{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T04:12:09Z","timestamp":1783743129077,"version":"3.55.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T00:00:00Z","timestamp":1778112000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T00:00:00Z","timestamp":1778112000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["25DIVSUP1477011"],"award-info":[{"award-number":["25DIVSUP1477011"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["24TPA1280217"],"award-info":[{"award-number":["24TPA1280217"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["1R01HL159960-01A1"],"award-info":[{"award-number":["1R01HL159960-01A1"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Biomed Microdevices"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1007\/s10544-026-00812-2","type":"journal-article","created":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T11:22:23Z","timestamp":1778152943000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Transcriptomic profiling of radiopaque nanoparticle-loaded, bioresorbable polymeric perivascular wrap for arteriovenous fistula maturation"],"prefix":"10.1007","volume":"28","author":[{"given":"Allan John R.","family":"Barcena","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marvin R.","family":"Bernardino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominic Karl M.","family":"Bolinas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kitz Paul D.","family":"Marco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna E.","family":"Marks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tosha Mae S.","family":"Manalastas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Archana","family":"Mishra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie","family":"Fowlkes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard R.","family":"Bouchard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jizhong","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven Y.","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marites P.","family":"Melancon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,7]]},"reference":[{"key":"812_CR2","doi-asserted-by":"crossref","unstructured":"A.J.R. Barcena, J.V.D. Perez, M.R. Bernardino, J.A. Damasco, A. Cortes, H.C. Del Mundo, E.M.D. San Valentin, C. Klusman, G.M. Canlas, F.M. Heralde III., R. Avritscher, N. Fowlkes, R.R. Bouchard, J. Cheng, S.Y. Huang, M.P. Melancon, Bioresorbable mesenchymal stem cell-loaded electrospun polymeric scaffold inhibits neointimal hyperplasia following arteriovenous fistula formation in a rat model of chronic kidney disease. Adv. Healthc. Mater. 12(26), 2300960 (2023a)","DOI":"10.1002\/adhm.202300960"},{"issue":"14","key":"812_CR3","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241411754","volume":"24","author":"AJR Barcena","year":"2023","unstructured":"A.J.R. Barcena, J.V.D. Perez, J.A. Damasco, M.R. Bernardino, E.M.D. San Valentin, C. Klusman, B. Martin, A. Cortes, G.M. Canlas, H.C. Del Mundo, F.M. Heralde, R. Avritscher, N. Fowlkes, R.R. Bouchard, J. Cheng, S.Y. Huang, M.P. Melancon, Gold nanoparticles for monitoring of mesenchymal stem-cell-loaded bioresorbable polymeric wraps for arteriovenous fistula maturation. Int. J. Mol. Sci. 24(14), 11754 (2023b)","journal-title":"Int. J. Mol. Sci."},{"issue":"26","key":"812_CR4","doi-asserted-by":"publisher","first-page":"33159","DOI":"10.1021\/acsami.4c06042","volume":"16","author":"AJR Barcena","year":"2024","unstructured":"A.J.R. Barcena, J.V.D. Perez, M.R. Bernardino, E.M.D. San Valentin, J.A. Damasco, C. Klusman, B. Martin, K.A. Court, B. Godin, G. Canlas, N. Fowlkes, R.R. Bouchard, J. Cheng, S.Y. Huang, M.P. Melancon, Controlled delivery of rosuvastatin or rapamycin through electrospun bismuth nanoparticle-infused perivascular wraps promotes arteriovenous fistula maturation. ACS Appl. Mater. Interfaces 16(26), 33159\u201333168 (2024)","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"812_CR5","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioadv.2024.214052","volume":"166","author":"AJR Barcena","year":"2025","unstructured":"A.J.R. Barcena, J.V.D. Perez, M.R. Bernardino, J.A. Damasco, E.M.D. San Valentin, C. Klusman, B. Martin, G.M. Canlas, F.M. Heralde, N. Fowlkes, R.R. Bouchard, J. Cheng, S.Y. Huang, M.P. Melancon, Bismuth-infused perivascular wrap facilitates delivery of mesenchymal stem cells and attenuation of neointimal hyperplasia in rat arteriovenous fistulas. Biomater. Adv. 166, 214052 (2025)","journal-title":"Biomater. Adv."},{"key":"812_CR6","doi-asserted-by":"crossref","unstructured":"A.J.R. Barcena, J.V.D. Perez, O. Liu, A. Mu, F.M. Heralde 3rd, S.Y. Huang, M.P. Melancon, Localized perivascular therapeutic approaches to inhibit venous neointimal hyperplasia in arteriovenous fistula ac cess for hemodialysis use. Biomolecules. 12(10), 1367 (2022)","DOI":"10.3390\/biom12101367"},{"key":"812_CR7","doi-asserted-by":"crossref","unstructured":"A. Brahmbhatt, A. Remuzzi, M. Franzoni, S. Misra, The molecular mechanisms of hemodialysis vascular access failure. Kidney Int. 89(2), 303\u2013316 (2016)","DOI":"10.1016\/j.kint.2015.12.019"},{"key":"812_CR8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsvi.2025.100205","volume":"3","author":"MA Hussain","year":"2025","unstructured":"M.A. Hussain, C.K. Ozaki, D. Nation, J. Burgess, D.M. Hentschel, C.S. Settle, J.F. Lucas, E. Dillavou, A. Farber, Extravascular supported arteriovenous fistulas reduced the need for interventions to support maturation and time to achieve two-needle cannulation for end-stage kidney disease patients in a multicenter US study. JVS-Vascular Insights 3, 100205 (2025)","journal-title":"JVS-Vascular Insights"},{"issue":"11","key":"812_CR9","doi-asserted-by":"publisher","first-page":"1947","DOI":"10.1002\/pro.3715","volume":"28","author":"M Kanehisa","year":"2019","unstructured":"M. Kanehisa, Toward understanding the origin and evolution of cellular organisms. Protein Sci. 28(11), 1947\u20131951 (2019)","journal-title":"Protein Sci."},{"issue":"1","key":"812_CR10","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1093\/nar\/28.1.27","volume":"28","author":"M Kanehisa","year":"2000","unstructured":"M. Kanehisa, S. Goto, KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res. 28(1), 27\u201330 (2000)","journal-title":"Nucleic Acids Res."},{"issue":"D1","key":"812_CR11","doi-asserted-by":"publisher","first-page":"D672","DOI":"10.1093\/nar\/gkae909","volume":"53","author":"M Kanehisa","year":"2024","unstructured":"M. Kanehisa, M. Furumichi, Y. Sato, Y. Matsuura, M. Ishiguro-Watanabe, KEGG: biological systems database as a model of the real world. Nucleic Acids Res. 53(D1), D672\u2013D677 (2024)","journal-title":"Nucleic Acids Res."},{"issue":"1","key":"812_CR12","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1053\/j.ajkd.2019.05.023","volume":"75","author":"N Karydis","year":"2020","unstructured":"N. Karydis, P. Bevis, T. Beckitt, D. Silverberg, M. Halak, F. Calder, An implanted blood vessel support device for arteriovenous fistulas: a randomized controlled trial. Am. J. Kidney Dis. 75(1), 45\u201353 (2020)","journal-title":"Am. J. Kidney Dis."},{"issue":"8","key":"812_CR13","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1038\/s41587-019-0201-4","volume":"37","author":"D Kim","year":"2019","unstructured":"D. Kim, J.M. Paggi, C. Park, C. Bennett, S.L. Salzberg, Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype. Nat. Biotechnol. 37(8), 907\u2013915 (2019)","journal-title":"Nat. Biotechnol."},{"issue":"6","key":"812_CR14","doi-asserted-by":"publisher","first-page":"1986","DOI":"10.1007\/s42765-023-00315-2","volume":"5","author":"C Klusman","year":"2023","unstructured":"C. Klusman, B. Martin, J.V.D. Perez, J.R. Barcena Allan, M.R. Bernardino, E.M.D.S. Valentin, J.A. Damasco, H.C. Del Mundo, K.A. Court, B. Godin, G.M. Canlas, N. Fowlkes, R. Bouchard, J. Cheng, S.Y. Huang, M.P. Melancon, Rosuvastatin-eluting gold-nanoparticle-loaded perivascular wrap for enhanced arteriovenous fistula maturation in a murine model. Adv. Fiber Mater. 5(6), 1986\u20132001 (2023)","journal-title":"Adv. Fiber Mater."},{"issue":"7","key":"812_CR15","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1093\/bioinformatics\/btt656","volume":"30","author":"Y Liao","year":"2013","unstructured":"Y. Liao, G.K. Smyth, W. Shi, FeatureCounts: an efficient general purpose program for assigning sequence reads to genomic features. Bioinformatics 30(7), 923\u2013930 (2013)","journal-title":"Bioinformatics"},{"issue":"14","key":"812_CR16","doi-asserted-by":"publisher","first-page":"1830","DOI":"10.1093\/bioinformatics\/btt285","volume":"29","author":"W Luo","year":"2013","unstructured":"W. Luo, C. Brouwer, Pathview: an R\/Bioconductor package for pathway-based data integration and visualization. Bioinformatics 29(14), 1830\u20131831 (2013)","journal-title":"Bioinformatics"},{"key":"812_CR17","doi-asserted-by":"crossref","unstructured":"L. Martinez, M.G. Rojas, M. Tabbara, S. Pereira-Simon, N.S. Falcon, M.A. Rauf, A. Challa, Z.M. Zigmond, A.J. Griswold, J.C. Duque, R.M. Lassance-Soares, O.C. Velazquez, L.H. Salman, R.I. Vazquez-Padron, The transcriptomics of the human vein transformation after arteriovenous fistula anastomosis uncovers layer-specific remodeling and hallmarks of maturation failure. Kidney Int. Rep. 8(4), 837\u2013850 (2023)","DOI":"10.1016\/j.ekir.2023.01.008"},{"key":"812_CR18","doi-asserted-by":"crossref","unstructured":"L. Martinez, F.F. Stoyell-Conti, M. Tabbara, M.G. Rojas, S. Pereira-Simon, N.S. Falcon, R.H. Lopez, D. Galtes, C. Kosanovic, A.J. Griswold, X. Yang, Y.-T. Shiu, T. Lee, J.C. Duque, M.A. Ladino, L.H. Salman, X. Long, R.I. Vazquez-Padron, The single-cell landscape of the human vein after arteriovenous fistula creation and implications for maturation failure. Kidney Int. 109(1), 160\u2013177 (2026)","DOI":"10.1016\/j.kint.2025.08.024"},{"issue":"1","key":"812_CR19","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-64075-8","volume":"14","author":"Y Ohashi","year":"2024","unstructured":"Y. Ohashi, C.D. Protack, Y. Aoyagi, L. Gonzalez, C. Thaxton, W. Zhang, M. Kano, H. Bai, B. Yatsula, R. Alves, K. Hoshina, E.B. Schneider, X. Long, R.J. Perry, A. Dardik, Heterogeneous gene expression during early arteriovenous fistula remodeling suggests that downregulation of metabolism predicts adaptive venous remodeling. Sci. Rep. 14(1), 13287 (2024)","journal-title":"Sci. Rep."},{"issue":"3","key":"812_CR20","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1038\/nbt.3122","volume":"33","author":"M Pertea","year":"2015","unstructured":"M. Pertea, G.M. Pertea, C.M. Antonescu, T.-C. Chang, J.T. Mendell, S.L. Salzberg, StringTie enables improved reconstruction of a transcriptome from RNA-seq reads. Nat. Biotechnol. 33(3), 290\u2013295 (2015)","journal-title":"Nat. Biotechnol."},{"key":"812_CR21","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20215387","author":"N Sadaghianloo","year":"2019","unstructured":"N. Sadaghianloo, J. Contenti, A. Dardik, N.M. Mazure, Role of hypoxia and metabolism in the development of neointimal hyperplasia in arteriovenous fistulas. Int. J. Mol. Sci. 20(21), 5387 (2019). https:\/\/doi.org\/10.3390\/ijms20215387","journal-title":"Int. J. Mol. Sci."},{"issue":"10","key":"812_CR22","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1038\/nbt1340","volume":"25","author":"H Soo Choi","year":"2007","unstructured":"H. Soo Choi, W. Liu, P. Misra, E. Tanaka, J.P. Zimmer, B. Itty Ipe, M.G. Bawendi, J.V. Frangioni, Renal clearance of quantum dots. Nat. Biotechnol. 25(10), 1165\u20131170 (2007)","journal-title":"Nat. Biotechnol."},{"key":"812_CR23","doi-asserted-by":"crossref","unstructured":"X. Wang, M.A. Chaudhry, Y. Nie, Z. Xie, J.I. Shapiro, J. Liu, A mouse 5\/6th nephrectomy model that induces experimental uremic cardiomyopathy. J. Vis. Exp. (129), 55825 (2017)","DOI":"10.3791\/55825"},{"key":"812_CR24","first-page":"e53294","volume":"108","author":"CY Wong","year":"2016","unstructured":"C.Y. Wong, M.R. de Vries, Y. Wang, J.R. van der Vorst, A.L. Vahrmeijer, A.J. van Zonneveld, J.F. Hamming, P. Roy-Chaudhury, T.J. Rabelink, P.H. Quax, J.I. Rotmans, A novel murine model of arteriovenous fistula failure: the surgical procedure in detail. J. Vis. Exp. 108, e53294 (2016)","journal-title":"J. Vis. Exp."},{"issue":"3","key":"812_CR25","first-page":"100141","volume":"2","author":"T Wu","year":"2021","unstructured":"T. Wu, E. Hu, S. Xu, M. Chen, P. Guo, Z. Dai, T. Feng, L. Zhou, W. Tang, L. Zhan, X. Fu, S. Liu, X. Bo, G. Yu, clusterProfiler 4.0: a universal enrichment tool for interpreting omics data. Innovation (Camb.) 2(3), 100141 (2021)","journal-title":"Innovation (Camb.)"},{"key":"812_CR26","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25179519","author":"R Yan","year":"2024","unstructured":"R. Yan, A. Song, C. Zhang, R. Yan, A. Song, C. Zhang, The pathological mechanisms and therapeutic molecular targets in arteriovenous fistula dysfunction. Int. J. Mol. Sci. 25(17), 9519 (2024). https:\/\/doi.org\/10.3390\/ijms25179519","journal-title":"Int. J. Mol. Sci."},{"key":"812_CR27","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1007\/978-1-0716-0301-7_11","volume":"2117","author":"G Yu","year":"2020","unstructured":"G. Yu, Gene ontology semantic similarity analysis using GOSemSim. Methods Mol. Biol. 2117, 207\u2013215 (2020)","journal-title":"Methods Mol. Biol."},{"issue":"12","key":"812_CR28","doi-asserted-by":"publisher","first-page":"1718","DOI":"10.1002\/adfm.201302312","volume":"24","author":"XD Zhang","year":"2014","unstructured":"X.D. Zhang, J. Chen, Y. Min, G.B. Park, X. Shen, S.S. Song, Y.M. Sun, H. Wang, W. Long, J. Xie, Metabolizable Bi2Se3 nanoplates: biodistribution, toxicity, and uses for cancer radiation therapy and imaging. Adv. Funct. Mater. 24(12), 1718\u20131729 (2014)","journal-title":"Adv. Funct. Mater."}],"container-title":["Biomedical Microdevices"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10544-026-00812-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10544-026-00812-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10544-026-00812-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T03:27:17Z","timestamp":1783740437000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10544-026-00812-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,7]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["812"],"URL":"https:\/\/doi.org\/10.1007\/s10544-026-00812-2","relation":{},"ISSN":["1387-2176","1572-8781"],"issn-type":[{"value":"1387-2176","type":"print"},{"value":"1572-8781","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,7]]},"assertion":[{"value":"10 February 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 April 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"34"}}