{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T13:47:32Z","timestamp":1762004852117,"version":"3.37.3"},"reference-count":2,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,2,3]],"date-time":"2017-02-03T00:00:00Z","timestamp":1486080000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2017,2,3]],"date-time":"2017-02-03T00:00:00Z","timestamp":1486080000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100003593","name":"CNPq","doi-asserted-by":"crossref","award":["483508\/2013-6"],"award-info":[{"award-number":["483508\/2013-6"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"crossref"}]},{"name":"FIPE-HCPA","award":["15-0322"],"award-info":[{"award-number":["15-0322"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J of Inher Metab Disea"],"published-print":{"date-parts":[[2017,5]]},"DOI":"10.1007\/s10545-017-0014-x","type":"journal-article","created":{"date-parts":[[2017,2,3]],"date-time":"2017-02-03T07:34:18Z","timestamp":1486107258000},"page":"311-312","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Losartan improves aortic dilatation and cardiovascular disease in mucopolysaccharidosis I"],"prefix":"10.1002","volume":"40","author":[{"given":"Esteban Alberto","family":"Gonzalez","sequence":"first","affiliation":[{"name":"Gene Therapy Center, Hospital de Cl\u00ednicas de Porto Alegre Ramiro Barcelos, 2350 Porto Alegre 90035\u2010903 Brazil"},{"name":"Postgraduate Program in Genetics and Molecular Biology, UFRGS Porto Alegre Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela Maria Vicente","family":"Tavares","sequence":"additional","affiliation":[{"name":"Gene Therapy Center, Hospital de Cl\u00ednicas de Porto Alegre Ramiro Barcelos, 2350 Porto Alegre 90035\u2010903 Brazil"},{"name":"Postgraduate Program in Physiology\u2010UFRGS Porto Alegre Brazil"},{"name":"Ritter dos Reis University Center\u2010UniRitter Porto Alegre Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edina","family":"Poletto","sequence":"additional","affiliation":[{"name":"Gene Therapy Center, Hospital de Cl\u00ednicas de Porto Alegre Ramiro Barcelos, 2350 Porto Alegre 90035\u2010903 Brazil"},{"name":"Postgraduate Program in Genetics and Molecular Biology, UFRGS Porto Alegre Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Giugliani","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Genetics and Molecular Biology, UFRGS Porto Alegre Brazil"},{"name":"Medical Genetics Service, Hospital de Cl\u00ednicas de Porto Alegre Porto Alegre Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ursula","family":"Matte","sequence":"additional","affiliation":[{"name":"Gene Therapy Center, Hospital de Cl\u00ednicas de Porto Alegre Ramiro Barcelos, 2350 Porto Alegre 90035\u2010903 Brazil"},{"name":"Postgraduate Program in Genetics and Molecular Biology, UFRGS Porto Alegre Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guilherme","family":"Baldo","sequence":"additional","affiliation":[{"name":"Gene Therapy Center, Hospital de Cl\u00ednicas de Porto Alegre Ramiro Barcelos, 2350 Porto Alegre 90035\u2010903 Brazil"},{"name":"Postgraduate Program in Genetics and Molecular Biology, UFRGS Porto Alegre Brazil"},{"name":"Postgraduate Program in Physiology\u2010UFRGS Porto Alegre Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,2,3]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_5_2_1","DOI":"10.1016\/j.ymgme.2011.08.018"},{"unstructured":"OsbornMJWebberBRMcElmurryRTRudserKDDeFeoAPMuradianMPetrykAHallgrimssonBBlazarBRTolarJetalAngiotensin receptor blockade mediated amelioration of mucopolysaccharidosis type I cardiac and craniofacial pathologyJ Inherit Metab Dis20165335863","key":"e_1_2_5_3_1"}],"container-title":["Journal of Inherited Metabolic Disease"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10545-017-0014-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10545-017-0014-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10545-017-0014-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s10545-017-0014-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T07:20:37Z","timestamp":1694762437000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s10545-017-0014-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,3]]},"references-count":2,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["10.1007\/s10545-017-0014-x"],"URL":"https:\/\/doi.org\/10.1007\/s10545-017-0014-x","archive":["Portico"],"relation":{},"ISSN":["0141-8955","1573-2665"],"issn-type":[{"type":"print","value":"0141-8955"},{"type":"electronic","value":"1573-2665"}],"subject":[],"published":{"date-parts":[[2017,2,3]]}}}