{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T21:18:41Z","timestamp":1793395121304,"version":"4.5.0"},"reference-count":99,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2006,4,1]],"date-time":"2006-04-01T00:00:00Z","timestamp":1143849600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Breast Cancer Res Treat"],"published-print":{"date-parts":[[2006,10]]},"DOI":"10.1007\/s10549-006-9219-7","type":"journal-article","created":{"date-parts":[[2006,3,31]],"date-time":"2006-03-31T09:13:38Z","timestamp":1143796418000},"page":"351-364","source":"Crossref","is-referenced-by-count":104,"title":["Capsaicin-induced inactivation of sensory neurons promotes a more aggressive gene expression phenotype in breast cancer cells"],"prefix":"10.1007","volume":"99","author":[{"given":"Nuray","family":"Erin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Bylander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary","family":"Chase","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary","family":"Clawson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2006,4,1]]},"reference":[{"key":"9219_CR1","doi-asserted-by":"crossref","unstructured":"2003 Marimastat: BB2516, TA2516. Drugs Res Dev 4:198\u2013203","DOI":"10.2165\/00126839-200304030-00011"},{"key":"9219_CR2","doi-asserted-by":"crossref","first-page":"8823","DOI":"10.1073\/pnas.95.15.8823","volume":"95","author":"S Ambs","year":"1998","unstructured":"Ambs S, Ogunfusika M, Merriam W, Bennett W, Billiar T, Harris C (1998) Up-regulation of inducible nitric oxide synthase expression in cancer-prone p53 knockout mice. Proc Natl Acad Sci(USA) 95:8823\u20138828","journal-title":"Proc Natl Acad Sci(USA)"},{"key":"9219_CR3","doi-asserted-by":"crossref","first-page":"3936","DOI":"10.1182\/blood.V89.11.3936","volume":"89","author":"Y Arai","year":"1997","unstructured":"Arai Y, Hosoda F, Kobayashi H, Arai K, Hayashi Y, Kamada N, Kaneko Y, Ohki M (1997) The inv(11)(p15q22) chromosome translocation of de novo and therapy-related myeloid malignancies results in fusion of the nucleoporin gene, NUP98, with the putative RNA helicase gene DDX10. Blood 89:3936\u20133944","journal-title":"Blood"},{"key":"9219_CR4","first-page":"1399","volume":"52","author":"C Aslakson","year":"1992","unstructured":"Aslakson C, Miller F (1992) Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor. Cancer Res 52:1399\u2013405","journal-title":"Cancer Res"},{"key":"9219_CR5","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1023\/A:1014993006190","volume":"72","author":"J Barrett","year":"2002","unstructured":"Barrett J, Puglia M, Singh G, Tozer R (2002) Expression of Ets-related transcription factors and matrix metalloproteinase genes in human breast cancer cells. Breast Can Res Treat 72:227\u2013232","journal-title":"Breast Can Res Treat"},{"key":"9219_CR6","doi-asserted-by":"crossref","first-page":"2376","DOI":"10.1093\/emboj\/16.9.2376","volume":"16","author":"M Bedford","year":"1997","unstructured":"Bedford M, Chan D, Leder P (1997) FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands. EMBO J 16:2376\u20132383","journal-title":"EMBO J"},{"key":"9219_CR7","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","volume":"57","author":"Y Benjamini","year":"1995","unstructured":"Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J Royal Stat Soc Series B 57:289\u2013300","journal-title":"J Royal Stat Soc Series B"},{"key":"9219_CR8","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S0302-2838(02)00020-9","volume":"41","author":"I Bieche","year":"2003","unstructured":"Bieche I, Latil A, Parfait B, Vidaud D, Laurendeau I, Lidereau R, Cussenot O, Vidaud M (2003) CGA gene (coding for the alpha subunit of glycoprotein hormones) overexpression in ER a-positive prostate tumors. Eur Urol 41:335\u2013341","journal-title":"Eur Urol"},{"key":"9219_CR9","doi-asserted-by":"crossref","first-page":"6955","DOI":"10.1038\/sj.onc.1204739","volume":"20","author":"I Bieche","year":"2001","unstructured":"Bieche I, Parfait B, Nogues C, Andrieu C, Vidaud D, Spyratos F, Lidereau R, Vidaud M (2001) The CGA gene as new predictor of the response to endocrine therapy in ER a-positive postmenopausal breast cancer patients. Oncogene 20:6955\u20136959","journal-title":"Oncogene"},{"key":"9219_CR10","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/S0955-0674(98)80042-2","volume":"10","author":"R Black","year":"1998","unstructured":"Black R, White J (1998) ADAMs: focus on the protease domain. Curr Opin Cell Biol 10:654\u2013659","journal-title":"Curr Opin Cell Biol"},{"key":"9219_CR11","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1093\/bioinformatics\/19.2.185","volume":"19","author":"BM Bolstad","year":"2003","unstructured":"Bolstad BM, Irizarry RA, Astrand M, Speed TP (2003) A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics 19:185\u2013193","journal-title":"Bioinformatics"},{"key":"9219_CR12","first-page":"2849","volume":"4","author":"P Bunn","year":"1998","unstructured":"Bunn P, Helfrich B, Brenner D, Chan D, Dykes D, Cohen A, Miller Y (1998) Effects of recombinant neutral endopeptidase (EC 3.4.24.11) on the growth of lung cancer cell lines in vitro and in vivo. Clin Cancer Res 4:2849\u20132858","journal-title":"Clin Cancer Res"},{"key":"9219_CR13","doi-asserted-by":"crossref","first-page":"659","DOI":"10.2174\/1566524033479447","volume":"3","author":"R Cairns","year":"2003","unstructured":"Cairns R, Khokha R, Hill R (2003) Molecular mechanisms of tumor invasion and metastasis: an integrated view. Curr Mol Med 3:659\u2013671","journal-title":"Curr Mol Med"},{"key":"9219_CR14","doi-asserted-by":"crossref","first-page":"39572","DOI":"10.1074\/jbc.M308179200","volume":"278","author":"Y Chen","year":"2003","unstructured":"Chen Y, Layne M, Chung S, Ejima K, Baron R, Yet S, Perrella M (2003) Elk-3 is a transcriptional repressor of nitric-oxide synthase 2. J Biol Chem 278:39572\u201339577","journal-title":"J Biol Chem"},{"key":"9219_CR15","first-page":"F1","volume":"1377","author":"J Dittmer","year":"1998","unstructured":"Dittmer J, Nordheim A (1998) Ets transcription facotrs and human disease. BiochimBiophysActa 1377:F1\u201311","journal-title":"BiochimBiophysActa"},{"key":"9219_CR16","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s10549-004-3269-5","volume":"90","author":"D Drubin","year":"2005","unstructured":"Drubin D, Smith JS, Liu W, Zhao W, Chase G, Clawson G (2005) Comparison of cryopreservation and standard needle biopsy for gene expression profiling of human breast cancer specimens. Breast Can Res Treat 90:93\u201396","journal-title":"Breast Can Res Treat"},{"key":"9219_CR17","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1111\/j.1365-2133.2004.06350.x","volume":"152","author":"S Edmondson","year":"2005","unstructured":"Edmondson S, Thumiger S, Kaur P, Loh B, Loelmeyer R, Li A, Silha J, Murphy J, Werther G (2005) Insulin-like growth factor\u2423binding protein-3 (IGFBP-3) localiozes to and modulates epidermal keratinocytes in vivo. Br J Dermatol 152:225\u2013230","journal-title":"Br J Dermatol"},{"key":"9219_CR18","first-page":"1003","volume":"24","author":"N Erin","year":"2004","unstructured":"Erin N, Boyer P, Bonneau R, Clawson G, Welch D (2004) Capsaicin-mediated denervation of sensory neurons promotes mammary tumor metastasis to lung and heart. Anticancer Res 24:1003\u20131009","journal-title":"Anticancer Res"},{"key":"9219_CR19","doi-asserted-by":"crossref","first-page":"232","DOI":"10.2144\/04372ST04","volume":"37","author":"N Erin","year":"2004","unstructured":"Erin N, Clawson G (2004) Parameters affecting substance P measurement inheart, lung, and skin. BioTechiques 37:232\u2013236","journal-title":"BioTechiques"},{"key":"9219_CR20","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/S0306-4522(02)00934-X","volume":"117","author":"N Erin","year":"2003","unstructured":"Erin N, Lehman R, Boyer P, Billingsley M (2003) In vitro hypoxia and excitotoxicity in human brain induces calcineurin-Bcl-2 interactions. Neuroscience 117:557\u2013565","journal-title":"Neuroscience"},{"key":"9219_CR21","doi-asserted-by":"crossref","first-page":"13233","DOI":"10.1073\/pnas.93.23.13233","volume":"93","author":"D Fambrough","year":"1996","unstructured":"Fambrough D, Pan D, Rubin G, Goodman C (1996) The cell surface metalloprotease\/disintegrin Kuzbanian is required for axonal extension in Drosophila. Proc Natl Acad Sci(USA) 93:13233\u201313238","journal-title":"Proc Natl Acad Sci(USA)"},{"key":"9219_CR22","doi-asserted-by":"crossref","first-page":"18871","DOI":"10.1074\/jbc.273.30.18871","volume":"273","author":"G Foos","year":"1998","unstructured":"Foos G, Garcia-Ramirez J, Galang C, Hauser C (1998) Elevated expression of Ets2 or distinct portions of Ets2 can reverse Ras-mediated cellular transformation. J Biol Chem 273:18871\u201318880","journal-title":"J Biol Chem"},{"key":"9219_CR23","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1097\/01.LAB.0000067499.57309.F6","volume":"83","author":"H Friess","year":"2003","unstructured":"Friess H, Zhu Z, Liard V, Shi X, Shrikhande S, Wang L, Lieb K, Korc M, Palma C, Zimmermann A, Reubi J, Buchler M (2003) Neurokinin-1 receptor expression and its potential effects on tumor growth in human pancreatic cancer. Lab Invest 83:731\u2013742","journal-title":"Lab Invest"},{"key":"9219_CR24","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1242\/dev.126.8.1781","volume":"126","author":"S Granderath","year":"1999","unstructured":"Granderath S, Stollewerk A, Greig S, Goodman C, O\u2019Kane C, Klambt C (1999) Loco encodes an RGS protein required for Drosophila glial differentiation. Development 126:1781\u20131791","journal-title":"Development"},{"key":"9219_CR25","doi-asserted-by":"crossref","first-page":"31","DOI":"10.2174\/1389203033380313","volume":"4","author":"M Hallberg","year":"2003","unstructured":"Hallberg M, Nyberg F (2003) Neuropeptide conversion to bioactive fragments \u2013an important pathway in neuromodulation. Curr Protein Pept Sci 4:31\u201344","journal-title":"Curr Protein Pept Sci"},{"key":"9219_CR26","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/1471-2407-5-9","volume":"5","author":"T Hanafusa","year":"2005","unstructured":"Hanafusa T, Shinji T, Shiranha H, Nouso K, Iwasaki Y, Yumoto J, Ono T, Koide N (2005) Functional promoter upstream p53 regulatory sequence of IGFBP3 that is silenced by specific methylation. BMC Cancer 5:9\u201315","journal-title":"BMC Cancer"},{"key":"9219_CR27","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0092-8674(00)81683-9","volume":"100","author":"D Hanahan","year":"2000","unstructured":"Hanahan D, Weinberg R (2000) The hallmarks of cancer. Cell 100:57\u201370","journal-title":"Cell"},{"key":"9219_CR28","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1038\/sj.onc.1204183","volume":"20","author":"L Heasley","year":"2001","unstructured":"Heasley L (2001) Autocrine and paracine signaling through neuropeptide receptors in human cancer. Oncogene 20:1563\u20131569","journal-title":"Oncogene"},{"key":"9219_CR29","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1101\/gad.955102","volume":"16","author":"T Hirano","year":"2002","unstructured":"Hirano T (2002) The ABCs of SMC proteins: two-armed ATPases for chromosome condensation, col, and repair. Genes Develop 16:399\u2013414","journal-title":"Genes Develop"},{"key":"9219_CR30","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.cellsig.2004.10.007","volume":"17","author":"W Ho","year":"2005","unstructured":"Ho W, Xie Z, Zhao Z, Exton J (2005) Tyrosine phosphorylation of phospholipase D1 by v-Src does not per se result in activation. Cell Signal 17:691\u2013699","journal-title":"Cell Signal"},{"key":"9219_CR31","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1038\/nm0295-149","volume":"1","author":"L Holmgren","year":"1995","unstructured":"Holmgren L, O\u2019Reilly M, Folkman J (1995) Dormancy of micrometastases: balanced proliferation and apoptosis in the presence of angiogenesis suppression. Nature Med 1:149\u2013153","journal-title":"Nature Med"},{"key":"9219_CR32","doi-asserted-by":"crossref","first-page":"3364","DOI":"10.1523\/JNEUROSCI.14-05-03364.1994","volume":"14","author":"C Hornfeldt","year":"1994","unstructured":"Hornfeldt C, Sun X, Larson A. (1994) The NH2-terminus of substance P modulates NMDA-induced activity in the mouse spinal cord. J Neurosci 14:3364\u20133369","journal-title":"J Neurosci"},{"key":"9219_CR33","first-page":"160","volume":"69","author":"T Ikeda","year":"1999","unstructured":"Ikeda T, Ikeda K, Sasaki K, Kawakami K, Takahara J (1999) The inv(11)(p15q22) chromosome translocationof therapy-related myelodysplasia results in NUP98-DDX10 and DDX10-NUP98 fusion transcripts. Int J Hematol 69:160\u2013164","journal-title":"Int J Hematol"},{"key":"9219_CR34","unstructured":"Irizarry R, Gautier L, Cope LM (2003) The analysis of Gene Expression Data: Methods and software. Springer-Verlag"},{"key":"9219_CR35","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1093\/biostatistics\/4.2.249","volume":"4","author":"RA Irizarry","year":"2003b","unstructured":"Irizarry RA, Hobbs B, Collin F, Beazer-Barclay YD, Antonellis KJ, Scherf U, Speed TP (2003b) Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4:249\u2013264","journal-title":"Biostatistics"},{"key":"9219_CR36","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1523\/JNEUROSCI.4792-03.2004","volume":"24","author":"N Iwata","year":"2004","unstructured":"Iwata N, Mizukami H, Shirotani K, Takaki Y, Muramatsu S, Lu B, Gerard N, Ozawa K, Saido T (2004) Presynapticlocalization of neprilysin contributes to efficient clearance of amyloid-beta peptide in mouse brain. J Neurosci 24:991\u2013998","journal-title":"J Neurosci"},{"key":"9219_CR37","doi-asserted-by":"crossref","first-page":"147","DOI":"10.3109\/10425170109080769","volume":"12","author":"D Jones","year":"2001","unstructured":"Jones D, Mattei M, Horsley D, Crowell I, Singh P (2001) The\u2423gene and pseudogenes of Cbx3\/mHP1 gamma. DNA Seq 12:147\u2013160","journal-title":"DNA Seq"},{"key":"9219_CR38","first-page":"473","volume":"13","author":"M Katoh","year":"2004","unstructured":"Katoh M, Katoh M (2004) Identification and characterization of human DIAPH3 gene in silico. Int J Mol Med 13:473\u2013478","journal-title":"Int J Mol Med"},{"key":"9219_CR39","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1074\/jbc.M306277200","volume":"279","author":"N Korfali","year":"2004","unstructured":"Korfali N, Ruchaud S, Loegering D, Bernard D, Dingwall C, Kaufmann S, Earnshaw W (2004) Caspase-7 gene disruption reveals an involvement of the enzyme during the early stages of apoptosis. J Biol Chem 279:1030\u20131039","journal-title":"J Biol Chem"},{"key":"9219_CR40","first-page":"1272","volume":"61","author":"A Kruger","year":"2001","unstructured":"Kruger A, Soeltl R, Sopov I, Kopitz C, Arlt M, Magdolen V, Harbeck N, Gansbacher B, Schmitt M (2001) Hydroxamate-type matrix metalloproteinase inhibitor batimastat promotes liver metastasis. Cancer Res 61:1272\u20131275","journal-title":"Cancer Res"},{"key":"9219_CR41","first-page":"33","volume":"6","author":"H Kurokawa","year":"1999","unstructured":"Kurokawa H, Nishio K, Fukumoto H, Tomonari A, Suzuki T, Saijo N (1999) Alteration of caspase-3 (CPP32\/Yama\/apopain) in wild-type MCF-7, breast cancer cells. Oncol Rpts 6:33\u201337","journal-title":"Oncol Rpts"},{"key":"9219_CR42","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1002\/pd.1029","volume":"25","author":"J Laigaard","year":"2005","unstructured":"Laigaard J, Christiansen M, Frohlich C, Pedersen B, Ottesen B, Wewer U (2005) The level of ADAM12-S in maternal serum is an early first-trimester marker of fetal trisomy 18. Prenat Diagn 25:45\u201346","journal-title":"Prenat Diagn"},{"key":"9219_CR43","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/ijc.20410","volume":"112","author":"K Lang","year":"2004","unstructured":"Lang K, Drell T, Lindecke A, Niggemann B, Kaltschmidt C, Zaenker K, Entschladen F (2004) Induction of a metastatogenic tumor cell type by neurotransmitters and its pharmacological inhibition by established drugs. Int J Cancer 112:231\u2013238","journal-title":"Int J Cancer"},{"key":"9219_CR44","first-page":"5477","volume":"9","author":"A Latil","year":"2003","unstructured":"Latil A, Bieche I, Chene L, Laurendeau I, Berthon P, Cussenot O, Vidaud M (2003) Gene expression profiling in clinically localized prostate cancer: a four-gene expression model predicts clinical behavior. Clin Cancer Res 9:5477\u20135485","journal-title":"Clin Cancer Res"},{"key":"9219_CR45","doi-asserted-by":"crossref","unstructured":"Lelekakis M, Moseley J, Martin T, et al (1999) A novel orthotopic model of breast cancer metastasis to bone. Clin Exptl Metastasis 17:163\u2013170","DOI":"10.1023\/A:1006689719505"},{"key":"9219_CR46","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1007\/s00432-004-0619-y","volume":"131","author":"U Lendeckel","year":"2005","unstructured":"Lendeckel U, Kohl J, Arndt M, Carl-McGrath S, Donat H, Rocken C (2005) Increased expression of ADAM family members in human breast cancer and breast cancer cell lines. J Cancer Res Clin Oncol 131:42\u201348","journal-title":"J Cancer Res Clin Oncol"},{"key":"9219_CR47","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1073\/pnas.98.1.31","volume":"98","author":"C Li","year":"2001","unstructured":"Li C, Wong WH (2001) Model-based analysis of oligonucleotide arrays: expression index cmoputation and outlier detection. Proc Natl Acad Sci(USA) 98:31\u201336","journal-title":"Proc Natl Acad Sci(USA)"},{"key":"9219_CR48","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1074\/jbc.271.4.1825","volume":"271","author":"J Lippke","year":"1996","unstructured":"Lippke J, Gu Y, Sarnecki C, Caron P, Su M (1996) Identification and characterization of CPP32\/Mch2 homolog 1, a novel cysteine protease similar to CPP32. J Biol Chem 271:1825\u20131828","journal-title":"J Biol Chem"},{"key":"9219_CR49","doi-asserted-by":"crossref","first-page":"28082","DOI":"10.1074\/jbc.M009772200","volume":"276","author":"A MacKinnon","year":"2001","unstructured":"MacKinnon A, Waters C, Jodrell D, Haslett C, Sethi T (2001) Bombesin and substance P analogues differentially regulate G-protein coupling to the bombesin receptor. Direct evidence for biased agonism. J Biol Chem 276:28082\u201328091","journal-title":"J Biol Chem"},{"key":"9219_CR50","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1186\/gb-2003-4-7-223","volume":"4","author":"D Mangus","year":"2003","unstructured":"Mangus D, Evans M, Jacobson A (2003) Poly(A)-binding proteins: multifunctional scaffolds for the post-transcriptional control of gene expression. Genome Biol 4:223 (Epub.)","journal-title":"Genome Biol"},{"key":"9219_CR51","doi-asserted-by":"crossref","first-page":"3408","DOI":"10.1073\/pnas.95.7.3408","volume":"95","author":"K Maskos","year":"1998","unstructured":"Maskos K, Fernandez-Catalan C, Huber R, Bourenkov G, Bartunik H, Ellestad G, Reddy P, Wolfson M, Ruach C, Castner B, Davis R, Clarke H, Petersen M, Fitzner J, Cerretti D, March c, Paxton R, Balck R, Bode W (1998) Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme. Proc Natl Acad Sci(USA) 95:3408\u20133412","journal-title":"Proc Natl Acad Sci(USA)"},{"key":"9219_CR52","first-page":"1781","volume":"25","author":"G Mazzocchi","year":"2004","unstructured":"Mazzocchi G, Malendowicz L, Ziolkowska A, Spinazzi R, Rebuffat P, Aragona F, Ferrazzi E, Parnigotto P, Nussdorfer G (2004) Adrneomedullin (AM) and AM receptor type 2 expression is up-regulated in prostate carcinomas (PC), and AM stimulates in vitro growth of a PC-derived cell line by enhancing proliferation and decreasing apoptosis rates. Int J Oncol 25:1781\u20131787","journal-title":"Int J Oncol"},{"key":"9219_CR53","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1158\/1078-0432.CCR-0846-3","volume":"10","author":"D McCulloch","year":"2004","unstructured":"McCulloch D, Akl P, Samaratunga H, Herington A, Odorico D (2004) Expression of the disintegrin metalloprotease, ADAM-10,\u2423in prostate cancer and its regulation by dihydrotestosterone, insulin-like growth factor 1, and epidermal growth factor in the\u2423prostate cancer cell model LNCaP. Clin Cancer Res 10: 314\u2013323","journal-title":"Clin Cancer Res"},{"key":"9219_CR54","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1002\/ar.a.20087","volume":"280A","author":"R McCuskey","year":"2004","unstructured":"McCuskey R (2004) Anatomy of efferent hepatic nerves. Anat Rec A Discov Mol Cell Evol Biol 280A:821\u2013826","journal-title":"Anat Rec A Discov Mol Cell Evol Biol"},{"key":"9219_CR55","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0167-0115(99)00089-0","volume":"85","author":"R Mentlein","year":"1999","unstructured":"Mentlein R (1999) Dipeptidyl-peptidase IV (CD26)\u2013role in the inactivation of regulatory peptides. Regul Pept 85:9\u201324","journal-title":"Regul Pept"},{"key":"9219_CR56","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1111\/j.1440-1746.2004.03764.x","volume":"20","author":"S Mizuguchi","year":"2005","unstructured":"Mizuguchi S, Ohno T, Hattori Y, Kamata K, Arai K, Saeki T, Saigenji K, Hayashi I, Kuribayashi Y, Majima M (2005) Calcitonin gene-related peptide released by capsaicin suppresses myoelectrical activity of gastric smooth muscle. J Gastroenterol Hepatol 20:611\u2013618","journal-title":"J Gastroenterol Hepatol"},{"key":"9219_CR57","first-page":"4242","volume":"59","author":"N Neznanov","year":"1999","unstructured":"Neznanov N, Man A, Yamamoto H, Hauser C, Cardiff R, Oshima R (1999) A single targeted Ets2 allele restricts development of mammary tumors in transgenic mice. Cancer Res 59:4242\u20134246","journal-title":"Cancer Res"},{"key":"9219_CR58","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1089\/dna.1996.15.855","volume":"15","author":"M Nozaki","year":"1996","unstructured":"Nozaki M, Onishi Y, Kanno N, Ono Y, Fujimura Y (1996) Molecular cloning of Elk-3, a new member of the Ets family expressed during mouse embryognesis and analysis of its transcriptional repression activity. DNA Cell Biol 15:855\u2013862","journal-title":"DNA Cell Biol"},{"key":"9219_CR59","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1359\/JBMR.041108","volume":"20","author":"S Offley","year":"2005","unstructured":"Offley S, Guo T, Wei t, Clark J, Vogel H, Lindsey D, Jacobs C, Yao W, Lane N, Kingery W (2005) Capsaicin-sensitive sensory neurons contribute to the maintenance of trabecular bone integrity. J Bone Miner Res 20:257\u2013267","journal-title":"J Bone Miner Res"},{"key":"9219_CR60","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1111\/j.1349-7006.2004.tb03320.x","volume":"95","author":"T Oikawa","year":"2004","unstructured":"Oikawa T (2004) ETS transcription factors: possible tragets for cancer therapy. Cancer Sci 95:626\u2013633","journal-title":"Cancer Sci"},{"key":"9219_CR61","doi-asserted-by":"crossref","first-page":"5437","DOI":"10.1073\/pnas.93.11.5437","volume":"93","author":"J Pai","year":"1996","unstructured":"Pai J, Brown M, Goldstein J (1996) Purification and cDNA cloning of a second apoptosis-related cysteine protease that cleaves and activates sterol regulatory element binding proteins. Proc Natl Acad Sci(USA) 93:5437\u20135442","journal-title":"Proc Natl Acad Sci(USA)"},{"key":"9219_CR62","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1054\/bjoc.1999.0946","volume":"82","author":"C Palma","year":"2000","unstructured":"Palma C, Bigioni M, Irrissuto C, Nardelli F, Maggi C, Manzini S (2000) Anti-tumor activity of tachykinin NK1 receptor antagonists on human glioma U373 MG xenografts. Br J Cancer 82:480\u2013487","journal-title":"Br J Cancer"},{"key":"9219_CR63","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1053\/hupa.2001.24328","volume":"32","author":"F Palmerini","year":"2001","unstructured":"Palmerini F, Devilard E, Jarry A, Birg F, Xerri L (2001) Caspase 7 downregulation as an immunohistochemical marker of colonic carcinoma. Hum Pathol 32:461\u2013467","journal-title":"Hum Pathol"},{"key":"9219_CR64","first-page":"123","volume":"24","author":"S Park","year":"2004","unstructured":"Park S, Wu C, Safa A (2004) A P-glycoprotein- and MRP1-independent doxorubicin-resistant variant of the MCF-7 breast cancer cell line with defects in caspase-6, -7, and -10 activation pathways. Anticancer Res 24:123\u2013131","journal-title":"Anticancer Res"},{"key":"9219_CR65","doi-asserted-by":"crossref","first-page":"3860","DOI":"10.1063\/1.1286308","volume":"71","author":"RVP Patois","year":"2000","unstructured":"Patois RVP, Cretin B (2000) Near field acoustic densimeter and viscosimeter. Rev Sci Instrum 71:3860","journal-title":"Rev Sci Instrum"},{"key":"9219_CR66","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0014-5793(96)00474-7","volume":"387","author":"M Perez","year":"1996","unstructured":"Perez M, Rompato G, Corbi N, DeGregorio L, Dragani T, Passananti C (1996) Zpf60, a mouse zinc finger gene expressed transiently during in vitro muscle differentiation. FEBS Lett 387:117\u2013121","journal-title":"FEBS Lett"},{"key":"9219_CR67","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1172\/JCI20864","volume":"113","author":"R Postina","year":"2004","unstructured":"Postina R, Schroeder A, Dewachter I, Bohl J, Schmitt U, Kojro E, Prinzen C, Endres K, Hiemke C, Blessing M, Flamez P, Dequenne A, Godeau E, van Leuven F, Fahrenholz F (2004) A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model. J Clin Invest 113:1456\u20131464","journal-title":"J Clin Invest"},{"key":"9219_CR68","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1016\/S0002-9440(10)64779-7","volume":"157","author":"J Reed","year":"2000","unstructured":"Reed J (2000) Mechanisms of apoptosis. Am J Pathol 157:1415\u20131430","journal-title":"Am J Pathol"},{"key":"9219_CR69","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1126\/science.273.5279.1227","volume":"273","author":"J Rooke","year":"1996","unstructured":"Rooke J, Pan D, Xu T, Rubin G (1996) KUZ, a conserved metalloprotease-disintegrin protein with two roles in Drosophila neurogenesis. Science 273:1227\u20131231","journal-title":"Science"},{"key":"9219_CR70","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1016\/S0196-9781(98)00116-8","volume":"19","author":"R Rosati","year":"1998","unstructured":"Rosati R, Adil M, Ali M, Eliason J, Orosz A, Sebestyen F, Kalemkerian G (1998) Induction of apoptosis by a short-chain neuropeptide analog in small cell lung cancer. Peptides 19:1519\u20131523","journal-title":"Peptides"},{"key":"9219_CR71","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1358\/mf.2004.26.3.809722","volume":"26","author":"C Sakurada","year":"2004","unstructured":"Sakurada C, Watanabe C, Sakurada T (2004) Occurrence of substance P(1\u20137) in the metabolism of substance P and its antinociceptive activity at the mouse spinal cord level. Meth Exp Clin Pharmacol 26:171\u2013176","journal-title":"Meth Exp Clin Pharmacol"},{"key":"9219_CR72","first-page":"1027","volume":"58","author":"E Sapi","year":"1998","unstructured":"Sapi E, Flick M, Rodov S, Kacinski B (1998) Ets-2 transdominant mutant abolishes anchorage=independent growth and macrophage colony-stimulating factor-stimulated invasion by BT20 breast carcinoma cells. Cancer Res 58:1027\u20131033","journal-title":"Cancer Res"},{"key":"9219_CR73","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1111\/j.2042-7158.1982.tb04245.x","volume":"34","author":"A Saria","year":"1982","unstructured":"Saria A, Skofitsch G, Lembeck F (1982) Distribution of capsaicin in rat tissues after systemic administration. J. Pharm Pharmacol 34:273\u2013275","journal-title":"J. Pharm Pharmacol"},{"key":"9219_CR74","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1006\/geno.1996.0184","volume":"33","author":"K Savitsky","year":"1996","unstructured":"Savitsky K, Ziv Y, Bar-Shira A, LGilad S, Tagle D, Smith S, \u2018Uziel T, Sfez S, Nahmias J, Sartiel A, Eddy R, Shows T, Rotman G (1996) A human gene (DDX10) encoding a putative DEAD-box RNA helicase at 11q22-q23. Genomics 33:199\u2013206","journal-title":"Genomics"},{"issue":"pt. 21","key":"9219_CR75","doi-asserted-by":"crossref","first-page":"3603","DOI":"10.1242\/jcs.112.21.3603","volume":"112","author":"J Schlondorff","year":"1999","unstructured":"Schlondorff J, Blobel C (1999) Metalloprotease-disintegrins: modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding. J Cell Sci 112(pt. 21):3603\u20133617","journal-title":"J Cell Sci"},{"key":"9219_CR76","first-page":"6579","volume":"62","author":"Y Seki","year":"2002","unstructured":"Seki Y, Suico M, Uto A, Hisatsure A, Shuto T, Isohama Y, Kai H (2002) The ETS transcription factor MEF is a candidate tumor suppressor gene on the X chromosome. Cancer Res 62:6579\u20136586","journal-title":"Cancer Res"},{"key":"9219_CR77","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1016\/S0015-0282(01)01996-3","volume":"76","author":"D Session","year":"2001","unstructured":"Session D, Lee G, Wolgemuth D (2001) Charactrerization of D1Pas1, a mouse autosomal homologue of the human AZFa represents a nuclear protein in spermatogenic cells. Fertil Steril 76:804\u2013811","journal-title":"Fertil Steril"},{"key":"9219_CR78","doi-asserted-by":"crossref","first-page":"4129","DOI":"10.1038\/sj.onc.1205527","volume":"21","author":"M Shin","year":"2002","unstructured":"Shin M, Kim H, Lee S, Lee J, Song Y, Kim Y, Park W, Kim S, Lee S, Park J, Lee J, Xiao W, Jo K, Wang Y, Lee K, Park Y, Kim S, Lee J, Yoo N (2002) Alterations of Fas-pathway genes associated with nodal metastasis in non-small cell lung cancer. Oncogene 21:4129\u20134136","journal-title":"Oncogene"},{"key":"9219_CR79","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.canlet.2004.07.020","volume":"216","author":"M Shindoh","year":"2004","unstructured":"Shindoh M, Higashino F, Kohgo T (2004) E1AF, an ets-oncogene family transcription factor. Cancer Lett 216:1\u20138","journal-title":"Cancer Lett"},{"key":"9219_CR80","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1073\/pnas.97.1.388","volume":"97","author":"D Singh","year":"2000","unstructured":"Singh D, Joshi D, Hameed M, Qian J, Gascon P, Maloof P, Mosenthal A, Rameshwar P (2000) Increased expression of preprotachykinin-I and neurokinin receptors in human breast cancer cells: implications for bone marrow metastasis. Proc Natl Acad Sci(USA) 97:388\u2013393","journal-title":"Proc Natl Acad Sci(USA)"},{"key":"9219_CR81","doi-asserted-by":"crossref","unstructured":"Skidgel R, Engelbrecht S, Johnson A, et al (1984) Hydrolysis of substance P and neurotensin by converting enzyme and neutral endopeptidase. Peptides 5:769","DOI":"10.1016\/0196-9781(84)90020-2"},{"key":"9219_CR82","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.peptides.2003.12.010","volume":"25","author":"R Skidgel","year":"2004","unstructured":"Skidgel R, Erdos E (2004) Angiotensin converting enzyme (ACE) and neprilysin hydrolyze neuropeptides: a brief history, the beginning and follow-ups to early studies. Peptides 25:521\u2013525","journal-title":"Peptides"},{"key":"9219_CR83","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1083\/jcb.144.2.281","volume":"144","author":"E Slee","year":"1999","unstructured":"Slee E, Harte M, Kluck R, Wolf B, Casiano C, Newmeyer D, Wang H, Reed J, Nicholson D, Alnemri E, Green D, Martin S (1999) Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9 dependent manner. J Cell Biol 144:281\u2013292","journal-title":"J Cell Biol"},{"key":"9219_CR84","doi-asserted-by":"crossref","first-page":"8048","DOI":"10.1038\/sj.onc.1206727","volume":"22","author":"Y Soung","year":"2003","unstructured":"Soung Y, Lee J, Kim H, Park W, Kim S, Lee J, Park J, Cho Y, Kim C, Park Y, Nam S, Jeong S, Kim S, Lee J, Yoo N, Lee S (2003) Inactivating mutations of CASPASE-7 gene in human cancers. Oncogene 22:8048\u20138052","journal-title":"Oncogene"},{"key":"9219_CR85","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0027-5107(02)00329-9","volume":"523\u2013524","author":"V Steele","year":"2003","unstructured":"Steele V, Hawk E, Viner J, Lubet R (2003) Mechanisms and applications of non-steroidal anti-inflammatory drugs in the cheomprevention of cancer. Mutat Res 523\u2013524:137\u2013144","journal-title":"Mutat Res"},{"key":"9219_CR86","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1023\/A:1006632819086","volume":"17","author":"M Takasu","year":"1999","unstructured":"Takasu M, Tada Y, Wang J, Tagawa M, Takenaga K (1999) Resistance to apoptosis induced by microenvironmental srtresses is correlated with metastatic potential in Lewis lung carcinoma. Clin Exp Metastasis 17:409\u2013416","journal-title":"Clin Exp Metastasis"},{"key":"9219_CR87","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1093\/jnen\/63.3.210","volume":"63","author":"L Tatenhorst","year":"2004","unstructured":"Tatenhorst L, Senner V, Puttmann S, Paulus W (2004) Regulators of G-protein signaling 3 and 4 (RGS3, RGS4) are associated with glioma invasion and motility. Neuropathol Exp Neurol 63:210\u2013222","journal-title":"Neuropathol Exp Neurol"},{"key":"9219_CR88","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1091\/mbc.12.6.1583","volume":"12","author":"E Taylor","year":"2001","unstructured":"Taylor E, Moghraby J, Lees J, Smit B, Moens P, Lehmann A (2001) Characterization of a novel human SMC heterodimer homologous to the S. pombe Rad18\/Spr18 complex. Mol Biol Cell 12:1583\u20131594","journal-title":"Mol Biol Cell"},{"key":"9219_CR89","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1007\/BF02919543","volume":"49","author":"T Tokuhara","year":"2001","unstructured":"Tokuhara T, Adachi M, Hashida H, Ishida H, Taki T, Higashiyama M, Kodama K, Tachibana S, Sasaki S, Miyake M (2001) Neutral endopeptidase\/CD10 and aminopeptidase N\/CD13 gene expression as a prognostic factor in non-small cell lung cancer. Jpn J Thorac Cardiovasc Surg 49:489\u2013496","journal-title":"Jpn J Thorac Cardiovasc Surg"},{"key":"9219_CR90","doi-asserted-by":"crossref","first-page":"5116","DOI":"10.1073\/pnas.091062498","volume":"98","author":"VG Tusher","year":"2001","unstructured":"Tusher VG, Tibshirani R, Chu G (2001) Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci(USA) 98:5116\u20135121","journal-title":"Proc Natl Acad Sci(USA)"},{"key":"9219_CR91","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1007\/BF02272149","volume":"28","author":"D Walsh","year":"1996","unstructured":"Walsh D, Hu d, Mapp P, Polak J, Blake D, Fan T (1996) Innervation and neurokinin receptors during angiogenesis in the rat sponge granuloma. Histochemical J 28:759\u2013769","journal-title":"Histochemical J"},{"key":"9219_CR92","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/j.1432-1033.1993.tb19864.x","volume":"211","author":"B Wasylyk","year":"1993","unstructured":"Wasylyk B, Hahn S, Giovane A (1993) The Ets family of transcription factors. Eur J Biochem 211:7\u201318","journal-title":"Eur J Biochem"},{"key":"9219_CR93","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1084\/jem.190.3.311","volume":"190","author":"U Wesley","year":"1999","unstructured":"Wesley U, Albino A, Tiwari S, Houghton A (1999) A role for dipeptidyl peptidase IV in suppressing the malignant phenotype of melaoncytic cells. J Exp Med 190:311\u2013322","journal-title":"J Exp Med"},{"key":"9219_CR94","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1191\/1352458505ms1123oa","volume":"11","author":"N Wilczak","year":"2005","unstructured":"Wilczak N, Ramsaransing g, Mostert J, Chesik D, De Keyser J (2005) Serum levels of insulin-like growth factor-1 and insulin-like growth factor binding protein 3 in relapsing and primary progressive multiple sclerosis. Mult Schler 11:13\u201315","journal-title":"Mult Schler"},{"key":"9219_CR95","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.cancergencyto.2004.06.014","volume":"157","author":"M Yamamoto","year":"2005","unstructured":"Yamamoto M, Kakihana K, Kurosu T, Murakami N, Miura O (2005) Clonal evolution with inv(11)(p15q22) and NUP98\/DDX10 fusion gene in imatinib-resistant chronic myelogenous leukemia. Cancer Genet Cytogenet 157:104\u2013108","journal-title":"Cancer Genet Cytogenet"},{"key":"9219_CR96","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1016\/j.bbrc.2005.02.087","volume":"329","author":"M Yoon","year":"2005","unstructured":"Yoon M, Yon C, Park S, Oh D, Han A, Kim D, Han J (2005) Role of phospholipaseD1 in neurite outgrowth in neural stem cells. Biochem Biophys Res Commun 329:804\u2013811","journal-title":"Biochem Biophys Res Commun"},{"key":"9219_CR97","doi-asserted-by":"crossref","first-page":"229","DOI":"10.2165\/00002512-199711030-00006","volume":"11","author":"A Yu","year":"1997","unstructured":"Yu A, Hewitt R, Connor E, Stetler-Stevenson W (1997) Matrix metalloproteinases. NOvel targets for directed cancer therapy. Drugs Aging 11:229\u2013244","journal-title":"Drugs Aging"},{"key":"9219_CR98","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0304-3940(94)90315-8","volume":"178","author":"R Yukhananov","year":"1994","unstructured":"Yukhananov R, Larson A (1994) An N-terminal fragment of substance P, substance P(1\u20137), down-regulates neurokinin-1 binding in the mouse spinal cord. Neurosci Lett 178:163\u2013166","journal-title":"Neurosci Lett"},{"key":"9219_CR99","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1038\/sj.cdd.4400593","volume":"6","author":"T Zheng","year":"1999","unstructured":"Zheng T, Hunot S, Kuida K, Flavell R (1999) Caspase knockouts: matters of life and death. Cell Death Differ 6:1043\u20131053","journal-title":"Cell Death Differ"}],"container-title":["Breast Cancer Research and Treatment"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-006-9219-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10549-006-9219-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-006-9219-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T05:53:35Z","timestamp":1736315615000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10549-006-9219-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,4,1]]},"references-count":99,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,10]]}},"alternative-id":["9219"],"URL":"https:\/\/doi.org\/10.1007\/s10549-006-9219-7","relation":{},"ISSN":["0167-6806","1573-7217"],"issn-type":[{"value":"0167-6806","type":"print"},{"value":"1573-7217","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,4,1]]}}}