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Main diseases causing movement disorders are metal\u2010storage diseases, neurotransmitter synthesis defects, energy metabolism disorders and lysosomal storage diseases. IEMs should not be missed as many are treatable. Here we briefly review IEMs causing movement disorders in adolescence and adults and propose a simple diagnostic approach to guide metabolic investigations based on the clinical course of symptoms, the type of abnormal movements, and brain MRI abnormalities.<\/jats:p>","DOI":"10.1007\/s10545-008-0854-5","type":"journal-article","created":{"date-parts":[[2008,6,18]],"date-time":"2008-06-18T12:23:06Z","timestamp":1213791786000},"page":"308-318","source":"Crossref","is-referenced-by-count":63,"title":["Movement disorders and inborn errors of metabolism in adults: A diagnostic approach"],"prefix":"10.1002","volume":"31","author":[{"given":"F.","family":"Sedel","sequence":"first","affiliation":[{"name":"Federation of Nervous System Diseases Salp\u00eatri\u00e8re Hospital Assistance Publique H\u00f4pitaux de Paris Paris France"},{"name":"Neurometabolic Unit, Federation of Nervous System Diseases, and Reference Center for Lysosomal Diseases Salp\u00eatri\u00e8re Hospital 47 Boulevard de 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