{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T17:12:07Z","timestamp":1794244327526,"version":"4.9.0"},"reference-count":83,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2010,6,3]],"date-time":"2010-06-03T00:00:00Z","timestamp":1275523200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biometals"],"published-print":{"date-parts":[[2010,10]]},"DOI":"10.1007\/s10534-010-9343-z","type":"journal-article","created":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T22:46:20Z","timestamp":1275432380000},"page":"769-782","source":"Crossref","is-referenced-by-count":386,"title":["Cadmium exposure in the population: from health risks to strategies of prevention"],"prefix":"10.1007","volume":"23","author":[{"given":"Tim S.","family":"Nawrot","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan A.","family":"Staessen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harry A.","family":"Roels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elke","family":"Munters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann","family":"Cuypers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"Richart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann","family":"Ruttens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Smeets","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herman","family":"Clijsters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaco","family":"Vangronsveld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,6,3]]},"reference":[{"key":"9343_CR1","doi-asserted-by":"crossref","first-page":"284","DOI":"10.2105\/AJPH.92.2.284","volume":"92","author":"A \u00c5kesson","year":"2002","unstructured":"\u00c5kesson A, Berglund M, Schutz A, Bjellerup P, Bremme K, Vahter M (2002) Cadmium exposure in pregnancy and lactation in relation to iron status. Am J Public Health 92:284\u2013287","journal-title":"Am J Public Health"},{"key":"9343_CR2","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1289\/ehp.8033","volume":"113","author":"A \u00c5kesson","year":"2005","unstructured":"\u00c5kesson A, Lundh T, Vahter M, Bjellerup P, Lidfeldt J, Nerbrand C, Samsioe G, Stromberg U, Skerfving S (2005) Tubular and glomerular kidney effects in Swedish women with low environmental cadmium exposure. Environ Health Perspect 113:1627\u20131631","journal-title":"Environ Health Perspect"},{"key":"9343_CR3","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1289\/ehp.8763","volume":"114","author":"A \u00c5kesson","year":"2006","unstructured":"\u00c5kesson A, Bjellerup P, Lundh T, Lidfeldt J, Nerbrand C, Samsioe G, Skerfving S, Vahter M (2006) Cadmium-induced effects on bone in a population-based study of women. Environ Health Perspect 114:830\u2013834","journal-title":"Environ Health Perspect"},{"key":"9343_CR4","doi-asserted-by":"crossref","first-page":"6435","DOI":"10.1158\/0008-5472.CAN-08-0329","volume":"68","author":"A \u00c5kesson","year":"2008","unstructured":"\u00c5kesson A, Julin B, Wolk A (2008) Long-term dietary cadmium intake and postmenopausal endometrial cancer incidence: a population-based prospective cohort study. Cancer Res 68:6435\u20136441","journal-title":"Cancer Res"},{"key":"9343_CR5","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1097\/MCP.0b013e328013f47e","volume":"13","author":"E Alfaro-Moreno","year":"2007","unstructured":"Alfaro-Moreno E, Nawrot TS, Nemmar A, Nemery B (2007) Particulate matter in the environment: pulmonary and cardiovascular effects. Curr Opin Pulm Med 13:98\u2013106","journal-title":"Curr Opin Pulm Med"},{"key":"9343_CR6","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1359\/jbmr.2000.15.8.1579","volume":"15","author":"T Alfv\u00e9n","year":"2000","unstructured":"Alfv\u00e9n T, Elinder CG, Carlsson MD, Grubb A, Hellstrom L, Persson B, Pettersson C, Spang G, Schutz A, J\u00e4rup L (2000) Low-level cadmium exposure and osteoporosis. J Bone Miner Res 15:1579\u20131586","journal-title":"J Bone Miner Res"},{"key":"9343_CR7","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1359\/JBMR.040202","volume":"19","author":"T Alfv\u00e9n","year":"2004","unstructured":"Alfv\u00e9n T, Elinder CG, Hellstrom L, Lagarde F, J\u00e4rup L (2004) Cadmium exposure and distal forearm fractures. J Bone Miner Res 19:900\u2013905","journal-title":"J Bone Miner Res"},{"key":"9343_CR8","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.toxlet.2007.07.007","volume":"173","author":"K Arisawa","year":"2007","unstructured":"Arisawa K, Uemura H, Hiyoshi M, Dakeshita S, Kitayama A, Saito H, Soda M (2007) Cause-specific mortality and cancer incidence rates in relation to urinary beta2-microglobulin: 23-year follow-up study in a cadmium-polluted area. Toxicol Lett 173:168\u2013174","journal-title":"Toxicol Lett"},{"key":"9343_CR9","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.envres.2009.04.012","volume":"109","author":"CL Banza","year":"2009","unstructured":"Banza CL, Nawrot TS, Haufroid V, Decree S, De PT, Smolders E, Kabyla BI, Luboya ON, Ilunga AN, Mutombo AM, Nemery B (2009) High human exposure to cobalt and other metals in Katanga, a mining area of the Democratic Republic of Congo. Environ Res 109:745\u2013752","journal-title":"Environ Res"},{"key":"9343_CR10","doi-asserted-by":"crossref","first-page":"248","DOI":"10.2119\/molmed.2008.00104","volume":"15","author":"S Benoff","year":"2009","unstructured":"Benoff S, Hauser R, Marmar JL, Hurley IR, Napolitano B, Centola GM (2009) Cadmium concentrations in blood and seminal plasma: correlations with sperm number and motility in three male populations (infertility patients, artificial insemination donors, and unselected volunteers). Mol Med 15:248\u2013262","journal-title":"Mol Med"},{"key":"9343_CR11","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1289\/ehp.941021058","volume":"102","author":"M Berglund","year":"1994","unstructured":"Berglund M, \u00c5kesson A, Nermell B, Vahter M (1994) Intestinal absorption of dietary cadmium in women depends on body iron stores and fiber intake. Environ Health Perspect 102:1058\u20131066","journal-title":"Environ Health Perspect"},{"key":"9343_CR12","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1038\/sj.jes.7500590","volume":"18","author":"G Bolte","year":"2008","unstructured":"Bolte G, Heitmann D, Kiranoglu M, Schierl R, Diemer J, Koerner W, Fromme H (2008) Exposure to environmental tobacco smoke in German restaurants, pubs and discotheques. J Expo Sci Environ Epidemiol 18:262\u2013271","journal-title":"J Expo Sci Environ Epidemiol"},{"key":"9343_CR13","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/0140-6736(90)92201-R","volume":"336","author":"JP Buchet","year":"1990","unstructured":"Buchet JP, Lauwerys R, Roels H, Bernard A, Bruaux P, Claeys F, Ducoffre G, de PP, Staessen J, Amery A (1990) Renal effects of cadmium body burden of the general population. Lancet 336:699\u2013702","journal-title":"Lancet"},{"key":"9343_CR14","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.taap.2009.03.025","volume":"238","author":"C Byrne","year":"2009","unstructured":"Byrne C, Divekar SD, Storchan GB, Parodi DA, Martin MB (2009) Cadmium\u2014a metallohormone? Toxicol Appl Pharmacol 238:266\u2013271","journal-title":"Toxicol Appl Pharmacol"},{"key":"9343_CR15","unstructured":"Centers for Disease Control and Prevention (CDC) (2005) Third national report on human exposure to environmental chemicals. NCEH 05-0570, Atlanta, GA, 21 August 2008, pp 1\u2013467. http:\/\/www.cdc.gov\/exposurereport\/pdf\/thirdreport.pdf . Accessed November 2010"},{"key":"9343_CR16","first-page":"1","volume":"980","author":"CONTAM","year":"2009","unstructured":"CONTAM (2009) Scientific opinion of the panel on contaminants in the food chain on a request from the European commission on cadmium in food. EFSA J 980:1\u2013139","journal-title":"EFSA J"},{"key":"9343_CR17","doi-asserted-by":"crossref","unstructured":"Cuypers A, Plusquin M, Remans T, Jozefczak M, Keunen E, Gielen H, Opdenakker K, Nair AR, Munters E, Artois TJ, Nawrot T, Vangronsveld J, Smeets K (2010) Cadmium stress: an oxidative challenge. Biometals. doi: 10.1007\/s10534-010-9329-x","DOI":"10.1007\/s10534-010-9329-x"},{"key":"9343_CR18","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.envres.2008.10.008","volume":"109","author":"A Engstrom","year":"2009","unstructured":"Engstrom A, Skerving S, Lidfeldt J, Burgaz A, Lundh T, Samsioe G, Vahter M, \u00c5kesson A (2009) Cadmium-induced bone effect is not mediated via low serum 1, 25-dihydroxy vitamin D. Environ Res 109:188\u2013192","journal-title":"Environ Res"},{"key":"9343_CR19","unstructured":"European Community Report (EUR 23424 EN) http:\/\/ecb.jrc.ec.europa.eu\/Documents\/Existing-Chemicals\/RISK_ASSESSMENT\/SUMMARY\/cdmetal_cdoxidesum303.pdf . Assessed February 2010"},{"key":"9343_CR20","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1007\/s00420-002-0390-9","volume":"76","author":"T Ezaki","year":"2003","unstructured":"Ezaki T, Tsukahara T, Moriguchi J, Furuki K, Fukui Y, Ukai H, Okamoto S, Sakurai H, Honda S, Ikeda M (2003) Analysis for threshold levels of cadmium in urine that induce tubular dysfunction among women in non-polluted areas in Japan. Int Arch Occup Environ Health 76:197\u2013204","journal-title":"Int Arch Occup Environ Health"},{"key":"9343_CR81","doi-asserted-by":"crossref","unstructured":"Flanagan PR, McLellan JS, Haist J, Cherian G, Chamberlain MJ, Valberg LS (1978) Increased dietary cadmium absorption in mice and human subjects with iron deficiency. Gastroenterology 74:841\u2013846","DOI":"10.1016\/0016-5085(78)90138-5"},{"key":"9343_CR21","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1289\/ehp.11452","volume":"116","author":"CM Gallagher","year":"2008","unstructured":"Gallagher CM, Kovach JS, Meliker JR (2008) Urinary cadmium and osteoporosis in U.S. Women \u2265 50\u00a0years of age: NHANES 1988\u20131994 and 1999\u20132004. Environ Health Perspect 116:1338\u20131343","journal-title":"Environ Health Perspect"},{"key":"9343_CR22","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1093\/oxfordjournals.aje.a116227","volume":"135","author":"JP Gennart","year":"1992","unstructured":"Gennart JP, Buchet JP, Roels H, Ghyselen P, Ceulemans E, Lauwerys R (1992) Fertility of male workers exposed to cadmium, lead, or manganese. Am J Epidemiol 135:1208\u20131219","journal-title":"Am J Epidemiol"},{"key":"9343_CR23","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1080\/07315724.2008.10719709","volume":"27","author":"MA Grondin","year":"2008","unstructured":"Grondin MA, Ruivard M, Perreve A, Derumeaux-Burel H, Perthus I, Roblin J, Thiollieres F, Gerbaud L (2008) Prevalence of iron deficiency and health-related quality of life among female students. J Am Coll Nutr 27:337\u2013341","journal-title":"J Am Coll Nutr"},{"key":"9343_CR82","doi-asserted-by":"crossref","unstructured":"Hartwig A (2010) Mechanisms in cadmium-induced carcinogenicity: recent insights. Biometals. doi: 10.1007\/s10534-010-9330-4","DOI":"10.1007\/s10534-010-9330-4"},{"key":"9343_CR24","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.envres.2007.10.004","volume":"106","author":"M Haswell-Elkins","year":"2008","unstructured":"Haswell-Elkins M, Satarug S, O\u2019Rourke P, Moore M, Ng J, McGrath V, Walmby M (2008) Striking association between urinary cadmium level and albuminuria among Torres Strait Islander people with diabetes. Environ Res 106:379\u2013383","journal-title":"Environ Res"},{"key":"9343_CR25","first-page":"295","volume":"58","author":"AB Hill","year":"1965","unstructured":"Hill AB (1965) The environment and disease: association or causation? Proc R Soc Med 58:295\u2013300","journal-title":"Proc R Soc Med"},{"key":"9343_CR26","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.envres.2006.05.009","volume":"103","author":"J Hogervorst","year":"2007","unstructured":"Hogervorst J, Plusquin M, Vangronsveld J, Nawrot T, Cuypers A, Van HE, Roels HA, Carleer R, Staessen JA (2007) House dust as possible route of environmental exposure to cadmium and lead in the adult general population. Environ Res 103:30\u201337","journal-title":"Environ Res"},{"key":"9343_CR27","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0013-9351(02)00035-X","volume":"91","author":"R Honda","year":"2003","unstructured":"Honda R, Tsuritani I, Noborisaka Y, Suzuki H, Ishizaki M, Yamada Y (2003) Urinary cadmium excretion is correlated with calcaneal bone mass in Japanese women living in an urban area. Environ Res 91:63\u201370","journal-title":"Environ Res"},{"key":"9343_CR28","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1023\/B:BIOM.0000045729.68774.a1","volume":"17","author":"L J\u00e4rup","year":"2004","unstructured":"J\u00e4rup L, Alfv\u00e9n T (2004) Low level cadmium exposure, renal and bone effects\u2014the OSCAR study. Biometals 17:505\u2013509","journal-title":"Biometals"},{"key":"9343_CR29","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1136\/oem.55.7.435","volume":"55","author":"L J\u00e4rup","year":"1998","unstructured":"J\u00e4rup L, Alfv\u00e9n T, Persson B, Toss G, Elinder CG (1998a) Cadmium may be a risk factor for osteoporosis. Occup Environ Med 55:435\u2013439","journal-title":"Occup Environ Med"},{"key":"9343_CR30","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1136\/oem.55.11.755","volume":"55","author":"L J\u00e4rup","year":"1998","unstructured":"J\u00e4rup L, Bellander T, Hogstedt C, Spang G (1998b) Mortality and cancer incidence in Swedish battery workers exposed to cadmium and nickel. Occup Environ Med 55:755\u2013759","journal-title":"Occup Environ Med"},{"issue":"Suppl 1","key":"9343_CR31","first-page":"1","volume":"24","author":"L J\u00e4rup","year":"1998","unstructured":"J\u00e4rup L, Berglund M, Elinder CG, Nordberg G, Vahter M (1998c) Health effects of cadmium exposure\u2014a review of the literature and a risk estimate. Scand J Work Environ Health 24(Suppl 1):1\u201351","journal-title":"Scand J Work Environ Health"},{"key":"9343_CR32","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0048-9697(85)90034-8","volume":"43","author":"Z Jaworowski","year":"1985","unstructured":"Jaworowski Z, Barbalat F, Blain C, Peyre E (1985) Heavy metals in human and animal bones from ancient and contemporary France. Sci Total Environ 43:103\u2013126","journal-title":"Sci Total Environ"},{"key":"9343_CR33","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1038\/ng1172","volume":"34","author":"YH Jin","year":"2003","unstructured":"Jin YH, Clark AB, Slebos RJ, Al-Refai H, Taylor JA, Kunkel TA, Resnick MA, Gordenin DA (2003) Cadmium is a mutagen that acts by inhibiting mismatch repair. Nat Genet 34:326\u2013329","journal-title":"Nat Genet"},{"key":"9343_CR34","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.envres.2004.02.012","volume":"96","author":"T Jin","year":"2004","unstructured":"Jin T, Nordberg G, Ye T, Bo M, Wang H, Zhu G, Kong Q, Bernard A (2004) Osteoporosis and renal dysfunction in a general population exposed to cadmium in China. Environ Res 96:353\u2013359","journal-title":"Environ Res"},{"key":"9343_CR35","unstructured":"Kazantzis G, Blanks RG, Sullivan KR (1992) Is cadmium a human carcinogen? IARC Sci Publ 118:435\u2013446"},{"key":"9343_CR36","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.cdp.2006.12.001","volume":"31","author":"E Kellen","year":"2007","unstructured":"Kellen E, Zeegers MP, Hond ED, Buntinx F (2007) Blood cadmium may be associated with bladder carcinogenesis: the Belgian case\u2013control study on bladder cancer. Cancer Detect Prev 31:77\u201382","journal-title":"Cancer Detect Prev"},{"key":"9343_CR37","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1016\/j.envres.2009.07.006","volume":"109","author":"M Kippler","year":"2009","unstructured":"Kippler M, Goessler W, Nermell B, Ekstrom EC, Lonnerdal B, El AS, Vahter M (2009) Factors influencing intestinal cadmium uptake in pregnant Bangladeshi women\u2014a prospective cohort study. Environ Res 109:914\u2013921","journal-title":"Environ Res"},{"key":"9343_CR83","doi-asserted-by":"crossref","unstructured":"Kobayashi E, Suwazono Y, Honda R, Dochi M, Nishijo M, Kido T, Nakagawa H (2008) Changes in renal tubular and glomerular functions and biological acid-base balance after soil replacement in Cd-polluted rice paddies calculated with a general linear mixed model. Biol Trace Elem Res 124:164\u2013172","DOI":"10.1007\/s12011-008-8125-8"},{"key":"9343_CR38","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1289\/ehp.8035","volume":"114","author":"AM Kriegel","year":"2006","unstructured":"Kriegel AM, Soliman AS, Zhang Q, El-Ghawalby N, Ezzat F, Soultan A, bdel-Wahab M, Fathy O, Ebidi G, Bassiouni N, Hamilton SR, Abbruzzese JL, Lacey MR, Blake DA (2006) Serum cadmium levels in pancreatic cancer patients from the East Nile Delta region of Egypt. Environ Health Perspect 114:113\u2013119","journal-title":"Environ Health Perspect"},{"key":"9343_CR39","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1080\/00039890409602957","volume":"59","author":"I Kurihara","year":"2004","unstructured":"Kurihara I, Kobayashi E, Suwazono Y, Uetani M, Inaba T, Oishiz M, Kido T, Nakagawa H, Nogawa K (2004) Association between exposure to cadmium and blood pressure in Japanese peoples. Arch Environ Health 59:711\u2013716","journal-title":"Arch Environ Health"},{"key":"9343_CR40","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1093\/jnci\/djj233","volume":"98","author":"JA McElroy","year":"2006","unstructured":"McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA (2006) Cadmium exposure and breast cancer risk. J Natl Cancer Inst 98:869\u2013873","journal-title":"J Natl Cancer Inst"},{"key":"9343_CR41","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1289\/ehp.11236","volume":"117","author":"A Menke","year":"2009","unstructured":"Menke A, Muntner P, Silbergeld EK, Platz EA, Guallar E (2009) Cadmium levels in urine and mortality among U.S. adults. Environ Health Perspect 117:190\u2013196","journal-title":"Environ Health Perspect"},{"key":"9343_CR42","doi-asserted-by":"crossref","unstructured":"Messner B, Bernhard D (2010) Cadmium and cardiovascular diseases: cell biology, pathophysiology, and epidemiological relevance. Biometals. doi: 10.1007\/s10534-010-9314-4","DOI":"10.1007\/s10534-010-9314-4"},{"key":"9343_CR43","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1161\/ATVBAHA.109.190082","volume":"29","author":"B Messner","year":"2009","unstructured":"Messner B, Knoflach M, Seubert A, Ritsch A, Pfaller K, Henderson B, Shen YH, Zeller I, Willeit J, Laufer G, Wick G, Kiechl S, Bernhard D (2009) Cadmium is a novel and independent risk factor for early atherosclerosis mechanisms and in vivo relevance. Arterioscler Thromb Vasc Biol 29:1392\u20131398","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"9343_CR44","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/00043798-199602000-00003","volume":"3","author":"H Nakagawa","year":"1996","unstructured":"Nakagawa H, Nishijo M (1996) Environmental cadmium exposure, hypertension and cardiovascular risk. J Cardiovasc Risk 3:11\u201317","journal-title":"J Cardiovasc Risk"},{"key":"9343_CR45","doi-asserted-by":"crossref","first-page":"3196","DOI":"10.1161\/01.CIR.0000130848.18636.B2","volume":"109","author":"A Navas-Acien","year":"2004","unstructured":"Navas-Acien A, Selvin E, Sharrett AR, Calderon-Aranda E, Silbergeld E, Guallar E (2004) Lead, cadmium, smoking, and increased risk of peripheral arterial disease. Circulation 109:3196\u20133201","journal-title":"Circulation"},{"key":"9343_CR46","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1289\/ehp.7329","volume":"113","author":"A Navas-Acien","year":"2005","unstructured":"Navas-Acien A, Silbergeld EK, Sharrett R, Calderon-Aranda E, Selvin E, Guallar E (2005) Metals in urine and peripheral arterial disease. Environ Health Perspect 113:164\u2013169","journal-title":"Environ Health Perspect"},{"key":"9343_CR47","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1093\/aje\/kwp248","volume":"170","author":"A Navas-Acien","year":"2009","unstructured":"Navas-Acien A, Tellez-Plaza M, Guallar E, Muntner P, Silbergeld E, Jaar B, Weaver V (2009) Blood cadmium and lead and chronic kidney disease in US adults: a joint analysis. Am J Epidemiol 170:1156\u20131164","journal-title":"Am J Epidemiol"},{"key":"9343_CR48","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1007\/s11906-003-0082-1","volume":"5","author":"T Nawrot","year":"2003","unstructured":"Nawrot T, Den HE, Thijs L, Staessen JA (2003) Isolated systolic hypertension and the risk of vascular disease. Curr Hypertens Rep 5:372\u2013379","journal-title":"Curr Hypertens Rep"},{"key":"9343_CR49","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S1470-2045(06)70545-9","volume":"7","author":"T Nawrot","year":"2006","unstructured":"Nawrot T, Plusquin M, Hogervorst J, Roels HA, Celis H, Thijs L, Vangronsveld J, Van HE, Staessen JA (2006) Environmental exposure to cadmium and risk of cancer: a prospective population-based study. Lancet Oncol 7:119\u2013126","journal-title":"Lancet Oncol"},{"key":"9343_CR50","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1289\/ehp.11667","volume":"116","author":"TS Nawrot","year":"2008","unstructured":"Nawrot TS, Van HE, Thijs L, Richart T, Kuznetsova T, Jin Y, Vangronsveld J, Roels HA, Staessen JA (2008) Cadmium-related mortality and long-term secular trends in the cadmium body burden of an environmentally exposed population. Environ Health Perspect 116:1620\u20131628","journal-title":"Environ Health Perspect"},{"key":"9343_CR51","doi-asserted-by":"crossref","first-page":"4595","DOI":"10.1016\/j.atmosenv.2009.06.010","volume":"43","author":"TS Nawrot","year":"2009","unstructured":"Nawrot TS, Kuenzli N, Sunyer J, Shi TM, Moreno T, Viana M, Heinrich J, Forsberg B, Kelly FJ, Sughis M, Nemery B, Borm P (2009) Oxidative properties of ambient PM2.5 and elemental composition: heterogeneous associations in 19 European cities. Atmos Environ 43:4595\u20134602","journal-title":"Atmos Environ"},{"key":"9343_CR52","doi-asserted-by":"crossref","unstructured":"Nawrot T, Geusens P, Nulens T, Nemery B (2010). Occupational cadmium exposure, calcium excretion, bone density and risk for osteoporosis. J Bone Miner Res 25(6):1441\u20131445","DOI":"10.1002\/jbmr.22"},{"key":"9343_CR53","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.toxlet.2003.09.016","volume":"148","author":"M Nishijo","year":"2004","unstructured":"Nishijo M, Tawara K, Honda R, Kuriwaki J, Nakagawa H, Tanebe K, Saito S (2004) Cadmium and nutritional intake in pregnant Japanese women. Toxicol Lett 148:171\u2013176","journal-title":"Toxicol Lett"},{"key":"9343_CR54","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1136\/oem.2006.026591","volume":"63","author":"M Nishijo","year":"2006","unstructured":"Nishijo M, Morikawa Y, Nakagawa H, Tawara K, Miura K, Kido T, Ikawa A, Kobayashi E, Nogawa K (2006) Causes of death and renal tubular dysfunction in residents exposed to cadmium in the environment. Occup Environ Med 63:545\u2013550","journal-title":"Occup Environ Med"},{"key":"9343_CR55","doi-asserted-by":"crossref","unstructured":"Nordberg GF, Nogawa K, Nordberg M et al (2007) Cadmium. In: Nordberg GF, Fowler BF, Nordberg M et al (eds) Handbook on the toxicology of metals. Elsevier, Amsterdam, pp 445\u2013486","DOI":"10.1016\/B978-012369413-3\/50078-1"},{"key":"9343_CR56","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1289\/ehp.021101185","volume":"110","author":"IM Olsson","year":"2002","unstructured":"Olsson IM, Bensryd I, Lundh T, Ottosson H, Skerfving S, Oskarsson A (2002) Cadmium in blood and urine\u2014impact of sex, age, dietary intake, iron status, and former smoking\u2014association of renal effects. Environ Health Perspect 110:1185\u20131190","journal-title":"Environ Health Perspect"},{"key":"9343_CR57","doi-asserted-by":"crossref","first-page":"A510","DOI":"10.1289\/ehp.113-a510b","volume":"113","author":"M Plusquin","year":"2005","unstructured":"Plusquin M, Nawrot TS, Staessen JA (2005) Peripheral arterial disease and metals in urine and blood. Environ Health Perspect 113:A510\u2013A511","journal-title":"Environ Health Perspect"},{"key":"9343_CR58","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1161\/01.CIR.0000112642.63927.54","volume":"109","author":"HE Resnick","year":"2004","unstructured":"Resnick HE, Lindsay RS, McDermott MM, Devereux RB, Jones KL, Fabsitz RR, Howard BV (2004) Relationship of high and low ankle brachial index to all-cause and cardiovascular disease mortality: the Strong Heart Study. Circulation 109:733\u2013739","journal-title":"Circulation"},{"key":"9343_CR59","doi-asserted-by":"crossref","first-page":"251","DOI":"10.3109\/08860229909085087","volume":"21","author":"HA Roels","year":"1999","unstructured":"Roels HA, Roels HA, Hoet P, Lison D (1999) Usefulness of biomarkers of exposure to inorganic mercury, lead, or cadmium in controlling occupational and environmental risks of nephrotoxicity. Ren Fail 21:251\u2013262","journal-title":"Ren Fail"},{"key":"9343_CR60","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.toxlet.2005.01.004","volume":"157","author":"S Satarug","year":"2005","unstructured":"Satarug S, Nishijo M, Ujjin P, Vanavanitkun Y, Moore MR (2005) Cadmium-induced nephropathy in the development of high blood pressure. Toxicol Lett 157:57\u201368","journal-title":"Toxicol Lett"},{"key":"9343_CR61","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1136\/oem.2007.035576","volume":"65","author":"R Schutte","year":"2008","unstructured":"Schutte R, Nawrot T, Richart T, Thijs L, Roels HA, Van Bortel LM, Struijker-Boudier H, Staessen JA (2008a) Arterial structure and function and environmental exposure to cadmium. Occup Environ Med 65:412\u2013419","journal-title":"Occup Environ Med"},{"key":"9343_CR62","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1289\/ehp.11167","volume":"116","author":"R Schutte","year":"2008","unstructured":"Schutte R, Nawrot TS, Richart T, Thijs L, Vanderschueren D, Kuznetsova T, Van HE, Roels HA, Staessen JA (2008b) Bone resorption and environmental exposure to cadmium in women: a population study. Environ Health Perspect 116:777\u2013783","journal-title":"Environ Health Perspect"},{"key":"9343_CR63","doi-asserted-by":"crossref","first-page":"468","DOI":"10.2337\/diacare.26.2.468","volume":"26","author":"GG Schwartz","year":"2003","unstructured":"Schwartz GG, Il\u2019yasova D, Ivanova A (2003) Urinary cadmium, impaired fasting glucose, and diabetes in the NHANES III. Diabetes Care 26:468\u2013470","journal-title":"Diabetes Care"},{"key":"9343_CR64","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1136\/oem.54.3.194","volume":"54","author":"T Sorahan","year":"1997","unstructured":"Sorahan T, Lancashire RJ (1997) Lung cancer mortality in a cohort of workers employed at a cadmium recovery plant in the United States: an analysis with detailed job histories. Occup Environ Med 54:194\u2013201","journal-title":"Occup Environ Med"},{"key":"9343_CR65","first-page":"293","volume":"40","author":"T Sorahan","year":"1983","unstructured":"Sorahan T, Waterhouse JA (1983) Mortality study of nickel-cadmium battery workers by the method of regression models in life tables. Br J Ind Med 40:293\u2013300","journal-title":"Br J Ind Med"},{"key":"9343_CR66","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1136\/oem.52.12.804","volume":"52","author":"T Sorahan","year":"1995","unstructured":"Sorahan T, Lister A, Gilthorpe MS, Harrington JM (1995) Mortality of copper cadmium alloy workers with special reference to lung cancer and non-malignant diseases of the respiratory system, 1946\u201392. Occup Environ Med 52:804\u2013812","journal-title":"Occup Environ Med"},{"key":"9343_CR67","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1016\/S0140-6736(94)92936-X","volume":"343","author":"JA Staessen","year":"1994","unstructured":"Staessen JA, Lauwerys RR, Ide G, Roels HA, Vyncke G, Amery A (1994) Renal function and historical environmental cadmium pollution from zinc smelters. Lancet 343:1523\u20131527","journal-title":"Lancet"},{"key":"9343_CR68","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1016\/S0140-6736(98)09356-8","volume":"353","author":"JA Staessen","year":"1999","unstructured":"Staessen JA, Roels HA, Emelianov D, Kuznetsova T, Thijs L, Vangronsveld J, Fagard R (1999) Environmental exposure to cadmium, forearm bone density, and risk of fractures: prospective population study. Public Health and Environmental Exposure to Cadmium (PheeCad) Study Group. Lancet 353:1140\u20131144","journal-title":"Lancet"},{"key":"9343_CR69","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/S0895-7061(99)00187-9","volume":"13","author":"JA Staessen","year":"2000","unstructured":"Staessen JA, Kuznetsova T, Roels HA, Emelianov D, Fagard R (2000) Exposure to cadmium and conventional and ambulatory blood pressures in a prospective population study. Public Health and Environmental Exposure to Cadmium Study Group. Am J Hypertens 13:146\u2013156","journal-title":"Am J Hypertens"},{"key":"9343_CR70","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1016\/S0140-6736(00)04822-4","volume":"357","author":"JA Staessen","year":"2001","unstructured":"Staessen JA, Nawrot T, Hond ED, Thijs L, Fagard R, Hoppenbrouwers K, Koppen G, Nelen V, Schoeters G, Vanderschueren D, Van HE, Verschaeve L, Vlietinck R, Roels HA (2001) Renal function, cytogenetic measurements, and sexual development in adolescents in relation to environmental pollutants: a feasibility study of biomarkers. Lancet 357:1660\u20131669","journal-title":"Lancet"},{"key":"9343_CR71","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1289\/ehp.10764","volume":"116","author":"M Tellez-Plaza","year":"2008","unstructured":"Tellez-Plaza M, Navas-Acien A, Crainiceanu CM, Guallar E (2008) Cadmium exposure and hypertension in the 1999\u20132004 National Health and Nutrition Examination Survey (NHANES). Environ Health Perspect 116:51\u201356","journal-title":"Environ Health Perspect"},{"key":"9343_CR72","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.envres.2006.08.003","volume":"104","author":"M Vahter","year":"2007","unstructured":"Vahter M, \u00c5kesson A, Liden C, Ceccatelli S, Berglund M (2007) Gender differences in the disposition and toxicity of metals. Environ Res 104:85\u201395","journal-title":"Environ Res"},{"key":"9343_CR73","doi-asserted-by":"crossref","unstructured":"Van Der Klift M, Pols HA, Geleijnse JM, Van Der Kuip DA, Hofman A, De Laet CE (2002) Bone mineral density and mortality in elderly men and women: the Rotterdam Study. Bone 30:643\u2013648","DOI":"10.1016\/S8756-3282(02)00670-1"},{"key":"9343_CR74","doi-asserted-by":"crossref","unstructured":"van Wijngaarden, Singer EA, Palapattu GS (2008) Prostate-specific antigen levels in relation to cadmium exposure and zinc intake: results from the 2001\u20132002 National Health and Nutrition Examination Survey. Prostate 68:122\u2013128","DOI":"10.1002\/pros.20668"},{"key":"9343_CR75","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1080\/10937400306465","volume":"6","author":"V Verougstraete","year":"2003","unstructured":"Verougstraete V, Lison D, Hotz P (2003) Cadmium, lung and prostate cancer: a systematic review of recent epidemiological data. J Toxicol Environ Health B Crit Rev 6:227\u2013255","journal-title":"J Toxicol Environ Health B Crit Rev"},{"key":"9343_CR76","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.scitotenv.2006.11.005","volume":"373","author":"M Vinceti","year":"2007","unstructured":"Vinceti M, Venturelli M, Sighinolfi C, Trerotoli P, Bonvicini F, Ferrari A, Bianchi G, Serio G, Bergomi M, Vivoli G (2007) Case-control study of toenail cadmium and prostate cancer risk in Italy. Sci Total Environ 373:77\u201381","journal-title":"Sci Total Environ"},{"key":"9343_CR77","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1359\/jbmr.2003.18.3.553","volume":"18","author":"H Wang","year":"2003","unstructured":"Wang H, Zhu G, Shi Y, Weng S, Jin T, Kong Q, Nordberg GF (2003) Influence of environmental cadmium exposure on forearm bone density. J Bone Miner Res 18:553\u2013560","journal-title":"J Bone Miner Res"},{"key":"9343_CR78","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0300-483X(02)00577-2","volume":"184","author":"RD Watkin","year":"2003","unstructured":"Watkin RD, Nawrot T, Potts RJ, Hart BA (2003) Mechanisms regulating the cadmium-mediated suppression of Sp1 transcription factor activity in alveolar epithelial cells. Toxicology 184:157\u2013178","journal-title":"Toxicology"},{"key":"9343_CR79","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1289\/ehp.021101233","volume":"110","author":"LM Yiin","year":"2002","unstructured":"Yiin LM, Rhoads GG, Rich DQ, Zhang J, Bai Z, Adgate JL, Ashley PJ, Lioy PJ (2002) Comparison of techniques to reduce residential lead dust on carpet and upholstery: the New Jersey assessment of cleaning techniques trial. Environ Health Perspect 110:1233\u20131237","journal-title":"Environ Health Perspect"},{"key":"9343_CR80","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1023\/B:BIOM.0000045728.80518.d9","volume":"17","author":"G Zhu","year":"2004","unstructured":"Zhu G, Wang H, Shi Y, Weng S, Jin T, Kong Q, Nordberg GF (2004) Environmental cadmium exposure and forearm bone density. Biometals 17:499\u2013503","journal-title":"Biometals"}],"container-title":["BioMetals"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10534-010-9343-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10534-010-9343-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10534-010-9343-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,5]],"date-time":"2020-06-05T07:55:51Z","timestamp":1591343751000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10534-010-9343-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6,3]]},"references-count":83,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,10]]}},"alternative-id":["9343"],"URL":"https:\/\/doi.org\/10.1007\/s10534-010-9343-z","relation":{},"ISSN":["0966-0844","1572-8773"],"issn-type":[{"value":"0966-0844","type":"print"},{"value":"1572-8773","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,6,3]]}}}