013285. https:\/\/doi.org\/10.1007\/s00497-021-00422-3","journal-title":"Plant Reprod"},{"key":"3779_CR37","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-02219-3","volume":"8","author":"BP Williams","year":"2017","unstructured":"Williams BP, Gehring M (2017) Stable transgenerational epigenetic inheritance requires a DNA methylation-sensing circuit. Nat Commun 8:2124. https:\/\/doi.org\/10.1038\/s41467-017-02219-3","journal-title":"Nat Commun"},{"key":"3779_CR38","doi-asserted-by":"publisher","first-page":"18","DOI":"10.3390\/md23010018","volume":"23","author":"S Xiang","year":"2025","unstructured":"Xiang S, Qiu X, Yan X et al (2025) Salicylic acid improved the growth of Dunaliella salina and increased the proportion of 9-cis-\u03b2-carotene isomers. Mar Drugs 23:18. https:\/\/doi.org\/10.3390\/md23010018","journal-title":"Mar Drugs"},{"key":"3779_CR39","doi-asserted-by":"publisher","first-page":"148","DOI":"10.3390\/antiox8050148","volume":"8","author":"Y Xu","year":"2019","unstructured":"Xu Y, Harvey PJ (2019) Red light control of \u03b2-carotene isomerisation to 9-cis \u03b2-carotene and carotenoid accumulation in Dunaliella salina. Antioxidants-Basel 8:148. https:\/\/doi.org\/10.3390\/antiox8050148","journal-title":"Antioxidants-Basel"},{"key":"3779_CR40","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1016\/j.ccr.2014.07.028","volume":"26","author":"X Yang","year":"2014","unstructured":"Yang X, Han H, De Carvalho DD et al (2014) Gene body methylation can alter gene expression and is a therapeutic target in cancer. Cancer Cell 26:577\u2013590. https:\/\/doi.org\/10.1016\/j.ccr.2014.07.028","journal-title":"Cancer Cell"},{"key":"3779_CR41","doi-asserted-by":"publisher","DOI":"10.1016\/j.plaphy.2023.108075","volume":"203","author":"Y Yao","year":"2023","unstructured":"Yao Y, Yang Y, Pan Y et al (2023) Crucial roles of trehalose and 5-azacytidine in alleviating salt stress in tomato: both synergistically and independently. Plant Physiol Bioch 203:108075. https:\/\/doi.org\/10.1016\/j.plaphy.2023.108075","journal-title":"Plant Physiol Bioch"},{"key":"3779_CR42","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1016\/j.hpj.2022.11.003","volume":"9","author":"H Yu","year":"2023","unstructured":"Yu H, Cui N, Guo K et al (2023) Epigenetic changes in the regulation of carotenoid metabolism during honeysuckle flower development. Hortic Plant J 9:577\u2013588. https:\/\/doi.org\/10.1016\/j.hpj.2022.11.003","journal-title":"Hortic Plant J"},{"key":"3779_CR43","doi-asserted-by":"publisher","first-page":"953","DOI":"10.1007\/s00217-007-0789-3","volume":"227","author":"Y Zhu","year":"2008","unstructured":"Zhu Y, Jiang J (2008) Continuous cultivation of Dunaliella salina in photobioreactor for the production of \u03b2-carotene. Eur Food Res Technol 227:953\u2013959. https:\/\/doi.org\/10.1007\/s00217-007-0789-3","journal-title":"Eur Food Res Technol"}],"container-title":["Biotechnology Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10529-026-03779-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10529-026-03779-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10529-026-03779-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T10:02:20Z","timestamp":1788775340000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10529-026-03779-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,7]]},"references-count":39,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["3779"],"URL":"https:\/\/doi.org\/10.1007\/s10529-026-03779-5","relation":{},"ISSN":["0141-5492","1573-6776"],"issn-type":[{"value":"0141-5492","type":"print"},{"value":"1573-6776","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,7]]},"assertion":[{"value":"22 December 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 August 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 August 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 September 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study does not contain any experiments involving humans or animals.","order":2,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","label":"Consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All authors have read the final version and give consent for the article to be published in Biotechnology Letters.","order":4,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"112"}}