{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T06:18:04Z","timestamp":1761718684164,"version":"3.37.3"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2018,3,21]],"date-time":"2018-03-21T00:00:00Z","timestamp":1521590400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100003975","name":"Israel Cancer Association","doi-asserted-by":"publisher","award":["Israeli consortium of hereditary breast cancer"],"award-info":[{"award-number":["Israeli consortium of hereditary breast cancer"]}],"id":[{"id":"10.13039\/501100003975","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Breast Cancer Res Treat"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.1007\/s10549-018-4765-3","type":"journal-article","created":{"date-parts":[[2018,3,20]],"date-time":"2018-03-20T22:19:26Z","timestamp":1521584366000},"page":"399-404","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Mutational analysis of candidate genes in Israeli male breast cancer cases"],"prefix":"10.1007","volume":"170","author":[{"given":"Hagit","family":"Schayek","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hila","family":"Korach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yael","family":"Laitman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rinat","family":"Bernstein-Molho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6745-1733","authenticated-orcid":false,"given":"Eitan","family":"Friedman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,3,21]]},"reference":[{"key":"4765_CR1","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1002\/(SICI)1097-0142(19980801)83:3<498::AID-CNCR19>3.0.CO;2-R","volume":"83","author":"WL Donegan","year":"1998","unstructured":"Donegan WL, Redlich PN, Lang PJ, Gall MT (1998) Carcinoma of the breast in males: a multiinstitutional survey. Cancer 83:498\u2013509","journal-title":"Cancer"},{"issue":"1","key":"4765_CR2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s11912-015-0487-4","volume":"18","author":"RM Ferzoco","year":"2016","unstructured":"Ferzoco RM, Ruddy KJ (2016) The epidemiology of\u00a0male breast cancer. Curr Oncol Rep 18(1):1\u20136","journal-title":"Curr Oncol Rep"},{"issue":"10","key":"4765_CR3","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1038\/nrc3806","volume":"14","author":"L Ottini","year":"2014","unstructured":"Ottini L (2014) Male breast cancer: a rare disease that might uncover underlying pathways of breast cancer. Nat Rev Cancer 14(10):643. https:\/\/doi.org\/10.1038\/nrc3806","journal-title":"Nat Rev Cancer"},{"key":"4765_CR4","first-page":"1361","volume":"58","author":"K Haraldsson","year":"1998","unstructured":"Haraldsson K, Loman N, Zhang QX, Johannsson O, Olsson H, Borg A (1998) BRCA2 germ-line mutations are frequent in male breast cancer patients without a family history of the disease. Cancer Res 58:1361\u20131371","journal-title":"Cancer Res"},{"issue":"1","key":"4765_CR5","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1007\/s10549-012-2062-0","volume":"134","author":"L Ottini","year":"2012","unstructured":"Ottini L, Silvestri V, Rizzolo P, Falchetti M, Zanna I, Saieva C, Masala G, Bianchi S, Manoukian S, Barile M, Peterlongo P, Varesco L, Tommasi S, Russo A, Giannini G, Cortesi L, Viel A, Montagna M, Radice P, Palli D (2012) Clinical and pathologic characteristics of BRCA-positive and BRCA-negative male breast cancer patients: results from a collaborative multicenter study in Italy. Breast Cancer Res Treat 134(1):411\u2013418. https:\/\/doi.org\/10.1007\/s10549-012-2062-0","journal-title":"Breast Cancer Res Treat"},{"issue":"3","key":"4765_CR6","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1007\/s10549-016-4085-4","volume":"161","author":"M Pritzlaff","year":"2017","unstructured":"Pritzlaff M, Summerour P, McFarland R, Li S, Reineke P, Dolinsky JS, Goldgar DE, Shimelis H, Couch FJ, Chao EC, LaDuca H (2017) Male breast cancer in a multi-gene panel testing cohort: insights and unexpected results. Breast Cancer Res Treat 161(3):575\u2013586. https:\/\/doi.org\/10.1007\/s10549-016-4085-4","journal-title":"Breast Cancer Res Treat"},{"key":"4765_CR7","doi-asserted-by":"publisher","first-page":"1888","DOI":"10.1038\/ng1096-185","volume":"14","author":"BB Roa","year":"1996","unstructured":"Roa BB, Boyd AA, Volcik K, Richards CS (1996) Ashkenazi Jewish population frequencies for common mutations in BRCA1 and BRCA2. Nat Genet 14:1888\u20131890","journal-title":"Nat Genet"},{"issue":"Suppl","key":"4765_CR8","first-page":"1805","volume":"65","author":"L Scheuer","year":"1999","unstructured":"Scheuer L, Robson M, Hamper H, Borgen P, Norton L, McDermott D, Pinto M, Hull J, Baum R, Nafa K, Ellis N, Schluger A, Offitt K (1999) Frequency of BRCA mutations among a series of Ashkenazi Jewish men diagnosed with breast cancer. Am J Hum Genet 65(Suppl):1805","journal-title":"Am J Hum Genet"},{"key":"4765_CR9","doi-asserted-by":"publisher","first-page":"1800","DOI":"10.1086\/302678","volume":"65","author":"JP Struewing","year":"1999","unstructured":"Struewing JP, Coriaty ZM, Ron E, Livoff A, Konichezky M, Cohen P, Resnick MB, Lifzchiz-Mercerl B, Lew S, Iscovich J (1999) Founder BRCA1\/2 mutations among male patients with breast cancer in Israel. Am J Hum Genet 65:1800\u20131802","journal-title":"Am J Hum Genet"},{"issue":"3","key":"4765_CR10","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1089\/10906570050501579","volume":"4","author":"RS Sverdlov","year":"2000","unstructured":"Sverdlov RS, Barshack I, Bar Sade RB, Baruch RG, Hirsh-Yehezkel G, Dagan E, Feinmesser M, Figer A, Friedman E (2000) Genetic analyses of male breast cancer in Israel. Genet Test 4(3):313\u2013317","journal-title":"Genet Test"},{"key":"4765_CR11","doi-asserted-by":"publisher","unstructured":"Peterlongo P, Catucci I, Colombo M, Caleca L, Mucaki E, Bogliolo M, Marin M, Damiola F, Bernard L, Pensotti V, Volorio S, Dall\u2019Olio V, Meindl A, Bartram C, Sutter C, Surowy H, Sornin V, Dondon MG, Eon-Marchais S, Stoppa-Lyonnet D, Andrieu N, Sinilnikova OM; GENESIS., Mitchell G, James PA, Thompson E; kConFab.; SWE-BRCA., Marchetti M, Verzeroli C, Tartari C, Capone GL, Putignano AL, Genuardi M, Medici V, Marchi I, Federico M, Tognazzo S, Matricardi L, Agata S, Dolcetti R, Della Puppa L, Cini G, Gismondi V, Viassolo V, Perfumo C, Mencarelli MA, Baldassarri M, Peissel B, Roversi G, Silvestri V, Rizzolo P, Spina F, Vivanet C, Tibiletti MG, Caligo MA, Gambino G, Tommasi S, Pilato B, Tondini C, Corna C, Bonanni B, Barile M, Osorio A, Benitez J, Balestrino L, Ottini L, Manoukian S, Pierotti MA, Renieri A, Varesco L, Couch FJ, Wang X, Devilee P, Hilbers FS, van Asperen CJ, Viel A, Montagna M, Cortesi L, Diez O, Balma\u00f1a J, Hauke J, Schmutzler RK, Papi L, Pujana MA, L\u00e1zaro C, Falanga A, Offit K, Vijai J, Campbell I, Burwinkel B, Kvist A, Ehrencrona H, Mazoyer S, Pizzamiglio S, Verderio P, Surralles J, Rogan PK, Radice P (2015) FANCM c.5791C\u2009>\u2009T nonsense mutation (rs144567652) induces exon skipping, affects DNA repair activity and is a familial breast cancer risk factor. Hum Mol Genet 24(18):5345\u20135355. https:\/\/doi.org\/10.1093\/hmg\/ddv251","DOI":"10.1093\/hmg\/ddv251"},{"key":"4765_CR12","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/j.breast.2017.12.013","volume":"38","author":"V Silvestri","year":"2017","unstructured":"Silvestri V, Rizzolo P, Zelli V, Valentini V, Zanna I, Bianchi S, Tibiletti MG, Varesco L, Russo A, Tommasi S, Coppa A, Capalbo C, Calistri D, Viel A, Cortesi L, Manoukian S, Bonanni B, Montagna M, Palli D, Radice P, Peterlongo P, Ottini L (2017) A possible role of FANCM mutations in male breast cancer susceptibility: results from a multicenter study in Italy. Breast 38:92\u201397. https:\/\/doi.org\/10.1016\/j.breast.2017.12.013","journal-title":"Breast"},{"issue":"1","key":"4765_CR13","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1038\/ng879","volume":"31","author":"Meijers-Heijboer H, van den Ouweland A, Klijn J, Wasielewski M, de Snoo A, Oldenburg R, Hollestelle A, Houben M, Crepin E, van Veghel-Plandsoen M, Elstrodt F, van Duijn C, Bartels C, Meijers C, Schutte M, McGuffog L, Thompson D, Easton D, Sodha N, Seal S, Barfoot R, Mangion J, Chang-Claude J, Eccles D, Eeles R, Evans DG, Houlston R, Murday V, Narod S, Peretz T, Peto J, Phelan C, Zhang HX, Szabo C, Devilee P, Goldgar D, Futreal PA, Nathanson KL, Weber B, Rahman N, Stratton MR, CHEK2-Breast Cancer Consortium","year":"2002","unstructured":"Meijers-Heijboer H, van den Ouweland A, Klijn J, Wasielewski M, de Snoo A, Oldenburg R, Hollestelle A, Houben M, Crepin E, van Veghel-Plandsoen M, Elstrodt F, van Duijn C, Bartels C, Meijers C, Schutte M, McGuffog L, Thompson D, Easton D, Sodha N, Seal S, Barfoot R, Mangion J, Chang-Claude J, Eccles D, Eeles R, Evans DG, Houlston R, Murday V, Narod S, Peretz T, Peto J, Phelan C, Zhang HX, Szabo C, Devilee P, Goldgar D, Futreal PA, Nathanson KL, Weber B, Rahman N, Stratton MR, CHEK2-Breast Cancer Consortium (2002) Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations. Nat Genet 31(1):55\u201359","journal-title":"Nat Genet"},{"issue":"2","key":"4765_CR14","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/j.canlet.2004.07.002","volume":"215","author":"N Sodha","year":"2004","unstructured":"Sodha N, Wilson C, Bullock SL, Phillimore H, Houlston RS, Eeles RA (2004) Analysis of familial male breast cancer for germline mutations in CHEK2. Cancer Lett 215(2):187\u2013189","journal-title":"Cancer Lett"},{"issue":"2","key":"4765_CR15","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1007\/s10549-008-0162-7","volume":"116","author":"M Wasielewski","year":"2009","unstructured":"Wasielewski M, den Bakker MA, van den Ouweland A, Meijer-van Gelder ME, Portengen H, Klijn JG, Meijers-Heijboer H, Foekens JA, Schutte M (2009) CHEK2 1100delC and male breast cancer in the Netherlands. Breast Cancer Res Treat 116(2):397\u2013400. https:\/\/doi.org\/10.1007\/s10549-008-0162-7","journal-title":"Breast Cancer Res Treat"},{"issue":"1","key":"4765_CR16","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1186\/s12885-017-3631-8","volume":"17","author":"S Hallamies","year":"2017","unstructured":"Hallamies S, Pelttari LM, Poikonen-Saksela P, Jekunen A, Jukkola-Vuorinen A, Auvinen P, Blomqvist C, Aittom\u00e4ki K, Mattson J, Nevanlinna H (2017) CHEK2 c.1100delC mutation is associated with an increased risk for male breast cancer in Finnish patient population. BMC Cancer 17(1):620\u2013624. https:\/\/doi.org\/10.1186\/s12885-017-3631-8","journal-title":"BMC Cancer"},{"issue":"3","key":"4765_CR17","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1002\/ijc.11384","volume":"108","author":"K Syrj\u00e4koski","year":"2004","unstructured":"Syrj\u00e4koski K, Kuukasj\u00e4rvi T, Auvinen A, Kallioniemi OP (2004) CHEK2 1100delC is not a risk factor for male breast cancer population. Int J Cancer 108(3):475\u2013476","journal-title":"Int J Cancer"},{"issue":"2","key":"4765_CR18","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1007\/s10689-007-9153-9","volume":"7","author":"DG Evans","year":"2008","unstructured":"Evans DG, Bulman M, Young K, Howard E, Bayliss S, Wallace A, Lalloo F (2008) BRCA1\/2 mutation analysis in male breast cancer families from North West England. Fam Cancer 7(2):113\u20131137","journal-title":"Fam Cancer"},{"key":"4765_CR19","doi-asserted-by":"publisher","unstructured":"Apostolou P, Fostira F, Papamentzelopoulou M, Michelli M, Panopoulos C, Fountzilas G, Konstantopoulou I, Voutsinas GE, Yannoukakos D (2015) CHEK2 c.1100delC allele is rarely identified in Greek breast cancer cases. Cancer Genet 208(4):129\u2013134. https:\/\/doi.org\/10.1016\/j.cancergen.2015.02.006","DOI":"10.1016\/j.cancergen.2015.02.006"},{"issue":"3","key":"4765_CR20","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1002\/ijc.11603","volume":"108","author":"T Ohayon","year":"2004","unstructured":"Ohayon T, Gal I, Baruch RG, Szabo C, Friedman E (2004) CHEK2*1100delC and male breast cancer risk in Israel. Int J Cancer 108(3):479\u2013480","journal-title":"Int J Cancer"},{"issue":"4","key":"4765_CR21","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1093\/hmg\/ddi052","volume":"14","author":"A Shaag","year":"2005","unstructured":"Shaag A, Walsh T, Renbaum P, Kirchhoff T, Nafa K, Shiovitz S, Mandell JB, Welcsh P, Lee MK, Ellis N, Offit K, Levy-Lahad E, King MC (2005) Functional and genomic approaches reveal an ancient CHEK2 allele associated with breast cancer in the Ashkenazi Jewish population. Hum Mol Genet 14(4):555\u2013563","journal-title":"Hum Mol Genet"},{"issue":"1","key":"4765_CR22","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1007\/s10549-007-9689-2","volume":"110","author":"M Falchetti","year":"2008","unstructured":"Falchetti M, Lupi R, Rizzolo P, Ceccarelli K, Zanna I, Cal\u00f2 V, Tommasi S, Masala G, Paradiso A, Gulino A, Giannini G, Russo A, Palli D, Ottini L (2008) BRCA1\/BRCA2 rearrangements and CHEK2 common mutations are infrequent in Italian male breast cancer cases. Breast Cancer Res Treat 110(1):161\u2013167","journal-title":"Breast Cancer Res Treat"},{"issue":"11","key":"4765_CR23","doi-asserted-by":"publisher","first-page":"1591","DOI":"10.1038\/ejhg.2016.57","volume":"24","author":"H Byers","year":"2016","unstructured":"Byers H, Wallis Y, van Veen EM, Lalloo F, Reay K, Smith P, Wallace AJ, Bowers N, Newman WG, Evans DG (2016) Sensitivity of BRCA1\/2 testing in high-risk breast\/ovarian\/male breast cancer families: little contribution of comprehensive RNA\/NGS panel testing. Eur J Hum Genet 24(11):1591\u20131597. https:\/\/doi.org\/10.1038\/ejhg.2016.57","journal-title":"Eur J Hum Genet"},{"issue":"6","key":"4765_CR24","doi-asserted-by":"publisher","first-page":"e0178450","DOI":"10.1371\/journal.pone.0178450","volume":"12","author":"JL Stafford","year":"2017","unstructured":"Stafford JL, Dyson G, Levin NK, Chaudhry S, Rosati R, Kalpage H, Wernette C, Petrucelli N, Simon MS, Tainsky MA (2017) Reanalysis of BRCA1\/2 negative high risk ovarian cancer patients reveals novel germline risk loci and insights into missing heritability. PLoS ONE 12(6):e0178450. https:\/\/doi.org\/10.1371\/journal.pone.0178450","journal-title":"PLoS ONE"},{"issue":"1\u20132","key":"4765_CR25","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.cancergen.2015.11.003","volume":"209","author":"H Schayek","year":"2016","unstructured":"Schayek H, De Marco L, Starinsky-Elbaz S, Rossette M, Laitman Y, Bastos-Rodrigues L, da Silva Filho AL, Friedman E (2016) The rate of recurrent BRCA1, BRCA2, and TP53 mutations in the general population, and unselected ovarian cancer cases, in Belo Horizonte. Brazil Cancer Genet 209(1\u20132):50\u201352. https:\/\/doi.org\/10.1016\/j.cancergen.2015.11.003","journal-title":"Brazil Cancer Genet"},{"key":"4765_CR26","doi-asserted-by":"publisher","first-page":"1428","DOI":"10.1038\/bjc.1997.574","volume":"76","author":"E Mavraki","year":"1997","unstructured":"Mavraki E, Gray IC, Bishop DT, Spurr NK (1997) Germline BRCA2 mutations in men with breast cancer. Br J Cancer 76:1428\u20131431","journal-title":"Br J Cancer"},{"key":"4765_CR27","first-page":"995","volume":"59","author":"B Csokay","year":"1999","unstructured":"Csokay B, Udvarhelyi N, Sulyok Z, Besznyak I, Ramus S, Ponder B, Olah E (1999) High frequency of germ-line BRCA2 mutations among Hungarian male breast cancer patients without family history. Cancer Res 59:995\u2013998","journal-title":"Cancer Res"},{"issue":"1","key":"4765_CR28","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1038\/ng0596-117","volume":"13","author":"S Thorlacius","year":"1996","unstructured":"Thorlacius S, Olafsdottir G, Tryggvadottir L, Neuhausen S, Jonasson JG, Tavtigian SV, Tulinius H, Ogmundsdottir HM, Eyfj\u00f6rd JE (1996) A single BRCA2 mutation in male and female breast cancer families from Iceland with varied cancer phenotypes. Nat Genet 13(1):117\u2013119","journal-title":"Nat Genet"},{"issue":"5","key":"4765_CR29","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1593\/neo.04193","volume":"6","author":"K Syrj\u00e4koski","year":"2004","unstructured":"Syrj\u00e4koski K, Kuukasj\u00e4rvi T, Waltering K, Haraldsson K, Auvinen A, Borg A, Kainu T, Kallioniemi OP, Koivisto PA (2004) BRCA2 mutations in 154 finnish male breast cancer patients. Neoplasia 6(5):541\u2013545","journal-title":"Neoplasia"},{"issue":"12","key":"4765_CR30","doi-asserted-by":"publisher","first-page":"1647","DOI":"10.1001\/jamaoncol.2017.1996","volume":"3","author":"T Walsh","year":"2017","unstructured":"Walsh T, Mandell JB, Norquist BM, Casadei S, Gulsuner S, Lee MK, King MC (2017) Genetic predisposition to breast cancer due to mutations other than BRCA1 and BRCA2 founder alleles among Ashkenazi Jewish Women. JAMA Oncol 3(12):1647\u20131653. https:\/\/doi.org\/10.1001\/jamaoncol.2017","journal-title":"JAMA Oncol"},{"issue":"4","key":"4765_CR31","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1200\/JCO.2007.12.5922","volume":"26","author":"M Weischer","year":"2008","unstructured":"Weischer M, Bojesen SE, Ellervik C, Tybjaerg-Hansen A, Nordestgaard BG (2008) CHEK2*1100delC genotyping for clinical assessment of breast cancer risk: meta-analyses of 26,000 patient cases and 27,000 controls. J Clin Oncol 26(4):542\u2013548. https:\/\/doi.org\/10.1200\/JCO.2007.12.5922","journal-title":"J Clin Oncol"},{"issue":"11","key":"4765_CR32","first-page":"791","volume":"9","author":"Y Laitman","year":"2007","unstructured":"Laitman Y, Kaufman B, Lahad EL, Papa MZ, Friedman E (2007) Germline CHEK2 mutations in Jewish Ashkenazi women at high risk for breast cancer. Isr Med Assoc J. 9(11):791\u2013796","journal-title":"Isr Med Assoc J."},{"issue":"6","key":"4765_CR33","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1159\/000484800","volume":"5","author":"RB Bar-Sade","year":"1997","unstructured":"Bar-Sade RB, Theodor L, Gak E, Kruglikova A, Hirsch-Yechezkel G, Modan B, Kuperstein G, Seligsohn U, Rechavi G, Friedman E (1997) Could the 185delAG BRCA1 mutation be an ancient Jewish mutation? Eur J Hum Genet 5(6):413\u2013416","journal-title":"Eur J Hum Genet"},{"issue":"2","key":"4765_CR34","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1089\/109065701753145628","volume":"5","author":"R Shtoyerman-Chen","year":"2001","unstructured":"Shtoyerman-Chen R, Friedman E, Figer A, Carmel M, Patael Y, Rath P, Fidder HH, Bar-Meir S, Theodor L (2001) The I1307\u00a0K APC polymorphism: prevalence in non-Ashkenazi Jews and evidence for a founder effect. Genet Test 5(2):141\u2013146","journal-title":"Genet Test"},{"issue":"2","key":"4765_CR35","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1038\/ejhg.2012.124","volume":"21","author":"Y Laitman","year":"2013","unstructured":"Laitman Y, Feng BJ, Zamir IM, Weitzel JN, Duncan P, Port D, Thirthagiri E, Teo SH, Evans G, Latif A, Newman WG, Gershoni-Baruch R, Zidan J, Shimon-Paluch S, Goldgar D, Friedman E (2013) Haplotype analysis of the 185delAG BRCA1 mutation in ethnically diverse populations. Eur J Hum Genet 21(2):212\u2013216. https:\/\/doi.org\/10.1038\/ejhg.2012.124","journal-title":"Eur J Hum Genet"}],"container-title":["Breast Cancer Research and Treatment"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10549-018-4765-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-018-4765-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-018-4765-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,13]],"date-time":"2019-10-13T01:48:28Z","timestamp":1570931308000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10549-018-4765-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,21]]},"references-count":35,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["4765"],"URL":"https:\/\/doi.org\/10.1007\/s10549-018-4765-3","relation":{},"ISSN":["0167-6806","1573-7217"],"issn-type":[{"type":"print","value":"0167-6806"},{"type":"electronic","value":"1573-7217"}],"subject":[],"published":{"date-parts":[[2018,3,21]]},"assertion":[{"value":"22 January 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 March 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 March 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"All authors confirm that they have no conflict of interest with the data reported herein.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}