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After demonstrating mild gait disturbance beginning at the age of 4 years, he was diagnosed with NPC at age 12 on the basis of 95% of cultured fibroblasts staining positive for filipin and a reduced fibroblast cholesterol esterification rate. He then developed a seizure disorder at age 15, where clusters of seizures produced typical psychotic symptoms, including hallucinations and delusions. His seizure disorder responded to valproate, which resulted in a settling of his psychotic symptoms. Whilst post\u2010ictal psychosis is rarely reported prior to the age of 16, NPC in adolescents and adults is particularly psychotogenic and may increase the risk for post\u2010ictal psychosis in the pediatric population.<\/jats:p>","DOI":"10.1007\/s10545-009-9021-x","type":"journal-article","created":{"date-parts":[[2010,1,12]],"date-time":"2010-01-12T15:59:30Z","timestamp":1263311970000},"page":"63-65","source":"Crossref","is-referenced-by-count":16,"title":["Post\u2010ictal psychosis in adolescent Niemann\u2010Pick disease type C"],"prefix":"10.1002","volume":"33","author":[{"given":"Mark","family":"Walterfang","sequence":"first","affiliation":[{"name":"Neuropsychiatry Unit Royal Melbourne Hospital Melbourne VIC Australia"},{"name":"Melbourne Neuropsychiatry Centre University of Melbourne Melbourne VIC Australia"},{"name":"Royal Melbourne Hospital 3050, Level 2, John Cade Building Melbourne VIC 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