{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T05:27:28Z","timestamp":1791091648854,"version":"4.1.0"},"reference-count":58,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2010,6,23]],"date-time":"2010-06-23T00:00:00Z","timestamp":1277251200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Breast Cancer Res Treat"],"published-print":{"date-parts":[[2010,8]]},"DOI":"10.1007\/s10549-010-0996-7","type":"journal-article","created":{"date-parts":[[2010,6,22]],"date-time":"2010-06-22T06:17:05Z","timestamp":1277187425000},"page":"803-811","source":"Crossref","is-referenced-by-count":72,"title":["Pharmacological interventions for fertility preservation during chemotherapy: a systematic review and meta-analysis"],"prefix":"10.1007","volume":"122","author":[{"given":"Irit","family":"Ben-Aharon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anat","family":"Gafter-Gvili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonard","family":"Leibovici","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salomon M.","family":"Stemmer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,6,23]]},"reference":[{"key":"996_CR1","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1634\/theoncologist.11-2-96","volume":"11","author":"MT Knobf","year":"2006","unstructured":"Knobf MT (2006) The influence of endocrine effects of adjuvant therapy on quality of life outcomes in younger breast cancer survivors. Oncologist 11:96\u2013110","journal-title":"Oncologist"},{"key":"996_CR2","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1080\/10428190500353877","volume":"47","author":"A Elis","year":"2006","unstructured":"Elis A, Tevet A, Yerushalmi R et al (2006) Fertility status among women treated for aggressive non-Hodgkin\u2019s lymphoma. Leuk Lymphoma 47:623\u2013627","journal-title":"Leuk Lymphoma"},{"key":"996_CR3","doi-asserted-by":"crossref","first-page":"5155","DOI":"10.1200\/JCO.2005.07.773","volume":"23","author":"B Thewes","year":"2005","unstructured":"Thewes B, Meiser B, Taylor A et al (2005) Fertility- and menopause-related information needs of younger women with a diagnosis of early breast cancer. J Clin Oncol 23:5155\u20135165","journal-title":"J Clin Oncol"},{"key":"996_CR4","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1634\/theoncologist.2008-0053","volume":"13","author":"M Sonmezer","year":"2008","unstructured":"Sonmezer M, Bang H, Oktay K (2008) GnRH analogues preserve gonadal function without preserving fertility? Oncologist 13:615\u2013617","journal-title":"Oncologist"},{"key":"996_CR5","doi-asserted-by":"crossref","first-page":"2917","DOI":"10.1200\/JCO.2006.06.5888","volume":"24","author":"SJ Lee","year":"2006","unstructured":"Lee SJ, Schover LR, Partridge AH, Patrizio P, Wallace WH, Hagerty K, Beck LN, Brennan LV, Oktay K, American Society of Clinical Oncology (2006) American Society of Clinical Oncology recommendations on fertility preservation in cancer patients. J Clin Oncol 24:2917\u20132931","journal-title":"J Clin Oncol"},{"key":"996_CR6","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/BF00254570","volume":"19","author":"JH Waxman","year":"1987","unstructured":"Waxman JH, Ahmed R, Smith D et al (1987) Failure to preserve fertility in patients with Hodgkin\u2019s disease. Cancer Chemother Pharmacol 19:159\u2013162","journal-title":"Cancer Chemother Pharmacol"},{"key":"996_CR7","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1093\/oxfordjournals.humrep.a019457","volume":"11","author":"Z Blumenfeld","year":"1998","unstructured":"Blumenfeld Z, Avivi I, Linn S et al (1998) Prevention of irreversible chemotherapy-induced ovarian damage in young women with lymphoma by a gonadotropin-releasing hormone agonist in parallel to chemotherapy. Hum Reprod 11:1620\u20131626","journal-title":"Hum Reprod"},{"key":"996_CR8","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1191\/096120300678828596","volume":"9","author":"Z Blumenfeld","year":"2000","unstructured":"Blumenfeld Z, Shapiro D, Shteinberg M et al (2000) Preservation of fertility and ovarian function and minimizing gonadotoxicity in young women with systemic lupus erythematosus treated by chemotherapy. Lupus 9:401\u2013405","journal-title":"Lupus"},{"key":"996_CR9","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1006\/gyno.2001.6181","volume":"81","author":"B Pereyra Pacheco","year":"2001","unstructured":"Pereyra Pacheco B, Mendez Ribas JM, Milone G et al (2001) Use of GnRH analogs for functional protection of the ovary and preservation of fertility during cancer treatment in adolescents: a preliminary report. Gynecol Oncol 81:391\u2013397","journal-title":"Gynecol Oncol"},{"issue":"Suppl 9","key":"996_CR10","first-page":"408","volume":"50","author":"M Petri","year":"2004","unstructured":"Petri M, Brodsky R, Jones R et al (2004) High dose cyclophosphamide can cause ovarian failure. Arthritis Rheum 50(Suppl 9):408","journal-title":"Arthritis Rheum"},{"key":"996_CR11","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1093\/jncimonographs\/lgi015","volume":"34","author":"Z Blumenfeld","year":"2005","unstructured":"Blumenfeld Z, Eckman A (2005) Preservation of fertility and ovarian function and minimization of chemotherapy-induced gonadotoxicity in young women by GnRH-a. J Natl Cancer Inst Monogr 34:40\u201343","journal-title":"J Natl Cancer Inst Monogr"},{"key":"996_CR12","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1093\/humrep\/dei018","volume":"20","author":"EJ Dann","year":"2005","unstructured":"Dann EJ, Epelbaum R, Avivi I et al (2005) Fertility and ovarian function are preserved in women treated with an intensified regimen of cyclophosphamide, adriamycin, vincristine and prednisone (Mega-CHOP) for non-Hodgkin lymphoma. Hum Reprod 20:2247\u20132249","journal-title":"Hum Reprod"},{"key":"996_CR13","doi-asserted-by":"crossref","first-page":"2761","DOI":"10.1002\/art.21263","volume":"52","author":"EC Somers","year":"2005","unstructured":"Somers EC, Marder W, Christman GM et al (2005) Use of a gonadotropin-releasing hormone analog for protection against premature ovarian failure during cyclophosphamide therapy in women with severe lupus. Arthritis Rheum 52:2761\u20132767","journal-title":"Arthritis Rheum"},{"key":"996_CR14","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/j.fertnstert.2006.10.004","volume":"87","author":"C Castelo-Branco","year":"2007","unstructured":"Castelo-Branco C, Nomdedeu B, Camus A et al (2007) Use of gonadotropin releasing hormone agonists in patients with Hodgkin\u2019s disease for preservation of ovarian function and reduction of gonadotoxicity related to chemotherapy. Fertil Steril 87:703\u2013706","journal-title":"Fertil Steril"},{"key":"996_CR15","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1080\/10245330600954072","volume":"12","author":"L Giuseppe","year":"2007","unstructured":"Giuseppe L, Attilio G, Edoardo DN et al (2007) Ovarian function after cancer treatment in young women affected by Hodgkin disease (HD). Hematology 12:141\u2013147","journal-title":"Hematology"},{"key":"996_CR16","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1007\/s10815-008-9276-4","volume":"25","author":"F Azem","year":"2008","unstructured":"Azem F, Samara N, Cohen T et al (2008) Assessment of ovarian reserve following ovarian tissue banking and\/or GnRH-a co-treatment prior to chemotherapy in patients with Hodgkin\u2019s disease. J Assist Reprod Genet 25:535\u2013538","journal-title":"J Assist Reprod Genet"},{"key":"996_CR17","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.fertnstert.2007.02.010","volume":"89","author":"Z Blumenfeld","year":"2008","unstructured":"Blumenfeld Z, Avivi I, Eckman A et al (2008) Gonadotropin-releasing hormone agonist decreases chemotherapy induced gonadotoxicity and premature ovarian failure in young female patients with Hodgkin lymphoma. Fertil Steril 89:166\u2013173","journal-title":"Fertil Steril"},{"key":"996_CR18","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1053\/j.ajkd.2008.06.017","volume":"52","author":"A Cigni","year":"2008","unstructured":"Cigni A, Faedda R, Atzeni MM et al (2008) Hormonal strategies for fertility preservation in patients receiving cyclophosphamide to treat glomerulonephritis: a nonrandomized trial and review of the literature. Am J Kidney Dis 52:887\u2013896","journal-title":"Am J Kidney Dis"},{"key":"996_CR19","doi-asserted-by":"crossref","unstructured":"Ismail-Khan R, Minton S, Cox C et al (2008) Preservation of ovarian function in young women treated with neoadjuvant chemotherapy for breast cancer: a randomized trial using the GnRH agonist (triptorelin) during chemotherapy. J Clin Oncol 26:(abstr 524)","DOI":"10.1200\/jco.2008.26.15_suppl.524"},{"key":"996_CR20","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1093\/humrep\/den005","volume":"23","author":"M Huser","year":"2008","unstructured":"Huser M, Crha I, Ventruba P et al (2008) Prevention of ovarian function damage by a GnRH analogue during chemotherapy in Hodgkin lymphoma patients. Hum Reprod 23:863\u2013868","journal-title":"Hum Reprod"},{"key":"996_CR21","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/j.fertnstert.2007.12.044","volume":"91","author":"A Badawy","year":"2009","unstructured":"Badawy A, Elnashar A, El-Ashry M et al (2009) Gonadotropin-releasing hormone agonists for prevention of chemotherapy-induced ovarian damage: prospective randomized study. Fertil Steril 91:694\u2013697","journal-title":"Fertil Steril"},{"key":"996_CR22","doi-asserted-by":"crossref","unstructured":"Nitzschke M, Raddatz J,Bohlmann MK et al (2010) GnRH analogs do not protect ovaries from chemotherapy-induced ultrastructural injury in Hodgkin\u2019s lymphoma patients. Arch Gynecol Obstet 282(1):83\u201388","DOI":"10.1007\/s00404-009-1308-5"},{"key":"996_CR23","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1007\/s10549-009-0313-5","volume":"117","author":"A Sverrisdottir","year":"2009","unstructured":"Sverrisdottir A, Nystedt M, Johansson H et al (2009) Adjuvant goserelin and ovarian preservation in chemotherapy treated patients with early breast cancer: results from a randomized trial. Breast Cancer Res Treat 117:561\u2013567","journal-title":"Breast Cancer Res Treat"},{"key":"996_CR24","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1002\/1097-0142(19830915)52:6<988::AID-CNCR2820520610>3.0.CO;2-6","volume":"52","author":"E Whitehead","year":"1983","unstructured":"Whitehead E, Shalet SM, Blackledge G et al (1983) The effect of combination chemotherapy on ovarian function in women treated for Hodgkin\u2019s disease. Cancer 52:988\u2013993","journal-title":"Cancer"},{"key":"996_CR25","first-page":"151","volume":"10","author":"A Longhi","year":"2003","unstructured":"Longhi A, Pignotti E, Versari M et al (2003) Effect of oral contraceptive on ovarian function in young females undergoing neoadjuvant chemotherapy treatment for osteosarcoma. Oncol Rep 10:151\u2013155","journal-title":"Oncol Rep"},{"key":"996_CR26","doi-asserted-by":"crossref","first-page":"7555","DOI":"10.1200\/JCO.2005.08.138","volume":"23","author":"K Behringer","year":"2005","unstructured":"Behringer K, Breuer K, Reineke T et al (2005) Secondary amenorrhea after Hodgkin\u2019s lymphoma is influenced by age at treatment, stage of disease, chemotherapy regimen, and the use of oral contraceptives during therapy: a report from the German Hodgkin\u2019s Lymphoma Study Group. J Clin Oncol 23:7555\u20137564","journal-title":"J Clin Oncol"},{"key":"996_CR27","doi-asserted-by":"crossref","unstructured":"Behringer K, Wildt L, Mueller H et al (2010) No protection of the ovarian follicle pool with the use of GnRH-analogues or oral contraceptives in young women treated with escalated BEACOPP for advanced-stage Hodgkin lymphoma. Final results of a phase II trial from the German Hodgkin Study Group. Ann Oncol (in press)","DOI":"10.1093\/annonc\/mdq066"},{"key":"996_CR28","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1093\/annonc\/mdj029","volume":"17","author":"L Del Mastro","year":"2008","unstructured":"Del Mastro L, Catzeddu T, Boni L et al (2008) Prevention of chemotherapy-induced menopause by temporary ovarian suppression with goserelin in young, early breast cancer patients. Ann Oncol 17:74\u201378","journal-title":"Ann Oncol"},{"key":"996_CR29","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1080\/09513590400027414","volume":"20","author":"HR Franke","year":"2005","unstructured":"Franke HR, Smit WM, Vermes I (2005) Gonadal protection by a gonadotropin-releasing hormone agonist depot in young women with Hodgkin\u2019s disease undergoing chemotherapy. Gynecol Endocrinol 20:274\u2013278","journal-title":"Gynecol Endocrinol"},{"key":"996_CR30","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1080\/09513590701327661","volume":"23","author":"C Potolog-Nahari","year":"2007","unstructured":"Potolog-Nahari C, Fishman A, Cohen I (2007) Protection of ovarian function and fertility using a combination of gonadotropin-releasing hormone (GnRH) agonist and GnRH antagonist during cancer treatment in young females. Gynecol Endocrinol 23:290\u2013294","journal-title":"Gynecol Endocrinol"},{"key":"996_CR31","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1002\/cncr.21646","volume":"106","author":"F Recchia","year":"2006","unstructured":"Recchia F, Saggio G, Amiconi G et al (2006) Gonadotropin-releasing hormone analogues added to adjuvant chemotherapy protect ovarian function and improve clinical outcomes in young women with early breast carcinoma. Cancer 106:514\u2013523","journal-title":"Cancer"},{"key":"996_CR32","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1038\/sj.bmt.1701483","volume":"22","author":"C Teinturier","year":"1998","unstructured":"Teinturier C, Hartmann O, Valteau-Couanet D et al (1998) Ovarian function after autologous bone marrow transplantation in childhood: high-dose busulfan is a major cause of ovarian failure. Bone Marrow Transplant 22:989\u2013994","journal-title":"Bone Marrow Transplant"},{"key":"996_CR33","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1093\/humrep\/3.suppl_2.39","volume":"3","author":"PG Crosignani","year":"1988","unstructured":"Crosignani PG, Ragni G, Lombroso GC et al (1988) Ovarian stimulation of IVF patients: effects of the reversible hypogonadotropic state induced by GnRH agonist. Hum Reprod 3:39\u201341","journal-title":"Hum Reprod"},{"key":"996_CR34","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.1038\/sj.bjc.6603814","volume":"96","author":"K Lutchman Singh","year":"2007","unstructured":"Lutchman Singh K, Muttukrishna S et al (2007) Predictors of ovarian reserve in young women with breast cancer. Br J Cancer 96:1808\u20131816","journal-title":"Br J Cancer"},{"key":"996_CR35","doi-asserted-by":"crossref","first-page":"3869","DOI":"10.1210\/jc.2006-2374","volume":"92","author":"RD Beek van","year":"2007","unstructured":"van Beek RD, van den Heuvel-Eibrink MM, Laven JS et al (2007) Anti-Mullerian hormone is a sensitive serum marker for gonadal function in women treated for Hodgkin\u2019s lymphoma during childhood. J Clin Endocrinol Metab 92:3869\u20133874","journal-title":"J Clin Endocrinol Metab"},{"key":"996_CR36","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1093\/humupd\/7.6.581","volume":"7","author":"A Bukman","year":"2001","unstructured":"Bukman A, Heineman MJ (2001) Ovarian reserve testing and the use of prognostic models in patients with subfertility. Hum Reprod Update 7:581\u2013590","journal-title":"Hum Reprod Update"},{"key":"996_CR37","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1001\/jama.282.11.1083","volume":"282","author":"JA Berlin","year":"1999","unstructured":"Berlin JA, Rennie D (1999) Measuring the quality of trials: the quality of quality scales. JAMA 282:1083\u20131084","journal-title":"JAMA"},{"key":"996_CR38","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1111\/j.1471-0528.2006.01163.x","volume":"114","author":"J Henderson","year":"2007","unstructured":"Henderson J, Gray R, Brocklehurst P (2007) Systematic review of effects of low-moderate prenatal alcohol exposure on pregnancy outcome. BJOG 114:243\u2013252","journal-title":"BJOG"},{"key":"996_CR39","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","volume":"327","author":"JPT Higgins","year":"2003","unstructured":"Higgins JPT, Thompson SG, Deeks JJ et al (2003) Measuring inconsistency in meta-analyses. BMJ 327:557\u2013560","journal-title":"BMJ"},{"key":"996_CR40","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1093\/jnci\/djj243","volume":"98","author":"CA Sklar","year":"2008","unstructured":"Sklar CA, Mertens AC, Mitby P et al (2008) Premature menopause in survivors of childhood cancer: a report from the childhood cancer survivor study. J Natl Cancer Inst 98:890\u2013896","journal-title":"J Natl Cancer Inst"},{"key":"996_CR41","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/BF02967466","volume":"7","author":"M Matsumoto","year":"2000","unstructured":"Matsumoto M, Miyauchi M, Yamamoto N et al (2000) Investigation of menstruation recovery after LH-RH agonist therapy for premenopausal patients with breast cancer. Breast Cancer 7:237\u2013240","journal-title":"Breast Cancer"},{"key":"996_CR42","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0303-7207(00)00365-8","volume":"169","author":"D Meirow","year":"2000","unstructured":"Meirow D (2000) Reproduction post-chemotherapy in young cancer patients. Mol Cell Endocrinol 169:123\u2013131","journal-title":"Mol Cell Endocrinol"},{"key":"996_CR43","first-page":"3651","volume":"45","author":"KM Ataya","year":"1985","unstructured":"Ataya KM, McKanna JA, Weintraub AM et al (1985) Luteinizing hormone-releasing hormone agonist for the prevention of chemotherapy-induced ovarian follicular loss in rats. Cancer Res 45:3651\u20133656","journal-title":"Cancer Res"},{"key":"996_CR44","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1093\/humrep\/deh120","volume":"19","author":"GS Letterie","year":"2004","unstructured":"Letterie GS (2004) Anovulation in the prevention of cytotoxic-induced follicular attrition and ovarian failure. Hum Reprod 19:831\u2013837","journal-title":"Hum Reprod"},{"key":"996_CR45","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1080\/01443610601056467","volume":"27","author":"A Imai","year":"2007","unstructured":"Imai A, Furui T (2007) Chemotherapy-induced female infertility and protective action of gonadotropin-releasing hormone analogues. J Obstet Gynaecol 27:20\u201324","journal-title":"J Obstet Gynaecol"},{"key":"996_CR46","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1016\/j.fertnstert.2004.12.030","volume":"83","author":"DR Danforth","year":"2005","unstructured":"Danforth DR, Arbogast LK, Friedman CI (2005) Acute depletion of murine primordial follicle reserve by gonadotropin-releasing hormone antagonists. Fertil Steril 83:1333\u20131338","journal-title":"Fertil Steril"},{"key":"996_CR47","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1001\/jama.1979.03300170023020","volume":"242","author":"RM Chapman","year":"1979","unstructured":"Chapman RM, Sutcliffe SB, Malpas JS (1979) Cytotoxic induced ovarian failure in women with Hodgkin\u2019s disease. I. Hormonal function. JAMA 242:1877\u20131881","journal-title":"JAMA"},{"key":"996_CR48","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/0890-6238(94)90013-2","volume":"8","author":"ML Meistrich","year":"1994","unstructured":"Meistrich ML (1994) Failure to demonstrate hormonal protection of chemotherapy-induced fertility reduction in female rats. Reprod Toxicol 8:277\u2013278","journal-title":"Reprod Toxicol"},{"key":"996_CR49","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0303-7207(99)00245-2","volume":"163","author":"AJ Hsueh","year":"2000","unstructured":"Hsueh AJ, McGee EA, Hayashi M et al (2000) Hormonal regulation of early follicle development in the rat ovary. Mol Cell Endocrinol 163:95\u2013100","journal-title":"Mol Cell Endocrinol"},{"key":"996_CR50","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1530\/REP-08-0096","volume":"136","author":"ML Meistrich","year":"2008","unstructured":"Meistrich ML, Shetty G (2008) Hormonal suppression for fertility preservation in males and females. Reproduction 136:691\u2013701","journal-title":"Reproduction"},{"key":"996_CR51","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1093\/humrep\/deh257","volume":"19","author":"D Meirow","year":"2004","unstructured":"Meirow D, Assad G, Dor J et al (2004) The GnRH antagonist cetrorelix reduces cyclophosphamide-induced ovarian follicular destruction in mice. Hum Reprod 19:1294\u20131299","journal-title":"Hum Reprod"},{"key":"996_CR52","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1016\/j.fertnstert.2005.01.089","volume":"83","author":"RK Gupta","year":"2005","unstructured":"Gupta RK, Flaws JA (2005) Gonadotropin-releasing hormone (GnRH) analogues and the ovary: do GnRH antagonists destroy primordial follicles? Fertil Steril 83:1339\u20131342","journal-title":"Fertil Steril"},{"key":"996_CR53","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.1093\/humrep\/9.suppl_2.36","volume":"9","author":"EY Adashi","year":"1994","unstructured":"Adashi EY (1994) Long-term gonadotropin-releasing hormone agonist therapy: the evolving issue of steroidal \u2018add-back\u2019 paradigms. Hum Reprod 9:1380\u20131397","journal-title":"Hum Reprod"},{"key":"996_CR54","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1095\/biolreprod.105.043489","volume":"73","author":"A Nagy","year":"2005","unstructured":"Nagy A, Schally AV (2005) Targeting of cytotoxic luteinizing hormone-releasing hormone analogs to breast, ovarian, endometrial, and prostate cancers. Biol Reprod 73:851\u2013859","journal-title":"Biol Reprod"},{"key":"996_CR55","first-page":"1634","volume":"1","author":"D Meirow","year":"2008","unstructured":"Meirow D, Rabinovici J, Katz D et al (2008) Prevention of severe menorrhagia in oncology patients with treatment-induced thrombocytopenia by luteinizing hormone-releasing hormone agonist and depo-medroxyprogesterone acetate. Cancer 1:1634\u20131641","journal-title":"Cancer"},{"key":"996_CR56","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.ejogrb.2007.03.012","volume":"134","author":"AM Quaas","year":"2007","unstructured":"Quaas AM, Ginsburg ES (2007) Prevention and treatment of uterine bleeding in hematologic malignancy. Eur J Obstet Gynecol Reprod Biol 134:3\u20138","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"996_CR57","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1097\/01.gco.0000193015.96275.2d","volume":"18","author":"E Porcu","year":"2006","unstructured":"Porcu E, Venturoli S (2006) Progress with oocyte cryopreservation. Curr Opin Obstet Gynecol 18:273\u2013279","journal-title":"Curr Opin Obstet Gynecol"},{"key":"996_CR58","first-page":"CD004562","volume":"8","author":"R Sharma","year":"2008","unstructured":"Sharma R, Hamilton A, Beith J (2008) LHRH agonists for adjuvant therapy of early breast cancer in premenopausal women. Cochrane Database Syst Rev 8:CD004562","journal-title":"Cochrane Database Syst Rev"}],"container-title":["Breast Cancer Research and Treatment"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-010-0996-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10549-010-0996-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-010-0996-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T12:32:34Z","timestamp":1559219554000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10549-010-0996-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6,23]]},"references-count":58,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,8]]}},"alternative-id":["996"],"URL":"https:\/\/doi.org\/10.1007\/s10549-010-0996-7","relation":{},"ISSN":["0167-6806","1573-7217"],"issn-type":[{"value":"0167-6806","type":"print"},{"value":"1573-7217","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,6,23]]}}}