{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T07:00:55Z","timestamp":1780470055567,"version":"3.54.1"},"reference-count":2,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,2,6]],"date-time":"2013-02-06T00:00:00Z","timestamp":1360108800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Inher Metab Disea"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The case of a 10\u2010year\u2010old boy with Farber lipogranulomatosis with predominant joint involvement, subacute, laryngeal and tongue granulomas, microcytic anemia, elevated ESR and CRP, is presented. The boy had no signs of CNS and internal organ involvement. The disease manifested at 6 months; at 11 months the boy had widespread granulomatous polyarthritis with contractures, and juvenile idiopathic arthritis (JIA) was suggested. All antirheumatic therapies failed. Immunologic assessment revealed elevated serum interleukin\u20101\u03b2, increased T\u2010helper, NK and CD25\u2010positive cells, and circulating immune complexes. Our case with predominant rheumatologic manifestations illustrates a differential diagnosis of JIA.<\/jats:p>","DOI":"10.1007\/s10545-012-9573-z","type":"journal-article","created":{"date-parts":[[2013,2,5]],"date-time":"2013-02-05T12:59:20Z","timestamp":1360069160000},"page":"1079-1080","source":"Crossref","is-referenced-by-count":24,"title":["Farber lipogranulomatosis with predominant joint involvement mimicking juvenile idiopathic arthritis"],"prefix":"10.1002","volume":"36","author":[{"given":"Mikhail M.","family":"Kostik","sequence":"first","affiliation":[{"name":"Hospital Pediatric Department Saint\u2010Petersburg State Pediatric Medical University Lytovskaya 2 Saint\u2010Petersburg 194100 Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irina A.","family":"Chikova","sequence":"additional","affiliation":[{"name":"Hospital Pediatric Department Saint\u2010Petersburg State Pediatric Medical University Lytovskaya 2 Saint\u2010Petersburg 194100 Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladislav V.","family":"Avramenko","sequence":"additional","affiliation":[{"name":"Department of Pediatric Ortopedics and Traumatology Saint\u2010Petersburg State Pediatric Medical University Lytovskaya 2 Saint\u2010Petersburg 194100 Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laly I.","family":"Vasyakina","sequence":"additional","affiliation":[{"name":"Department of Immunology Federal Institute of Public Health \u00abThe Nikiforov's Russian Center of Emergency and Radiation Medicine\u00bb Saint\u2010Petersburg Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuelle","family":"Le Trionnaire","sequence":"additional","affiliation":[{"name":"Laboratoire de Biochimie M\u00e9tabolique, Institut F\u00e9d\u00e9ratif de Biologie, CHU Purpan Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vyacheslav G.","family":"Chasnyk","sequence":"additional","affiliation":[{"name":"Hospital Pediatric Department Saint\u2010Petersburg State Pediatric Medical University Lytovskaya 2 Saint\u2010Petersburg 194100 Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Levade","sequence":"additional","affiliation":[{"name":"Department of Immunology Federal Institute of Public Health \u00abThe Nikiforov's Russian Center of Emergency and Radiation Medicine\u00bb Saint\u2010Petersburg Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,2,6]]},"reference":[{"key":"e_1_2_3_2_1","volume-title":"Scriver's OMMBID (Online Metabolic and Molecular Bases of Inherited disease)","author":"Levade T","year":"2009"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1006\/geno.1999.5940"}],"container-title":["Journal of Inherited Metabolic Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s10545-012-9573-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T07:37:18Z","timestamp":1694763438000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s10545-012-9573-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,6]]},"references-count":2,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["10.1007\/s10545-012-9573-z"],"URL":"https:\/\/doi.org\/10.1007\/s10545-012-9573-z","archive":["Portico"],"relation":{},"ISSN":["0141-8955","1573-2665"],"issn-type":[{"value":"0141-8955","type":"print"},{"value":"1573-2665","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,6]]}}}