{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T17:02:17Z","timestamp":1759683737810,"version":"3.38.0"},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2011,4,1]],"date-time":"2011-04-01T00:00:00Z","timestamp":1301616000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biometals"],"published-print":{"date-parts":[[2011,10]]},"DOI":"10.1007\/s10534-011-9444-3","type":"journal-article","created":{"date-parts":[[2011,3,31]],"date-time":"2011-03-31T06:47:33Z","timestamp":1301554053000},"page":"903-914","source":"Crossref","is-referenced-by-count":5,"title":["Some characteristics of membrane Cd2+ transport in rat thymocytes: an analysis using Fluo-3"],"prefix":"10.1007","volume":"24","author":[{"given":"Takuya","family":"Kawanai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Fujinaga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuki","family":"Koizumi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isao","family":"Kurotani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erika","family":"Hashimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaya","family":"Satoh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoji","family":"Imai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norikazu","family":"Miyoshi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuo","family":"Oyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,4,1]]},"reference":[{"key":"9444_CR1","doi-asserted-by":"crossref","first-page":"C136","DOI":"10.1152\/ajpcell.00340.2007","volume":"294","author":"KW Au","year":"2008","unstructured":"Au KW, Siu CW, Lau CP, Tse HF, Li RA (2008) Structural and functional determinants in the S5-P region of HCN-encoded pacemaker channels revealed by cysteine-scanning substitutions. Am J Physiol Cell Physiol 294:C136\u2013C144","journal-title":"Am J Physiol Cell Physiol"},{"key":"9444_CR2","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0013-9351(05)80173-2","volume":"55","author":"P Borella","year":"1991","unstructured":"Borella P, Giardino A (1991) Lead and cadmium at very low doses affect in vitro immune response of human lymphocytes. Environ Res 55:165\u2013177","journal-title":"Environ Res"},{"key":"9444_CR3","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1196\/annals.1306.011","volume":"1012","author":"JP Bressler","year":"2004","unstructured":"Bressler JP, Olivi L, Cheong JH, Kim Y, Bannona D (2004) Divalent metal transporter 1 in lead and cadmium transport. Ann NY Acad Sci 1012:142\u2013152","journal-title":"Ann NY Acad Sci"},{"key":"9444_CR4","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/BF00711113","volume":"6","author":"P Camacho-Nasi","year":"1986","unstructured":"Camacho-Nasi P, Treistman SN (1986) Ethanol effects on voltage-dependent membrane conductances: comparative sensitivity of channel populations in Aplysia neurons. Cell Mol Neurobiol 6:263\u2013279","journal-title":"Cell Mol Neurobiol"},{"key":"9444_CR5","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1111\/j.1600-0773.1992.tb00543.x","volume":"71","author":"L Chikahisa","year":"1992","unstructured":"Chikahisa L, Oyama Y (1992) Tri-n-butyltin increases intracellular Ca2+ in mouse thymocytes: a flow-cytometric study using fluorescent dyes for membrane potential and intracellular Ca2+. Pharmacol Toxicol 71:190\u2013195","journal-title":"Pharmacol Toxicol"},{"key":"9444_CR6","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1254\/jjp.71.299","volume":"71","author":"L Chikahisa","year":"1996","unstructured":"Chikahisa L, Oyama Y, Okazaki E, Noda K (1996) Fluorescent estimation of H2O2-induced changes in cell viability and cellular nonprotein thiol level of dissociated rat thymocytes. Jpn J Pharmacol 71:299\u2013305","journal-title":"Jpn J Pharmacol"},{"key":"9444_CR7","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/S0026-895X(25)11220-0","volume":"13","author":"JH Chin","year":"1977","unstructured":"Chin JH, Goldstein DB (1977) Effects of low concentrations of ethanol on the fluidity of spin-labeled erythrocyte and brain membranes. Mol Pharmacol 13:435\u2013441","journal-title":"Mol Pharmacol"},{"key":"9444_CR8","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0162-3109(89)90012-X","volume":"18","author":"MG Cifone","year":"1989","unstructured":"Cifone MG, Alesse E, Di-Eugenio R, Napolitano T, Morrone S, Paolini R, Satoni G, Santoni A (1989) In vivo cadmium treatment alters natural killer activity and large granular lymphocyte number in the rat. Immunopharmacol 18:149\u2013156","journal-title":"Immunopharmacol"},{"key":"9444_CR9","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1113\/jphysiol.1984.sp015238","volume":"351","author":"G Cota","year":"1984","unstructured":"Cota G, Stefani E (1984) Saturation of calcium channels and surface charge effects in skeletal muscle fibres of the frog. J Physiol 351:135\u2013154","journal-title":"J Physiol"},{"key":"9444_CR10","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/0192-0561(93)90049-5","volume":"15","author":"JR Daum","year":"1993","unstructured":"Daum JR, Shephred DM, Noelle RJ (1993) Immunotoxicology of cadmium and mercury on B-lymphocytes. I. Effects on lymphocyte function. Int J Immunopharmacol 15:383\u2013394","journal-title":"Int J Immunopharmacol"},{"key":"9444_CR11","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1023\/A:1017970030131","volume":"222","author":"S Dong","year":"2001","unstructured":"Dong S, Shen HM, Ong CN (2001) Cadmium-induced apoptosis and phenotypic changes in mouse thymocytes. Mol Cell Biochem 222:11\u201320","journal-title":"Mol Cell Biochem"},{"key":"9444_CR12","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1016\/0306-4522(82)90249-4","volume":"7","author":"C Edwards","year":"1982","unstructured":"Edwards C (1982) The selectivity of ion channels in nerve and muscle. Neuroscience 7:1335\u20131366","journal-title":"Neuroscience"},{"key":"9444_CR13","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/0300-483X(94)90115-5","volume":"88","author":"B El Azzouzi","year":"1994","unstructured":"El Azzouzi B, Tsangaris GT, Pellegrini O, Manuel Y, Benveniste J, Thomas Y (1994) Cadmium induces apoptosis in a human T cell line. Toxicol 88:127\u2013139","journal-title":"Toxicol"},{"key":"9444_CR14","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S1532-0456(02)00009-1","volume":"131","author":"T Endo","year":"2002","unstructured":"Endo T (2002) Transport of cadmium across the apical membrane of epithelial cell lines. Comp Biochem Physiol C Toxicol Pharmacol 131:223\u2013229","journal-title":"Comp Biochem Physiol C Toxicol Pharmacol"},{"key":"9444_CR15","doi-asserted-by":"crossref","unstructured":"Fontaine J, Dewailly \u00c9, Benedetti JL, Pereg D, Ayotte P, D\u00e9ry S (2008) Re-evaluation of blood mercury, lead and cadmium concentrations in the Inuit population of Nunavik (Qu\u00e9bec): a cross-sectional study. Environ Health 7:25 http:\/\/www.ehjournal.net\/content\/7\/1\/25","DOI":"10.1186\/1476-069X-7-25"},{"key":"9444_CR16","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0378-4274(00)00178-8","volume":"115","author":"H Fujimaki","year":"2000","unstructured":"Fujimaki H, Ishido M, Nohara K (2000) Induction of apoptosis in mouse thymocytes by cadmium. Toxicol Lett 115:99\u2013105","journal-title":"Toxicol Lett"},{"key":"9444_CR17","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1023\/A:1020702213099","volume":"16","author":"MD Garrick","year":"2003","unstructured":"Garrick MD, Dolan KG, Horbinski C, Ghio AJ, Higgins D, Porubcin M, Moore EG, Hainsworth LN, Umbreit JN, Conrad ME, Feng L, Lis A, Roth JA, Singleton S, Garrick LM (2003) DMT1: a mammalian transporter for multiple metals. Biometals 16:41\u201354","journal-title":"Biometals"},{"key":"9444_CR18","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1042\/BJ20051987","volume":"398","author":"MD Garrick","year":"2006","unstructured":"Garrick MD, Kuo HC, Vargas F, Singleton S, Zhao L, Smith JJ, Paradkar P, Roth JA, Garrick LM (2006) Comparison of mammalian cell lines expressing distinct isoforms of divalent metal transporter 1 in a tetracycline-regulated fashion. Biochem J 398:539\u2013546","journal-title":"Biochem J"},{"key":"9444_CR19","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0006-2952(84)90476-3","volume":"33","author":"RJ Gerson","year":"1984","unstructured":"Gerson RJ, Shaikh ZA (1984) Differences in the uptake of cadmium and mercury by rat hepatocyte primary cultures. Role of a sulfhydryl carrier. Biochem Pharmacol 33:199\u2013203","journal-title":"Biochem Pharmacol"},{"key":"9444_CR20","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/S0006-3495(69)86396-4","volume":"9","author":"DL Gilbert","year":"1969","unstructured":"Gilbert DL, Ehrenstein G (1969) Effect of divalent cations on potassium conductance of squid axons: determination of surface charge. Biophys J 9:447\u2013963","journal-title":"Biophys J"},{"key":"9444_CR21","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1124\/mol.107.043588","volume":"73","author":"K Girijashanker","year":"2008","unstructured":"Girijashanker K, He L, Soleimani M, Reed JM, Li H, Liu Z, Wang B, Dalton TP, Nebert DW (2008) Slc39a14 gene encodes ZIP14, a metal\/bicarbonate symporter: similarities to the ZIP8 transporter. Mol Pharmacol 73:1413\u20131423","journal-title":"Mol Pharmacol"},{"key":"9444_CR22","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/0167-4889(89)90073-6","volume":"1011","author":"M Grazia-Cifone","year":"1989","unstructured":"Grazia-Cifone M, Alesse E, Procopio A, Paolini R, Di-Eugenio R, Santoni G, Santoni A (1989) Effects of cadmium on lymphocyte activation. Biochem Biophys Acta 1011:25\u201332","journal-title":"Biochem Biophys Acta"},{"key":"9444_CR23","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/0005-2736(85)90371-2","volume":"815","author":"AS Gukovskaya","year":"1985","unstructured":"Gukovskaya AS, Zinchenko VP (1985) The effects of ionophore A23187 and concanavalin A on the membrane potential of human peripheral blood lymphocytes and rat thymocytes. Biochim Biophys Acta 815:433\u2013440","journal-title":"Biochim Biophys Acta"},{"key":"9444_CR24","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1038\/41343","volume":"388","author":"H Gunshin","year":"1997","unstructured":"Gunshin H, Mackenzie B, Berger UV, Gunshin Y, Romero MF, Boron WF, Nussberger S, Gollan JL, Hediger MA (1997) Cloning and characterization of a mammalian proton-coupled metal-ion transporter. Nature 388:482\u2013488","journal-title":"Nature"},{"key":"9444_CR54","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/1742-4933-6-9","volume":"6","author":"H Haase","year":"2009","unstructured":"Haase H, Rink L (2009) The immune system and the impact of zinc during aging. Immun Ageing 6:9","journal-title":"Immun Ageing"},{"key":"9444_CR25","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1146\/annurev.ne.04.030181.000441","volume":"4","author":"S Hagiwara","year":"1981","unstructured":"Hagiwara S, Byerly L (1981) Calcium channel. Annu Rev Neurosci 4:69\u2013125","journal-title":"Annu Rev Neurosci"},{"key":"9444_CR26","first-page":"531","volume-title":"Handbook of fluorescent probes and research chemicals","author":"RP Haugland","year":"1996","unstructured":"Haugland RP (1996) Fluorescent indicators for Zn2+ and other metals. In: Spence M (ed) Handbook of fluorescent probes and research chemicals, 6th edn. Molecular Probes Inc., Eugene, pp 531\u2013540","edition":"6"},{"key":"9444_CR27","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1098\/rstb.1975.0011","volume":"270","author":"B Hille","year":"1975","unstructured":"Hille B, Woodhull AM, Shapiro BI (1975) Negative surface charge near sodium channels of nerve: divalent ions, monovalent ions, and pH. Philos Trans R Soc Lond B Biol Sci 270:301\u2013318","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"9444_CR55","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1016\/j.biochi.2009.04.002","volume":"91","author":"S Himeno","year":"2009","unstructured":"Himeno S, Yanagiya T, Fujishiro H (2009) The role of zinc transporters in cadmium and manganese transport in mammalian cells. Biochimie 91:1218\u20131222","journal-title":"Biochimie"},{"key":"9444_CR28","doi-asserted-by":"crossref","first-page":"8179","DOI":"10.1016\/S0021-9258(18)83166-0","volume":"264","author":"JP Kao","year":"1989","unstructured":"Kao JP, Harootunian AT, Tsien RY (1989) Photochemically generated cytosolic calcium pulses and their detection by fluo-3. J Biol Chem 264:8179\u20138184","journal-title":"J Biol Chem"},{"key":"9444_CR29","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1085\/jgp.89.4.629","volume":"89","author":"RS Kass","year":"1987","unstructured":"Kass RS, Krafte DS (1987) Negative surface charge density near heart calcium channels. Relevance to block by dihydropyridines. J Gen Physiol 89:629\u2013644","journal-title":"J Gen Physiol"},{"key":"9444_CR30","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0300-483X(99)00176-6","volume":"145","author":"MS Kim","year":"2000","unstructured":"Kim MS, Kim BJ, Woo HN, Kim KW, Kim KB, Kim IK, Jung YK (2000) Cadmium induces caspase-mediated cell death: suppression by Bcl-2. Toxicol 145:27\u201337","journal-title":"Toxicol"},{"key":"9444_CR31","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0887-2333(99)00089-2","volume":"14","author":"Z Krocova","year":"2000","unstructured":"Krocova Z, Macela A, Kroca M, Hernychova L (2000) The immunomodulatory effect(s) of lead and cadmium on the cells immune system in vitro. Toxicol In Vitro 14:33\u201340","journal-title":"Toxicol In Vitro"},{"key":"9444_CR32","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1085\/jgp.88.3.321","volume":"88","author":"JB Lansman","year":"1986","unstructured":"Lansman JB, Hess P, Tsien RW (1986) Blockade of current through single calcium channels by Cd2+, Mg2+, and Ca2+. Voltage and concentration dependence of calcium entry into the pore. J Gen Physiol 88:321\u2013347","journal-title":"J Gen Physiol"},{"key":"9444_CR33","doi-asserted-by":"crossref","first-page":"7710","DOI":"10.1002\/anie.201002853","volume":"49","author":"J Liang","year":"2010","unstructured":"Liang J, Canary JW (2010) Discrimination between hard metals with soft ligand donor atoms: an on-fluorescence probe for manganese(II). Angew Chem Int Ed 49:7710\u20137713","journal-title":"Angew Chem Int Ed"},{"key":"9444_CR34","doi-asserted-by":"crossref","first-page":"8171","DOI":"10.1016\/S0021-9258(18)83165-9","volume":"264","author":"A Minta","year":"1989","unstructured":"Minta A, Kao JP, Tsien RY (1989) Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores. J Biol Chem 264:8171\u20138178","journal-title":"J Biol Chem"},{"key":"9444_CR35","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/S0898-6568(01)00268-6","volume":"14","author":"UK Misra","year":"2002","unstructured":"Misra UK, Gawdi G, Akabani G, Pizzo SV (2002) Cadmium-induced DNA synthesis and cell proliferation in macrophages: the role of intracellular calcium and signal transduction mechanisms. Cell Signal 14:327\u2013340","journal-title":"Cell Signal"},{"key":"9444_CR36","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1085\/jgp.83.6.941","volume":"83","author":"DA Nachshen","year":"1984","unstructured":"Nachshen DA (1984) Selectivity of the Ca binding site in synaptosome Ca channels. Inhibition of Ca influx by multivalent metal cations. J Gen Physiol 83:941\u2013967","journal-title":"J Gen Physiol"},{"key":"9444_CR37","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1113\/jphysiol.1977.sp011821","volume":"267","author":"H Ohmori","year":"1977","unstructured":"Ohmori H, Yoshii M (1977) Surface potential reflected in both gating and permeation mechanisms of sodium and calcium channels of the tunicate egg cell membrane. J Physiol 267:429\u2013463","journal-title":"J Physiol"},{"key":"9444_CR38","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1254\/jjp.71.273","volume":"71","author":"E Okazaki","year":"1996","unstructured":"Okazaki E, Chikahisa L, Kanemaru K, Oyama Y (1996) Flow cytometric analysis of the H2O2-induced increase in intracellular Ca2+ concentration of rat thymocytes. Jpn J Pharmacol 71:273\u2013280","journal-title":"Jpn J Pharmacol"},{"key":"9444_CR39","doi-asserted-by":"crossref","first-page":"C793","DOI":"10.1152\/ajpcell.2001.281.3.C793","volume":"281","author":"L Olivi","year":"2001","unstructured":"Olivi L, Sisk J, Bressler J (2001) Involvement of DMT1 in uptake of Cd in MDCK cells: role of protein kinase C. Am J Physiol Cell Physiol 281:C793\u2013C800","journal-title":"Am J Physiol Cell Physiol"},{"key":"9444_CR40","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/0006-8993(86)90190-3","volume":"376","author":"Y Oyama","year":"1986","unstructured":"Oyama Y, Akaike N, Nishi K (1986) Effects of n-alkanols on the calcium current of intracellularly perfused neurons of Helix aspersa. Brain Res 376:280\u2013284","journal-title":"Brain Res"},{"key":"9444_CR42","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S1382-6689(01)00112-0","volume":"11","author":"Y Oyama","year":"2002","unstructured":"Oyama Y, Arata T, Chikahisa L, Soeda F, Takahama K (2002) Estimation of increased concentration of intracellular Cd2+ by fluo-3 in rat thymocytes exposed to CdCl2. Environ Toxicol Pharmacol 11:111\u2013118","journal-title":"Environ Toxicol Pharmacol"},{"key":"9444_CR43","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.toxlet.2006.12.009","volume":"169","author":"N Pathak","year":"2007","unstructured":"Pathak N, Khandelwal (2007) Role of oxidative stress and apoptosis in cadmium induced thymic atrophy and splenomegaly in mice. Toxicol Lett 169:95\u2013108","journal-title":"Toxicol Lett"},{"key":"9444_CR44","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/S0896-6273(00)80107-5","volume":"16","author":"LS Premkumar","year":"1996","unstructured":"Premkumar LS, Auerbach A (1996) Identification of a high affinity divalent cation binding site near the entrance of the NMDA receptor channel. Neuron 16:869\u2013880","journal-title":"Neuron"},{"key":"9444_CR45","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1002\/jcp.1040700107","volume":"70","author":"AF Rega","year":"1967","unstructured":"Rega AF, Rothstein A, Weed RI (1967) Erythrocyte membrane sulfhydryl groups and the active transport of cations. J Cell Physiol 70:45\u201352","journal-title":"J Cell Physiol"},{"key":"9444_CR46","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/0896-6273(93)90150-P","volume":"11","author":"MJ Root","year":"1993","unstructured":"Root MJ, MacKinnon R (1993) Identification of an external divalent cation-binding site in the pore of a cGMP-activated channel. Neuron 11:459\u2013466","journal-title":"Neuron"},{"key":"9444_CR47","first-page":"149","volume-title":"Metal ions in biology and medicine","author":"T Sch\u00e4fer","year":"1994","unstructured":"Sch\u00e4fer T, Benters J, Beyersmann D (1994) Cadmium uptake and interference with receptor-mediated calcium mobilization in PC12 cells. In: Collery P, Poirier LA, Littlefield NA, Etienne JC (eds) Metal ions in biology and medicine. John Libbey Eurotext, Paris, pp 149\u2013154"},{"key":"9444_CR48","doi-asserted-by":"crossref","first-page":"2528","DOI":"10.1016\/S0006-3495(02)75264-8","volume":"83","author":"H Soh","year":"2002","unstructured":"Soh H, Park CS (2002) Localization of divalent cation-binding site in the pore of a small conductance Ca2+-activated K+ channel and its role in determining current-voltage relationship. Biophys J 83:2528\u20132538","journal-title":"Biophys J"},{"key":"9444_CR49","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S0300-483X(97)00057-7","volume":"120","author":"V Souza","year":"1997","unstructured":"Souza V, Bucio L, Guti\u00e9rrez-Ruiz MC (1997) Cadmium uptake by a human hepatic cell line (WRL-68 cells). Toxicol 120:215\u2013220","journal-title":"Toxicol"},{"key":"9444_CR50","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1038\/35036318","volume":"2","author":"R Strotmann","year":"2000","unstructured":"Strotmann R, Harteneck C, Nunnenmacher K, Schultz G, Plant TD (2000) OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity. Nat Cell Biol 2:695\u2013702","journal-title":"Nat Cell Biol"},{"key":"9444_CR51","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0300-483X(98)00032-8","volume":"128","author":"GT Tsangaris","year":"1998","unstructured":"Tsangaris GT, Tzortzatou-Stathopoulou F (1998) Cadmium induces apoptosis differentially on immune system cell lines. Toxicol 128:143\u2013150","journal-title":"Toxicol"},{"key":"9444_CR52","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.taap.2007.05.017","volume":"223","author":"M Viau","year":"2007","unstructured":"Viau M, Collin-Faure V, Richaud P, Ravanat JL, Cand\u00e9ias SM (2007) Cadmium and T cell differentiation: limited impact in vivo but significant toxicity in fetal thymus organ culture. Toxicol Appl Pharmacol 223:257\u2013266","journal-title":"Toxicol Appl Pharmacol"},{"key":"9444_CR53","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1002\/jcp.1041250110","volume":"125","author":"HA Wilson","year":"1985","unstructured":"Wilson HA, Chused TM (1985) Lymphocyte membrane potential and Ca2+-sensitive potassium channels described by oxonol dye fluorescence measurements. J Cell Physiol 125:72\u201381","journal-title":"J Cell Physiol"}],"container-title":["BioMetals"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10534-011-9444-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10534-011-9444-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10534-011-9444-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T19:21:41Z","timestamp":1741116101000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10534-011-9444-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,4,1]]},"references-count":54,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2011,10]]}},"alternative-id":["9444"],"URL":"https:\/\/doi.org\/10.1007\/s10534-011-9444-3","relation":{},"ISSN":["0966-0844","1572-8773"],"issn-type":[{"type":"print","value":"0966-0844"},{"type":"electronic","value":"1572-8773"}],"subject":[],"published":{"date-parts":[[2011,4,1]]}}}